azacitidine and Thalassemias

azacitidine has been researched along with Thalassemias in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199025 (80.65)18.7374
1990's3 (9.68)18.2507
2000's3 (9.68)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Datta, S1
Lal, A; Vichinsky, E1
Atweh, GF; Fathallah, H; Sutton, M1
Anagnou, NP; DeSimone, J; Humphries, RK; Keller, GH; Keller, P; Ley, TJ; Nienhuis, AW; Turner, PH; Young, NS1
Benz, EJ2
Kolata, G1
Orkin, SH1
Anagnou, NP; DeSimone, J; Heller, P; Ley, TJ; Nienhuis, AW; Young, NS1
Bodmer, WF; Clegg, JB; Weatherall, DJ1
DeSimone, J; Heller, P; Ley, TJ; Nienhuis, AW; Noguchi, CT; Schechter, AN; Turner, PH1
Kuratowska, Z1
Cypress, GC; Nalbandian, RM1
Adamson, JW1
DeSimone, J; Heller, P1
Steinberg, MH1
Craig, JE; Rochette, J; Thein, SL1
Nienhuis, AW; Stamatoyannopoulos, JA1
Fujita, S1
Dover, G; Humphries, RK; Ley, TJ; Nienhuis, AW; Young, NS1
Boyer, SH; Charache, S; Dover, GJ; Nora, R1
Anderson, WF; Berg, P; Eglitis, M; Goldberg, S; Humphries, RK; Kantoff, P1
Karlsson, S; Nienhuis, AW1
Platt, OS1
Dunbar, C; Kan, YW; Nienhuis, A; Travis, W1
Rokicka-Piotrowicz, M1
Ley, TJ; Macher, AM; Nienhuis, AW; Sands, JM1
Jones, PA1
Charache, S; Dover, G; Humphries, RK; Ley, T; Moore, JG; Nienhuis, AW; Young, NS1
Ley, TJ; Nienhuis, AW1

Reviews

10 review(s) available for azacitidine and Thalassemias

ArticleYear
The role of fetal hemoglobin-enhancing agents in thalassemia.
    Seminars in hematology, 2004, Volume: 41, Issue:4 Suppl 6

    Topics: Azacitidine; Decitabine; Fetal Hemoglobin; Humans; Thalassemia; Treatment Outcome

2004
Pharmacological induction of fetal hemoglobin: Why haven't we been more successful in thalassemia?
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Combined Modality Therapy; Drug Approval; Drug Evaluation; Drug Evaluation, Preclinical; Erythropoiesis; Fetal Hemoglobin; Gene Expression; Gene Expression Regulation; Globins; Humans; Hydroxyurea; Iron; K562 Cells; Models, Animal; Papio; Thalassemia; Transfusion Reaction; United States; United States Food and Drug Administration

2005
5-Azacytidine and fetal hemoglobin.
    American journal of hematology, 1984, Volume: 17, Issue:4

    Topics: Adult; Anemia, Sickle Cell; Animals; Azacitidine; Carcinogens; Disease Models, Animal; DNA; Fetal Hemoglobin; Gene Expression Regulation; Humans; Male; Methylation; Middle Aged; Papio; Thalassemia

1984
Review: the sickle hemoglobinopathies--genetic analyses of common phenocopies and new molecular approaches to treatment.
    The American journal of the medical sciences, 1984, Volume: 288, Issue:4

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Fetal Hemoglobin; Gene Expression Regulation; Genotype; Globins; Hemoglobin A; Hemoglobin A2; Hemoglobin SC Disease; Hemoglobin, Sickle; Humans; Phenotype; Sickle Cell Trait; Thalassemia

1984
Fetal hemoglobin levels in adults.
    Blood reviews, 1994, Volume: 8, Issue:4

    Topics: Adult; Azacitidine; Base Sequence; Butyrates; Butyric Acid; Fetal Hemoglobin; Gene Expression Regulation; Genetic Therapy; Globins; Humans; Hydroxyurea; Molecular Sequence Data; Sequence Deletion; Thalassemia

1994
Therapeutic approaches to hemoglobin switching in treatment of hemoglobinopathies.
    Annual review of medicine, 1992, Volume: 43

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Hemoglobinopathies; Humans; Hydroxyurea; Thalassemia

