azacitidine has been researched along with Prostatic Neoplasms in 135 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (1.48) | 18.7374 |
1990's | 6 (4.44) | 18.2507 |
2000's | 61 (45.19) | 29.6817 |
2010's | 61 (45.19) | 24.3611 |
2020's | 5 (3.70) | 2.80 |
Authors | Studies |
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Chen, H; Gao, K; He, HH; Hou, X; Huang, H; Karnes, RJ; Li, Y; Pan, Y; Shi, Q; Wang, C; Wang, D; Wang, L; Wang, Y; Wei, T; Weroha, SJ; Xie, H; Yan, Y; Ye, W; Zhang, J; Zhang, P; Zhao, SM | 1 |
Jannoo, R; Kanamarlapudi, V; Row, PE; Xia, Z | 1 |
Chen, Z; Li, X; Ma, X; Wei, L; Wu, X; Zou, L | 1 |
Gao, L; Gao, S; Liang, C; Lu, X; Meng, J; Yan, F; Zhang, M; Zhou, Y | 1 |
Beller, M; Hein, JI; Junghanß, C; Murua Escobar, H; Nolte, I; Schille, JT; Weiner, F; Wu, XF | 1 |
Guruli, G; Matchavariani, K; Mchedlishvili, K; Mitskevich, N; Tsertsvadze, T | 1 |
Guo, H; Li, X; Lian, H; Liu, T; Qiu, X; Qu, F; Yang, R; Zhao, X | 1 |
Barros-Silva, D; Carneiro, I; Carvalho, AL; Costa-Pinheiro, P; Duarte, H; Evangelista, AF; Graça, I; Henrique, R; Jerónimo, C; Marques, MM; Martins, AT; Oliveira, J; Sousa, EJ | 1 |
Darwish, HA; Diab, I; Helmy, MW; Motawi, TK; Noureldin, MH | 1 |
Ambrose, M; Berry, R; Brettingham-Moore, KH; Holloway, AF; Jeffreys, SA; Joo, JE; Phillips, JL; Skala, M; Sutton, LP; Taberlay, PC; Young, A | 1 |
Ambs, S; Calin, GA; Croce, CM; Esposito, D; Hudson, RS; Liu, CG; Prueitt, RL; Schetter, AJ; Stephens, RM; Van Roosbroeck, K; Volfovsky, N; Volinia, S; Yi, M | 1 |
Desotelle, J; Jarrard, DF; Truong, M; Wagner, J; Yang, B | 1 |
Arneth, BM; Fuessel, S; Hagelgans, A; Menschikowski, M; Nacke, B; Siegert, G; Wirth, MP | 1 |
Devaney, JM; Funda, S; Furbert-Harris, P; Ittmann, M; Kwabi-Addo, B; Long, J; Taghipour, DJ; Tbaishat, R; Wang, S | 1 |
Mahajan, N; Sabherwal, Y; Zhang, M | 1 |
Chuang, CK; Lenka, G; Ng, KF; Pang, ST; Weng, WH | 1 |
Chang, Y; Chu, M; Gao, W; Guo, Y; Li, P; Zhang, K | 1 |
Baptista, T; Costa, VL; Henrique, R; Jerónimo, C; Martins, AT; Morais, A; Oliveira, AI; Oliveira, J | 1 |
Chen, D; Huang, X; Li, Z; Liu, J; Mu, D; Qu, Y; Wu, J; Zhao, F | 1 |
Adjakly, M; Bernard-Gallon, D; Bignon, YJ; Boiteux, JP; Dagdemir, A; Guy, L; Lebert, A; Ngollo, M; Penault-Llorca, F | 1 |
Ali, A; Chen, Y; Dobi, A; Haffner, MC; Li, H; McLeod, DG; Petrovics, G; Ravindranath, L; Sesterhenn, IA; Sharad, S; Srinivasan, A; Srivastava, S; Yan, W; Yegnasubramanian, S | 1 |
Cinti, C; Gherardini, L; Grimaldi, S; Naldi, I; Pani, L; Pelosi, G; Taranta, M; Viglione, F | 1 |
Ahmed, H; Bandyopadhyaya, G | 1 |
Dehghani, M; Kianpour, S; Mokarram, P; Monabati, A; Mostafavi-Pour, Z; Torabinejad, S | 1 |
Adjakly, M; Bernard-Gallon, D; Bignon, YJ; Boiteux, JP; Dagdemir, A; Guy, L; Judes, G; Karsli-Ceppioglu, S; Lebert, A; Ngollo, M; Penault-LLorca, F | 1 |
Apprey, V; Devaney, JM; Furbert-Harris, P; Ittmann, M; Kwabi-Addo, B; Lee, NH; Olender, J; Wang, BD; Wang, S | 1 |
Han, B; Lu, N; Ma, Q; Qi, M; Tan, W; Wang, L; Zhang, L | 1 |
Bin, H; Liang, W; Nan, W; Rui, T; Shuhai, Z; Wei, Z; Zhifang, M | 1 |
Chen, Y; Hu, Y; Kang, X; Liao, H; Liu, L; Xiao, Y; Yin, Z | 1 |
Chen, X; Gan, W; Han, X; Li, D; Lin, X; Liu, Y; Meng, X; Wang, L; Xiang, Z; Zhang, P | 1 |
Goto, K; Honma, R; Ishikawa, S; Matsubara, A; Oue, N; Sakamoto, N; Sentani, K; Tanimoto, K; Teishima, J; Yasui, W | 1 |
Claros, M; Nathanson, L; Ramachandran, K; Singal, R; Speer, C | 1 |
Chang, I; Dahiya, R; Deng, G; Fukuhara, S; Hashimoto, Y; Imai-Sumida, M; Kato, T; Majid, S; Mitsui, Y; Nakajima, K; Saini, S; Shiina, H; Shiina, M; Tanaka, Y; Wong, DK; Yamamura, S | 1 |
Biordi, L; Colapietro, A; Festuccia, C; Ficorella, C; Gravina, GL; Jitariuc, A; Mancini, A; Marampon, F; Sanità, P; Scarsella, L | 1 |
Balaji, KC; Lin, HK; Liu, Y; Pochampally, R; Said, N; Sharma, S; Shiozawa, Y; Watabe, K; Wu, K; Xing, F | 1 |
Clarke, PAG; Davis, R; Kwabi-Addo, B; Mumuni, S; Wang, S | 1 |
Arnold, RD; Cummings, BS; Glenn, TC; Kolli, RT; Moore, M; Scholpa, NE | 1 |
Byers, BL; Heninger, E; Jarrard, DF; Kircher, MR; Kosoff, D; Krueger, TE; Lang, JM; McNeel, DG; Sperger, JM; Thiede, SM; Yang, B | 1 |
Binnie, A; Castelo-Branco, P; de Mello, RA; Faleiro, I; Leão, R; Maia, AT | 1 |
Amos-Landgraf, J; Bryan, JN; Esebua, M; Kumar, SR; May, TJ | 1 |
Califano, JA; Henrique, R; Jeronimo, C; Kim, MS; Lee, J; Liu, JW; Moon, CS; Nagpal, JK; Ostrow, KL; Sidransky, D; Sun, W; Trink, B; Van Criekinge, W; Zhou, S | 1 |
