azacitidine has been researched along with Experimental Neoplasms in 66 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 44 (66.67) | 18.7374 |
1990's | 3 (4.55) | 18.2507 |
2000's | 4 (6.06) | 29.6817 |
2010's | 15 (22.73) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Abbasi, MM; Beisler, JA; Driscoll, JS; Kelley, JA | 1 |
Liu, Y; Luo, F; Tu, L; Wang, Y; Zhang, N; Zhao, M | 1 |
Burkett, S; Cam, MC; Cunningham, T; Jailwala, P; Müller, F; Pastan, I; Stetler Stevenson, M; Stookey, S; Tai, CH; Wayne, AS | 1 |
He, TC; Liu, JX; Shao, ZW; Sheng, W; Shi, DY; Wang, BC; Wu, Q; Yang, SH; Zhang, ZC | 1 |
Matei, D; Mitra, AK; Mitra, S; Nephew, KP; Wang, Y; Zong, X | 1 |
Bai, XF; Ding, Y; Gao, L; Gao, XN; Jiang, MM; Li, JX; Li, YH; Lu, XC; Luo, XF; Mei, ZY; Qu, C; Shi, JL; Wang, J; Wang, LL; Wang, LX; Xu, YH; Yao, YS; Yu, L; Zhou, JH; Zhou, MH | 1 |
Allan, PW; Hollingshead, M; Maddry, JA; Maxuitenko, YY; Parker, WB; Sambandam, V; Thottassery, JV; Tiwari, K | 1 |
Ahn, JH; Choi, EN; Ju, W; Lyu, D; Park, AK; Sung, HY | 1 |
Asnaghi, L; Eberhart, CG; Enke, R; Handa, JT; Merbs, SL; Rajaii, F | 1 |
Ahn, JH; Ju, W; Sung, HY | 1 |
Ben-Shlomo, A; Cescato, R; Grotzky, A; Krause, T; Marincek, N; Meier, LP; Olariu, CI; Perren, A; Radojewski, P; Stettler, C; Taelman, VF; Walter, MA | 1 |
Gorantla, B; Knost, JA; Pulukuri, SM; Rao, JS | 1 |
Ali, IY; Gupta, C; Gupta, J; Tikoo, K | 1 |
Daurkin, I; Eruslanov, E; Kusmartsev, S; Vieweg, J | 1 |
Bigner, D; Croul, S; Eberhart, C; Grajkowska, W; Huang, A; Kongkham, PN; Li, M; Nakahara, Y; Northcott, PA; Ra, YS; Rutka, JT; Smith, C; Taylor, MD; Van Meter, T; Yan, H | 1 |
Bonfili, P; Di Staso, M; Festuccia, C; Gravina, GL; Jannini, EA; Marampon, F; Pestell, RG; Tombolini, V; Vitturini, A | 1 |
Bieblová, J; Bubeník, J; Indrová, M; Mikyšková, R; Polláková, V; Reiniš, M; Símová, J; Stěpánek, I | 1 |
Bardhan, K; Liu, K; McGaha, TL; Torres, CM; Yang, D; Zimmerman, M | 1 |
VESELY, J | 1 |
Bieblova, J; Bubenik, J; Hejnar, J; Indrova, M; Jandlova, T; Lubyova, B; Manning, J; Pribylova, H; Reinis, M; Simova, J | 1 |
Bernstein, ML; Chabot, GG; Hurtubise, A; Lemaire, M; Momparler, LF; Momparler, RL; Raynal, NJ | 1 |
Chiang, GH; Lu, LJ; Randerath, K | 1 |
Budĕsínský, M; Cihák, A; Hanna, NB; Pískala, A; Veselý, J | 1 |
Anisowicz, A; Gadi, IK; Harrison, JJ; Raffeld, M; Sager, R | 1 |
Frost, P; Kerbel, RS; Liteplo, RG | 1 |
Forchhammer, J; Olsson, L | 1 |
Gadi, IK; Harrison, JJ; Sager, R | 1 |
Carr, BI; Reilly, JG; Riggs, A; Smith, SS; Winberg, C | 1 |
Furusako, S; Kawashima, K; Mori, M; Namba, M; Usuki, H | 1 |
Prasanna, P; Samid, D; Shack, S; Wilson, VL | 1 |
Borsos, T; Ohanian, SH; Segerling, M | 3 |
Pitot, HC; Weiss, JW | 3 |
