azacitidine and Experimental Neoplasms

azacitidine has been researched along with Experimental Neoplasms in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199044 (66.67)18.7374
1990's3 (4.55)18.2507
2000's4 (6.06)29.6817
2010's15 (22.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abbasi, MM; Beisler, JA; Driscoll, JS; Kelley, JA1
Liu, Y; Luo, F; Tu, L; Wang, Y; Zhang, N; Zhao, M1
Burkett, S; Cam, MC; Cunningham, T; Jailwala, P; Müller, F; Pastan, I; Stetler Stevenson, M; Stookey, S; Tai, CH; Wayne, AS1
He, TC; Liu, JX; Shao, ZW; Sheng, W; Shi, DY; Wang, BC; Wu, Q; Yang, SH; Zhang, ZC1
Matei, D; Mitra, AK; Mitra, S; Nephew, KP; Wang, Y; Zong, X1
Bai, XF; Ding, Y; Gao, L; Gao, XN; Jiang, MM; Li, JX; Li, YH; Lu, XC; Luo, XF; Mei, ZY; Qu, C; Shi, JL; Wang, J; Wang, LL; Wang, LX; Xu, YH; Yao, YS; Yu, L; Zhou, JH; Zhou, MH1
Allan, PW; Hollingshead, M; Maddry, JA; Maxuitenko, YY; Parker, WB; Sambandam, V; Thottassery, JV; Tiwari, K1
Ahn, JH; Choi, EN; Ju, W; Lyu, D; Park, AK; Sung, HY1
Asnaghi, L; Eberhart, CG; Enke, R; Handa, JT; Merbs, SL; Rajaii, F1
Ahn, JH; Ju, W; Sung, HY1
Ben-Shlomo, A; Cescato, R; Grotzky, A; Krause, T; Marincek, N; Meier, LP; Olariu, CI; Perren, A; Radojewski, P; Stettler, C; Taelman, VF; Walter, MA1
Gorantla, B; Knost, JA; Pulukuri, SM; Rao, JS1
Ali, IY; Gupta, C; Gupta, J; Tikoo, K1
Daurkin, I; Eruslanov, E; Kusmartsev, S; Vieweg, J1
Bigner, D; Croul, S; Eberhart, C; Grajkowska, W; Huang, A; Kongkham, PN; Li, M; Nakahara, Y; Northcott, PA; Ra, YS; Rutka, JT; Smith, C; Taylor, MD; Van Meter, T; Yan, H1
Bonfili, P; Di Staso, M; Festuccia, C; Gravina, GL; Jannini, EA; Marampon, F; Pestell, RG; Tombolini, V; Vitturini, A1
Bieblová, J; Bubeník, J; Indrová, M; Mikyšková, R; Polláková, V; Reiniš, M; Símová, J; Stěpánek, I1
Bardhan, K; Liu, K; McGaha, TL; Torres, CM; Yang, D; Zimmerman, M1
VESELY, J1
Bieblova, J; Bubenik, J; Hejnar, J; Indrova, M; Jandlova, T; Lubyova, B; Manning, J; Pribylova, H; Reinis, M; Simova, J1
Bernstein, ML; Chabot, GG; Hurtubise, A; Lemaire, M; Momparler, LF; Momparler, RL; Raynal, NJ1
Chiang, GH; Lu, LJ; Randerath, K1
Budĕsínský, M; Cihák, A; Hanna, NB; Pískala, A; Veselý, J1
Anisowicz, A; Gadi, IK; Harrison, JJ; Raffeld, M; Sager, R1
Frost, P; Kerbel, RS; Liteplo, RG1
Forchhammer, J; Olsson, L1
Gadi, IK; Harrison, JJ; Sager, R1
Carr, BI; Reilly, JG; Riggs, A; Smith, SS; Winberg, C1
Furusako, S; Kawashima, K; Mori, M; Namba, M; Usuki, H1
Prasanna, P; Samid, D; Shack, S; Wilson, VL1
Borsos, T; Ohanian, SH; Segerling, M3
Pitot, HC; Weiss, JW3
Billmire, DF; Keefer, RC; MacNamara, DJ; Schumm, DE; Webb, TE1
Altanerová, V1
Muggia, FM; Slavik, M; Von Hoff, DD1
Cihák, A; Rada, B1
Carter, SK; Slavik, M1
Greenberg, N; Hurtubise, PE; Schumm, DE; Webb, TE1
Goodman, J; Momparler, RL1
Grotzinger, K; McGuire, W; Young, R1
Abraham, D; Behrens, M; Plagemann, PG1
Bellet, RE; Berd, D; Danna, V; Mastrangelo, MJ1
Hustad, CM; Jones, PA1
Geber, E; Lehmacher, W; Schmahl, W1
Alvarez, E; Frost, P; Kerbel, RS; Liteplo, RG1
Breitman, TR; Cooney, DA; Dalal, M; del Campo, AA; Driscoll, JS; Johns, DG; Plowman, J; Schuller, HM; Vistica, DT1
Jones, PA; Kautiainen, TL1
Frost, P; Kerbel, RS; Liteplo, R1
Collins, JL; Lin, Y; Patek, PQ1
Matthews, AM; Shay, JW; Walker, C1
Asmeron, Y; Carr, BI; Rahbar, S; Riggs, A; Winberg, CD1
Fishman, PH; Kassis, S; Sullivan, M1
Collins, JL; Vanderslice, WE1
Babiss, LE; Fisher, PB; Zimmer, SG1
Martin, DW; Owen, NT1
Carter, SK1
Altaner, C; Altanerová, V1
Cihák, A; Veselỳ, J1
Keefer, RC; Morris, HP; Webb, TE1
Cihák, A; Pitot, HC; Weiss, JW2
Cihák, A1