Holmberg, AR; Liu, Z; Marquez, M; Nilsson, S | 1 |
Bologna, M; D'Alessandro, AM; Di Rocco, C; Dolo, V; Festuccia, C; Gravina, GL; Millimaggi, D; Ricevuto, E; Vicentini, C | 1 |
Avivi, L; Dotan, A; Dotan, ZA; Ramon, J | 1 |
Chihara, Y; Chuang, JC; Egger, G; Friedman, JM; Liang, G; Saito, Y | 1 |
Bologna, M; D'Alessandro, AM; Dolo, V; Festuccia, C; Gravina, GL; Millimaggi, D; Muzi, P; Ricevuto, E; Vicentini, C | 1 |
Feng, L; Liu, Q; Liu, Y; Lv, W; Shang, D; Tian, Y; Zhang, F | 1 |
Gopisetty, G; Gordian, E; Hader, C; Navarro, L; Ramachandran, K; Reis, IM; Schulz, WA; Singal, R | 1 |
Bapat, B; Briollais, L; Fleshner, N; Kron, K; Ozcelik, H; Pethe, V; Pinthus, J; Sadikovic, B; Sunderji, A; van der Kwast, T; Venkateswaran, V | 1 |
Chiyomaru, T; Enokida, H; Kagara, I; Kawahara, K; Kawakami, K; Mori, K; Nakagawa, M; Nishiyama, K; Seki, N; Tatarano, S | 1 |
Foster, BA; Karpf, AR; Mavis, CK; Morey Kinney, SR | 1 |
Gorantla, B; Knost, JA; Pulukuri, SM; Rao, JS | 1 |
Biordi, L; Festuccia, C; Ficorella, C; Flati, V; Gravina, GL; Martella, F; Ricevuto, E; Tombolini, V | 1 |
Chen, Z; Koeffler, HP; Mishra, DK; Sarkissyan, M; Vadgama, JV; Wu, Y | 1 |
Cheung, KL; Foster, BA; Huang, Y; Kan, YW; Khor, TO; Kong, AN; Li, W; Wu, TY; Yu, S | 1 |
Cheng, W; Du, X; Huang, Q; Huang, W; Jiang, L; Lai, D; Liu, T; Liu, Z; Xu, F; Zhao, Y | 1 |
Bonfili, P; Di Staso, M; Festuccia, C; Gravina, GL; Jannini, EA; Marampon, F; Pestell, RG; Tombolini, V; Vitturini, A | 1 |
Bentov, I; Plymate, SR; Schayek, H; Sun, S; Werner, H | 1 |
Ahn, JS; He, L; Jang, KL; Jeong, SJ; Jung, M; Kim, BY; Kim, SO; Kwon, O; Lee, HG; Osada, H | 1 |
Gutkin, DW; Shurin, GV; Shurin, MR; Song, EY; Tourkova, IL | 1 |
Deeb, KK; Johnson, CS; Karpf, AR; Luo, W; Morrison, CD; Muindi, JR; Trump, DL | 1 |
Chen, Y; Dahiya, R; Deng, G; Khatri, G; Liu, J; Majid, S; Saini, S; Shahryari, V; Suh, SO; Tanaka, Y; Zaman, MS | 1 |
Du, J; Gong, J; Guan, M; Hu, J; Hu, T; Jiang, H; Liu, W; Lu, Y; Sun, C; Sun, Y | 1 |
Bhatnagar, N; Guo, B; Li, X; Padi, SK; Tang, MS; Zhang, Q | 1 |
Abel, PW; Deng, C; Gatalica, Z; Lin, MF; Tu, Y; Wang, B; Wang, J; Wolff, DW; Xie, Y; Yang, M | 1 |
Kim, EJ; Kim, IY; Kim, SK; Kim, WJ; Kim, YJ; Kim, YW; Yoon, HY | 1 |
Costa, VL; Danielsen, SA; Eknaes, M; Henrique, R; Jerónimo, C; Lind, GE; Lothe, RA; Morais, A; Oliveira, J; Patrício, P; Teixeira, MR | 1 |
Cronk, RJ; Lang, JM; McNeel, DG; Smith, HA | 1 |
Canter, DJ; Golovine, KV; Kolenko, VM; Kutikov, A; Makhov, PB; Matveev, VB; Roshchin, DA; Rybko, VA; Uzzo, RG | 1 |
Bianco-Miotto, T; Butler, LM; Centenera, MM; Chiam, K; Tilley, WD | 1 |
Carducci, MA; Herman, JG; Shabbeer, S; Simons, BW; Williams, SA | 1 |
Chen, CS; Huang, TH; Kuo, YC; Lai, IL; Lin, HY; Lin, SP; Niu, DM; Weng, YI | 1 |
Brooks, J; Jarrard, DF; Kobayashi, Y; Rajamanickam, V; Truong, M; Wagner, J; Yang, B | 1 |
Babiarova, K; Brabcova, E; Hainz, P; Krystofova, J; Kutinova, L; Musil, J; Nemeckova, S; Zurkova, K | 1 |
Chang, C; Huang, CK; Jiang, Q; Lai, KP; Lee, SO; Li, L; Liang, L; Lin, TH; Luo, J; Ma, Z; Niu, Y; Tian, J; Yamashita, S; Yeh, CR; Yeh, S | 1 |
Chang, C; Huang, CK; Lee, SO; Li, L; Liang, L; Luo, J; Niu, Y; Tian, J | 1 |
D'Alessandro, AM; Di Clemente, L; Di Pasquale, B; Dolo, V; Festuccia, C; Gravina, GL; Mancini, A; Marampon, F; Muzi, P; Ranieri, G | 1 |
Abildgaard, MO; Borre, M; Haldrup, C; Høyer, S; Kristensen, H; Parker, C; Strand, S; Sørensen, KD; Ulhøi, BP; Ørntoft, TF | 1 |
Gertych, A; Oh, JH; Tajbakhsh, J; Wawrowsky, KA; Weisenberger, DJ | 1 |
Durkin, ME; Popescu, NC; Yuan, BZ | 1 |
Carroll, P; Dahiya, R; Patra, A; Patra, SK; Zhao, H | 1 |
Hirokawa, Y; Matsuzaki, T; Shiraishi, T; Sugimura, Y; Suzuki, H; Takagi, A; Watanabe, M; Yamada, Y; Yamanaka, M; Yatani, R | 1 |
Dahiya, R; Igawa, M; Matsubara, A; Mita, K; Mutaguchi, K; Shiina, H; Usui, T; Yasumoto, H | 1 |
Hurtubise, A; Momparler, RL | 1 |
Assaly, M; Benz, A; Cerato, C; Desmond, JC; Greloz, V; Hermeking, H; Herrmann, F; Koeffler, HP; Lodygin, D; Mhawech, P; Schwaller, J | 1 |
Ekman, P; Fang, X; Liu, Z; Xu, D; Zheng, C | 1 |
Anast, JW; Bassett, WW; Carroll, PR; Dahiya, R; Enokida, H; Igawa, M; Kane, CJ; Kawahara, M; Kawakami, T; Li, LC; Nakagawa, M; Ogishima, T; Shiina, H; Terashima, M; Urakami, S; Verma, M | 1 |
Chen, JX; Cui, XY; Fu, PF; Wang, T | 1 |
