azacitidine has been researched along with Stomach Neoplasms in 147 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (1.36) | 18.2507 |
| 2000's | 62 (42.18) | 29.6817 |
| 2010's | 77 (52.38) | 24.3611 |
| 2020's | 6 (4.08) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z; Fan, D; Kang, X; Liu, H; Nie, Y; Yang, Y; Zhang, L | 1 |
| Chang, X; Chen, S; Dai, D; Deng, P; Wang, J; Xu, X; Xu, Y; Zhang, C; Zhu, X | 1 |
| Anauate, AC; Arasaki, CH; Arruda Cardoso Smith, M; Artigiani, R; Assumpção, PP; Burbano, RR; Calcagno, DQ; Chen, ES; Demachki, S; Geraldis, JC; Gigek, CO; Krainer, J; Leal, MF; Lourenço, LG; Pabinger, S; Payão, SLM; Rasmussen, LT; Santos, LC; Wisnieski, F | 1 |
| Hosseinpourfeizi, MA; Moaddab, Y; Rezaei, S; Safaralizadeh, R | 1 |
| An, X; Cai, W; Guo, C; Li, M; Miao, W; Wang, B; Wei, J; Zhang, C; Zhang, F | 1 |
| Munakata, S; Nohara, S; Tomimatsu, H; Uji, R; Yasumura, Y; Yuzawa, H | 1 |
| Liu, J; Liu, W; Luo, B; Wang, J; Zhao, Z | 1 |
| Iizasa, H; Nakamura, M; Nishikawa, J; Saito, M; Sakai, K; Sakaida, I; Sasaki, S; Shimokuri, K; Suehiro, Y; Yamasaki, T; Yanagihara, M; Yoshiyama, H | 1 |
| Cao, C; Chen, Z; Jiang, Q; Lv, Y; Qian, X; Song, Y; Wang, S; Zuo, Y | 1 |
| Lei, C; Li, T; Ni, Z; Shi, Y; Wu, Q; Zhu, F | 1 |
| Dang, C; Song, Y; Wang, W; Xie, X; Zhang, H; Zhou, Z | 1 |
| He, X; Li, S; Pei, L; Ren, G; Sun, R; Xiang, Q; Xiang, T | 1 |
| Han, SR; Kang, YH; Kim, JT; Kim, TW; Lee, HG; Lee, MS; Lee, SH; Yoo, SM | 1 |
| Kang, GH; Park, SY; Shin, SH | 1 |
| Feng, YF; Qu, CJ; Song, Y; Tian, Y; Tu, JC; Zuo, Y | 1 |
| Peek, RM; Schneider, BG | 1 |
| Mori, A; Niwa, T; Tatematsu, M; Toyoda, T; Tsukamoto, T; Ushijima, T | 1 |
| Choi, YH; Kim, GY; Kim, WJ; Shin, DY; Sung Kang, H; Yoo, YH | 1 |
| Akiyama, Y; Hashimoto, Y; Yuasa, Y | 1 |
| Hinoda, Y; Morishige, A; Nakamura, M; Nishikawa, J; Oga, A; Okada, T; Saito, M; Sakai, K; Sakaida, I; Sasaki, K; Suehiro, Y; Zhang, Y | 1 |
| Guo, LH; He, JS; Li, H; Wang, F; Yu, J | 1 |
| Drews, M; Frycz, BA; Jagodziński, PP; Marciniak, R; Murawa, D; Murawa, P; Wysocki-Borejsza, M | 1 |
| Chun, KH; Hwang, JA; Kim, SJ; Lee, YS; Ro, JY | 1 |
| Bai, R; Feng, G; Song, M; Yuan, H; Zhang, J; Zhang, Y; Zheng, J | 1 |
| Cheng, Y; Dang, C; Diao, D; Guo, Q; Liu, D; Song, Y; Wang, W; Wu, X; Xia, P; Zhang, H | 1 |
| Li, Q; Ling, X; Ling, Y; Shi, X; Wang, Y | 1 |
| Dong, L; Lei, H; Li, Z; Liu, C; Luo, M; Ma, Y; Shen, J; Song, W; Wang, F; Wang, Y; Yu, J; Zhang, J | 1 |
| Blanchard, TG; Czinn, SJ; Guang, W; Kim, KC; Lillehoj, EP | 1 |
| Li, B; Li, Y; Lu, Z; Luo, H; Wang, Y; Wu, X; Xu, Z; Zhang, Z | 1 |
| Fan, D; Nie, Y; Shi, Y; Wu, K; Wu, Q; Xia, L; Yang, Z | 1 |
| Cao, Y; Chen, H; Jiang, M; Jie, Z; Le, Z; Li, D; Li, Z; Liu, Y; Tan, S; Xiong, J; Zhang, G | 1 |
| Bak, YT; Choe, J; Joo, MK; Kim, HJ; Kim, JS; Kim, KH; Lee, BJ; Park, JJ; Yoo, HS | 1 |
| Cho, SG; Dong, SM; Hayward, SD; Kim, H; Kwon, HJ; Kwon, SH; Lee, HG; Lee, JH; Lee, JM; Park, JH; Park, PG; Yoon, H | 1 |
| Cui, FB; Ding, H; Li, RT; Liu, BR; Liu, Q; Qian, XP; Wang, HY; Wu, FL; Wu, PY; Yang, M; Yu, LX; Yue, GF | 1 |
| Han, L; Jiang, K; Kang, C; Liu, X; Ning, X; Shi, Z; Zhang, A; Zhang, Q | 1 |
| Chen, J; Dai, D; Xu, X; Zhang, C; Zhu, X | 1 |
| Bu, JY; Cui, RJ; Du, YD; Huang, N; Li, D; Lin, P; Sun, H; Tang, JB; Xu, CY; Yang, ZK; Yu, XG | 1 |
| Goto, K; Honma, R; Ishikawa, S; Matsubara, A; Oue, N; Sakamoto, N; Sentani, K; Tanimoto, K; Teishima, J; Yasui, W | 1 |
| Che, K; Li, J; Liu, M; Liu, X; Luo, B | 1 |
| Hashimoto, S; Nakamura, M; Nishikawa, J; Okamoto, T; Saito, M; Sakai, K; Sakaida, I; Sasaki, S; Suehiro, Y; Yamasaki, T | 1 |
| Chen, J; Dai, D; Jin, J; Li, X; Zhang, C; Zhang, H; Zhang, J | 1 |
| Cai, HL; Huang, HQ; Huang, ZJ; Li, GP; Liu, G; Luo, Q; Wei, B | 1 |
| Chen, Y; Fang, J; Lu, R; Sun, D; Toan, X; Wang, X; Zhang, Y | 1 |
| Dai, DQ; Wang, JF | 2 |
| Choi, CH; Kim, KJ; Lee, TB; Min, YD; Park, JH | 1 |
| Cho, JS; Hahn, Y; Jang, HR; Jeong, HY; Kim, HM; Kim, JH; Kim, M; Kim, YS; Lee, CW; Noh, SM; Song, KS; Yeom, YI; Yoo, HS | 1 |
| Kim, J; Kim, WH; Lee, SH; Lee, YM | 1 |
| Hirakawa, K; Matsuzaki, T; Qiu, H; Shinto, O; Yashiro, M | 1 |
| Meng, CF; Peng, G; Zhu, XJ | 1 |
| Dai, DQ; Liu, HB; Shen, WJ; Teng, Y | 2 |
| Hou, K; Hu, X; Jing, W; Liu, Y; Qu, X; Teng, Y; Yang, X; Zhang, J; Zhang, Y | 1 |
| Hibi, T; Kanai, Y; Matsuzaki, J; Nakagawa, I; Saito, Y; Suzuki, H; Tsugawa, H | 1 |
| Ganesan, A; Haglund, C; Hemmes, A; Junnila, S; Kokkola, A; Monni, O; Mrena, J; Nykänen, A; Petrova, TV; Ristimäki, A; Tai, HH; Thiel, A | 1 |
| Dai, DQ; Meng, CF; Peng, G; Zhu, XJ | 4 |
| Gyobu, K; Hosoya, K; Takeshima, H; Ushijima, T; Yamashita, S | 1 |
