azacitidine has been researched along with Glioma in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (8.33) | 18.2507 |
| 2000's | 15 (31.25) | 29.6817 |
| 2010's | 25 (52.08) | 24.3611 |
| 2020's | 4 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| da Costa Rosa, M; Riggins, GJ; Yamashita, AS | 1 |
| Furukawa, K; Higashimoto, K; Kaneko, K; Ohkawa, Y; Ohmi, Y; Soejima, H; Yamamoto, Y | 1 |
| Annereau, M; Bielle, F; Capelle, L; de Botton, S; Dehais, C; Delattre, JY; Federici, L; Hoang-Xuan, K; Idbaih, A; Laigle-Donadey, F; Lemare, F; Sanson, M; Touat, M; Willekens, C | 1 |
| Hartung, EE; Mukhtar, SZ; Niles, LP; Shah, SM | 1 |
| Jiang, Y; Jin, C; Li, M; Ouyang, Y; Tan, Z | 1 |
| Bian, E; Guo, Z; Li, G; Ma, CC; Wan, J; Zhao, B | 1 |
| Borodovsky, A; Chan, T; da Costa Rosa, M; Festuccia, WT; Riggins, GJ; Yamashita, AS | 1 |
| Bolyard, C; Chiocca, EA; Fernandez, S; Haseley, A; Kasai, K; Kaur, B; Lehman, A; Meisen, H; Mo, X; Okemoto, K; Wagner, B; Wehr, A | 1 |
| Baia, GS; Baylin, SB; Borodovsky, A; Chan, TA; Eberhart, CG; Fabius, AW; Gallia, GL; Riggins, GJ; Salmasi, V; Turcan, S; Weingart, JD | 1 |
| Borodovsky, A; Brennan, C; Chan, TA; Fabius, AW; Huse, J; Pedraza, A; Riggins, GJ; Turcan, S; Viale, A | 1 |
| Geng, P; Liu, K; Yao, J; Zhang, J; Zhou, B; Zhu, W; Zhu, Y | 1 |
| Bao, Z; Feng, Y; Guo, T; Jiang, C; Jiang, T; Li, M; Liu, Q; Sun, L; Wang, H; Yan, Z; Yang, X; Zhang, C; Zhang, Q | 1 |
| Bi, SQ; Fu, J; Lin, YD; Luo, B; Luo, GR; Shen, N; Xiao, SW; Xie, S; Xie, XX; Zhang, QM; Zhou, SF | 1 |
| Chen, C; Deng, Q; Dong, X; Jia, W; Nie, X; Xu, C; Xu, R; Zhang, M | 1 |
| Li, M; Sun, LG; Tian, XY; Zhang, L | 1 |
| Beckhove, P; Gal, Z; Grabe, N; Herold-Mende, C; Lahrmann, B; Lasitschka, F; Mock, A; Mossemann, J; Schmezer, P; Schmoch, T; Unterberg, A | 1 |
| Amankulor, N; Chan, T; Chang, Y; Choi, J; Deibert, C; Engh, J; Grandi, P; Kim, WJ; Kohanbash, G; Lotze, M; Okada, H; Park, Y; Pomerantz, A; Rao, A; Sette, P; Zhang, X | 1 |
| Lan, Q; Li, Z; Liu, H; Qu, M; Wang, Z; Xu, L; Yu, J; Zhang, S; Zhong, Q; Zhu, Q | 1 |
| Carosella, ED; Daunay, A; de Almeida, BS; Donadi, EA; Moreau, P; Poras, I; Simoes, RT; Tost, J; Yaghi, L | 1 |
| Barba, L; Bassoy, EY; Boehler, M; Calvo Tardón, M; Dietrich, PY; Jueliger, S; Marinari, E; Martinvalet, D; Pellegatta, S; Riccadonna, C; Taverna, P; Vuillefroy de Silly, R; Walker, PR; Yacoub Maroun, C | 1 |
| Hu, G; Hu, L; Lu, Y; Ma, J; Meng, W; Wang, J; Zhang, C | 1 |
| Bonazzi, VF; Hayward, NK; Irwin, D | 1 |
| Gu, Z; Horii, A; Inomata, K; Mitsui, H | 1 |
| Ito, M; Kondo, Y; Maeda, Y; Natsume, A; Oi, S; Saito, K; Shimato, S; Wakabayashi, T | 1 |
| Capper, D; Gaiser, T; Habel, A; Hartmann, C; Herold-Mende, C; Mueller, W; Siegelin, MD; von Deimling, A | 1 |
