azaguanine and Neoplasms

azaguanine has been researched along with Neoplasms* in 42 studies

Reviews

3 review(s) available for azaguanine and Neoplasms

ArticleYear
Rationale of combination chemotherapy based on preclinical experiments.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:2

    Topics: Animals; Antineoplastic Agents; Azaguanine; Carcinoma; Cytarabine; Drug Synergism; Humans; Hydroxyurea; Immunotherapy; Leukemia L1210; Lung Neoplasms; Melanoma; Neoplasms; Thiosemicarbazones; Time Factors

1973
[CHEMOTHERAPY OF UTERINE CERVIX CARCINOMA].
    Rivista di ostetricia e ginecologia, 1964, Volume: 19

    Topics: Antineoplastic Agents; Azaguanine; Aziridines; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Fluorouracil; Humans; Infusions, Parenteral; Melphalan; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Triaziquone; Uracil Mustard; Uterine Cervical Neoplasms; Vinblastine

1964
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
    Annual review of biochemistry, 1963, Volume: 32

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil

1963

Other Studies

39 other study(ies) available for azaguanine and Neoplasms

ArticleYear
Induction of 8-azaguanine-resistant mutation and neoplastic transformation of hamster embryonic cells by coadministration of sodium nitrite and aminopyrine.
    Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:2

    Hamster embryos in utero on the 11th or 12th day of gestation were treated simultaneously with aminopyrine (Ap) and sodium nitrite (NaNO2) by oral administration of the compounds to the mothers by stomach tube. For measurement of induction of 8 AG-resistant mutations, the embryonic cells from treated and control mothers were cultured in MEM plus 10% FBS for 72 h and then selected in medium containing 10 or 20 microgram/ml of 8 AG. The number of 8 AG-resistant colonies was markedly increased after co-administration of Ap and NaNO2, and slight induction of mutations was also observed in cells from mothers given NaNO2 alone. This treatment also caused morphological or malignant transformation of cultured cells. About 5- to 6-fold increase in the number of transformed colonies was observed in cells from mothers given Ap plus NaNO2. Cells from the transformed colonies produced tumors when implanted into the cheek pouches of young golden hamsters. These tumors were diagnosed as pleomorphic fibrosarcomas. Similar results were obtained with cells from embryos treated transplacentally with NDMA as positive controls. A single transplacental oral application of Ap at 200 mg/kg or of NaNO2 had only slight biological actions to the cultured embryonic cells. NDMA was produced in the stomach of animals treated simultaneously with Ap and NaNO2. A small amount of NDMA was also detected in the stomach after a single dose of NaNO2.

    Topics: Abnormalities, Drug-Induced; Aminopyrine; Animals; Azaguanine; Cells, Cultured; Cricetinae; Dimethylnitrosamine; Female; In Vitro Techniques; Maternal-Fetal Exchange; Mutation; Neoplasms; Nitrites; Pregnancy; Sodium Nitrite

1980
Studies on the isolation and properties of drug resistant mutants from a human malignant cell line.
    Indian journal of cancer, 1968, Volume: 5, Issue:3

    Topics: Aminopterin; Azaguanine; Cell Line; Culture Techniques; Humans; Mutation; Neoplasms

1968
[DRUG THERAPY OF UTERINE CANCER].
    [Sanfujinka chiryo] Obstetrical and gynecological therapy, 1964, Volume: 60

    Topics: Antineoplastic Agents; Azaguanine; Blood Chemical Analysis; Catalase; Clinical Enzyme Tests; Deoxyribonucleases; DNA; Female; Fructose-Bisphosphate Aldolase; Humans; L-Lactate Dehydrogenase; Metabolism; Mitomycin; Mitomycins; Neoplasms; Physiology; Ribonucleases; Uterine Cervical Neoplasms; Uterine Neoplasms

1964
INFLUENCES OF ANTICANCER AGENTS ON THE METABOLISM OF DELTA-AMINOLEVULINIC ACID IN MORMAL AND TUMOR-BEARING MICE.
    Gan, 1964, Volume: 55

