azacitidine and Osteosarcoma

azacitidine has been researched along with Osteosarcoma in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's3 (13.64)18.2507
2000's5 (22.73)29.6817
2010's11 (50.00)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Barkauskas, DA; Chow, WY; Farrar, JE; Gerhard, D; Gorlick, R; Guerra, R; Guidry Auvil, JM; Hicks, MJ; Lau, CC; Man, TK; Meltzer, P; Nakka, M; Ng, PKS; Shen, J; Sun, JM; Taylor, AM; Xu, G; Yu, A1
Bouvet, M; Han, Q; Hayashi, K; Higuchi, T; Hoffman, RM; Igarashi, K; Kimura, H; Kuchipudi, S; Miwa, S; Oshiro, H; Singh, SR; Sugisawa, N; Tan, Y; Tsuchiya, H; Yamamoto, J; Yamamoto, N1
Cheng, T; Guo, W; Ruan, F; Wei, B; Xiang, M; Xu, X1
Desiderio, V; La Noce, M; Lombardi, A; Mele, L; Paino, F; Papaccio, F; Papaccio, G; Regad, T; Tirino, V1
Barøy, T; Myklebost, O; Skårn, M; Stratford, EW1
Guo, QN; Huang, Y; Li, Y; Lv, Y; Meng, G1
Chen, H; Geng, P; Huang, L; Jiang, W; Li, Y; Lin, X; Liu, J; Su, B; Wang, Y; Yao, J1
Li, B; Li, H; Sun, L; Ye, Z; Yuan, L; Zhang, J; Zhu, X1
Chen, WZ; Chen, XY; Huang, SH; Liu, JM; Liu, ZL; Long, XH; Peng, AF; Zhang, ZH; Zhou, YF1
Katula, KS; Rumph, C; Vaidya, H1
Clemens, D; Dirksen, U; Hotfilder, M; Klco-Brosius, S; Pettke, A; Potratz, J; Schaefer, C1
Huang, G; Kleinerman, ES; Koshkina, NV1
Li, L; Liu, X; Tu, B; Wang, D; Wang, H; Wang, L; Zheng, Z; Zhu, WG1
Burkett, MW; Delosh, RM; Han, B; Hite, KM; Hollingshead, MG; Hose, CD; Millione, A; Monks, A; Nagashima, K; Newton, DL; Saini, V; Scudiero, DA; Shah, J; Shoemaker, RH; Silvers, TE1
Hirschfeld, S; Ho, PT; Pazdur, R; Smith, M1
Honoki, K; Mii, Y; Mori, T; Takakura, Y; Tsujiuchi, T; Tsutsumi, M; Yoshitani, K1
Deocaris, CC; Hasan, K; Ishii, T; Kaul, SC; Kaur, K; Sugihara, T; Wadhwa, R; Widodo, N; Yaguchi, T; Yamasaki, K1
Al-Romaih, K; Sadikovic, B; Squire, JA; Wang, Y; Yoshimoto, M; Zielenska, M1
Glaubiger, DL; LeVine, AS; Poplack, DG; Reaman, GH; Srinivasan, U1
Benvenuto, G; Bruni, CB; Chiariotti, L; Colantuoni, V; Rossi, E; Salvatore, P; Zarrilli, R1
Locklin, RM; Oreffo, RO; Triffitt, JT1
Angle, CR; Swanson, SA; Thomas, DJ1

Reviews

1 review(s) available for azacitidine and Osteosarcoma

ArticleYear
Regulatory approvals of pediatric oncology drugs: previous experience and new initiatives.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-15, Volume: 21, Issue:6

    Topics: Antineoplastic Agents; Azacitidine; Child; Child, Preschool; Drug Approval; Humans; Leukemia, Myeloid, Acute; Methotrexate; Neuroblastoma; Osteosarcoma; Pediatrics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide; United States; United States Food and Drug Administration; Vindesine