Reviews

4 review(s) available for azacitidine and Experimental Neoplasms

ArticleYear
5-Azacytidine. A new anticancer drug with effectiveness in acute myelogenous leukemia.
    Annals of internal medicine, 1976, Volume: 85, Issue:2

    Topics: Animals; Azacitidine; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Europe; Female; Humans; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Liver; Nausea; Neoplasms, Experimental; Neuromuscular Diseases; RNA, Messenger; United States; Vomiting

1976
Investigational drugs under study by the United States National Cancer Institute.
    Cancer treatment reviews, 1976, Volume: 3, Issue:1

    Topics: Acrylates; Alkylating Agents; Ancitabine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Chemical Phenomena; Chemistry; Chromomycins; Cisplatin; DNA, Neoplasm; Drug Evaluation, Preclinical; Etoposide; Humans; Ifosfamide; Leukemia L1210; Mice; Mitosis; National Institutes of Health (U.S.); Neoplasms; Neoplasms, Experimental; Razoxane; Tegafur; Teniposide; United States

1976
Resistance of mammalian tumour cells toward pyrimidine analogues. A review.
    Oncology, 1973, Volume: 28, Issue:3

    Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line; Cricetinae; Cytarabine; Deoxycytidine; Drug Resistance; Fluorouracil; Genetic Code; Leukemia, Experimental; Leukemia, Lymphoid; Mast-Cell Sarcoma; Mice; Mutation; Neoplasms, Experimental; Oncogenic Viruses; Phosphotransferases; Pyrimidines; Sarcoma, Experimental; Selection, Genetic; Thymidine Kinase; Uracil; Virus Replication

1973
Effects of 5-azacytidine on hepatic polyribosomes and maturation of ribosomal RNA.
    Acta biologica et medica Germanica, 1974, Volume: 33, Issue:5-6

    Topics: Animals; Azacitidine; Humans; Liver; Neoplasms, Experimental; Nucleic Acid Precursors; Polyribosomes; Rats; RNA, Messenger; RNA, Ribosomal

1974

Other Studies

62 other study(ies) available for azacitidine and Experimental Neoplasms

ArticleYear
Synthesis and antitumor activity of dihydro-5-azacytidine, a hydrolytically stable analogue of 5-azacytidine.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Agents; Azacitidine; Hydrolysis; Leukemia L1210; Leukemia, Experimental; Melanoma; Mice; Neoplasms, Experimental

1977
Decitabine reverses TGF-β1-induced epithelial-mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Survival; Decitabine; Epithelial-Mesenchymal Transition; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Neoplasms, Experimental; Transforming Growth Factor beta1; Tumor Cells, Cultured; Zinc Finger E-box-Binding Homeobox 1

2017
5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 02-20, Volume: 115, Issue:8

    Topics: Animals; Antineoplastic Agents; Azacitidine; Bacterial Toxins; Bone Marrow; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Exotoxins; Humans; Leukemia; Mice; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

