azacitidine has been researched along with Pregnancy in 122 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 29 (23.77) | 18.7374 |
1990's | 20 (16.39) | 18.2507 |
2000's | 25 (20.49) | 29.6817 |
2010's | 43 (35.25) | 24.3611 |
2020's | 5 (4.10) | 2.80 |
Authors | Studies |
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Bulić-Jakuš, F; Himelreich-Perić, M; Ježek, D; Jurić-Lekić, G; Katušić-Bojanac, A; Krasić, J; Majić, Ž; Marić, A; Šerman, L; Sinčić, N; Sobočan, N | 1 |
Alajaji, NM; Alhazzani, SA; Alnajjar, FH; Alrajhi, AM; Alshehry, NF; Tailor, IK | 1 |
Ding, HK; DU, L; Feng, XQ; Gao, Y; Huang, JX; Lan, FF; Li, TL; Liu, SS; Mao, CX; Meng, FJ; Nie, SM; Qin, DQ; Wang, JC; Yan, XS; Yang, Q; Yao, CZ; Yuan, TL | 1 |
Choi, EJ; Eun, K; Hong, N; Hwang, SU; Hwang, WS; Hyun, SH; Jeong, YIK; Jeong, YW; Kim, H; Olsson, PO; Park, MG | 1 |
Chen, PM; Hsu, PJ; Hwa, HL; Jiang, SS; Liu, KJ; Sytwu, HK; Wang, LT; Yen, BL; Yen, ML | 1 |
Arcuri, S; Brevini, TAL; Gandolfi, F; Somigliana, E | 1 |
Aleström, P; Kamstra, JH; Legler, J; Sales, LB | 1 |
Bai, M; Jiang, H; Jiang, T; Ma, Z; Sun, D; Weng, Y; Yang, X; Zheng, C | 1 |
Chen, M; Xiong, F; Zhang, L | 1 |
Bao, C; Ding, F; Ma, N; Mei, J; Zhang, J; Zhong, H | 1 |
Guizzetti, M; Kusumo, H; Pandey, SC; Sakharkar, AJ; Zhang, X | 1 |
Bulic-Jakus, F; Himelreich, M; Juric-Lekic, G; Katusic Bojanac, A; Marn, N; Muzic, V; Serman, L; Sincic, N; Tupek, K; Vlahovic, M | 1 |
He, L; Mor, E; Shomron, N; Torchinsky, A | 1 |
Beristain, AG; Hogg, K; Robinson, WP | 1 |
Bulic-Jakus, F; Curkovic-Perica, M; Fabijanovic, D; Jezic, M; Juric-Lekic, G; Katusic, A; Serman, A; Serman, L; Sincic, N; Vlahovic, M | 1 |
Hou, Z; Li, L; Lu, L; Miao, Z; Ren, M; Wang, X; Yang, Y; Yao, Y; Yu, L; Zhang, B; Zhao, D | 1 |
Agrawal, R; Gomez-Pinilla, F; Tyagi, E; Ying, Z; Zhuang, Y | 1 |
Chen, G; Ren, Y; Ruan, Z; Wang, R; Yin, Y; Yue, A; Zhu, L | 1 |
Anthony, S; Corre, A; Gong, M; Liu, J; Rehan, VK; Sakurai, R | 1 |
Chen, M; Dasgupta, C; Hu, XQ; Xiao, D; Yang, S; Zhang, L | 1 |
Gu, W; Li, H; Li, X; Liu, H; Peng, T; Tang, Y | 1 |
Mitchell, MD; Ponnampalam, AP; Vincent, ZL | 1 |
Lin, T; Lv, J; Ma, Q; Martinez, SR; MataGreenwood, E; Song, M; Xiao, D; Xiong, F; Xu, Z; Zhang, L | 1 |
Alves, CP; de Araújo, LF; de Molfetta, GA; Dinarte-Santos, AR; Lima e Bueno, Rde B; Lorenzi, JC; Muys, BR; Ramão, A; Silva, WA; Vidal, DO; Zanette, DL | 1 |
Barash, I; Kfir, S; Kisliouk, T; Rauner, G; Reichenstein, M | 1 |
Dasgupta, C; Gay, MS; Kanna, A; Li, Y; Zhang, L | 1 |
Bhasin, M; Burke, SD; Cavalli, RC; Cerdeira, AS; Karumanchi, SA; Kopcow, HD; Korkes, HA; Pernicone, E; Rajakumar, A; Roberts, DJ; Thadhani, RI | 1 |
Alvares, C; Chakraborty, M; Conner, C; Gosrani, D; Mahdi, AJ; Rayment, R; Rees, A; Wilson, K | 1 |
Brock, G; Greene, RM; Mukhopadhyay, P; Pisano, MM; Rezzoug, F; Seelan, RS; Smolenkova, IA; Warner, DR | 1 |
Greene, RM; Mukhopadhyay, P; Pisano, MM; Seelan, RS; Smolenkova, IA; Warner, DR | 1 |
Chen, M; Dasgupta, C; Hu, XQ; Huang, X; Xiao, D; Yang, S; Zhang, L | 1 |
Marutha Ravindran, CR; Ticku, MK | 2 |
Bailey, N; Boon, K; Brass, DM; Garantziotis, S; Hollingsworth, JW; Li, Z; Maruoka, S; Potts, EN; Schwartz, DA; Tomfohr, J; Whitehead, G | 1 |
Meyer, K; Zhang, H; Zhang, L | 1 |
Chu, Y; Dou, Z; Shen, W; Zhang, Y | 1 |
Alonso-Vega, C; Berthe, A; Braud, VM; Carlier, Y; Hermann, E; Parrado, R; Torrico, F; Truyens, C | 1 |
Barrera-Saldaña, HA; Castrillo-Diez, JL; de Jesús Romero-Prado, MM | 1 |
Chen, M; Patterson, AJ; Xiao, D; Xue, Q; Zhang, L | 1 |
Fabijanovic, D; Serman, A; Serman, L | 1 |
An, ZX; Hua, S; Liu, J; Quan, FS; Wang, LJ; Wang, YS; Xiong, XR; Zhang, Y | 1 |
Chen, Y; Love, A; Zhou, FC | 1 |
Kobyliansky, E; Mizrahi, L; Savion, S; Shahar, R; Toder, V; Torchinsky, A | 1 |
Butorina, NN; Kozhevnikova, MN; Paiushina, OV; Sheveleva, ON; Starostin, VI | 1 |
Bhatti, G; Chaiworapongsa, T; Elsey, A; Hassan, SS; Kang, GH; Kim, CJ; Kim, JS; Kim, SY; Lee, J; Romero, R; Tarca, AL; Than, NG | 1 |
Chiaratti, MR; de Araújo, RR; De Bem, TH; Meirelles, FV; Oliveira, Lde J; Perecin, F; Sangalli, JR; Smith, LC; Valim Pimentel, JR | 1 |
Kawamichi, Y; Saito, K; Umezawa, A | 1 |
Cappello, RE; Estrada-Gutierrez, G; Mousa, AA; Romero, R; Shukla, J; Strauss, JF; Walsh, SW | 1 |
Chen, XM; Ding, YB; Guo, LR; He, JL; Liu, XQ; Long, CL; Wang, YX; Xia, YY | 1 |
Chung, D; Das, SK; Gao, F; Hemingway, J; Ma, X; Ostmann, AB; Rusie, A | 1 |
Ding, X; Fan, M; Huang, X; Liu, S; Liu, ZH; Wang, F; Wu, K; Wu, LY; Wu, Y; Xiong, L; Zhao, T; Zhao, Y; Zhu, LL | 1 |
Lumbers, ER; Pringle, KG; Wang, Y | 1 |
Chen, Y; Leach, R; Wang, K | 1 |
Doi, K; Katayama, K; Nakayama, H; Ueno, M; Yasoshima, A | 1 |
Bestor, TH; Lynch, CA; Tycko, B; Walsh, CP | 1 |
Hatta, T; Matsumoto, A; Moriyama, K; Otani, H | 2 |
