Compounds > azacitidine

azacitidine and Colonic Neoplasms

azacitidine has been researched along with Colonic Neoplasms in 87 studies

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-19905 (5.75)18.7374
1990's9 (10.34)18.2507
2000's39 (44.83)29.6817
2010's33 (37.93)24.3611
2020's1 (1.15)2.80

Authors

AuthorsStudies
Cheong, HT; Jung, BD; Kim, DY; Kimura, K; Ra, CS1
Chen, Q; Hu, YH; Li, XM; Li, XN; Lin, C; Lu, YX; Zhang, F; Zhang, JM; Zhang, W; Zhang, WJ1
Fukuda, M; Hosokawa, M; Iwakawa, S; Masuda, A; Tanaka, S; Ueda, K1
Chen, JK; Lai, Y; Liang, WL; Lin, Y; Wang, HY; Yan, FD; Yu, Z; Yuan, YH; Zhong, W1
Antoniou, E; Davidson, NO; Denoya, P; Li, E; McCombie, WR; Williams, J; Wu, S; Xu, X; Zhang, Y; Zhu, W1
Ikehata, M; Iwakawa, S; Ogawa, M; Tanaka, S; Ueda, K; Yamada, Y1
Carroll, RJ; Chapkin, RS; Cho, Y; Davidson, LA; Lupton, JR; Turner, ND1
Chen, PJ; Huang, GB; Li, B; Lou, YF; Luo, XY; Yu, XR; Zheng, DQ; Zou, ZZ1
Glazer, PM; Lu, Y; Turker, MS; Wajapeyee, N1
Chen, C; Chen, Z; Na, H; Ren, S; Sun, J; Wang, B; Yan, L; Zhu, Z; Zuo, Y1
Barra, V; Cilluffo, D; Costa, G; Di Leonardo, A; Lentini, L1
Chen, ST; Hsieh, YY; Huang, TC; Jhan, JY; Lo, HL; Yang, PM1
Angriman, I; Basato, S; Brun, P; Castagliuolo, I; Castoro, C; Erroi, F; Scarpa, M1
Knox, SJ; Ning, S; Nolley, R; Oronsky, B; Peehl, DM; Scicinski, J; Zhao, H1
Amri, R; Arora, KS; Aryee, MJ; Berger, DL; Bledsoe, JR; Desai, N; Deshpande, V; Ferrone, CR; Greenbaum, BD; MacKenzie, OC; Mino-Kenudson, M; Rajurkar, M; Rivera, MN; Sajed, D; Sil, S; Solovyov, A; Tai, E; Ting, DT1
Choi, CH; Kim, KJ; Lee, TB; Min, YD; Park, JH1
Bonazzi, VF; Hayward, NK; Irwin, D1
Kim, DH; Kim, SJ; Lee, BB; Lee, EJ; Park, J; Park, YD1
Cui, J; Huang, Q; Lai, M; Lin, J; Ma, Y; Ruan, W2
Bosch, LJ; Carvalho, B; de Bruïne, AP; Derks, S; Herman, JG; Meijer, GA; Moerkerk, PT; Mongera, S; Niessen, HE; van den Bosch, SM; van Engeland, M; Voncken, JW1
Brooke, DG; Datta, J; Denny, WA; Gamage, SA; Ghoshal, K; Jacob, ST; Phiasivongsa, P; Redkar, S1
Jagodzinski, PP; Piotrowska, H1
Li, BH; Li, F; Li, PD; Liu, XH; Xu, SB; Yang, XZ; Yuan, J; Yuan, Q; Zhang, WJ; Zhang, Y1
Cruickshanks, HA; Tufarelli, C1
Ali, IY; Gupta, C; Gupta, J; Tikoo, K1
Hagemann, S; Hanna, K; Lyko, F; Schaefer, M1
Huo, JR; Ren, JZ2
Bélanger, AS; Guillemette, C; Harvey, M; Tojcic, J1
Egan, LJ; Foran, E; Garrity-Park, MM; Limburg, PJ; Mureau, C; Newell, J; Smyrk, TC1
Ahmed, S; Boumber, YA; He, R; Issa, JP; Jelinek, J; Qin, T; Shu, J; Si, J1
Kortsaris, A; Krupitza, G; Mader, RM; Mikulits, W; Schmidt, WM; Steger, GG; Tentes, IK1
Couillard, J; Estève, PO; Pradhan, S; St-Pierre, Y1
Bi, F; Deng, Q; Huang, CM; Li, AJ; Li, ZP; Liu, Z; Tang, QL; Zhong, RM1
Adachi, Y; Hizaki, K; Imai, K; Kato, N; Nakazawa, M; Sanchez, JV; Sasaki, S; Shinomura, Y; Sukawa, Y; Suzuki, H; Taniguchi, H; Tanuma, T; Yamamoto, H1
Gamo, T; Habano, W; Otsuka, K; Ozawa, S; Sugai, T; Terashima, J; Wakabayashi, G1
Clark, SJ; Coolen, MW; Custodio, J; Esteller, M; Mayor, R; Muñoz, M; Peinado, MA1
Li, L; Liu, X; Tu, B; Wang, D; Wang, H; Wang, L; Zheng, Z; Zhu, WG1
Esteban, S; Fernandez-Suarez, A; González-Peramato, P; Moya, P; Sánchez-Carbayo, M; Vidaurreta, M1
Ikehata, M; Iwakawa, S; Ueda, K1
Bardhan, K; Liu, K; McGaha, TL; Torres, CM; Yang, D; Zimmerman, M1