Bassett, WW; Breault, JE; Dahiya, R; Enokida, H; Fujime, M; Igawa, M; Kawakami, T; Li, LC; Ogishima, T; Ribeiro-Filho, LA; Shiina, H; Tabatabai, L; Terashima, M; Urakami, S | 1 |
Pulukuri, SM; Rao, JS | 1 |
Carroll, P; Dahiya, R; Greene, KL; Igawa, M; Kane, CJ; Kishi, H; Li, LC; Shiina, H; Tanaka, Y; Zhao, H | 1 |
Jang, TL; Javonovic, B; Kim, SJ; Lee, C; Park, I; Pins, M; Rubenstein, JN; Yang, X; Zhang, Q | 1 |
Dahiya, R; Enokida, H; Igawa, M; Kawakami, T; Li, LC; Nonomura, N; Ogishima, T; Okino, ST; Okuyama, A; Shiina, H; Tanaka, Y; Tokizane, T; Urakami, S | 1 |
Brooks, JD; Kaygusuz, G; Kim, H; Lapointe, J; Li, C; Ong, DE; Pollack, JR; van de Rijn, M | 1 |
Flores-Morales, A; Johansson, B; Larsson, C; Nilsson, P; Norstedt, G; Pang, ST; Pourian, MR; Pousette, A; Weng, WH | 1 |
Chuang, JC; Jones, PA; Kwan, JM; Li, TW; Liang, G; Yang, AS; Yoo, CB | 1 |
Daignault, S; Day, ML; Imperiale, MJ; Low, JA; McCabe, MT; Wojno, KJ | 1 |
Ballman, KV; Cheville, JC; Lieber, MM; Morlan, BW; Neumann, RM; Tindall, DJ; Vanaja, DK; Young, CY | 1 |
Guan, M; Popescu, NC; Soulitzis, N; Spandidos, DA; Zhou, X | 1 |
Catto, JW; Cross, SS; Hamdy, FC; Leiblich, A; Leung, HY; Phillips, JT; Rehman, I | 1 |
Berenguer, J; Borczuk, AC; Hei, TK; Powell, CA; Shao, G; Zhao, Y | 1 |
Diamandis, EP; Pampalakis, G; Sotiropoulou, G | 1 |
Das, PM; Ferdinand, L; Gopisetty, G; Ramachandran, K; Reis, IM; Singal, R; Vanwert, J | 1 |
Dahiya, R; Igawa, M; Li, LC; Okino, ST; Pookot, D; Shiina, H; Urakami, S; Zhao, H | 1 |
Carvalho, AL; Cerveira, N; Costa, VL; Henrique, R; Hoque, MO; Jerónimo, C; Oliveira, J; Ribeiro, FR; Sidransky, D; Teixeira, MR | 1 |
Euhus, DM; Fong, KM; Gao, B; Gazdar, AF; Gerald, W; Girard, L; Jiang, A; Kim, YH; Lam, CL; Lewis, CM; Minna, JD; Nanda, R; Olopade, OI; Perou, CM; Pollack, JR; Sato, M; Shames, DS; Shay, JW; Shivapurkar, N; Shyr, Y; Wong, M | 1 |
Day, ML; Gschwend, JE; Kuefer, R; McCabe, MT; Wojno, KJ; Zorn, CS | 1 |
Ekström, L; Gustafsson, O; Morfin, R; Olsson, M; Rane, A; Rietz, BD; Skogastierna, C; Tolf, A | 1 |
Engers, R; Hader, C; Hoffmann, MJ; Jung, V; Müller, M; Schulz, WA; Wlazlinski, A | 1 |
Dubovsky, JA; McNeel, DG | 1 |
Bishop, MC; Li, G; McArdle, SE; Rees, RC; Seth, R; Walton, TJ | 1 |
Aparicio, A; Asmar, L; Berry, WR; Boehm, KA; Guttierez, I; Hutson, TE; Sonpavde, G; von Hoff, DD | 1 |
Ethier, SP; Hanifi-Moghaddam, P; Hollestelle, A; Klijn, JG; Merajver, SD; Schutte, M; van den Ouweland, A; Wasielewski, M | 1 |
Bologna, M; de Vito, M; Dolo, V; Festuccia, C; Gravina, GL; Millimaggi, D; Tombolini, V; Vicentini, C | 1 |
Hosoya, K; McDonell, N; Niwa, T; Shirai, T; Takahashi, S; Tsujino, Y; Ushijima, T; Watanabe, N; Yamashita, S | 1 |
Dahiya, R; Hirata, H; Igawa, M; Kawamoto, K; Kikuno, N; Majid, S; Shiina, H; Tanaka, Y; Urakami, S | 1 |
Baylin, SB; Bova, GS; Cairns, P; Ewing, CM; Herman, JG; Isaacs, WB; Jarrard, DF; Nguyen, SH; Pin, SS; Sidransky, D | 1 |
Isaacs, WB; Reiter, RE; Said, JW; Sawyers, CL; Suzuki, H; Tran, C; Vessella, RL; Whang, YE; Wu, X | 1 |
el Yaagoubi, M; Khalid, A; Siest, G; Visvikis, A; Wellman, M | 1 |
Chi, SG; deVere White, RW; Gumerlock, PH; Muenzer, JT | 1 |
Romijn, JC; Trapman, J; Van der Kwast, TH; Van Steenbrugge, GJ; Verkaik, NS | 1 |
Dritschilo, A; Prasad, SC; Soldatenkov, VA; Thraves, PJ; Varghese, S | 1 |
Lu, Y; Steiner, MS; Wang, Y; Zhang, X; Zhang, Y | 1 |
Janeczko, M; Lee, WH; Nanus, DM; Nelson, JB; Nelson, WG; Papandreou, CN; Shen, R; Usmani, BA | 1 |
Inoue, M; Kanaya, T; Kitagawa, Y; Koshida, K; Kyo, S; Namiki, M; Takakura, M | 1 |
Hirokawa, Y; Ito, H; Mizokami, A; Nakayama, T; Sekita, N; Shiraishi, T; Suzuki, H; Toyota, M; Watanabe, M; Yatani, R | 1 |
Bashambu, M; Singal, R; van Wert, J | 1 |
Dahiya, R; Patra, A; Patra, SK | 1 |
Fischer, J; Florl, AR; Maas, S; Müller, W; Pulte, T; Santourlidis, S; Schulz, WA; Warskulat, U | 1 |
Akakura, K; Ichikawa, T; Igarashi, T; Ito, H; Kito, H; Nakayama, T; Sekita, N; Shiraishi, T; Suzuki, H; Toyota, M; Watanabe, M; Yoshie, O | 1 |
Dahiya, R; Dharia, A; Li, LC; Nojima, D; Perinchery, G; Ribeiro-Filho, L; Yen, TS | 1 |
Dahiya, R; Dasari, VK; Deng, D; Perinchery, G; Yeh, CC | 1 |
Lieberman, AP; Ware, JL; Webb, KS | 1 |
Ware, JL | 1 |
2 review(s) available for azacitidine and Prostatic Neoplasms
Article | Year |
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Epigenetic therapy in urologic cancers: an update on clinical trials.