| Chi, SG; Kang, MJ; Kim, YH; Park, HC; Son, MS | 1 |
| Abraham, JM; Agarwal, R; Cheng, Y; David, S; Hamilton, JP; Jin, Z; Meltzer, SJ; Montgomery, E; Mori, Y; Morin, PJ; Olaru, AV; Selaru, FM; Yang, J | 1 |
| Akiyama, Y; Hashimoto, Y; Otsubo, T; Shimada, S; Yuasa, Y | 1 |
| Dong, Z; Du, J; Feng, Y; Huang, B; Lu, J; Matloob, AF; Pan, H; Pan, L; Zhao, J; Zhong, Y | 1 |
| Chang, YS; Chen, LC; Leu, YW; Li, HP; Lin, KH; Liu, HP; Lu, CY; Lu, YJ; Wang, CS; Wu, CS | 1 |
| Dohi, O; Mitsufuji, S; Sakakura, C; Takada, H; Taniwaki, M; Wakabayashi, N; Yasui, K; Yoshikawa, T | 1 |
| Cen, JN; Chen, W; Gao, N; Shen, Y | 1 |
| Akashi, H; Imai, K; Itoh, F; Kai, M; Kamimae, S; Maruyama, R; Nojima, M; Sasaki, Y; Shinomura, Y; Sugai, T; Suzuki, H; Tokino, T; Toyota, M; Watanabe, Y; Yamamoto, E; Yamano, H; Yamashita, M | 1 |
| Du, H; Ge, SH; Hu, Y; Ji, JF; Li, JY; Liu, N; Liu, YQ; Lu, AP; Niu, ZJ; Peng, Y; Wang, XH; Xing, XF; Zhang, GG; Zhang, LH; Zhao, W; Zhong, XY; Zhu, YB | 1 |
| Chen, MH; Chen, WJ; Hung, IF; Lam, CS; Lan, HY; Ma, J; Pang, R; Tan, VP; Wang, JD; Wang, QY; Wong, BC; Zhang, WJ; Zou, B | 1 |
| Fang, WL; Hu, LY; Kao, HW; Lai, CH; Li, SC; Lin, WC; Tsai, KW; Wu, CW | 1 |
| El-Rifai, W; Hu, T; Jackson, K; Marshal, D; Peng, D; Soutto, M | 1 |
| Guo, X; Jing, C; Li, C; Li, L; Liu, J; Shi, Y; Wang, J; Zhang, L | 1 |
| Gong, Y; Guo, MZ; Yang, YS; Ye, ZJ; Zhang, XL; Zhao, YL | 1 |
| Hashiguchi, K; Hiraki, M; Kai, K; Kitajima, Y; Miyazaki, K; Nakamura, J; Noshiro, H | 1 |
| Becker, K; Hapfelmeier, A; Höfler, H; Keller, G; Langer, R; Mutze, K; Novotny, A; Ott, K; Schumacher, F | 1 |
| Chen, J; Fan, H; Gu, D; Huang, H; Qiao, F; Su, X; Wei, X; Xu, Z | 1 |
| Jiang, P; Lee, W; Li, W; Xiang, Y; Yu, G; Zhang, Y | 1 |
| Chan, WC; Fang, WL; Hu, LY; Huang, KH; Kao, HW; Lai, CH; Li, SC; Liao, YL; Lin, WC; Tsai, KW; Wu, CW | 1 |
| Chang, X; Chen, J; Dai, D; Ma, J; Zhang, S; Zhi, Y | 1 |
| Hiraishi, T; Itoh, F; Maehata, T; Niwa, H; Oikawa, R; Oishi, Y; Sato, Y; Suzuki, H; Suzuki, M; Toyota, M; Watanabe, Y; Yoshida, Y | 1 |
| Kim, JH; Lee, YC; Lee, YS; Shin, H | 1 |
| Bazzoli, F; Boland, CR; Daoud, Y; Fini, L; Fox, JG; Garcia, M; Gasbarrini, A; Genta, RM; Malfertheiner, P; Meyer, RL; Piazzi, G; Ricciardiello, L; Romano, M; Selgrad, M; Wex, T | 1 |
| Liu, YP; Nie, XC; Takano, Y; Xia, P; Xing, YN; Xu, XY; Yang, X; Yu, M; Zheng, HC | 1 |
| Li, CL; Li, JF; Liu, BY; Nie, H; Qu, QL; Su, LP; Wang, M; Yan, M; Yu, YY; Zhu, ZG | 1 |
| Bang, YJ; Han, SW; Im, SA; Kim, HP; Kim, TY; Lee, KH; Oh, DY; Park, J; Song, SH; Yoon, YK; Yun, J | 1 |
| Cho, BN; Cho, C; Kim, BH; Kim, YI; Lee, HK; Lee, SJ; Shim, J | 1 |
| Cao, H; Chen, XY; Fang, JY; Lu, YY; Shen, ZY; Wang, P; Wang, YC; Yu, J; Zhang, YJ; Zhu, JD | 1 |
| Deng, T; Liu, J; Luo, HS; Wang, FL; Xie, YS; Zhang, LJ; Zhang, Y | 1 |
| Choi, YH; Kang, HS; Kim, CG; Kim, GY; Kim, WJ; Shin, DY | 1 |
| Dimmler, A; El-Rifai, W; Faller, G; Frischauf, M; Hartmann, A; Jung, A; Konturek, PC; Rau, TT; Rogler, A; Schneider-Stock, R; Sehnert, B; Voll, RE | 1 |
| Chen, H; Fan, H; Peng, X; Qian, D; Qiao, F; Qiu, X; Su, X; Zhao, Z | 1 |
| Hibi, T; Hirata, K; Matsuzaki, J; Nishizawa, M; Saito, H; Saito, Y; Suzuki, H; Taya, T; Tsugawa, H | 1 |
| Bi, T; Che, X; Li, H; Liao, X; Zhang, D; Zhao, W | 1 |
| Alazzouzi, H; Andretta, E; Arango, D; Bazzocco, S; Dopeso, H; Ferreira, AM; Gebert, J; Hernandez-Losa, J; Hofstra, RM; Landolfi, S; Macaya, I; Mariadason, JM; Mateo-Lozano, S; Mazzolini, R; Mooseker, MS; Ramón y Cajal, S; Reventós, J; Rodrigues, P; Schwartz, S; Suzuki, H; Woerner, SM; Yamamoto, H | 1 |
| Chang, X; Chen, J; Dai, D; Deng, P; Li, Z; Ma, J; Zhang, S; Zhi, Y | 1 |
| Chen, Z; El-Rifai, W; Hu, TL; Peng, DF; Schneider, BG; Xu, ZK | 1 |
| Deng, N; Goh, LK; Gopalakrishnan, V; Huang, D; Ivanova, T; Lee, M; Liem, N; Luo, Q; Rozen, S; Tan, IB; Tan, P; Teh, BT; Wong, B; Wu, J; Wu, Y; Wu, YH; Yong, WP; Zhu, Y; Zouridis, H | 1 |
| Chang, X; Chen, J; Dai, D; Li, Z; Lu, Y; Ma, J; Zhang, S; Zhi, Y | 1 |
| Liu, J; Luo, HS; Wang, FL; Xie, YS; Zhang, LJ; Zhang, Y | 1 |
| Chi, SG; Lee, MG; Ryu, BK; Yoo, TH | 1 |
| Cui, L; Deng, H; Guo, J; Guo, Y; Liu, Z; Song, H; Sun, W; Xia, T; Xiao, B; Yu, X | 1 |
| Kaminishi, M; Kaneda, A; Nakanishi, Y; Sugimura, T; Ushijima, T | 1 |
| Chen, LF; Guo, WH; Ito, K; Ito, Y; Nakanishi, H; Tatematsu, M; Weng, LQ | 1 |
| Bai, AH; Chan, FK; Chan, KK; Chan, MW; Chung, SC; Leung, WK; Ng, EK; Sung, JJ; To, KF; Yu, J | 1 |
| Bang, YJ; Dimtchev, A; Jeong, SJ; Jong, HS; Jung, M; Kim, NK; Kim, TY; Lee, JW; Song, SH | 1 |
| Bang, YJ; Cho, B; Hwang, KS; Jeong, S; Jeoung, DI; Kang, GH; Kim, HY; Lee, H; Lee, HJ; Lee, YS | 1 |