Chen, H; Li, Q1
Fetahu, ISh; Höbaus, J; Kallay, E; Khorchide, M; Manhardt, T1
Chen, Y; Ding, J; Feng, JM; Huang, YR; Jiang, Y; Li, JX; Miao, ZH; Tong, LJ; Zhang, J1
Bollag, G; Bornman, WG; Davies, MA; Dayyani, F; Desai, J; Gallick, GE; Gopal, YN; Jiang, ZQ; Kopetz, S; Lemos, R; Mao, M; Mariadason, JM; Mills, GB; Powis, G; Tang, XM; Tian, F; Tsao, CC; Wistuba, II1
Durkin, ME; Popescu, NC; Yuan, BZ1
Berczi, L; Brent, TP; Danam, RP; Houghton, JA; Howell, SR; Kopper, L; Petak, I; Tillman, DM; Vernes, R1
Casey, G; Issa, JP; Kasturi, L; Li, H; Lutterbaugh, J; Markowitz, SD; Myeroff, L; Plass, C; Pretlow, TP; Rerko, RM; Romero, MF; Smiraglia, D; Willis, J; Willson, JK1
Fearon, ER; Hinoi, T; Loda, M1
Berx, G; Cirnes, L; Correia da Rocha, AS; Debruyne, PR; Li, X; Mareel, MM; Pocard, M; Poupon, MF; van Roy, FM; Vermeulen, SJ1
Jaszewski, R; Kucuk, O; Majumdar, AP; Nagothu, KK; Rishi, AK1
Chen, YX; Fang, JY; Gu, WQ; Lu, J; Lu, LG; Lu, R; Yang, L; Zhu, HY1
Kramer, PM; Pereira, MA; Tao, L; Wang, W1
Chen, JX; Cui, XY; Fu, PF; Wang, T1
Biesová, Z; Jakubicková, L; Kettmann, R; Pastorek, J; Pastoreková, S1
Bernal, ML; Gomez, A; Ingelman-Sundberg, M; Johansson, I; Karlgren, M; Oliw, E; Ramón y Cajal, S; Rodriguez-Antona, C; Stark, K; Svärd, J1
Ahlquist, DA; Burgart, LJ; Harrington, JJ; Klatt, KK; Lesche, R; Lewin, J; Lofton-Day, C; Molina, JR; Osborn, NK; Zou, H1
Chim, CS; He, H; Jiang, SH; Kung, HF; Leung, SY; Lin, MC; Sun, YW; Tu, SP; Wang, J; Wong, BC; Yang, Y; Yu, LF; Yuen, ST; Zeng, H; Zou, B1
Euhus, DM; Fong, KM; Gao, B; Gazdar, AF; Gerald, W; Girard, L; Jiang, A; Kim, YH; Lam, CL; Lewis, CM; Minna, JD; Nanda, R; Olopade, OI; Perou, CM; Pollack, JR; Sato, M; Shames, DS; Shay, JW; Shivapurkar, N; Shyr, Y; Wong, M1
Enomoto, M; Iida, S; Ishiguro, M; Kato, K; Makino, H; Morita, S; Sugihara, K; Takagi, Y; Uetake, H1
Asuncion, L; Csiszar, K; Dietzsch, E; Fong, KS; Fong, SF; He, Q; Hollosi, P; Parker, MI1
Kang, HJ; Kim, H; Kim, NK; Koh, KH; Rhee, H; Yang, E1
Chang, CK; Chang, HC; Cho, CY; Hung, WC; Wang, JH1
Fuks, F; Griffioen, AW; Hellebrekers, DM; Herman, JG; Langenkamp, E; Melotte, V; Molema, G; Van Criekinge, W; van Engeland, M; Viré, E1
Luo, J; Qi, J; Tao, WH; Zhang, JM; Zhu, YQ1
Glazer, RI; Knode, MC1
Ben-Baruch, N; Cowan, KH; Denicoff, AM; Goldspiel, BR; O'Shaughnessy, JA1
Côté, S; Momparler, RL2
Côté, S; Momparler, RL; Sinnett, D1
Nakamura, N; Takenaga, K1
Fu, Y; Guan, RJ; Holt, PR; Pardee, AB1
Albertsen, H; Dalley, BK; Jones, DA; Karpf, AR; Peterson, PW; Rawlins, JT; Yang, Q1
Bender, CM; Gonzales, FA; Jones, PA; Liang, G; Markl, ID; Salem, CE1
Ammanamanchi, S; Brattain, MG; Periyasamy, S; Tillekeratne, MP1
Brown, R; Kaye, SB; Plumb, JA; Sludden, J; Strathdee, G1
Jones, DA; Karpf, AR; Moore, BC; Ririe, TO1
Magdinier, F; Wolffe, AP1
Ammanamanchi, S; Brattain, MG1
Casey, G; Kasturi, L; Krumroy, L; Li, H; Markowitz, S; Myeroff, L; Schwartz, S; Stanbridge, E; Willson, JK1
Elliott, MS; Gündüz, U; Houghton, JA; Houghton, PJ; Katze, JR; Seubert, PH; Trewyn, RW1
Allegra, CJ; Grem, JL1
Ahluwalia, GS; Arnold, ST; Balzarini, J; Cohen, MB; Cooney, DA; Dalal, M; Johns, DG; Kang, GJ; McMahon, JB; Wilson, YA1
Arundel, CM; Leith, JT1
Allalouf, D; Friedman, J; Levinsky, H; Seger, M1
Cohen, MB; Glazer, RI1

