azacitidine and Pancreatic Neoplasms

azacitidine has been researched along with Pancreatic Neoplasms in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (3.17)18.2507
2000's28 (44.44)29.6817
2010's28 (44.44)24.3611
2020's5 (7.94)2.80

Authors

AuthorsStudies
Adamczyk-Grochala, J; Cappello, F; Filip, K; Lauricella, M; Lewińska, A; Marino Gammazza, A; Wnuk, M1
Ahuja, N; Azad, NS; Baretti, M; Cope, L; Durham, JN; Heumann, TR; Leatherman, J; Linden, S; Lopez-Vidal, TY; Monga, DK; O'Dwyer, PJ; Reiss, KA; Sharma, A; Sugar, EA; Weekes, CD1
Acharya, NK; Badach, J; Emery, R; Hong, YK; Jelinek, J; Joneja, U; Lin, A; Madzo, J; Platoff, R; Sandilos, G; Williamson, J; Zhang, P; Zhu, C; Zilberman, B1
Diamond, DJ; Ebelt, ND; Johnson, BL; Manuel, ER; Zuniga, E1
Bouvet, M; Hamada, K; Han, Q; Hoffman, RM; Inubushi, S; Kawaguchi, K; Nishino, H; Sugisawa, N; Tan, Y; Tashiro, Y; Unno, M; Yamamoto, J1
Han, T; Hu, H; Jiao, F; Wang, LW; Zhuo, M1
Chen, LH; Dong, JY; Hu, KF; Liu, J; Ma, LZ; Peng, H; Sun, Y; Yang, QY; Yang, XL1
Gailhouste, L; Hatada, I; Liew, LC; Nakagama, H; Ochiya, T1
Bushell, MD; Godfrey, JD; Morton, JP; Sansom, OJ; Wilczynska, A1
Ahuja, N; Cai, Y; Hu, Y; Karunasena, E; Keer, H; Lerner, L; Morreale, M; Saggi, S; Sen, R; Thakar, M; Ying Lin, W1
Guo, RD; Han, X; Li, ZJ; Tan, ZJ; Wang, YL1
Abe, K; Egawa, S; Fukushige, S; Horii, A; Kaneko, N; Karasawa, H; Miura, K; Mizuguchi, Y; Morishita, K; Motoi, F; Nagase, H; Saiki, Y; Sasaki, I; Sase, T; Shibata, C; Sunamura, M; Unno, M; Yamamura, A1
Fang, JY; Jiang, N; Lu, W; Wang, H; Wang, X; Zhang, XF1
Barthet, M; Bories, E; Calvo, E; Duconseil, P; Dusetti, N; Ewald, J; Garcia, S; Gasmi, M; Gayet, O; Gilabert, M; Giovannini, M; Goncalves, A; Iovanna, J; Loncle, C; Lopez, MB; Moutardier, V; Ouaissi, M; Poizat, F; Raoul, JL; Secq, V; Turrini, O; Viens, P1
Biankin, AV; Caldon, CE; Chang, DK; Colvin, EK; Henshall, SM; Mawson, A; Musgrove, EA; Pajic, M; Pinese, M; Scarlett, CJ; Susanto, JM; Sutherland, RL1
Bintz, J; Garcia, MN; Grasso, D; Iovanna, JL; Lomberk, G; Loncle, C; Lopez, MB; Molejon, MI; Urrutia, R1
Bu, HQ; Chen, L; Chen, ZQ; Chu, YQ; Fei, Y; Lin, SZ; Liu, DL; Pan, FP; Pan, J; Tang, J; Xu, LP; Yu, QJ; Zhang, H; Zhou, HK1
Cheng, XB; Hirata, K; Koga, A; Kohi, S; Sato, N1
Han, ZB; Hao, J; Huang, C; Jia, Z; Jiang, W; Li, Y; Ren, H; Sun, Y; Wang, H; Wang, X; Xie, K; Yang, S; Zhao, T; Zheng, C1
Ammerpohl, O; Fölsch, UR; Kalthoff, H; Koch, D; Müerköster, SS; Schäfer, H; Sipos, B; Tsao, MS; Werbing, V1
Cecconi, D; Dalla Pozza, E; Donadelli, M; Palmieri, M; Righetti, PG; Rinalducci, S; Scarpa, A; Scupoli, MT; Zolla, L1
Kumari, A; Srinivasan, R; Wig, JD1
Costanzo, C; Dandrea, M; Donadelli, M; Palmieri, M; Scarpa, A1
Jagodzinski, PP; Kozłowska, A; Lianeri, M; Lutkowska, A; Pietkiewicz, PP; Przybylski, M1
Angst, E; Dawson, DW; Eibl, G; Go, VL; Hines, OJ; Nguyen, A; Park, J; Reber, HA1
Goggins, M; Hong, SM; Li, A; Omura, N1
Brom, M; Hummel-Eisenbeiss, J; Keller, D; Keppler, D; Lyko, F; Rius, M1