| Imai, S; Kiss, C; Klein, G; Nishikawa, J; Okita, K; Szekely, L; Takada, K | 1 |
| Chan, AS; Chan, TL; Chen, X; Chu, KM; Leung, SY; Li, R; So, S; Tsui, WY; Yuen, ST | 1 |
| Chayama, K; Ito, R; Kitadai, Y; Nakayama, H; Oshimo, Y; Yasui, W; Yoshida, K | 1 |
| Correa, P; Ito, Y; Macdonald, J; Peeters, KC; Sasako, M; van de Velde, CJ; Wong, JE | 1 |
| Akino, K; Imai, K; Issa, JP; Itoh, F; Kikuchi, T; Mita, H; Murai, M; Obata, T; Ogi, K; Sasaki, Y; Satoh, A; Suzuki, H; Tokino, T; Toyota, M | 1 |
| Chen, YX; Cheng, ZH; Fang, JY; Lu, J; Lu, R; Xiao, SD; Yang, L; Zhu, HY | 1 |
| Endoh, M; Honda, T; Motoyama, T; Nishizuka, S; Tamura, G; Yanagawa, N | 1 |
| Ito, R; Nakayama, H; Oda, N; Yasui, W; Yoshida, K | 1 |
| Chen, JX; Cui, XY; Fu, PF; Wang, T | 1 |
| Chen, J; Ebert, MP; Götze, T; Klein-Hitpass, L; Leodolter, A; Malfertheiner, P; Röcken, C | 1 |
| Akino, K; Endo, T; Hinoda, Y; Imai, K; Kusano, M; Mita, H; Murai, M; Sasaki, Y; Satoh, A; Suzuki, H; Takahashi, F; Tokino, T; Toyota, M; Ueno, M; Yanagihara, K | 1 |
| Aoyagi, K; Danjoh, I; Fukaya, M; Nishigaki, M; Sakamoto, H; Sasaki, H; Yanagihara, K; Yoshida, T | 1 |
| Bae, SI; Jee, CD; Kim, WH; Lee, HS; Lee, YM; Rho, MS; Yang, HK | 1 |
| Aung, PP; Kawahara, K; Kuraoka, K; Nakayama, H; Noguchi, T; Oue, N; Shutoh, M; Yasui, W | 1 |
| Moriguchi, K; Tatematsu, M; Tsujino, Y; Ushijima, T; Yamashita, S | 2 |
| Almeida, R; David, L; LePendu, J; Mendes, N; Mesquita, P; Oliveira, C; Reis, CA; Santos-Silva, F; Serpa, J | 1 |
| Inoue, H; Kim, MS; Mori, M; Osada, M; Park, HL; Sidransky, D; Tokumaru, Y; Yamashita, K | 1 |
| Chang, MS; Jung, EJ; Kim, WH; Lee, BL; Lee, YM | 1 |
| Arai, M; Fukai, K; Imazeki, F; Kanda, T; Kurihara, T; Mikata, R; Saisho, H; Tada, M; Yokosuka, O; Zhang, K | 1 |
| Hirakawa, K; Ohira, M; Ren, J; Yashiro, M; Zhang, X | 1 |
| Choi, JS; Kim, IJ; Kim, KH; Ku, JL; Park, JG | 1 |
| Chim, CS; He, H; Jiang, SH; Kung, HF; Leung, SY; Lin, MC; Sun, YW; Tu, SP; Wang, J; Wong, BC; Yang, Y; Yu, LF; Yuen, ST; Zeng, H; Zou, B | 1 |
| Chen, GY; Ding, YB; Xia, JG | 1 |
| Huang, W; Li, B; Tian, XL; Wu, LY; Yu, LF; Zhang, YF; Zhong, J | 1 |
| Bang, YJ; Im, SA; Jong, HS; Jung, Y; Kim, TY; Park, J; Park, JH; Robertson, KD | 1 |
| Chan, FK; Cheng, YY; Jin, VX; Leung, WK; Li, J; Man, EP; Sung, JJ; Tao, Q; To, KF; Wong, YP; Yu, J | 1 |
| Cho, JS; Jang, HR; Jeong, HY; Kim, JH; Kim, M; Kim, SY; Kim, YS; Lee, KT; Noh, SM; Song, KS; Yoo, HS | 1 |
| Chen, T; Feng, XZ; He, XS; Jiang, JH; Liu, JL; Luo, Q; Tang, XF; Yang, S; Zhuang, YZ | 1 |
| Bang, YJ; Choe, KJ; Jung, CW; Kang, SH; Kim, BK; Kim, NK; Koeffler, HP; Lee, KU; Lee, YY; Seo, JY | 1 |
| Akiyoshi, T; Baba, K; Fujie, T; Li, J; Mori, M; Ueo, H; Yang, Y | 1 |
| Kim, HS; Lee, JY; Park, J; Park, JB; Shin, JY | 1 |
| Byun, DS; Chi, SG; Kang, MJ; Kim, HJ; Park, BJ; Park, JH; Park, JI | 1 |
| Bang, YJ; Choi, HH; Jong, HS; Kang, SH; Kim, NK; Kim, WH; Ryu, MH; Song, SH | 1 |
| Imai, K; Itoh, F; Kakiuchi, H; Kikuchi, T; Suzuki, H; Toyota, M | 1 |
| Bang, YJ; Choi, HH; Inoue, H; Jong, HS; Kim, NK; Song, SH; Tanabe, T | 1 |
| Ito, R; Kuniyasu, H; Kuraoka, K; Oue, N; Shigeishi, H; Yasui, W; Yokozaki, H | 1 |
| Goodison, S; Hayashi, K; Lotan, R; Oue, N; Suzuki, T; Tahara, E; Yasui, W; Yokozaki, H | 1 |
| Fujita, M; Hosokawa, M; Imai, K; Itoh, F; Kikuchi, T; Suzuki, H; Toyota, M; Yamamoto, H | 1 |
| Bae, SI; Kim, SH; Kim, WH; Lee, HS | 1 |
1 review(s) available for azacitidine and Stomach Neoplasms
| Article | Year |
|---|---|
The Role of Epigenetic Regulation in Epstein-Barr Virus-Associated Gastric Cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Core Binding Factor Alpha 3 Subunit; CpG Islands; Decitabine; DNA Methylation; DNA, Viral; Epigenesis, Genetic; Epstein-Barr Virus Infections; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Humans; MicroRNAs; RNA, Viral; Stomach Neoplasms; Tumor Protein p73 | 2017 |
146 other study(ies) available for azacitidine and Stomach Neoplasms
| Article | Year |
|---|---|
DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cells.
Topics: Azacitidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Stomach Neoplasms | 2023 |
SAMD14 promoter methylation is strongly associated with gene expression and poor prognosis in gastric cancer.
Topics: Adult; Aged; Azacitidine; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Lymphatic Metastasis; Male; Middle Aged; Prognosis; Promoter Regions, Genetic; Proportional Hazards Models; Repressor Proteins; Stomach Neoplasms | 2020 |
The impact of DNA demethylation on the upregulation of the NRN1 and TNFAIP3 genes associated with advanced gastric cancer.
