azacitidine and Experimental Hepatoma

azacitidine has been researched along with Experimental Hepatoma in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199010 (41.67)18.7374
1990's7 (29.17)18.2507
2000's5 (20.83)29.6817
2010's1 (4.17)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Audsley, KM; Callus, BA; Finch-Edmondson, ML; Passman, AM; Strauss, RP; van Vuuren, JH; Yeoh, GC1
Kang, YH; Kuang, JY; Mai, L; Xie, QF; Xu, QH; Yang, L; Zhang, SQ1
Igarashi, M; Nakae, D; Takahashi, M; Uematsu, F; Yoshida, M1
Chagas, CE; Moreno, FS; Ong, TP; Sampaio, AR1
Goss, SJ1
Carr, BI; Reilly, JG; Riggs, AD1
Delers, A; Saggioro, D; Szpirer, C; Szpirer, J1
Lan, NC1
Carr, BI; Reilly, JG; Riggs, A; Smith, SS; Winberg, C1
Benvenuto, G; Bruni, CB; Chiariotti, L; Colantuoni, V; Rossi, E; Salvatore, P; Zarrilli, R1
Ayté, J; Gil-Gómez, G; Hegardt, FG1
Späth, GF; Weiss, MC1
Fukui, H; Ikenaka, K; Kikukawa, M; Kuriyama, S; Nakatani, T; Sakamoto, T; Toyokawa, Y; Tsujii, T; Tsujinoue, H1
Fukunishi, Y; Hayashizaki, Y; Held, WA; Itoh, M; Kawai, J; Komatsu, S; Muramatsu, M; Okazaki, Y; Shibata, K; Tateno, M1
Bai, S; Datta, J; Dong, X; Ghoshal, K; Jacob, ST; Majumder, S; Plass, C; Quan, N1
Ghoshal, K; Jacob, ST; Majumder, S1
Anderson, EP; Liacouras, AS1
Foster, R; Gedamu, L; Jahroudi, N1
Daino, L; Feo, F; Lai, P; Pascale, R; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM; Vannini, MG1
Kurosawa, T; Ookawara, T; Sugiyama, T; Suzuki, K; Taniguchi, N1
Geber, E; Lehmacher, W; Schmahl, W1
Gonzalez, FJ; Nebert, DW; Peterson, TC1
Asmeron, Y; Carr, BI; Rahbar, S; Riggs, A; Winberg, CD1
Denda, A; Rajalakshmi, S; Rao, PM; Sarma, DS1

Other Studies

24 other study(ies) available for azacitidine and Experimental Hepatoma

ArticleYear
Loss of ARF/INK4A Promotes Liver Progenitor Cell Transformation Toward Tumorigenicity Supporting Their Role in Hepatocarcinogenesis.
    Gene expression, 2020, 06-12, Volume: 20, Issue:1

    Topics: Animals; Azacitidine; Cell Line, Transformed; Cell Transformation, Neoplastic; CRISPR-Cas Systems; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Epithelial-Mesenchymal Transition; Gene Deletion; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Genes, p16; Liver; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Phenotype; Snail Family Transcription Factors; Stem Cells; Tumor Stem Cell Assay; Vimentin

2020
[Small interfering RNA targeting to hepatitis B virus X gene and 5-aza-2'-deoxycytidineon inhibited growth of the subcutaneous implanted tumor of hepatocellular carcinoma in nude mice].
    Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2012, Volume: 26, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; Genes, p16; Hep G2 Cells; Humans; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; RNA, Small Interfering; Trans-Activators; Viral Regulatory and Accessory Proteins

2012
Methylation of neutral endopeptidase 24.11 promoter in rat hepatocellular carcinoma.
    Cancer science, 2006, Volume: 97, Issue:7

    Topics: Animals; Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Neprilysin; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic

2006
Vitamin A and beta-carotene inhibitory effect during 1,2-dimethylhydrazine induced hepatocarcinogenesis potentiated by 5-azacytidine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Azacitidine; beta Carotene; DNA Repair; gamma-Glutamyltransferase; Liver Neoplasms, Experimental; Male; Rats; Rats, Wistar; Vitamin A

