azacitidine has been researched along with Carcinoma, Anaplastic in 74 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (2.70) | 18.7374 |
1990's | 5 (6.76) | 18.2507 |
2000's | 33 (44.59) | 29.6817 |
2010's | 32 (43.24) | 24.3611 |
2020's | 2 (2.70) | 2.80 |
Authors | Studies |
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Athwal, RS; Kandpal, RP; Zhawar, VK | 1 |
Wang, Y; Zhu, P | 1 |
Liu, J; Liu, W; Luo, B; Wang, J; Zhao, Z | 1 |
Bendinelli, P; Desiderio, MA; Locatelli, A; Maroni, P; Matteucci, E | 1 |
Bultmann, I; Conradi, A; Kretschmer, C; Sterner-Kock, A | 1 |
Hinoda, Y; Morishige, A; Nakamura, M; Nishikawa, J; Oga, A; Okada, T; Saito, M; Sakai, K; Sakaida, I; Sasaki, K; Suehiro, Y; Zhang, Y | 1 |
Gong, P; Li, J; Li, X; Lyu, X; Peng, H; Yao, K | 1 |
Chen, M; Fan, H; Feng, K; Fu, X; Guo, B; Han, W; Liu, Y; Lu, X; Nie, J; Shi, F; Wang, X; Wang, Y; Zhang, W; Zhang, Y; Zhu, H | 1 |
Allaya, N; Ayadi, W; Daoud, J; Frikha, H; Frikha, M; Gargouri, A; Ghorbel, A; Khabir, A; Mokdad-Gargouri, R; Trigui, E | 1 |
Claret, FX; Wang, S; Yang, H; Zhang, R | 1 |
Liu, ZH; Luo, FY; Tang, CE; Xiao, S; Xiao, ZQ; Zhang, PF | 1 |
Almgren, M; Du, ZM; Ernberg, I; Hu, LF; Ignatyev, I; Kashuba, V; Moumad, K; Nawaz, I; Pavlova, TV; Zabarovsky, ER | 1 |
Borikun, TV; Burlaka, AP; Chekhun, VF; Demash, DV; Lozovska, YV; Lukianova, NY; Naleskina, LA; Pavlova, AO; Storchay, DM; Todor, IN; Yalovenko, TM; Zadvornyi, TV | 1 |
Ahuja, N; Baylin, SB; Costello, JF; Easwaran, H; Eberhart, CG; Glöckner, SC; Herman, JG; James, CD; Laterra, J; Lin, S; Ohm, JE; Riggins, G; Schuebel, KE; Tsai, HC; Vescovi, AL; Yi, JM | 1 |
Agate, L; Capodanno, A; Ciampi, R; Collecchi, P; Elisei, R; Miasaki, FY; Pinchera, A; Vivaldi, A | 1 |
Krynetskaia, NF; Krynetskiy, E; Mishra, AK; Phadke, MS | 1 |
Bazarov, AV; Hines, WC; Mukhopadhyay, R; Yaswen, P | 1 |
Egan, LJ; Foran, E; Garrity-Park, MM; Limburg, PJ; Mureau, C; Newell, J; Smyrk, TC | 1 |
Chan, JY; Ho, WK; Man, OY; To, VS; Tsang, CM; Tsang, RK; Tsao, SW; Wei, WI; Wong, TS | 1 |
Arvia, R; Deledda, C; Gelmini, S; Luciani, P; Malentacchi, F; Mannelli, M; Orlando, C; Peri, A; Simi, L | 1 |
Higashi, M; Houjou, I; Kitamoto, S; Yamada, N; Yokoyama, S; Yonezawa, S | 1 |
Chan, AW; Chan, MW; Chau, SL; Lee, TL; Leung, PP; Lo, KW; Lung, RW; Ng, DC; So, KK; To, KF; Tong, JH | 1 |
Du, C; Huang, G; Huang, T; Lin, L; Ma, N; Mo, Y; Murata, M; Wang, S; Xiao, X; Yu, N; Zhang, J; Zhang, Z; Zhou, X | 1 |
