azacitidine and Innate Inflammatory Response

azacitidine has been researched along with Innate Inflammatory Response in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (7.14)29.6817
2010's21 (75.00)24.3611
2020's5 (17.86)2.80

Authors

AuthorsStudies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Fujimoto, M; Iwasaki, M; Kanda, J; Kataoka, A; Mizumoto, C; Nannya, Y; Ogawa, S; Oka, T; Sakurada, M; Takaori-Kondo, A; Yamamoto, Y; Yamashita, K1
He, S; Liang, B; Ming, X; Rong, J; Xiang, Y; Xu, X; Yang, G; Zhang, X; Zheng, F1
Chen, CM; Chen, LC; Kuo, ML; Lu, CH; Ma, J; Wu, CJ1
Kornicka-Grabowska, K; Marycz, K; Mularczyk, M; Siwinska, N; Weiss, C1
Aisa, Y; Akimoto, M; Ito, C; Nakazato, T; Nishiyama-Fujita, Y; Sakurai, A1
Blennerhassett, MG; Bonafiglia, QA; Hurlbut, DJ; Lourenssen, SR1
Cai, L; Li, Q; Mo, Z; Xu, Q; Zhan, M1
Bian, EB; Cheng, C; He, Y; Huang, C; Li, J; Ma, TT; Zhang, L1
Dornaus, S; Frietsch, JJ; Hochhaus, A; Kunert, C; La Rosée, P; Neumann, T; Sayer, HG; Schmidt, V; Scholl, S1
Atanackovic, D; Badbaran, A; Binder, TM; Fehse, B; Hildebrandt, Y; Kröger, N; Luetkens, T; Stübig, T1
Dawn, B; Elias, HK; Malik, AB; Rajasingh, J; Rajasingh, S; Simpson, AD; Sundivakkam, PK; Thangavel, J; Vogel, SM; Xuan, YT1
Barani, B; Dawn, B; Rajasingh, J; Rajasingh, S; Samanta, S; Thangavel, J; Xuan, YT1
Gorman, S; Hart, PH; McGonigle, TA; Ng, RL; Scott, NM1
Adès, L; Amoura, Z; Braun, T; Buchdaul, AL; Cathebras, P; Costedoat-Chalumeau, N; De Wazieres, B; Decaux, O; Denis, G; Dion, J; Fain, O; Falgarone, G; Fenaux, P; Gardin, C; Georgin-Lavialle, S; Gombert, B; Grignano, E; Hamidou, M; Kahn, JE; Launay, D; Lioger, B; Liozon, E; Lortholary, O; Madaule, S; Mathian, A; Mekinian, A; Montestruc, F; Morel, N; Nimubona, S; Omouri, M; Park, S; Piette, JC; Puéchal, X; Raffray, L; Rose, C; Rossignol, J; Schoindre, Y; Toussirot, E; Trouiller, S; Ziza, JM1
Inagaki, S; Kanbe, E; Sato, S; Tamai, Y; Tanaka, E; Yoshizawa, M1
Aouba, A; Arlet, JB; Berthier, S; Braun, T; Buchdahl, AL; Decaux, O; Denis, G; Fain, O; Fenaux, P; Fraison, JB; Gardin, C; Grignano, E; Kahn, JE; Leon, N; Liozon, E; Lortholary, O; Maigne, G; Mekinian, A; Omouri, M; Park, S; Rossignol, J1
Clarke, PAG; Davis, R; Kwabi-Addo, B; Mumuni, S; Wang, S1
Cao, Q; Shi, H; Wang, X; Xue, B; Yu, L1
Barat, C; Dental, C; Ouellet, M; Proust, A; Tremblay, MJ1
Ali, MW; Alqinyah, M; Cacan, E; Gao, M; Greer, SF; Hooks, SB; Maganti, N; Weng, HR; Yadav, R1
Fonte, E; Ghia, P; Muzio, M; Ntoufa, S; Papakonstantinou, N; Ranghetti, P; Scarfò, L; Stamatopoulos, K; Tocchetti, M; Veliz Rodriguez, T; Vilia, MG1
Cui, S; Eauclaire, SF; Lorent, K; Matthews, RP; Mugnier, M; Pack, M; Ross, MM; Russo, P; Zhang, Z1
Diesel, B; Kiemer, AK; Ripoche, N; Risch, RT; Tierling, S; Walter, J1
Gao, XP; Gomes, I; Kishore, R; Malik, AB; Rajasingh, J; Siddiqui, MR; Thangavel, J1
Dimmler, A; El-Rifai, W; Faller, G; Frischauf, M; Hartmann, A; Jung, A; Konturek, PC; Rau, TT; Rogler, A; Schneider-Stock, R; Sehnert, B; Voll, RE1
Bressler, L; Chen, YH; DeSimone, J; Dorn, L; Gavazova, S; Hillery, CA; Hoffman, R; Lavelle, D; Molokie, R; Saunthararajah, Y1
Cheung, J; Furuta, T; Gruenert, DC; Kai, H; Li, JD; Oba, M; Okiyoneda, T; Shuto, T; Suico, MA; Uehara, A; Xu, H1