| Gong, F; Ji, SP; Li, AM; Tai, JL; Zhang, YP; Zheng, CQ | 1 |
| Elias, A; Korn, B; Lass, U; Mueller, W; Siegelin, MD; Steinmüller, A; von Deimling, A | 1 |
| Jiao, H; Kere, J; Nistér, M; Qu, M; Ren, ZP; Smits, A; Zhao, J | 1 |
| Hueng, DY; Jan, HJ; Lai, JH; Lee, CC; Lee, HM; Ma, HI; Shih, YL; Wei, HW | 1 |
| Ayala-Ortega, E; Dávalos-Salas, M; Furlan-Magaril, M; González-Buendía, E; Recillas-Targa, F; Valdes-Quezada, C | 1 |
| Chu, SH; Feng, DF; Jiang, PC; Li, ZQ; Ma, YB; Zhang, H; Zhu, ZA | 1 |
| Chu, SH; Feng, DF; Ma, YB; Qiu, JH; Zhang, H; Zhu, ZA | 1 |
| Dam, MA; Eskin, A; Kim, W; Konkankit, VV; Koya, RC; Liau, LM; Nelson, S; Prins, RM; Ribas, A | 1 |
| Alonso, MM; Aramburu, A; Bandrés, E; Cortes-Santiago, N; Diez-Valle, R; Fueyo, J; García-Foncillas, J; Gomez-Manzano, C; Idoate, MA; Jauregi, P; Lang, FF; Liu, D; Lopez de Munain, A; Manterola, L; Odero, MD; Rubio, A; Sampron, N; Tejada-Solís, S; Urquiza, L; Vicente, C | 1 |
| Geng, J; Luo, H; Pu, Y; Wu, X; Xu, W; Yang, Z; Zhou, Z | 1 |
| Ali-Osman, F; Dinh, DH; Foster, DC; Gujrati, M; Kisiel, W; Kondraganti, S; Konduri, SD; Lakka, SS; Olivero, WC; Rao, JS; Srivenugopal, KS; Yanamandra, N | 1 |
| Dallol, A; Eng, C; Hesson, L; Krex, D; Latif, F; Maher, ER | 1 |
| Benos, DJ; Bubien, JK; Fuller, CM; Gillespie, GY; Mapstone, TB; Markert, JM; Xia, J; Zhou, ZH | 1 |
| Longo, M; Nelson, PS; Schuster, JM | 1 |
| Horiguchi, K; Ishiuchi, S; Kurihara, H; Mori, M; Saito, N; Tomizawa, Y; Tosaka, M | 1 |
| Gu, J; Li, J; Lin, S; Lu, W; Wang, Y; Yu, J; Zhang, H; Zhu, J | 1 |
| Fahey, J; Field, L; Foltz, G; Frakes, A; Hood, L; Lee, H; Madan, A; Nelson, T; Ryken, TC; Ryu, GY; Sibenaller, Z; Vibhakar, R; Yoon, JG; Zander, K | 1 |
| Lea, R; Patel, R; Shervington, A; Shervington, L | 1 |
| Ito, M; Kawatsura, H; Kondo, Y; Kuzushima, K; Narita, Y; Natsume, A; Sekido, Y; Shimato, S; Tsujimura, K; Wakabayashi, T; Yoshida, J | 1 |
| Eyre, HJ; Selby, GB; Townsend, J; Upchurch, C | 1 |
| Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D | 1 |
| Berger, MS; Cavenee, WK; Costello, JF; Huang, HS | 1 |
| Brachet, P; Canova, C; Chevalier, G; Remy, S; Wion, D | 1 |
1 trial(s) available for azacitidine and Glioma
| Article | Year |
|---|---|
A phase II evaluation of fazarabine in high-grade gliomas: a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Azacitidine; Brain Neoplasms; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Southwestern United States; Treatment Failure | 1994 |
47 other study(ies) available for azacitidine and Glioma
| Article | Year |
|---|---|
Evaluation of a DNA demethylating agent in combination with all-trans retinoic acid for IDH1-mutant gliomas.
