Compounds > azacitidine

azacitidine and Mesothelioma

azacitidine has been researched along with Mesothelioma in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's3 (18.75)18.2507
2000's5 (31.25)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, MC; Kim, NY; Kim, Y1
Aoe, K; Date, H; Fujimoto, N; Kimura, K; Kishimoto, T; Kubo, T; Otani, H; Pass, HI; Sano, Y; Soh, J; Suehisa, H; Toyooka, S; Tsukuda, K; Yamamoto, H1
Amatori, S; Bagaloni, I; Fanelli, M; Viti, D1
Hamada, H; Hirai, S; Kato, K; Sakuragi, N; Takenouchi, M; Yagita, H1
Amati, M; Neuzil, J; Nocchi, L; Saccucci, F; Santarelli, L; Tomasetti, M1
Blanquart, C; Boutin, B; Fonteneau, JF; Grégoire, M; Gueugnon, F; Guillot, F; Leclercq, S; Padieu, M; Pouliquen, D; Rogel, A1
Blanquart, C; Fonteneau, JF; Grégoire, M; Gueugnon, F; Panterne, C; Roulois, D1
Chen, GA; Figg, WD; Fischette, MR; Hancox, A; Hong, JA; Kunst, TF; Li, X; Murgo, AJ; Nguyen, DM; Pishchik, V; Schrump, DS; Steinberg, SM; Zhao, M1
Green, MR; Kern, JA; Kindler, HL; Kratzke, MG; Kratzke, RA; Vogelzang, NJ; Vokes, EE; Wang, X; Wong, L1
Antman, KH; Cirrincione, C; Citron, ML; Corson, JM; Green, MR; Harmon, DC; Herndon, JE; Suzuki, Y; Yogelzang, NJ1
Aisner, J; Carey, R; Corson, JM; Green, MR; Harmon, DC; Herndon, JE; Samuels, BL; Suzuki, Y; Vogelzang, NJ1
Altomonte, M; Cacciotti, P; Cebon, J; Colizzi, F; Coral, S; Gaudino, G; Jungbluth, A; Libener, R; Maio, M; Maraskovsky, E; Martini, F; Mutti, L; Natali, L; Sigalotti, L; Tognon, M; Vianale, G1
Bocchetta, M; Carbone, M; Gazdar, AF; Minna, JD; Shivapurkar, N; Toyooka, KO; Toyooka, S1
Chahinian, AP; Holland, JF; Mandel, EM1
Chahinian, AP; Holland, JF; Mandel, EM; Suzuki, Y1
Dhingra, HM; Hong, WK; Murphy, WK; Raber, MN; Winn, RJ1

Trials

4 trial(s) available for azacitidine and Mesothelioma

ArticleYear
Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Oct-01, Volume: 12, Issue:19

    Topics: Adult; Aged; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Decitabine; DNA Modification Methylases; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Membrane Proteins; Mesothelioma; Middle Aged; Neoplasm Proteins; Pleural Neoplasms; Transcriptional Activation

2006
Dihydro-5-azacytidine in malignant mesothelioma. A phase II trial demonstrating activity accompanied by cardiac toxicity. Cancer and Leukemia Group B.
    Cancer, 1997, Jun-01, Volume: 79, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arrhythmias, Cardiac; Azacitidine; Chest Pain; Female; Humans; Male; Mesothelioma; Middle Aged; Pleural Neoplasms

1997
Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B.
    Cancer, 1998, Apr-15, Volume: 82, Issue:8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chest Pain; Cisplatin; Female; Humans; Leukopenia; Male; Mesothelioma; Middle Aged; Pleural Neoplasms; Prognosis; Survival Analysis

1998
Phase II trial of 5,6-dihydro-5-azacytidine in pleural malignant mesothelioma.
    Investigational new drugs, 1991, Volume: 9, Issue:1

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Drug Evaluation; Female; Humans; Male; Mesothelioma; Middle Aged; Pleural Neoplasms

1991

Other Studies

12 other study(ies) available for azacitidine and Mesothelioma

ArticleYear
Hypomethylation reduced the aggressive potential of human malignant mesothelioma cells.
    Cancer gene therapy, 2016, Volume: 23, Issue:12

    Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Survival; CpG Islands; Decitabine; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant

2016
The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas.
    Oncology reports, 2008, Volume: 20, Issue:5

    Topics: Azacitidine; Bone Morphogenetic Protein 6; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression; Growth Differentiation Factor 10; Humans; Japan; Mesothelioma; Pleural Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; United States

2008
Premature senescence induced by DNA demethylating agent (Decitabine) as therapeutic option for malignant pleural mesothelioma.
    Lung cancer (Amsterdam, Netherlands), 2011, Volume: 71, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cellular Senescence; Decitabine; DNA Methylation; Humans; Mesothelioma; Pleural Neoplasms

2011
Epigenetic modulation enhances the therapeutic effect of anti-IL-13R(alpha)2 antibody in human mesothelioma xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, May-01, Volume: 17, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Combined Modality Therapy; Decitabine; Drug Synergism; Epigenesis, Genetic; Female; HCT116 Cells; Humans; Immunotherapy; Interleukin-13 Receptor alpha2 Subunit; Mesothelioma; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Xenograft Model Antitumor Assays

2011
Thrombomodulin is silenced in malignant mesothelioma by a poly(ADP-ribose) polymerase-1-mediated epigenetic mechanism.
    The Journal of biological chemistry, 2011, Jun-03, Volume: 286, Issue:22

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Cell Line; Decitabine; DNA Methylation; Epithelium; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Mesothelioma; Middle Aged; Neoplasm Proteins; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Thrombomodulin

2011
A 5-aza-2'-deoxycytidine/valproate combination induces cytotoxic T-cell response against mesothelioma.
    The European respiratory journal, 2011, Volume: 38, Issue:5

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Modification Methylases; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Membrane Proteins; Mesothelioma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Pleural Neoplasms; T-Lymphocytes, Cytotoxic; Valproic Acid; Vorinostat

2011
Downregulation of MUC1 expression and its recognition by CD8⁺ T cells on the surface of malignant pleural mesothelioma cells treated with HDACi.
    European journal of immunology, 2012, Volume: 42, Issue:3

    Topics: Antigens, Neoplasm; Azacitidine; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Decitabine; Down-Regulation; Drug Therapy, Combination; Flow Cytometry; Histone Deacetylase Inhibitors; Humans; Kinetics; Membrane Proteins; Mesothelioma; Mucin-1; Real-Time Polymerase Chain Reaction; RNA; Statistics, Nonparametric; Valproic Acid

2012
Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2008, Volume: 3, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mesothelioma; Middle Aged; Polymerase Chain Reaction; Prognosis; Survival Rate

2008
Cancer testis antigens expression in mesothelioma: role of DNA methylation and bioimmunotherapeutic implications.
    British journal of cancer, 2002, Mar-18, Volume: 86, Issue:6

    Topics: Animals; Antigens, Neoplasm; Azacitidine; DNA Methylation; Female; Humans; Immunotherapy; Male; Melanoma-Specific Antigens; Membrane Proteins; Mesothelioma; Neoplasm Proteins; Proteins; Rabbits; Repressor Proteins; Testis

2002
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells.
    Oncogene, 2002, Jun-20, Volume: 21, Issue:27

    Topics: Alleles; Azacitidine; Cell Line, Transformed; Cell Transformation, Viral; Cocarcinogenesis; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation; Gene Silencing; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Mesothelioma; Neoplasm Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Simian virus 40; Tumor Suppressor Proteins

2002
Chemotherapy for malignant mesothelioma with adriamycin and continuous infusion of 5-azacytidine.
    Cancer treatment reports, 1978, Volume: 62, Issue:7

    Topics: Azacitidine; Doxorubicin; Drug Evaluation; Female; Humans; Infusions, Parenteral; Male; Mesothelioma; Middle Aged

1978
Diffuse pulmonary malignant mesothelioma: response to doxorubicin and 5-azacytidine.
    Cancer, 1978, Volume: 42, Issue:4

    Topics: Azacitidine; Doxorubicin; Drug Therapy, Combination; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Mesothelioma; Middle Aged; Remission, Spontaneous

1978