Compounds > azacitidine

azacitidine and Small Cell Lung Carcinoma

azacitidine has been researched along with Small Cell Lung Carcinoma in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Althouse, S; Gentzler, R; Jalal, SI; Kalra, M; Mamdani, H; Perkins, S; Wei, CX1
Mjoli, PB; Poolman, T; Ray, DW; Singh, N; Sommer, P; Taylor, K1
Liao, W; McNutt, MA; Zhu, WG1
Borden, EC; Cheriyath, V; Luszczek, W; Mekhail, TM1
Bazhin, AV; De Smet, C; Golovastova, MO; Philippov, PP; Schmidt, J1
Kaminskyy, VO; Surova, OV; Vaculova, A; Zhivotovsky, B1
Kay, P; Matthews, L; Ray, D; Schlossmacher, G; Singh, D; Sommer, P; White, A1
Chen, D; Cheng, L; Gao, L; Lu, ZH; Pan, SY; Shu, YQ; Xie, EF; Yang, D; Zhang, JN; Zhang, LX1

Trials

1 trial(s) available for azacitidine and Small Cell Lung Carcinoma

ArticleYear
A Brief Report of a Phase II trial Evaluating Efficacy and Safety of Hypomethylating Agent Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancer.
    Clinical lung cancer, 2023, Volume: 24, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Humans; Lung Neoplasms; Small Cell Lung Carcinoma

2023

Other Studies

7 other study(ies) available for azacitidine and Small Cell Lung Carcinoma

ArticleYear
The N-terminal transactivation domain of the glucocorticoid receptor mediates apoptosis of human small cell lung cancer cells.
    Genes, chromosomes & cancer, 2014, Volume: 53, Issue:12

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mifepristone; Promoter Regions, Genetic; Protein Structure, Tertiary; Receptors, Glucocorticoid; Small Cell Lung Carcinoma; Transcriptional Activation

2014
The comet assay: a sensitive method for detecting DNA damage in individual cells.
    Methods (San Diego, Calif.), 2009, Volume: 48, Issue:1

    Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Comet Assay; Decitabine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Ethidium; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Microscopy, Fluorescence; Mutagenicity Tests; Sensitivity and Specificity; Small Cell Lung Carcinoma

2009
Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:8

    Topics: Apoptosis; Azacitidine; Benzamides; Cell Cycle; Cell Line, Tumor; Cell Survival; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Indoles; Interferons; Lung Neoplasms; Panobinostat; Phosphorylation; Pyrimidines; Small Cell Lung Carcinoma

2010
Aberrant demethylation of the recoverin gene is involved in the aberrant expression of recoverin in cancer cells.
    Experimental dermatology, 2010, Volume: 19, Issue:11

    Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Exons; Gene Expression Regulation, Neoplastic; Humans; Lung; Melanoma; Neoplasms; Promoter Regions, Genetic; Recoverin; Skin; Small Cell Lung Carcinoma

2010
Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL.
    Carcinogenesis, 2011, Volume: 32, Issue:10

    Topics: Azacitidine; Blotting, Western; Caspase 8; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Enzyme Inhibitors; Fluorescent Antibody Technique; Histone Deacetylases; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Membrane Potential, Mitochondrial; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Small Cell Lung Carcinoma; Survivin; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Valproic Acid

2011
Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Apoptosis; Azacitidine; Base Sequence; Caspase 3; Cell Line, Tumor; CpG Islands; DNA Methylation; Enzyme Inhibitors; Glucocorticoids; HEK293 Cells; Humans; Lung Neoplasms; Molecular Sequence Data; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Receptors, Glucocorticoid; Small Cell Lung Carcinoma; Transgenes

2011
[Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Adenomatous Polyposis Coli Protein; Azacitidine; Carcinoma, Large Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Genes, APC; Humans; Lung Neoplasms; Promoter Regions, Genetic; Small Cell Lung Carcinoma; Transcription, Genetic

2007