Topics: Azacitidine; Clinical Trials as Topic; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Enzyme Inhibitors; Humans; Male; Prostatic Neoplasms | 2017 |
Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716.
Topics: Anemia, Sickle Cell; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Decitabine; Humans; Leukemia; Lung Neoplasms; Male; Prostatic Neoplasms | 2003 |
1 trial(s) available for azacitidine and Prostatic Neoplasms
Article | Year |
---|---|
Phase II study of azacitidine to restore responsiveness of prostate cancer to hormonal therapy.
Topics: Androgen Antagonists; Antimetabolites, Antineoplastic; Azacitidine; Humans; Male; Prostatic Neoplasms | 2007 |
132 other study(ies) available for azacitidine and Prostatic Neoplasms
Article | Year |
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SPOP mutation induces DNA methylation via stabilizing GLP/G9a.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Docetaxel; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Male; Mice; Mutation; Nuclear Proteins; Prostatic Neoplasms; Protein Stability; Proteolysis; Repressor Proteins; Xenograft Model Antitumor Assays | 2021 |
Targeting of the Interleukin-13 Receptor (IL-13R)α2 Expressing Prostate Cancer by a Novel Hybrid Lytic Peptide.
Topics: Antineoplastic Agents; Azacitidine; Humans; Interleukin-13 Receptor alpha2 Subunit; Male; Peptides; Prostatic Neoplasms | 2023 |
Demethylation of miR-195 suppresses prostate cancer cell proliferation, migration and invasion.
Topics: Apoptosis; Azacitidine; Cell Movement; Cell Proliferation; CpG Islands; Demethylation; DNA Methylation; Down-Regulation; Epithelial-Mesenchymal Transition; Genes, Tumor Suppressor; Humans; Male; MicroRNAs; Neoplasm Invasiveness; PC-3 Cells; Promoter Regions, Genetic; Prostatic Neoplasms; Signal Transduction; Transfection | 2020 |
Characterization of the prognostic values and response to immunotherapy/chemotherapy of Krüppel-like factors in prostate cancer.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cohort Studies; Disease-Free Survival; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Immunotherapy; Kruppel-Like Transcription Factors; Male; Multivariate Analysis; Prognosis; Promoter Regions, Genetic; Prostatic Neoplasms; Reproducibility of Results | 2020 |
Evaluation of combination protocols of the chemotherapeutic agent FX-9 with azacitidine, dichloroacetic acid, doxorubicin or carboplatin on prostate carcinoma cell lines.
Topics: Androgens; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Carboplatin; Cell Count; Cell Line, Tumor; Cell Survival; Dichloroacetic Acid; Doxorubicin; Drug Synergism; Humans; Isoquinolines; Male; Prostatic Neoplasms | 2021 |
MODULATION OF ANTITUMOR IMMUNE RESPONSE IN MOUSE PROSTATE CANCER MODEL.
Topics: Animals; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Cell Proliferation; Dendritic Cells; Immunologic Factors; Interleukin-12; Interleukin-15; Lenalidomide; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Prostatic Neoplasms; Thalidomide | 2017 |
Hypermethylation of the SPARC promoter and its prognostic value for prostate cancer.
Topics: Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Grading; Osteonectin; Prognosis; Promoter Regions, Genetic; Prostatic Neoplasms; Survival Analysis | 2018 |
MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis.
Topics: Aged; Azacitidine; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cohort Studies; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Regulatory Networks; Humans; Male; MicroRNAs; Middle Aged; Phenotype; Promoter Regions, Genetic; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-myc; Response Elements; RNA, Messenger; Signal Transduction; Up-Regulation | 2018 |
Combinatorial strategy of epigenetic and hormonal therapies: A novel promising approach for treating advanced prostate cancer.
Topics: Anticarcinogenic Agents; Azacitidine; beta Catenin; Caspase 3; Cell Proliferation; Cyclin D1; Decitabine; Disease Progression; Epigenesis, Genetic; Estrogen Receptor beta; Hormones; Humans; Hydroxamic Acids; Male; Methylation; Nitriles; Propionates; Prostate; Prostatic Neoplasms; Vascular Endothelial Growth Factor A | 2018 |
DNA methylation changes following DNA damage in prostate cancer cells.
Topics: Azacitidine; BRCA1 Protein; Cell Line, Tumor; CpG Islands; DNA Damage; DNA Methylation; Epigenesis, Genetic; High-Throughput Nucleotide Sequencing; Humans; Male; PC-3 Cells; Phosphorylation; Prostatic Neoplasms; Radiation Tolerance; Sequence Analysis, DNA | 2019 |
Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer.
Topics: Adenocarcinoma; Aged; Azacitidine; Case-Control Studies; Cell Line, Tumor; Conserved Sequence; Decitabine; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation, Neoplastic; Genome, Human; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Metribolone; Middle Aged; Oligonucleotide Array Sequence Analysis; Prostate; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; RNA, Untranslated; Testosterone Congeners; Transcriptome | 2013 |
Analysis of promoter non-CG methylation in prostate cancer.
Topics: Azacitidine; Carrier Proteins; CpG Islands; Cytoskeletal Proteins; DNA Methylation; Homeodomain Proteins; Humans; Male; Methyltransferases; Promoter Regions, Genetic; Prostatic Neoplasms | 2013 |
Deregulated expression of urokinase and its inhibitor type 1 in prostate cancer cells: role of epigenetic mechanisms.
Topics: Adenocarcinoma; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA, Neoplasm; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Neoplasm Invasiveness; Plasminogen Activator Inhibitor 1; Prostate; Prostatic Neoplasms; Urokinase-Type Plasminogen Activator | 2013 |
Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cluster Analysis; CpG Islands; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Grading; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Reproducibility of Results; Sequence Analysis, DNA | 2013 |
Epigenetic modifications of prostate-derived Ets transcription factor in breast cancer cells.
Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; DNA Methylation; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Humans; Male; MCF-7 Cells; Prostatic Neoplasms; Proto-Oncogene Proteins c-ets | 2013 |
Aberrant expression of the PRAC gene in prostate cancer.
Topics: Androgen Antagonists; Androgens; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; Dihydrotestosterone; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Nuclear Proteins; Prostatic Neoplasms | 2013 |
Androgen receptor is negatively correlated with the methylation-mediated transcriptional repression of miR-375 in human prostate cancer cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; RNA Interference; RNA, Small Interfering; Transcriptional Activation | 2014 |
Epigenetic regulation of MDR1 gene through post-translational histone modifications in prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Cell Line, Tumor; CpG Islands; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Promoter Regions, Genetic; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Protein Processing, Post-Translational | 2013 |
miR-199a-3p inhibits aurora kinase A and attenuates prostate cancer growth: new avenue for prostate cancer treatment.
Topics: Animals; Apoptosis; Aurora Kinase A; Azacitidine; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Luminescence; Male; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Prostatic Neoplasms; Protein Binding; RNA, Messenger | 2014 |
Comparative effects of soy phytoestrogens and 17β-estradiol on DNA methylation of a panel of 24 genes in prostate cancer cell lines.