2007
The associated reactivation of two X-linked genes. The spontaneous and azacytidine-induced reexpression of ornithine transcarbamoylase and glucose-6-phosphate dehydrogenase in a rat hepatoma.
    Journal of cell science, 1984, Volume: 72

    Topics: Animals; Azacitidine; Cell Line; Enzyme Activation; Female; Gene Expression Regulation; Genes; Glucosephosphate Dehydrogenase; Liver Neoplasms, Experimental; Ornithine Carbamoyltransferase; Rats; X Chromosome

1984
5-Azacytidine. Promoting activity for rat hepatocellular carcinoma.
    IARC scientific publications, 1984, Issue:56

    Topics: Animals; Azacitidine; Carcinogens; Diethylnitrosamine; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred F344

1984
Spontaneous and 5-azacytidine-induced reexpression of ornithine carbamoyl transferase in hepatoma cells.
    Molecular and cellular biology, 1984, Volume: 4, Issue:4

    Topics: Animals; Azacitidine; Cell Differentiation; Cell Line; Gene Expression Regulation; Liver; Liver Neoplasms, Experimental; Methylation; Ornithine Carbamoyltransferase; Rats

1984
The effects of 5-azacytidine on the expression of the rat growth hormone gene. Methylation modulates but does not control growth hormone gene activity.
    The Journal of biological chemistry, 1984, Sep-25, Volume: 259, Issue:18

    Topics: Adrenocorticotropic Hormone; Animals; Azacitidine; Cell Line; DNA; Gene Expression Regulation; Growth Hormone; Liver Neoplasms, Experimental; Methylation; Mice; Nucleic Acid Precursors; Pituitary Neoplasms; Prolactin; Rats; RNA Precursors; RNA, Messenger

1984
The tumorigenicity of 5-azacytidine in the male Fischer rat.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: Animals; Azacitidine; DNA; Kidney Neoplasms; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphatic Diseases; Male; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Skin Neoplasms; Testicular Neoplasms

1984
Activation of the galectin-1 (L-14-I) gene from nonexpressing differentiated cells by fusion with undifferentiated and tumorigenic cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:7

    Topics: Alleles; Animals; Azacitidine; Base Sequence; Cell Differentiation; Cell Fusion; Cells, Cultured; Galectin 1; Gene Expression Regulation, Neoplastic; Genes, Dominant; Hemagglutinins; Humans; Liver; Liver Neoplasms, Experimental; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; Osteosarcoma; Rats; Tumor Cells, Cultured

1994
Methylation of the regulatory region of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene leads to its transcriptional inactivation.
    The Biochemical journal, 1993, Nov-01, Volume: 295 ( Pt 3)

    Topics: Animals; Animals, Newborn; Azacitidine; DNA; Exons; Fetus; Gene Expression; Hydroxymethylglutaryl-CoA Synthase; Kidney; Liver Neoplasms, Experimental; Male; Methylation; Mitochondria, Liver; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Restriction Mapping; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1993
Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells.
    Molecular and cellular biology, 1997, Volume: 17, Issue:4

    Topics: alpha 1-Antitrypsin; Animals; Azacitidine; Base Sequence; Cell Differentiation; Dexamethasone; DNA Methylation; DNA-Binding Proteins; DNA, Complementary; Gene Expression; Genetic Markers; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Hepatocyte Nuclear Factor 4; Liver; Liver Neoplasms, Experimental; Nuclear Proteins; Phenotype; Phosphoproteins; Rats; Transcription Factors; Transfection; Tumor Cells, Cultured

1997
Expression of a retrovirally transduced gene under control of an internal housekeeping gene promoter does not persist due to methylation and is restored partially by 5-azacytidine treatment.
    Gene therapy, 1998, Volume: 5, Issue:10

    Topics: Animals; Antimetabolites; Azacitidine; Blotting, Southern; DNA Methylation; Enzyme Inhibitors; Ganciclovir; Gene Expression; Genetic Therapy; Genetic Vectors; Liver Neoplasms, Experimental; Mice; Promoter Regions, Genetic; Retroviridae; Thymidine Kinase; Transfection