Topics: Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Computational Biology; CpG Islands; Decitabine; DNA Demethylation; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Neoplasm Staging; Neuropeptides; Prognosis; Stomach Neoplasms; Transcriptome; Tumor Necrosis Factor alpha-Induced Protein 3 | 2020 |
Contribution of DNA methylation and EZH2 in SRBC down-regulation in gastric cancer.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; DNA Methylation; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Intracellular Signaling Peptides and Proteins; Male; Promoter Regions, Genetic; Pyridones; Stomach Neoplasms | 2020 |
Tumor cell-expressed IL-15Rα drives antagonistic effects on the progression and immune control of gastric cancer and is epigenetically regulated in EBV-positive gastric cancer.
Topics: Azacitidine; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Herpesvirus 4, Human; Humans; Models, Biological; Neoplasm Invasiveness; Promoter Regions, Genetic; Receptors, Interleukin-15; Recombinant Proteins; RNA, Messenger; Stomach Neoplasms; Survival Analysis; Up-Regulation | 2020 |
[Successful Endoscopic Submucosal Dissection of Early Gastric Cancer in a Patient after Azacitidine Therapy for the Treatment of Myelodysplastic Syndrome].
Topics: Aged; Azacitidine; Endoscopic Mucosal Resection; Gastric Mucosa; Humans; Male; Myelodysplastic Syndromes; Retrospective Studies; Stomach Neoplasms | 2021 |
The effect of EBV on WIF1, NLK, and APC gene methylation and expression in gastric carcinoma and nasopharyngeal cancer.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Genes, APC; Herpesvirus 4, Human; Humans; Intracellular Signaling Peptides and Proteins; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Repressor Proteins; Stomach Neoplasms | 2017 |
Inhibition of HHIP Promoter Methylation Suppresses Human Gastric Cancer Cell Proliferation and Migration.
Topics: Azacitidine; Carrier Proteins; Cell Movement; Cell Proliferation; CpG Islands; DNA Methylation; Genetic Vectors; Humans; Membrane Glycoproteins; Promoter Regions, Genetic; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Up-Regulation | 2018 |
miR-19a/b and MeCP2 repress reciprocally to regulate multidrug resistance in gastric cancer cells.
Topics: Azacitidine; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methyl-CpG-Binding Protein 2; MicroRNAs; Middle Aged; Stomach Neoplasms; Up-Regulation | 2018 |
Methylation-induced silencing of SPG20 facilitates gastric cancer cell proliferation by activating the EGFR/MAPK pathway.
Topics: Animals; Azacitidine; Base Sequence; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Female; Gene Silencing; Humans; Male; MAP Kinase Signaling System; Methylation; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multivariate Analysis; Nomograms; Prognosis; Proteins; Stomach Neoplasms; Survival Analysis; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2018 |
KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Middle Aged; Promoter Regions, Genetic; Signal Transduction; Stomach; Stomach Neoplasms; Transcription Factors; Tumor Suppressor Proteins; Up-Regulation | 2018 |
Differential expression of tescalcin by modification of promoter methylation controls cell survival in gastric cancer cells.
Topics: Azacitidine; Calcium-Binding Proteins; Cell Line, Tumor; Cell Survival; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Code; Histone Deacetylase 2; Humans; Microarray Analysis; Octamer Transcription Factor-1; Promoter Regions, Genetic; Stomach Neoplasms; Transcription Factors | 2019 |
Down-regulation of dual-specificity phosphatase 5 in gastric cancer by promoter CpG island hypermethylation and its potential role in carcinogenesis.
Topics: Azacitidine; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Down-Regulation; Dual-Specificity Phosphatases; Epigenesis, Genetic; Extracellular Signal-Regulated MAP Kinases; Female; G1 Phase Cell Cycle Checkpoints; Gastric Mucosa; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Humans; Male; Middle Aged; Multivariate Analysis; Phosphorylation; Prognosis; Promoter Regions, Genetic; Reproducibility of Results; Stomach Neoplasms | 2013 |
Altered expression of PTCH and HHIP in gastric cancer through their gene promoter methylation: novel targets for gastric cancer.
Topics: Adult; Aged; Apoptosis; Azacitidine; Carrier Proteins; Cell Survival; CpG Islands; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Membrane Glycoproteins; Middle Aged; Molecular Targeted Therapy; Patched Receptors; Patched-1 Receptor; Promoter Regions, Genetic; Receptors, Cell Surface; RNA, Messenger; Stomach Neoplasms | 2013 |
Gastric cancer prevention by demethylation.
Topics: Adenocarcinoma; Animals; Azacitidine; Decitabine; DNA-Cytosine Methylases; Helicobacter Infections; Helicobacter pylori; Male; Stomach Neoplasms | 2013 |
Prevention of Helicobacter pylori-induced gastric cancers in gerbils by a DNA demethylating agent.
Topics: Adenocarcinoma; Animals; Azacitidine; Carcinogens; Decitabine; Disease Models, Animal; DNA Methylation; DNA-Cytosine Methylases; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Methylnitrosourea; Stomach Neoplasms | 2013 |
Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; Enzyme Inhibitors; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HCT116 Cells; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; RNA, Small Interfering; Stomach Neoplasms; Tumor Suppressor Protein p53; Up-Regulation | 2013 |
Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer.
Topics: Azacitidine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Methyl-CpG-Binding Protein 2; MicroRNAs; Nerve Tissue Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Stomach Neoplasms; Transfection | 2013 |
Identification of genes specifically methylated in Epstein-Barr virus-associated gastric carcinomas.
Topics: Aged; Azacitidine; Carcinoma; Cell Line, Tumor; Cytoskeletal Proteins; Decitabine; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Epstein-Barr Virus Infections; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Homeodomain Proteins; Humans; Hydroxamic Acids; Male; Microfilament Proteins; Middle Aged; Neoplasm Proteins; Nerve Tissue Proteins; Nuclear Proteins; Oncogene Proteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Transcription Factors; Tumor Protein p73; Tumor Suppressor Proteins | 2013 |
The Tumor Suppressor Roles of miR-433 and miR-127 in Gastric Cancer.
Topics: 3' Untranslated Regions; Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Hydroxamic Acids; Male; MicroRNAs; Middle Aged; Neoplasm Staging; ras Proteins; Stomach Neoplasms | 2013 |
Expression of 17β-hydroxysteroid dehydrogenase type 1 in gastric cancer.
Topics: Aged; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Estradiol; Estradiol Dehydrogenases; Estrone; Female; Humans; Male; Methylation; Stomach Neoplasms; Up-Regulation | 2013 |
Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer.
Topics: Aged; Animals; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Cell Movement; CpG Islands; Decitabine; DNA Methylation; Epigenomics; Female; Galectins; Genes, Tumor Suppressor; Heterografts; Humans; Male; Mice; Mice, Nude; Middle Aged; Promoter Regions, Genetic; RNA, Messenger; Stomach Neoplasms | 2013 |
DNA methylation of trefoil factor 1 (TFF1) is associated with the tumorigenesis of gastric carcinoma.
Topics: Apoptosis; Azacitidine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Gene Expression Regulation; Humans; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Trefoil Factor-1; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2014 |
Detection of aberrant hypermethylated spastic paraplegia-20 as a potential biomarker and prognostic factor in gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Case-Control Studies; Cell Cycle Proteins; DNA Methylation; Female; Follow-Up Studies; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Polymerase Chain Reaction; Prognosis; Promoter Regions, Genetic; Proteins; Stomach; Stomach Neoplasms; Survival Rate; Tumor Cells, Cultured | 2014 |
Down-regulation of thyroid hormone receptor β1 gene expression in gastric cancer involves promoter methylation.
Topics: Azacitidine; Cell Line; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Thyroid Hormone Receptors beta | 2014 |
DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer.
Topics: Aged; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Guanine Nucleotide Exchange Factors; Humans; Hydroxamic Acids; Male; MicroRNAs; Middle Aged; Real-Time Polymerase Chain Reaction; Stomach Neoplasms; T-Lymphoma Invasion and Metastasis-inducing Protein 1 | 2015 |
Genetic regulation of MUC1 expression by Helicobacter pylori in gastric cancer cells.