Billmire, DF; Keefer, RC; MacNamara, DJ; Schumm, DE; Webb, TE | 1 |
Altanerová, V | 1 |
Muggia, FM; Slavik, M; Von Hoff, DD | 1 |
Cihák, A; Rada, B | 1 |
Carter, SK; Slavik, M | 1 |
Greenberg, N; Hurtubise, PE; Schumm, DE; Webb, TE | 1 |
Goodman, J; Momparler, RL | 1 |
Grotzinger, K; McGuire, W; Young, R | 1 |
Abraham, D; Behrens, M; Plagemann, PG | 1 |
Bellet, RE; Berd, D; Danna, V; Mastrangelo, MJ | 1 |
Hustad, CM; Jones, PA | 1 |
Geber, E; Lehmacher, W; Schmahl, W | 1 |
Alvarez, E; Frost, P; Kerbel, RS; Liteplo, RG | 1 |
Breitman, TR; Cooney, DA; Dalal, M; del Campo, AA; Driscoll, JS; Johns, DG; Plowman, J; Schuller, HM; Vistica, DT | 1 |
Jones, PA; Kautiainen, TL | 1 |
Frost, P; Kerbel, RS; Liteplo, R | 1 |
Collins, JL; Lin, Y; Patek, PQ | 1 |
Matthews, AM; Shay, JW; Walker, C | 1 |
Asmeron, Y; Carr, BI; Rahbar, S; Riggs, A; Winberg, CD | 1 |
Fishman, PH; Kassis, S; Sullivan, M | 1 |
Collins, JL; Vanderslice, WE | 1 |
Babiss, LE; Fisher, PB; Zimmer, SG | 1 |
Martin, DW; Owen, NT | 1 |
Carter, SK | 1 |
Altaner, C; Altanerová, V | 1 |
Cihák, A; Veselỳ, J | 1 |
Keefer, RC; Morris, HP; Webb, TE | 1 |
Cihák, A; Pitot, HC; Weiss, JW | 2 |
Cihák, A | 1 |
4 review(s) available for azacitidine and Experimental Neoplasms
Article | Year |
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5-Azacytidine. A new anticancer drug with effectiveness in acute myelogenous leukemia.
Topics: Animals; Azacitidine; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Europe; Female; Humans; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Liver; Nausea; Neoplasms, Experimental; Neuromuscular Diseases; RNA, Messenger; United States; Vomiting | 1976 |
Investigational drugs under study by the United States National Cancer Institute.
Topics: Acrylates; Alkylating Agents; Ancitabine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Chemical Phenomena; Chemistry; Chromomycins; Cisplatin; DNA, Neoplasm; Drug Evaluation, Preclinical; Etoposide; Humans; Ifosfamide; Leukemia L1210; Mice; Mitosis; National Institutes of Health (U.S.); Neoplasms; Neoplasms, Experimental; Razoxane; Tegafur; Teniposide; United States | 1976 |
Resistance of mammalian tumour cells toward pyrimidine analogues. A review.
Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line; Cricetinae; Cytarabine; Deoxycytidine; Drug Resistance; Fluorouracil; Genetic Code; Leukemia, Experimental; Leukemia, Lymphoid; Mast-Cell Sarcoma; Mice; Mutation; Neoplasms, Experimental; Oncogenic Viruses; Phosphotransferases; Pyrimidines; Sarcoma, Experimental; Selection, Genetic; Thymidine Kinase; Uracil; Virus Replication | 1973 |
Effects of 5-azacytidine on hepatic polyribosomes and maturation of ribosomal RNA.