Anderson, LM; Branch, S; Cisneros, FJ; Travlos, G; Wilson, R | 1 |
Cheng, F; Yang, H; Yu, Z; Zhong, Z; Zou, P | 1 |
Hoffman, AR; Hu, JF; Li, T; Ulaner, GA; Vu, TH; Yang, Y | 1 |
Branch, S; Cisneros, FJ | 1 |
Mitchell, MD; Sato, TA | 1 |
Doi, K; Katayama, K; Nakayama, H; Ueno, M; Yamauchi, H | 2 |
Billstrand, C; Kuldanek, S; Ober, C; Tan, Z | 1 |
Gaensler, K; Ginder, GD; Lloyd, J; Rupon, JW; Wang, SZ | 1 |
Balasubramanian, S; Choe, SY; Hong, Y; Jin, HF; Kim, JG; Mohana Kumar, B; Rho, GJ; Song, HJ | 1 |
Coffin, J; Dokras, A; Field, L; Frakes, A; Lee, H; Madan, A; Nelson, T; Ryu, GY; Yoon, JG | 1 |
Doi, K; Katayama, K; Nakayama, H; Ueno, M; Yamauchi, H; Yasoshima, A | 1 |
Chan, KY; Cheung, AN; Li, AS; Ngan, HY; Siu, MK; Wong, ES; Wong, KY; Zhang, HJ | 1 |
Fleshman, JW; Jones, EG; Valentino, KL | 1 |
Bolander, FF | 1 |
Schmahl, W | 2 |
Isham, KR; Kenney, FT; Lee, KL; Perry, ST; Rothrock, R | 1 |
Cypress, GC; Nalbandian, RM | 1 |
DeSimone, J; Espinueva, Z; Hall, L; Huynh, V; Schroeder, WA; Shelton, JB; Shelton, JR; Zwiers, D | 1 |
Rodier, PM | 3 |
Alavi, JB | 1 |
Kriegel, H; Schmahl, W; Török, P | 1 |
Brunner, RL; Butcher, RE; Vorhees, CV | 1 |
Baik, MG; Choi, YJ; Roh, SG; Woo, JH | 1 |
Jaenisch, R; Jüttermann, R; Li, E | 1 |
Cummings, AM | 1 |
Dixon-McCarthy, B; Gill, TJ; Kunz, HW; Yuan, XJ | 1 |
Alles, AJ; Chernoff, N; Elstein, KH; Francis, BM; Massaro, EJ; Rogers, JM; Rosen, MB; Sulik, KK; Zucker, RM | 1 |
Leone, VG; Londei, T; Mistò, R; Vismara, C | 1 |
Goto, N; Hossain, MM; Nakayama, H | 1 |
Branch, S; Brownie, CF; Chernoff, N; Francis, BM | 1 |
Doerksen, T; Trasler, JM | 1 |
Arvola, M; Brunsberg, U; Gustafsson, E; Mattsson, A; Mattsson, R | 1 |
Branch, S; Brownie, CF; Chernoff, N; Francis, BM; Held, GA; Rosen, MB | 1 |
Atalay, A; Başimoglu-Koca, Y; Bulut, HE; Korkmaz, M; Ozdemir, O | 1 |
Branch, S; Brownie, C; Chernoff, N; Francis, BM | 1 |
Bulić-Jakus, F; Fucić, A; Jurić-Lekić, G; Marić, S; Serman, D; Vlahović, M | 1 |
Aifantis, I; Athanassakis, I; Baritakis, S; Farmakiotis, V; Koumantakis, E; Vassiliadis, S | 1 |
Benoit, G; Doerksen, T; Trasler, JM | 1 |
Hill, J; Jones, KL; Lui, L; Shin, TY; Westhusin, M | 1 |
Cihák, A; Seifertová, M; Veselý, J | 2 |
Bear, RA; Garvey, MB; Ho, M | 1 |
Reynolds, SS; Rodier, PM | 1 |
Murakami, U; Takeuchi, IK | 1 |
Constantinides, PG; Jones, PA; Taylor, SM | 1 |
Reynolds, SS; Roberts, WN; Rodier, PM | 1 |
Ranney, HM | 1 |
Chernoff, N; Francis, BM; House, HS; Rosen, MB | 1 |
Matsuda, M | 1 |
Ihara, T; Kurishita, A | 2 |
Athanassakis-Vassiliadis, I; Galanopoulos, VK; Grigoriou, M; Papamatheakis, J | 1 |
Drahovsky, D; Jovin, TM; Kalisch, BW; McIntosh, LP; Pfeifer, GP; Sprinzl, M; van de Sande, JH; Zielinski, WS | 1 |
Benvenisty, N; Mencher, D; Razin, A; Reshef, L; Szyf, M | 1 |
Darmon, M; Duprey, P; Sémat, A; Vasseur, M | 1 |
Schmahl, WG; Weber, LW | 1 |
Benvenisty, N; Mencher, D; Meyuhas, O; Razin, A; Reshef, L | 1 |
Anderson, WF; Baur, A; Berg, P; Bernstein, S; DiPietro, J; Humphries, RK; Nienhuis, AW | 1 |
Cihák, A; Seifertová, M; Sorm, F; Vesselý, J | 1 |
4 review(s) available for azacitidine and Pregnancy
Article | Year |
---|---|
[Cell fusion as a key mechanism for cell-based therapy towards Duchenne muscular dystrophy].
Topics: Animals; Azacitidine; Cell Differentiation; Cell Fusion; Cell Transplantation; Cell- and Tissue-Based Therapy; Disease Models, Animal; Dystrophin; Endometrium; Female; Humans; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Placenta; Pregnancy; Regenerative Medicine | 2012 |
Sickle cell anemia. Pathophysiology and treatment.
Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Azepines; Blood Transfusion; Cerebrovascular Disorders; Child; Child, Preschool; Female; Folic Acid; Humans; Male; Phenothiazines; Pneumococcal Infections; Pregnancy; Pregnancy Complications, Hematologic; Priapism; Urea; Vaccination | 1984 |
The spectrum of sickle cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Azacitidine; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 16; Female; Fluid Therapy; Genotype; Globins; Hemoglobin, Sickle; Humans; Hydroxyurea; Male; Oxygen Inhalation Therapy; Polymorphism, Genetic; Pregnancy | 1992 |
Azacitidine.
Topics: Animals; Azacitidine; Carcinogens; Female; Humans; Male; Molecular Structure; Pregnancy | 1990 |
2 trial(s) available for azacitidine and Pregnancy
Article | Year |
---|---|
Methylome of fetal and maternal monocytes and macrophages at the feto-maternal interface.
Topics: Adult; Antimetabolites, Antineoplastic; Azacitidine; Carrier Proteins; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Fetus; Gene Expression Regulation; Humans; Macrophages; Monocytes; Phosphoproteins; Placenta; Pregnancy; Pregnancy Proteins; RNA, Messenger | 2012 |
Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of cloned cattle.