Gamo, T; Habano, W; Otsuka, K; Ozawa, S; Sugai, T; Terashima, J; Wakabayashi, G | 1 |
Feng, L; Wu, Y; Xie, Y; Zhang, H | 1 |
Dong, X; Korch, C; Meinkoth, JL | 1 |
Hayashi, Y; Imai, T; Kikumori, T; Kiuchi, T; Kurebayashi, J; Murata, Y; Sassa, M; Watanabe, R | 1 |
Becker, K; Hapfelmeier, A; Höfler, H; Keller, G; Langer, R; Mutze, K; Novotny, A; Ott, K; Schumacher, F | 1 |
Auersperg, N; Cheng, JC; Leung, PC | 1 |
Akerström, G; Björklund, P; Carling, T; Dralle, H; Lifton, RP; Starker, LF; Svedlund, J; Udelsman, R; Westin, G | 1 |
Guo, J; Guo, L; Han, X; Li, J; Qu, Q; Sun, HD; Tan, WH; Yi, TZ | 1 |
Cho, BN; Cho, C; Kim, BH; Kim, YI; Lee, HK; Lee, SJ; Shim, J | 1 |
Chen, R; Hu, Q; Ji, L; Liao, QP; Wang, YL; Xie, Y; Yu, L; Zhang, Y | 1 |
Chan, SH; Chen, H; Cheung, FM; Chiu, PM; Chua, D; Hyytiainen, M; Kan, R; Keski-Oja, J; Ko, JM; Kwong, DL; Lee, AW; Lung, ML; Nicholls, JM; Stanbridge, EJ; Tao, Q; Tsao, SW; Wong, VC; Zabarovsky, ER | 1 |
He, G; Li, H; Li, W; Ma, Y; Tan, G; Zhang, X | 1 |
Andry, G; De Martelar, V; Dom, G; Dumont, JE; Galdo, VC; Hébrant, A; Leteurtre, E; Libert, F; Maenhaut, C; Tarabichi, M; Tomás, G; van Staveren, WC | 1 |
Byun, DW; Chun, SW; Jung, CH; Kang, SG; Kim, BY; Kim, CH; Kim, SJ; Kim, YJ; Ko, HJ; Mok, JO; Park, HK; Suh, KI; Yoo, MH | 1 |
Chan, A; Chang, HW; Kwong, DL; Sham, JS; Wei, WI; Yuen, AP | 1 |
Chen, HK; Feng, QS; Li, A; Liu, XQ; Long, QX; Pan, ZG; Wang, XZ; Zeng, YX; Zhang, XS | 1 |
Benoit, NE; Dong, SM; Kuzmin, I; Lerman, MI; Sidransky, D; Sun, DI | 1 |
Chayama, K; Ito, R; Kitadai, Y; Nakayama, H; Oshimo, Y; Yasui, W; Yoshida, K | 1 |
Anderton, JA; Bailey, S; Clifford, SC; Ellison, DW; Gilbertson, RJ; Lindsey, JC; Lusher, ME; Pearson, AD | 1 |
Akiyama, Y; Fujisawa, K; Honda, T; Ishida, K; Itabashi, T; Maesawa, C; Masuda, T; Noda, Y; Saito, K; Sato, N; Takagane, A; Wada, K | 1 |
Lim, CY; Loh, KS; Qiu, GH; Srivastava, G; Tan, LK; Tao, Q; Tsai, ST; Tsao, SW | 1 |
Butcher, DT; Haines, TR; Rodenhiser, DI; Sadikovic, B | 1 |
Bilchik, AJ; Fujimoto, A; Hoon, DS; Shinozaki, M; Takeuchi, H; Umetani, N | 1 |
Biesová, Z; Jakubicková, L; Kettmann, R; Pastorek, J; Pastoreková, S | 1 |
Bae, SI; Jee, CD; Kim, WH; Lee, HS; Lee, YM; Rho, MS; Yang, HK | 1 |
End-Pfützenreuter, A; Fong, KM; Gazdar, AF; Girard, L; Heller, G; Lang, G; Minna, JD; Seidl, S; Zielinski, CC; Zöchbauer-Müller, S | 1 |
Chan, AT; Langford, C; Li, H; Murray, P; Putti, T; Seng, TJ; Srivastava, G; Tao, Q; Tsao, SW; Ying, J | 1 |