Reviews

1 review(s) available for azacitidine and Innate Inflammatory Response

ArticleYear
Paraneoplastic inflammation in myelodysplastic syndrome or bone marrow failure: case series with focus on 5-azacytidine and literature review.
    European journal of haematology, 2014, Volume: 93, Issue:3

    Topics: Adult; Aged; Anemia, Aplastic; Antimetabolites, Antineoplastic; Autoimmunity; Azacitidine; Bone Marrow; Bone Marrow Diseases; Bone Marrow Failure Disorders; Diagnosis, Differential; Female; Hemoglobinuria, Paroxysmal; Humans; Inflammation; Male; Middle Aged; Myelodysplastic Syndromes; Paraneoplastic Syndromes; Treatment Outcome

2014

Trials

1 trial(s) available for azacitidine and Innate Inflammatory Response

ArticleYear
Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease.
    Blood, 2003, Dec-01, Volume: 102, Issue:12

    Topics: Adult; Anemia, Sickle Cell; Azacitidine; Biomarkers; Blood Coagulation; Bone Marrow; Cell Adhesion; Cell Differentiation; Decitabine; DNA Methylation; Endothelium, Vascular; Erythrocytes; Female; Fetal Hemoglobin; Hematopoiesis; Humans; Inflammation; Laminin; Male; Middle Aged; Thrombospondins; Vascular Diseases

2003

Other Studies

26 other study(ies) available for azacitidine and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Successful azacitidine therapy for myelodysplastic syndrome associated with VEXAS syndrome.
    International journal of hematology, 2023, Volume: 117, Issue:6

    Topics: Aged; Azacitidine; Enzyme Inhibitors; Exanthema; Fever; Humans; Inflammation; Male; Mutation; Myelodysplastic Syndromes

2023
Thioredoxin-interacting protein promotes activation and inflammation of monocytes with DNA demethylation in coronary artery disease.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:6

    Topics: 3' Untranslated Regions; Aged; Azacitidine; Biomarkers; Carrier Proteins; Case-Control Studies; Coronary Artery Disease; DNA Demethylation; Female; Foam Cells; Humans; Inflammation; Male; Middle Aged; Monocytes; RNA, Messenger; THP-1 Cells

2020
DNA methyltransferase inhibitor alleviates bleomycin-induced pulmonary inflammation.
    International immunopharmacology, 2020, Volume: 84

    Topics: Acute Lung Injury; Animals; Antibiotics, Antineoplastic; Azacitidine; Bleomycin; Bronchoalveolar Lavage Fluid; Cytokines; DNA Modification Methylases; Female; Inflammation; Leukocyte Count; Lung; Mice, Inbred C57BL

2020
Extracellular Microvesicles (MV's) Isolated from 5-Azacytidine-and-Resveratrol-Treated Cells Improve Viability and Ameliorate Endoplasmic Reticulum Stress in Metabolic Syndrome Derived Mesenchymal Stem Cells.
    Stem cell reviews and reports, 2020, Volume: 16, Issue:6

    Topics: Animals; Apoptosis; Autophagy; Azacitidine; Cell Survival; Cytokines; Endoplasmic Reticulum Stress; Extracellular Vesicles; Female; Horses; Inflammation; Male; Mesenchymal Stem Cells; Metabolic Syndrome; Oxidative Stress; Resveratrol

2020
The prognostic value of the Fibrinogen-Albumin Ratio Index in patients with myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes treated with azacitidine.
    Annals of hematology, 2021, Volume: 100, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Female; Fibrinogen; Follow-Up Studies; Humans; Inflammation; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Proportional Hazards Models; Retrospective Studies; ROC Curve; Serum Albumin, Human