Topics: Azacitidine; Budesonide; Cell Line, Tumor; DNA Methylation; Estradiol; Estrogen Receptor beta; Gene Expression Regulation, Neoplastic; Genistein; Glycine max; Humans; Isoflavones; Male; Phytoestrogens; Promoter Regions, Genetic; Prostatic Neoplasms | 2014 |
Methylation of the PMEPA1 gene, a negative regulator of the androgen receptor in prostate cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Black or African American; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Gene Expression; Humans; Introns; Male; Membrane Proteins; Middle Aged; Molecular Sequence Data; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; White People | 2014 |
Novel epigenetic target therapy for prostate cancer: a preclinical study.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Chromatography, High Pressure Liquid; Decitabine; Epigenesis, Genetic; Humans; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Prostatic Neoplasms | 2014 |
Examination of the regulation of galectin-3 expression in cancer.
Topics: Azacitidine; Blotting, Western; Cell Line, Tumor; Cloning, Molecular; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Galectin 3; Gene Expression Regulation, Neoplastic; Humans; Male; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Transcriptional Activation | 2015 |
Methylation of Integrin α4 and E-Cadherin Genes in Human Prostate Cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Cadherins; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Integrin alpha4; Male; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2015 |
Genome-wide DNA methylation modified by soy phytoestrogens: role for epigenetic therapeutics in prostate cancer?
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Budesonide; Cell Line, Tumor; Cell Proliferation; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genistein; Glycine max; Humans; Isoflavones; Male; Oligonucleotide Array Sequence Analysis; Phytoestrogens; Prostatic Neoplasms | 2015 |
Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Black or African American; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Genome, Human; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Organ Specificity; Promoter Regions, Genetic; Prostatic Neoplasms; White People | 2015 |
Adiponectin as a potential tumor suppressor inhibiting epithelial-to-mesenchymal transition but frequently silenced in prostate cancer by promoter methylation.
Topics: Adiponectin; Aged; Antimetabolites, Antineoplastic; Azacitidine; Cell Proliferation; China; DNA Methylation; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Male; Neoplasm Grading; Promoter Regions, Genetic; Prostate; Prostatectomy; Prostatic Hyperplasia; Prostatic Neoplasms; Tumor Cells, Cultured | 2015 |
The androgen receptor plays a suppressive role in epithelial- mesenchymal transition of human prostate cancer stem progenitor cells.
Topics: Azacitidine; Cell Line, Tumor; Cell Self Renewal; Chromans; Chromones; Decitabine; Drug Synergism; Epithelial-Mesenchymal Transition; Humans; Male; Morpholines; Neoplastic Stem Cells; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Vitamin E | 2015 |
Methylation-induced silencing of miR-34a enhances chemoresistance by directly upregulating ATG4B-induced autophagy through AMPK/mTOR pathway in prostate cancer.
Topics: 3' Untranslated Regions; AMP-Activated Protein Kinases; Autophagy; Autophagy-Related Proteins; Azacitidine; Cell Line, Tumor; Cysteine Endopeptidases; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Humans; Male; MicroRNAs; Prostatic Neoplasms; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Correlation between the germline methylation status in ERβ promoter and the risk in prostate cancer: a prospective study.
Topics: Aged; Aged, 80 and over; Azacitidine; Case-Control Studies; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor beta; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Promoter Regions, Genetic; Prospective Studies; Prostatic Neoplasms | 2016 |
The transcribed-ultraconserved regions in prostate and gastric cancer: DNA hypermethylation and microRNA-associated regulation.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Cell Proliferation; Conserved Sequence; DNA Methylation; DNA, Neoplasm; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Middle Aged; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms | 2016 |
Role of DNA Methylation in Cabazitaxel Resistance in Prostate Cancer.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Survival; DNA Methylation; DNA Modification Methylases; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Taxoids; Time Factors | 2016 |
Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer.
Topics: Aged; Aged, 80 and over; Apoptosis; Azacitidine; Cell Line, Tumor; CpG Islands; Cytochrome P-450 CYP1A1; Decitabine; DNA Methylation; Enhancer Elements, Genetic; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Sulfites; Tissue Array Analysis; Tobacco Smoking; Xenobiotics | 2016 |
Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Flavins; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nerve Tissue Proteins; Prostatic Neoplasms; Pteridines; Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction; Transplantation, Heterologous | 2016 |
Secreted Protein Acidic and Rich in Cysteine (SPARC) Mediates Metastatic Dormancy of Prostate Cancer in Bone.
Topics: Animals; Azacitidine; Bone Morphogenetic Protein 7; Bone Neoplasms; Cell Line, Tumor; DNA Methylation; DNA, Neoplasm; Humans; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Osteonectin; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Prostatic Neoplasms; Tumor Microenvironment | 2016 |
Sex steroid-induced DNA methylation changes and inflammation response in prostate cancer.
Topics: Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Chemokine CXCL5; Chemokines, CC; Cytokines; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Hydroxamic Acids; Inflammation; Interleukin-5; Male; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Neoplasms; Tissue Array Analysis; Tumor Cells, Cultured | 2016 |
Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer.
Topics: Acetylation; Animals; Antineoplastic Agents; Azacitidine; Cell Death; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Docetaxel; Epigenesis, Genetic; HEK293 Cells; Histones; Humans; Hydroxamic Acids; Kidney; Male; Methylation; Neoplasms; Oligopeptides; Prostatic Neoplasms; Rats; Taxoids | 2016 |
Inducible expression of cancer-testis antigens in human prostate cancer.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Indoles; Male; Membrane Proteins; Neoplasm Proteins; Neoplastic Cells, Circulating; Panobinostat; Prostatic Neoplasms; Repressor Proteins; Testis | 2016 |
Testis specific Y-like 5: gene expression, methylation and implications for drug sensitivity in prostate carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Grading; Nuclear Proteins; Promoter Regions, Genetic; Prostatic Neoplasms; Signal Transduction | 2017 |
ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer.
Topics: Adenocarcinoma; Aged; Azacitidine; Base Sequence; Biomarkers, Tumor; Cell Cycle; Cell Proliferation; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Molecular Sequence Data; Neoplasm Staging; Prostatic Hyperplasia; Prostatic Neoplasms; Tumor Cells, Cultured | 2008 |
Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells.
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Prostatic Neoplasms; Receptors, Somatostatin; RNA, Messenger; Somatostatin; Up-Regulation | 2008 |
Downmodulation of dimethyl transferase activity enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in prostate cancer cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Caspase 8; Cell Line, Tumor; Cell Proliferation; Decitabine; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Male; Prostatic Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand | 2008 |
Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients.
Topics: Alleles; Azacitidine; Cells, Cultured; DNA Replication; Genomic Imprinting; Humans; Lymphocytes; Male; Prostatic Neoplasms; Retinoblastoma Protein; snRNP Core Proteins | 2008 |
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.
Topics: Antineoplastic Agents; Azacitidine; Calcium-Binding Proteins; Cell Line, Tumor; Decitabine; EGF Family of Proteins; Endothelial Growth Factors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Male; MicroRNAs; Neoplasms; Phenylbutyrates; Promoter Regions, Genetic; Prostatic Neoplasms; Up-Regulation; Urinary Bladder Neoplasms | 2009 |
Azacitidine improves antitumor effects of docetaxel and cisplatin in aggressive prostate cancer models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Proliferation; Cisplatin; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; Docetaxel; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Humans; Male; Mice; Mice, Nude; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Taxoids; Xenograft Model Antitumor Assays | 2009 |
Synergy of 5-aza-2'-deoxycytidine (DAC) and paclitaxel in both androgen-dependent and -independent prostate cancer cell lines.
