azacitidine has been researched along with Carcinoma, Epidermoid in 136 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.47) | 18.7374 |
| 1990's | 10 (7.35) | 18.2507 |
| 2000's | 47 (34.56) | 29.6817 |
| 2010's | 75 (55.15) | 24.3611 |
| 2020's | 2 (1.47) | 2.80 |
| Authors | Studies |
|---|---|
| Amirinia, F; Asadi, N; Hodjat, M; Jourshari, PB | 1 |
| Belloni, A; Byrne, HJ; Giorgini, E; Monterubbianesi, R; Notarstefano, V; Orilisi, G; Pro, C; Sabbatini, S; Tosco, V; Vaccari, L | 1 |
| Li, JR; Li, SY; Sun, LL; Yang, SM; Yu, HB | 1 |
| Jayaprakash, C; Radhakrishnan, R; Ray, S; Satyamoorthy, K | 1 |
| Ming, F; Sun, Q | 1 |
| Chen, C; Liu, X; Ma, Z; Yu, Z; Zhang, H | 1 |
| Bai, G; Bao, Y; Chu, J; Eli, M; Wen, H | 1 |
| Bellinger, G; Bhatia, A; Biktasova, A; Burtness, B; Deshpande, HA; Gary, C; Hajek, M; Issaeva, N; Judson, B; Mehra, S; Sewell, A; Yarbrough, WG | 1 |
| da Costa, NM; de Almeida Simão, T; Gonzaga, IM; Herceg, Z; Hernandez-Vargas, H; Nicolau, MC; Nicolau-Neto, P; Ribeiro Pinto, LF; Soares Lima, SC | 1 |
| He, J; Li, Y; Luo, M; Shi, X; Sun, N; Yang, W; Zhou, F | 1 |
| Besse, B; Domine Gomez, M; Fandi, A; Felip, E; Garassino, MC; Garrido, P; Giaccone, G; Levy, BP; MacBeth, KJ; Menezes, D; Paz-Ares, L; Piperdi, B; Ponce-Aix, S; Risueño, A; Slepetis, R; Wu, X | 1 |
| Cheng, Y; Dong, M; Fan, X; Feng, X; Jin, Z; Meltzer, SJ; Mori, Y; Wang, L; Zhang, X; Zhao, Z | 1 |
| Cao, Z; Chen, S; Cheng, Y; Dong, M; Fan, X; Feng, X; Gao, Y; Jin, Z; Liu, J; Meltzer, SJ; Mori, Y; Wang, L; Yu, H; Zhang, X; Zhang, Y; Zhao, Z | 1 |
| Akhtar, J; Chen, HX; Liu, H; Wang, S; Wang, Z | 1 |
| Chen, X; Dong, W; Fan, Q; Huang, L; Li, F; Liu, J; Wang, F; Wang, L; Wang, M; Yue, D; Zhang, B; Zhang, Y; Zhang, Z | 1 |
| Hu, RC; Liu, JJ; Liu, WE; Tan, SX; Tan, YL | 1 |
| Ling, Y; Liu, Y; Lu, M; Xu, Y; Zhang, C; Zhou, T; Zhu, C; Zhu, J | 1 |
| Arroyo-Solera, I; Barnadas, A; Casanova, I; Céspedes, MV; Gallardo, A; León, X; López, M; López-Pousa, A; Mangues, MA; Mangues, R; Pavón, MA; Quer, M; Téllez-Gabriel, M | 1 |
| Shang, ZJ; Shen, H; Song, K; Xia, XY; Zhang, HZ; Zhu, F | 1 |
| Cha, HJ; Chang, HW; Choi, SH; Han, MW; Kim, SA; Kim, SW; Kim, SY; Lee, JC; Lee, WH; Min, YJ | 1 |
| Cui, L; Dong, Z; Guo, W; Guo, Y; Kuang, G; Shen, S; Wang, C | 1 |
| Dong, Z; Guo, W; Guo, Y; Kuang, G; Shen, S; Yang, Z; Zhang, M | 1 |
| Destro, MF; Duarte, CM; Nunes, FD; Xavier, FC | 1 |
| Cao, Z; Chen, S; Cheng, Y; Dong, M; Fan, X; Feng, X; Gao, Y; Jin, Z; Liu, J; Meltzer, SJ; Mori, Y; Wang, L; Wu, W; Yu, H; Zhang, X; Zhao, Z | 1 |
| Campbell, RR; Dang, D; Ono, K; Schmidt, BL; Viet, CT; Ye, Y | 1 |
| Hou, SY; Liu, WH; Sang, MX; Shan, BE; Zhang, C | 1 |
| Gopinath, KS; Kumar, A; Shivananda, S; Tiwari, A | 1 |
| Achdjian, S; Dang, D; Katz, SG; Schmidt, BL; Viet, CT; Ye, Y | 1 |
| Chiyomaru, T; Enokida, H; Goto, Y; Higashimoto, I; Inoue, H; Mataki, H; Matsushita, R; Mizuno, K; Nakagawa, M; Nishikawa, R; Samukawa, T; Seki, N | 1 |
| Dong, Z; Guo, W; Guo, X; Guo, Y; Kuang, G; Shen, S; Wang, C | 1 |
| Kim, EJ; Kim, JS; Kim, SH; Kim, SM; Kim, SY; Lee, M | 1 |
| Ahrens, TD; Boerries, M; Busch, H; Follo, M; Hembach, S; Hoeppner, J; Hopt, UT; Lassmann, S; Ostendorp, J; Timme, S; Werner, M | 1 |
| Hu, R; Huang, Y; Jiang, H; Lu, Y; Sun, Y; Wang, J; Yan, J; Yang, Y; Zhang, Y | 1 |
| Qi, X; Wang, W; Wu, M | 1 |
| Banas, M; Cichy, J; Guzik, K; Koltun, M; Krzykawska-Serda, M; Kwitniewski, M; Majewski, P; Makarska, A; Marczynska, J | 1 |
| Dong, Z; Guo, W; Guo, X; Guo, Y; Kuang, G; Liang, J; Liu, Y; Shen, S | 1 |
| Li, X; Liao, J; Liu, R; Pan, E; Pu, Y; Wang, Y; Yang, M; Yin, L | 1 |
| Cheng, JC; Chiang, MT; Chiu, KC; Chou, YT; Huang, RY; Huang, SM; Lee, CH; Liu, SY; Shieh, YS | 1 |
| Chen, J; Qiu, X; Wang, Z; You, Y; Zhang, Z | 1 |
| Brown, H; Chresta, CM; Delpuech, O; Taylor, MA; Wappett, M | 1 |
| Li, SS; Liu, JJ; Liu, ZH; Yang, XM | 1 |
| Bao, Y; Chen, Z; Dong, H; Guo, Y; Li, K; Shen, K; Wang, Q; Yang, W; Yang, Y; Zhang, H | 1 |
| He, Y; Huang, C; Huang, K; Li, Z; Liu, H; Ye, G; Zhou, X | 1 |
| Baba, H; Baba, Y; Harada, K; Ishimoto, T; Iwatsuki, M; Kiyozumi, Y; Kosumi, K; Kurashige, J; Miyake, K; Nakamura, K; Nakao, M; Ohuchi, M; Sakamoto, Y; Shigaki, H; Watanabe, M; Yoshida, N | 1 |
| Beninati, C; Catalano, T; Teti, D; Venza, I; Venza, M; Visalli, M | 1 |