Chen, JK; Chou, J; He, B; Jablons, DM; Kim, J; Kuchenbecker, K; Lin, YC; Mikami, I; Raz, D; Thung, E; Xu, Z; Yang, CT; You, L | 1 |
Chen, H; Costa, M; Ke, Q; Kluz, T; Yan, Y | 1 |
Domann, FE; Howe, JR; Lal, G; Nicholson, RM; O'Dorisio, MS; Padmanabha, L; Smith, BJ | 1 |
Berger, W; Depisch, D; Filipits, M; Geradts, J; Heller, G; Kandioler, D; Markis-Ritzinger, EM; Newsham, I; Pirker, R; Stiglbauer, W; Ziegler, B; Zielinski, CC; Zöchbauer-Müller, S | 1 |
Chan, AT; Chan, SL; Cui, Y; Jin, H; Lee, KY; Li, H; Ng, KM; Rha, SY; Robertson, KD; Srivastava, G; Tao, Q; Tsao, GS; van Hasselt, A; Wang, Y; Zhong, S | 1 |
Li, H; Peng, D; Ren, CP; Wang, L; Yao, KT; Yi, HM; Zhang, HJ; Zhao, M | 1 |
Baek, JH; Chang, X; Dasgupta, S; Kim, MS; Moon, C; Nagpal, JK; Osada, M; Ratovitski, EA; Sidransky, D; Trink, B; Westra, WH; Woo, JH; Wu, G; Yamashita, K | 1 |
Fukuyoshi, Y; Inoue, H; Ishii, H; Kita, Y; Mimori, K; Mori, M; Motoyama, K; Ohta, M; Yamashita, K | 1 |
Ethier, SP; Hanifi-Moghaddam, P; Hollestelle, A; Klijn, JG; Merajver, SD; Schutte, M; van den Ouweland, A; Wasielewski, M | 1 |
Cortese, R; de Leij, LFMH; Jeltsch, A; Kiss, A; McLaughlin, PMJ; Monami, A; Raskó, T; Rots, MG; Ruiters, MHJ; Ślaska-Kiss, K; van der Gun, BTF; Wasserkort, R; Weinhold, E | 1 |
Chahinian, AP; Greenfield, DS; Holland, JF; Ohnuma, T | 1 |
Hirohashi, S; Kanai, Y; Ochiai, A; Shimoyama, Y; Sugimura, T; Yoshiura, K | 1 |
Chae, HS; Chen, A; Deng, G; Hong, J; Kim, YS | 1 |
Bang, YJ; Choi, HH; Inoue, H; Jong, HS; Kim, NK; Song, SH; Tanabe, T | 1 |
Ito, R; Kuniyasu, H; Kuraoka, K; Oue, N; Shigeishi, H; Yasui, W; Yokozaki, H | 1 |
Cheung, AL; Lam, KY; Liu, Y; Shen, ZY; Si, HX; Srivastava, G; Tsao, SW; Wong, YC | 1 |
Crichton, DN; Hupp, TR; Kernohan, N; McDowell, HE; Nicoll, G; Thompson, AM | 1 |
Biesta, P; Quinten, E; van den Elsen, PJ; van der Stoep, N | 1 |
Dallol, A; Forgacs, E; Kishida, T; Latif, F; Maher, ER; Martinez, A; Minna, JD; Rabbitts, P; Sekido, Y; Walker, R | 1 |
Bae, SI; Kim, SH; Kim, WH; Lee, HS | 1 |
Abbruzzese, JL; Ajani, JA; Daugherty, K; Hubbard, KP; Levin, B; Pazdur, R | 1 |
Esparza, L; Holmes, FA; Hortobagyi, GN; Theriault, RL; Walters, RS | 1 |
Cavalli, F; Renard, J; Sessa, C; Stoter, G; ten Bokkel Huinink, W | 1 |
Takenaga, K | 1 |
1 review(s) available for azacitidine and Carcinoma, Anaplastic
Article | Year |
---|---|
Modification of the metastatic potential of tumor cells by drugs.