Topics: Androgens; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Decitabine; Flow Cytometry; Humans; Male; Mitochondria; Oxidoreductases; Paclitaxel; Prostatic Neoplasms; Tetrazolium Salts; Up-Regulation | 2009 |
Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target.
Topics: Antineoplastic Agents; Azacitidine; Cell Cycle Proteins; Cell Line, Tumor; DNA Methylation; DNA Primers; DNA, Neoplasm; Docetaxel; Gene Expression Regulation, Neoplastic; Genome; Humans; Male; Methylation; Nuclear Proteins; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Taxoids; Up-Regulation | 2009 |
Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Bone Morphogenetic Protein 7; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression; Gene Silencing; Genes, Tumor Suppressor; Genetic Markers; Homeodomain Proteins; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Transcription Factors | 2009 |
CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Cell Adhesion; Cell Movement; Cell Proliferation; Collagen; Collagen Type I; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoenzyme Techniques; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms | 2009 |
Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Drug Combinations; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Glutathione Transferase; Hydroxamic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Prostate; Prostatic Neoplasms; RNA, Messenger | 2009 |
Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer.
Topics: Acetylation; Animals; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin; Cystatin M; Decitabine; Disease Progression; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasms, Experimental; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transplantation, Heterologous | 2009 |
Epigenetic modulation of PTEN expression during antiandrogenic therapies in human prostate cancer.
Topics: Androgen Antagonists; Apoptosis; Azacitidine; Blotting, Western; Cells, Cultured; Epigenesis, Genetic; Gene Expression; Humans; Male; Polymerase Chain Reaction; Prostatic Neoplasms; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Valproic Acid | 2009 |
Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells.
Topics: Androgens; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Docetaxel; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Male; Neoplasm Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Messenger; Taxoids | 2010 |
Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice.
Topics: Animals; Azacitidine; CpG Islands; DNA Methylation; Epigenesis, Genetic; Male; Mice; NF-E2-Related Factor 2; Prostatic Neoplasms; Receptors, Tumor Necrosis Factor, Member 25; Transcription, Genetic; Trichosanthin | 2010 |
Establishment and characterization of multi-drug resistant, prostate carcinoma-initiating stem-like cells from human prostate cancer cell lines 22RV1.
Topics: Acetylation; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epigenesis, Genetic; Histones; Humans; Male; Methylation; Mice; Mice, Nude; Neoplasm Proteins; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-kit; Time Factors; Tumor Burden | 2010 |
5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Humans; Male; Mice; Mice, Nude; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Tosyl Compounds | 2010 |
Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene.
Topics: Androgen Antagonists; Androgens; Azacitidine; Blotting, Western; CpG Islands; Decitabine; Dihydrotestosterone; Disease Progression; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Promoter Regions, Genetic; Prostatic Neoplasms; Receptor, IGF Type 1; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2010 |
Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b.
Topics: Azacitidine; Cadherins; Cell Communication; Cell Line, Tumor; Cell Movement; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Genes, ras; Humans; Male; Promoter Regions, Genetic; Prostatic Neoplasms | 2010 |
Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells.
Topics: Adenocarcinoma; Azacitidine; Base Sequence; Cell Line, Tumor; Cell Movement; Chemokines, CXC; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Sequence Data; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Messenger | 2010 |
Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer.
Topics: Azacitidine; Calcitriol; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Steroid Hydroxylases; Vitamin D3 24-Hydroxylase | 2010 |
The functional significance of microRNA-145 in prostate cancer.
Topics: Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Gene Silencing; Genistein; Humans; Hydroxamic Acids; Male; Microarray Analysis; MicroRNAs; Prostatic Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2010 |
Quantitative assessment of AKAP12 promoter methylation in human prostate cancer using methylation-sensitive high-resolution melting: correlation with Gleason score.
Topics: A Kinase Anchor Proteins; Azacitidine; Cell Cycle Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Humans; Male; Mitogens; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Drug Resistance, Neoplasm; E2F6 Transcription Factor; Humans; Male; Mice; MicroRNAs; Promoter Regions, Genetic; Prostatic Neoplasms | 2010 |
Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth.
Topics: Androgens; Animals; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Epigenomics; Epithelial Cells; HEK293 Cells; Humans; Male; Mice; Mice, Nude; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; Receptors, Androgen; Receptors, G-Protein-Coupled; RGS Proteins; RNA, Small Interfering | 2012 |
EFEMP1 as a novel DNA methylation marker for prostate cancer: array-based DNA methylation and expression profiling.
Topics: Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenomics; Extracellular Matrix Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Reproducibility of Results | 2011 |
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Cadherins; Carcinoma, Renal Cell; Case-Control Studies; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Male; Middle Aged; Promoter Regions, Genetic; Prostatic Neoplasms; ROC Curve; Sensitivity and Specificity; Urinary Bladder Neoplasms | 2011 |
Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Cancer Vaccines; Cell Line, Tumor; Decitabine; Epitopes; Female; Gene Expression Regulation, Neoplastic; HLA-A2 Antigen; HLA-DR1 Antigen; Humans; Immunotherapy; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Molecular Targeted Therapy; Multigene Family; Neoplasm Metastasis; Neoplasm Proteins; Prostatic Neoplasms; Repressor Proteins; Sequence Alignment; Sequence Homology, Amino Acid; T-Cell Antigen Receptor Specificity | 2011 |
Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells.
Topics: Azacitidine; Base Sequence; Cation Transport Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Primers; Epigenesis, Genetic; Gene Silencing; Humans; Male; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-2; Transcription, Genetic; Zinc | 2011 |
GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.
Topics: Azacitidine; Biomarkers, Tumor; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytidine; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Humans; Male; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors | 2011 |
Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Choline; Decitabine; Diet; Disease Progression; DNA Methylation; Folic Acid; Homocysteine; Humans; Male; Methionine; Mice; Mice, Nude; Prostatic Neoplasms; Tumor Cells, Cultured; Vitamin B 6 | 2012 |
Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Decitabine; Deoxyglucose; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Male; Prostate; Prostatic Neoplasms; Transcriptional Activation | 2012 |
Even-skipped homeobox 1 is frequently hypermethylated in prostate cancer and predicts PSA recurrence.
Topics: Azacitidine; Cell Line, Tumor; Disease-Free Survival; DNA Methylation; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Homeodomain Proteins; Humans; Hydroxamic Acids; Male; Prognosis; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Recurrence | 2012 |
Immunization with WT1-derived peptides by tattooing inhibits the growth of TRAMP-C2 prostate tumor in mice.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Azacitidine; Cancer Vaccines; Cell Line, Tumor; Decitabine; Injections, Intradermal; Male; Mice; Mice, Inbred BALB C; Poly I-C; Prostatic Neoplasms; Tattooing; Transforming Growth Factor beta; Vaccines, Subunit; WT1 Proteins | 2012 |
New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells.