Topics: Animals; Azacitidine; Brain Neoplasms; DNA Methylation; Glioma; Humans; Isocitrate Dehydrogenase; Mice; Mutation; Tretinoin | 2022 |
Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells.
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Gangliosides; Gene Expression; Gene Expression Regulation, Neoplastic; Glioma; Humans; Promoter Regions, Genetic | 2023 |
5-Azacitidine in patients with IDH1/2-mutant recurrent glioma.
Topics: Adult; Aged; Azacitidine; Brain Neoplasms; Female; Glioma; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Mutation | 2020 |
5-Azacytidine upregulates melatonin MT
Topics: Animals; Azacitidine; Cell Line; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation, Neoplastic; Glioma; Histone Deacetylase Inhibitors; Hydroxamic Acids; Melatonin; Rats; Receptor, Melatonin, MT1; Receptors, Melatonin; RNA, Messenger; Transcriptional Activation; Valproic Acid | 2020 |
MiR-424 functions as a tumor suppressor in glioma cells and is down-regulated by DNA methylation.
Topics: Adult; Aged; Apoptosis; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Humans; MicroRNAs; Middle Aged; Oligodeoxyribonucleotides, Antisense; Time Factors; Transduction, Genetic | 2017 |
TGF-β-mediated repression of MST1 by DNMT1 promotes glioma malignancy.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Hepatocyte Growth Factor; Humans; Neoplasm Invasiveness; Proto-Oncogene Proteins; Transforming Growth Factor beta; Up-Regulation | 2017 |
Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Proliferation; Demethylation; DNA Methylation; Epigenesis, Genetic; Female; Glioma; Humans; Isocitrate Dehydrogenase; Mice; Mice, Nude; Mutation; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
DNA demethylating agents synergize with oncolytic HSV1 against malignant gliomas.
Topics: Animals; Azacitidine; Cell Line, Tumor; Cell Survival; CpG Islands; Disease Models, Animal; DNA Methylation; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Viral; Genetic Therapy; Genetic Vectors; Glioma; Herpesvirus 1, Human; Humans; Mice; Nestin; Oncolytic Virotherapy; Oncolytic Viruses; Promoter Regions, Genetic; Viral Proteins; Virus Replication; Xenograft Model Antitumor Assays | 2013 |
5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; DNA Methylation; Female; Glioma; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Male; Mice; Mice, Nude; Mutation; Xenograft Model Antitumor Assays | 2013 |
Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; Cell Differentiation; Cell Growth Processes; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Glioma; Heterografts; Humans; Isocitrate Dehydrogenase; Mice; Mice, SCID; Mutation | 2013 |
A new tumor suppressor LncRNA ADAMTS9-AS2 is regulated by DNMT1 and inhibits migration of glioma cells.
Topics: ADAM Proteins; ADAMTS9 Protein; Adult; Aged; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Invasiveness; RNA, Antisense; RNA, Long Noncoding; RNA, Small Interfering; Tumor Suppressor Proteins | 2014 |
Integrated analysis using methylation and gene expression microarrays reveals PDE4C as a prognostic biomarker in human glioma.