Topics: Azacitidine; Binding Sites; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Helicobacter pylori; Host-Pathogen Interactions; Humans; Immunoblotting; Mucin-1; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; Stomach Neoplasms; Up-Regulation | 2014 |
Epigenetic silencing of miRNA-9 is correlated with promoter-proximal CpG island hypermethylation in gastric cancer in vitro and in vivo.
Topics: Adult; Aged; Animals; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; MicroRNAs; Middle Aged; Promoter Regions, Genetic; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; DNA Methylation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Silencing; Genes, Reporter; Humans; Mice; Mice, Inbred BALB C; MicroRNAs; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Oligonucleotide Array Sequence Analysis; Stomach Neoplasms; Transfection | 2014 |
Methylation-associated silencing of miR-495 inhibit the migration and invasion of human gastric cancer cells by directly targeting PRL-3.
Topics: Azacitidine; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Gene Silencing; Genes, Tumor Suppressor; Humans; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Sequence Analysis, DNA; Stomach Neoplasms | 2015 |
CpG island promoter hypermethylation of Ras association domain family 1A gene contributes to gastric carcinogenesis.
Topics: Azacitidine; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; CpG Islands; Decitabine; DNA Methylation; Gene Expression; Gene Silencing; Humans; Neoplasm Staging; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Suppressor Proteins | 2015 |
Hypermethylation of the interferon regulatory factor 5 promoter in Epstein-Barr virus-associated gastric carcinoma.
Topics: Azacitidine; Burkitt Lymphoma; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Herpesvirus 4, Human; Humans; Interferon Regulatory Factors; Promoter Regions, Genetic; Sequence Analysis, DNA; Stomach Neoplasms; Virus Latency | 2015 |
Gelatinases-stimuli nanoparticles encapsulating 5-fluorouridine and 5-aza-2'-deoxycytidine enhance the sensitivity of gastric cancer cells to chemical therapeutics.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Stability; Enzyme Activation; Epigenesis, Genetic; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nanoparticles; Stomach Neoplasms; Time Factors; Transcription Factor AP-2 | 2015 |
DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression.
Topics: Adenosine; Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Decitabine; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Histones; Humans; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Polycomb Repressive Complex 2; Stomach Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Downregulation of A disintegrin and metallopeptidase with thrombospondin motif type 1 by DNA hypermethylation in human gastric cancer.
Topics: ADAM Proteins; ADAMTS1 Protein; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Case-Control Studies; Cell Line, Tumor; Cell Movement; Collagen; Decitabine; DNA Methylation; Drug Combinations; Epigenesis, Genetic; Female; Humans; Laminin; Lymphatic Metastasis; Male; Middle Aged; Molecular Sequence Data; Proteoglycans; RNA, Messenger; Stomach Neoplasms; Tumor Burden | 2015 |
DNA methylation inhibitor, decitabine, promotes MGC803 gastric cancer cell migration and invasion via the upregulation of NEDD4‑1.
Topics: Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Endosomal Sorting Complexes Required for Transport; Humans; Nedd4 Ubiquitin Protein Ligases; Neoplasm Invasiveness; Stomach Neoplasms; Ubiquitin-Protein Ligases; Up-Regulation | 2015 |
The transcribed-ultraconserved regions in prostate and gastric cancer: DNA hypermethylation and microRNA-associated regulation.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Cell Proliferation; Conserved Sequence; DNA Methylation; DNA, Neoplasm; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Middle Aged; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms | 2016 |
Methylation and expression of Epstein-Barr virus latent membrane protein 1, 2A and 2B in EBV-associated gastric carcinomas and cell lines.
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Epstein-Barr Virus Infections; Gene Expression Regulation, Neoplastic; Gene Silencing; Herpesvirus 4, Human; Humans; Promoter Regions, Genetic; Stomach Neoplasms; Viral Matrix Proteins; Virus Latency | 2016 |
Decitabine inhibits tumor cell proliferation and up-regulates e-cadherin expression in Epstein-Barr virus-associated gastric cancer.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cadherins; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; Epithelial Cells; Epstein-Barr Virus Infections; Humans; Stomach Neoplasms | 2017 |
Downregulation of ADAMTS8 by DNA Hypermethylation in Gastric Cancer and Its Clinical Significance.
Topics: ADAMTS Proteins; Aged; Azacitidine; Cell Line, Tumor; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; RNA, Messenger; Stomach Neoplasms | 2016 |
[Methylation and demethylation of SOX2 gene promoter in BGC-823 gastric cancer cells].
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; RNA, Messenger; SOXB1 Transcription Factors; Stomach Neoplasms; Tumor Burden | 2016 |
Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Base Sequence; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Decitabine; Down-Regulation; Humans; Methylation; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stomach Neoplasms; TOR Serine-Threonine Kinases; Transcription, Genetic; Up-Regulation | 2008 |
[Methylation of PTPRG gene and its regulation in gastric cancer].
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Humans; Lymph Nodes; Lymphatic Metastasis; Receptor-Like Protein Tyrosine Phosphatases, Class 5; RNA, Messenger; Stomach Neoplasms | 2008 |
Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Histones; Humans; Hydroxamic Acids; RNA, Messenger; Sequence Analysis, DNA; Stomach Neoplasms | 2008 |
LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer.
Topics: Acetylation; Animals; Azacitidine; Base Sequence; Blotting, Southern; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Primers; Down-Regulation; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms | 2008 |
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells.
Topics: Acetylation; Azacitidine; Cell Hypoxia; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histocompatibility Antigens; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Humans; Hydroxamic Acids; Methylation; Neoplasm Proteins; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Stomach Neoplasms; Transcription, Genetic | 2009 |
DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells.
Topics: Apoptosis; Azacitidine; Cell Division; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Modification Methylases; Enzyme Inhibitors; G2 Phase; Humans; Radiation-Sensitizing Agents; Stomach Neoplasms | 2009 |
[Histone H3 lysine 9 methylation is associated with the expression of hMLH1 and DNA methylation in gastric cancer cells].
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Cell Line, Tumor; DNA Methylation; DNA Mismatch Repair; Gene Expression; Genes, Tumor Suppressor; Histones; Humans; MutL Protein Homolog 1; Nuclear Proteins; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms | 2008 |
[5-Aza-CdR regulates the expression of RASSF1A gene in human gastric cancer cell line and inhibits the growth of cells].
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Stomach Neoplasms; Tumor Suppressor Proteins | 2009 |
GSTP1 determines cis-platinum cytotoxicity in gastric adenocarcinoma MGC803 cells: regulation by promoter methylation and extracellular regulated kinase signaling.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Azacitidine; Cell Line, Tumor; Cisplatin; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Humans; Inactivation, Metabolic; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Transcription, Genetic | 2009 |
Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.
Topics: Alu Elements; Apoptosis; Azacitidine; Cell Line, Tumor; Chromatin Assembly and Disassembly; Chromosomes, Human, Pair 19; Decitabine; DNA Methylation; DNA Polymerase II; DNA Polymerase III; Down-Regulation; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Humans; MicroRNAs; Myeloid Cell Leukemia Sequence 1 Protein; Phenylbutyrates; Proto-Oncogene Proteins c-bcl-2; Stomach Neoplasms | 2009 |
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer.
Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; CpG Islands; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Decitabine; Dinoprostone; DNA Methylation; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxyprostaglandin Dehydrogenases; Immunohistochemistry; Interleukin-1beta; Nitrobenzenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; Sulfonamides; Transfection | 2009 |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells].
Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Genes, p16; Humans; Hydroxamic Acids; MutL Protein Homolog 1; Nuclear Proteins; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Suppressor Proteins | 2009 |
Development of a novel output value for quantitative assessment in methylated DNA immunoprecipitation-CpG island microarray analysis.
Topics: Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Humans; Immunoprecipitation; Oligonucleotide Array Sequence Analysis; Stomach Neoplasms | 2009 |
Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells.