Gordian, E; Miller, H; Ramachandran, K; Rocha-Lima, C; Singal, R1
Cai, HH; Gao, WT; Miao, Y; Peng, Q; Sun, YM; Yao, J; Zhao, HL1
Guo, CW; Jiang, ZZ; Li, P; Li, Q; Song, K1
Chen, J; Cui, Q; Lu, Z; Zhao, L1
Amato, E; Boninsegna, L; Dandrea, M; Debattisti, V; Falconi, M; Fumagalli, C; Malpeli, G; Pelosi, G; Scarpa, A1
Nalls, D; Rodova, M; Shankar, S; Srivastava, RK; Tang, SN1
Cogdill, AP; Cooper, ZA; Ferrone, CR; Fiedler, A; Frederick, DT; Garber, HR; Rosenberg, L; Thayer, SP; Wargo, JA; Warshaw, AL1
Goggins, M; Hong, SM; Li, A; Omura, N; Vincent, A; Walter, K; Young, A; Yu, J1
Ahn, YM; Kim, SH; Kim, YS; Lee, HY; Yi, H1
Brooks, J; Cullo, A; Davies, J; Gonda, T; Hirsch, S; Kim, S; Ludwig, T; Olive, K; Quante, M; Salas, M; Shakya, R; Szabolcs, M; Tycko, B; Wang, TC1
Bert, T; Gangsauge, S; Lubomierski, N; Münch, K; Prasnikar, N; Printz, H; Robbel, C; Simon, B1
Deng, G; Han, SW; Ho, JJ; Kim, YS; Kuan, SF; Pan, PL1
Goggins, M; Maehara, N; Sato, N; Su, GH1
Brune, K; Fukushima, N; Goggins, M; Hruban, RH; Matsubayashi, H; Sahin, F; Sato, N; Walter, KM; Yeo, CJ1
Biallek, M; Jonat, W; Klöppel, G; Lüttges, J; Maass, N; Morohoshi, T; Mundhenke, C; Nagasaki, K; Ohike, N; Zhang, M1
Chow, BK; Lee, LT; Ng, SS; Pang, RT; Yung, WH1
Astner, H; Cecconi, D; Donadelli, M; Hamdan, M; Missiaglia, E; Palmieri, M; Righetti, PG; Scarpa, A1
Alder, H; Aqeilan, RI; Cesari, R; Croce, CM; Kanematsu, T; Kuroki, T; Matsuyama, A; Mori, M; Nolli, ML; Rattan, S; Trapasso, F; Williams, NN; Yendamuri, S1
Logsdon, CD; Okami, J; Simeone, DM1
Eshleman, JR; Fukushima, N; Goggins, M; Iacobuzio-Donahue, CA; Miyagi, Y; Parker, AR; Sato, N1
Crnogorac-Jurcevic, T; Donadelli, M; Lemoine, NR; Missiaglia, E; Palmieri, M; Scarpa, A1
Furukawa, T; Horii, A; Kanai, N; Sunamura, M; Xu, S1
Abe, T; Chang, R; Dhara, S; Goggins, M; Hustinx, SR; Maitra, A; Martin, ST; Sato, N1
Abe, T; Fukushima, N; Goggins, M; Matsubayashi, H; Sato, N1
Goto, M; Hamada, T; Higashi, M; Nakamura, S; Nomoto, M; Sugai, T; Tsutsumida, H; Yonezawa, S1
Imazeki, F; Kanda, T; Nagao, K; Saisho, H; Tada, M; Yokosuka, O1
Gu, J; Ide, Y; Ito, T; Kozutsumi, Y; Miyoshi, E; Nakagawa, T; Nishida, T; Tanemura, M; Taniguchi, N; Yamamoto, H1
Goto, M; Hamada, T; Higashi, M; Nomoto, M; Tsutsumida, H; Yamada, N; Yonezawa, S1
Jiang, P; Mouri, H; Ohtsubo, K; Okada, G; Sawabu, N; Tsuchiyama, T; Watanabe, H; Yao, F1
Chen, G; Wen, Q; Zhang, FQ; Zhang, TP; Zhao, YP1
Beckhove, P; Buchler, MW; Galindo-Escobedo, LV; Geng, W; Koch, M; Krempien, R; Niethammer, AG; Rimoldi, D; Romero, P; Schmitz-Winnenthal, FH; Weitz, J; Z'graggen, K1
Chumakov, A; Gery, S; Imai, Y; Kawamata, N; Koeffler, HP; Komatsu, N; Kumagai, T; Takai, N; Wakimoto, N; Yin, D1
Blann, E; Hammons, GJ; Lyn-Cook, BD; Nichols, J; Warren, GJ1
Ammanamanchi, S; Brattain, MG; Freeman, JW; Mimari, D; Venkatasubbarao, K1
Goggins, M; Hruban, RH; Issa, JP; Skinner, H; Toyota, M; Ueki, T; Walter, KM; Yeo, CJ1
Casper, ES; Kelsen, DP; Schwartz, GK1