2021
Epigenetic modification of intestinal smooth muscle cell phenotype during proliferation.
    American journal of physiology. Cell physiology, 2018, 11-01, Volume: 315, Issue:5

    Topics: Actins; Animals; Azacitidine; Cell Proliferation; Crohn Disease; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Histone Deacetylase 2; Histone Deacetylases; Humans; Hydroxamic Acids; Ileum; Inflammation; Intestinal Mucosa; Intestines; Muscle Contraction; Myocytes, Smooth Muscle; Rats

2018
The effect of DNA methylation on the miRNA expression pattern in lipopolysaccharide-induced inflammatory responses in human dental pulp cells.
    Molecular immunology, 2019, Volume: 111

    Topics: Azacitidine; Cells, Cultured; Cytokines; Dental Pulp; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Humans; Inflammation; Lipopolysaccharides; MicroRNAs; Promoter Regions, Genetic; RNA, Messenger

2019
SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages.
    Toxicology letters, 2014, Mar-21, Volume: 225, Issue:3

    Topics: Animals; Azacitidine; Blotting, Western; Cell Line; Cytokines; Decitabine; DNA Methylation; Epigenesis, Genetic; Inflammation; Macrophage Activation; Macrophages; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins

2014
5-azacytidine promotes an inhibitory T-cell phenotype and impairs immune mediated antileukemic activity.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Antimetabolites, Antineoplastic; Azacitidine; CD8-Positive T-Lymphocytes; Cell Lineage; HL-60 Cells; Humans; Inflammation; K562 Cells; L-Lactate Dehydrogenase; Leukemia; Male; Middle Aged; Phenotype; Stem Cell Transplantation; T-Lymphocytes, Regulatory; Th1 Cells; Transplantation, Homologous

2014
Combinatorial therapy with acetylation and methylation modifiers attenuates lung vascular hyperpermeability in endotoxemia-induced mouse inflammatory lung injury.
    The American journal of pathology, 2014, Volume: 184, Issue:8

    Topics: Acetylation; Acute Lung Injury; Animals; Azacitidine; Blotting, Western; Capillary Permeability; Cell Proliferation; Cell Survival; Chromatin Immunoprecipitation; Decitabine; Disease Models, Animal; Drug Therapy, Combination; Endothelial Cells; Endotoxemia; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Hydroxamic Acids; In Situ Nick-End Labeling; Inflammation; Lung; Male; Methylation; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction

2014
Epigenetic modifiers reduce inflammation and modulate macrophage phenotype during endotoxemia-induced acute lung injury.
    Journal of cell science, 2015, Aug-15, Volume: 128, Issue:16

    Topics: Acute Lung Injury; Animals; Azacitidine; Decitabine; Drug Combinations; Endotoxemia; Epigenesis, Genetic; Histone Deacetylases; Humans; Hydroxamic Acids; Inflammation; Lipopolysaccharides; Macrophages; Methyltransferases; Mice; Sepsis; Signal Transduction

2015
Reduced immune responses in chimeric mice engrafted with bone marrow cells from mice with airways inflammation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2015, Volume: 64, Issue:11

    Topics: Administration, Intranasal; Adoptive Transfer; Animals; Azacitidine; Bone Marrow Cells; Bronchoalveolar Lavage Fluid; Cell Count; Decitabine; Dendritic Cells; Disease Models, Animal; DNA Modification Methylases; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Immunoglobulin E; Immunoglobulin G; Inflammation; Lipopolysaccharides; Lymph Nodes; Mice, Inbred C57BL; Organic Chemicals; Ovalbumin; Radiation Chimera; Respiratory Hypersensitivity; Skin

2015
Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective study.
    Rheumatology (Oxford, England), 2016, Volume: 55, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Autoimmunity; Azacitidine; Drug Therapy, Combination; Female; Follow-Up Studies; France; Glucocorticoids; Humans; Inflammation; Leukemia, Myelomonocytic, Chronic; Male; Myelodysplastic Syndromes; Prognosis; Retrospective Studies

2016
[Unidentified Inflammatory Disease Induced by Azacitidine Therapy for Myelodysplastic Syndrome].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Fatal Outcome; Female; Humans; Inflammation; Interleukin-6; Myelodysplastic Syndromes

2015
Efficacy of Azacitidine in autoimmune and inflammatory disorders associated with myelodysplastic syndromes and chronic myelomonocytic leukemia.
    Leukemia research, 2016, Volume: 43