Topics: Animals; Azacitidine; Humans; Liver; Neoplasms, Experimental; Nucleic Acid Precursors; Polyribosomes; Rats; RNA, Messenger; RNA, Ribosomal | 1974 |
62 other study(ies) available for azacitidine and Experimental Neoplasms
Article | Year |
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Synthesis and antitumor activity of dihydro-5-azacytidine, a hydrolytically stable analogue of 5-azacytidine.
Topics: Animals; Antineoplastic Agents; Azacitidine; Hydrolysis; Leukemia L1210; Leukemia, Experimental; Melanoma; Mice; Neoplasms, Experimental | 1977 |
Decitabine reverses TGF-β1-induced epithelial-mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Survival; Decitabine; Epithelial-Mesenchymal Transition; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Neoplasms, Experimental; Transforming Growth Factor beta1; Tumor Cells, Cultured; Zinc Finger E-box-Binding Homeobox 1 | 2017 |
5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox.
Topics: Animals; Antineoplastic Agents; Azacitidine; Bacterial Toxins; Bone Marrow; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Exotoxins; Humans; Leukemia; Mice; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 2018 |
Epigenetic silencing of SFRP5 promotes the metastasis and invasion of chondrosarcoma by expression inhibition and Wnt signaling pathway activation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cells, Cultured; Chondrosarcoma; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epigenesis, Genetic; Eye Proteins; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Structure-Activity Relationship; Wnt Signaling Pathway | 2018 |
IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Azacitidine; Cell Line, Tumor; Cytokines; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Drug Therapy; Epigenomics; Female; Humans; Immunotherapy; Interleukin-6; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neoplastic Stem Cells; Ovarian Neoplasms; Platinum; Retinal Dehydrogenase; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment; Up-Regulation | 2018 |
Low dose decitabine treatment induces CD80 expression in cancer cells and stimulates tumor specific cytotoxic T lymphocyte responses.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; B7-1 Antigen; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Interleukin-2; K562 Cells; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Tumor Burden; U937 Cells | 2013 |
Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine.
Topics: Animals; Azacitidine; Blotting, Western; Cell Proliferation; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Female; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Real-Time Polymerase Chain Reaction; Thionucleosides; Tumor Cells, Cultured | 2014 |
Aberrant hypomethylation-mediated AGR2 overexpression induces an aggressive phenotype in ovarian cancer cells.
Topics: Animals; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mucoproteins; Neoplasm Metastasis; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Oncogene Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Proteins | 2014 |
The demethylating agent 5-Aza reduces the growth, invasiveness, and clonogenicity of uveal and cutaneous melanoma.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colony-Forming Units Assay; Decitabine; DNA Modification Methylases; DNA, Neoplasm; Humans; Melanoma; Melanoma, Cutaneous Malignant; Mice; Neoplasms, Experimental; Skin Neoplasms; Uveal Neoplasms | 2014 |
DNA hypomethylation-mediated overexpression of carbonic anhydrase 9 induces an aggressive phenotype in ovarian cancer cells.
Topics: Animals; Azacitidine; Carbonic Anhydrases; Carcinoma, Ovarian Epithelial; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Phenotype; Promoter Regions, Genetic; RNA, Messenger | 2014 |
Upregulation of Key Molecules for Targeted Imaging and Therapy.
Topics: Animals; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasms, Experimental; Organometallic Compounds; Pathology, Molecular; Positron-Emission Tomography; Receptors, Somatostatin; Reproducibility of Results; Sensitivity and Specificity; Up-Regulation | 2016 |
Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer.