2018
Epigenetic silencing of SFRP5 promotes the metastasis and invasion of chondrosarcoma by expression inhibition and Wnt signaling pathway activation.
    Chemico-biological interactions, 2018, Dec-25, Volume: 296

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cells, Cultured; Chondrosarcoma; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epigenesis, Genetic; Eye Proteins; Humans; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Structure-Activity Relationship; Wnt Signaling Pathway

2018
IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells.
    JCI insight, 2018, 12-06, Volume: 3, Issue:23

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Azacitidine; Cell Line, Tumor; Cytokines; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Drug Therapy; Epigenomics; Female; Humans; Immunotherapy; Interleukin-6; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neoplastic Stem Cells; Ovarian Neoplasms; Platinum; Retinal Dehydrogenase; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment; Up-Regulation

2018
Low dose decitabine treatment induces CD80 expression in cancer cells and stimulates tumor specific cytotoxic T lymphocyte responses.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; B7-1 Antigen; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Interleukin-2; K562 Cells; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Tumor Burden; U937 Cells

2013
Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:2

    Topics: Animals; Azacitidine; Blotting, Western; Cell Proliferation; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Female; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Real-Time Polymerase Chain Reaction; Thionucleosides; Tumor Cells, Cultured

2014
Aberrant hypomethylation-mediated AGR2 overexpression induces an aggressive phenotype in ovarian cancer cells.
    Oncology reports, 2014, Volume: 32, Issue:2

    Topics: Animals; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mucoproteins; Neoplasm Metastasis; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Oncogene Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Proteins

2014
The demethylating agent 5-Aza reduces the growth, invasiveness, and clonogenicity of uveal and cutaneous melanoma.
    Investigative ophthalmology & visual science, 2014, Aug-21, Volume: 55, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colony-Forming Units Assay; Decitabine; DNA Modification Methylases; DNA, Neoplasm; Humans; Melanoma; Melanoma, Cutaneous Malignant; Mice; Neoplasms, Experimental; Skin Neoplasms; Uveal Neoplasms

2014
DNA hypomethylation-mediated overexpression of carbonic anhydrase 9 induces an aggressive phenotype in ovarian cancer cells.
    Yonsei medical journal, 2014, Volume: 55, Issue:6

    Topics: Animals; Azacitidine; Carbonic Anhydrases; Carcinoma, Ovarian Epithelial; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Phenotype; Promoter Regions, Genetic; RNA, Messenger

2014
Upregulation of Key Molecules for Targeted Imaging and Therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:11

    Topics: Animals; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasms, Experimental; Organometallic Compounds; Pathology, Molecular; Positron-Emission Tomography; Receptors, Somatostatin; Reproducibility of Results; Sensitivity and Specificity; Up-Regulation

2016
Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer.
    Oncogene, 2009, Aug-06, Volume: 28, Issue:31

    Topics: Acetylation; Animals; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin; Cystatin M; Decitabine; Disease Progression; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasms, Experimental; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transplantation, Heterologous

2009
5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats.
    Toxicology letters, 2009, Dec-15, Volume: 191, Issue:2-3

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blood Urea Nitrogen; Blotting, Western; Breast Neoplasms; Cell Nucleus; Cisplatin; Colonic Neoplasms; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Synergism; Drug Therapy, Combination; Female; Histones; Kidney Diseases; Male; Mammary Neoplasms, Experimental; Metallothionein; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley

2009
Generation of antigen-presenting cells from tumor-infiltrated CD11b myeloid cells with DNA demethylating agent 5-aza-2'-deoxycytidine.
    Cancer immunology, immunotherapy : CII, 2010, Volume: 59, Issue:5

    Topics: Animals; Antigen-Presenting Cells; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cancer Vaccines; CD11b Antigen; Cell Differentiation; Cell Separation; Cytokines; Decitabine; Female; Flow Cytometry; Immunotherapy; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid Cells; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction

2010
Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.
    Neoplasia (New York, N.Y.), 2010, Volume: 12, Issue:1

    Topics: Adult; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cerebellar Neoplasms; CpG Islands; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Loss of Heterozygosity; Medulloblastoma; Mice; Mice, Nude; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous

2010
5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors.
    The Prostate, 2010, Volume: 70, Issue:11

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Anilides; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Humans; Male; Mice; Mice, Nude; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Random Allocation; Receptors, Androgen; Tosyl Compounds