1992
Developmental regulation of human globin genes.
    Annual review of biochemistry, 1985, Volume: 54

    Topics: Azacitidine; Chromatin; Chromosome Deletion; Chromosomes, Human, 16-18; Chromosomes, Human, 6-12 and X; Enhancer Elements, Genetic; Fetal Hemoglobin; Gene Expression Regulation; Genes; Globins; Hemoglobins; Humans; Methylation; Mutation; Poly A; Promoter Regions, Genetic; Protein Biosynthesis; Repetitive Sequences, Nucleic Acid; RNA Caps; RNA Processing, Post-Transcriptional; RNA, Messenger; Thalassemia; Transcription Factors

1985
[Fetal hemoglobin].
    Postepy higieny i medycyny doswiadczalnej, 1989, Volume: 43, Issue:5-6

    Topics: Amino Acid Sequence; Amino Acids; Anemia, Sickle Cell; Azacitidine; Fetal Blood; Fetal Hemoglobin; Humans; Molecular Sequence Data; Stimulation, Chemical; Thalassemia

1989
Altering gene expression with 5-azacytidine.
    Cell, 1985, Volume: 40, Issue:3

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Cell Differentiation; Cell Line; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Fetal Hemoglobin; Gene Expression Regulation; Genes; Genes, Regulator; Methylation; Mutation; Neoplasms; Thalassemia; Thymidine Kinase

1985
Induction of hemoglobin F synthesis in patients with beta thalassemia.
    Annual review of medicine, 1985, Volume: 36

    Topics: Animals; Azacitidine; DNA; Erythroblasts; Female; Fetal Hemoglobin; Gene Expression Regulation; Globins; Humans; Hydroxyurea; Methylation; Papio; Thalassemia

1985

Trials

2 trial(s) available for azacitidine and Thalassemias

ArticleYear
Molecular genetics of the sickling syndromes: evolution of new strategies for improved diagnosis.
    The American journal of pediatric hematology/oncology, 1984,Spring, Volume: 6, Issue:1

    Topics: Anemia, Sickle Cell; Azacitidine; Base Composition; Chromosome Mapping; Clinical Trials as Topic; DNA Restriction Enzymes; DNA, Recombinant; Gene Expression Regulation; Genes; Globins; Hemoglobin SC Disease; Humans; Prenatal Diagnosis; Thalassemia

1984
Progress toward increasing fetal hemoglobin production in man: experience with 5-azacytidine and hydroxyurea.
    Annals of the New York Academy of Sciences, 1985, Volume: 445

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Bone Marrow; Cells, Cultured; Clinical Trials as Topic; Erythropoiesis; Fetal Hemoglobin; Humans; Hydroxyurea; Reticulocytes; Thalassemia

1985

Other Studies

19 other study(ies) available for azacitidine and Thalassemias

ArticleYear
Treatment of thalassoemia--the current scenario.
    Journal of the Indian Medical Association, 2002, Volume: 100, Issue:2

    Topics: Azacitidine; Bone Marrow Transplantation; Deferiprone; Fetal Hemoglobin; Genetic Therapy; Humans; Hydroxyurea; Iron Chelating Agents; Pyridones; Thalassemia

2002
5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia.
    The New England journal of medicine, 1982, Dec-09, Volume: 307, Issue:24

    Topics: Adult; Azacitidine; DNA; Erythropoiesis; Gene Expression Regulation; Globins; Hemoglobins; Humans; Male; Methylation; RNA, Messenger; Stimulation, Chemical; Thalassemia

1982
Clinical management of gene expression.
    The New England journal of medicine, 1982, Dec-09, Volume: 307, Issue:24

    Topics: Azacitidine; DNA; Fetal Hemoglobin; Gene Expression Regulation; Globins; Humans; Methylation; Thalassemia

1982
Fetal hemoglobin genes turned on in adults.
    Science (New York, N.Y.), 1982, Dec-24, Volume: 218, Issue:4579

    Topics: Adult; Anemia, Sickle Cell; Azacitidine; Fetal Hemoglobin; Hemoglobin, Sickle; Humans; Male; Thalassemia

1982
5-azacytidine for beta-thalassaemia?
    Lancet (London, England), 1983, Jan-01, Volume: 1, Issue:8314-5

    Topics: Animals; Azacitidine; Fetal Hemoglobin; Gene Expression Regulation; Humans; Thalassemia