Topics: Acetylation; Animals; Azacitidine; Cattle; Cell Nucleus; Cells, Cultured; Chromatin Assembly and Disassembly; Cloning, Organism; Decitabine; Embryonic Development; Female; Histone Deacetylase Inhibitors; Histones; Hydralazine; Hydroxamic Acids; Nuclear Transfer Techniques; Pregnancy; Term Birth; Up-Regulation; Valproic Acid; Zygote | 2012 |
116 other study(ies) available for azacitidine and Pregnancy
Article | Year |
---|---|
Extended Prophylactic Effect of N-tert-Butyl-α-phenylnitron against Oxidative/Nitrosative Damage Caused by the DNA-Hypomethylating Drug 5-Azacytidine in the Rat Placenta.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azacitidine; Biomarkers; Cell Proliferation; Cyclic N-Oxides; DNA Methylation; Female; Nitrosation; Organ Size; Oxidative Stress; Placenta; Pregnancy; Proliferating Cell Nuclear Antigen; Rats, Inbred F344; Tyrosine | 2022 |
The use of 5-azacytidine in pregnant patient with Acute Myeloid Leukemia (AML): a case report.
Topics: Adult; Antimetabolites, Antineoplastic; Azacitidine; Cesarean Section; Female; Humans; Induction Chemotherapy; Infant, Newborn; Leukemia, Myeloid, Acute; Live Birth; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Trimester, Third | 2019 |
Topics: Azacitidine; beta-Globins; beta-Thalassemia; DNA Mutational Analysis; Female; Heterozygote; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Phenotype; Pregnancy; Retrospective Studies; Risk Factors; Silent Mutation; Treatment Outcome | 2020 |
Transcriptional activities of human elongation factor-1α and cytomegalovirus promoter in transgenic dogs generated by somatic cell nuclear transfer.
Topics: Animals; Animals, Genetically Modified; Azacitidine; Cells, Cultured; Cloning, Organism; Cytomegalovirus; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dogs; Embryo Transfer; Female; Fibroblasts; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Nuclear Transfer Techniques; Peptide Elongation Factor 1; Pregnancy; Promoter Regions, Genetic; Transcriptional Activation; Transfection; Transgenes | 2020 |
HLA-G Expression in Human Mesenchymal Stem Cells (MSCs) Is Related to Unique Methylation Pattern in the Proximal Promoter as well as Gene Body DNA.
Topics: Azacitidine; Bone Marrow Cells; Cell Line, Tumor; CpG Islands; Demethylation; DNA; DNA Methylation; Embryonic Stem Cells; Female; Fibroblasts; Gene Expression Regulation; HLA-G Antigens; Humans; Interferon-gamma; Mesenchymal Stem Cells; Placenta; Pregnancy; Promoter Regions, Genetic; Protein Isoforms; Tandem Mass Spectrometry | 2020 |
A Two-Step Protocol to Erase Human Skin Fibroblasts and Convert Them into Trophoblast-like Cells.
Topics: Activins; Animals; Azacitidine; Bone Morphogenetic Protein 4; Cell Culture Techniques; Cell Differentiation; Embryo Implantation; Embryo, Mammalian; Embryonic Stem Cells; Female; Fibroblasts; Humans; MAP Kinase Signaling System; Mice; Nodal Protein; Placenta; Pregnancy; Signal Transduction; Skin; Trophoblasts | 2021 |
Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish.
Topics: Animals; Azacitidine; Brain; Diethylhexyl Phthalate; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Female; Gene Expression Regulation, Developmental; Larva; Liver; Male; Mutagenesis; Pregnancy; Sequence Analysis, DNA; Spermatozoa; Zebrafish; Zebrafish Proteins | 2017 |
Multiple drug transporters mediate the placental transport of sulpiride.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Azacitidine; Carrier Proteins; Cell Line; Decitabine; Female; Humans; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Placenta; Pregnancy; Solute Carrier Family 22 Member 5; Sulpiride; Symporters; Trophoblasts | 2017 |
Promoter methylation of Egr-1 site contributes to fetal hypoxia-mediated PKCε gene repression in the developing heart.
Topics: Animals; Animals, Newborn; Antimetabolites; Azacitidine; Binding Sites; Blotting, Western; Chromatin Immunoprecipitation; DNA Methylation; Early Growth Response Protein 1; Electrophoretic Mobility Shift Assay; Epigenesis, Genetic; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fetal Hypoxia; Heart; Male; Myocardium; Pregnancy; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Sex Characteristics | 2013 |
Myocardial structural protein expression in umbilical cord blood mesenchymal stem cells after myogenic induction.
Topics: Actins; Animals; Antigens, CD; Azacitidine; Cell Differentiation; Desmin; Dogs; Female; Fetal Blood; Fetus; Gene Expression Regulation, Developmental; Histocompatibility Antigens Class II; Mesenchymal Stem Cells; Myocytes, Cardiac; Pregnancy; Signal Transduction; Transcription Factors; Troponin I | 2013 |
Regulation of DNA methylation by ethanol induces tissue plasminogen activator expression in astrocytes.
Topics: Animals; Antimetabolites, Antineoplastic; Astrocytes; Azacitidine; Blotting, Western; Cells, Cultured; Central Nervous System Depressants; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Enzyme-Linked Immunosorbent Assay; Ethanol; Female; Gene Expression Regulation; Pregnancy; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tissue Plasminogen Activator | 2014 |
Epigenetic drug 5-azacytidine impairs proliferation of rat limb buds in an organotypic model-system in vitro.
Topics: Animals; Azacitidine; Cell Differentiation; Cell Proliferation; Epigenomics; Female; Humans; Limb Buds; Organ Culture Techniques; Pregnancy; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Teratogens | 2013 |
MicroRNA-34a is dispensable for p53 function as teratogenesis inducer.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; Decitabine; Dose-Response Relationship, Drug; Drug Resistance; Female; Fetal Development; Gene Expression Profiling; Gene Expression Regulation, Developmental; Heterozygote; Limb Buds; Limb Deformities, Congenital; Male; Mice, Inbred ICR; Mice, Knockout; MicroRNAs; Pregnancy; Rats, Sprague-Dawley; Teratogens; Tumor Suppressor Protein p53; Up-Regulation | 2014 |
Activation of endocrine-related gene expression in placental choriocarcinoma cell lines following DNA methylation knock-down.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aromatase; Azacitidine; Cell Line, Tumor; Choriocarcinoma; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Leptin; Placenta; Pregnancy; Promoter Regions, Genetic; Receptors, Glucocorticoid; TEA Domain Transcription Factors; Transcription Factors; Uterine Neoplasms | 2014 |
Impact of 5-azacytidine on rat decidual cell proliferation.
Topics: Animals; Azacitidine; Biomarkers; Cell Proliferation; Decidua; DNA Methylation; Enzyme Inhibitors; Female; Models, Animal; Pregnancy; Pregnancy, Animal; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344 | 2014 |
Methylation pattern of H19 exon 1 is closely related to preeclampsia and trophoblast abnormalities.
Topics: Adult; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Placenta; Pre-Eclampsia; Pregnancy; RNA, Long Noncoding; RNA, Messenger; Trophoblasts; Young Adult | 2014 |
Interactive actions of Bdnf methylation and cell metabolism for building neural resilience under the influence of diet.
Topics: Animals; Anxiety; Azacitidine; Brain; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Decitabine; Diet, Fat-Restricted; Disease Models, Animal; Enzyme Inhibitors; Fatty Acids, Omega-3; Female; Male; Maze Learning; Methylation; Mice; Neuroblastoma; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Transcription Factors | 2015 |
Potential of 5-azacytidine induction decidual stromal cells from maternal human term placenta towards cardiomyocyte-like cells in serum-free medium.