    Topics: Alkylating Agents; Amino Acids; Aminolevulinic Acid; Aminopterin; Animals; Antineoplastic Agents; Azaguanine; Blood Chemical Analysis; Carcinoma, Ehrlich Tumor; Catalase; Copper; Folic Acid Antagonists; Hemoglobins; Hydro-Lyases; Iron; Levulinic Acids; Liver; Mercaptopurine; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Proteins; Rats; Research

1964
INCORPORATION OF 8-AZAGUANINE AND GROWTH INHIBITION IN MAMMALIAN SPINNER CULTURES.
    Experimental cell research, 1964, Volume: 34

    Topics: Azaguanine; Carbon Isotopes; Cell Biology; DNA; DNA, Neoplasm; Guanine; Lysine; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Pharmacology; Proteins; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques; Urethane

1964
THE ADVERSE EFFECTS OF CANCER CHEMOTHERAPY.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Antineoplastic Agents; Azaguanine; Carcinoma, Ehrlich Tumor; Cortisone; Cyclophosphamide; Dactinomycin; Mechlorethamine; Mice; Mitomycin; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma; Sarcoma, Yoshida; Thiotepa; Toxicology

1964
IN VITRO CULTURE OF YOSHIDA SARCOMA CELLS: METHODS FOR DETERMINING ACQUIRED RESISTANCE TO DRUGS.
    National Cancer Institute monograph, 1964, Volume: 16

    Topics: Animals; Antineoplastic Agents; Azaguanine; Culture Media; Cyclophosphamide; Dactinomycin; Drug Tolerance; Fluorouracil; Glucosamine; Histocytochemistry; In Vitro Techniques; Mechlorethamine; Mercaptopurine; Mitomycin; Mitomycins; Neoplasm Transplantation; Neoplasms; Nitrogen Mustard Compounds; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Experimental; Sarcoma, Yoshida; Thiotepa; Tissue Culture Techniques

1964
Influences of anticancer agents on the activities of liver catalase, uricase, and xanthine oxidase in normal and tumor-bearing mice.
    Gan, 1963, Volume: 54

    Topics: Aminopterin; Animals; Antineoplastic Agents; Azaguanine; Carboxylic Acids; Carcinoma, Ehrlich Tumor; Catalase; Cyclopentanes; Liver; Mercaptopurine; Methotrexate; Mice; N-Glycosyl Hydrolases; Neoplasms; Oxidoreductases; Thiotepa; Urate Oxidase; Xanthine Oxidase

1963
THE EFFECT OF CHEMOTHERAPEUTIC AGENTS UPON THE METABOLISM OF INTACT HUMAN CANCER CELLS: AN IN VITRO TECHNIC FOR CELL SENSITIVITY.
    Clinical chemistry, 1963, Volume: 102

    Topics: Aminopterin; Antineoplastic Agents; Azaguanine; Carbohydrate Metabolism; In Vitro Techniques; Lactates; Leukemia; Leukocytes; Mechlorethamine; Mercaptopurine; Metabolism; Neoplasms; Prednisone; Research; Thiotepa; Vinblastine

1963
THERAPEUTIC EFFECT OF ANTICANCER DRUGS ON SKIN CANCER.
    Kyushu journal of medical science, 1963, Volume: 14

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Headache; Japan; Leukopenia; Middle Aged; Mitomycin; Neoplasms; Nitrogen Mustard Compounds; Prognosis; Skin Neoplasms; Toxicology; Uracil Mustard

1963
DNA transformation studies with mammalian cells in culture.
    Journal of cellular and comparative physiology, 1962, Volume: 60

    Topics: Animals; Azaguanine; DNA; DNA, Neoplasm; Humans; Leukemia; Leukemia, Lymphoid; Lymphocytes; Neoplasms

1962
[Action of 6-mercaptopurine and of 8-azaguanine on Galliera sarcoma in the rat].
    Bollettino della Societa italiana di biologia sperimentale, 1960, Jun-30, Volume: 36