Trials

1 trial(s) available for azacitidine and Colonic Neoplasms

ArticleYear
Phase II study of fazarabine (NSC 281272) in patients with metastatic colon cancer.
    Investigational new drugs, 1993, Volume: 11, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Azacitidine; Colonic Neoplasms; Drugs, Investigational; Female; Humans; Infusions, Intravenous; Male; Middle Aged

1993

Other Studies

86 other study(ies) available for azacitidine and Colonic Neoplasms

ArticleYear
Effect of 5-azacytidine (5-aza) on UCP2 expression in human liver and colon cancer cells.
    International journal of medical sciences, 2021, Volume: 18, Issue:10

    Topics: Azacitidine; Colonic Neoplasms; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; HT29 Cells; Humans; Liver Neoplasms; Promoter Regions, Genetic; Uncoupling Protein 2

2021
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
    Oncotarget, 2017, Jul-11, Volume: 8, Issue:28

    Topics: Animals; Azacitidine; Carcinogenesis; Cell Movement; Cell Proliferation; Colonic Neoplasms; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Staging; RNA, Small Interfering; Tumor Suppressor Proteins; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2017
Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells.
    Drug metabolism and pharmacokinetics, 2017, Volume: 32, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Camptothecin; Colonic Neoplasms; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Etoposide; Gemcitabine; HCT116 Cells; Humans; Irinotecan; Phosphorylation

2017
Epigenetic inactivation of HOXD10 is associated with human colon cancer via inhibiting the RHOC/AKT/MAPK signaling pathway.
    Cell communication and signaling : CCS, 2019, 01-25, Volume: 17, Issue:1

    Topics: Apoptosis; Azacitidine; Cell Movement; Cell Proliferation; Colonic Neoplasms; CpG Islands; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome, Human; Genomic Imprinting; Homeodomain Proteins; Humans; MAP Kinase Signaling System; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; rhoC GTP-Binding Protein; RNA, Messenger; Transcription Factors

2019
Parallel comparison of Illumina RNA-Seq and Affymetrix microarray platforms on transcriptomic profiles generated from 5-aza-deoxy-cytidine treated HT-29 colon cancer cells and simulated datasets.
    BMC bioinformatics, 2013, Volume: 14 Suppl 9

    Topics: Algorithms; Azacitidine; Colonic Neoplasms; Gene Expression Profiling; HT29 Cells; Humans; Oligonucleotide Array Sequence Analysis; Regression Analysis; RNA, Neoplasm; Sensitivity and Specificity; Sequence Analysis, RNA

2013
Different effects of epigenetic modifiers on the cytotoxicity induced by 5-fluorouracil, irinotecan or oxaliplatin in colon cancer cells.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA; DNA Modification Methylases; Drug Synergism; Epigenesis, Genetic; Fluorouracil; HCT116 Cells; Histone Deacetylase Inhibitors; HT29 Cells; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin

2014
Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation.
    Experimental biology and medicine (Maywood, N.J.), 2014, Volume: 239, Issue:3

    Topics: Acetylation; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Bcl-2-Like Protein 11; Butyrates; Cell Line, Tumor; Colonic Neoplasms; Death-Associated Protein Kinases; Decitabine; DNA Methylation; DNA Modification Methylases; Docosahexaenoic Acids; HCT116 Cells; Histones; Humans; Linoleic Acid; Lymphotoxin beta Receptor; Membrane Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Receptors, Tumor Necrosis Factor, Member 25; Transcription, Genetic

2014
Combination of gefitinib and DNA methylation inhibitor decitabine exerts synergistic anti-cancer activity in colon cancer cells.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Synergism; Gefitinib; Humans; Intracellular Signaling Peptides and Proteins; Neoplasm Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; TOR Serine-Threonine Kinases

2014
Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1.
    Cell reports, 2014, Jul-24, Volume: 8, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Cell Hypoxia; Co-Repressor Proteins; Colonic Neoplasms; Decitabine; DNA Modification Methylases; Gene Silencing; HeLa Cells; Histone Demethylases; Humans; MCF-7 Cells; MutL Protein Homolog 1; Nerve Tissue Proteins; Nuclear Proteins