Trials

2 trial(s) available for azacitidine and Pancreatic Neoplasms

ArticleYear
A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence.
    Clinical epigenetics, 2022, 12-03, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; DNA Methylation; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Pancreatic Neoplasms

2022
Phase II trial of fazarabine (arabinofuranosyl-5-azacytidine) in patients with advanced pancreatic adenocarcinoma.
    Investigational new drugs, 1992, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Azacitidine; Female; Humans; Infusion Pumps; Male; Middle Aged; Pancreatic Neoplasms

1992

Other Studies

61 other study(ies) available for azacitidine and Pancreatic Neoplasms

ArticleYear
5-Azacytidine Inhibits the Activation of Senescence Program and Promotes Cytotoxic Autophagy during Trdmt1-Mediated Oxidative Stress Response in Insulinoma β-TC-6 Cells.
    Cells, 2022, 04-04, Volume: 11, Issue:7

    Topics: Animals; Antineoplastic Agents; Autophagy; Azacitidine; Insulinoma; Methyltransferases; Mice; Oxidants; Oxidative Stress; Pancreatic Neoplasms

2022
Novel treatment strategy of targeting epigenetic dysregulation in pancreatic neuroendocrine tumors.
    Surgery, 2023, Volume: 173, Issue:4

    Topics: Animals; Azacitidine; DNA; Epigenesis, Genetic; Humans; Methyltransferases; Mice; Neuroendocrine Tumors; Pancreatic Neoplasms

2023
5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Models, Animal; DNA Transposable Elements; Humans; Mice; Mice, Inbred C57BL; Pancreatic Neoplasms

2020
Triple-Methyl Blockade With Recombinant Methioninase, Cycloleucine, and Azacitidine Arrests a Pancreatic Cancer Patient-Derived Orthotopic Xenograft Model.
    Pancreas, 2021, 01-01, Volume: 50, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carbon-Sulfur Lyases; Cell Proliferation; Cycloleucine; DNA Methylation; Fibrosis; Humans; Methionine; Mice, Nude; Necrosis; Pancreatic Neoplasms; Proof of Concept Study; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2021
Synergistic effects of the combination of 5-Aza‑CdR and suberoylanilide hydroxamic acid on the anticancer property of pancreatic cancer.
    Oncology reports, 2018, Volume: 39, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Pancreatic Neoplasms; Signal Transduction; Tumor Suppressor Protein p53; Up-Regulation; Vorinostat