Topics: Azacitidine; Batch Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Culture Media, Serum-Free; Decidua; Enzyme Inhibitors; Feasibility Studies; Female; Humans; Myocytes, Cardiac; Pregnancy; Stem Cells; Tissue Engineering | 2015 |
Perinatal nicotine exposure suppresses PPARγ epigenetically in lung alveolar interstitial fibroblasts.
Topics: Animals; Azacitidine; Base Sequence; Cells, Cultured; Decitabine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Fibroblasts; Fibronectins; Humans; Lung; Methyl-CpG-Binding Protein 2; Molecular Sequence Data; Nicotine; PPAR gamma; Pregnancy; Promoter Regions, Genetic; Pulmonary Alveoli; Rats; RNA, Messenger; Smoking; Up-Regulation | 2015 |
Hypoxia Represses ER-α Expression and Inhibits Estrogen-Induced Regulation of Ca2+-Activated K+ Channel Activity and Myogenic Tone in Ovine Uterine Arteries: Causal Role of DNA Methylation.
Topics: Acetylcysteine; Animals; Azacitidine; Decitabine; DNA Methylation; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation; Hypoxia; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Pregnancy; Pregnancy Complications; Progesterone; Promoter Regions, Genetic; Reactive Oxygen Species; Sheep; Uterine Artery; Vascular Resistance | 2015 |
Hypermethylation of the HLA-G promoter is associated with preeclampsia.
Topics: Adult; Azacitidine; Case-Control Studies; Cell Line; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Genetic Association Studies; Genetic Predisposition to Disease; HLA-G Antigens; Humans; Phenotype; Placenta; Pre-Eclampsia; Pregnancy; Promoter Regions, Genetic; RNA Interference; Transfection; Trophoblasts | 2015 |
Regulation of TIMP-1 in Human Placenta and Fetal Membranes by lipopolysaccharide and demethylating agent 5-aza-2'-deoxycytidine.
Topics: Amnion; Azacitidine; Chorion; Chorionic Villi; Chromatin; Decidua; Decitabine; DNA Methylation; Epigenesis, Genetic; Extraembryonic Membranes; Female; Fetal Membranes, Premature Rupture; Gene Expression Regulation; Humans; Lipopolysaccharides; Placenta; Pregnancy; Real-Time Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinase-1; Transcription, Genetic | 2015 |
Antenatal hypoxia induces epigenetic repression of glucocorticoid receptor and promotes ischemic-sensitive phenotype in the developing heart.
Topics: Animals; Animals, Newborn; Azacitidine; Binding Sites; Decitabine; DNA Methylation; Epigenesis, Genetic; Exons; Female; Hypoxia; Male; Maternal Exposure; Myocardial Reperfusion Injury; Oxygen; Phenotype; Pregnancy; Promoter Regions, Genetic; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Response Elements; Sp1 Transcription Factor | 2016 |
Placenta-Enriched LincRNAs MIR503HG and LINC00629 Decrease Migration and Invasion Potential of JEG-3 Cell Line.
Topics: Azacitidine; Cell Line, Tumor; Cell Movement; Cell Nucleus; Conserved Sequence; DNA Methylation; Evolution, Molecular; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasm Invasiveness; Nucleic Acid Conformation; Placenta; Pregnancy; Protein Isoforms; Reproduction; RNA, Long Noncoding | 2016 |
Luminal STAT5 mediates H2AX promoter activity in distinct population of basal mammary epithelial cells.
Topics: Animals; Azacitidine; Cell Line; Cells, Cultured; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Female; Gene Expression Regulation; Histones; Mammary Glands, Animal; Mice, Knockout; Mice, Transgenic; Pregnancy; Promoter Regions, Genetic; STAT5 Transcription Factor | 2016 |
Dexamethasone Induces Cardiomyocyte Terminal Differentiation via Epigenetic Repression of Cyclin D2 Gene.
Topics: Animals; Animals, Newborn; Azacitidine; Cell Differentiation; Cell Proliferation; Cyclin D2; Decitabine; Dexamethasone; DNA Methylation; Down-Regulation; Epigenetic Repression; Female; Myocytes, Cardiac; Pregnancy; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley | 2016 |
Induced Human Decidual NK-Like Cells Improve Utero-Placental Perfusion in Mice.
Topics: Animals; Azacitidine; CD56 Antigen; Cell Hypoxia; Decidua; Decitabine; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Immunocompromised Host; Killer Cells, Natural; Mice; Placenta; Pregnancy; Transforming Growth Factor beta | 2016 |
Successful molecular targeted treatment of AML in pregnancy with Azacitidine and Sorafenib with no adverse fetal outcomes.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Female; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Pregnancy; Pregnancy Complications, Neoplastic; Sorafenib; Treatment Outcome | 2018 |
Determinants of orofacial clefting I: Effects of 5-Aza-2'-deoxycytidine on cellular processes and gene expression during development of the first branchial arch.
Topics: Animals; Apoptosis; Azacitidine; Branchial Region; Cell Proliferation; Cleft Palate; Decitabine; DNA Methylation; Embryonic Development; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gestational Age; Mice, Inbred ICR; Pregnancy | 2017 |
Determinants of orofacial clefting II: Effects of 5-Aza-2'-deoxycytidine on gene methylation during development of the first branchial arch.
Topics: Animals; Azacitidine; Branchial Region; Cleft Palate; Decitabine; DNA Methylation; Embryonic Development; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gestational Age; Mice, Inbred ICR; Pregnancy | 2017 |
Chronic hypoxia upregulates DNA methyltransferase and represses large conductance Ca2+-activated K+ channel function in ovine uterine arteries.
Topics: Altitude; Animals; Azacitidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Female; Gene Expression Regulation, Enzymologic; Hypoxia; Potassium Channels, Calcium-Activated; Pregnancy; Sheep; Uterine Artery; Vasodilation | 2017 |
Effect of 5-azacytidine on the methylation aspects of NMDA receptor NR2B gene in the cultured cortical neurons of mice.
Topics: Animals; Azacitidine; Blotting, Southern; Cells, Cultured; Cerebral Cortex; DNA Methylation; Female; Mice; Mice, Inbred C57BL; Neurons; Polymerase Chain Reaction; Pregnancy; Receptors, N-Methyl-D-Aspartate | 2009 |
In utero supplementation with methyl donors enhances allergic airway disease in mice.
Topics: Animals; Asthma; Azacitidine; Cytokines; Dietary Supplements; Disease Models, Animal; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Reproducibility of Results; Spleen | 2008 |
Direct effect of cocaine on epigenetic regulation of PKCepsilon gene repression in the fetal rat heart.
Topics: Animals; Azacitidine; Base Sequence; Binding Sites; Cocaine; DNA Methylation; Enzyme Repression; Epigenesis, Genetic; Female; Fetus; Molecular Sequence Data; Mutation; Myocardium; Pregnancy; Procainamide; Promoter Regions, Genetic; Protein Binding; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sp1 Transcription Factor | 2009 |
Effect of 5-azacytidine induction duration on differentiation of human first-trimester fetal mesenchymal stem cells towards cardiomyocyte-like cells.
Topics: Aborted Fetus; Azacitidine; Biomarkers; Cell Differentiation; Cell Proliferation; Cell Shape; Cells, Cultured; Female; Fetal Stem Cells; Gene Expression Regulation, Developmental; Humans; Mesenchymal Stem Cells; Myocytes, Cardiac; Pregnancy; Pregnancy Trimester, First; RNA, Messenger; Time Factors | 2009 |
Killer cell immunoglobulin-like receptor expression induction on neonatal CD8(+) T cells in vitro and following congenital infection with Trypanosoma cruzi.
