Compounds > azacitidine

azacitidine and Chromosomal Translocation

azacitidine has been researched along with Chromosomal Translocation in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19905 (19.23)18.7374
1990's2 (7.69)18.2507
2000's9 (34.62)29.6817
2010's9 (34.62)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Dhangar, S; Ghatanatti, J; Mathan S, LP; Sawant, L; Shah, A; Shanmukhaiah, C; Vundinti, BR1
Borthakur, G; Cortes, J; Daver, N; Ferrajoli, A; Garcia-Manero, G; Kadia, T; Kantarjian, HM; Ohanian, M; Oran, B; Pemmaraju, N; Ragon, BK; Ravandi, F1
Nohgawa, M; Oka, S; Ono, K1
Iliakis, G; Moscariello, M1
Jaksic, O; Kusec, R; Lasan-Trcic, R; Lucijanic, M; Pejsa, V; Stoos-Veic, T1
Fujii, S; Fujita, M; Iyama, S; Jomen, W; Kanari, Y; Kato, J; Kuroda, H; Maeda, M; Sato, M; Shimoyama, S; Usami, M; Yamada, M; Yoshida, M1
Ando, T; Kimura, S; Kizuka, H; Kojima, K; Kubota, Y; Kusaba, K; Nishioka, A; Sano, H; Shindo, T; Ureshino, H1
Dirks, WG; Drexler, HG; Marschalek, R; Meyer, C; Quentmeier, H; Röhrs, S; Scherr, M; Slany, R; Wallace, A1
Balgobind, BV; Baruchel, A; Cloos, J; Coenen, EA; Danen-van Oorschot, AA; de Bont, ES; de Haas, V; den Boer, ML; Kaspers, GJ; Kuipers, JE; Marschalek, R; Meyer, C; Pieters, R; Reinhardt, D; Stary, J; van den Heuvel-Eibrink, MM; Zwaan, CM1
Camós, M; Colomer, D; Díaz, T; Díaz-Beyá, M; Esteve, J; Ferrer, G; Gel, B; Monzo, M; Navarro, A; Pratcorona, M; Rozman, M; Torrebadell, M1
Guan, H; Klapproth, K; Ushmorov, A; Weitzer, CD; Wirth, T; Xie, L1
Facchinetti, F; Mezzanzanica, D; Modena, P; Pilotti, S; Radice, MT; Sozzi, G; Testi, MA1
Buffler, PA; Gunn, L; Leung, K; Ma, X; Smith, MT; Wiemels, JL; Wiencke, JK; Zhang, L; Zheng, S1
Gozzini, A; Santini, V1
Andreeff, M; Contractor, R; Issa, JP; Jin, L; Kondo, Y; Konopleva, M; Miyake, K; Miyake, N; Nagaoka, I; Ohsaka, A; Ruvolo, V; Tabe, Y; Tsutsumi-Ishii, Y1
Callet-Bauchu, E; Emura, M; Groenen, P; Kamphues, K; Lehmann, U; Ripperger, T; Rudolph, C; Schlegelberger, B; Schraders, M; Skawran, B; Steinemann, D; Tauscher, M; van Krieken, JH; von Neuhoff, N1
Aventín, A; Brunet, S; Carnicer, MJ; Lasa, A; Nomdedéu, JF; Orantes, V; Pena, J; Serrano, E; Sierra, J1
Golomb, HM; Larson, RA; Rowley, JD; Sweet, DL; Testa, JR1
Brouet, JC; Dellagi, K; Lenoir, GM; Portier, MM1
Campos, A; Fernández, JL; Goyanes, V; Pereira, S1
Hagemeijer, A; Hoebee, B; Honders, MW; Landegent, JE; Stegmann, AP; Willemze, R1
Camitta, B; Carroll, AJ; Chang, M; Gresik, MV; Raimondi, SC; Ravindranath, Y; Steuber, CP; Weinstein, H1
Ding, BC; Heng, H; Hukku, B; Matherly, LH; Witt, TL; Zhang, L1
Applegate, ML; Hozier, JC; Moore, MM1
Haaf, T; Schmid, M1
Haaf, T; Schindler, D; Schmid, M1

Reviews

1 review(s) available for azacitidine and Chromosomal Translocation

ArticleYear
5q- syndrome-like features as the first manifestation of myelodysplastic syndrome in a patient with an unbalanced whole-arm translocation der(5;19)(p10;q10).
    International journal of hematology, 2017, Volume: 105, Issue:5

    Topics: Anemia, Macrocytic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 5; Fatal Outcome; Female; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Thalidomide; Translocation, Genetic

2017

Trials

1 trial(s) available for azacitidine and Chromosomal Translocation

ArticleYear
Minimal residual disease eradication with epigenetic therapy in core binding factor acute myeloid leukemia.
    American journal of hematology, 2017, Volume: 92, Issue:9

    Topics: Adult; Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Decitabine; Disease-Free Survival; Epigenesis, Genetic; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm, Residual; Survival Rate; Translocation, Genetic; Vidarabine