2014
DAC can restore expression of NALP1 to suppress tumor growth in colon cancer.
    Cell death & disease, 2015, Jan-22, Volume: 6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; Azacitidine; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; CpG Islands; Decitabine; Female; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Male; Mice, Nude; Middle Aged; Neoplasm Staging; NLR Proteins; RNA, Messenger; Survival Analysis; Tissue Array Analysis

2015
DNA demethylation caused by 5-Aza-2'-deoxycytidine induces mitotic alterations and aneuploidy.
    Oncotarget, 2016, Jan-26, Volume: 7, Issue:4

    Topics: Aneuploidy; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Cell Proliferation; Chromosome Aberrations; Colonic Neoplasms; Cytogenetic Analysis; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Microscopy, Fluorescence; Mitosis; Ploidies; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2016
Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine.
    Oncotarget, 2016, May-10, Volume: 7, Issue:19

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Computational Biology; Decitabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomics; HCT116 Cells; HT29 Cells; Humans

2016
CD80 down-regulation is associated to aberrant DNA methylation in non-inflammatory colon carcinogenesis.
    BMC cancer, 2016, 07-04, Volume: 16

    Topics: Aged; Azacitidine; B7-1 Antigen; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Male; Middle Aged; Promoter Regions, Genetic

2016
The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry.
    Clinical epigenetics, 2017, Volume: 9

    Topics: Antineoplastic Agents; Azacitidine; Azetidines; Cell Proliferation; Cell Survival; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Dose-Response Relationship, Drug; Down-Regulation; Endogenous Retroviruses; Epigenesis, Genetic; HCT116 Cells; Humans; Immunologic Factors; Interferons; Molecular Mimicry; Nitro Compounds; Transcription, Genetic; Viral Envelope Proteins

2017
Diverse repetitive element RNA expression defines epigenetic and immunologic features of colon cancer.
    JCI insight, 2017, 02-09, Volume: 2, Issue:3

    Topics: Aged; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid; Sequence Analysis, RNA

2017
Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy.
    BMC gastroenterology, 2008, Aug-01, Volume: 8

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Histones; Humans; Hydroxamic Acids; RNA, Messenger; Sequence Analysis, DNA; Stomach Neoplasms

2008
Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma.
    Genes, chromosomes & cancer, 2009, Volume: 48, Issue:1

    Topics: Azacitidine; Carrier Proteins; Cell Line, Tumor; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Expression Profiling; Gene Silencing; Genes, Tumor Suppressor; Glioma; Heat-Shock Proteins; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Melanoma; Membrane Proteins; Microfilament Proteins; Neuropeptides; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Phosphoprotein Phosphatases; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction

2009
Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells.
    International journal of oncology, 2008, Volume: 33, Issue:4

    Topics: Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Decitabine; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, p16; Histone Deacetylase Inhibitors; Humans; Hydroxylamines; Promoter Regions, Genetic; Quinolines

2008
Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro.
    Cancer biology & therapy, 2008, Volume: 7, Issue:12

    Topics: Azacitidine; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Decitabine; DNA; DNA Methylation; G1 Phase; Humans; Insulin-Like Growth Factor Binding Proteins; Neoplasm Invasiveness; RNA, Messenger; Transcription, Genetic

2008
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.
    Carcinogenesis, 2009, Volume: 30, Issue:6

    Topics: Azacitidine; Cell Line, Tumor; Chromosomes, Human, Pair 18; Colonic Neoplasms; CpG Islands; DCC Receptor; Decitabine; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Hydroxamic Acids; Oxidoreductases, N-Demethylating; Promoter Regions, Genetic; Receptors, Cell Surface; Tumor Suppressor Proteins

2009
A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.
    Cancer research, 2009, May-15, Volume: 69, Issue:10

    Topics: Animals; Azacitidine; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Modification Methylases; Female; Gene Silencing; Genes, Tumor Suppressor; HeLa Cells; Humans; Liver Neoplasms; Mice; Quinolines; Reverse Transcriptase Polymerase Chain Reaction

2009
Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells.
    Archives of medical research, 2009, Volume: 40, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Butyrates; Colonic Neoplasms; Decitabine; Enzyme Inhibitors; HT29 Cells; Humans; Hydroxamic Acids; Nuclear Proteins; Receptors, Glucocorticoid; RNA-Binding Proteins; Serine-Arginine Splicing Factors

2009
DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells.
    Journal of cancer research and clinical oncology, 2009, Volume: 135, Issue:12

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Caco-2 Cells; Colonic Neoplasms; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Interleukin-4; Phenotype; Protein Tyrosine Phosphatase, Non-Receptor Type 6; STAT6 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins

2009
Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter.
    Genomics, 2009, Volume: 94, Issue:6

    Topics: Azacitidine; Breast; Breast Neoplasms; Cell Line, Tumor; Cells, Cultured; Colonic Neoplasms; DNA Methylation; Female; Humans; Long Interspersed Nucleotide Elements; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic

2009
5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats.
    Toxicology letters, 2009, Dec-15, Volume: 191, Issue:2-3

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blood Urea Nitrogen; Blotting, Western; Breast Neoplasms; Cell Nucleus; Cisplatin; Colonic Neoplasms; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Synergism; Drug Therapy, Combination; Female; Histones; Kidney Diseases; Male; Mammary Neoplasms, Experimental; Metallothionein; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley

2009
Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines.
    Cancer research, 2009, Oct-15, Volume: 69, Issue:20

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Colonic Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; RNA, Transfer, Amino Acyl; Tumor Cells, Cultured

2009
[Effect of 5-Aza-CdR on expression and methylation of E-cadherin gene in human colon carcinoma cells].
    Chinese journal of cancer, 2010, Volume: 29, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cadherins; Cell Proliferation; Colonic Neoplasms; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; RNA, Messenger

2010
Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells.
    BMC molecular biology, 2010, Jan-22, Volume: 11

    Topics: Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytidine Triphosphate; DNA Methylation; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; HCT116 Cells; Hepatocyte Nuclear Factor 1; HT29 Cells; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Up-Regulation

2010
Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6.
    Molecular cancer research : MCR, 2010, Volume: 8, Issue:4

    Topics: Azacitidine; Carcinogenicity Tests; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Immunohistochemistry; Inflammation Mediators; Interleukin-6; Neoplasm Metastasis; Promoter Regions, Genetic; Up-Regulation

2010
Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation.
    Cancer research, 2010, Sep-01, Volume: 70, Issue:17

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Chromatin Assembly and Disassembly; Colonic Neoplasms; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Green Fluorescent Proteins; Humans; Transfection; Transgenes

2010
Long-term persistence of acquired resistance to 5-fluorouracil in the colon cancer cell line SW620.
    Experimental cell research, 2010, Nov-15, Volume: 316, Issue:19

    Topics: AC133 Antigen; Antigens, CD; Azacitidine; beta Catenin; Cadherins; Cell Adhesion; Cell Death; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Culture Media, Serum-Free; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Epithelium; Fluorouracil; Glycoproteins; Humans; Hyaluronan Receptors; Inhibitory Concentration 50; Kinetics; Mesoderm; Peptides; Time Factors

2010
5-Aza-2'-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression.
    International journal of cancer, 2011, Nov-01, Volume: 129, Issue:9

    Topics: Azacitidine; Colonic Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Drug Synergism; Gene Expression Regulation; HCT116 Cells; HeLa Cells; Humans; Inflammation Mediators; Interleukin-1; Matrix Metalloproteinase 3; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Transcription Factors; Transcriptional Activation

2011
[Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2010, Volume: 41, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Modification Methylases; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Multidrug Resistance-Associated Proteins; Proto-Oncogene Proteins

2010
Correlation between T-cadherin gene expression and aberrant methylation of T-cadherin promoter in human colon carcinoma cells.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2

    Topics: Azacitidine; Blotting, Western; Cadherins; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2012
Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2011, Volume: 24, Issue:6

    Topics: Adenocarcinoma; Adenoma; Antineoplastic Agents, Alkylating; Azacitidine; Caco-2 Cells; Cell Survival; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression; Gene Silencing; Humans; Hydroxamic Acids; Receptors, Calcium-Sensing; RNA, Messenger; Tissue Array Analysis

2011
Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells.
    BMC cancer, 2011, Feb-22, Volume: 11

    Topics: Azacitidine; Caco-2 Cells; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Cytochrome P-450 CYP3A; Decitabine; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Calcitriol; Receptors, Steroid

2011
Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells.
    Epigenetics, 2011, Sep-01, Volume: 6, Issue:9

    Topics: Azacitidine; Chromatin; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 3; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; HCT116 Cells; Histones; Humans; Hydroxamic Acids; Inhibin-beta Subunits; Jumonji Domain-Containing Histone Demethylases; Time Factors; Transcriptional Activation

2011
5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lung Neoplasms; Osteosarcoma; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-mdm2; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130

2012
Diagnostic and prognostic utility of methylation and protein expression patterns of myopodin in colon cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2012, Volume: 33, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Base Sequence; Biomarkers, Tumor; Colonic Neoplasms; CpG Islands; Disease-Free Survival; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Microfilament Proteins; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction

2012
Different involvement of DNA methylation and histone deacetylation in the expression of solute-carrier transporters in 4 colon cancer cell lines.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:3

    Topics: Azacitidine; Cell Line, Tumor; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Membrane Transport Proteins; Real-Time Polymerase Chain Reaction; RNA, Messenger

2012
Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo.
    Journal of immunology (Baltimore, Md. : 1950), 2012, May-01, Volume: 188, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Adoptive Transfer; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; bcl-X Protein; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colonic Neoplasms; Decitabine; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Membrane Proteins; Mice; Mitochondrial Proteins; Neoplasm Metastasis; Neoplasms, Experimental; Proto-Oncogene Proteins; Tumor Escape; Vorinostat