| Duan, Y; Han, X; Jia, Y; Liu, L; Lv, W; Ma, M; Wang, J; Wang, X; Wang, Y | 1 |
| Chakraborty, S; Gopinath, KS; Kumar, A; Mohiyuddin, SM | 1 |
| Arab, K; Bennett, KL; Claus, R; Dyckhoff, G; Herpel, E; Karpenko, M; Lin, MT; Plass, C; Plinkert, P; Smiraglia, D | 1 |
| Arai, M; Imazeki, F; Mikata, R; Ochiai, T; Sakai, Y; Seki, N; Shimada, H; Tada, M; Yokosuka, O | 1 |
| De Schutter, H; Isebaert, S; Kimpe, M; Nuyts, S | 1 |
| Beder, LB; Fujihara, K; Fukushima, K; Grenman, R; Gunduz, E; Gunduz, M; Hotomi, M; Shimada, J; Shimizu, K; Tamura, S; Yamanaka, N; Yaykasli, K | 1 |
| Claesson, MH; Krishnadath, KK; Milano, F; Pedersen, AW; Weinert, BT; Zocca, MB | 1 |
| De Grazia, G; Loddo, S; Teti, D; Tripodo, B; Venza, I; Venza, M; Visalli, M | 1 |
| Albert, M; Gudas, LJ; Scognamiglio, T; Tang, XH | 1 |
| Brentani, H; Calmon, MF; Camargo, AA; Carraro, DM; Cury, PM; da Silva, AM; de Carvalho, AF; Kaneto, CM; Kowalski, LP; Mota, LD; Moura, RP; Nishimoto, IN; Nunes, FD; Pinheiro, DG; Rahal, P; Rodrigues, RV; Silva, SD; Silva, WA; Soares, FA; Tajara, EH; Torres, C; Valentini, SR; Zanelli, CF | 1 |
| Califano, JA; Chang, SS; Chang, X; Demokan, S; Kim, MS; Monitto, CL; Sidransky, D; Zhong, X | 1 |
| He, Y; Li, P; Wang, J; Wang, Y; Zhang, S; Zhu, S | 1 |
| Brieger, J; Fruth, K; Hedrich, J; Mann, SA; Mann, WJ; Pogozelski, B; Pongsapich, W | 1 |
| Buim, ME; Carvalho, AL; Coutinho-Camillo, CM; de Carvalho, AC; Fregnani, JH; Kowalski, LP; Lessa, RC; Lourenço, SV; Pereira, CM; Soares, FA; Vettore, AL | 1 |
| Li, P; Meng, XY; Wang, YJ; Zhang, ST; Zhu, ST; Zong, Y | 1 |
| Dong, ZM; Fang, XH; Ge, MH; Hu, FJ; Li, P; Ling, ZQ; Mao, WM; Zhao, X | 1 |
| Liu, HG; Liu, Y | 1 |
| Cheong, SC; Gan, CP; Hamid, S; Hor, SY; Ismail, SM; Saunders, N; Teo, SH; Wan Mustafa, WM; Zain, RB | 1 |
| Jiao, Y; Li, P; Meng, Y; Wang, JX; Wang, QG; Zhang, ST; Zhu, ST | 1 |
| Al-Sohaily, S; Cooper, WA; Kennedy, CW; Kohonen-Corish, MR; McCaughan, BC; Mladenova, DN; Pangon, L; Selinger, CI; Stirzaker, C | 1 |
| Hoshino, H; Moriya, Y; Okamoto, T; Suzuki, M; Tamura, H; Yoshida, S; Yoshino, I | 1 |
| Brown, KD; Darst, RP; Delmas, AL; Dyer, LM; Hakam, A; Izumchenko, EG; Kladde, MP; Monroe, M; Pardo, CE; Riggs, BM; Siegel, EM | 1 |
| He, YL; Wang, JX; Yang, S; Zhang, ST; Zhu, ST | 1 |
| Chen, NN; Chen, XY; Fu, YS; Kong, QY; Li, H; Li, Y; Liu, J; Liu, ZL; Wu, ML | 1 |
| Brieger, J; Fruth, K; Koutsimpelas, D; Mann, SA; Mann, WJ; Pongsapich, W | 1 |
| Brieger, J; Heinrich, U; Koutsimpelas, D; Mann, S; Mann, WJ; Pongsapich, W | 1 |
| Bai, T; Kobayashi, A; Matsuoka, T; Sasaki, N; Tanaka, J; Tanaka, T; Tanizaki, Y; Toujima, S; Utsunomiya, H; Utsunomiya, T; Yamamoto, M; Yukawa, K | 1 |
| Bermejo, JL; Campos, B; Chaisaingmongkol, J; Claus, R; Dyckhoff, G; Geiselhart, L; Herold-Mende, C; Herpel, E; Lasitschka, F; Oakes, CC; Plass, C; Popanda, O; Schmezer, P; Warta, R | 1 |
| Han, L; Hou, H; Li, H; Liu, J; Tong, S; Wang, XQ; Yan, Q; Yang, X | 1 |
| Guo, LP; Li, LW; Li, XY; Lu, SX; Yu, XY; Zhou, Y | 1 |
| Cui, YT; Dong, SW; He, Z; Liang, SJ; Liu, YM; Sun, P; Wang, S; Wang, YG; Zhang, P | 1 |
| Cui, YT; Dong, SW; He, Z; Liang, DC; Liang, SJ; Liu, YM; Wang, S; Wang, YG; Zhang, P; Zhong, RR | 1 |
| Li, P; Meng, XY; Wang, YJ; Zhang, ST; Zhou, QZ; Zhu, ST | 1 |
| Chen, XY; Guo, MZ; He, QY | 1 |
| Jones, V; Katiyar, SK; Prasad, R; Singh, T; Vaid, M | 1 |
| Aoki, D; Banno, K; Kisu, I; Kobayashi, Y; Masuda, K; Nomura, H; Susumu, N; Tominaga, E; Tsuji, K; Ueki, A; Yamagami, W; Yanokura, M | 1 |
| Atallah, E; Olasz, E; Randhawa, J; Wong, S | 1 |
| Califano, JA; Demokan, S; Glazer, CA; Hennessey, P; Loyo, M; Mydlarz, W; Ochs, MF; Pattani, KM; Schussel, J; Smith, IM; Soudry, E; Sun, W; Wang, H | 1 |
| Jiang, GY; Li, QC; Wang, EH; Xu, HT; Xu, K; Yang, LH; Zhang, XP; Zhao, HY | 1 |
| Chang, KW; Chiang, WF; Chu, TH; Gong, NR; Lin, SC; Liu, CJ; Wu, CH; Yang, CC | 1 |
| Fukuyama, Y; Gazdar, AF; Minna, JD; Tockman, MS; Toyooka, S; Wistuba, II | 1 |
| Bartram, CR; Imamura, M; Imoto, I; Inazawa, J; Inoue, J; Janssen, JW; Shimada, Y; Ueda, M | 1 |
| Caldas, AP; Campos, O; Cancella, AI; Dal Lago, L; DiLeone, LP; Monego, E; Pohlmann, P; Rivoire, W; Schwartsmann, G | 1 |
| Hoque, MO; Meltzer, SJ; Mori, M; Osada, M; Sato, F; Sidransky, D; Upadhyay, S; Xiao, Y; Yamashita, K | 1 |
| Chan, AW; Chan, MW; Chan, PK; Lee, TL; Lo, KW; To, KF; Tong, JH; Yu, MY | 1 |
