Compounds > azacitidine

azacitidine and Thyroid Neoplasms

azacitidine has been researched along with Thyroid Neoplasms in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's2 (7.41)18.2507
2000's11 (40.74)29.6817
2010's12 (44.44)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Albulescu, A; Anton, G; Badiu, CV; Bostan, M; Botezatu, A; Dobrescu, R; Fudulu, A; Grancea, C; Huica, I; Iancu, IV; Manda, DA; Mihaila, M; Plesa, A; Vladoiu, SV1
Borghi, MO; Cantone, MC; Caraglia, M; Di Blasio, AM; Dicitore, A; Gaudenzi, G; Gelmini, G; Gentilini, D; Grassi, ES; Hofland, LJ; Misso, G; Pepe, D; Persani, L; Vitale, G1
Cao, YM; Gu, J; Ji, QH; Liao, T; Qu, N; Shi, RL; Sun, GH; Wang, Y; Wang, YJ; Wei, WJ; Wen, D; Yu, J; Zhang, L; Zhang, YS; Zhao, YX; Zhu, YX1
Frasca, F; Manzella, L; Massimino, M; Pennisi, MS; Puma, A; Romano, C; Sciacca, L; Stella, S; Tirrò, E; Vella, V; Vitale, SR1
Bernasconi, MJ; Cogdill, AP; Gunda, V; Parangi, S; Wargo, JA1
Camargo, RY; Cerutti, JM; Friguglietti, CU; Galrão, AL; Medeiros-Neto, G; Moraes, L; Rubio, IG; Serrano-Nascimento, C; Suzuki, MF1
Bernasconi, MJ; Frederick, DT; Gunda, V; Parangi, S; Wargo, JA1
Huang, H; Huang, Z; Lin, J; Lin, X; Qiu, J; Shi, B; Wang, C; Wei, X; Wu, W; Zhang, L1
Agate, L; Capodanno, A; Ciampi, R; Collecchi, P; Elisei, R; Miasaki, FY; Pinchera, A; Vivaldi, A2
Katoh, R; Kawasaki, T; Kobayashi, M; Kondo, T; Ma, D; Mochizuki, K; Nakamura, N; Nakazawa, T; Niu, D; Yamane, T1
Clark, OH; Duh, QY; Griff, NJ; Grogan, RH; Kebebew, E; Mitmaker, EJ; Sarkar, R; Shen, WT1
Dong, X; Korch, C; Meinkoth, JL1
Hayashi, Y; Imai, T; Kikumori, T; Kiuchi, T; Kurebayashi, J; Murata, Y; Sassa, M; Watanabe, R1
Andry, G; De Martelar, V; Dom, G; Dumont, JE; Galdo, VC; Hébrant, A; Leteurtre, E; Libert, F; Maenhaut, C; Tarabichi, M; Tomás, G; van Staveren, WC1
Byun, DW; Chun, SW; Jung, CH; Kang, SG; Kim, BY; Kim, CH; Kim, SJ; Kim, YJ; Ko, HJ; Mok, JO; Park, HK; Suh, KI; Yoo, MH1
de la Chapelle, A; Huang, Y; Pellegata, NS1
Akiyama, Y; Endo, S; Fujisawa, K; Higuchi, T; Maesawa, C; Masuda, T; Ogasawara, S; Saito, K; Sato, N; Tomisawa, Y; Wada, K; Yamamoto, M1
Aldred, MA; Broelsch, CE; Eng, C; Frilling, A; Morrison, CD; Plass, C; Waite, KA; Weber, F1
Domann, FE; Howe, JR; Lal, G; Nicholson, RM; O'Dorisio, MS; Padmanabha, L; Smith, BJ1
Ain, KB; Li, W; Venkataraman, GM1
Aydin, D; Doğan, AL; Güç, D; Taşbasan, B; Tazebay, UH; Tuncel, M; Uğur, O; Yaman, E2
Domann, FE; Fitzgerald, MP; Krager, K; Provenzano, MJ1
Ain, KB; Marcinek, R; Venkataraman, GM; Yatin, M1
Thomas, GA; Williams, ED1
Bruntsch, U; Gallmeier, WM; Osieka, R; Schmidt, CG; Seeber, S1

Other Studies

27 other study(ies) available for azacitidine and Thyroid Neoplasms

ArticleYear
Alterations of regulatory factors and DNA methylation pattern in thyroid cancer.
    Cancer biomarkers : section A of Disease markers, 2020, Volume: 28, Issue:2