2003

Other Studies

21 other study(ies) available for azacitidine and Osteosarcoma

ArticleYear
The Role of FAS Receptor Methylation in Osteosarcoma Metastasis.
    International journal of molecular sciences, 2023, Jul-29, Volume: 24, Issue:15

    Topics: Animals; Azacitidine; Bone Neoplasms; Cell Line, Tumor; CpG Islands; DNA Methylation; fas Receptor; Mice; Osteosarcoma

2023
The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model.
    Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:2

    Topics: Adolescent; Animals; Antineoplastic Agents; Azacitidine; Bone Neoplasms; Carbon-Sulfur Lyases; Combined Modality Therapy; Disease Models, Animal; Doxorubicin; Drug Resistance, Neoplasm; Heterografts; Humans; Male; Mice; Mice, Nude; Osteosarcoma; Tumor Burden; Xenograft Model Antitumor Assays

2020
The Na+/K+ ATPase Inhibitor Ouabain Attenuates Stemness and Chemoresistance of Osteosarcoma Cells.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Dec-11, Volume: 25

    Topics: Azacitidine; Bone Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Neoplasm Invasiveness; Neoplastic Stem Cells; Osteosarcoma; Ouabain; Sodium-Potassium-Exchanging ATPase

2019
HDAC2 depletion promotes osteosarcoma's stemness both in vitro and in vivo: a study on a putative new target for CSCs directed therapy.
    Journal of experimental & clinical cancer research : CR, 2018, Dec-03, Volume: 37, Issue:1

    Topics: Animals; Azacitidine; Bone Neoplasms; Cell Line, Tumor; DNA Methylation; Heterografts; Histone Deacetylase 2; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Osteosarcoma; Transfection; Valproic Acid

2018
Epigenetic regulation and functional characterization of microRNA-142 in mesenchymal cells.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Azacitidine; Base Pairing; Base Sequence; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation; Gene Silencing; Humans; MicroRNAs; Molecular Sequence Data; Osteosarcoma; Promoter Regions, Genetic; RNA Precursors; RNA, Antisense; Transcription, Genetic; Tumor Stem Cell Assay

2013
Epigenetic regulation of the pro-apoptosis gene TSSC3 in human osteosarcoma cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2014, Volume: 68, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Bone Neoplasms; Caspase 3; Cell Line, Tumor; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Nuclear Proteins; Osteosarcoma; Promoter Regions, Genetic; Up-Regulation

2014
Enhancement of radiosensitivity by 5-Aza-CdR through activation of G2/M checkpoint response and apoptosis in osteosarcoma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:5

    Topics: 14-3-3 Proteins; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Bone Neoplasms; Cell Division; Cell Line, Tumor; Checkpoint Kinase 2; Death-Associated Protein Kinases; Decitabine; Exoribonucleases; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Osteosarcoma; Radiation Tolerance

2014
Induction of a specific CD8+ T-cell response to cancer/testis antigens by demethylating pre-treatment against osteosarcoma.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Bone Neoplasms; CD8-Positive T-Lymphocytes; Cell Proliferation; Decitabine; Female; Flow Cytometry; Humans; Immunotherapy; Membrane Proteins; Mice; Mice, SCID; Neoplasm Proteins; Osteosarcoma; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured

2014
Demethylation-mediated miR-129-5p up-regulation inhibits malignant phenotype of osteogenic osteosarcoma by targeting Homo sapiens valosin-containing protein (VCP).
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:5

    Topics: Adenosine Triphosphatases; Azacitidine; Carcinogenesis; Cell Cycle Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Osteosarcoma; Signal Transduction; Valosin Containing Protein

2015
Inactivation of the WNT5A Alternative Promoter B Is Associated with DNA Methylation and Histone Modification in Osteosarcoma Cell Lines U2OS and SaOS-2.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Azacitidine; Bone Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; DNA, Neoplasm; Exons; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histone Code; Humans; Luciferases, Renilla; Methylation; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteosarcoma; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Transfection; Wnt Proteins; Wnt Signaling Pathway; Wnt-5a Protein