| Bukawa, H; Miyakawa, A; Mochida, Y; Nakatsuru, M; Ono, K; Shiiba, M; Tada, A; Tanzawa, H; Uzawa, K; Yokoe, H | 1 |
| Baylin, SB; Belinsky, SA; Crume, KP; Esteller, M; Grimes, MJ; Joste, N; Palmisano, WA; Toyota, M; Winters, SA | 1 |
| Bone, JR; Briggs, KL; Clayman, GL; Coombes, MM; Dent, SY; El-Naggar, AK | 1 |
| Chen, Q; Kramer, RH; Lipkina, G; Song, Q | 1 |
| Amagasa, T; Chin, K; Gray, JW; Hirohashi, S; Imamura, M; Imoto, I; Inazawa, J; Inoue, J; Shibata, T; Shimada, Y; Sonoda, I | 1 |
| Chen, Y; Deutschmann, N; Hühn, D; Knösel, T; Pacyna-Gengelbach, M; Petersen, I | 1 |
| Kawasaki, K; Moriya, T; Shiiba, M; Shimada, K; Tada, A; Tanzawa, H; Uesugi, H; Uzawa, K | 1 |
| Choi, EJ; Kim, JS; Kim, YH; Seo, JH; Whang, YM; Yoo, YD | 1 |
| Guo, C; Kong, WJ; Wang, Y; Zhang, D; Zhang, S | 1 |
| Chen, D; Christman, JK; Fang, MZ; Jin, Z; Sun, Y; Yang, CS | 1 |
| Andreasen, PA; Gao, S; Krogdahl, A; Skeldal, S; Sørensen, JA | 1 |
| Ding, F; Guo, M; Li, J; Li, W; Liu, Z; Wang, Y; Wu, M; Yu, Z; Zhan, Q; Zhang, L | 1 |
| Bai, T; Tanaka, T; Umesaki, N; Yukawa, K | 1 |
| Hu, L; Huang, G; Sun, D; Tang, A; Van, do N; Zhang, Z | 1 |
| Chen, GA; Figg, WD; Fischette, MR; Hancox, A; Hong, JA; Kunst, TF; Li, X; Murgo, AJ; Nguyen, DM; Pishchik, V; Schrump, DS; Steinberg, SM; Zhao, M | 1 |
| Fields, CR; Pan, YX; Robertson, KD; Su, N; Zhong, S | 1 |
| Abraham, JM; Cheng, Y; Greenwald, BD; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Mori, Y; Paun, BC; Sato, F; Wang, S; Yang, J | 1 |
| Euhus, DM; Fong, KM; Gao, B; Gazdar, AF; Gerald, W; Girard, L; Jiang, A; Kim, YH; Lam, CL; Lewis, CM; Minna, JD; Nanda, R; Olopade, OI; Perou, CM; Pollack, JR; Sato, M; Shames, DS; Shay, JW; Shivapurkar, N; Shyr, Y; Wong, M | 1 |
| Fujisawa, T; Gazdar, AF; Iizasa, T; Minna, JD; Shames, DS; Shigematsu, H; Shivapurkar, N; Sunaga, N; Suzuki, M; Takahashi, T | 1 |
| Dietz, A; Tannapfel, A; Tischoff, I; Weber, A | 1 |
| Chen, Y; Deutschmann, N; Knösel, T; Kotb, WF; Lund, P; Pacyna-Gengelbach, M; Petersen, I; Schlüns, K; Sers, C; Usui, T; Yasumoto, H; Ye, F | 1 |
| Wang, H; Xia, B; Yi, ZC; Zhang, GY | 1 |
| Aiko, S; Imoto, I; Inazawa, J; Inoue, J; Iwai, T; Kawano, T; Kozaki, K; Shimada, Y; Tanaka, K; Tsuda, H; Yoshizumi, Y | 1 |
| Bennett, KL; Eng, C; Hackanson, B; Lang, JC; Morrison, CD; Plass, C; Schuller, DE; Smith, LT; Weber, F | 1 |
| Amagasa, T; Imoto, I; Inazawa, J; Kamata, N; Kozaki, KI; Nakagawa, T; Pimkhaokham, A; Suzuki, E | 1 |
| Akiyoshi, J; Aoki, D; Banno, K; Fujii, T; Hirasawa, A; Iwata, T; Kawaguchi, M; Kobayashi, Y; Kuwabara, Y; Susumu, N; Tsukazaki, K; Yanokura, M | 1 |
| Bhawal, UK; Kuniyasu, H; Mori, Y; Muto, N; Sasahira, T; Sato, F; Sugiyama, M; Tsukinoki, K | 1 |
| Li, K; Li, Z; Teng, L; Wei, L; Wu, K; Yu, P; Zhang, C; Zhu, J | 1 |
| Hu, J; Long, C; Lu, Q; Yang, Y; Yin, B; Yu, F; Yuan, Y; Zhou, X | 1 |
| Bianco, AR; Caraglia, M; Correale, P; Genua, G; Leardi, A; Pepe, S; Pinto, A; Tagliaferri, P; Zagonel, V | 1 |
| Chanock, RM; Crowe, JE; Davis, AR; Hsu, KH; Hung, PP; Lubeck, MD; Murphy, BR | 1 |
| Blessing, JA; Manetta, A; Mann, WJ; Smith, DM | 1 |
| Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D | 1 |
| Côté, S; Momparler, RL | 1 |
| Ayoub, J; Belanger, K; Bouffard, DY; Dionne, J; Momparler, LF; Momparler, RL | 1 |
| Harada, H; Hatooka, S; Imamura, M; Ishizaki, K; Shimada, Y; Shinoda, M; Tanaka, H | 1 |
| Concha, A; Garrido, F; Hortas, ML; Morell, M; Redondo, M; Ruiz-Cabello, F; Serrano, A | 1 |
| Hinds, PW; Münger, K; Timmermann, S | 1 |
| Emi, M; Kirita, T; Konishi, N; Nagai, H; Nishimine, M; Sugimura, M; Yamamoto, K | 1 |
| Alcalde, RE; Matsumura, T; Mese, H; Nakayama, S; Sasaki, A; Tsuji, T | 1 |
| Liao, J; Nie, Y; So, C; Song, Y; Wang, LD; Yang, CS; Yang, G; Zhao, X | 1 |
| Araki, D; Miyakawa, A; Shiiba, M; Tanzawa, H; Uzawa, K; Watanabe, T; Yokoe, H | 1 |
| Ono, K; Suzuki, H; Tanaka, C; Tanzawa, H; Uzawa, K; Yakushiji, T; Yamamoto, N; Yokoe, H | 1 |
| Hashimoto, K; Kato, H; Nakamura, K; Sasaki, K; Tamura, H; Tsuyama, S | 1 |
| Abele, R; Bruntsch, U; Clavel, M; Dodion, P; Gundersen, S; Pinedo, HM; Renard, J; Smyth, J; van Glabbeke, M | 1 |
| Diamant, M; Due, C; Olsson, L | 1 |
3 review(s) available for azacitidine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Promoter methylation of MGMT in oral carcinoma: A population-based study and meta-analysis.
Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; India; Mouth Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Sensitivity and Specificity | 2017 |
[Progress in research on DNA methylation and laryngeal carcinoma].
Topics: Acid Anhydride Hydrolases; Animals; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Genes, p16; Humans; Laryngeal Neoplasms; Neoplasm Proteins; Tumor Suppressor Proteins | 2011 |
[Role of epigenetics in the carcinogenesis of head and neck carcinomas - possible new targeted therapy?].
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Division; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Suppressor; Otorhinolaryngologic Neoplasms; Promoter Regions, Genetic; Targeted Gene Repair; Tumor Cells, Cultured | 2007 |
6 trial(s) available for azacitidine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Randomised phase 2 study of pembrolizumab plus CC-486 versus pembrolizumab plus placebo in patients with previously treated advanced non-small cell lung cancer.
Topics: Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Progression-Free Survival; Survival Rate; Treatment Outcome | 2019 |
Phase II trial of cisplatin plus decitabine, a new DNA hypomethylating agent, in patients with advanced squamous cell carcinoma of the cervix.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Squamous Cell; Cisplatin; Decitabine; Enzyme Inhibitors; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Uterine Cervical Neoplasms | 2002 |
Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura.
Topics: Adult; Aged; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Decitabine; DNA Modification Methylases; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Membrane Proteins; Mesothelioma; Middle Aged; Neoplasm Proteins; Pleural Neoplasms; Transcriptional Activation | 2006 |
A phase II study of fazarabine (NSC 281272) in patients with advanced squamous cell carcinoma of the cervix. A Gynecologic Oncology Group study.
Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Female; Humans; Middle Aged; Uterine Cervical Neoplasms | 1995 |
Pilot phase I-II study on 5-aza-2'-deoxycytidine (Decitabine) in patients with metastatic lung cancer.
Topics: Adult; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Decitabine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Tumor Cells, Cultured | 1997 |
The EORTC Early Clinical Trials Cooperative Group experience with 5-aza-2'-deoxycytidine (NSC 127716) in patients with colo-rectal, head and neck, renal carcinomas and malignant melanomas.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Decitabine; Female; Hematologic Diseases; Humans; Male; Melanoma; Middle Aged; Neoplasms | 1987 |
127 other study(ies) available for azacitidine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
5-Azacitidine and Trichostatin A induce DNA damage and apoptotic responses in tongue squamous cell carcinoma: An in vitro study.
Topics: Azacitidine; Carcinoma, Squamous Cell; Decitabine; DNA Damage; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Matrix Metalloproteinase 2; Tongue; Tongue Neoplasms | 2022 |
Cytotoxic Effects of 5-Azacytidine on Primary Tumour Cells and Cancer Stem Cells from Oral Squamous Cell Carcinoma: An In Vitro FTIRM Analysis.
Topics: Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Mouth Neoplasms; Spectroscopy, Fourier Transform Infrared; Squamous Cell Carcinoma of Head and Neck; Tumor Cells, Cultured | 2021 |
Repression of DOK7 mediated by DNMT3A promotes the proliferation and invasion of KYSE410 and TE-12 ESCC cells.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Muscle Proteins; Neoplasm Invasiveness; Promoter Regions, Genetic | 2017 |
Epigenetically silenced PTPRO functions as a prognostic marker and tumor suppressor in human lung squamous cell carcinoma.
Topics: Adult; Aged; Animals; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; CpG Islands; Decitabine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Heterografts; Humans; Lung Neoplasms; Male; Mice; Middle Aged; Prognosis; Receptor-Like Protein Tyrosine Phosphatases, Class 3 | 2017 |
Krüppel-Like Factor 4 Enhances Sensitivity of Cisplatin to Esophageal Squamous Cell Carcinoma (ESCC) Cells.
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Silencing; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Promoter Regions, Genetic | 2017 |
PAQR3 overexpression suppresses the aggressive phenotype of esophageal squamous cell carcinoma cells via inhibition of ERK signaling.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Membrane Proteins; Mice; Mice, Nude; Middle Aged; Neoplasm Staging; Phenotype; RNA, Messenger; Signal Transduction | 2017 |
Demethylation Therapy as a Targeted Treatment for Human Papillomavirus-Associated Head and Neck Cancer.
Topics: Animals; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Mice, Nude; Papillomaviridae; Papillomavirus Infections; Xenograft Model Antitumor Assays | 2017 |
Topics: Adult; Aged; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Early Detection of Cancer; Epigenesis, Genetic; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Promoter Regions, Genetic; Trefoil Factor-1 | 2017 |
Aberrant methylation of EYA4 promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma.
Topics: Animals; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; DNA Methylation; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Nude; Middle Aged; RNA Interference; Trans-Activators; Transplantation, Heterologous | 2018 |
Endoglin promoter hypermethylation identifies a field defect in human primary esophageal cancer.
Topics: Adenocarcinoma; Aged; Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Decitabine; DNA Methylation; Endoglin; Esophageal Neoplasms; Esophagus; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Staging; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; ROC Curve; Tumor Cells, Cultured | 2013 |
MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Case-Control Studies; Decitabine; DNA Methylation; Esophageal Neoplasms; Esophagus; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Myelin and Lymphocyte-Associated Proteolipid Proteins; Neoplasm Grading; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; ROC Curve; Tumor Cells, Cultured | 2013 |
Alteration of runt-related transcription factor 3 gene expression and biologic behavior of esophageal carcinoma TE-1 cells after 5-azacytidine intervention.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Squamous Cell; Cell Adhesion; Cell Movement; Cell Proliferation; Core Binding Factor Alpha 3 Subunit; DNA Methylation; DNA, Neoplasm; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2013 |
Epigenetic inactivation of SPINT2 is associated with tumor suppressive function in esophageal squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Squamous Cell; DNA Methylation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Male; Membrane Glycoproteins; Middle Aged; Promoter Regions, Genetic; Tumor Cells, Cultured | 2014 |
Promoter methylation-mediated downregulation of PRDM5 contributes to the development of lung squamous cell carcinoma.
Topics: Adult; Aged; Animals; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Female; Humans; Lung Neoplasms; Male; Mice; Middle Aged; Promoter Regions, Genetic; Transcription Factors | 2014 |
Promoter methylation‑associated silencing of p27kip1 gene with metastasis in esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Decitabine; DNA Methylation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation; Gene Silencing; Humans; Lymphatic Metastasis; Male; Promoter Regions, Genetic; RNA, Messenger | 2014 |
High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cell Movement; Cisplatin; Decitabine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Keratinocytes; Male; Middle Aged; Prognosis; rab GTP-Binding Proteins; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome | 2013 |
Correlation of deregulated like-acetylglucosaminyl transferase and aberrant α-dystroglycan expression with human tongue cancer metastasis.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Dystroglycans; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Glycosylation; Humans; Immunohistochemistry; Laminin; Lymphatic Metastasis; Male; Middle Aged; N-Acetylglucosaminyltransferases; Neoplasm Invasiveness; Neoplasm Staging; Plasmids; Promoter Regions, Genetic; Tongue Neoplasms; Transfection | 2014 |
Development of TRAIL resistance by radiation-induced hypermethylation of DR4 CpG island in recurrent laryngeal squamous cell carcinoma.