    Topics: Adenocarcinoma, Follicular; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Azacitidine; Biomarkers, Tumor; Carcinogenesis; Cell Line, Tumor; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Epigenesis, Genetic; Feasibility Studies; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Mixed Function Oxygenases; Promoter Regions, Genetic; Proto-Oncogene Proteins; Sensitivity and Specificity; Thyroid Cancer, Papillary; Thyroid Gland; Thyroid Neoplasms; Young Adult

2020
Synergistic activity of everolimus and 5-aza-2'-deoxycytidine in medullary thyroid carcinoma cell lines.
    Molecular oncology, 2017, Volume: 11, Issue:8

    Topics: Azacitidine; Carcinoma, Neuroendocrine; Decitabine; Drug Synergism; Everolimus; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Humans; Neoplasm Proteins; Thyroid Neoplasms

2017
Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation.
    Oncology reports, 2018, Volume: 39, Issue:1

    Topics: Apoptosis; Azacitidine; Carcinoma, Papillary; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Male; Mutation; Neoplasm Invasiveness; Neoplasm Staging; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Thyroid Cancer, Papillary; Thyroid Neoplasms; Transcription Factors

2018
Effect of Combined Epigenetic Treatments and Ectopic NIS Expression on Undifferentiated Thyroid Cancer Cells.
    Anticancer research, 2018, Volume: 38, Issue:12

    Topics: Animals; Azacitidine; Cells, Cultured; Combined Modality Therapy; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genetic Therapy; Humans; Rats; Rats, Inbred F344; Symporters; Thyroid Neoplasms; Transfection; Valproic Acid

2018
Potential role of 5-aza-2'-deoxycytidine induced MAGE-A4 expression in immunotherapy for anaplastic thyroid cancer.
    Surgery, 2013, Volume: 154, Issue:6

    Topics: Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Gene Expression; Humans; Immunotherapy; Indoles; MAP Kinase Signaling System; Melanoma; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins B-raf; Sulfonamides; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms

2013
Hypermethylation of a New Distal Sodium/Iodide Symporter (NIS) enhancer (NDE) is associated with reduced NIS expression in thyroid tumors.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:6

    Topics: Azacitidine; Carcinoma, Papillary, Follicular; CpG Islands; DNA Methylation; Down-Regulation; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Symporters; Thyroid Neoplasms

2014
A potential role for immunotherapy in thyroid cancer by enhancing NY-ESO-1 cancer antigen expression.
    Thyroid : official journal of the American Thyroid Association, 2014, Volume: 24, Issue:8

    Topics: Animals; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Coculture Techniques; Cytoplasm; Decitabine; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Granzymes; Humans; Immunotherapy; Interferon-gamma; Lymphocytes; Membrane Proteins; Methylation; Mice; Mice, SCID; Neoplasm Metastasis; Polymerase Chain Reaction; Receptors, Antigen, T-Cell; RNA, Messenger; Thyroid Neoplasms

2014
Hypermethylation of the HIC1 promoter and aberrant expression of HIC1/SIRT1 contribute to the development of thyroid papillary carcinoma.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Adult; Apoptosis; Azacitidine; Carcinoma, Papillary; Cell Cycle Checkpoints; Cell Proliferation; Cellular Senescence; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Transcription Factors; Male; Middle Aged; Promoter Regions, Genetic; Sirtuin 1; Thyroid Neoplasms

2016
Retinoic acid receptor beta2 re-expression and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment.
    Journal of endocrinological investigation, 2008, Volume: 31, Issue:8

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Organ Specificity; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Thyroid Gland; Thyroid Neoplasms; Transfection

2008
Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas.
    Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:7

    Topics: Azacitidine; Base Sequence; Carcinoma, Papillary; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; DNA Primers; Epigenesis, Genetic; Gene Expression Profiling; Gene Silencing; Histones; Humans; Hydroxamic Acids; Nuclear Proteins; RNA, Messenger; RNA, Neoplasm; Thyroid Gland; Thyroid Neoplasms; Thyroid Nuclear Factor 1; Transcription Factors

2009
Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid.
    Molecular and cellular endocrinology, 2009, Aug-13, Volume: 307, Issue:1-2

    Topics: Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Decitabine; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Organ Specificity; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Symporters; Thyroid Neoplasms; Tretinoin

2009
Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitors.
    Surgery, 2011, Volume: 149, Issue:4

    Topics: Adenocarcinoma, Follicular; Adenocarcinoma, Papillary; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Thyroid Neoplasms; Valproic Acid

2011
Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells.
    Endocrine-related cancer, 2011, Volume: 18, Issue:3

    Topics: Adenocarcinoma, Follicular; Azacitidine; Butyrates; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Screening Assays, Antitumor; Drug Synergism; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Neoplasm Proteins; rap GTP-Binding Proteins; rap1 GTP-Binding Proteins; RNA, Small Interfering; Thyroid Neoplasms; Up-Regulation