Topics: Antibodies, Monoclonal; Antigens, CD; Azacitidine; CD3 Complex; CD8-Positive T-Lymphocytes; Chagas Disease; Decitabine; DNA Modification Methylases; Enzyme Inhibitors; Female; Fetal Blood; Humans; Immunophenotyping; Infant, Newborn; Infant, Newborn, Diseases; Interleukin-2; NK Cell Lectin-Like Receptor Subfamily C; Pregnancy; Receptors, Antigen, T-Cell, alpha-beta; Receptors, KIR; Receptors, KIR2DL1; Receptors, KIR2DL2; Receptors, KIR2DL3; Receptors, KIR3DL1; T-Lymphocyte Subsets; Trypanosoma cruzi | 2010 |
hGH-V gene expression and promoter activity under glucose and 5-azacytidine (5azaC) effects.
Topics: Azacitidine; Base Sequence; Cell Line; Cell Line, Tumor; Chromosomes, Artificial, P1 Bacteriophage; DNA Methylation; Electrophoretic Mobility Shift Assay; Female; Gene Expression Regulation; Genetic Loci; Genome, Human; Glucose; Growth Hormone; Humans; Molecular Sequence Data; Placenta; Placental Hormones; Placental Lactogen; Pregnancy; Promoter Regions, Genetic; Transcription Factors; Transcription, Genetic; Transfection | 2010 |
Chronic prenatal hypoxia induces epigenetic programming of PKC{epsilon} gene repression in rat hearts.
Topics: Animals; Azacitidine; Blotting, Western; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Female; Fetal Heart; Fetal Hypoxia; Gene Expression Regulation, Enzymologic; Male; Methylation; Pregnancy; Promoter Regions, Genetic; Protein Kinase C-epsilon; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sp1 Transcription Factor | 2010 |
An in vivo rat model to study epigenetic control of cell invasion.
Topics: Animals; Azacitidine; Cell Differentiation; Cell Movement; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation; Gene Silencing; Models, Animal; Placenta; Placentation; Pregnancy; Rats | 2011 |
Production of cloned calves by combination treatment of both donor cells and early cloned embryos with 5-aza-2/-deoxycytidine and trichostatin A.
Topics: Animals; Azacitidine; Blastocyst; Cattle; Cloning, Organism; Decitabine; Embryo Transfer; Embryonic Development; Female; Hydroxamic Acids; Nuclear Transfer Techniques; Pregnancy; Pregnancy Outcome | 2011 |
Cellular DNA methylation program during neurulation and its alteration by alcohol exposure.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cells, Cultured; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neural Tube; Neurulation; Pregnancy; Repressor Proteins; Transcription Factors | 2011 |
Bone loss in adult offspring induced by low-dose exposure to teratogens.
Topics: Acid Phosphatase; Aging; Animals; Apoptosis; Azacitidine; Bone Resorption; Embryo, Mammalian; Female; Femur; Gene Expression Profiling; Gene Expression Regulation, Developmental; Hindlimb; Isoenzymes; Limb Buds; Mice; Mice, Inbred ICR; MicroRNAs; Osteoblasts; Osteogenesis; Osteoprotegerin; Pregnancy; Prenatal Exposure Delayed Effects; RANK Ligand; Reproduction; Tartrate-Resistant Acid Phosphatase; Teratogens; X-Ray Microtomography | 2012 |
[Spontaneous and induced myogenesis in cell culture from rat fetal liver].
Topics: Animals; Azacitidine; Cell Differentiation; Desmin; Female; Fetal Development; Fetus; Gene Expression; Immunohistochemistry; Liver; Mesenchymal Stem Cells; Muscle Development; Muscle Fibers, Skeletal; Muscle, Skeletal; MyoD Protein; Myogenin; Pregnancy; Primary Cell Culture; Protein Precursors; Rats; Rats, Wistar; Time Factors | 2011 |
Preeclampsia is associated with alterations in DNA methylation of genes involved in collagen metabolism.
Topics: Adult; Azacitidine; Blood Vessels; Cells, Cultured; Collagen; Collagen Type I; DNA Methylation; Female; Humans; Immunohistochemistry; Matrix Metalloproteinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pre-Eclampsia; Pregnancy; Promoter Regions, Genetic; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases | 2012 |
5-aza-2'-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes.
Topics: Animals; Azacitidine; Blotting, Western; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Embryo Implantation; Endometrium; Estrogen Receptor alpha; Female; Homeobox A10 Proteins; Homeodomain Proteins; Immunohistochemistry; Male; Mice; Pregnancy; Receptors, Progesterone | 2012 |
Epigenetic changes through DNA methylation contribute to uterine stromal cell decidualization.
Topics: Animals; Azacitidine; CpG Islands; Decidua; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Female; Mice; Pregnancy; Pregnancy, Animal; Promoter Regions, Genetic; Stromal Cells; Uterus | 2012 |
DNA demethylation regulates the expression of miR-210 in neural progenitor cells subjected to hypoxia.
Topics: Animals; Azacitidine; Blotting, Western; Cell Hypoxia; Cells, Cultured; Decitabine; DNA Methylation; DNA Modification Methylases; Female; Hypoxia-Inducible Factor 1; MicroRNAs; Neural Stem Cells; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Wistar | 2012 |
The effects of cyclic AMP, sex steroids and global hypomethylation on the expression of genes controlling the activity of the renin-angiotensin system in placental cell lines.
Topics: Adult; Azacitidine; Cell Line, Tumor; Choriocarcinoma; Cyclic AMP; DNA Methylation; Drug Therapy, Combination; Estradiol; Female; Gene Expression Regulation, Developmental; Gene Silencing; Humans; Medroxyprogesterone Acetate; Pregnancy; Pregnancy Trimester, First; Renin-Angiotensin System; Trophoblasts | 2013 |
5-Aza-dC treatment induces mesenchymal-to-epithelial transition in 1st trimester trophoblast cell line HTR8/SVneo.
Topics: Azacitidine; Cadherins; Cell Line; Cytidine Triphosphate; DNA Methylation; DNA-Cytosine Methylases; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Humans; Keratin-7; Pregnancy; Pregnancy Trimester, First; Trophoblasts | 2013 |
5-Azacytidine (5AzC)-induced histopathological changes in the central nervous system of rat fetuses.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Brain; Embryonic and Fetal Development; Female; In Situ Nick-End Labeling; Mitosis; Pregnancy; Rats; Rats, Wistar | 2002 |
Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation.
Topics: Acetylation; Animals; Azacitidine; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cells, Cultured; DNA Methylation; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Insulin-Like Growth Factor II; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pregnancy; Rhabdomyosarcoma; RNA; RNA, Long Noncoding; RNA, Untranslated; Tissue Plasminogen Activator | 2002 |
Opposite effects of the maternal immune system activated by interleukin-1beta vs. PSK and OK432 on 5-azacytidine-induced birth defects.
Topics: Abnormalities, Multiple; Adjuvants, Immunologic; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Body Weight; Brain; Congenital Abnormalities; Female; Interleukin-1; Mice; Mice, Inbred ICR; Microscopy, Electron, Scanning; Phagocytes; Picibanil; Placenta; Pregnancy; Pregnancy, Animal; Proteoglycans; Teratogens; Time Factors | 2003 |
Susceptibility to postnatal growth retardation induced by 5-AZA-2'-deoxycytidine in utero: gender specificity and correlation with reduced insulin-like growth factor 1.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blood Glucose; Body Weight; Corticosterone; Decitabine; Depression, Chemical; Energy Metabolism; Female; Growth Disorders; Insulin-Like Growth Factor I; Mice; Pregnancy; Sex Characteristics | 2003 |
Induced differentiation of human cord blood mesenchymal stem/progenitor cells into cardiomyocyte-like cells in vitro.