Topics: Aged; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; CpG Islands; Decitabine; DNA Methylation; Dose-Response Relationship, Radiation; Epigenesis, Genetic; Female; Flow Cytometry; Gene Silencing; Humans; Immunohistochemistry; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Oligonucleotide Array Sequence Analysis; Receptors, TNF-Related Apoptosis-Inducing Ligand; Reverse Transcriptase Polymerase Chain Reaction; TNF-Related Apoptosis-Inducing Ligand | 2014 |
Decreased expression of RASSF1A and up-regulation of RASSF1C is associated with esophageal squamous cell carcinoma.
Topics: Adult; Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Esophageal Neoplasms; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Promoter Regions, Genetic; RNA, Messenger; Tumor Suppressor Proteins | 2014 |
Aberrant methylation and decreased expression of the TGF-β/Smad target gene FBXO32 in esophageal squamous cell carcinoma.
Topics: Adult; Aged; Azacitidine; Calmodulin-Binding Proteins; Carcinoma, Squamous Cell; Cell Growth Processes; Decitabine; DNA Methylation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Silencing; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Middle Aged; Muscle Proteins; Promoter Regions, Genetic; RNA, Messenger; SKP Cullin F-Box Protein Ligases; Smad Proteins; Transforming Growth Factor beta; Up-Regulation | 2014 |
Epigenetic repression of HOXB cluster in oral cancer cell lines.
Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenetic Repression; Genes, Homeobox; Homeodomain Proteins; Humans; Mouth Neoplasms; Polymerase Chain Reaction; Transcription Factors | 2014 |
Temporal evolution in caveolin 1 methylation levels during human esophageal carcinogenesis.
Topics: Adenocarcinoma; Area Under Curve; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Caveolin 1; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; RNA, Messenger; ROC Curve; Time Factors | 2014 |
Demethylating drugs as novel analgesics for cancer pain.
Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cytidine; Decitabine; Disease Models, Animal; DNA Methylation; Heterografts; Humans; Immunohistochemistry; In Situ Hybridization; Mice; Mouth Neoplasms; Neurons; Pain; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; Transduction, Genetic; Trigeminal Ganglion | 2014 |
Low-dose decitabine induces MAGE-A expression and inhibits invasion via suppression of NF-κB2 and MMP2 in Eca109 cells.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B p52 Subunit | 2014 |
MicroRNA-125a reduces proliferation and invasion of oral squamous cell carcinoma cells by targeting estrogen-related receptor α: implications for cancer therapeutics.
Topics: Amino Acid Sequence; Animals; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Molecular Sequence Data; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Transplantation; Plasmids; Protein Binding; Sequence Homology, Amino Acid | 2014 |
Decitabine rescues cisplatin resistance in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Transcriptome; Xenograft Model Antitumor Assays; Young Adult | 2014 |
Downregulation of the microRNA-1/133a cluster enhances cancer cell migration and invasion in lung-squamous cell carcinoma via regulation of Coronin1C.
Topics: Aged; Aged, 80 and over; Azacitidine; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Microfilament Proteins; MicroRNAs; Middle Aged; Multigene Family; Neoplasm Invasiveness; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2015 |
RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Alternative Splicing; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cytidine Triphosphate; DNA Methylation; Esophageal Neoplasms; Esophagus; Female; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Humans; Hydroxamic Acids; Male; Middle Aged; Monomeric GTP-Binding Proteins; Neoplasm Invasiveness; Prognosis; Promoter Regions, Genetic; Protein Isoforms; Protein Synthesis Inhibitors; RNA, Messenger, Stored | 2015 |
Radioresistance in a human laryngeal squamous cell carcinoma cell line is associated with DNA methylation changes and topoisomerase II α.
Topics: Antigens, Neoplasm; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epigenesis, Genetic; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Promoter Regions, Genetic; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Transcription, Genetic | 2015 |
Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine.
Topics: Acetylation; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Benzamides; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Survival; Decitabine; Depsipeptides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Pyridines; Transcriptome; Vorinostat | 2015 |
Sevoflurane attenuate hypoxia-induced VEGF level in tongue squamous cell carcinoma cell by upregulating the DNA methylation states of the promoter region.
Topics: Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Methyl Ethers; Molecular Sequence Data; Promoter Regions, Genetic; Protein Transport; Sevoflurane; Tongue Neoplasms; Up-Regulation; Vascular Endothelial Growth Factor A | 2015 |
Effect of DR4 promoter methylation on the TRAIL-induced apoptosis in lung squamous carcinoma cell.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Promoter Regions, Genetic; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand | 2015 |
Chlorin e6-mediated photodynamic effect diminishes therapeutic potential of 5-aza-2'-deoxycytidine-based whole-tumour-cell vaccine in mice bearing squamous cell carcinoma SCCVII.
Topics: Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Cancer Vaccines; Carcinoma, Squamous Cell; Cell Line, Tumor; Chlorophyllides; Decitabine; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Kaplan-Meier Estimate; Male; Mice; Mice, Inbred C3H; Photochemotherapy; Photosensitizing Agents; Porphyrins; Transplantation, Homologous | 2015 |
Methylation-mediated repression of potential tumor suppressor miR-203a and miR-203b contributes to esophageal squamous cell carcinoma development.
Topics: Adult; Aged; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; MicroRNAs; Middle Aged; Prognosis; Promoter Regions, Genetic | 2016 |
Epigenetic Repression of miR-218 Promotes Esophageal Carcinogenesis by Targeting ROBO1.
Topics: 3' Untranslated Regions; Azacitidine; Base Sequence; Binding Sites; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Epigenetic Repression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Order; Genetic Loci; Humans; MicroRNAs; Nerve Tissue Proteins; Receptors, Immunologic; RNA Interference; RNA, Messenger; Roundabout Proteins | 2015 |
γ-Synuclein Expression Is a Malignant Index in Oral Squamous Cell Carcinoma.
Topics: Azacitidine; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Disease Progression; DNA Methylation; gamma-Synuclein; Gene Expression; Humans; Mouth Neoplasms; Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2016 |
Aberrant GRK6 promoter methylation is associated with poor prognosis in hypopharyngeal squamous cell carcinoma.
Topics: Azacitidine; Carcinoma, Squamous Cell; Decitabine; DNA Methylation; Down-Regulation; G-Protein-Coupled Receptor Kinases; Gene Expression Regulation, Neoplastic; Humans; Hypopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Promoter Regions, Genetic; RNA Interference; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering | 2016 |
Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC.
Topics: 5-Methylcytosine; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Computational Biology; Down-Regulation; Epigenesis, Genetic; Humans; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Mixed Function Oxygenases; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Tumor Escape | 2016 |
Association of RUNX3 Methylation with Clinical Outcome and Cell Migration/Invasion in Laryngeal Squamous Cell Carcinoma.
Topics: Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Core Binding Factor Alpha 3 Subunit; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck; Time Factors | 2016 |
PRSS8 methylation and its significance in esophageal squamous cell carcinoma.
Topics: Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; Disease-Free Survival; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Male; Middle Aged; Promoter Regions, Genetic; RNA Interference; Sequence Homology, Nucleic Acid; Serine Endopeptidases | 2016 |
Downregulation of thrombospondin-1 by DNA hypermethylation is associated with tumor progression in laryngeal squamous cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Decitabine; Disease Progression; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Thrombospondin 1; Transcriptional Activation | 2016 |
UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma.