Topics: Animals; Azacitidine; Curcumin; Decitabine; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Neoplastic Stem Cells; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Xenograft Model Antitumor Assays | 2013 |
Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; Transplantation, Heterologous | 2012 |
Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinogenesis; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Epithelial Cells; Gene Expression; Glutathione S-Transferase pi; Humans; Male; Phenotype; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms | 2013 |
Prognostic significance of aberrantly silenced ANPEP expression in prostate cancer.
Topics: Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; CD13 Antigens; Cell Line, Tumor; Decitabine; Disease-Free Survival; DNA Methylation; Epigenesis, Genetic; Gene Silencing; Humans; Male; Middle Aged; Neovascularization, Pathologic; Promoter Regions, Genetic; Prostatectomy; Prostatic Neoplasms; Sequence Analysis, DNA | 2013 |
3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Survival; Cytidine; DNA Methylation; Humans; Liver Neoplasms; Male; Phenotype; Prostatic Neoplasms | 2013 |
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers.
Topics: Adenocarcinoma; Azacitidine; Base Sequence; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; GTPase-Activating Proteins; Humans; Liver Neoplasms; Male; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Promoter Regions, Genetic; Prostatic Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Methyl-CpG-DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2.
Topics: Amino Acid Sequence; Antineoplastic Agents; Azacitidine; Cell Line; Chromosomal Proteins, Non-Histone; CpG Islands; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Leupeptins; Male; Methyl-CpG-Binding Protein 2; Prostatic Neoplasms; Repressor Proteins; RNA, Messenger; Transcription Factors | 2003 |
Aberrant methylation of the vascular endothelial growth factor receptor-1 gene in prostate cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Sulfites; Tumor Cells, Cultured; Vascular Endothelial Growth Factor Receptor-1 | 2003 |
Restoration of insulin-like growth factor binding protein-related protein 1 has a tumor-suppressive activity through induction of apoptosis in human prostate cancer.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Caspase 3; Caspases; Cell Division; Cell Line, Tumor; Culture Media, Conditioned; Decitabine; DNA, Complementary; Humans; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Male; Prostatic Neoplasms; RNA, Messenger; Transfection | 2003 |
Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cadherins; Cell Line, Tumor; Decitabine; DNA; Docetaxel; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Male; Prostatic Neoplasms; Proteins; Serpins; Taxoids; Time Factors | 2004 |
Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation.
Topics: 14-3-3 Proteins; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; CpG Islands; DNA Methylation; Down-Regulation; Endometrial Neoplasms; Exonucleases; Exoribonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mutation; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; RNA, Messenger; Tissue Array Analysis; Tumor Suppressor Protein p53 | 2005 |
Enhanced sensitivity of prostate cancer DU145 cells to cisplatinum by 5-aza-2'-deoxycytidine.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Line, Tumor; Cisplatin; Decitabine; DNA Methylation; Drug Synergism; Flow Cytometry; Humans; Male; Microscopy, Fluorescence; Prostatic Neoplasms; Time Factors | 2004 |
CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancer.
Topics: Aged; Aged, 80 and over; Apoptosis; Azacitidine; Base Sequence; Cell Division; CpG Islands; Decitabine; Disease Progression; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, MDR; Humans; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines.
Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Female; Humans; Male; Nerve Tissue Proteins; Prostatic Neoplasms; RNA, Messenger; Stomach Neoplasms | 2004 |
Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer.
Topics: Aged; Aged, 80 and over; Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronidase; Humans; Immediate-Early Proteins; Male; Middle Aged; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Transcription Factors; Up-Regulation | 2005 |
Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Cycle Proteins; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA Damage; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Male; Prostatic Neoplasms; Signal Transduction; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2005 |
CpG methylation at promoter site -140 inactivates TGFbeta2 receptor gene in prostate cancer.
Topics: Azacitidine; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Tumor Cells, Cultured | 2005 |
Insensitivity to transforming growth factor-beta results from promoter methylation of cognate receptors in human prostate cancer cells (LNCaP).
Topics: Azacitidine; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; Humans; Male; Phosphorylation; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Tumor Cells, Cultured; Up-Regulation | 2005 |
Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Azacitidine; Cell Line, Tumor; Cytochrome P-450 CYP1B1; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Azacitidine; Base Sequence; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Isoenzymes; Male; Molecular Sequence Data; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; Retinal Dehydrogenase; Tretinoin | 2005 |
Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer.
Topics: Androgens; Azacitidine; Cell Line, Tumor; Chromosome Aberrations; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 2; Decitabine; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Methyltransferases; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Spectral Karyotyping | 2006 |
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer.
Topics: Animals; Antigens, Viral, Tumor; Antimetabolites, Antineoplastic; Azacitidine; Cell Growth Processes; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Humans; Male; Mice; Mice, Inbred C57BL; Prostate; Prostatic Neoplasms; Transgenes | 2006 |
PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer.
Topics: Aged; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cyclooxygenase 2; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Humans; LIM Domain Proteins; Male; Membrane Proteins; Microfilament Proteins; Middle Aged; Nerve Tissue Proteins; Polymerase Chain Reaction; Prostatic Neoplasms | 2006 |
Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications.
Topics: Acetylation; Adult; Aged; Aged, 80 and over; Azacitidine; Base Sequence; Blotting, Southern; Blotting, Western; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Gene Deletion; GTPase-Activating Proteins; Humans; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2006 |
Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer.
Topics: Amino Acid Sequence; Azacitidine; Base Sequence; Bone Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Isoenzymes; L-Lactate Dehydrogenase; Male; Molecular Sequence Data; Promoter Regions, Genetic; Prostatic Neoplasms; Proteomics; Tumor Cells, Cultured | 2006 |
Epigenetic inactivation of Betaig-h3 gene in human cancer cells.
Topics: Azacitidine; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Luciferases; Lung Neoplasms; Male; Neoplasms; Promoter Regions, Genetic; Prostatic Neoplasms; Transforming Growth Factor beta | 2006 |
The epigenetic basis for the aberrant expression of kallikreins in human cancers.
Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Male; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms | 2006 |
Methylation mediated silencing of TMS1/ASC gene in prostate cancer.
Topics: Aged; Aged, 80 and over; Azacitidine; CARD Signaling Adaptor Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Cytoskeletal Proteins; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Middle Aged; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Epigenetic inactivation of the dioxin-responsive cytochrome P4501A1 gene in human prostate cancer.
Topics: Azacitidine; Chromatin; CpG Islands; Cytochrome P-450 CYP1A1; Decitabine; Dioxins; DNA Methylation; DNA, Neoplasm; Enhancer Elements, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Prostatic Neoplasms; Response Elements | 2006 |
Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.
Topics: Adenocarcinoma; Adult; Aged; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; Cyclin D2; Cyclins; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 2006 |
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Cathepsin K; Cathepsins; Colonic Neoplasms; CpG Islands; Cyclin A; Cyclin A1; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Profiling; Humans; Lung Neoplasms; Male; Middle Aged; MSX1 Transcription Factor; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Transcription Factors; Tumor Cells, Cultured | 2006 |
5-aza-2'-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azacitidine; Castration; Combined Modality Therapy; Decitabine; Disease Models, Animal; Male; Mice; Mice, Transgenic; Neoplasms, Hormone-Dependent; Prostatic Neoplasms | 2007 |
Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma.