2018
[The Study of Methylated Regulation MicroRNA in Pancreatic Carcinoma Cell and Its Effect on Cell Proliferation,Migration and Invasion].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2017, Volume: 48, Issue:6

    Topics: Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasm Invasiveness; Pancreatic Neoplasms; Promoter Regions, Genetic

2017
Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells.
    Cell death & disease, 2018, 05-01, Volume: 9, Issue:5

    Topics: Animals; Azacitidine; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Pancreatic Neoplasms; Xenograft Model Antitumor Assays

2018
MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus.
    Cell death & disease, 2018, 05-29, Volume: 9, Issue:6

    Topics: Animals; Azacitidine; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; CpG Islands; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genetic Loci; Humans; Mice; MicroRNAs; Mutation; Neoplasm Invasiveness; Pancreatic Neoplasms; RNA, Messenger; Survival Analysis; Tumor Suppressor Protein p53

2018
A novel epigenetic modulating agent sensitizes pancreatic cells to a chemotherapy agent.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Survival; DNA (Cytosine-5-)-Methyltransferase 1; Epigenesis, Genetic; Humans; Irinotecan; Pancreas; Pancreatic Neoplasms; Topoisomerase I Inhibitors

2018
[Effect of 5-aza-2'-deoxycytidine on growth and methylation of RUNX3 gene in human pancreatic cancer cell line MiaPaca2].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Proliferation; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; RNA, Messenger

2013
Suppressed expression of NDRG2 correlates with poor prognosis in pancreatic cancer.
    Biochemical and biophysical research communications, 2013, Nov-08, Volume: 441, Issue:1

    Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Middle Aged; Negative Staining; Pancreatic Neoplasms; Prognosis; Promoter Regions, Genetic; Tumor Suppressor Proteins

2013
Effect of inhibition of MEK pathway on 5-aza-deoxycytidine-suppressed pancreatic cancer cell proliferation.
    Genetics and molecular research : GMR, 2013, Nov-18, Volume: 12, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA Methylation; Genes, Tumor Suppressor; Humans; MAP Kinase Signaling System; Pancreatic Neoplasms; Promoter Regions, Genetic; Protein Kinase Inhibitors

2013
A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor.
    Oncotarget, 2015, Jan-20, Volume: 6, Issue:2

    Topics: Animals; Azacitidine; Carcinoma, Pancreatic Ductal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Enzyme Inhibitors; Humans; Mice; Mice, Nude; Pancreatic Neoplasms; Transcriptome; Xenograft Model Antitumor Assays

2015
The epigenetic agents suberoylanilide hydroxamic acid and 5‑AZA‑2' deoxycytidine decrease cell proliferation, induce cell death and delay the growth of MiaPaCa2 pancreatic cancer cells in vivo.
    International journal of oncology, 2015, Volume: 46, Issue:5

    Topics: Animals; Antineoplastic Agents; Azacitidine; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Proliferation; Decitabine; Disease Models, Animal; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Vorinostat

2015
Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation.
    Scientific reports, 2015, Nov-30, Volume: 5

    Topics: Animals; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; Cellular Senescence; CpG Islands; DNA Methylation; DNA-Binding Proteins; Dynamin I; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Mice; Mice, Knockout; Neoplasm Proteins; Oncogenes; Pancreatic Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras)

2015
Emodin enhances the demethylation by 5-Aza-CdR of pancreatic cancer cell tumor-suppressor genes P16, RASSF1A and ppENK.
    Oncology reports, 2016, Volume: 35, Issue:4

    Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Drug Synergism; Emodin; Enkephalins; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Pancreatic Neoplasms; Promoter Regions, Genetic; Protein Precursors; Sequence Analysis, DNA; Tumor Suppressor Proteins