Topics: Acetylation; Azacitidine; Blotting, Western; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Enzyme Inhibitors; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunoprecipitation; Lysine; Polymerase Chain Reaction; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Cells, Cultured | 2009 |
Expression and mutation analysis of TIG1 (tazarotene-induced gene 1) in human gastric cancer.
Topics: Azacitidine; Cell Line, Tumor; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; Humans; Membrane Proteins; Mutation; RNA, Messenger; Stomach Neoplasms | 2009 |
Role of histone modifications and DNA methylation in the regulation of O6-methylguanine-DNA methyltransferase gene expression in human stomach cancer cells.
Topics: Acetylation; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Gene Expression Regulation, Neoplastic; Histones; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Suppressor Proteins | 2010 |
Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells.
Topics: Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Claudins; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Neoplasm Invasiveness; Nerve Tissue Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stomach Neoplasms | 2009 |
Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis.
Topics: 3' Untranslated Regions; Azacitidine; Cell Line, Tumor; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; Gene Silencing; Humans; MicroRNAs; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Receptor, Notch4; Receptors, Notch; Stomach Neoplasms | 2010 |
Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation.
Topics: Acetylation; Apoptosis; Azacitidine; Butyrates; Cell Line, Tumor; Decitabine; Early Growth Response Protein 1; Gene Knockdown Techniques; Histones; Humans; Hydroxamic Acids; p300-CBP Transcription Factors; Promoter Regions, Genetic; PTEN Phosphohydrolase; Stomach Neoplasms; Up-Regulation; Vitamin D | 2010 |
Aberrant methylation impairs low density lipoprotein receptor-related protein 1B tumor suppressor function in gastric cancer.
Topics: Animals; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Chi-Square Distribution; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; ROC Curve; Statistics, Nonparametric; Stomach Neoplasms; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2010 |
Tissue factor pathway inhibitor 2 (TFPI2) is frequently silenced by aberrant promoter hypermethylation in gastric cancer.
Topics: Adult; Aged; Azacitidine; Cell Line, Tumor; CpG Islands; DNA Methylation; Female; Gene Silencing; Glycoproteins; Humans; Male; Middle Aged; Promoter Regions, Genetic; RNA, Messenger; Stomach Neoplasms | 2010 |
Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.
Topics: Adult; Aged; Apoptosis; Azacitidine; Blotting, Western; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Core Binding Factor Alpha 3 Subunit; CpG Islands; Cyclin-Dependent Kinase Inhibitor p27; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Neoplasm Staging; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Time Factors; Up-Regulation; Young Adult | 2010 |
DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae.
Topics: Aged; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA, Neoplasm; Down-Regulation; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Interferon Regulatory Factor-1; Interferon Regulatory Factors; Male; Middle Aged; Stomach Neoplasms | 2010 |
S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Cell Cycle Proteins; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Female; Humans; Hydroxamic Acids; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Prognosis; Promoter Regions, Genetic; Protein Synthesis Inhibitors; S100 Calcium Binding Protein A6; S100 Proteins; Stomach Neoplasms; Up-Regulation | 2010 |
Promoter hypermethylation and histone hypoacetylation contribute to pancreatic-duodenal homeobox 1 silencing in gastric cancer.
Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Homeodomain Proteins; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Trans-Activators; Tumor Cells, Cultured | 2010 |
Epigenetic regulation of miR-196b expression in gastric cancer.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Primers; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; MicroRNAs; Polymerase Chain Reaction; Promoter Regions, Genetic; Stomach Neoplasms; Transcription, Genetic | 2010 |
Epigenetic silencing of somatostatin in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Methylation; Predictive Value of Tests; Reproducibility of Results; RNA, Messenger; Somatostatin; Stomach Neoplasms | 2011 |
Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c.
Topics: 3' Untranslated Regions; Azacitidine; Base Sequence; Carrier Proteins; Cell Line; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; HEK293 Cells; Humans; Luciferases; Membrane Proteins; MicroRNAs; Promoter Regions, Genetic; Stomach Neoplasms | 2011 |
Silence of HIN-1 expression through methylation of its gene promoter in gastric cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cytokines; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Middle Aged; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Suppressor Proteins | 2011 |
Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Azacitidine; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Promoter Regions, Genetic; Stomach Neoplasms | 2011 |
DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Carcinoma; Cisplatin; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Molecular Targeted Therapy; Multivariate Analysis; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Stomach Neoplasms; Treatment Outcome; Tumor Stem Cell Assay | 2011 |
Clinical significance of expression of Hint1 and potential epigenetic mechanism in gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Decitabine; Epigenesis, Genetic; Epstein-Barr Virus Infections; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Helicobacter Infections; Hep G2 Cells; Humans; Male; Middle Aged; Neoplasm Staging; Nerve Tissue Proteins; Stomach Neoplasms | 2011 |
Decreased expression of protease-activated receptor 4 in human gastric cancer.
Topics: Aged; Azacitidine; Cell Line, Tumor; Decitabine; DNA Modification Methylases; Down-Regulation; Female; Gastric Mucosa; Gene Expression; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Humans; Male; Methylation; Middle Aged; Promoter Regions, Genetic; Receptors, Thrombin; Sequence Analysis, DNA; Stomach Neoplasms | 2011 |
Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Down-Regulation; Epigenomics; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; MicroRNAs; Polymerase Chain Reaction; RNA, Neoplasm; Stomach Neoplasms | 2011 |
Down-regulation of CXCL12 by DNA hypermethylation and its involvement in gastric cancer metastatic progression.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Transformed; Cell Line, Tumor; Chemokine CXCL12; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Grading; Receptors, CXCR; Receptors, CXCR4; Stomach Neoplasms | 2012 |
Hypermethylation of Sox17 gene is useful as a molecular diagnostic application in early gastric cancer.
Topics: Aged; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; CpG Islands; Decitabine; Disease Progression; DNA Methylation; Early Detection of Cancer; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Risk; SOXF Transcription Factors; Stomach Neoplasms | 2012 |
Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; Azacitidine; beta Catenin; Butyrates; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histone Deacetylase Inhibitors; Histones; Humans; Intercellular Signaling Peptides and Proteins; Male; Membrane Proteins; Middle Aged; Promoter Regions, Genetic; Stomach Neoplasms; Transfection; Wnt Signaling Pathway | 2012 |
Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer.
Topics: Animals; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Calcium-Binding Proteins; Cell Differentiation; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Helicobacter Infections; Helicobacter pylori; Homeodomain Proteins; Humans; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Membrane Proteins; Mice; Promoter Regions, Genetic; Receptor, Notch1; Serrate-Jagged Proteins; Signal Transduction; Stomach Neoplasms; Transcription Factor HES-1 | 2011 |
The roles of REIC gene and its encoding product in gastric carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Azacitidine; beta Catenin; Biomarkers, Tumor; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokines; Cyclin D2; Cyclin E; Decitabine; Gastric Mucosa; Humans; Intercellular Signaling Peptides and Proteins; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Pseudopodia; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; TOR Serine-Threonine Kinases; Wiskott-Aldrich Syndrome Protein Family | 2012 |
microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis.
Topics: 3' Untranslated Regions; Azacitidine; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HEK293 Cells; Humans; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Smad2 Protein; Stomach Neoplasms | 2012 |
Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azacitidine; Cell Line, Tumor; Cetuximab; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epidermal Growth Factor; Epigenesis, Genetic; Epiregulin; ErbB Receptors; Gene Knockdown Techniques; Gene Silencing; Histones; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2012 |
Transcriptional silencing of the inhibin-α gene in human gastric carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Inhibins; Loss of Heterozygosity; Promoter Regions, Genetic; Sequence Analysis, DNA; Stomach Neoplasms; Transcription, Genetic | 2012 |
CTHRC1 is upregulated by promoter demethylation and transforming growth factor-β1 and may be associated with metastasis in human gastric cancer.