Topics: Azacitidine; Cell Differentiation; Cells, Cultured; Culture Media, Conditioned; Female; Fetal Blood; Fluorescent Antibody Technique; Humans; Male; Mesenchymal Stem Cells; Myocytes, Cardiac; Pregnancy; Troponin T | 2003 |
The histone code regulating expression of the imprinted mouse Igf2r gene.
Topics: Acetylation; Alleles; Animals; Azacitidine; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation; Gene Silencing; Genomic Imprinting; Histones; Hydroxamic Acids; Male; Mice; Pregnancy; Receptor, IGF Type 2 | 2003 |
Changes in methylation pattern of NMDA receptor NR2B gene in cortical neurons after chronic ethanol treatment in mice.
Topics: Animals; Azacitidine; Blotting, Southern; Cells, Cultured; Central Nervous System Depressants; Cerebral Cortex; CpG Islands; DNA Methylation; Embryo, Mammalian; Enzyme Inhibitors; Ethanol; Female; Gene Expression; Mice; Mice, Inbred C57BL; Neurons; Polymerase Chain Reaction; Pregnancy; Receptors, N-Methyl-D-Aspartate; RNA | 2004 |
Transplacental exposure to the DNA demethylating agent, 5-AZA-CdR, affects the sexual behavior of CD-1 male mice.
Topics: Animals; Azacitidine; Decitabine; DNA Methylation; Female; Male; Maternal-Fetal Exchange; Mice; Pregnancy; Reaction Time; Sexual Behavior, Animal | 2004 |
Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS.
Topics: Acetylation; Azacitidine; Decidua; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Histones; Humans; Hydroxamic Acids; In Vitro Techniques; Interleukin-1; Interleukin-10; Pregnancy; Tumor Necrosis Factor-alpha | 2006 |
Cell cycle and cell death regulation of neural progenitor cells in the 5-azacytidine (5AzC)-treated developing fetal brain.
Topics: Animals; Azacitidine; Blotting, Western; Brain; Bromodeoxyuridine; Caspase 3; Caspases; Cell Cycle; Cell Death; DNA Fragmentation; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Histones; Microarray Analysis; Models, Biological; Neurons; Pregnancy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Time Factors; Tumor Suppressor Protein p53 | 2006 |
The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells.
Topics: Abortion, Spontaneous; Alleles; Azacitidine; Decitabine; DNA-Cytosine Methylases; Female; Haplotypes; Histocompatibility Antigens Class I; HLA Antigens; HLA-G Antigens; Humans; Interferon-beta; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide; Pregnancy; Promoter Regions, Genetic; Transcription, Genetic; Tumor Cells, Cultured | 2006 |
Methyl binding domain protein 2 mediates gamma-globin gene silencing in adult human betaYAC transgenic mice.
Topics: Animals; Azacitidine; Binding Sites; Chromosomes, Artificial, Yeast; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Erythroblasts; Female; Gene Expression Regulation, Developmental; Gene Silencing; Globins; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Pregnancy; Promoter Regions, Genetic | 2006 |
Cell cycle progression is required for nuclear migration of neural progenitor cells.
Topics: Animals; Apoptosis; Azacitidine; Bromodeoxyuridine; Cell Cycle; Cell Movement; Cell Nucleus; Cyclophosphamide; Enzyme Inhibitors; Female; Flow Cytometry; Immunohistochemistry; Immunosuppressive Agents; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Neurons; Pregnancy; Stem Cells; Telencephalon; Time Factors | 2006 |
DNA methylation levels in porcine fetal fibroblasts induced by an inhibitor of methylation, 5-azacytidine.
Topics: Animals; Apoptosis; Azacitidine; Cell Cycle; Cell Division; Cells, Cultured; DNA Methylation; Dose-Response Relationship, Drug; Female; Fibroblasts; Flow Cytometry; Microscopy, Confocal; Ploidies; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Time Factors | 2006 |
Epigenetic regulation of maspin expression in the human placenta.
Topics: Acetylation; Azacitidine; Cells, Cultured; Chromatin; CpG Islands; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genes, Tumor Suppressor; Gestational Age; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Placenta; Pregnancy; Promoter Regions, Genetic; Serpins | 2006 |
Repair process of fetal brain after 5-azacytidine-induced damage.
Topics: Animals; Apoptosis; Azacitidine; Brain; Brain Injuries; Calcium-Binding Proteins; Cell Cycle; Cytokines; Ectodysplasins; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Immunohistochemistry; In Situ Nick-End Labeling; Microarray Analysis; Microfilament Proteins; Microscopy, Electron, Transmission; Pregnancy; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Wound Healing | 2006 |
Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease.
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Exons; Female; Gene Expression Regulation, Neoplastic; Gestational Trophoblastic Disease; Humans; Hydroxamic Acids; Octamer Transcription Factor-3; Placenta; Pregnancy; Promoter Regions, Genetic; RNA, Messenger | 2008 |
5-azacytidine.
Topics: Animals; Azacitidine; Carcinogens; Chemical Phenomena; Chemistry; Female; Fetal Death; Humans; Lethal Dose 50; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mutagens; Pregnancy; Reproduction; Teratogens | 1981 |
Adjustment of connectivity in rat neocortex after prenatal destruction of precursor cells of layers II-IV.
Topics: Animals; Azacitidine; Azo Compounds; Cerebral Cortex; Efferent Pathways; Female; Methylazoxymethanol Acetate; Neurons; Pregnancy; Rats; Rats, Inbred Strains | 1981 |
The effect of 5-azacytidine on mammary gland differentiation in vitro.
Topics: Animals; Azacitidine; Cell Differentiation; Female; Lactation; Mammary Glands, Animal; Methylation; Mice; Mice, Inbred C3H; Pregnancy; Prolactin | 1983 |
Sequence-dependent toxicity and small bowel mucosal injury in neonatal mice treated with low doses of 5-azacytidine and X-irradiation at the late organogenesis stage.
Topics: Animals; Azacitidine; Female; Fetal Death; Intestinal Mucosa; Intestine, Small; Mice; Mice, Inbred Strains; Pregnancy | 1983 |
Activation of tyrosine aminotransferase expression in fetal liver by 5-azacytidine.
Topics: Animals; Azacitidine; Chemical Phenomena; Chemistry; Enzyme Activation; Female; Fetus; Liver; Pregnancy; Rats; Rats, Inbred Strains; Tyrosine Transaminase | 1983 |
Gene switching -- a new therapeutic epoch: discussion paper.
Topics: Anemia, Sickle Cell; Azacitidine; Female; Fetal Blood; Fetal Hemoglobin; Gene Expression Regulation; Genes; Hemoglobins; Humans; Operon; Pregnancy; Thalassemia | 1984 |
Speciation in the baboon and its relation to gamma-chain heterogeneity and to the response to induction of HbF by 5-azacytidine.
Topics: Amino Acid Sequence; Animals; Azacitidine; Biological Evolution; Female; Fetal Hemoglobin; Genes, Regulator; Globins; Male; Papio; Peptides; Pregnancy; Species Specificity; Stress, Physiological | 1984 |
Differential structural effects of three behavioral teratogens.