2017

Other Studies

24 other study(ies) available for azacitidine and Chromosomal Translocation

ArticleYear
Synergetic effect of Azacitidine and Sorafenib in treatment of a case of myeloid neoplasm with sole chromosomal abnormality t(8;22)(p11.2;q11.2)/BCR-FGFR1 rearrangement.
    Cancer genetics, 2023, Volume: 274-275

    Topics: Azacitidine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myeloproliferative Disorders; Receptor, Fibroblast Growth Factor, Type 1; Sorafenib; Translocation, Genetic

2023
Successful treatment with azacitidine for the simultaneous occurrence of multiple myeloma and acute myeloid leukemia with concomitant del(5q) and the JAK2 V617F mutation.
    Annals of hematology, 2017, Volume: 96, Issue:8

    Topics: Aged; Anemia, Macrocytic; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 5; Disease Progression; Female; Humans; In Situ Hybridization, Fluorescence; Janus Kinase 2; Leukemia, Myeloid, Acute; Multiple Myeloma; Mutation, Missense; Neoplasms, Multiple Primary; Remission Induction; Translocation, Genetic

2017
Effects of chromatin decondensation on alternative NHEJ.
    DNA repair, 2013, Volume: 12, Issue:11

    Topics: Animals; Azacitidine; Cell Cycle; Cell Line; Chromatin; Chromosomal Instability; Cytosine; Decitabine; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA Ligases; DNA Methylation; Gene Expression Regulation; Humans; Hypotonic Solutions; Mice; Translocation, Genetic

2013
Loss of response to azacitidine is associated with deletion 12p13 in a patient with myelodysplastic syndrome with unique translocation t(13;17)(q12;q25) after prior breast cancer and acute promyelocytic leukemia.
    Annals of hematology, 2015, Volume: 94, Issue:9

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 13; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Translocation, Genetic

2015
[Successful Hematopoietic Cell Transplantation Following Azacitidine Treatment in an Acute Myeloid Leukemia Patient with t(3;3)(q21;q26.2) Translocation and Marked Thrombocythemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:8

    Topics: Adult; Antimetabolites, Antineoplastic; Azacitidine; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Translocation, Genetic

2015
Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia.
    Molecular cancer, 2009, Oct-16, Volume: 8

    Topics: Azacitidine; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Leukemic; Histones; Humans; Hydroxamic Acids; Immunoglobulins; Leukemia, Myeloid, Acute; Membrane Proteins; Mutation; Myeloid-Lymphoid Leukemia Protein; Nerve Tissue Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; Sequence Analysis, DNA; Tissue Inhibitor of Metalloproteinase-3; Transcription, Genetic; Translocation, Genetic; Tumor Suppressor Proteins

2009
High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).
    Blood, 2011, Jan-20, Volume: 117, Issue:3

    Topics: Adolescent; Azacitidine; Blotting, Western; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Cell Line, Tumor; Child; Child, Preschool; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Immunoglobulins; Infant; Infant, Newborn; Leukemia, Monocytic, Acute; Male; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Survival Analysis; Translocation, Genetic

2011
Acute myeloid leukemia with translocation (8;16)(p11;p13) and MYST3-CREBBP rearrangement harbors a distinctive microRNA signature targeting RET proto-oncogene.
    Leukemia, 2013, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 8; Cluster Analysis; CREB-Binding Protein; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Rearrangement; Histone Acetyltransferases; Humans; Leukemia, Myeloid, Acute; Male; MicroRNAs; Middle Aged; Oligonucleotide Array Sequence Analysis; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Prognosis; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Translocation, Genetic; Tumor Cells, Cultured; Young Adult

2013
Decitabine represses translocated MYC oncogene in Burkitt lymphoma.
    The Journal of pathology, 2013, Volume: 229, Issue:5

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Modification Methylases; Dose-Response Relationship, Drug; Epigenetic Repression; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulin M; Inhibitor of Differentiation Protein 2; NF-kappa B; Proto-Oncogene Proteins c-myc; Transcription, Genetic; Transfection; Translocation, Genetic; Up-Regulation

2013
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.
    Oncogene, 2003, Jul-17, Volume: 22, Issue:29

    Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 22; CpG Islands; DNA Methylation; DNA-Binding Proteins; Electron Transport Complex III; Exons; Extrachromosomal Inheritance; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Kruppel-Like Transcription Factors; Molecular Sequence Data; Neoplasm Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Proteins; Repressor Proteins; RNA-Binding Protein EWS; Sarcoma; Soft Tissue Neoplasms; Translocation, Genetic; Tumor Cells, Cultured

2003
Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia.
    Cancer research, 2004, Mar-15, Volume: 64, Issue:6

    Topics: Acid Anhydride Hydrolases; Adolescent; Antimetabolites, Antineoplastic; Azacitidine; B-Lymphocytes; Child; Child, Preschool; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 21; CpG Islands; Decitabine; Diploidy; DNA Methylation; DNA, Neoplasm; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid; Male; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; T-Lymphocytes; Translocation, Genetic; Tumor Cells, Cultured