    Topics: Animals; Azaguanine; Mercaptopurine; Neoplasms; Rats; Sarcoma

1960
[Findings on 8-azaguanine used in man in cancer therapy].
    Bulletin de l'Association francaise pour l'etude du cancer, 1957, Volume: 44, Issue:4

    Topics: Antineoplastic Agents; Azaguanine; Guanine; Neoplasms

1957
[Studies upon the chemotherapy of experimental malignant tumors with a new preparation of cobaltous bis-histidine chelate compound carrying 8-azaguanine].
    Gan, 1957, Volume: 48, Issue:4

    Topics: Animals; Antineoplastic Agents; Azaguanine; Guanine; Histidine; Neoplasms; Neoplasms, Experimental

1957
[Clinical experience of some anti-tumor substances. 2. Therapeutic effect of sarkomycin, actinomycin J and 8-azaguanine on malignant growth].
    Gan, 1956, Volume: 47, Issue:3-4

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Azaguanine; Dactinomycin; Dermatologic Agents; Guanine; Neoplasms

1956
Combination chemotherapy of mouse tumors with 8-azaguanine and flavotin.
    Cancer research, 1955, Volume: 15, Issue:6

    Topics: Animals; Azaguanine; Breast Neoplasms; Drug Therapy, Combination; Guanine; Humans; Leukemia, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Riboflavin

1955
[Effects of 8-azaguanine on malignant tumors. III. Its effects on the Yoshida sarcoma; estimation of DNA content].
    Gan, 1955, Volume: 46, Issue:2-3

    Topics: Animals; Azaguanine; DNA; Guanine; Neoplasms; Nucleic Acids; Ploidies; Sarcoma; Sarcoma, Yoshida

1955
The influence of 8-azaguanine on tumors and enhancement.
    Gan, 1955, Volume: 46, Issue:2-3

    Topics: Animals; Azaguanine; Guanine; Leadership; Neoplasms; Neoplasms, Experimental; Refractive Surgical Procedures

1955
[Clinical studies on cancer chemotherapy. IV. 8-Azaguanine].
    Gan, 1955, Volume: 46, Issue:2-3

    Topics: Animals; Azaguanine; Biomedical Research; Guanine; Neoplasms

1955
The incorporation of 8-azaguanine into nucleic acids of tumor-bearing mice.
    The Journal of biological chemistry, 1954, Volume: 206, Issue:1

    Topics: Animals; Azaguanine; Guanine; Liver; Mice; Neoplasms; Nucleic Acids; Sarcoma; Sarcoma, Experimental

1954
[Effect of 8-azaguanine on malignant tumor].
    Gan, 1954, Volume: 45, Issue:2-3

    Topics: Animals; Azaguanine; Guanine; Neoplasms; Neoplasms, Experimental

1954
[Enzymatic deamination of 8-azaguanine by ascites tumors in rats].
    Gan, 1954, Volume: 45, Issue:2-3

    Topics: Animals; Ascites; Azaguanine; Carcinoma, Ehrlich Tumor; Deamination; Guanine; Neoplasms; Rats

1954
The effects of tumor growth, x-radiation, and 8-azaguanine on the incorporation of adenine into nucleic acids of mice.
    Cancer research, 1954, Volume: 14, Issue:11

    Topics: Adenine; Animals; Azaguanine; Guanine; Mice; Neoplasms; Nucleic Acids; Sarcoma; X-Rays

1954
The effect of azaguanine on the incorporation of guanine and of 4-amino-5-imidazolecarboxamide into tumor-bearing mice.
    The Journal of biological chemistry, 1953, Volume: 201, Issue:1

    Topics: Aminoimidazole Carboxamide; Animals; Azaguanine; Guanine; Imidazoles; Mice; Neoplasms

1953
Combination chemotherapy of cancer: potentiation of carcinostatic action of 8-azaguanine by a riboflavin analog.
    Cancer research, 1953, Volume: 13, Issue:10