2010
Immunotherapy augments the effect of 5-azacytidine on HPV16-associated tumours with different MHC class I-expression status.
    British journal of cancer, 2011, Nov-08, Volume: 105, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; DNA Primers; Enzyme-Linked Immunosorbent Assay; Histocompatibility Antigens Class I; Human papillomavirus 16; Immunotherapy; Male; Methylation; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Real-Time Polymerase Chain Reaction

2011
Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo.
    Journal of immunology (Baltimore, Md. : 1950), 2012, May-01, Volume: 188, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Adoptive Transfer; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; bcl-X Protein; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colonic Neoplasms; Decitabine; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Membrane Proteins; Mice; Mitochondrial Proteins; Neoplasm Metastasis; Neoplasms, Experimental; Proto-Oncogene Proteins; Tumor Escape; Vorinostat

2012
THE EFFECT OF 6-AZAURIDINE AND 6-AZACYTIDINE ON THE INTRACELLULAR SYNTHESIS OF RNA IN FOWL LEUKEMIC AND NORMAL MYELOBLASTS IN VITRO.
    Acta biologica et medica Germanica, 1964, Volume: 12

    Topics: Animals; Antimetabolites; Autoradiography; Azacitidine; Azauridine; Bone Marrow Examination; Cytoplasm; Granulocyte Precursor Cells; In Vitro Techniques; Leukemia; Leukemia, Experimental; Neoplasms, Experimental; Nucleosides; Poultry; Research; RNA; RNA, Neoplasm

1964
Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours.
    Immunology, 2008, Volume: 123, Issue:2

    Topics: Animals; Antigen Presentation; Apoptosis; Azacitidine; Enzyme Inhibitors; Epigenesis, Genetic; Genes, MHC Class I; Histones; Human papillomavirus 16; Humans; Hydroxamic Acids; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Papillomavirus Infections; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Up-Regulation

2008
Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer.
    BMC cancer, 2008, May-02, Volume: 8

    Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor Proteins; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Administration Schedule; Epigenesis, Genetic; Genomic Imprinting; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Mice; Neoplasms, Experimental; Tumor Stem Cell Assay

2008
Effects of 5-azacytidine on transfer RNA modification: comparative study on normal and malignant tissues.
    Life sciences, 1980, Aug-18, Volume: 27, Issue:7

    Topics: Animals; Azacitidine; Cytidine; Mice; Neoplasms, Experimental; Rats; RNA, Transfer; tRNA Methyltransferases

1980
Synthesis and biological activity of 2'-deoxy-6-methyl-5-azacytidine and its alpha-D-anomer.
    Nucleic acids symposium series, 1981, Issue:9

    Topics: Animals; Azacitidine; Drug Evaluation, Preclinical; Escherichia coli; Indicators and Reagents; Neoplasms, Experimental

1981
Azacytidine-induced tumorigenesis of CHEF/18 cells: correlated DNA methylation and chromosome changes.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:21

    Topics: Adipose Tissue; Animals; Azacitidine; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cricetinae; DNA, Neoplasm; Karyotyping; Methylation; Mice; Mice, Nude; Neoplasms, Experimental; Trisomy

1983
5-azacytidine induction of thymidine kinase in a spontaneously enzyme-deficient murine tumor line.
    Experimental cell research, 1984, Volume: 150, Issue:2

    Topics: Animals; Azacitidine; Cell Division; Cell Line; DNA, Neoplasm; Enzyme Induction; Methylation; Mice; Neoplasms, Experimental; Thymidine Kinase

1984
Induction of the metastatic phenotype in a mouse tumor model by 5-azacytidine, and characterization of an antigen associated with metastatic activity.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Azacitidine; DNA, Neoplasm; Methylation; Mice; Neoplasm Metastasis; Neoplasms, Experimental

1984
Genetic analysis of tumorigenesis: XVI. Chromosome changes in azacytidine- and insulin-induced tumorigenesis.
    Somatic cell and molecular genetics, 1984, Volume: 10, Issue:5

    Topics: Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Cricetinae; Cricetulus; Embryo, Mammalian; Insulin; Karyotyping; Neoplasms, Experimental

1984
The tumorigenicity of 5-azacytidine in the male Fischer rat.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: Animals; Azacitidine; DNA; Kidney Neoplasms; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphatic Diseases; Male; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Skin Neoplasms; Testicular Neoplasms