2016
Increased Expression of HYAL1 in Pancreatic Ductal Adenocarcinoma.
    Pancreas, 2016, Volume: 45, Issue:10

    Topics: Azacitidine; Carcinoma, Pancreatic Ductal; Decitabine; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Pancreatic Neoplasms

2016
ESE3 Inhibits Pancreatic Cancer Metastasis by Upregulating E-Cadherin.
    Cancer research, 2017, 02-15, Volume: 77, Issue:4

    Topics: Animals; Antigens, CD; Azacitidine; Cadherins; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Decitabine; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Promoter Regions, Genetic; Transcription Factors; Tumor Suppressor Proteins; Up-Regulation

2017
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases.
    International journal of cancer, 2008, Oct-15, Volume: 123, Issue:8

    Topics: Animals; Apoptosis; Azacitidine; Carcinoma, Pancreatic Ductal; Caspases; Cell Line, Tumor; Cell Nucleus; Coculture Techniques; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Etoposide; Female; Fibroblasts; Gemcitabine; Humans; Mice; Mice, SCID; Pancreatic Neoplasms; STAT1 Transcription Factor; Transfection

2008
Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study.
    Proteomics, 2009, Volume: 9, Issue:7

    Topics: Analysis of Variance; Apoptosis; Azacitidine; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Decitabine; Drug Synergism; Endocrine Gland Neoplasms; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Pancreatic Neoplasms

2009
Effect of c-MYC and E2F1 gene silencing and of 5-azacytidine treatment on telomerase activity in pancreatic cancer-derived cell lines.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2009, Volume: 9, Issue:4

    Topics: Azacitidine; Cell Line, Tumor; DNA Methylation; E2F1 Transcription Factor; Gene Silencing; Genes, myc; Humans; Pancreatic Neoplasms; Proto-Oncogene Proteins c-myc; RNA Interference; Telomerase

2009
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines.
    Nucleic acids research, 2009, Volume: 37, Issue:20

    Topics: Adenocarcinoma; Azacitidine; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA; DNA Methylation; Gene Silencing; Humans; Hydroxamic Acids; Interleukin-6; Methyl-CpG-Binding Protein 2; NF-kappa B; Pancreatic Neoplasms

2009
Increased CXCR4 expression in AsPC1 pancreatic carcinoma cells with RNA interference-mediated knockdown of DNMT1 and DNMT3B.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:4

    Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA, Neoplasm; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; Promoter Regions, Genetic; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sequence Analysis, DNA

2010
Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells.
    Pancreas, 2010, Volume: 39, Issue:5

    Topics: Azacitidine; Cell Cycle Proteins; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Pancreatic Neoplasms; Promoter Regions, Genetic; Tumor Cells, Cultured

2010
Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors.
    Cancer biology & therapy, 2010, Volume: 9, Issue:4

    Topics: Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Chromosomes, Human, Pair 19; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Dosage; Humans; Mutation; Pancreatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins

2010
Vectorial transport of nucleoside analogs from the apical to the basolateral membrane in double-transfected cells expressing the human concentrative nucleoside transporter hCNT3 and the export pump ABCC4.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:7

    Topics: Animals; Azacitidine; Biological Transport; Cell Line, Transformed; Dogs; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Nucleosides; Pancreas; Pancreatic Neoplasms; Substrate Specificity; Transfection

2010
Methylation-mediated silencing of TMS1 in pancreatic cancer and its potential contribution to chemosensitivity.
    Anticancer research, 2010, Volume: 30, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; CARD Signaling Adaptor Proteins; Cell Line, Tumor; Cytoskeletal Proteins; Deoxycytidine; DNA Methylation; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Gene Silencing; Humans; Pancreatic Neoplasms; Promoter Regions, Genetic; Taxoids; Transfection

2010
Aberrant methylation frequency of TNFRSF10C promoter in pancreatic cancer cell lines.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2011, Volume: 10, Issue:1