Topics: Apoptosis; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Survival; Decitabine; DNA Methylation; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Metaplasia; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Stomach Neoplasms; Transforming Growth Factor beta1; Up-Regulation | 2012 |
5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.
Topics: Apoptosis; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Core Binding Factor Alpha 3 Subunit; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; DNA Methyltransferase 3A; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Lung Neoplasms; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2012 |
Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Movement; Claudins; Decitabine; DNA Modification Methylases; Gene Expression; Humans; Lipopolysaccharides; Matrix Metalloproteinases, Secreted; Proto-Oncogene Proteins c-akt; Stomach Neoplasms; Tight Junctions | 2012 |
Methylation-dependent activation of CDX1 through NF-κB: a link from inflammation to intestinal metaplasia in the human stomach.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Base Sequence; Chromatin; Conserved Sequence; CpG Islands; DNA Methylation; Female; Gastric Mucosa; Gastritis; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Inflammation; Intestinal Mucosa; Intestines; Male; Metaplasia; Middle Aged; Molecular Sequence Data; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Stomach; Stomach Neoplasms; Tumor Necrosis Factor-alpha; Young Adult | 2012 |
Enforced expression of RASAL1 suppresses cell proliferation and the transformation ability of gastric cancer cells.
Topics: Aged; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Epigenesis, Genetic; Epstein-Barr Virus Infections; Female; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Helicobacter Infections; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Middle Aged; ras GTPase-Activating Proteins; Stomach Neoplasms | 2012 |
Development of a novel microRNA promoter microarray for ChIP-on-chip assay to identify epigenetically regulated microRNAs.
Topics: Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA Modification Methylases; Down-Regulation; Epigenesis, Genetic; Histones; Humans; MicroRNAs; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Stomach Neoplasms | 2012 |
Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer.
Topics: Apoptosis; Azacitidine; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Lymphatic Metastasis; Male; Middle Aged; Promoter Regions, Genetic; Protocadherins; RNA, Messenger; Stomach Neoplasms; Up-Regulation | 2012 |
Brush border myosin Ia inactivation in gastric but not endometrial tumors.
Topics: Azacitidine; Base Sequence; Blotting, Western; Decitabine; DNA Methylation; DNA Primers; Endometrial Neoplasms; Female; Humans; Microscopy, Confocal; Microvilli; Mutation; Myosin Heavy Chains; Myosin Type I; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms | 2013 |
DNA methylation of NDRG2 in gastric cancer and its clinical significance.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Cell Line, Tumor; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Middle Aged; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Stomach Neoplasms; Transfection; Tumor Suppressor Proteins | 2013 |
Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas.
Topics: Azacitidine; Case-Control Studies; Cell Line, Tumor; Decitabine; DNA Methylation; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Gene Silencing; Glutathione Peroxidase; Humans; Lymphatic Metastasis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms | 2012 |
Methylation subtypes and large-scale epigenetic alterations in gastric cancer.
Topics: Animals; Azacitidine; Cell Proliferation; Chromosomal Instability; Cluster Analysis; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Epigenomics; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mice; Neoplasm Transplantation; Phenotype; Stomach Neoplasms | 2012 |
Association of NDRG1 gene promoter methylation with reduced NDRG1 expression in gastric cancer cells and tissue specimens.
Topics: Azacitidine; Base Sequence; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Exons; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Histones; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; RNA, Messenger; Stomach Neoplasms | 2013 |
Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A).
Topics: Androstadienes; Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Azacitidine; Cell Cycle Proteins; Cell Line, Tumor; Comet Assay; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Damage; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; G2 Phase Cell Cycle Checkpoints; Humans; Protein Serine-Threonine Kinases; Signal Transduction; Stomach Neoplasms; Time Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin | 2013 |
CD81 is a candidate tumor suppressor gene in human gastric cancer.
Topics: Apoptosis; Azacitidine; Base Sequence; Blotting, Western; Cell Cycle; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Stomach Neoplasms; Tetraspanin 28; Tumor Suppressor Proteins | 2013 |
MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigenetical regulation in gastric cancer.
Topics: Azacitidine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; CpG Islands; Cyclin-Dependent Kinase 6; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; MicroRNAs; Promoter Regions, Genetic; Signal Transduction; Stomach Neoplasms; Vascular Endothelial Growth Factor A | 2013 |
Reduced expression of the insulin-induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers.
Topics: Actin-Related Protein 2-3 Complex; Actins; Adult; Aged; Aged, 80 and over; Azacitidine; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Middle Aged; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tumor Cells, Cultured | 2002 |
Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor.
Topics: Animals; Azacitidine; Base Sequence; Cell Division; Core Binding Factor Alpha 3 Subunit; CpG Islands; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Gene Silencing; Genes, Tumor Suppressor; Hydroxamic Acids; Mice; Molecular Sequence Data; Promoter Regions, Genetic; RNA, Messenger; Stomach Neoplasms; Transcription Factors | 2002 |
Inactivation of helicase-like transcription factor by promoter hypermethylation in human gastric cancer.
Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Azacitidine; Carrier Proteins; CpG Islands; DNA Methylation; DNA-Binding Proteins; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Sequence Analysis, DNA; Stomach Neoplasms; Sulfites; Transcription Factors; Tumor Cells, Cultured | 2003 |
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells.
Topics: Acetylation; Acetyltransferases; Alleles; Azacitidine; Blotting, Northern; Blotting, Southern; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; GTPase-Activating Proteins; Histone Acetyltransferases; Histones; Humans; Hydroxamic Acids; Neoplasm Proteins; Protein Processing, Post-Translational; RNA, Messenger; RNA, Neoplasm; Saccharomyces cerevisiae Proteins; Stomach Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma.
Topics: Antigens, Nuclear; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Biomarkers, Tumor; CpG Islands; DEAD-box RNA Helicases; Decitabine; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Methylation; Molecular Sequence Data; Neoplasm Staging; Nuclear Proteins; Oligonucleotide Probes; Precancerous Conditions; Promoter Regions, Genetic; Stomach Neoplasms; Transcription Factors; Tumor Cells, Cultured | 2003 |
Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV).
Topics: Azacitidine; Blotting, Northern; Blotting, Western; CpG Islands; Cysteine Proteinase Inhibitors; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Herpesvirus 4, Human; Humans; Keratins; Leupeptins; Oligonucleotide Array Sequence Analysis; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tumor Cells, Cultured; Up-Regulation | 2003 |
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
Topics: Adenocarcinoma; Azacitidine; Cell Line; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Helix-Loop-Helix Motifs; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Inhibitor of Differentiation Proteins; Microsatellite Repeats; Promoter Regions, Genetic; Stomach Neoplasms; Transcription Factors | 2003 |
Promoter methylation of cyclin D2 gene in gastric carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; CpG Islands; Cyclin D2; Cyclins; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Models, Genetic; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms | 2003 |
Therapeutic strategies in gastric cancer.
Topics: Animals; Azacitidine; Core Binding Factor Alpha 3 Subunit; DNA-Binding Proteins; Enzyme Inhibitors; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Methyltransferases; Mice; Mice, Nude; Stomach Neoplasms; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cell Separation; Chromatin; Colorectal Neoplasms; CpG Islands; Decitabine; Depsipeptides; DNA Methylation; Doxorubicin; Flow Cytometry; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Models, Genetic; Neuropeptides; Oligopeptides; Polymerase Chain Reaction; Precipitin Tests; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Sulfites | 2003 |
5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of p16INK4A gene in human gastric cancer cell lines.
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Genes, p16; Genes, Tumor Suppressor; Humans; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Transcription, Genetic; Up-Regulation | 2004 |
Demethylation of the synuclein gamma gene CpG island in primary gastric cancers and gastric cancer cell lines.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Division; Cell Line, Tumor; CpG Islands; Decitabine; Disease Progression; DNA Methylation; DNA, Complementary; Exons; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Metastasis; Nerve Tissue Proteins; Polymorphism, Single-Stranded Conformational; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Sulfites; Synucleins; Time Factors | 2004 |
Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality.