    Topics: Animals; Azaguanine; Drug Therapy, Combination; Guanine; Neoplasms; Neoplasms, Experimental; Organic Chemicals; Riboflavin

1953
[8-Azaguanine in the therapy of gynecologic malignant tumors].
    Gan, 1953, Volume: 44, Issue:2-3

    Topics: Azaguanine; Female; Genital Neoplasms, Female; Genitalia; Genitalia, Female; Guanine; Humans; Neoplasms

1953
[Effect of purine antagonist (8-azaguanine) on malignant tumor].
    Gan, 1953, Volume: 44, Issue:2-3

    Topics: Antimetabolites; Azaguanine; Guanine; Neoplasms

1953
Observations on the effects of administration of guanazolo in patients with disseminated neoplasms.
    Cancer, 1952, Volume: 5, Issue:6

    Topics: Azaguanine; Guanine; Neoplasms

1952
Combination chemotherapy of cancer: potentiation of carcinostatic activity of 8-azaguanine by 6-formylpteridine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 81, Issue:3

    Topics: Animals; Antimetabolites; Azaguanine; Drug Therapy, Combination; Folic Acid; Guanine; Neoplasms; Neoplasms, Experimental

1952
Combination chemotherapy of cancer with 8-azaguanine and a riboflavin analog.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 81, Issue:1

    Topics: Animals; Azaguanine; Drug Therapy, Combination; Guanine; Inorganic Chemicals; Neoplasms; Neoplasms, Experimental; Riboflavin

1952
A clinica study of the effect of guanazolo in neoplastic diseases.
    The Harlem Hospital bulletin, 1952, Volume: 4, Issue:4

    Topics: Azaguanine; Guanine; Neoplasms

1952
Enzymatic deamination of 8-azaguanine in normal and neoplastic tissues.
    Cancer research, 1952, Volume: 12, Issue:7

    Topics: Amidohydrolases; Azaguanine; Deamination; Neoplasms

1952
Further evidence on the mode of action of 8-azaguanine (guanazolo) in tumor inhibition.
    Cancer research, 1951, Volume: 11, Issue:3

    Topics: Azaguanine; Guanine; Neoplasms

1951
Metabolite antagonists in cancer; guanazolo.
    Acta - Unio Internationalis Contra Cancrum, 1951, Volume: 7, Issue:3

    Topics: Animals; Azaguanine; Humans; Neoplasms; Neoplasms, Experimental

1951
The effect of azaguanine on mitosis in normal and neoplastic tissues.
    Cancer, 1950, Volume: 3, Issue:5

    Topics: Azaguanine; Guanine; Mitosis; Neoplasms

1950
Studies on the distribution of radioactive 8-azaguanine (guanazolo) in mice with Eo 771 tumors.
    Cancer research, 1950, Volume: 10, Issue:10

    Topics: Animals; Azaguanine; Guanine; Mice; Neoplasms

1950
Studies on the mechanism of action of chemotherapeutic agents in cancer. IV. Relationship of guanine and guanylic acid to the action of guanazolo on lymphoid tumors in mice and rats.
    Journal of the National Cancer Institute, 1950, Volume: 11, Issue:2

    Topics: Animals; Antineoplastic Agents; Azaguanine; Guanine; Guanosine Monophosphate; Lymphoma; Mice; Neoplasms; Rats

1950
The effect of 5-amino-7-hydroxy-1H-v-triazolo (d) pyrimidine (guanazolo) on variety of neoplasms in experimental animals.
    Cancer research, 1950, Volume: 10, Issue:3

    Topics: Animals; Azaguanine; Neoplasms; Pyrimidines

1950
The effect of 8-azaguanine on the growth of carcinoma, sarcoma, osteogenic sarcoma, lymphosarcoma and melanoma in animals.
    Cancer research, 1950, Volume: 10, Issue:3

    Topics: Animals; Azaguanine; Bone Neoplasms; Humans; Lymphoma, Non-Hodgkin; Melanoma; Neoplasms; Osteosarcoma; Sarcoma

1950