2011
Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:5

    Topics: Adult; Aged; Apoptosis Regulatory Proteins; Azacitidine; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Thyroid Cancer, Papillary; Thyroid Neoplasms; Trans-Activators; Transcription Factors

2011
5-aza-2'-deoxycytidine has minor effects on differentiation in human thyroid cancer cell lines, but modulates genes that are involved in adaptation in vitro.
    Thyroid : official journal of the American Thyroid Association, 2013, Volume: 23, Issue:3

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Carcinoma; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Survival; Decitabine; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Oligonucleotide Array Sequence Analysis; Thyroid Gland; Thyroid Neoplasms; Vorinostat

2013
DNA methylation of RUNX3 in papillary thyroid cancer.
    The Korean journal of internal medicine, 2012, Volume: 27, Issue:4

    Topics: Azacitidine; Biomarkers, Tumor; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; Gene Expression; Humans; Thyroid Cancer, Papillary; Thyroid Neoplasms

2012
Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma.
    International journal of cancer, 2003, May-10, Volume: 104, Issue:6

    Topics: Adenocarcinoma, Papillary; Adult; Aged; Azacitidine; Base Sequence; CpG Islands; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Loss of Heterozygosity; Male; Metallothionein; Microsatellite Repeats; Middle Aged; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Thyroid Neoplasms; Tumor Cells, Cultured

2003
Disruption of cell-type-specific methylation at the Maspin gene promoter is frequently involved in undifferentiated thyroid cancers.
    Oncogene, 2004, Feb-05, Volume: 23, Issue:5

    Topics: Adenoma; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Promoter Regions, Genetic; Proteins; RNA, Messenger; Serpins; Thyroid Gland; Thyroid Neoplasms

2004
Silencing of the maternally imprinted tumor suppressor ARHI contributes to follicular thyroid carcinogenesis.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:2

    Topics: Adenocarcinoma, Follicular; Adenoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Decitabine; DNA Primers; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Genomic Imprinting; Humans; Loss of Heterozygosity; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; Thyroid Neoplasms

2005
RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma.
    Cancer, 2006, Dec-15, Volume: 107, Issue:12

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; Thyroid Neoplasms; Transcription Factors

2006
Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:3

    Topics: Adenoma; Azacitidine; Butyrates; Cell Line, Tumor; Cycloheximide; Deoxyribonuclease I; Drug Synergism; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Symporters; Thyroid Neoplasms; Transfection

2007
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake.
    Cancer biotherapy & radiopharmaceuticals, 2007, Volume: 22, Issue:2

    Topics: Aged; Apoptosis; Azacitidine; Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Iodine Radioisotopes; Proteins; RNA, Messenger; Thyroid Gland; Thyroid Neoplasms; Time Factors; Tretinoin

2007
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake.
    Cancer biotherapy & radiopharmaceuticals, 2007, Volume: 22, Issue:3

    Topics: Aged; Apoptosis; Azacitidine; Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Iodine Radioisotopes; Proteins; RNA, Messenger; Thyroid Gland; Thyroid Neoplasms; Time Factors; Tretinoin

2007
Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2007, Volume: 137, Issue:5

    Topics: Acetylation; Azacitidine; Blotting, Western; Butyrates; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Therapy, Combination; Epigenesis, Genetic; Humans; Iodine Radioisotopes; Polymerase Chain Reaction; RNA, Messenger; Sodium Iodide; Symporters; Thyroid Neoplasms

2007
Restoration of iodide uptake in dedifferentiated thyroid carcinoma: relationship to human Na+/I-symporter gene methylation status.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:7

    Topics: Adenoma; Antimetabolites, Antineoplastic; Azacitidine; Butyrates; Carcinoma, Papillary; Carrier Proteins; DNA; DNA Methylation; Gene Expression; Humans; Iodides; Membrane Proteins; Promoter Regions, Genetic; RNA, Messenger; Symporters; Thyroid Neoplasms; Transcription, Genetic; Tumor Cells, Cultured

1999
Production of thyroid tumours in mice by demethylating agents.
    Carcinogenesis, 1992, Volume: 13, Issue:6

    Topics: Animals; Azacitidine; Decitabine; DNA; Goiter; Methylation; Mice; Thyroid Neoplasms

1992
[New cytostatics in oncological therapy].
    Deutsche medizinische Wochenschrift (1946), 1974, Nov-29, Volume: 99, Issue:48

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Chemical Phenomena; Chemistry; DNA Replication; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Lymphoma; Male; Mitolactol; Neoplasms; Nitrosourea Compounds; Testicular Neoplasms; Thyroid Neoplasms

1974