Topics: Animals; Azacitidine; Behavior; Brain; Cell Count; Cell Division; Female; Humans; Methylmercury Compounds; Nitrous Oxide; Pregnancy; Teratogens | 1983 |
Embryotoxicity of 5-azacytidine in mice. Phase- and dose-specificity studies.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Mice; Mice, Inbred Strains; Pregnancy | 1984 |
Developmental toxicity and psychotoxicity of potassium iodide in rats: a case for the inclusion of behaviour in toxicological assessment.
Topics: Administration, Oral; Animals; Azacitidine; Body Weight; Female; Fetal Death; Injections, Intraperitoneal; Litter Size; Male; Maternal-Fetal Exchange; Motor Activity; Organ Size; Potassium Iodide; Pregnancy; Rats; Rats, Inbred Strains; Reflex, Startle | 1984 |
Non-hormonal factors on differentiation of bovine mammary cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acids; Animals; Azacitidine; Cattle; Cell Differentiation; Cells, Cultured; Cyclic AMP; DNA; Enzyme Activation; Female; Mammary Glands, Animal; Methylation; Pregnancy; Protein Biosynthesis; Spermidine | 1994 |
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation.
Topics: Animals; Antineoplastic Agents; Azacitidine; Blotting, Southern; Cell Division; Cell Survival; Cells, Cultured; Crosses, Genetic; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Embryo, Mammalian; Female; Fibroblasts; Genotype; Heterozygote; Kinetics; Mice; Mutagens; Mutation; Pregnancy; Stem Cells | 1994 |
Effect of 5-azacytidine administration during very early pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Gestational Age; Pregnancy; Rats | 1994 |
Role of methylation in placental major histocompatibility complex antigen expression and fetal loss.
Topics: Animals; Azacitidine; DNA; Female; Fetal Death; Gene Expression; Genes, MHC Class I; Genes, MHC Class II; Genomic Imprinting; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Immunohistochemistry; Major Histocompatibility Complex; Methylation; Nucleic Acid Hybridization; Placenta; Pregnancy; Rats; Rats, Inbred WF; Specific Pathogen-Free Organisms | 1994 |
Cell death and cell cycle perturbation in the developmental toxicity of the demethylating agent, 5-aza-2'-deoxycytidine.
Topics: Animals; Azacitidine; Cell Cycle; Cell Death; Decitabine; DNA; Dose-Response Relationship, Drug; Female; Flow Cytometry; Limb Deformities, Congenital; Mice; Pregnancy; Teratogens | 1994 |
Congenital brain damage spares the basic patterns of parental behavior in affected mice.
Topics: Animals; Azacitidine; Body Weight; Brain; Brain Damage, Chronic; Cannibalism; Female; Male; Maternal Behavior; Mice; Motor Activity; Nesting Behavior; Paternal Behavior; Pregnancy; Reproduction | 1995 |
In vitro induction of apoptosis of developing brain cells by 5-azacytidine.
Topics: Animals; Apoptosis; Azacitidine; Biotin; Brain; Cells, Cultured; Deoxyuracil Nucleotides; DNA Damage; Female; Mice; Mice, Inbred ICR; Microscopy, Electron; Microscopy, Electron, Scanning; Neurons; Pregnancy; Staining and Labeling | 1996 |
Teratogenic effects of the demethylating agent 5-aza-2'-deoxycytidine in the Swiss Webster mouse.
Topics: Analysis of Variance; Animals; Azacitidine; Cleft Palate; Decitabine; DNA Damage; DNA Modification Methylases; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Gestational Age; Hindlimb; Injections, Intraperitoneal; Mice; Pregnancy; Ribs; Spine; Teratogens | 1996 |
Developmental exposure of male germ cells to 5-azacytidine results in abnormal preimplantation development in rats.
Topics: Animals; Azacitidine; Body Weight; Embryonic Development; Erythrocyte Count; Female; Fetal Death; Leukocyte Count; Male; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley; Sperm Count; Spermatozoa; Spleen; Testis | 1996 |
Lack of detectable major histocompatibility complex class II a beta-chain messenger ribonucleic acid in placentas of interferon-gamma- and 5-azacytidine-treated mice.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Female; Gene Expression; Genes, MHC Class I; Histocompatibility Antigens Class II; Immunohistochemistry; In Situ Hybridization; Interferon-gamma; Mice; Mice, Inbred C3H; Mice, Transgenic; Placenta; Pregnancy; Recombinant Proteins; RNA, Messenger; Stimulation, Chemical | 1997 |
Differentially expressed genes associated with 5-Aza-2'-deoxycytidine-induced hindlimb defects in the Swiss Webster mouse.
Topics: Animals; Azacitidine; Cloning, Molecular; Decitabine; Female; Gene Expression Regulation, Developmental; Hindlimb; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Pregnancy; Teratogens; Up-Regulation | 1998 |
Effects of a DNA demethylating agent--5-azacytidine--on testicular morphology during mouse embryo development.
Topics: Animals; Azacitidine; Embryonic and Fetal Development; Female; Injections, Intraperitoneal; Male; Mice; Microscopy, Electron; Pregnancy; Seminiferous Tubules; Testis | 1999 |
5-AZA-2'-deoxycytidine-induced dysmorphogenesis in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; Bone and Bones; Decitabine; Ectromelia; Female; Fetal Weight; Hindlimb; Pregnancy; Rats; Rats, Sprague-Dawley; Skull; Species Specificity | 1999 |
Changes in the placenta and in the rat embryo caused by the demethylating agent 5-azacytidine.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; DNA Methylation; Embryo, Mammalian; Female; Gestational Age; Placenta; Pregnancy; Rats; Rats, Inbred F344 | 1999 |
Nitric oxide production by pre-implantation embryos in response to embryotoxic factors.
Topics: Abortion, Spontaneous; Animals; Azacitidine; Blastocyst; Female; Humans; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nitric Oxide; Pregnancy; Pregnancy Trimester, First; Teratogens; Tumor Necrosis Factor-alpha | 2000 |
Deoxyribonucleic acid hypomethylation of male germ cells by mitotic and meiotic exposure to 5-azacytidine is associated with altered testicular histology.
Topics: Animals; Apoptosis; Azacitidine; Blotting, Western; Body Weight; Cell Separation; Cytosine; DNA; DNA Methylation; Female; Germ Cells; Male; Meiosis; Mitosis; Pregnancy; Pregnancy Outcome; Proteins; Rats; Rats, Sprague-Dawley; Spermatocytes; Spermatogonia; Testis | 2000 |
DNA hypomethylation of karyoplasts for bovine nuclear transplantation.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cattle; Cell Nucleus; Cells, Cultured; Cloning, Organism; Culture Media, Serum-Free; DNA; DNA Methylation; Embryonic and Fetal Development; Female; Fibroblasts; Nuclear Transfer Techniques; Oocytes; Pregnancy | 2001 |
Sequential observations of exencephaly and subsequent morphological changes by mouse exo utero development system: analysis of the mechanism of transformation from exencephaly to anencephaly.
Topics: Abnormalities, Drug-Induced; Anencephaly; Animals; Azacitidine; Brain; Disease Models, Animal; Female; Male; Mice; Mice, Inbred ICR; Morphogenesis; Pregnancy | 2002 |
Enhanced mortality in offsprings of male mice treated with 5-azacytidine prior to mating. Morphological changes in testes.
Topics: Animals; Azacitidine; Female; Fertility; Fetal Death; Fetal Resorption; Lethal Dose 50; Male; Mice; Pregnancy; Sexual Behavior; Spermatogenesis; Spermatozoa; Testis | 1976 |
Symptomatic hypophosphatemia secondary to 5-azacytidine therapy of acute nonlymphocytic leukemia.