    Topics: Apoptosis; Azacitidine; Decitabine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression; GPI-Linked Proteins; Humans; Hydroxamic Acids; Pancreatic Neoplasms; Promoter Regions, Genetic; Receptors, Tumor Necrosis Factor, Member 10c; Restriction Mapping; Sequence Analysis, DNA; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors

2011
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer.
    Cancer biology & therapy, 2011, Sep-01, Volume: 12, Issue:5

    Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; Endothelial Cells; Epithelial-Mesenchymal Transition; Heparitin Sulfate; Histones; Humans; Hydroxamic Acids; Methylation; Pancreatic Neoplasms; RNA, Messenger; Sequence Analysis, DNA; Snail Family Transcription Factors; Sulfotransferases; Transcription Factors; Transcriptional Activation

2011
Aberrant methylation of RASSF2A in human pancreatic ductal adenocarcinoma and its relation to clinicopathologic features.
    Pancreas, 2012, Volume: 41, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Line; China; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Pancreatic Neoplasms; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Suppressor Proteins

2012
Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors.
    BMC cancer, 2011, Aug-12, Volume: 11

    Topics: Adult; Aged; Azacitidine; Case-Control Studies; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Linear Models; Male; Middle Aged; Pancreatic Neoplasms; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Statistics, Nonparametric; Tumor Suppressor Proteins; Up-Regulation

2011
Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromatin; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; MicroRNAs; Neoplasm Invasiveness; Neoplastic Stem Cells; Pancreatic Neoplasms; Spheroids, Cellular; Tumor Stem Cell Assay; Up-Regulation; Vorinostat

2011
Targeting the MAGE A3 antigen in pancreatic cancer.
    Surgery, 2012, Volume: 152, Issue:3 Suppl 1

    Topics: Adenocarcinoma; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cytokines; Decitabine; Deoxycytidine; DNA Methylation; Gemcitabine; Humans; Hydroxamic Acids; Immunotherapy; Male; Neoplasm Proteins; Pancreas; Pancreatic Neoplasms; Receptors, Antigen, T-Cell; T-Lymphocytes; Testis; Valproic Acid

2012
Unlike pancreatic cancer cells pancreatic cancer associated fibroblasts display minimal gene induction after 5-aza-2'-deoxycytidine.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: ADAM Proteins; ADAM12 Protein; Azacitidine; Base Sequence; Blotting, Western; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Genetic Association Studies; Humans; Immunohistochemistry; Male; Membrane Proteins; Middle Aged; Molecular Sequence Data; Pancreatic Neoplasms; RNA, Messenger; Sequence Analysis, DNA; Up-Regulation

2012
Haloperidol induces demethylation and expression of the dual specificity phosphatase 6 gene in MIA PaCa-2 human pancreatic cancer cells.
    Life sciences, 2012, Dec-17, Volume: 91, Issue:25-26

    Topics: Antipsychotic Agents; Azacitidine; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 6; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Haloperidol; Humans; Introns; Molecular Sequence Data; Pancreatic Neoplasms

2012
Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.
    Cancer research, 2013, Jan-15, Volume: 73, Issue:2

    Topics: Animals; Azacitidine; Carcinoma, Pancreatic Ductal; Decitabine; DNA Methylation; Female; Humans; Male; Mice; Mice, Transgenic; Pancreatic Neoplasms; Stromal Cells

2013
Expression spectrum and methylation-dependent regulation of melanoma antigen-encoding gene family members in pancreatic cancer cells.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2002, Volume: 2, Issue:2

    Topics: Adult; Aged; Antigens, Neoplasm; Azacitidine; Culture Techniques; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Expression; Gene Expression Regulation; Humans; Male; Melanoma; Middle Aged; Pancreatic Neoplasms; Tumor Cells, Cultured; Up-Regulation

2002
Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.
    International journal of oncology, 2003, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Azacitidine; Base Sequence; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Mucin 5AC; Mucin-2; Mucins; Neoplasm Invasiveness; Neoplasm Proteins; Pancreas; Pancreatic Neoplasms; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm

2003
Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness.
    Journal of the National Cancer Institute, 2003, Feb-19, Volume: 95, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinases; Methylation; Neoplasm Invasiveness; Pancreatic Neoplasms; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2003
Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:4