Topics: Aged; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; CCAAT-Enhancer-Binding Proteins; Cell Transformation, Neoplastic; Disease-Free Survival; DNA Methylation; Epigenesis, Genetic; Epigenomics; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagus; Female; Humans; Long Interspersed Nucleotide Elements; Male; Middle Aged; Prognosis; Proportional Hazards Models; Sequence Analysis, DNA; Treatment Outcome; Ubiquitin; Ubiquitin-Protein Ligases | 2016 |
DSS1 promoter hypomethylation and overexpression predict poor prognosis in melanoma and squamous cell carcinoma patients.
Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Male; Melanoma; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Skin Neoplasms; Time Factors; Treatment Outcome; Up-Regulation; Uveal Neoplasms | 2017 |
Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nuclear Proteins; Prognosis; Promoter Regions, Genetic; Signal Transduction; Survival Rate; Tumor Cells, Cultured; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2017 |
Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma.
Topics: Azacitidine; Blotting, Western; Carcinoma, Squamous Cell; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Male; Mouth Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Signal Transduction; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2008 |
Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cation Transport Proteins; Colony-Forming Units Assay; DNA Methylation; Epigenesis, Genetic; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; GTP Phosphohydrolases; Head and Neck Neoplasms; Homeodomain Proteins; Humans; Microtubule-Associated Proteins; Monocarboxylic Acid Transporters; Mucous Membrane; Nerve Tissue Proteins; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Septins; Transcription Factors | 2008 |
Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cathepsin L; Cathepsins; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cysteine Endopeptidases; Decitabine; DNA Methylation; DNA Modification Methylases; Esophageal Neoplasms; Esophagus; Fatty Acid-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
A systematic assessment of radiation dose enhancement by 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma.
Topics: Acetylation; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Reverse Transcriptase Polymerase Chain Reaction; Tumor Stem Cell Assay | 2009 |
T-lymphocyte maturation-associated protein gene as a candidate metastasis suppressor for head and neck squamous cell carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Heterozygote; Humans; Male; Membrane Transport Proteins; Middle Aged; Mutation; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Neoplasm Metastasis; Proteolipids; RNA, Messenger | 2009 |
Real-time PCR analysis of genes encoding tumor antigens in esophageal tumors and a cancer vaccine.
Topics: Aged; Antigens, Neoplasm; Azacitidine; Cancer Vaccines; Carcinoma, Squamous Cell; Clone Cells; Decitabine; DNA Modification Methylases; Epithelial Cells; Esophageal Neoplasms; Female; Gene Expression Profiling; Humans; Male; Middle Aged; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
FOXE1 is a target for aberrant methylation in cutaneous squamous cell carcinoma.
Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Forkhead Transcription Factors; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Neoplasm Proteins; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Skin Neoplasms | 2010 |
A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Cyclooxygenase 2; Decitabine; DNA Modification Methylases; Female; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Mouth Mucosa; Mouth Neoplasms; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myb; Receptors, Retinoic Acid; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin | 2009 |
Epigenetic silencing of CRABP2 and MX1 in head and neck tumors.
Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Head and Neck Neoplasms; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Myxovirus Resistance Proteins; Oligonucleotide Array Sequence Analysis; Prognosis; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; Tissue Array Analysis | 2009 |
Identification of hypermethylated genes associated with cisplatin resistance in human cancers.
Topics: Algorithms; Azacitidine; Calcium-Binding Proteins; Carcinoma, Squamous Cell; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Gene Silencing; Humans; KB Cells; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transcription, Genetic; Up-Regulation | 2010 |
Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione Peroxidase; Humans; Male; Middle Aged; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2011 |
Demethylation treatment restores hic1 expression and impairs aggressiveness of head and neck squamous cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Kruppel-Like Transcription Factors; Male; Middle Aged; Neoplasm Invasiveness; Promoter Regions, Genetic | 2010 |
Claudin-7 down-regulation is an important feature in oral squamous cell carcinoma.
Topics: Adult; Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Claudins; Decitabine; Down-Regulation; Female; Humans; Immunohistochemistry; Male; Membrane Proteins; Middle Aged; Mouth Neoplasms; RNA, Messenger | 2010 |
Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Decitabine; Dinoprostone; DNA Methylation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Promoter Regions, Genetic; RNA, Messenger; Sequence Analysis, DNA | 2011 |
Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Azacitidine; Cadherins; Carcinoma, Squamous Cell; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Shape; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Esophageal Neoplasms; Female; Humans; Male; Methylation; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Promoter Regions, Genetic; Transcription, Genetic | 2011 |
Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.
Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Decitabine; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Humans; Squamous Cell Carcinoma of Head and Neck; Tretinoin; Valproic Acid | 2012 |
Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Membrane Proteins | 2011 |
Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatin Immunoprecipitation; Cohort Studies; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Lung Neoplasms; Male; Matrix Attachment Region Binding Proteins; Middle Aged; Neoplasm Staging; Prognosis; Tissue Array Analysis | 2011 |
Aberrant methylation of N-methyl-D-aspartate receptor type 2B (NMDAR2B) in non-small cell carcinoma.
Topics: Adult; Aged; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Pneumonectomy; Prognosis; Proportional Hazards Models; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; RNA, Neoplasm; Sampling Studies | 2011 |
WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Blotting, Western; Carcinoma, Squamous Cell; Cell Line; Cervix Uteri; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoenzyme Techniques; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uterine Cervical Neoplasms | 2011 |
Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; C-Reactive Protein; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromosomes, Human, Pair 3; Decitabine; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Serum Amyloid P-Component | 2011 |
CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells.
Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Fatty Acid-Binding Proteins; Humans; PPAR delta; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; Skin Neoplasms; Tretinoin | 2012 |
Pharmacological genome demethylation increases radiosensitivity of head and neck squamous carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Promoter Regions, Genetic; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Transcriptional Activation | 2012 |
Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells.
Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; CpG Islands; Dealkylation; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Female; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Molecular Sequence Data; MutL Protein Homolog 1; Nuclear Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Sequence Analysis, DNA; Tumor Suppressor Proteins | 2012 |
Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Dealkylation; Death-Associated Protein Kinases; Decitabine; DNA Modification Methylases; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Uterine Cervical Neoplasms | 2012 |
Epigenetic screen of human DNA repair genes identifies aberrant promoter methylation of NEIL1 in head and neck squamous cell carcinoma.
Topics: Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Glycosylases; DNA Methylation; DNA Repair; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Keratinocytes; Male; Middle Aged; Promoter Regions, Genetic; Reference Values; Squamous Cell Carcinoma of Head and Neck | 2012 |
Differential fucosyltransferase IV expression in squamous carcinoma cells is regulated by promoter methylation.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Cytidine Triphosphate; DNA Methylation; Fucosyltransferases; Gene Expression Regulation, Neoplastic; Humans; Lewis X Antigen; Promoter Regions, Genetic | 2012 |
[Mechanism of loss of human esophageal cancer-related gene 4 (ECRG4) gene expression in esophageal squamous cell carcinoma cell line EC9706].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Esophageal Neoplasms; Exons; Gene Expression Regulation, Neoplastic; Humans; Mutation; Neoplasm Proteins; Oxides; Promoter Regions, Genetic; RNA, Messenger; Tumor Suppressor Proteins | 2011 |
Study on RIZ1 gene promoter methylation status in human esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Esophageal Neoplasms; Female; Gene Silencing; Histone-Lysine N-Methyltransferase; Humans; Male; Middle Aged; Molecular Sequence Data; Nuclear Proteins; Promoter Regions, Genetic; Sequence Analysis, DNA; Transcription Factors | 2012 |
Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone-Lysine N-Methyltransferase; Humans; Molecular Sequence Data; Nuclear Proteins; RNA, Messenger; Transcription Factors | 2012 |
Promoter methylation regulates cigarette smoke-stimulated cyclooxygenase-2 expression in esophageal squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclooxygenase 2; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Smoking | 2012 |
XAF1 is frequently methylated in human esophageal cancer.
