azaguanine and Leukemia--Erythroblastic--Acute

azaguanine has been researched along with Leukemia--Erythroblastic--Acute* in 2 studies

Other Studies

2 other study(ies) available for azaguanine and Leukemia--Erythroblastic--Acute

Article	Year
[Derivation of a mutant (HPRT-) cell line based on K-562 human erythromyeloleukemia]. Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:10 A mutant (HPRT-) cell line was obtained by a series of passages in the medium with 8-azaguanine on the basis of human erythromyeloleukemia K-562 cells. Rapid total death of the cells in a selective medium containing hypoxanthine, aminopterine and thymidine (3 to 4 passages) supported the deficiency as regards hypoxanthine phosphoribosyltransferase. Preliminary experiments aimed at cytotoxicity studies demonstrated that the new mutant cell line lost the property, common to the parent K-562 line, of being sensitive to the attack of natural killers. Topics: Azaguanine; Cell Line; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, Erythroblastic, Acute; Mutation	1983
Stability of the azaguanine resistant phenotype in vivo. Advances in experimental medicine and biology, 1977, Volume: 76A Topics: Adenine Phosphoribosyltransferase; Animals; Azaguanine; Cell Line; Drug Resistance; Hypoxanthine Phosphoribosyltransferase; Leukemia, Erythroblastic, Acute; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Phenotype	1977

Article

Year

[Derivation of a mutant (HPRT-) cell line based on K-562 human erythromyeloleukemia].

Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:10

A mutant (HPRT-) cell line was obtained by a series of passages in the medium with 8-azaguanine on the basis of human erythromyeloleukemia K-562 cells. Rapid total death of the cells in a selective medium containing hypoxanthine, aminopterine and thymidine (3 to 4 passages) supported the deficiency as regards hypoxanthine phosphoribosyltransferase. Preliminary experiments aimed at cytotoxicity studies demonstrated that the new mutant cell line lost the property, common to the parent K-562 line, of being sensitive to the attack of natural killers.

Topics: Azaguanine; Cell Line; Humans; Hypoxanthine Phosphoribosyltransferase; Leukemia, Erythroblastic, Acute; Mutation

1983

Stability of the azaguanine resistant phenotype in vivo.

Advances in experimental medicine and biology, 1977, Volume: 76A

Topics: Adenine Phosphoribosyltransferase; Animals; Azaguanine; Cell Line; Drug Resistance; Hypoxanthine Phosphoribosyltransferase; Leukemia, Erythroblastic, Acute; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Phenotype

1977