Topics: Animals; Azacitidine; Butyrates; Butyric Acid; Carcinoma; Cell Division; Cell Line; Cells, Cultured; Dimethyl Sulfoxide; Lung Neoplasms; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Cells, Circulating; Phenotype | 1986 |
3 trial(s) available for azacitidine and Carcinoma, Anaplastic
Article | Year |
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Low-dose decitabine-based chemoimmunotherapy for patients with refractory advanced solid tumors: a phase I/II report.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Decitabine; DNA Methylation; DNA Modification Methylases; Double-Blind Method; Doxorubicin; Female; Humans; Immunotherapy; Killer Cells, Natural; Lymphoma; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms; Prednisone; Prospective Studies; Survival Analysis; Vincristine | 2014 |
Phase II trial of fazarabine in advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Carcinoma; Colorectal Neoplasms; Drug Administration Schedule; Drug Evaluation; Humans; Male; Middle Aged | 1992 |
Phase II trial of fazarabine (ARA-AC, arabinosyl-5-azacytosine) in metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Breast Neoplasms; Carcinoma; Drug Evaluation; Female; Humans; Middle Aged | 1992 |
70 other study(ies) available for azacitidine and Carcinoma, Anaplastic
Article | Year |
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Alternative Promoters of
Topics: Azacitidine; Carcinoma; Cell Line, Tumor; CpG Islands; DNA Methylation; Humans; Luciferases | 2022 |
Multiple keratoacanthomas in a patient with myelodysplastic syndrome.
Topics: Aclarubicin; Administration, Topical; Antineoplastic Agents; Azacitidine; Carcinoma; Female; Humans; Imiquimod; Keratoacanthoma; Middle Aged; Myelodysplastic Syndromes | 2021 |
The effect of EBV on WIF1, NLK, and APC gene methylation and expression in gastric carcinoma and nasopharyngeal cancer.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Genes, APC; Herpesvirus 4, Human; Humans; Intracellular Signaling Peptides and Proteins; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Repressor Proteins; Stomach Neoplasms | 2017 |
Epigenetic control of endothelin-1 axis affects invasiveness of breast carcinoma cells with bone tropism.
Topics: Azacitidine; Bone Neoplasms; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Movement; Collagen; Dactinomycin; DNA Methylation; Drug Combinations; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Laminin; Mutation; Neoplasm Invasiveness; Peptides, Cyclic; Proteoglycans; Proto-Oncogene Protein c-ets-1; Receptor, Endothelin A; RNA Stability; RNA, Messenger; Transcription, Genetic | 2013 |
Latent transforming growth factor β-binding protein 4 is downregulated in esophageal cancer via promoter methylation.
Topics: Azacitidine; Base Sequence; Binding Sites; Carcinoma; Cell Line, Tumor; Cell Movement; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Order; Humans; Latent TGF-beta Binding Proteins; Neoplasm Staging; Promoter Regions, Genetic; Protein Binding; Transcription Factors; Transforming Growth Factor beta1 | 2013 |
Identification of genes specifically methylated in Epstein-Barr virus-associated gastric carcinomas.