2016
Suberanilohydroxamic acid (vorinostat) synergistically enhances the cytotoxicity of doxorubicin and cisplatin in osteosarcoma cell lines.
    Anti-cancer drugs, 2016, Volume: 27, Issue:10

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Doxorubicin; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Osteosarcoma; Vorinostat

2016
Fas expression in metastatic osteosarcoma cells is not regulated by CpG island methylation.
    Oncology research, 2009, Volume: 18, Issue:1

    Topics: Azacitidine; Cell Line, Tumor; Cell Survival; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Gene Expression Regulation, Neoplastic; Humans; Introns; Neoplasm Metastasis; Osteosarcoma; Promoter Regions, Genetic

2009
5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lung Neoplasms; Osteosarcoma; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-mdm2; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130

2012
Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; Femoral Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Proteins; Neoplastic Stem Cells; Osteosarcoma; Vincristine

2012
Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines.
    Molecular carcinogenesis, 2004, Volume: 39, Issue:1

    Topics: Adenocarcinoma; Animals; Azacitidine; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Fibroblasts; Gene Silencing; Histiocytoma, Benign Fibrous; Lung Neoplasms; Neoplasms; Osteosarcoma; Promoter Regions, Genetic; Rats; RNA, Messenger; Sulfites; TATA Box; Tumor Cells, Cultured

2004
Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2007, Volume: 62, Issue:3

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Biomarkers; Biomarkers, Tumor; Cell Line, Tumor; Cellular Senescence; Chromatin; Chromatin Assembly and Disassembly; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, p53; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Lipoproteins; Membrane Proteins; Molecular Chaperones; Osteosarcoma; Tumor Suppressor Proteins

2007
Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells.
    Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:5

    Topics: Animals; Apoptosis; Azacitidine; Blotting, Western; Bone Neoplasms; Cell Cycle Proteins; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Nude; Nuclear Proteins; Osteoblasts; Osteosarcoma; RNA, Small Interfering; Transplantation, Heterologous; Tumor Cells, Cultured

2008
Phase II study of 5-azacytidine in sarcomas of bone.
    American journal of clinical oncology, 1982, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Azacitidine; Bone Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukocyte Count; Male; Neoplasm Metastasis; Neutropenia; Osteosarcoma; Platelet Count; Sarcoma, Ewing; Thrombocytopenia

1982
Activation of the galectin-1 (L-14-I) gene from nonexpressing differentiated cells by fusion with undifferentiated and tumorigenic cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:7

    Topics: Alleles; Animals; Azacitidine; Base Sequence; Cell Differentiation; Cell Fusion; Cells, Cultured; Galectin 1; Gene Expression Regulation, Neoplastic; Genes, Dominant; Hemagglutinins; Humans; Liver; Liver Neoplasms, Experimental; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; Osteosarcoma; Rats; Tumor Cells, Cultured

1994
Modulation of osteogenic differentiation in human skeletal cells in Vitro by 5-azacytidine.
    Cell biology international, 1998, Volume: 22, Issue:3

    Topics: Alkaline Phosphatase; Azacitidine; Biomarkers; Bone Marrow Cells; Bone Neoplasms; Cell Differentiation; Cells, Cultured; DNA; DNA Methylation; Female; Humans; Male; Middle Aged; Osteoblasts; Osteogenesis; Osteosarcoma; Proteins; Stromal Cells; Tumor Cells, Cultured

1998
Effect of 5-azacytidine on metallothionein inducibility and sensitivity to lethality of cadmium in rat osteosarcoma (ROS 17/2.8) cells.
    Toxicology, 1990, Dec-17, Volume: 65, Issue:1-2

    Topics: Animals; Azacitidine; Cadmium; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Metallothionein; Osteosarcoma; Rats; Tumor Cells, Cultured

1990