azadiradione has been researched along with Edema* in 1 studies
1 other study(ies) available for azadiradione and Edema
Article | Year |
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Anti-nociceptive and anti-inflammatory activities of Azadirachta indica fruit skin extract and its isolated constituent azadiradione.
This study was carried out to evaluate the anti-nociceptive and anti-inflammatory activities of carbon tetrachloride extract (CTCE) of Azadirachta indica fruit skin and its isolated constituent azadiradione at two different dose levels (50 and 100 mg kg⁻¹ body weight). Anti-nociceptive screening by writhing test and hot-plate technique supported both peripheral and central mechanisms, respectively. Anti-inflammatory activity was observed using carrageenan-induced paw oedema model. The results concluded that the animals treated with 100 mg kg⁻¹ dose of CTCE and azadiradione exhibited significant anti-nociceptive and anti-inflammatory activities. This study had rationalised the ethnomedicinal use of the plant for wound, burns and injury by tribal people. Topics: Animals; Anti-Inflammatory Agents; Azadirachta; Carbon Tetrachloride; Carrageenan; Edema; Fruit; Limonins; Mice; Plant Extracts | 2013 |