    Topics: Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azacitidine; Female; Humans; Inflammation; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Myelodysplastic Syndromes; Retrospective Studies

2016
Sex steroid-induced DNA methylation changes and inflammation response in prostate cancer.
    Cytokine, 2016, Volume: 86

    Topics: Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Chemokine CXCL5; Chemokines, CC; Cytokines; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Hydroxamic Acids; Inflammation; Interleukin-5; Male; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Neoplasms; Tissue Array Analysis; Tumor Cells, Cultured

2016
Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity.
    JCI insight, 2016, Nov-17, Volume: 1, Issue:19

    Topics: Animals; Azacitidine; Cytokines; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenesis, Genetic; Inflammation; Insulin Resistance; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; PPAR gamma; Promoter Regions, Genetic

2016
HIV-1 Latency-Reversing Agents Prostratin and Bryostatin-1 Induce Blood-Brain Barrier Disruption/Inflammation and Modulate Leukocyte Adhesion/Transmigration.
    Journal of immunology (Baltimore, Md. : 1950), 2017, 02-01, Volume: 198, Issue:3

    Topics: Acetamides; Azacitidine; Azepines; Blood-Brain Barrier; Bryostatins; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cells, Cultured; Chemokine CCL2; Cytokines; Decitabine; HIV-1; Humans; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Phorbol Esters; Quinazolines; Receptors, Cell Surface; Virus Latency

2017
Regulator of G Protein Signaling 10 (Rgs10) Expression Is Transcriptionally Silenced in Activated Microglia by Histone Deacetylase Activity.
    Molecular pharmacology, 2017, Volume: 91, Issue:3

    Topics: Acetylation; Animals; Azacitidine; Cell Line; Chemokine CXCL2; Disease Models, Animal; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Inflammation; Lipopolysaccharides; Lysophospholipids; Methyltransferases; Mice, Inbred C57BL; Microglia; Promoter Regions, Genetic; Receptors, G-Protein-Coupled; RGS Proteins; RNA, Messenger; Signal Transduction; Sphingosine; Transcription, Genetic; Tumor Necrosis Factor-alpha

2017
The inhibitory receptor toll interleukin-1R 8 (TIR8/IL-1R8/SIGIRR) is downregulated in chronic lymphocytic leukemia.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Disease Models, Animal; DNA Methylation; Humans; Inflammation; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Receptors, Interleukin-1

2017
DNA hypomethylation causes bile duct defects in zebrafish and is a distinguishing feature of infantile biliary atresia.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:3

    Topics: Adenosylhomocysteinase; Animals; Azacitidine; Bile Ducts; Biliary Atresia; DNA Methylation; Epigenomics; Humans; Inflammation; Interferon-gamma; Zebrafish

2011
Inflammation-induced up-regulation of TLR2 expression in human endothelial cells is independent of differential methylation in the TLR2 promoter CpG island.
    Innate immunity, 2012, Volume: 18, Issue:1

    Topics: Azacitidine; Cell Line; CpG Islands; DNA Methylation; Endothelial Cells; Epigenesis, Genetic; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Immunity, Innate; Inflammation; Promoter Regions, Genetic; Sequence Analysis, DNA; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha

2012
Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Animals; Azacitidine; Bone Marrow Cells; Cell Differentiation; Decitabine; Endothelial Cells; Epigenesis, Genetic; Gene Expression Regulation; Heart; Hydroxamic Acids; Inflammation; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; Neovascularization, Physiologic; Pluripotent Stem Cells; Stem Cell Transplantation; Stem Cells; Ventricular Dysfunction, Left

2011
Methylation-dependent activation of CDX1 through NF-κB: a link from inflammation to intestinal metaplasia in the human stomach.
    The American journal of pathology, 2012, Volume: 181, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Base Sequence; Chromatin; Conserved Sequence; CpG Islands; DNA Methylation; Female; Gastric Mucosa; Gastritis; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Inflammation; Intestinal Mucosa; Intestines; Male; Metaplasia; Middle Aged; Molecular Sequence Data; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Stomach; Stomach Neoplasms; Tumor Necrosis Factor-alpha; Young Adult

2012
Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatory response toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:6

    Topics: Azacitidine; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; DNA Methylation; Endoplasmic Reticulum; Epithelial Cells; Gene Expression Regulation; Humans; Inflammation; Peptidoglycan; Promoter Regions, Genetic; Respiratory Mucosa; Staphylococcus aureus; Toll-Like Receptor 2; Up-Regulation

2006