1984
Human fibroblasts (KMST-6/RAS line) transformed with 60Co gamma-rays and c-Ha-ras oncogene constitutively produce a large amount of human granulocyte-colony stimulating factor (G-CSF).
    Human cell, 1994, Volume: 7, Issue:2

    Topics: Animals; Azacitidine; Butyrates; Cell Line; Cell Transformation, Neoplastic; Cobalt Radioisotopes; Dexamethasone; Fibroblasts; Gamma Rays; Genes, ras; Granulocyte Colony-Stimulating Factor; Humans; Mice; Mice, Nude; Neoplasms, Experimental

1994
Phenylacetate in chemoprevention: in vitro and in vivo suppression of 5-aza-2'-deoxycytidine-induced carcinogenesis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:8

    Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Azacitidine; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Chemoprevention; Clone Cells; Collagen; Decitabine; DNA Methylation; Drug Combinations; Female; Genes, ras; Laminin; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasms, Experimental; Phenylacetates; Proteoglycans

1995
Chemotherapeutic drugs increase killing of tumor cells by antibody and complement.
    Science (New York, N.Y.), 1975, Apr-04, Volume: 188, Issue:4183

    Topics: Animals; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cell Line; Complement System Proteins; Cyclophosphamide; Cytarabine; Fluorouracil; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Nitrosamines; Vincristine

1975
Effects of 5-azacytidine on nucleolar RNA and the preribosomal particles in Novikoff hepatoma cells.
    Biochemistry, 1975, Jan-28, Volume: 14, Issue:2

    Topics: Animals; Azacitidine; Carcinoma, Hepatocellular; Cell Nucleolus; Cells, Cultured; Guanosine Triphosphate; Liver Neoplasms; Neoplasms, Experimental; Rats; Ribosomes; RNA, Neoplasm; RNA, Ribosomal

1975
Early temporal changes in the uridine kinase isozyme profile of the Novikoff hepatoma in response to 5-azacytidine treatment.
    Biochemical pharmacology, 1975, Jul-15, Volume: 24, Issue:13-14

    Topics: Aging; Animals; Azacitidine; Carcinoma, Hepatocellular; DNA Replication; Dose-Response Relationship, Drug; Drug Resistance; Female; Isoenzymes; Liver Neoplasms; Neoplasms, Experimental; Phosphotransferases; Rats; Thymidine; Time Factors; Tritium; Uridine Kinase

1975
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
    Cancer research, 1975, Volume: 35, Issue:11 Pt 1

    Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine

1975
Effect of metabolic inhibitors on the ability of tumor cells to express antigen and bind complement components C4 and C3.
    Cancer research, 1975, Volume: 35, Issue:11 Pt 1

    Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Binding Sites, Antibody; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Complement C3; Complement C4; Complement System Proteins; Dactinomycin; Doxorubicin; Guinea Pigs; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Puromycin

1975
Transformation of BHK 21/13 cells by chemical carcinogens and mutagens.
    Neoplasma, 1975, Volume: 22, Issue:6

    Topics: 4-Nitroquinoline-1-oxide; Animals; Azacitidine; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Methylcholanthrene; Mutagens; Neoplasms, Experimental; Retroviridae

1975
Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review).
    Neoplasma, 1976, Volume: 23, Issue:3

    Topics: Animals; Azacitidine; Azauridine; Molecular Weight; Neoplasms, Experimental; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Species Specificity; Uridine; Uridine Kinase; Virus Diseases

1976
Uridine kinase activities in normal and neoplastic lymphoid cells.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: Animals; Azacitidine; B-Lymphocytes; Carcinoma, Hepatocellular; Cats; Enzyme Induction; Humans; Isoenzymes; Leukemia, Experimental; Leukemia, Lymphoid; Liver Neoplasms; Lymphocyte Activation; Lymphocytes; Lymphoma, Non-Hodgkin; Male; Mast-Cell Sarcoma; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Phosphotransferases; Rats; T-Lymphocytes; Uridine Kinase

1977
In vitro cytotoxic and biochemical effects of 5-aza-2'-deoxycytidine.
    Cancer research, 1977, Volume: 37, Issue:6

    Topics: Azacitidine; Cell Division; Cell Survival; Cells, Cultured; Cytidine; Deoxycytidine; DNA, Neoplasm; Fibrosarcoma; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm

1977
Alterations in [3H]thymidine incorporation into DNA and [3H]uridine incorporation into RNA induced by 5-azacytidine in vivo.
    Biochemical pharmacology, 1978, Mar-01, Volume: 27, Issue:5

    Topics: Animals; Ascites; Azacitidine; Bone Marrow; DNA; Female; Intestinal Mucosa; Mice; Mice, Inbred Strains; Neoplasms, Experimental; RNA; Thymidine; Time Factors; Uridine

1978
Metabolism and cytotoxicity of 5-azacytidine in cultured Novikoff rat hepatoma and P388 mouse leukemia cells and their enhancement by preincubation with pyrazofurin.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Amides; Animals; Antibiotics, Antineoplastic; Azacitidine; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Cytidine; DNA, Neoplasm; Drug Synergism; Leukemia, Experimental; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Phosphates; Pyrazoles; Ribonucleosides; Ribose; RNA, Neoplasm; Uridine

1978
Evaluation of a "nude" mouse-human tumor panel as a predictive secondary screen for cancer chemotherapeutic agents.
    Journal of the National Cancer Institute, 1979, Volume: 63, Issue:5

    Topics: Animals; Antineoplastic Agents; Azacitidine; Carmustine; Dacarbazine; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Female; Humans; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental

1979
Effect of myogenic determination on tumorigenicity of chemically transformed 10T1/2 cells.
    Molecular carcinogenesis, 1991, Volume: 4, Issue:2

    Topics: Animals; Azacitidine; Blotting, Northern; Cell Differentiation; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA-Binding Proteins; Fluorescent Antibody Technique; Genetic Vectors; Methylcholanthrene; Mice; Muscle Proteins; Muscles; MyoD Protein; Myosins; Neoplasms, Experimental; RNA, Neoplasm; Transfection

1991
Diaplacental carcinogenic effects of 5-azacytidine in NMRI-mice.
    Cancer letters, 1985, Volume: 27, Issue:1

    Topics: Animals; Azacitidine; Fetus; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma, Experimental; Soft Tissue Neoplasms

1985
Induction of thymidine kinase activity in a spontaneously enzyme-deficient murine tumor cell line by exposure in vivo to the DNA-hypomethylating agent 5-aza-2'-deoxycytidine: implications for mechanisms of tumor progression.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 1

    Topics: Animals; Azacitidine; Cell Line; Decitabine; DNA; Enzyme Induction; Male; Methylation; Mice; Mice, Inbred DBA; Mutation; Neoplasms, Experimental; Thymidine Kinase

1985
Arabinofuranosyl-5-azacytosine: antitumor and cytotoxic properties.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: Animals; Azacitidine; Cell Cycle; Cell Differentiation; Cell Survival; Cells, Cultured; Humans; Mice; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Vidarabine

1986
DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture.
    The Journal of biological chemistry, 1986, Feb-05, Volume: 261, Issue:4

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cattle; Cells, Cultured; Cricetinae; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Mesocricetus; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats

1986
On the possible contribution of DNA hypomethylation to the induction of high frequency and heritable drug-induced alterations in the malignant phenotype.
    Progress in clinical and biological research, 1986, Volume: 212

    Topics: Alkylating Agents; Animals; Azacitidine; Cell Line; DNA, Neoplasm; Gene Amplification; Humans; Methylation; Mice; Mutagens; Mutation; Neoplasms; Neoplasms, Experimental; Phenotype; Thymidine Kinase

1986
Dissociation of contact-noninhibition in vitro and tumorigenicity in vivo.
    Cell biology international reports, 1986, Volume: 10, Issue:10

    Topics: Animals; Azacitidine; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; Contact Inhibition; Furans; Mice; Neoplasms, Experimental

1986
Suppression of tumorigenicity mediated by 5-azacytidine and associated with increased chromosome number.
    Journal of the National Cancer Institute, 1987, Volume: 78, Issue:4

    Topics: Animals; Azacitidine; Cell Line; Chromosomes; DNA, Neoplasm; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental

1987
Carcinogenicity and haemoglobin synthesis induction by cytidine analogues.
    British journal of cancer, 1988, Volume: 57, Issue:4

    Topics: Animals; Azacitidine; Cell Survival; Dose-Response Relationship, Drug; Female; Hemoglobins; Leydig Cell Tumor; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Rats; Rats, Inbred F344; Sheep; Testicular Neoplasms

