azaguanine and Multiple-Myeloma

azaguanine has been researched along with Multiple-Myeloma* in 1 studies

Other Studies

1 other study(ies) available for azaguanine and Multiple-Myeloma

Article	Year
Immunoglobulin G and free kapa-chain synthesis in different clones of a hybrid cell line. Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:12 13 clonal cell lines were isolated from a hybrid cell population established by cell fusion between cloned BALB/c myeloma cells that were resistant to 8-azaguanine and produced immunoglobulin G and free kappa chain and C(67)BL/6n lymphoma cells that were resistant to bromodeoxyuridine and did not produce immunoglobulins. Some of the histocompatibility-2 antigens of both parental cell lines could be demonstrated on all of the hybrid clones. 11 clones synthesized only free kappa chain. Two clones synthesized IgG of BALB/c type, as well as free kappa chain. These clones had higher chromosome number than did the clones that synthesized only kappa chains. Topics: Animals; Antigens; Azaguanine; Bromodeoxyuridine; Cell Fusion; Cell Line; Clone Cells; Complement System Proteins; Culture Media; Histocompatibility; Hybrid Cells; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulins; Karyotyping; Lymphoma; Mice; Multiple Myeloma; Rabbits; Species Specificity	1971

Article

Year

Immunoglobulin G and free kapa-chain synthesis in different clones of a hybrid cell line.

Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:12

13 clonal cell lines were isolated from a hybrid cell population established by cell fusion between cloned BALB/c myeloma cells that were resistant to 8-azaguanine and produced immunoglobulin G and free kappa chain and C(67)BL/6n lymphoma cells that were resistant to bromodeoxyuridine and did not produce immunoglobulins. Some of the histocompatibility-2 antigens of both parental cell lines could be demonstrated on all of the hybrid clones. 11 clones synthesized only free kappa chain. Two clones synthesized IgG of BALB/c type, as well as free kappa chain. These clones had higher chromosome number than did the clones that synthesized only kappa chains.

Topics: Animals; Antigens; Azaguanine; Bromodeoxyuridine; Cell Fusion; Cell Line; Clone Cells; Complement System Proteins; Culture Media; Histocompatibility; Hybrid Cells; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulins; Karyotyping; Lymphoma; Mice; Multiple Myeloma; Rabbits; Species Specificity

1971