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Cyclin D2; Cyclins; Decitabine; Digestive System; DNA Methylation; Female; Humans; Male; Middle Aged; Pancreatic Juice; Pancreatic Neoplasms; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA; Transfection

2003
Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas.
    Cancer letters, 2003, Sep-25, Volume: 199, Issue:2

    Topics: Acetylation; Aged; Azacitidine; Carcinoma, Pancreatic Ductal; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Lymphatic Metastasis; Male; Middle Aged; Pancreatic Neoplasms; Promoter Regions, Genetic; Proteins; Serpins; Tumor Cells, Cultured; Up-Regulation

2003
CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene.
    Molecular endocrinology (Baltimore, Md.), 2004, Volume: 18, Issue:2

    Topics: Adenocarcinoma; Animals; Azacitidine; Base Composition; Base Sequence; Cattle; Cells, Cultured; CpG Islands; Cytosine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Drosophila; Enzyme Inhibitors; Gene Expression Regulation; Humans; Molecular Sequence Data; Pancreatic Neoplasms; Promoter Regions, Genetic; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Regulatory Sequences, Nucleic Acid; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcription Factors

2004
Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine.
    Electrophoresis, 2003, Volume: 24, Issue:24

    Topics: Actin Depolymerizing Factors; Azacitidine; Carcinoma, Pancreatic Ductal; Cell Division; Contractile Proteins; Cyclin-Dependent Kinase Inhibitor p16; Cyclophilin A; Cystatin B; Cystatins; Decitabine; DNA Methylation; Humans; Mass Spectrometry; Microfilament Proteins; Pancreatic Neoplasms; Profilins; Promoter Regions, Genetic; Proteomics; Rosaniline Dyes; Superoxide Dismutase; Tumor Cells, Cultured

2003
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Adenocarcinoma; Alleles; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Separation; Cell Transformation, Neoplastic; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA, Complementary; Exons; Flow Cytometry; Genes, Tumor Suppressor; Humans; Loss of Heterozygosity; Oxidoreductases; Pancreatic Neoplasms; Promoter Regions, Genetic; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tumor Suppressor Proteins; WW Domain-Containing Oxidoreductase

2004
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer.
    Cancer research, 2004, Aug-01, Volume: 64, Issue:15

    Topics: Adenocarcinoma; Apoptosis; Azacitidine; Cell Hypoxia; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Glucose Transport Proteins, Facilitative; Humans; Insulin-Like Growth Factor Binding Protein 3; Membrane Proteins; Monosaccharide Transport Proteins; Pancreas; Pancreatic Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins; Tumor Cells, Cultured

2004
Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma.
    Oncogene, 2005, Jan-27, Volume: 24, Issue:5

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Decitabine; DNA Primers; Glycoproteins; Humans; Hydroxamic Acids; Loss of Heterozygosity; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous

2005
Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway.
    Oncogene, 2005, Jan-06, Volume: 24, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Cisplatin; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Gemcitabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Interferons; Pancreatic Neoplasms; Signal Transduction

2005
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer.
    Journal of human genetics, 2005, Volume: 50, Issue:4

    Topics: Acetylation; Adenocarcinoma; Azacitidine; Base Sequence; Carcinoma, Pancreatic Ductal; Cell Differentiation; CpG Islands; DNA Methylation; Dual Specificity Phosphatase 6; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Molecular Sequence Data; Neoplasm Invasiveness; Pancreatic Neoplasms; Protein Tyrosine Phosphatases; Tumor Cells, Cultured

2005
Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms.
    Cancer biology & therapy, 2005, Volume: 4, Issue:7

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Carrier Proteins; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Membrane Glycoproteins; Pancreas; Pancreatic Ducts; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2005
Epigenetic down-regulation of CDKN1C/p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Jul-01, Volume: 11, Issue:13

    Topics: Adenocarcinoma, Mucinous; Adenocarcinoma, Papillary; Azacitidine; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cluster Analysis; Cyclin-Dependent Kinase Inhibitor p57; Decitabine; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Immunohistochemistry; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction

2005
Mapping of the methylation pattern of the MUC2 promoter in pancreatic cancer cell lines, using bisulfite genomic sequencing.
    Cancer letters, 2005, Sep-28, Volume: 227, Issue:2

    Topics: Azacitidine; Colon; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mucin-2; Mucins; Pancreatic Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Sequence Analysis, DNA; Sp1 Transcription Factor; Sulfites; Tumor Cells, Cultured

2005
5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines.
    Oncology reports, 2005, Volume: 14, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Azacitidine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Decitabine; DNA; DNA Methylation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluorouracil; HeLa Cells; Humans; Liver Neoplasms; Pancreatic Neoplasms; Prognosis; Time Factors; Treatment Outcome; Trypan Blue

2005
Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer.
    Biochemical and biophysical research communications, 2006, Mar-10, Volume: 341, Issue:2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Northern; Butyrates; Cell Line, Tumor; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Male; Models, Biological; N-Acetylglucosaminyltransferases; Oligonucleotide Array Sequence Analysis; Oligosaccharides; Pancreas; Pancreatic Neoplasms; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation

2006
MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer.
    International journal of cancer, 2006, Oct-15, Volume: 119, Issue:8

    Topics: Azacitidine; Cell Line, Tumor; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Histones; Humans; Hydroxamic Acids; Mucin-2; Mucins; Pancreatic Neoplasms; Promoter Regions, Genetic; RNA, Messenger

2006
Diagnostic utility of aberrant methylation of tissue factor pathway inhibitor 2 in pure pancreatic juice for pancreatic carcinoma.
    Cancer science, 2006, Volume: 97, Issue:11

    Topics: Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Cell Line, Tumor; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Male; Middle Aged; Pancreatic Juice; Pancreatic Neoplasms; Pancreatitis, Chronic; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm

2006
[Expression of S100A2 in secondarily radioresistant pancreatic cancer cells and significance thereof].
    Zhonghua yi xue za zhi, 2006, Oct-31, Volume: 86, Issue:40

    Topics: Azacitidine; Cell Cycle; Cell Line, Tumor; Cell Survival; Chemotactic Factors; Decitabine; Down-Regulation; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S100 Proteins

2006
Potential target antigens for immunotherapy in human pancreatic cancer.
    Cancer letters, 2007, Jul-18, Volume: 252, Issue:2

    Topics: Adenocarcinoma; Antigens, Neoplasm; Azacitidine; Base Sequence; DNA Primers; Humans; Immunotherapy; Pancreatic Neoplasms

2007
Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells.
    International journal of cancer, 2007, Aug-01, Volume: 121, Issue:3

    Topics: Annexin A5; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Decitabine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Hydroxamic Acids; Methylation; Pancreatic Neoplasms; Vorinostat

2007
Increased DT-diaphorase activity in transformed and tumorigenic pancreatic acinar cells.
    Cancer letters, 1995, Sep-04, Volume: 96, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Genes, ras; In Vitro Techniques; Methylation; NAD(P)H Dehydrogenase (Quinone); NADH Dehydrogenase; Pancreatic Neoplasms; Rats; Rats, Inbred F344

1995
Reversion of transcriptional repression of Sp1 by 5 aza-2' deoxycytidine restores TGF-beta type II receptor expression in the pancreatic cancer cell line MIA PaCa-2.
    Cancer research, 2001, Aug-15, Volume: 61, Issue:16

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Azacitidine; Cell Division; Chloramphenicol O-Acetyltransferase; Decitabine; DNA Modification Methylases; DNA, Complementary; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Pancreatic Neoplasms; Plicamycin; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Sp1 Transcription Factor; Transcriptional Activation; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured

2001
Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma.
    Cancer research, 2001, Dec-01, Volume: 61, Issue:23

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; CpG Islands; Cyclin G; Cyclin G1; Cyclins; DNA Methylation; Enkephalins; Humans; Microsatellite Repeats; Middle Aged; Pancreatic Neoplasms; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction

2001