Topics: Adaptor Proteins, Signal Transducing; Aged; Apoptosis Regulatory Proteins; Azacitidine; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Chi-Square Distribution; China; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators.
Topics: Antineoplastic Agents; Azacitidine; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Silencing; Genes, Tumor Suppressor; Grape Seed Extract; Histone Acetyltransferases; Humans; Immunoblotting; Proanthocyanidins; Real-Time Polymerase Chain Reaction; Skin Neoplasms | 2012 |
Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Exodeoxyribonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; RecQ Helicases; RNA, Small Interfering; Topoisomerase I Inhibitors; Uterine Cervical Neoplasms; Werner Syndrome Helicase | 2012 |
Clinical regression of squamous cell carcinoma and keratoacanthomas in a patient treated with a hypomethylating agent.
Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Humans; Immunosuppressive Agents; Keratoacanthoma; Kidney Transplantation; Male; Myelodysplastic Syndromes; Skin Neoplasms; Treatment Outcome | 2014 |
MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Reproducibility of Results; Transcriptional Activation | 2012 |
Abnormal hypermethylation and clinicopathological significance of Axin gene in lung cancer.
Topics: Adenocarcinoma; Axin Protein; Azacitidine; Base Sequence; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Molecular Sequence Data; Neoplasm Staging; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
miR-370 modulates insulin receptor substrate-1 expression and inhibits the tumor phenotypes of oral carcinoma.
Topics: Azacitidine; Carcinogenesis; Carcinoma, Squamous Cell; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cells, Cultured; Decitabine; DNA Modification Methylases; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Insulin Receptor Substrate Proteins; Keratinocytes; MicroRNAs; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Oncogene Protein v-akt; RNA, Small Interfering; TOR Serine-Threonine Kinases | 2013 |
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Azacitidine; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 8; CpG Islands; Decitabine; DNA Modification Methylases; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Loss of Heterozygosity; Lung Neoplasms; Nerve Tissue Proteins; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas.
Topics: Azacitidine; Blotting, Northern; Blotting, Southern; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 11; Cyclin D1; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Amplification; Gene Silencing; Humans; Neoplasm Proteins; Oncogene Proteins; Proto-Oncogene Proteins; Tumor Cells, Cultured | 2002 |
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
Topics: Azacitidine; Base Sequence; Carcinoma, Squamous Cell; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2002 |
Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.
Topics: Adenocarcinoma; Adult; Aged; Azacitidine; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 3; DNA Methylation; DNA Primers; DNA, Neoplasm; DNA, Viral; Enzyme Inhibitors; Female; Gene Silencing; Genes, Tumor Suppressor; Humans; Loss of Heterozygosity; Middle Aged; Mutation; Neoplasm Proteins; Neoplasm Staging; Papillomaviridae; Papillomavirus Infections; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tumor Virus Infections; Uterine Cervical Neoplasms | 2003 |
Down-regulation of FEZ1/LZTS1 gene with frequent loss of heterozygosity in oral squamous cell carcinomas.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Azacitidine; Carcinoma, Squamous Cell; Decitabine; Disease Progression; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; DNA, Neoplasm; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Leucine Zippers; Loss of Heterozygosity; Male; Microsatellite Repeats; Middle Aged; Mouth Neoplasms; Nerve Tissue Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.
Topics: Azacitidine; Breast Neoplasms; Carcinoma, Squamous Cell; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Gene Expression; Humans; Lung Neoplasms; Microsatellite Repeats; PAX5 Transcription Factor; Promoter Regions, Genetic; Transcription Factors; Tumor Cells, Cultured | 2003 |
Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Decitabine; DNA Methylation; Gene Silencing; Genes, p16; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids | 2003 |
Promoter methylation regulates cadherin switching in squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cadherins; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; DNA Methylation; Down-Regulation; Fluorescent Antibody Technique, Direct; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Mouth Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Esophageal Neoplasms; Gene Deletion; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Nucleic Acid Hybridization; Receptors, LDL; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Downregulation of connexin 26 in human lung cancer is related to promoter methylation.
Topics: Actins; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Northern; Blotting, Southern; Carcinoma, Squamous Cell; Cell Line, Tumor; Connexin 26; Connexins; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Immunohistochemistry; Lung Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA | 2005 |
Status of reduced expression and hypermethylation of the APC tumor suppressor gene in human oral squamous cell carcinoma.
Topics: Adenomatous Polyposis Coli Protein; Azacitidine; Carcinoma, Squamous Cell; DNA Methylation; Down-Regulation; Female; Humans; Immunohistochemistry; Male; Mouth Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells.
Topics: Acetylation; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin | 2005 |
Methylation-associated silencing of death-associated protein kinase gene in laryngeal squamous cell cancer.
Topics: Adult; Aged; Animals; Azacitidine; Carcinoma, Squamous Cell; Case-Control Studies; Cell Death; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Laryngeal Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Kinases; Reference Values; RNA, Messenger; Sampling Studies; Sensitivity and Specificity; Transplantation, Heterologous | 2005 |
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Esophageal Neoplasms; Genistein; Glycine max; Humans; Hydroxamic Acids; Isoflavones; Isothiocyanates; O(6)-Methylguanine-DNA Methyltransferase; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfites; Sulfoxides; Tea; Thiocyanates | 2005 |
CpG methylation of the PAI-1 gene 5'-flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines.
Topics: 5' Flanking Region; Azacitidine; Carcinoma, Squamous Cell; CpG Islands; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mouth Neoplasms; Plasminogen Activator Inhibitor 1; RNA, Messenger; Sequence Analysis, DNA; Time Factors; U937 Cells | 2005 |
5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Esophageal Neoplasms; Esophagus; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Receptors, Retinoic Acid; RNA, Messenger | 2005 |
A novel mechanism for acquired cisplatin-resistance: suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells.
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Death-Associated Protein Kinases; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA, Messenger; Uterine Cervical Neoplasms | 2006 |
Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma.
Topics: Adenocarcinoma; Azacitidine; Carcinoma, Squamous Cell; Case-Control Studies; Cell Proliferation; Colony-Forming Units Assay; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Nasopharyngeal Neoplasms; Nasopharynx; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2007 |
Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.
Topics: Acetylation; Adenocarcinoma; Azacitidine; Biomarkers, Tumor; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chromatin Immunoprecipitation; Colony-Forming Units Assay; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2007 |
Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression.
Topics: Adenocarcinoma; Aged; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; Esophageal Diseases; Esophageal Neoplasms; Female; Genetic Markers; Glycoproteins; Humans; Male; Middle Aged; Polymerase Chain Reaction; Precancerous Conditions | 2006 |
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Cathepsin K; Cathepsins; Colonic Neoplasms; CpG Islands; Cyclin A; Cyclin A1; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Profiling; Humans; Lung Neoplasms; Male; Middle Aged; MSX1 Transcription Factor; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Transcription Factors; Tumor Cells, Cultured | 2006 |
Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; CpG Islands; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Male; Middle Aged; Promoter Regions, Genetic; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 2007 |
Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer.
