azathioprine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 7 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of acute severe hepatitis resulting from masitinib in a young amyotrophic lateral sclerosis patient." | 7.81 | Autoimmune-like hepatitis during masitinib therapy in an amyotrophic lateral sclerosis patient. ( Camacho, J; Gamez, J; Salvado, M; Simon-Talero, M; Vargas, V; Vidal, M, 2015) |
| "We report a case of acute severe hepatitis resulting from masitinib in a young amyotrophic lateral sclerosis patient." | 3.81 | Autoimmune-like hepatitis during masitinib therapy in an amyotrophic lateral sclerosis patient. ( Camacho, J; Gamez, J; Salvado, M; Simon-Talero, M; Vargas, V; Vidal, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Salvado, M | 1 |
| Vargas, V | 1 |
| Vidal, M | 1 |
| Simon-Talero, M | 1 |
| Camacho, J | 1 |
| Gamez, J | 1 |
| Bentes, C | 1 |
| de Carvalho, M | 1 |
| Valente, I | 1 |
| Sales Luis, ML | 1 |
| da Silva, JP | 1 |
| Jerusalem, F | 1 |
| Overgaard, K | 1 |
| Werdelin, L | 2 |
| Sørensen, H | 1 |
| Mogensen, P | 2 |
| Boysen, G | 2 |
| Jensen, TS | 1 |
| Conradi, S | 1 |
| Ronnevi, LO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amyotrophic Lateral Sclerosis and the Innate Immune System[NCT02869048] | 375 participants (Anticipated) | Observational | 2016-06-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
[Treatment of myopathies and spinal muscular atrophies (author's transl)].
Topics: Amyotrophic Lateral Sclerosis; Azathioprine; Collagen Diseases; Dermatomyositis; Glycogen Storage Di | 1978 |
6 other studies available for azathioprine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
ALSUntangled 58: Azathioprine.
Topics: Amyotrophic Lateral Sclerosis; Azathioprine; Humans | 2021 |
Autoimmune-like hepatitis during masitinib therapy in an amyotrophic lateral sclerosis patient.
Topics: Adult; Amyotrophic Lateral Sclerosis; Azathioprine; Benzamides; Biopsy; Chemical and Drug Induced Li | 2015 |
Amyotrophic lateral sclerosis syndrome associated with connective tissue disease; improvement after immunosuppressive therapy. A long-term follow-up case.
Topics: Amyotrophic Lateral Sclerosis; Anti-Inflammatory Agents; Azathioprine; Connective Tissue Diseases; F | 1999 |
Cytotoxic activity in plasma from patients with amyotrophic lateral sclerosis.
Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Azathioprine; Female; Hemolysis; Humans; Mal | 1991 |
Immunosuppressive treatment of patients with amyotrophic lateral sclerosis.
Topics: Administration, Oral; Adult; Aged; Amyotrophic Lateral Sclerosis; Azathioprine; Female; Humans; Infu | 1990 |
Effect of immunosuppression on cytotoxic activity in amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Azathioprine; Cytotoxicity, Immunologic; Drug Therapy, Combinat | 1987 |