2012
Silencing of Wnt5a during colon cancer metastasis involves histone modifications.
    Epigenetics, 2012, Jun-01, Volume: 7, Issue:6

    Topics: Azacitidine; Cell Line, Tumor; Colonic Neoplasms; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Neoplasm Metastasis; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Wnt Proteins; Wnt-5a Protein

2012
Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells.
    The Journal of steroid biochemistry and molecular biology, 2013, Volume: 136

    Topics: Azacitidine; Caco-2 Cells; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; HT29 Cells; Humans; Steroid Hydroxylases; Vitamin D3 24-Hydroxylase

2013
Characterization of the conversion between CD133+ and CD133- cells in colon cancer SW620 cell line.
    Cancer biology & therapy, 2012, Volume: 13, Issue:14

    Topics: AC133 Antigen; Animals; Antigens, CD; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; Peptides; Reactive Oxygen Species; Transplantation, Heterologous

2012
Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Feb-01, Volume: 19, Issue:3

    Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Humans; Indoles; Methylation; Mice; Mitogen-Activated Protein Kinases; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Sulfonamides; Vemurafenib

2013
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers.
    Cancer genetics and cytogenetics, 2003, Jan-15, Volume: 140, Issue:2

    Topics: Adenocarcinoma; Azacitidine; Base Sequence; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; GTPase-Activating Proteins; Humans; Liver Neoplasms; Male; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Promoter Regions, Genetic; Prostatic Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins

2003
Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma.
    Cell death and differentiation, 2003, Volume: 10, Issue:2

    Topics: Apoptosis; Azacitidine; Caco-2 Cells; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Enhancer Elements, Genetic; fas Receptor; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Promoter Regions, Genetic; Sensitivity and Specificity

2003
SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Jul-08, Volume: 100, Issue:14

    Topics: Adenocarcinoma; Adenoma; Azacitidine; Base Sequence; Cation Transport Proteins; Colonic Neoplasms; DNA Methylation; DNA, Neoplasm; Exons; Gene Silencing; Genes, Tumor Suppressor; Humans; Intestinal Mucosa; Ion Transport; Molecular Sequence Data; Monocarboxylic Acid Transporters; Recombinant Fusion Proteins; Sodium; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay

2003
Silencing of CDX2 expression in colon cancer via a dominant repression pathway.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Adenoma; Azacitidine; Blotting, Western; CDX2 Transcription Factor; Cell Division; Colonic Neoplasms; Cytoplasm; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Homeodomain Proteins; Humans; Hydroxamic Acids; Immunohistochemistry; Methyltransferases; Mutation; Mutation, Missense; Phenotype; Phosphatidylinositol 3-Kinases; Rectal Neoplasms; Trans-Activators; Transcription, Genetic

2003
Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells.
    Oncogene, 2003, Oct-16, Volume: 22, Issue:46

    Topics: Azacitidine; Cell Aggregation; Cell Culture Techniques; Cell Movement; Cell Transformation, Neoplastic; Colonic Neoplasms; Decitabine; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Intestinal Mucosa; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

2003
Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:3

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Colonic Neoplasms; Culture Media, Serum-Free; Decitabine; DNA Methylation; DNA Primers; ErbB Receptors; Folic Acid; Humans; Luciferases; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tetrahydrofolates; Transfection

2004
Epigenetic modification regulates both expression of tumor-associated genes and cell cycle progressing in human colon cancer cell lines: Colo-320 and SW1116.
    Cell research, 2004, Volume: 14, Issue:3

    Topics: Acetylation; Azacitidine; Butyrates; Cell Cycle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Decitabine; DNA; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, APC; Genes, p16; Histones; Humans; Hydroxamic Acids

2004
DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon.
    Cancer letters, 2004, Aug-30, Volume: 212, Issue:2

    Topics: Animals; Azacitidine; Carcinogens; Chenodeoxycholic Acid; Cholic Acid; Colon; Colonic Neoplasms; Decitabine; Deoxycholic Acid; DNA; DNA Methylation; Dose-Response Relationship, Drug; Female; Lithocholic Acid; Male; Mice; Rats; Rats, Inbred F344; Rutin; Time Factors

2004
Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines.
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:11

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Female; Humans; Male; Nerve Tissue Proteins; Prostatic Neoplasms; RNA, Messenger; Stomach Neoplasms

2004
Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines.
    International journal of oncology, 2005, Volume: 26, Issue:4

    Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma; Carcinoma, Renal Cell; Colonic Neoplasms; Decitabine; DNA Methylation; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Isoenzymes; Kidney Neoplasms; Promoter Regions, Genetic; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2005
Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.
    Biochemical and biophysical research communications, 2006, Mar-10, Volume: 341, Issue:2