1998
Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice.
    Cancer research, 2001, Feb-01, Volume: 61, Issue:3

    Topics: Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome, Human; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Neuroblastoma; Open Reading Frames; Promoter Regions, Genetic; Repressor Proteins; RNA, Messenger; Snail Family Transcription Factors; Transcription Factors; Zinc Fingers

2001
Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma.
    The Journal of biological chemistry, 2002, May-03, Volume: 277, Issue:18

    Topics: Animals; Azacitidine; Base Sequence; Carrier Proteins; Cell Nucleus; Dinucleoside Phosphates; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; DNA-Cytosine Methylases; Gene Expression Regulation, Neoplastic; Gene Silencing; Liver; Liver Neoplasms, Experimental; Metallothionein; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity

2002
Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells.
    Methods in enzymology, 2002, Volume: 353

    Topics: Animals; Azacitidine; Base Sequence; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Liver Neoplasms, Experimental; Metallothionein; Metals; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Sarcoma; Sulfites; Tumor Cells, Cultured

2002
Uridine-cytidine kinase. IV. Kinetics of the competition between 5-azacytidine and the two natural substrates.
    Molecular pharmacology, 1979, Volume: 15, Issue:2

    Topics: Animals; Azacitidine; Cytidine; In Vitro Techniques; Kinetics; Liver Neoplasms, Experimental; Mice; Models, Biological; Phosphotransferases; Substrate Specificity; Uridine; Uridine Kinase

1979
5-Azacytidine increases the total cellular copper content and basal level metallothionein mRNA accumulation of human Hep G2 cells.
    Biochimica et biophysica acta, 1991, Mar-26, Volume: 1088, Issue:3

    Topics: Animals; Azacitidine; Blotting, Northern; Copper; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Liver Neoplasms, Experimental; Metallothionein; RNA, Messenger; Spectrophotometry, Atomic; Tumor Cells, Cultured

1991
Reversal by 5-azacytidine of the S-adenosyl-L-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis.
    Cancer letters, 1991, Volume: 56, Issue:3

    Topics: Adenosine; Animals; Azacitidine; Biomarkers, Tumor; Deoxyadenosines; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides

1991
High sensitivity to 5-azacytidine in LEC rats, a strain with a metabolic predisposition to hepatitis and hepatoma: possible involvement of DNA methylation in the expression of cytochrome P-450 and gamma-glutamyl transpeptidase.
    Biochemistry international, 1991, Volume: 23, Issue:1

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cytochrome P-450 Enzyme System; Cytosine; Disease Susceptibility; DNA; DNA (Cytosine-5-)-Methyltransferases; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Hepatitis, Animal; Liver; Liver Neoplasms, Experimental; Methylation; Rats; Rats, Mutant Strains

1991
Diaplacental carcinogenic effects of 5-azacytidine in NMRI-mice.
    Cancer letters, 1985, Volume: 27, Issue:1

    Topics: Animals; Azacitidine; Fetus; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma, Experimental; Soft Tissue Neoplasms

1985
Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: Animals; Azacitidine; Base Sequence; Cells, Cultured; Cytochrome P-450 Enzyme System; Deoxyribonuclease HpaII; DNA; DNA Restriction Enzymes; Gene Amplification; Genes; Isoenzymes; Liver Neoplasms, Experimental; Methylation; Mice; Mutation; Polychlorinated Dibenzodioxins

1986
Carcinogenicity and haemoglobin synthesis induction by cytidine analogues.
    British journal of cancer, 1988, Volume: 57, Issue:4

    Topics: Animals; Azacitidine; Cell Survival; Dose-Response Relationship, Drug; Female; Hemoglobins; Leydig Cell Tumor; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Rats; Rats, Inbred F344; Sheep; Testicular Neoplasms

1988
5-azacytidine potentiates initiation induced by carcinogens in rat liver.
    Carcinogenesis, 1985, Volume: 6, Issue:1

    Topics: Animals; Azacitidine; Carcinogens; Cocarcinogenesis; DNA; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Methylation; Rats

1985