Topics: Aged; Azacitidine; Carcinoma; Cell Line, Tumor; Cytoskeletal Proteins; Decitabine; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Epstein-Barr Virus Infections; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Homeodomain Proteins; Humans; Hydroxamic Acids; Male; Microfilament Proteins; Middle Aged; Neoplasm Proteins; Nerve Tissue Proteins; Nuclear Proteins; Oncogene Proteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Transcription Factors; Tumor Protein p73; Tumor Suppressor Proteins | 2013 |
Aberrant CpG island methylation of PTEN is an early event in nasopharyngeal carcinoma and a potential diagnostic biomarker.
Topics: Azacitidine; Base Sequence; Biomarkers, Tumor; Carcinoma; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Mutation; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; PTEN Phosphohydrolase; RNA, Messenger; Sequence Analysis, DNA | 2014 |
Identification of a novel methylated gene in nasopharyngeal carcinoma: TTC40.
Topics: Animals; Azacitidine; Carcinoma; Cell Line, Tumor; CpG Islands; Cytoskeletal Proteins; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Humans; Mice; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Proteins; Promoter Regions, Genetic; Proteins; Xenograft Model Antitumor Assays | 2014 |
Involvement of microRNA-24 and DNA methylation in resistance of nasopharyngeal carcinoma to ionizing radiation.
Topics: Animals; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cluster Analysis; Decitabine; Disease Models, Animal; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Male; Mice; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Radiation Tolerance; Radiation, Ionizing; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Kank1 reexpression induced by 5-Aza-2'-deoxycytidine suppresses nasopharyngeal carcinoma cell proliferation and promotes apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytoskeletal Proteins; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Real-Time Polymerase Chain Reaction; Tumor Suppressor Proteins | 2015 |
Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma; Case-Control Studies; Cell Proliferation; Cells, Cultured; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha Chains; Integrins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Nasopharynx; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Wnt Proteins | 2015 |
Modifying effects of 5-azacytidine on metal-containing proteins profile in Guerin carcinoma with different sensitivity to cytostatics.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cytostatic Agents; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Metalloproteins; Promoter Regions, Genetic; Proteome; Proteomics; Rats | 2016 |
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents; Azacitidine; Brain Neoplasms; Caco-2 Cells; Carcinoma; Colorectal Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Peptides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2008 |
Retinoic acid receptor beta2 re-expression and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Organ Specificity; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Thyroid Gland; Thyroid Neoplasms; Transfection | 2008 |
Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Lung Neoplasms | 2009 |
BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas.
Topics: Alternative Splicing; Azacitidine; Breast Neoplasms; Carcinoma; CCCTC-Binding Factor; Cell Line, Tumor; Decitabine; DNA-Binding Proteins; Exons; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Polymerase Chain Reaction; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution | 2010 |
Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6.
Topics: Azacitidine; Carcinogenicity Tests; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Immunohistochemistry; Inflammation Mediators; Interleukin-6; Neoplasm Metastasis; Promoter Regions, Genetic; Up-Regulation | 2010 |
MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression.
Topics: Azacitidine; Carcinoma; Cell Growth Processes; Cell Line, Tumor; Cytidine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-myc; Transfection; Up-Regulation | 2011 |
Seladin-1 expression is regulated by promoter methylation in adrenal cancer.
Topics: Adrenal Gland Neoplasms; Azacitidine; Carcinoma; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Nerve Tissue Proteins; Oxidoreductases Acting on CH-CH Group Donors; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Time Factors | 2010 |
Promoter hypomethylation contributes to the expression of MUC3A in cancer cells.
Topics: 5' Flanking Region; Azacitidine; Carcinoma; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Mucin-3; RNA, Messenger | 2010 |
Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Apoptosis Regulatory Proteins; Azacitidine; Carcinoma; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Mice; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Polymerase Chain Reaction; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; RNA, Messenger; Time Factors; Transfection; Tumor Suppressor Proteins; Young Adult | 2010 |
TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma.
Topics: Azacitidine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Epigenesis, Genetic; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glycoproteins; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; RNA, Messenger | 2010 |
Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells.