    Topics: Adrenal Gland Neoplasms; Animals; Arachidonic Acid; Azacitidine; Blotting, Western; Catalysis; Cell Line; Cell Line, Tumor; Cloning, Molecular; Colon; Colonic Neoplasms; CpG Islands; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Decitabine; DNA Methylation; Exons; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Introns; Mixed Function Oxygenases; Protein Folding; Protein Isoforms; Rats; RNA, Messenger; Transfection

2006
Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:2

    Topics: Azacitidine; Biomarkers; Cell Line; Chronic Disease; Colitis, Ulcerative; Colonic Neoplasms; Colonic Polyps; Decitabine; Humans; Hydroxamic Acids; Methylation; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trans-Activators

2006
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.
    Gastroenterology, 2006, Volume: 131, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Neoplasm Proteins; Promoter Regions, Genetic; Protein Synthesis Inhibitors; RNA, Messenger; Stomach Neoplasms

2006
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.
    PLoS medicine, 2006, Volume: 3, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Cathepsin K; Cathepsins; Colonic Neoplasms; CpG Islands; Cyclin A; Cyclin A1; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Profiling; Humans; Lung Neoplasms; Male; Middle Aged; MSX1 Transcription Factor; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Transcription Factors; Tumor Cells, Cultured

2006
Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.
    Annals of surgical oncology, 2007, Volume: 14, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Camptothecin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Irinotecan; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Suppressor Protein p14ARF

2007
Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression.
    The Journal of pathology, 2007, Volume: 212, Issue:1

    Topics: Azacitidine; Cell Line, Tumor; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression; Humans; Immunohistochemistry; Insulin-Like Growth Factor Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction

2007
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.
    Genes, chromosomes & cancer, 2007, Volume: 46, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Oxidoreductases; Azacitidine; Blotting, Western; Cell Differentiation; Cell Line; Colonic Neoplasms; CpG Islands; Decitabine; DNA Primers; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Loss of Heterozygosity; Male; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction

2007
Frequent inactivation of SPARC by promoter hypermethylation in colon cancers.
    International journal of cancer, 2007, Aug-01, Volume: 121, Issue:3

    Topics: Azacitidine; Cell Line, Tumor; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotide Array Sequence Analysis; Osteonectin; Prognosis; Promoter Regions, Genetic; Survival Analysis

2007
Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells.
    Journal of cellular physiology, 2007, Volume: 213, Issue:1

    Topics: Azacitidine; Base Sequence; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Primers; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; GPI-Linked Proteins; Humans; In Vitro Techniques; Membrane Glycoproteins; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm

2007
Identification of epigenetically silenced genes in tumor endothelial cells.
    Cancer research, 2007, May-01, Volume: 67, Issue:9

    Topics: Azacitidine; Caco-2 Cells; Clusterin; Colonic Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Endothelial Cells; Epigenesis, Genetic; Fibrillin-1; Fibrillins; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Microfilament Proteins; Neovascularization, Pathologic; Oxidoreductases Acting on Sulfur Group Donors; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Thioredoxins

2007
[Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenoma; Adult; Aged; Azacitidine; Biomarkers, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Eye Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; HCT116 Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Male; Membrane Proteins; Middle Aged; RNA, Messenger

2007
1-beta-D-arabinosyl-5-azacytosine. Cytocidal activity and effects on the synthesis and methylation of DNA in human colon carcinoma cells.
    Molecular pharmacology, 1984, Volume: 26, Issue:2

    Topics: Azacitidine; Cell Line; Cell Survival; Colonic Neoplasms; DNA, Neoplasm; Humans; Kinetics; Methylation; Stereoisomerism

1984
Evaluation of the antineoplastic activity of adozelesin alone and in combination with 5-aza-2'-deoxycytidine and cytosine arabinoside on DLD-1 human colon carcinoma cells.
    Anti-cancer drugs, 1993, Volume: 4, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzofurans; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Cyclohexanecarboxylic Acids; Cyclohexenes; Cytarabine; Decitabine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Duocarmycins; Humans; Indoles; Lung Neoplasms; Time Factors; Tumor Cells, Cultured

1993
Activation of the retinoic acid receptor beta gene by 5-aza-2'-deoxycytidine in human DLD-1 colon carcinoma cells.
    Anti-cancer drugs, 1997, Volume: 8, Issue:1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blotting, Northern; Blotting, Southern; Cell Line; Colonic Neoplasms; Decitabine; DNA Methylation; Exons; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Receptors, Retinoic Acid; Tretinoin; Tumor Stem Cell Assay

1997
Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells.
    Anti-cancer drugs, 1998, Volume: 9, Issue:9

    Topics: 5-Methylcytosine; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tumor Cells, Cultured

1998
Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:5

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Colonic Neoplasms; Decitabine; DNA Methylation; Gene Expression Regulation; HT29 Cells; Humans; Neoplasm Metastasis; S100 Calcium-Binding Protein A4; S100 Proteins; Transcriptional Activation; Tumor Cells, Cultured

1998
Association of K-ras mutations with p16 methylation in human colon cancer.
    Gastroenterology, 1999, Volume: 116, Issue:5

    Topics: Azacitidine; Cells, Cultured; Colonic Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; Enzyme Inhibitors; Genes, p16; Genes, ras; Humans; Mutation; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