1988
Modulation of the beta-adrenergic receptor-coupled adenylate cyclase by chemical inducers of differentiation: effects on beta receptors and the inhibitory regulatory protein Gi.
    Journal of receptor research, 1988, Volume: 8, Issue:5

    Topics: Acetamides; Adenylyl Cyclases; Azacitidine; Butyrates; Butyric Acid; Cell Differentiation; Cells, Cultured; Enzyme Induction; GTP-Binding Proteins; HeLa Cells; Humans; Neoplasms, Experimental; Puromycin; Puromycin Aminonucleoside; Receptors, Adrenergic, beta

1988
Anti-tumor surveillance of non-contact-inhibited transformed cell lines.
    International journal of cancer, 1988, Sep-15, Volume: 42, Issue:3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Antigens, Neoplasm; Azacitidine; Cell Line, Transformed; Cell Transformation, Neoplastic; Histocompatibility Antigens; Immunity, Cellular; Immunologic Surveillance; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Phenotype

1988
Reversibility of progression of the transformed phenotype in Ad5-transformed rat embryo cells.
    Science (New York, N.Y.), 1985, May-31, Volume: 228, Issue:4703

    Topics: Adenoviruses, Human; Animals; Azacitidine; Cell Division; Cell Transformation, Viral; Cells, Cultured; DNA, Neoplasm; DNA, Viral; Gene Expression Regulation; Genes, Viral; Methylation; Mice; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Transcription, Genetic

1985
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
    The Journal of biological chemistry, 1972, Sep-10, Volume: 247, Issue:17

    Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; Feedback; Formates; Glycine; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Purines; Rats; Ribonucleotides; Ribose; Tetrahydrofolates; Tritium

1972
New drugs on the horizon in bronchogenic carcinoma.
    Cancer, 1972, Volume: 30, Issue:5

    Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Bleomycin; Carcinoma, Bronchogenic; Carmustine; Cyclic P-Oxides; Cyclophosphamide; Dimethylamines; Doxorubicin; Ethylamines; Evaluation Studies as Topic; Humans; Ketones; Lung Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Organophosphorus Compounds; Oxazines; Piperazines; Platinum; Triazines

1972
Characterization of chicken sarcoma viruses induced with chemical carcinogens and mutagens in transformed hamster cells.
    Neoplasma, 1972, Volume: 19, Issue:5

    Topics: Alpharetrovirus; Animals; Azacitidine; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Cricetinae; DNA Nucleotidyltransferases; Genetic Code; Methylcholanthrene; Mutation; Neoplasms, Experimental; Quinolines; RNA, Viral

1972
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells.
    Archives of biochemistry and biophysics, 1974, Volume: 160, Issue:1

    Topics: Animals; Azacitidine; Azaguanine; Carcinoma, Hepatocellular; Cells, Cultured; Cytidine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Guanosine; Isotope Labeling; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine

1974
5-azacytidine-modified patterns of uridine kinase activities in normal and neoplastic tissues.
    Cancer research, 1974, Volume: 34, Issue:9

    Topics: Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Enzyme Induction; Liver; Liver Neoplasms; Male; Mice; Neoplasms, Experimental; Phosphotransferases; Rats; Time Factors

1974
Characterization of polyribosomes and maturation of ribosomal RNA in hepatoma cells treated with 5-azacytidine.
    Cancer research, 1974, Volume: 34, Issue:11

    Topics: Animals; Azacitidine; Carcinoma, Hepatocellular; Cell Fractionation; Cells, Cultured; Cytoplasm; Leucine; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Polyribosomes; Rats; RNA, Ribosomal; Time Factors; Tritium

1974
Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.
    Archives of biochemistry and biophysics, 1974, Volume: 165, Issue:2

    Topics: Animals; Azacitidine; Azaguanine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Transcription, Genetic; Tritium; Uridine

1974
Biological effects of 5-azacytidine in eukaryotes.
    Oncology, 1974, Volume: 30, Issue:5

    Topics: Animals; Azacitidine; DNA; DNA, Bacterial; DNA, Viral; Drug Resistance; Embryo, Mammalian; Enzyme Induction; Gastric Juice; Humans; Leukemia, Lymphoid; Liver; Liver Regeneration; Neoplasms; Neoplasms, Experimental; Polyamines; Polyribosomes; Protein Biosynthesis; RNA; Spleen; Tyrosine Transaminase; Uridine Kinase

1974