Topics: Azacitidine; Caco-2 Cells; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Cytochrome P-450 CYP3A; Decitabine; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Calcitriol; Receptors, Steroid | 2011 |
Down-regulation of NDRG2 gene expression in human colorectal cancer involves promoter methylation and microRNA-650.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Molecular Sequence Data; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2011 |
Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells.
Topics: Adenocarcinoma, Follicular; Azacitidine; Butyrates; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Screening Assays, Antitumor; Drug Synergism; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Neoplasm Proteins; rap GTP-Binding Proteins; rap1 GTP-Binding Proteins; RNA, Small Interfering; Thyroid Neoplasms; Up-Regulation | 2011 |
Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer.
Topics: Adult; Aged; Apoptosis Regulatory Proteins; Azacitidine; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Thyroid Cancer, Papillary; Thyroid Neoplasms; Trans-Activators; Transcription Factors | 2011 |
DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Carcinoma; Cisplatin; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Molecular Targeted Therapy; Multivariate Analysis; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Stomach Neoplasms; Treatment Outcome; Tumor Stem Cell Assay | 2011 |
Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.
Topics: Azacitidine; Cadherins; Carcinoma; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Neoplasm Invasiveness; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Tumor Suppressor Protein p53 | 2011 |
The DNA methylome of benign and malignant parathyroid tumors.
Topics: Adenoma; Azacitidine; Carcinoma; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Parathyroid Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 2011 |
DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Cadherins; Carcinoma; Cell Cycle Checkpoints; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Endometrial Neoplasms; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Mice; Mice, Nude; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Transplantation, Heterologous; Valproic Acid | 2012 |
Transcriptional silencing of the inhibin-α gene in human gastric carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Inhibins; Loss of Heterozygosity; Promoter Regions, Genetic; Sequence Analysis, DNA; Stomach Neoplasms; Transcription, Genetic | 2012 |
5-aza-2'-deoxycytidine improves the sensitivity of endometrial cancer cells to progesterone therapy.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Apoptosis; Azacitidine; Carcinoma; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Decitabine; Drug Synergism; Drug Therapy, Combination; Endometrial Neoplasms; Female; Humans; Medroxyprogesterone Acetate; Neoplasm Invasiveness; Receptors, Progesterone | 2012 |
LTBP-2 confers pleiotropic suppression and promotes dormancy in a growth factor permissive microenvironment in nasopharyngeal carcinoma.
Topics: Azacitidine; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Latent TGF-beta Binding Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neovascularization, Pathologic; Promoter Regions, Genetic; Tumor Microenvironment; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor A | 2012 |
Genomic methylation profiling combined with gene expression microarray reveals the aberrant methylation mechanism involved in nasopharyngeal carcinoma taxol resistance.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Azacitidine; Carcinoma; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Profiling; Genomics; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel | 2012 |
5-aza-2'-deoxycytidine has minor effects on differentiation in human thyroid cancer cell lines, but modulates genes that are involved in adaptation in vitro.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Carcinoma; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Survival; Decitabine; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Oligonucleotide Array Sequence Analysis; Thyroid Gland; Thyroid Neoplasms; Vorinostat | 2013 |
DNA methylation of RUNX3 in papillary thyroid cancer.
Topics: Azacitidine; Biomarkers, Tumor; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; Gene Expression; Humans; Thyroid Cancer, Papillary; Thyroid Neoplasms | 2012 |
Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinsing fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patient.
Topics: Azacitidine; Carcinoma; Case-Control Studies; Decitabine; DNA; DNA Methylation; DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; Humans; Mouth; Nasopharyngeal Neoplasms; Nuclear Proteins; Pharynx; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Sulfites; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma.
Topics: Adult; Aged; Azacitidine; Base Sequence; Carcinoma; Chromosomes, Human, Pair 3; CpG Islands; Cytoskeletal Proteins; Decitabine; DNA Methylation; DNA Primers; Enzyme Inhibitors; Genes, Tumor Suppressor; Humans; Middle Aged; Molecular Sequence Data; Mutagens; Mutation; Nasopharyngeal Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Sulfites; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Epigenetic inactivation of RASSF1A in head and neck cancer.