Topics: Adenocarcinoma; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Epithelial Cells; Humans; Immunohistochemistry; Insulin-Like Growth Factor Binding Proteins; Lung; Lung Neoplasms; Microarray Analysis; Neoplasm Staging; Transfection; Tumor Suppressor Proteins | 2007 |
Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Connexin 43; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Fluoresceins; Gap Junctions; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Nasopharyngeal Neoplasms; Promoter Regions, Genetic | 2007 |
Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma.
Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Differentiation; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lymphatic Metastasis; Male; Middle Aged; Promoter Regions, Genetic; Receptors, Retinoic Acid | 2007 |
Tumor suppressor activity of CCAAT/enhancer binding protein alpha is epigenetically down-regulated in head and neck squamous cell carcinoma.
Topics: Azacitidine; Carcinoma, Squamous Cell; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Loss of Heterozygosity; Neoplasm Metastasis; Transfection | 2007 |
PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Chromosomes, Human, Pair 10; CpG Islands; Decitabine; DNA Methylation; Gene Silencing; Genes, Tumor Suppressor; Humans; Mouth Neoplasms; Nucleic Acid Hybridization; Promoter Regions, Genetic; RNA, Messenger | 2007 |
Epigenetic inactivation of the CHFR gene in cervical cancer contributes to sensitivity to taxanes.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Bridged-Ring Compounds; Carcinoma, Squamous Cell; Cell Cycle Proteins; DNA Methylation; DNA, Neoplasm; Drug Tolerance; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Neoplasm Proteins; Poly-ADP-Ribose Binding Proteins; Promoter Regions, Genetic; RNA, Small Interfering; Taxoids; Tumor Cells, Cultured; Ubiquitin-Protein Ligases; Uterine Cervical Neoplasms | 2007 |
Methylation and intratumoural heterogeneity of 14-3-3 sigma in oral cancer.
Topics: 14-3-3 Proteins; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cyclin D; Cyclins; DNA Methylation; Enzyme Inhibitors; Exonucleases; Exoribonucleases; Female; Gene Expression Regulation, Neoplastic; Gingiva; Humans; Male; Middle Aged; Mouth Neoplasms; Mutation; Neoplasm Proteins; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2007 |
p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma.
Topics: Azacitidine; Carcinoma, Squamous Cell; Decitabine; DNA Methylation; DNA, Neoplasm; E1A-Associated p300 Protein; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lymphatic Metastasis; Male; Neoplasm Invasiveness; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm | 2007 |
Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma.
Topics: Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; DNA Methylation; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta | 2007 |
5-Aza-2'-deoxycytidine induces growth inhibition and upregulation of epidermal growth factor receptor on human epithelial cancer cells.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Division; Decitabine; Endocytosis; ErbB Receptors; Humans; KB Cells; Tumor Cells, Cultured; Up-Regulation | 1994 |
Isolation and characterization of a highly attenuated respiratory syncytial virus (RSV) vaccine candidate by mutagenesis of the incompletely attenuated RSV A2 ts-1 NG-1 mutant virus.
Topics: Animals; Azacitidine; Carcinoma, Squamous Cell; Chlorocebus aethiops; Female; Fluorouracil; Male; Mice; Mice, Inbred BALB C; Mutagenesis; Pan troglodytes; Phenotype; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Temperature; Tumor Cells, Cultured; Vaccines, Attenuated; Vero Cells; Viral Vaccines; Virus Replication | 1995 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Evaluation of the antineoplastic activity of adozelesin alone and in combination with 5-aza-2'-deoxycytidine and cytosine arabinoside on DLD-1 human colon carcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzofurans; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Cyclohexanecarboxylic Acids; Cyclohexenes; Cytarabine; Decitabine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Duocarmycins; Humans; Indoles; Lung Neoplasms; Time Factors; Tumor Cells, Cultured | 1993 |
Methylation of the 5' CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas.
Topics: Acid Anhydride Hydrolases; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Squamous Cell; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Esophageal Neoplasms; Exons; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Neoplasm Proteins; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proteins; Transcriptional Activation; Tumor Cells, Cultured | 1998 |
Differential expression of MHC class II genes in lung tumour cell lines.
Topics: Actins; Adenocarcinoma; Antibodies, Monoclonal; Azacitidine; Blotting, Northern; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Decitabine; Densitometry; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression; Genes, MHC Class II; Genes, myc; HLA-DP Antigens; HLA-DQ Antigens; HLA-DR Antigens; Humans; Interferon-gamma; Lung Neoplasms; Proto-Oncogene Mas; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Re-expression of endogenous p16ink4a in oral squamous cell carcinoma lines by 5-aza-2'-deoxycytidine treatment induces a senescence-like state.
Topics: Azacitidine; beta-Galactosidase; Carcinoma, Squamous Cell; Cellular Senescence; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Humans; Mouth Neoplasms; Mutation; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Recombinant Proteins; Retinoblastoma Protein; Retroviridae; Tumor Cells, Cultured | 1998 |
Epigenetic alterations in methylation in oral squamous cell carcinoma cell lines detected by two-dimensional gel electrophoresis.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Decitabine; DNA Methylation; DNA, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Humans; Mouth Neoplasms; Restriction Mapping; Tumor Cells, Cultured | 2000 |
The E-cadherin gene is silenced by CpG methylation in human oral squamous cell carcinomas.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cadherins; Carcinoma, Squamous Cell; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mouth Neoplasms; Promoter Regions, Genetic; Tumor Cells, Cultured | 2001 |
DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas.
Topics: Azacitidine; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 6; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; DNA, Neoplasm; Down-Regulation; Esophageal Neoplasms; Gene Deletion; Genes, MHC Class I; Histocompatibility Antigens Class I; Humans; Immunoenzyme Techniques; Loss of Heterozygosity; Microsatellite Repeats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Frequent allelic losses on the short arm of chromosome 1 and decreased expression of the p73 gene at 1p36.3 in squamous cell carcinoma of the oral cavity.
Topics: Azacitidine; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 1; Decitabine; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genotype; Humans; Loss of Heterozygosity; Male; Microsatellite Repeats; Mouth Neoplasms; Nuclear Proteins; Phenotype; Physical Chromosome Mapping; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Deletion; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Proteins | 2002 |
High prevalence of decreased expression of KAI1 metastasis suppressor in human oral carcinogenesis.
Topics: Aged; Alleles; Antigens, CD; Azacitidine; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 11; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; DNA, Neoplasm; Enzyme Inhibitors; Epithelium; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Kangai-1 Protein; Male; Membrane Glycoproteins; Middle Aged; Mouth Neoplasms; Neoplasm Metastasis; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Different behaviors in the production and release of SCC antigen in squamous-cell carcinoma.
Topics: Animals; Antigens, Neoplasm; Azacitidine; Carcinoma, Squamous Cell; Cell Count; Cell Division; Female; Immunohistochemistry; Intracellular Fluid; Mice; Mice, Nude; Serpins; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1991 |
Treatment of human cell lines with 5-azacytidine may result in profound alterations in clonogenicity and growth rate.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Humans; Lung Neoplasms; Lymphoma; Multiple Myeloma | 1985 |