Topics: Adult; Aged; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cyclic Nucleotide Phosphodiesterases, Type 4; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Glioma; Humans; Male; Middle Aged; Promoter Regions, Genetic; Survival Analysis; Tumor Suppressor Protein p53 | 2014 |
MAGED4 expression in glioma and upregulation in glioma cell lines with 5-aza-2'-deoxycytidine treatment.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Glioma; Humans; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2014 |
Downregulation of HTATIP2 expression is associated with promoter methylation and poor prognosis in glioma.
Topics: Acetyltransferases; Antimetabolites, Antineoplastic; Azacitidine; Binding Sites; Brain Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; HEK293 Cells; Humans; Male; Middle Aged; Prognosis; Promoter Regions, Genetic; Sp1 Transcription Factor; Transcription Factors | 2015 |
Epigenetic Regulation of miR-129-2 Leads to Overexpression of PDGFRa and FoxP1 in Glioma Cells.
Topics: Adult; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Brain Neoplasms; Cell Proliferation; Chromatin Assembly and Disassembly; Decitabine; DNA Methylation; Epigenesis, Genetic; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Glioma; Humans; MicroRNAs; Real-Time Polymerase Chain Reaction; Receptor, Platelet-Derived Growth Factor alpha; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2015 |
Combined Treatment of ATRA with Epigenetic Drugs Increases Aggressiveness of Glioma Xenografts.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Epigenomics; Female; Glioma; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice, Inbred NOD; Mice, SCID; Tretinoin; Tumor Burden; Vorinostat; Xenograft Model Antitumor Assays | 2016 |
IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression.
Topics: Antineoplastic Agents; Azacitidine; Brain Neoplasms; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; GPI-Linked Proteins; Humans; Immunologic Surveillance; Intercellular Signaling Peptides and Proteins; Isocitrate Dehydrogenase; Killer Cells, Natural; Mutation; Real-Time Polymerase Chain Reaction; Transcriptome; Tumor Escape | 2016 |
Methylation-induced silencing of maspin contributes to the proliferation of human glioma cells.
Topics: Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Central Nervous System Neoplasms; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Humans; Promoter Regions, Genetic; Serpins | 2016 |
Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2.
Topics: 5' Untranslated Regions; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Exons; Genes, MHC Class I; Glioma; HLA-G Antigens; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immune System; Neoplasm Invasiveness; Polymorphism, Genetic; Promoter Regions, Genetic; Response Elements; Transcriptional Activation | 2016 |
Decitabine Treatment of Glioma-Initiating Cells Enhances Immune Recognition and Killing.
Topics: Animals; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; Fas Ligand Protein; fas Receptor; Gene Expression Regulation, Neoplastic; Genes, MHC Class I; Glioma; Humans; Intercellular Adhesion Molecule-1; Mice; Neoplastic Stem Cells; T-Lymphocytes, Cytotoxic; Up-Regulation; Xenograft Model Antitumor Assays | 2016 |
Methylation Status of the RIZ1 Gene Promoter in Human Glioma Tissues and Cell Lines.
Topics: Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Glioma; Histone-Lysine N-Methyltransferase; Humans; Male; Middle Aged; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors | 2017 |
Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma.
Topics: Azacitidine; Carrier Proteins; Cell Line, Tumor; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Expression Profiling; Gene Silencing; Genes, Tumor Suppressor; Glioma; Heat-Shock Proteins; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Melanoma; Membrane Proteins; Microfilament Proteins; Neuropeptides; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Phosphoprotein Phosphatases; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas.
Topics: Azacitidine; Base Sequence; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; DNA Methylation; DNA Mutational Analysis; Enzyme Inhibitors; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Humans; Hydroxamic Acids; Isoenzymes; Molecular Sequence Data; Promoter Regions, Genetic; Ubiquitin-Protein Ligases | 2008 |
Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells.
Topics: Antigens, Neoplasm; Azacitidine; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Gene Expression; Glioma; Histone Deacetylase Inhibitors; Histones; Humans; Immunotherapy; Membrane Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Valproic Acid | 2009 |
Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation.