Topics: Acetylation; Animals; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin; Cystatin M; Decitabine; Disease Progression; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasms, Experimental; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transplantation, Heterologous | 2009 |
5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blood Urea Nitrogen; Blotting, Western; Breast Neoplasms; Cell Nucleus; Cisplatin; Colonic Neoplasms; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Synergism; Drug Therapy, Combination; Female; Histones; Kidney Diseases; Male; Mammary Neoplasms, Experimental; Metallothionein; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley | 2009 |
Generation of antigen-presenting cells from tumor-infiltrated CD11b myeloid cells with DNA demethylating agent 5-aza-2'-deoxycytidine.
Topics: Animals; Antigen-Presenting Cells; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cancer Vaccines; CD11b Antigen; Cell Differentiation; Cell Separation; Cytokines; Decitabine; Female; Flow Cytometry; Immunotherapy; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid Cells; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.
Topics: Adult; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cerebellar Neoplasms; CpG Islands; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Loss of Heterozygosity; Medulloblastoma; Mice; Mice, Nude; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2010 |
5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Humans; Male; Mice; Mice, Nude; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Tosyl Compounds | 2010 |
Immunotherapy augments the effect of 5-azacytidine on HPV16-associated tumours with different MHC class I-expression status.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; DNA Primers; Enzyme-Linked Immunosorbent Assay; Histocompatibility Antigens Class I; Human papillomavirus 16; Immunotherapy; Male; Methylation; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Real-Time Polymerase Chain Reaction | 2011 |
Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo.
Topics: Adaptor Proteins, Signal Transducing; Adoptive Transfer; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; bcl-X Protein; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colonic Neoplasms; Decitabine; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Membrane Proteins; Mice; Mitochondrial Proteins; Neoplasm Metastasis; Neoplasms, Experimental; Proto-Oncogene Proteins; Tumor Escape; Vorinostat | 2012 |
THE EFFECT OF 6-AZAURIDINE AND 6-AZACYTIDINE ON THE INTRACELLULAR SYNTHESIS OF RNA IN FOWL LEUKEMIC AND NORMAL MYELOBLASTS IN VITRO.
Topics: Animals; Antimetabolites; Autoradiography; Azacitidine; Azauridine; Bone Marrow Examination; Cytoplasm; Granulocyte Precursor Cells; In Vitro Techniques; Leukemia; Leukemia, Experimental; Neoplasms, Experimental; Nucleosides; Poultry; Research; RNA; RNA, Neoplasm | 1964 |
Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours.
Topics: Animals; Antigen Presentation; Apoptosis; Azacitidine; Enzyme Inhibitors; Epigenesis, Genetic; Genes, MHC Class I; Histones; Human papillomavirus 16; Humans; Hydroxamic Acids; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Papillomavirus Infections; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Up-Regulation | 2008 |
Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor Proteins; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Administration Schedule; Epigenesis, Genetic; Genomic Imprinting; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasms, Experimental; Tumor Stem Cell Assay | 2008 |
Effects of 5-azacytidine on transfer RNA modification: comparative study on normal and malignant tissues.
Topics: Animals; Azacitidine; Cytidine; Mice; Neoplasms, Experimental; Rats; RNA, Transfer; tRNA Methyltransferases | 1980 |
Synthesis and biological activity of 2'-deoxy-6-methyl-5-azacytidine and its alpha-D-anomer.
Topics: Animals; Azacitidine; Drug Evaluation, Preclinical; Escherichia coli; Indicators and Reagents; Neoplasms, Experimental | 1981 |
Azacytidine-induced tumorigenesis of CHEF/18 cells: correlated DNA methylation and chromosome changes.
Topics: Adipose Tissue; Animals; Azacitidine; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cricetinae; DNA, Neoplasm; Karyotyping; Methylation; Mice; Mice, Nude; Neoplasms, Experimental; Trisomy | 1983 |
5-azacytidine induction of thymidine kinase in a spontaneously enzyme-deficient murine tumor line.
