Compounds > azacitidine

azacitidine and Osteoarthritis

azacitidine has been researched along with Osteoarthritis in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (33.33)	29.6817
2010's	8 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Huang, C; Wang, Q; Zhang, C; Zhao, L	1
Chang, JK; Chang, LH; Chen, CH; Fu, YC; Ho, ML; Hung, SH; Lee, HY; Lin, YS; Wang, GJ; Wu, SC	1
Gay, RE; Gay, S; Karouzakis, E; Michel, BA; Neidhart, M	1
Gay, RE; Gay, S; Karouzakis, E; Neidhart, M; Schumann, GG	1
Gürses, S; Kavas, A; Keskin, D; Ozdemir, M; Tezcaner, A	1
Cheng, YJ; Huang, CB; Niu, SP; Yang, T; Zhao, LK	1
Barter, MJ; Bui, C; Galler, M; Reynard, LN; Rowan, AD; Scott, JL; Xu, Y; Young, DA	1
Im, GI; Kim, KI; Park, YS	1
Boyle, DL; Firestein, GS; Nakano, K	1
Banerjee, S; Cagatay, ST; Kavas, A; Keskin, D; Tezcaner, A	1
Chang, JK; Chen, CH; Chung, YH; Ho, ML; Hung, SH; Wang, GJ; Wu, SC	1
Iliopoulos, D; Malizos, KN; Tsezou, A	1

Other Studies

12 other study(ies) available for azacitidine and Osteoarthritis

Article	Year
Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis. Clinical rheumatology, 2017, Volume: 36, Issue:10 Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azacitidine; Cartilage, Articular; Cells, Cultured; Chemokine CX3CL1; Chondrocytes; Connective Tissue Growth Factor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Humans; Ligands; Male; Middle Aged; Osteoarthritis; Protein Domains; RNA, Messenger; Sample Size; Sequence Analysis, DNA; Tibia; TNF Receptor-Associated Factor 1	2017
Parathyroid hormone 1-34 inhibits terminal differentiation of human articular chondrocytes and osteoarthritis progression in rats. Arthritis and rheumatism, 2009, Volume: 60, Issue:10 Topics: Adult; Animals; Azacitidine; Cartilage, Articular; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chondrocytes; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Female; Glycosaminoglycans; Humans; Injections, Intra-Articular; Male; Middle Aged; Osteoarthritis; Papain; Parathyroid Hormone; Rats; Rats, Sprague-Dawley	2009
DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. Arthritis and rheumatism, 2009, Volume: 60, Issue:12 Topics: Arthritis, Rheumatoid; Azacitidine; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Fibroblasts; Gene Expression; Gene Silencing; Humans; Long Interspersed Nucleotide Elements; Oligonucleotide Array Sequence Analysis; Osteoarthritis; Synovial Membrane	2009
Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts. Arthritis and rheumatism, 2010, Volume: 62, Issue:9 Topics: Arthritis, Rheumatoid; Azacitidine; Cells, Cultured; Down-Regulation; Exodeoxyribonucleases; Fibroblasts; Flow Cytometry; Gene Expression; Gene Silencing; Humans; Immunohistochemistry; Long Interspersed Nucleotide Elements; Oligonucleotide Array Sequence Analysis; Osteoarthritis; Phosphoproteins; RNA, Messenger; RNA, Small Interfering; Synovial Membrane; Transfection	2010
In vitro investigation and biomechanical modeling of the effects of PLF-68 on osteoarthritis in a three-dimensional model. Biomechanics and modeling in mechanobiology, 2011, Volume: 10, Issue:5 Topics: Animals; Azacitidine; Biomechanical Phenomena; Cartilage, Articular; Chondrocytes; In Vitro Techniques; Models, Theoretical; Osteoarthritis; Poloxamer; Rats; Rats, Sprague-Dawley	2011
[The role of promoter CpG islands methylation of leptin gene in osteoarthritis]. Zhonghua nei ke za zhi, 2011, Volume: 50, Issue:1 Topics: Adult; Aged; Azacitidine; Case-Control Studies; Cells, Cultured; Chondrocytes; CpG Islands; DNA Methylation; Female; Humans; Leptin; Male; Middle Aged; Osteoarthritis; Promoter Regions, Genetic	2011
cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:7 Topics: Azacitidine; Base Sequence; Calcium; Chondrocytes; CpG Islands; Cyclic AMP Response Element-Binding Protein; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; Enzyme Inhibitors; Humans; In Vitro Techniques; Matrix Metalloproteinase 13; Osteoarthritis; Promoter Regions, Genetic; RNA, Small Interfering; Up-Regulation	2012
Changes in the epigenetic status of the SOX-9 promoter in human osteoarthritic cartilage. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2013, Volume: 28, Issue:5 Topics: Azacitidine; Base Sequence; Blotting, Western; DNA Methylation; DNA Primers; Epigenesis, Genetic; Humans; Osteoarthritis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; SOX9 Transcription Factor; Transcription Factors	2013
Regulation of DNA methylation in rheumatoid arthritis synoviocytes. Journal of immunology (Baltimore, Md. : 1950), 2013, Feb-01, Volume: 190, Issue:3 Topics: Adipokines; Arthritis, Rheumatoid; Azacitidine; Chitinase-3-Like Protein 1; Collagen Type I; Collagen Type I, alpha 1 Chain; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Interleukin-1beta; Lectins; Long Interspersed Nucleotide Elements; Osteoarthritis; RNA, Messenger; Synovial Membrane	2013
Potential of Raloxifene in reversing osteoarthritis-like alterations in rat chondrocytes: an in vitro model study. Journal of biosciences, 2013, Volume: 38, Issue:1 Topics: Aggrecans; Alkaline Phosphatase; Animals; Apoptosis; Azacitidine; Biomarkers; Bone Density Conservation Agents; Cartilage, Articular; Caspase 3; Chondrocytes; Collagen Type II; Dose-Response Relationship, Drug; Gene Expression; Matrix Metalloproteinases; Models, Biological; Osteoarthritis; Primary Cell Culture; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley	2013
A novel terminal differentiation model of human articular chondrocytes in three-dimensional cultures mimicking chondrocytic changes in osteoarthritis. Cell biology international, 2006, Volume: 30, Issue:3 Topics: Alkaline Phosphatase; Apoptosis; Azacitidine; Cartilage, Articular; Cell Culture Techniques; Cell Differentiation; Cell Size; Chondrocytes; Collagen Type II; Collagen Type X; Flow Cytometry; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Models, Biological; Osteoarthritis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2006
Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention. Annals of the rheumatic diseases, 2007, Volume: 66, Issue:12 Topics: Acetylation; Adult; Aged; Aged, 80 and over; Analysis of Variance; Azacitidine; Blotting, Western; Cartilage, Articular; Case-Control Studies; Chondrocytes; Decitabine; DNA Methylation; DNA Modification Methylases; Female; Gene Expression; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Knee Joint; Leptin; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Middle Aged; Osteoarthritis; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering	2007