Topics: AC133 Antigen; Antigens, CD; Azacitidine; Caspase 3; Caspase 7; Caspase 8; Cell Death; Cycloheximide; Decitabine; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Glioma; Glycoproteins; Humans; Peptides; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Protein Synthesis Inhibitors; RNA, Messenger; Stem Cells; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2009 |
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azacitidine; Brain Neoplasms; Cell Line, Tumor; CpG Islands; Dacarbazine; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Survival Rate; Temozolomide; Young Adult | 2009 |
Epigenetic silencing of death receptor 4 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in gliomas.
Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Silencing; Glioma; Humans; Promoter Regions, Genetic; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand | 2009 |
Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas.
Topics: Adolescent; Adult; Aged; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Child; Child, Preschool; Chromosomes, Human, Pair 19; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Genes, Tumor Suppressor; Glioma; Humans; Loss of Heterozygosity; Male; Middle Aged; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Young Adult | 2010 |
Osteopontin regulates human glioma cell invasiveness and tumor growth in mice.
Topics: Animals; Antineoplastic Agents; Azacitidine; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Decitabine; Electrophoresis, Polyacrylamide Gel; Glioma; Humans; Immunohistochemistry; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neoplasm Invasiveness; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; Vimentin; Xenograft Model Antitumor Assays | 2010 |
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter.
Topics: Azacitidine; Binding Sites; CCCTC-Binding Factor; Cell Line, Tumor; Decitabine; DNA Methylation; DNA, Neoplasm; Down-Regulation; Genes, Reporter; Genes, Retinoblastoma; Glioma; HeLa Cells; Humans; Hydroxamic Acids; K562 Cells; Mutation; Nucleic Acid Conformation; Promoter Regions, Genetic; Repressor Proteins; Sequence Analysis, DNA; Transgenes | 2011 |
Promoter methylation and downregulation of SLC22A18 are associated with the development and progression of human glioma.
Topics: Animals; Astrocytes; Azacitidine; Blotting, Western; Brain; Cell Adhesion; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; Humans; Mice; Neoplasm Grading; Neurons; Oligodendroglia; Organic Cation Transport Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Recurrence; RNA, Messenger | 2011 |
Effect of 5-Aza-2'-deoxycytidine on SLC22A18 in glioma U251 cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Cycle Checkpoints; Cell Line, Tumor; Decitabine; DNA Methylation; G1 Phase; Glioma; Humans; Organic Cation Transport Proteins; RNA, Messenger; S Phase | 2012 |
Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.
Topics: Antigens, Neoplasm; Azacitidine; Brain Neoplasms; Cell Death; Cell Line, Tumor; Coculture Techniques; Cytokines; Decitabine; Fas Ligand Protein; fas Receptor; Glioma; Histocompatibility Antigens Class I; Humans; Membrane Proteins; Molecular Targeted Therapy; Retroviridae; Signal Transduction; T-Lymphocytes; Transduction, Genetic; Up-Regulation | 2011 |
Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas.
Topics: Azacitidine; Blotting, Western; Cell Movement; Cell Proliferation; CpG Islands; DNA Methylation; DNA, Neoplasm; Epigenomics; Gene Amplification; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Humans; Neoplasm Invasiveness; Neoplastic Stem Cells; Phenotype; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; SOXB1 Transcription Factors; Tumor Cells, Cultured | 2011 |
Methylation mediated silencing of miR-23b expression and its role in glioma stem cells.