Topics: Animals; Azacitidine; Cell Division; Cell Line; DNA, Neoplasm; Enzyme Induction; Methylation; Mice; Neoplasms, Experimental; Thymidine Kinase | 1984 |
Induction of the metastatic phenotype in a mouse tumor model by 5-azacytidine, and characterization of an antigen associated with metastatic activity.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Azacitidine; DNA, Neoplasm; Methylation; Mice; Neoplasm Metastasis; Neoplasms, Experimental | 1984 |
Genetic analysis of tumorigenesis: XVI. Chromosome changes in azacytidine- and insulin-induced tumorigenesis.
Topics: Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Cricetinae; Cricetulus; Embryo, Mammalian; Insulin; Karyotyping; Neoplasms, Experimental | 1984 |
The tumorigenicity of 5-azacytidine in the male Fischer rat.
Topics: Animals; Azacitidine; DNA; Kidney Neoplasms; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphatic Diseases; Male; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Skin Neoplasms; Testicular Neoplasms | 1984 |
Human fibroblasts (KMST-6/RAS line) transformed with 60Co gamma-rays and c-Ha-ras oncogene constitutively produce a large amount of human granulocyte-colony stimulating factor (G-CSF).
Topics: Animals; Azacitidine; Butyrates; Cell Line; Cell Transformation, Neoplastic; Cobalt Radioisotopes; Dexamethasone; Fibroblasts; Gamma Rays; Genes, ras; Granulocyte Colony-Stimulating Factor; Humans; Mice; Mice, Nude; Neoplasms, Experimental | 1994 |
Phenylacetate in chemoprevention: in vitro and in vivo suppression of 5-aza-2'-deoxycytidine-induced carcinogenesis.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Azacitidine; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Chemoprevention; Clone Cells; Collagen; Decitabine; DNA Methylation; Drug Combinations; Female; Genes, ras; Laminin; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasms, Experimental; Phenylacetates; Proteoglycans | 1995 |
Chemotherapeutic drugs increase killing of tumor cells by antibody and complement.
Topics: Animals; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cyclophosphamide; Cytarabine; Fluorouracil; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Nitrosamines; Vincristine | 1975 |
Effects of 5-azacytidine on nucleolar RNA and the preribosomal particles in Novikoff hepatoma cells.
Topics: Animals; Azacitidine; Carcinoma, Hepatocellular; Cell Nucleolus; Cells, Cultured; Guanosine Triphosphate; Liver Neoplasms; Neoplasms, Experimental; Rats; Ribosomes; RNA, Neoplasm; RNA, Ribosomal | 1975 |
Early temporal changes in the uridine kinase isozyme profile of the Novikoff hepatoma in response to 5-azacytidine treatment.
Topics: Aging; Animals; Azacitidine; Carcinoma, Hepatocellular; DNA Replication; Dose-Response Relationship, Drug; Drug Resistance; Female; Isoenzymes; Liver Neoplasms; Neoplasms, Experimental; Phosphotransferases; Rats; Thymidine; Time Factors; Tritium; Uridine Kinase | 1975 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Effect of metabolic inhibitors on the ability of tumor cells to express antigen and bind complement components C4 and C3.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Binding Sites, Antibody; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Complement C3; Complement C4; Complement System Proteins; Dactinomycin; Doxorubicin; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Puromycin | 1975 |
Transformation of BHK 21/13 cells by chemical carcinogens and mutagens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azacitidine; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Methylcholanthrene; Mutagens; Neoplasms, Experimental; Retroviridae | 1975 |
Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review).
Topics: Animals; Azacitidine; Azauridine; Molecular Weight; Neoplasms, Experimental; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Species Specificity; Uridine; Uridine Kinase; Virus Diseases | 1976 |
Uridine kinase activities in normal and neoplastic lymphoid cells.
