azaguanine and Lung-Neoplasms

azaguanine has been researched along with Lung-Neoplasms* in 3 studies

Reviews

1 review(s) available for azaguanine and Lung-Neoplasms

Article	Year
Rationale of combination chemotherapy based on preclinical experiments. Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:2 Topics: Animals; Antineoplastic Agents; Azaguanine; Carcinoma; Cytarabine; Drug Synergism; Humans; Hydroxyurea; Immunotherapy; Leukemia L1210; Lung Neoplasms; Melanoma; Neoplasms; Thiosemicarbazones; Time Factors	1973

Other Studies

2 other study(ies) available for azaguanine and Lung-Neoplasms

Article	Year
[Establishment of mutant strain from human lung cancer cell (A549) with characteristics of resistance to 8-AG and HGPRT deficiency]. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 1997, Volume: 22, Issue:2 A human lung cancer cell line (A549) mutant with hypoxanthine guanine phosphoribosyltransferase (HGPRT) deficiency and resistance to 8-AG was established by treatment of the A549 cells with 3 micrograms.ml-1 N-methyl-N'-nitro-nitrosoguanidine (MNNG), and prescreened in 0.25% agarose DMEM semisolid medium containing 20 micrograms.ml-1 8-AG. The mutant cells are resistant to cytotoxic effect of 8-AG and sensitive to hypoxanthine-aminopterin thymidine (HAT) selective medium. The mutant cells can be used as a candidate parental cells to fuse with the somatic cells. Topics: Antimetabolites, Antineoplastic; Azaguanine; Cell Fusion; Cell Line, Transformed; Drug Resistance, Neoplasm; Humans; Hypoxanthine Phosphoribosyltransferase; Lung Neoplasms; Methylnitronitrosoguanidine; Mutation; Tumor Cells, Cultured	1997
New method for the isolation of drug-resistant clones of Ehrlich ascites tumor cells. Journal of the National Cancer Institute, 1974, Volume: 52, Issue:4 Topics: Animals; Azaguanine; Carcinoma, Ehrlich Tumor; Clone Cells; Drug Resistance; Guanosine; Injections, Intravenous; Lung; Lung Neoplasms; Mercaptopurine; Methods; Mice; Mice, Inbred ICR; Microspheres; Mutagens; Neoplasm Transplantation; Transplantation, Homologous	1974

Article

Year

[Establishment of mutant strain from human lung cancer cell (A549) with characteristics of resistance to 8-AG and HGPRT deficiency].

Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 1997, Volume: 22, Issue:2

A human lung cancer cell line (A549) mutant with hypoxanthine guanine phosphoribosyltransferase (HGPRT) deficiency and resistance to 8-AG was established by treatment of the A549 cells with 3 micrograms.ml-1 N-methyl-N'-nitro-nitrosoguanidine (MNNG), and prescreened in 0.25% agarose DMEM semisolid medium containing 20 micrograms.ml-1 8-AG. The mutant cells are resistant to cytotoxic effect of 8-AG and sensitive to hypoxanthine-aminopterin thymidine (HAT) selective medium. The mutant cells can be used as a candidate parental cells to fuse with the somatic cells.

Topics: Antimetabolites, Antineoplastic; Azaguanine; Cell Fusion; Cell Line, Transformed; Drug Resistance, Neoplasm; Humans; Hypoxanthine Phosphoribosyltransferase; Lung Neoplasms; Methylnitronitrosoguanidine; Mutation; Tumor Cells, Cultured

1997

New method for the isolation of drug-resistant clones of Ehrlich ascites tumor cells.

Journal of the National Cancer Institute, 1974, Volume: 52, Issue:4

Topics: Animals; Azaguanine; Carcinoma, Ehrlich Tumor; Clone Cells; Drug Resistance; Guanosine; Injections, Intravenous; Lung; Lung Neoplasms; Mercaptopurine; Methods; Mice; Mice, Inbred ICR; Microspheres; Mutagens; Neoplasm Transplantation; Transplantation, Homologous

1974