2004
Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts.
    Annals of hematology, 2005, Volume: 84 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Butyrates; Cell Differentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Decitabine; DNA Modification Methylases; Epigenesis, Genetic; Gene Silencing; Granulocytes; Histone Deacetylase Inhibitors; Humans; Leukemia, Myeloid, Acute; Mannose; Translocation, Genetic

2005
PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
    Annals of hematology, 2006, Volume: 85, Issue:10

    Topics: Antineoplastic Agents; Azacitidine; Core Binding Factor Alpha 2 Subunit; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Histone Deacetylases; HL-60 Cells; Humans; K562 Cells; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; RNA, Messenger; RNA, Neoplasm; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic; Tretinoin; U937 Cells

2006
Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas.
    Haematologica, 2007, Volume: 92, Issue:4

    Topics: Azacitidine; Cell Line, Tumor; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 14; Decitabine; Disease Progression; DNA Methylation; DNA, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; GTPase-Activating Proteins; Humans; Lymphoma, Mantle-Cell; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Promoter Regions, Genetic; Transcription, Genetic; Translocation, Genetic

2007
Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias.
    Leukemia research, 2008, Volume: 32, Issue:6

    Topics: Adult; Azacitidine; Biomarkers, Tumor; Chromatin Assembly and Disassembly; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Core Binding Factor Alpha 2 Subunit; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Mutation; Oligonucleotide Array Sequence Analysis; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic; Tumor Cells, Cultured; U937 Cells

2008
Response to 5-azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings.
    Cancer, 1982, Jun-01, Volume: 49, Issue:11

    Topics: Adult; Azacitidine; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Female; Follow-Up Studies; Humans; Karyotyping; Leukemia, Lymphoid; Male; Middle Aged; Translocation, Genetic

1982
Abnormal expression of vimentin intermediate filaments in human lymphoid cell lines with deletion or translocation of the distal end of chromosome 8.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:1

    Topics: Azacitidine; Burkitt Lymphoma; Cell Line; Chromosome Deletion; Chromosomes, Human, 6-12 and X; Fluorescent Antibody Technique; Humans; Intermediate Filament Proteins; Lymphocytes; Translocation, Genetic; Vimentin

1984
Assessment of Yqh translocations.
    Journal of medical genetics, 1994, Volume: 31, Issue:12

    Topics: Azacitidine; Chromosomes, Human, Pair 21; Female; Humans; In Situ Hybridization, Fluorescence; Male; Microscopy, Electron; Translocation, Genetic; X Chromosome; Y Chromosome

1994
In vitro-induced resistance to the deoxycytidine analogues cytarabine (AraC) and 5-aza-2'-deoxycytidine (DAC) in a rat model for acute myeloid leukemia is mediated by mutations in the deoxycytidine kinase (dck) gene.
    Annals of hematology, 1995, Volume: 71, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Base Sequence; Chromosome Aberrations; Cytarabine; Decitabine; Deoxycytidine Kinase; Drug Resistance; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Molecular Sequence Data; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Translocation, Genetic; Tumor Cells, Cultured

1995
Prognostic factors in children and adolescents with acute myeloid leukemia (excluding children with Down syndrome and acute promyelocytic leukemia): univariate and recursive partitioning analysis of patients treated on Pediatric Oncology Group (POG) Study
    Leukemia, 2000, Volume: 14, Issue:7

    Topics: Adolescent; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cohort Studies; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Life Tables; Male; Multicenter Studies as Topic; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Remission Induction; Risk Assessment; Risk Factors; Survival Analysis; Thioguanine; Translocation, Genetic; Treatment Failure; Treatment Outcome; United States

2000
Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.
    Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

    Topics: 5' Untranslated Regions; Antimetabolites, Antineoplastic; Azacitidine; Biological Transport; Carrier Proteins; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Reporter; Histones; Humans; Hydroxamic Acids; In Situ Hybridization, Fluorescence; K562 Cells; Karyotyping; Leukemia, Erythroblastic, Acute; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Promoter Regions, Genetic; Reduced Folate Carrier Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Translocation, Genetic

2001
Do trifluorothymidine-resistant mutants of L5178Y mouse lymphoma cells re-express thymidine kinase activity following 5-azacytidine treatment?
    Mutation research, 1988, Volume: 207, Issue:2

    Topics: Animals; Azacitidine; Drug Resistance; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Thymidine; Thymidine Kinase; Translocation, Genetic; Trifluridine; Tumor Cells, Cultured

1988
5-Azadeoxycytidine induced undercondensation in the giant X chromosomes of Microtus agrestis.
    Chromosoma, 1989, Volume: 98, Issue:2

    Topics: Animals; Arvicolinae; Azacitidine; Cell Line; Decitabine; DNA Replication; Female; Fibroblasts; Heterochromatin; Karyotyping; Metaphase; Translocation, Genetic; X Chromosome

1989
5-Azacytidine treatments in the characterization of a t(1;21)(q12;q22) carrier karyotype.
    Clinical genetics, 1985, Volume: 27, Issue:1

    Topics: Adult; Azacitidine; Chromosomes, Human, 1-3; Chromosomes, Human, 21-22 and Y; Female; Heterozygote; Humans; Karyotyping; Translocation, Genetic

1985