Topics: Animals; Azacitidine; B-Lymphocytes; Carcinoma, Hepatocellular; Cats; Enzyme Induction; Humans; Isoenzymes; Leukemia, Experimental; Leukemia, Lymphoid; Liver Neoplasms; Lymphocyte Activation; Lymphocytes; Lymphoma, Non-Hodgkin; Male; Mast-Cell Sarcoma; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Phosphotransferases; Rats; T-Lymphocytes; Uridine Kinase | 1977 |
In vitro cytotoxic and biochemical effects of 5-aza-2'-deoxycytidine.
Topics: Azacitidine; Cell Division; Cell Survival; Cells, Cultured; Cytidine; Deoxycytidine; DNA, Neoplasm; Fibrosarcoma; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm | 1977 |
Alterations in [3H]thymidine incorporation into DNA and [3H]uridine incorporation into RNA induced by 5-azacytidine in vivo.
Topics: Animals; Ascites; Azacitidine; Bone Marrow; DNA; Female; Intestinal Mucosa; Mice; Mice, Inbred Strains; Neoplasms, Experimental; RNA; Thymidine; Time Factors; Uridine | 1978 |
Metabolism and cytotoxicity of 5-azacytidine in cultured Novikoff rat hepatoma and P388 mouse leukemia cells and their enhancement by preincubation with pyrazofurin.
Topics: Amides; Animals; Antibiotics, Antineoplastic; Azacitidine; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Cytidine; DNA, Neoplasm; Drug Synergism; Leukemia, Experimental; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Phosphates; Pyrazoles; Ribonucleosides; Ribose; RNA, Neoplasm; Uridine | 1978 |
Evaluation of a "nude" mouse-human tumor panel as a predictive secondary screen for cancer chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carmustine; Dacarbazine; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Female; Humans; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental | 1979 |
Effect of myogenic determination on tumorigenicity of chemically transformed 10T1/2 cells.
Topics: Animals; Azacitidine; Blotting, Northern; Cell Differentiation; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA-Binding Proteins; Fluorescent Antibody Technique; Genetic Vectors; Methylcholanthrene; Mice; Muscle Proteins; Muscles; MyoD Protein; Myosins; Neoplasms, Experimental; RNA, Neoplasm; Transfection | 1991 |
Diaplacental carcinogenic effects of 5-azacytidine in NMRI-mice.
Topics: Animals; Azacitidine; Fetus; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma, Experimental; Soft Tissue Neoplasms | 1985 |
Induction of thymidine kinase activity in a spontaneously enzyme-deficient murine tumor cell line by exposure in vivo to the DNA-hypomethylating agent 5-aza-2'-deoxycytidine: implications for mechanisms of tumor progression.
Topics: Animals; Azacitidine; Cell Line; Decitabine; DNA; Enzyme Induction; Male; Methylation; Mice; Mice, Inbred DBA; Mutation; Neoplasms, Experimental; Thymidine Kinase | 1985 |
Arabinofuranosyl-5-azacytosine: antitumor and cytotoxic properties.
Topics: Animals; Azacitidine; Cell Cycle; Cell Differentiation; Cell Survival; Cells, Cultured; Humans; Mice; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Vidarabine | 1986 |
DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cattle; Cells, Cultured; Cricetinae; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Mesocricetus; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats | 1986 |
On the possible contribution of DNA hypomethylation to the induction of high frequency and heritable drug-induced alterations in the malignant phenotype.
Topics: Alkylating Agents; Animals; Azacitidine; Cell Line; DNA, Neoplasm; Gene Amplification; Humans; Methylation; Mice; Mutagens; Mutation; Neoplasms; Neoplasms, Experimental; Phenotype; Thymidine Kinase | 1986 |
Dissociation of contact-noninhibition in vitro and tumorigenicity in vivo.
Topics: Animals; Azacitidine; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; Contact Inhibition; Furans; Mice; Neoplasms, Experimental | 1986 |
Suppression of tumorigenicity mediated by 5-azacytidine and associated with increased chromosome number.
Topics: Animals; Azacitidine; Cell Line; Chromosomes; DNA, Neoplasm; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental | 1987 |
Carcinogenicity and haemoglobin synthesis induction by cytidine analogues.