Topics: Adenocarcinoma; Aged; Azacitidine; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 7; Decitabine; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor beta; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Steroid Hydroxylases | 2007 |
Downregulation of several fibulin genes in prostate cancer.
Topics: Aged; Azacitidine; Calcium-Binding Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Extracellular Matrix Proteins; Gene Dosage; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Prostatic Neoplasms; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Neoplasm; Antibody Specificity; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoglobulin G; Male; Membrane Proteins; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines.
Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Estrogen Receptor alpha; Estrogen Receptor beta; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Receptors, Progesterone | 2008 |
Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.
Topics: Azacitidine; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Checkpoint Kinase 2; Codon, Nonsense; Colorectal Neoplasms; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, cdc; Genes, p53; Humans; Male; Neoplasm Proteins; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2009 |
Chronic azacitidine treatment results in differentiating effects, sensitizes against bicalutamide in androgen-independent prostate cancer cells.
Topics: Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Cell Survival; Gene Silencing; Humans; Male; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Repressor Proteins; RNA, Small Interfering; Tosyl Compounds | 2008 |
Methylation silencing of transforming growth factor-beta receptor type II in rat prostate cancers.
Topics: Adenocarcinoma; Animals; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Up-Regulation | 2008 |
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells.
Topics: Acetylation; Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Chromones; CpG Islands; Decitabine; Deubiquitinating Enzyme CYLD; Down-Regulation; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, Tumor Suppressor; Genistein; Histones; Humans; Hydroxamic Acids; Male; Methylation; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phytoestrogens; Prostatic Neoplasms; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Sirtuins; Tumor Suppressor Proteins; Up-Regulation | 2008 |
Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer.
Topics: Aged; Azacitidine; Carrier Proteins; Chromosome Deletion; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; DNA, Neoplasm; Gene Expression; Heterozygote; Humans; Male; Middle Aged; Neoplasm Metastasis; Polymerase Chain Reaction; Prostatic Neoplasms; Sequence Analysis, DNA; Tumor Cells, Cultured | 1997 |
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression.
Topics: Azacitidine; Cell Compartmentation; Cytoplasm; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Male; Mutation; Neoplasm Transplantation; Phosphoric Monoester Hydrolases; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Tyrosine Phosphatases; PTEN Phosphohydrolase; RNA, Messenger; RNA, Neoplasm; Sequence Deletion; Transplantation, Heterologous; Tumor Suppressor Proteins | 1998 |
5-Azacytidine modulates gamma-glutamyltransferase and glutathione levels in two human prostatic adenocarcinoma cell lines.
Topics: Adenocarcinoma; Azacitidine; Blotting, Southern; DNA Methylation; DNA, Neoplasm; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Liver; Male; Placenta; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1998 |
Frequent alteration of CDKN2 (p16(INK4A)/MTS1) expression in human primary prostate carcinomas.
Topics: Adenocarcinoma; Animals; Azacitidine; Blotting, Western; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, Retinoblastoma; Humans; Male; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Prostatic Hyperplasia; Prostatic Neoplasms; Retinoblastoma Protein; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Down-regulation of CD44 expression in human prostatic carcinoma cell lines is correlated with DNA hypermethylation.
Topics: Antimetabolites, Antineoplastic; Azacitidine; CpG Islands; DNA Methylation; DNA, Neoplasm; Down-Regulation; Humans; Hyaluronan Receptors; Male; Neoplasm Proteins; Prostatic Neoplasms; RNA, Messenger; Tumor Cells, Cultured | 1999 |
Differential expression of stathmin during neoplastic conversion of human prostate epithelial cells is reversed by hypomethylating agent, 5-azacytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; DNA Methylation; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Gene Expression; Humans; Male; Microtubule Proteins; Phosphoproteins; Phosphorylation; Prostate; Prostatic Neoplasms; Stathmin; Tumor Cells, Cultured | 1999 |
p16/MTS1/INK4A suppresses prostate cancer by both pRb dependent and independent pathways.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Division; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Retinoblastoma Protein | 2000 |
Methylation of the neutral endopeptidase gene promoter in human prostate cancers.
Topics: Azacitidine; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Male; Neprilysin; Promoter Regions, Genetic; Prostatic Neoplasms; Tumor Cells, Cultured | 2000 |
Demethylating reagent 5-azacytidine inhibits telomerase activity in human prostate cancer cells through transcriptional repression of hTERT.
Topics: Azacitidine; Catalytic Domain; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Male; Prostatic Neoplasms; RNA; Telomerase; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2000 |
Epigenetic regulation of androgen receptor gene expression in human prostate cancers.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Binding Sites; Cyclic AMP Response Element-Binding Protein; Decitabine; Dinucleoside Phosphates; DNA Methylation; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; Tumor Cells, Cultured | 2000 |
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells.
Topics: Azacitidine; Base Sequence; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Glutathione Transferase; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Isoenzymes; Male; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Prostatic Neoplasms; Transfection; Tumor Cells, Cultured | 2001 |
Histone deacetylase and DNA methyltransferase in human prostate cancer.
Topics: Azacitidine; Cell Line; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Histone Deacetylases; Humans; Immunohistochemistry; Male; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Fluorescence; Tumor Cells, Cultured; Up-Regulation | 2001 |
Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma.
Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA Primers; DNA, Neoplasm; fas Receptor; Flow Cytometry; Gene Expression; Humans; Immunoenzyme Techniques; In Vitro Techniques; Male; Middle Aged; NF-kappa B; Oncogene Proteins v-rel; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiolester Hydrolases; Urinary Bladder Neoplasms | 2001 |
Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines.
Topics: Adenocarcinoma; Antigens, CD; Azacitidine; Base Sequence; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Kangai-1 Protein; Male; Membrane Glycoproteins; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Proto-Oncogene Proteins; Sulfites; Tumor Cells, Cultured | 2001 |
CpG hypermethylation of the promoter region inactivates the estrogen receptor-beta gene in patients with prostate carcinoma.
Topics: Azacitidine; Decitabine; DNA Methylation; DNA Modification Methylases; Estrogen Receptor beta; Gene Expression Regulation; Humans; Male; Neoplasms, Hormone-Dependent; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2001 |
DNA methylation regulates the expression of Y chromosome specific genes in prostate cancer.
Topics: Azacitidine; DNA Methylation; Gene Expression; Humans; Male; Polymerase Chain Reaction; Prostatic Neoplasms; RNA; Tumor Cells, Cultured; Y Chromosome | 2002 |
Metastatic phenotype of human prostate tumor cells in athymic nude mice: alteration by exposure to ethyl methanesulfonate and "reversion" by 5-azacytidine.
Topics: Animals; Azacitidine; Cell Line; Ethyl Methanesulfonate; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Phenotype; Prostatic Neoplasms | 1986 |
Clonal variation in the impact of ethyl methanesulfonate and 5-azacytidine on the metastatic phenotype of human prostatic tumor cells in athymic nude mice.
Topics: Animals; Azacitidine; Clone Cells; Ethyl Methanesulfonate; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Prostatic Neoplasms; Tumor Cells, Cultured | 1988 |