Topics: Adult; Azacitidine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Phosphates; Prednisone; Pregnancy; Pregnancy Complications; Thioguanine; Vincristine | 1976 |
Morphological correlates of behavioral abnormalities in experimental congenital brain damage.
Topics: Animals; Azacitidine; Body Weight; Brain; Brain Damage, Chronic; Cerebral Cortex; Female; Frontal Lobe; Gestational Age; Hippocampus; Male; Mice; Movement Disorders; Organ Size; Pregnancy; Pyramidal Tracts; Septum Pellucidum | 1977 |
Critical periods for behavioral anomalies in mice.
Topics: Animals; Azacitidine; Behavior; Behavior, Animal; Central Nervous System; Corticosterone; Drug Evaluation, Preclinical; Environmental Exposure; Female; Fetus; Mice; Pregnancy; Psychological Tests; Rats; Species Specificity; Time Factors | 1976 |
Correlations between prenatally-induced alterations in CNS cell populations and postnatal function.
Topics: Animals; Autoradiography; Azacitidine; Behavior, Animal; Brain; Brain Damage, Chronic; Female; Fetus; Follow-Up Studies; Isotope Labeling; Mice; Pregnancy | 1977 |
The preventive influence of cysteamine on the teratogenic action of 5-azacytidine.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; Cysteamine; Female; Fetus; Pregnancy; Rats; Teratogens | 1978 |
Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides.
Topics: Adenosine Triphosphatases; Animals; Azacitidine; Bungarotoxins; Cell Differentiation; Cell Fusion; Cell Nucleus; Cells, Cultured; Deoxycytidine; DNA; Embryo, Mammalian; Female; Mice; Muscles; Myosins; Nucleoproteins; Phenotype; Pregnancy; Receptors, Cholinergic; RNA | 1978 |
Different teratogenic efficacy to mouse fetal CNS of 5-azacytidine in combination with X-irradiation depends on the sequence of successive application.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Azacitidine; Cell Survival; Female; Gestational Age; Mice; Mitosis; Pregnancy; Radiation Tolerance; Radiation-Protective Agents; Telencephalon; X-Rays | 1979 |
Behavioral consequences of interference with CNS development in the early fetal period.
Topics: Animals; Avoidance Learning; Azacitidine; Behavior, Animal; Cell Division; Central Nervous System; Embryo, Mammalian; Female; Gestational Age; Male; Mice; Motor Activity; Pregnancy; Reflex | 1979 |
Teratogenicity of 5-azacytidine in the Sprague-Dawley rat.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; DNA; Dose-Response Relationship, Drug; Female; Fetus; Mutagenicity Tests; Pregnancy; Rats; Rats, Inbred Strains; RNA; Time Factors | 1990 |
Comparison of the incidence of 5-azacytidine-induced exencephaly between MT/HokIdr and Slc:ICR mice.
Topics: Anencephaly; Animals; Azacitidine; Brain; Disease Models, Animal; Embryonic and Fetal Development; Female; Fetal Death; In Vitro Techniques; Mice; Mice, Inbred ICR; Neural Tube Defects; Pregnancy; Species Specificity | 1990 |
Inhibitory effects of cobalt chloride and cinnamaldehyde on 5-azacytidine-induced digital malformations in rats.
Topics: Abnormalities, Drug-Induced; Acrolein; Aldehydes; Analysis of Variance; Animals; Azacitidine; Body Weight; Cobalt; Female; Fetal Death; Humans; Pregnancy; Rats; Rats, Inbred Strains; Toes | 1990 |
Induction of class II MHC antigen expression on the murine placenta by 5-azacytidine correlates with fetal abortion.
Topics: Animals; Azacitidine; Blotting, Northern; Female; Fetal Death; Gene Expression; Gestational Age; Histocompatibility Antigens Class II; Immunoenzyme Techniques; Lymphocyte Activation; Major Histocompatibility Complex; Methylation; Mice; Mice, Inbred Strains; Placenta; Pregnancy; Pregnancy, Animal; Spleen; Trophoblasts | 1990 |
Synthesis and characterization of poly[d(G-z5C)]. B-Z transition and inhibition of DNA methylase.
Topics: Azacitidine; Cytidine Triphosphate; DNA (Cytosine-5-)-Methyltransferases; Female; Humans; Indicators and Reagents; Kinetics; Nucleic Acid Conformation; Placenta; Polydeoxyribonucleotides; Pregnancy; Spectrophotometry, Ultraviolet | 1985 |
Tissue-specific hypomethylation and expression of rat phosphoenolpyruvate carboxykinase gene induced by in vivo treatment of fetuses and neonates with 5-azacytidine.
Topics: Animals; Animals, Newborn; Azacitidine; DNA; Female; Fetus; Genes; Liver; Methylation; Nucleic Acid Hybridization; Phosphoenolpyruvate Carboxykinase (GTP); Pregnancy; Rats; Rats, Inbred Strains; RNA; Spleen; Transcription, Genetic | 1985 |
Mesenchymal-epithelial conversions induced by 5-azacytidine: appearance of cytokeratin Endo-A messenger RNA.
Topics: Animals; Antibodies, Monoclonal; Azacitidine; Cell Line; Connective Tissue; Epithelium; Female; Fibroblasts; Keratins; Mice; Nucleic Acid Hybridization; Pregnancy; RNA, Messenger; Teratoma; Trophoblastic Neoplasms | 1986 |
The postnatal pattern of ornithine decarboxylase activity reveals a disparity of rat brain regeneration capacity after prenatal X-ray or 5-azacytidine treatment.
Topics: Animals; Azacitidine; Brain; Female; Organ Size; Ornithine Decarboxylase; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Regeneration | 1987 |
Inhibitory effect of caffeine on 5-azacytidine-induced digital malformations in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; Caffeine; Dose-Response Relationship, Drug; Female; Fetal Death; Limb Deformities, Congenital; Methylation; Pregnancy; Rats | 1987 |
Sequential changes in DNA methylation patterns of the rat phosphoenolpyruvate carboxykinase gene during development.
Topics: Age Factors; Animals; Azacitidine; Base Sequence; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; Enzyme Induction; Female; Liver; Male; Methylation; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Pregnancy; Rats; Rats, Inbred Strains; Spleen | 1985 |
Transfer of human and murine globin-gene sequences into transgenic mice.
Topics: Animals; Azacitidine; Base Sequence; Chromosome Mapping; DNA; Embryo Transfer; Female; Galactokinase; Gene Expression Regulation; Genes; Genetic Engineering; Genetic Markers; Globins; Humans; Male; Methylation; Mice; Microinjections; Pedigree; Plasmids; Pregnancy; Zygote | 1985 |
Pycnotic degeneration of ventricular cells in embryonic brain following transplacental exposure to 5-azacytidine.
Topics: Animals; Autoradiography; Azacitidine; Brain; Cell Nucleus; Cerebral Ventricles; Cytidine; DNA; Embryo, Mammalian; Female; Male; Maternal-Fetal Exchange; Mice; Mitosis; Pregnancy; Thymidine; Triazines; Tritium | 1972 |
Effect of 5-azacytidine and 6-azauridine on the synthesis of DNA in embryonic mouse brain mitotic activity and migration of ventricular cells.
Topics: Animals; Autoradiography; Azacitidine; Azauridine; Brain; Cell Movement; Cerebral Ventricles; Cytidine; DNA; Female; Mice; Mitosis; Pregnancy; Thymidine; Time Factors; Triazines; Tritium | 1973 |