Topics: Animals; Azacitidine; Cell Survival; Dose-Response Relationship, Drug; Female; Hemoglobins; Leydig Cell Tumor; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Rats; Rats, Inbred F344; Sheep; Testicular Neoplasms | 1988 |
Modulation of the beta-adrenergic receptor-coupled adenylate cyclase by chemical inducers of differentiation: effects on beta receptors and the inhibitory regulatory protein Gi.
Topics: Acetamides; Adenylyl Cyclases; Azacitidine; Butyrates; Butyric Acid; Cell Differentiation; Cells, Cultured; Enzyme Induction; GTP-Binding Proteins; HeLa Cells; Humans; Neoplasms, Experimental; Puromycin; Puromycin Aminonucleoside; Receptors, Adrenergic, beta | 1988 |
Anti-tumor surveillance of non-contact-inhibited transformed cell lines.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antigens, Neoplasm; Azacitidine; Cell Line, Transformed; Cell Transformation, Neoplastic; Histocompatibility Antigens; Immunity, Cellular; Immunologic Surveillance; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Phenotype | 1988 |
Reversibility of progression of the transformed phenotype in Ad5-transformed rat embryo cells.
Topics: Adenoviruses, Human; Animals; Azacitidine; Cell Division; Cell Transformation, Viral; Cells, Cultured; DNA, Neoplasm; DNA, Viral; Gene Expression Regulation; Genes, Viral; Methylation; Mice; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Transcription, Genetic | 1985 |
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; Feedback; Formates; Glycine; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Purines; Rats; Ribonucleotides; Ribose; Tetrahydrofolates; Tritium | 1972 |
New drugs on the horizon in bronchogenic carcinoma.
Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Bleomycin; Carcinoma, Bronchogenic; Carmustine; Cyclic P-Oxides; Cyclophosphamide; Dimethylamines; Doxorubicin; Ethylamines; Evaluation Studies as Topic; Humans; Ketones; Lung Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Organophosphorus Compounds; Oxazines; Piperazines; Platinum; Triazines | 1972 |
Characterization of chicken sarcoma viruses induced with chemical carcinogens and mutagens in transformed hamster cells.
Topics: Alpharetrovirus; Animals; Azacitidine; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Cricetinae; DNA Nucleotidyltransferases; Genetic Code; Methylcholanthrene; Mutation; Neoplasms, Experimental; Quinolines; RNA, Viral | 1972 |
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells.
Topics: Animals; Azacitidine; Azaguanine; Carcinoma, Hepatocellular; Cells, Cultured; Cytidine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Guanosine; Isotope Labeling; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1974 |
5-azacytidine-modified patterns of uridine kinase activities in normal and neoplastic tissues.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Enzyme Induction; Liver; Liver Neoplasms; Male; Mice; Neoplasms, Experimental; Phosphotransferases; Rats; Time Factors | 1974 |
Characterization of polyribosomes and maturation of ribosomal RNA in hepatoma cells treated with 5-azacytidine.
Topics: Animals; Azacitidine; Carcinoma, Hepatocellular; Cell Fractionation; Cells, Cultured; Cytoplasm; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Polyribosomes; Rats; RNA, Ribosomal; Time Factors; Tritium | 1974 |
Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.
Topics: Animals; Azacitidine; Azaguanine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Transcription, Genetic; Tritium; Uridine | 1974 |
Biological effects of 5-azacytidine in eukaryotes.
Topics: Animals; Azacitidine; DNA; DNA, Bacterial; DNA, Viral; Drug Resistance; Embryo, Mammalian; Enzyme Induction; Gastric Juice; Humans; Leukemia, Lymphoid; Liver; Liver Regeneration; Neoplasms; Neoplasms, Experimental; Polyamines; Polyribosomes; Protein Biosynthesis; RNA; Spleen; Tyrosine Transaminase; Uridine Kinase | 1974 |