Topics: Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Decitabine; Down-Regulation; Epigenesis, Genetic; Gene Silencing; Glioma; Humans; Methylation; MicroRNAs; Neoplastic Stem Cells; Promoter Regions, Genetic; Temozolomide | 2012 |
Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
Topics: Azacitidine; Brain Neoplasms; Chromatin; Chromosomal Proteins, Non-Histone; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme Inhibitors; Gene Silencing; Glioblastoma; Glioma; Glycoproteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Methyl-CpG-Binding Protein 2; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins | 2003 |
Frequent epigenetic inactivation of the SLIT2 gene in gliomas.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Central Nervous System Neoplasms; CpG Islands; DNA Methylation; Extrachromosomal Inheritance; Gene Silencing; Genes, Tumor Suppressor; Glioma; Humans; Intercellular Signaling Peptides and Proteins; Loss of Heterozygosity; Middle Aged; Molecular Sequence Data; Nerve Tissue Proteins; Promoter Regions, Genetic; Tumor Cells, Cultured | 2003 |
Molecular cloning and characterization of human acid sensing ion channel (ASIC)2 gene promoter.
Topics: Acid Sensing Ion Channels; Azacitidine; Base Sequence; Binding Sites; Brain; Cloning, Molecular; CpG Islands; Decitabine; DNA; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Glioma; Humans; Luciferases; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA-Binding Proteins; RNA, Messenger; Sequence Analysis, DNA; Sodium Channels; Sp1 Transcription Factor; Transcription Factors; Transcription Initiation Site; Transfection; Tumor Cells, Cultured | 2003 |
Differential expression of bikunin (HAI-2/PB), a proposed mediator of glioma invasion, by demethylation treatment.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Membrane Glycoproteins; Methyltransferases; Neoplasm Invasiveness; Neoplasms; Oligonucleotide Array Sequence Analysis; Serine Proteinase Inhibitors; Trypsin Inhibitor, Kunitz Soybean; Tumor Cells, Cultured | 2003 |
Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors.
Topics: Azacitidine; Brain Neoplasms; Cell Line, Tumor; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; Genes, Tumor Suppressor; Glioma; Humans; Medulloblastoma; Neoplasm Proteins; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2003 |
Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma.
Topics: Adolescent; Adult; Antigens, Neoplasm; Astrocytoma; Azacitidine; Brain Neoplasms; Cadherins; Carcinoma, Hepatocellular; Child; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Genes, Tumor Suppressor; Glioma; Humans; Liver Neoplasms; Male; Melanoma-Specific Antigens; Middle Aged; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Sex Factors; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Proteins | 2004 |
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.
Topics: Azacitidine; Brain Neoplasms; Decitabine; DNA Methylation; Gene Expression; Gene Expression Profiling; Gene Silencing; Genes, Tumor Suppressor; Genome, Human; Glioma; Histones; Humans; Hydroxamic Acids; Nerve Tissue Proteins; Promoter Regions, Genetic | 2006 |
Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cellular Senescence; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Humans; Methyltransferases; Paclitaxel; RNA, Messenger; Telomerase | 2008 |
The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma.
Topics: Adoptive Transfer; Analysis of Variance; Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Asian People; Azacitidine; Blotting, Western; Brain Neoplasms; Chromosome Mapping; CpG Islands; Decitabine; DNA Methylation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioma; Histocompatibility Antigens Class I; Humans; Kaplan-Meier Estimate; Male; Membrane Proteins; Mice; Mice, Inbred NOD; Mice, SCID; Microarray Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Cytotoxic; Testis; Transplantation, Heterologous; Up-Regulation | 2008 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation.
Topics: Astrocytoma; Azacitidine; Base Sequence; Brain Chemistry; Brain Neoplasms; Carrier Proteins; Chromatin; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; Molecular Sequence Data; Neoplasm Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1996 |
Epigenetic control of programmed cell death: inhibition by 5-azacytidine of 1,25-dihydroxyvitamin D3-induced programmed cell death in C6.9 glioma cells.
Topics: Animals; Apoptosis; Azacitidine; Calcitriol; Decitabine; DNA Fragmentation; DNA Modification Methylases; Enzyme Inhibitors; Genes, myc; Glioma; Rats; Sphingosine; Tumor Cells, Cultured | 1998 |