Topics: Adenoma; Azacitidine; Decitabine; Disease Progression; DNA Methylation; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Immunoenzyme Techniques; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Promoter Regions, Genetic; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serpins; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2004 |
Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines.
Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Female; Humans; Male; Nerve Tissue Proteins; Prostatic Neoplasms; RNA, Messenger; Stomach Neoplasms | 2004 |
Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; CpG Islands; Decitabine; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Cells, Cultured | 2004 |
Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer.
Topics: Acetylation; Azacitidine; Base Sequence; Blotting, Western; Cell Line, Tumor; Colorectal Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylases; Histones; Humans; Membrane Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Sequence Analysis, DNA; Stomach Neoplasms | 2005 |
Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Cell Survival; Cluster Analysis; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Genome, Human; GTP Phosphohydrolases; Humans; Hydroxamic Acids; Introns; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; ras Proteins; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Transcriptional Activation | 2005 |
Loss of caspase-1 gene expression in human gastric carcinomas and cell lines.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Caspase 1; Decitabine; DNA Methylation; Female; Gene Expression Profiling; Histones; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Prognosis; Stomach Neoplasms; Survival Analysis; Tumor Cells, Cultured | 2005 |
DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Adenosquamous; DNA Methylation; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Intestinal Neoplasms; Male; Membrane Proteins; Metaplasia; Middle Aged; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoids; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 2005 |
Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Decitabine; Delta-5 Fatty Acid Desaturase; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genomics; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Stomach Neoplasms; Up-Regulation | 2006 |
Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation.
Topics: Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Primers; Fucosyltransferases; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Luciferases; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms | 2006 |
PGP9.5 methylation in diffuse-type gastric cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Cell Line, Tumor; Decitabine; DNA Methylation; Genes, Tumor Suppressor; Humans; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Stomach Neoplasms; Ubiquitin Thiolesterase | 2006 |
Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir.
Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Ganciclovir; Herpesvirus 4, Human; Humans; Hydroxamic Acids; Protein Processing, Post-Translational; Signal Transduction; Stomach Neoplasms; Virus Activation | 2007 |
Analysis of genes upregulated by the demethylating agent 5-aza-2'-deoxycytidine in gastric cancer cell lines.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA, Complementary; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Methylation; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Stomach Neoplasms; Sulfates; Time Factors; Up-Regulation | 2006 |
Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Modification Methylases; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Humans; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms | 2006 |
Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites.
Topics: Azacitidine; Cell Line, Tumor; CpG Islands; DNA Methylation; Epithelial Cells; Gastric Mucosa; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Stomach Neoplasms; Up-Regulation | 2007 |
Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Colorectal Neoplasms; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Melanoma-Specific Antigens; Neoplasm Proteins; Promoter Regions, Genetic; RNA, Messenger; Stomach Neoplasms | 2006 |
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Neoplasm Proteins; Promoter Regions, Genetic; Protein Synthesis Inhibitors; RNA, Messenger; Stomach Neoplasms | 2006 |
[Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer].
Topics: Animals; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Nude; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Stomach Neoplasms; Syk Kinase | 2006 |
Downregulation and CpG island hypermethylation of NES1/hK10 gene in the pathogenesis of human gastric cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Transformed; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; In Situ Hybridization; Kallikreins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms | 2007 |
Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; RNA, Small Interfering; Stomach Neoplasms; Transfection | 2007 |
Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Animals; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; DNA Methylation; DNA Primers; Epigenesis, Genetic; Eye Proteins; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Nude; Promoter Regions, Genetic; Proto-Oncogene Proteins; Stomach Neoplasms | 2007 |
Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer.
Topics: Azacitidine; Decitabine; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genetic Testing; Humans; Lymph Nodes; Lymphatic Metastasis; Receptor-Like Protein Tyrosine Phosphatases, Class 5; RNA, Messenger; Stomach Neoplasms | 2007 |
Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Cell Line, Tumor; Chromatin; CpG Islands; DNA Methylation; DNA, Neoplasm; Drug Synergism; Enzyme Inhibitors; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; MutL Protein Homolog 1; Nuclear Proteins; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Suppressor Protein p14ARF | 2007 |
Regulation of demethylation and re-expression of RASSF1A gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Butyrates; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Therapy, Combination; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Stomach Neoplasms; Tumor Suppressor Proteins | 2008 |
Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; DNA Restriction Enzymes; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome, Human; Humans; Hydroxamic Acids; Male; Membrane Proteins; Middle Aged; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Stomach Neoplasms | 2008 |
Investigation of transcriptional gene silencing and mechanism induced by shRNAs targeted to RUNX3 in vitro.
Topics: Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; Time Factors; Transcription, Genetic; Transfection | 2008 |
Alterations of p16INK4A and p15INK4B genes in gastric carcinomas.
Topics: Adenocarcinoma; Azacitidine; Carrier Proteins; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA Mutational Analysis; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1997 |
Expression of BAGE, GAGE, and MAGE genes in human gastric carcinoma.
Topics: Aged; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA, Neoplasm; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Male; Melanoma-Specific Antigens; Middle Aged; Neoplasm Proteins; Stomach; Stomach Neoplasms; Tumor Cells, Cultured | 1996 |
Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells.
Topics: Azacitidine; Butyric Acid; CDC2 Protein Kinase; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Decitabine; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Microtubule-Associated Proteins; Nuclear Proteins; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2000 |
Loss of imprinting and elevated expression of wild-type p73 in human gastric adenocarcinoma.
Topics: Adenocarcinoma; Alleles; Azacitidine; Culture Media, Serum-Free; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Decitabine; DNA-Binding Proteins; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genomic Imprinting; HL-60 Cells; Humans; Mutation; Nuclear Proteins; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; U937 Cells | 2000 |
Methylation of specific CpG sites in the promoter region could significantly down-regulate p16(INK4a) expression in gastric adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Northern; Blotting, Southern; Carrier Proteins; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Down-Regulation; Female; Humans; Immunohistochemistry; Male; Middle Aged; Models, Genetic; Mutagens; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Stomach Neoplasms; Sulfites; Tumor Cells, Cultured | 2000 |
Inactivation of the 14-3-3 sigma gene is associated with 5' CpG island hypermethylation in human cancers.
Topics: 14-3-3 Proteins; Adenocarcinoma; Alleles; Animals; Azacitidine; Biomarkers, Tumor; Cell Cycle; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Exonucleases; Exoribonucleases; Fluorescence; G2 Phase; Gene Expression; Gene Silencing; Genes, p53; Humans; Mice; Mice, SCID; Neoplasm Proteins; Neoplasm Transplantation; Nucleic Acid Conformation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Protein Biosynthesis; Proteins; Stomach Neoplasms; Sulfites; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells.
Topics: Azacitidine; Blotting, Southern; Carcinoma; Chromosome Mapping; CpG Islands; Cyclooxygenase 2; Decitabine; DNA Methylation; Enzyme Induction; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Isoenzymes; Membrane Proteins; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma.
Topics: Alleles; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Genes, p53; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Inactivation of retinoic acid receptor beta by promoter CpG hypermethylation in gastric cancer.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; CpG Islands; CREB-Binding Protein; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Nuclear Proteins; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Stomach Neoplasms; Trans-Activators; Transfection; Tumor Cells, Cultured | 2001 |
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cyclooxygenase 2; Cytosine; Decitabine; DNA; DNA Methylation; Enzyme Inhibitors; Gastric Mucosa; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Isoenzymes; Membrane Proteins; Methylation; Polymorphism, Single-Stranded Conformational; Precipitin Tests; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Sulfites; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; Down-Regulation; Enzyme Inhibitors; Humans; Microsatellite Repeats; Mutation; Neoplasm Invasiveness; Neoplasm Staging; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Stomach; Stomach Neoplasms; Sulfites; Survival Rate; Transcription, Genetic; Tumor Cells, Cultured | 2002 |