1983
Controlling the fetal globin switch in man.
    Nature, 1983, Jan-13, Volume: 301, Issue:5896

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Fetal Hemoglobin; Gene Expression Regulation; Humans; Papio; Thalassemia

1983
5-azacytidine for beta thalassaemia?
    Lancet (London, England), 1983, Feb-26, Volume: 1, Issue:8322

    Topics: Azacitidine; Ethics, Medical; Fetal Hemoglobin; Humans; Risk Assessment; Thalassemia; Therapeutic Human Experimentation

1983
5-azacytidine for beta-thalassemia?
    Lancet (London, England), 1983, Mar-05, Volume: 1, Issue:8323

    Topics: Azacitidine; Child; Ethics, Medical; Human Experimentation; Humans; Thalassemia

1983
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia.
    Blood, 1983, Volume: 62, Issue:2

    Topics: Adult; Anemia, Sickle Cell; Azacitidine; Bone Marrow Cells; DNA; Erythrocytes; Fetal Hemoglobin; Globins; Humans; Male; Methylation; Middle Aged; RNA, Messenger; Thalassemia

1983
[Pharmacological correction of genetic defects - azacytidine in the treatment of thalassemia].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Jun-13, Volume: 38, Issue:24

    Topics: Azacitidine; Fetal Hemoglobin; Gene Expression Regulation; Humans; Thalassemia

1983
Gene switching -- a new therapeutic epoch: discussion paper.
    Journal of the Royal Society of Medicine, 1984, Volume: 77, Issue:3

    Topics: Anemia, Sickle Cell; Azacitidine; Female; Fetal Blood; Fetal Hemoglobin; Gene Expression Regulation; Genes; Hemoglobins; Humans; Operon; Pregnancy; Thalassemia

1984
Hemoglobin--from F to A, and back.
    The New England journal of medicine, 1984, Apr-05, Volume: 310, Issue:14

    Topics: Anemia, Sickle Cell; Azacitidine; DNA; Fetal Hemoglobin; Humans; Hydroxyurea; Methylation; Thalassemia

1984
[Congenital hemoglobin abnormalities--thalassemia syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:3

    Topics: Animals; Azacitidine; Blood Transfusion; Hemoglobins; Humans; Thalassemia

1991
Pharmacological manipulation of fetal hemoglobin synthesis in patients with severe beta-thalassemia.
    Annals of the New York Academy of Sciences, 1985, Volume: 445

    Topics: Azacitidine; Fetal Hemoglobin; Globins; Humans; Hydroxyurea; Iron; Kinetics; RNA; Thalassemia; Time Factors

1985
Attempts at gene therapy in beta-thalassemic mice.
    Annals of the New York Academy of Sciences, 1985, Volume: 445

    Topics: Animals; Azacitidine; Base Sequence; DNA, Recombinant; DNA, Viral; Genetic Engineering; Genetic Vectors; Globins; Mice; Mice, Mutant Strains; Microinjections; Pedigree; Retroviridae; Thalassemia

1985
Chemotherapy to increase fetal hemoglobin in patients with sickle cell anemia.
    The American journal of pediatric hematology/oncology, 1985,Fall, Volume: 7, Issue:3

    Topics: Anemia, Sickle Cell; Azacitidine; Cytarabine; Fetal Hemoglobin; Humans; Hydroxyurea; Kinetics; Thalassemia

1985
5-Azacytidine treatment in a beta (0)-thalassaemic patient unable to be transfused due to multiple alloantibodies.
    British journal of haematology, 1989, Volume: 72, Issue:3

    Topics: Adult; Azacitidine; Humans; Isoantibodies; Male; Thalassemia

1989
Disseminated infection caused by Cunninghamella bertholletiae in a patient with beta-thalassemia. Case report and review of the literature.
    Annals of internal medicine, 1985, Volume: 102, Issue:1

    Topics: Adult; Azacitidine; Chronic Disease; Diagnosis, Differential; Entomophthora; Hematopoiesis; Humans; Immune Tolerance; Male; Mucormycosis; Mycoses; Splenectomy; Thalassemia

1985
5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:2

    Topics: Adult; Anemia, Sickle Cell; Azacitidine; Erythrocytes; Erythropoiesis; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Middle Aged; RNA, Messenger; Thalassemia

1985