1999
Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Nov-23, Volume: 96, Issue:24

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Cell Division; Cell Nucleus; Colonic Neoplasms; Decitabine; DNA Modification Methylases; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Interferon alpha-2; Interferon-alpha; Interferon-beta; Interferon-gamma; Interferons; Recombinant Proteins; Signal Transduction; STAT1 Transcription Factor; STAT2 Transcription Factor; STAT3 Transcription Factor; Trans-Activators

1999
PAX6 methylation and ectopic expression in human tumor cells.
    International journal of cancer, 2000, Jul-15, Volume: 87, Issue:2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Exons; Eye Proteins; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Paired Box Transcription Factors; PAX6 Transcription Factor; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2000
Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency.
    Oncogene, 2000, Sep-21, Volume: 19, Issue:40

    Topics: Activin Receptors, Type I; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Colonic Neoplasms; Cyclin A; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Sp1 Transcription Factor; Transcriptional Activation; Transfection; Tumor Cells, Cultured

2000
Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter.
    Cancer research, 2000, Nov-01, Volume: 60, Issue:21

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Base Pair Mismatch; Carboplatin; Carrier Proteins; Cisplatin; Colonic Neoplasms; Dacarbazine; Decitabine; DNA Methylation; DNA Repair; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2000
Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.
    Molecular pharmacology, 2001, Volume: 59, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Survival; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Decitabine; DNA Damage; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; G1 Phase; Gene Expression Regulation; HT29 Cells; Humans; Mutation; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2001
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Apr-24, Volume: 98, Issue:9

    Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Chromatin; Colonic Neoplasms; CpG Islands; Cross-Linking Reagents; DNA; DNA Methylation; DNA-Binding Proteins; Formaldehyde; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, p16; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Models, Genetic; Promoter Regions, Genetic; Protein Binding; Proteins; RNA, Messenger; Substrate Specificity; Transcriptional Activation; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF

2001
5-azaC treatment enhances expression of transforming growth factor-beta receptors through down-regulation of Sp3.
    The Journal of biological chemistry, 2001, Aug-31, Volume: 276, Issue:35

    Topics: Activin Receptors, Type I; Azacitidine; Breast Neoplasms; Cell Nucleus; Colonic Neoplasms; DNA-Binding Proteins; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sp3 Transcription Factor; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2001
Chromosomal autonomy of hMLH1 methylation in colon cancer.
    Oncogene, 2002, Feb-21, Volume: 21, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Alleles; Azacitidine; Blotting, Western; Carrier Proteins; Chromosomes, Human, Pair 3; Colonic Neoplasms; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Hybrid Cells; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2002
Absence of tRNA-guanine transglycosylase in a human colon adenocarcinoma cell line.
    Biochimica et biophysica acta, 1992, Jul-07, Volume: 1139, Issue:3

    Topics: Adenocarcinoma; Animals; Azacitidine; Cell Cycle; Colonic Neoplasms; Guanine; Humans; Mice; Mutation; Neoplasm Transplantation; Pentosyltransferases; Rhabdomyosarcoma; RNA Processing, Post-Transcriptional; RNA, Transfer; Tumor Cells, Cultured

1992
Sequence-dependent interaction of 5-fluorouracil and arabinosyl-5-azacytosine or 1-beta-D-arabinofuranosylcytosine.
    Biochemical pharmacology, 1991, Jul-05, Volume: 42, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Colonic Neoplasms; Cytarabine; Cytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Nucleic Acids; Thymine Nucleotides; Tumor Stem Cell Assay

1991
Arabinosyl-5-azacytosine: mechanisms of native and acquired resistance.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: Animals; Azacitidine; Biological Transport; Colonic Neoplasms; Cytidine; Deoxycytidine; Deoxycytidine Kinase; DNA; Drug Resistance; Humans; Leukemia P388; Mice; Phosphorylation

1986
Effects of nucleoside analogs and sodium butyrate on recovery from potentially lethal X ray damage in human colon tumor cells.
    International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Butyrates; Butyric Acid; Cells, Cultured; Colon; Colonic Neoplasms; Decitabine; Humans; Radiation-Sensitizing Agents

1987
Modulation of carcinoembryonic antigen release by HT-29 colon carcinoma line in the presence of different agents.
    Experientia, 1987, Oct-15, Volume: 43, Issue:10

    Topics: Acetamides; Azacitidine; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Differentiation; Colonic Neoplasms; Drug Synergism; Formamides; Humans; Tetradecanoylphorbol Acetate; Tretinoin

1987
Cytotoxicity and the inhibition of ribosomal RNA processing in human colon carcinoma cells.
    Molecular pharmacology, 1985, Volume: 27, Issue:2

    Topics: Azacitidine; Azaguanine; Cell Survival; Cells, Cultured; Colonic Neoplasms; Fluorouracil; Humans; Protein Biosynthesis; Pyrimidine Nucleosides; RNA, Ribosomal; Toyocamycin; Tubercidin

1985