Topics: Azacitidine; Carcinoma; Cell Line, Tumor; Decitabine; DNA; DNA Methylation; Down-Regulation; Head and Neck Neoplasms; Humans; Microsatellite Repeats; Papillomaviridae; Point Mutation; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Isoforms; RNA; Sequence Analysis, DNA; Sulfites; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2003 |
Promoter methylation of cyclin D2 gene in gastric carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; CpG Islands; Cyclin D2; Cyclins; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Models, Genetic; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms | 2003 |
Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Carcinoma, Large Cell; Case-Control Studies; Caspase 8; Caspases; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Cell Cycle Proteins; Cerebellum; Child; Child, Preschool; Cohort Studies; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Gene Silencing; Genes, Tumor Suppressor; Histone-Lysine N-Methyltransferase; Humans; Immunoglobulins; Infant; Infant, Newborn; Kruppel-Like Transcription Factors; Medulloblastoma; Membrane Proteins; Middle Aged; Nuclear Proteins; Promoter Regions, Genetic; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Protein p14ARF; Tumor Suppressor Proteins | 2004 |
Human PinX1, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma.
Topics: Azacitidine; Carcinoma; Cell Cycle Proteins; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Gastrointestinal Neoplasms; Gene Expression; Humans; Mutation, Missense; Polymorphism, Genetic; Promoter Regions, Genetic; RNA, Messenger; Sequence Analysis, DNA; Telomerase; Tumor Suppressor Proteins | 2004 |
The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.
Topics: Alleles; Animals; Azacitidine; Base Sequence; Carcinoma; Cell Line; Cell Line, Tumor; Cell Transformation, Viral; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Deletion; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Mice; Mice, Nude; Molecular Sequence Data; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protein Binding; Stress, Physiological; Tumor Suppressor Proteins | 2004 |
Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites.
Topics: Azacitidine; Breast Neoplasms; Carcinoma; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Humans; Nucleic Acid Amplification Techniques; Promoter Regions, Genetic | 2004 |
Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma; Cell Differentiation; Cell Line, Tumor; Colon; Colorectal Neoplasms; Disease Progression; DNA Methylation; DNA Primers; DNA-Binding Proteins; Female; Humans; Immunohistochemistry; Inhibitor of Differentiation Protein 2; Male; Middle Aged; Models, Genetic; Neoplasms; Polymerase Chain Reaction; Prognosis; Repressor Proteins; Risk; RNA, Messenger; Sequence Analysis, DNA; Sulfites; Time Factors; Transcription Factors | 2004 |
Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma; Carcinoma, Renal Cell; Colonic Neoplasms; Decitabine; DNA Methylation; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Isoenzymes; Kidney Neoplasms; Promoter Regions, Genetic; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2005 |
Loss of caspase-1 gene expression in human gastric carcinomas and cell lines.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Caspase 1; Decitabine; DNA Methylation; Female; Gene Expression Profiling; Histones; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Prognosis; Stomach Neoplasms; Survival Analysis; Tumor Cells, Cultured | 2005 |
Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Carcinoma, Non-Small-Cell Lung; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulins; Lung Neoplasms; Membrane Proteins; Microfilament Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2006 |
Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation.
Topics: Azacitidine; Cadherins; Carcinoma; Cell Movement; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Esophageal Neoplasms; Gene Silencing; Genes, Tumor Suppressor; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protocadherins; Sequence Deletion; Transcription, Genetic | 2006 |
Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Blotting, Western; Carcinoma; Carrier Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; DNA, Complementary; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Signal Transduction; Transfection; Wnt Proteins | 2006 |
Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing.
Topics: Animals; Azacitidine; Blotting, Western; Carcinoma; Cell Line; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epigenesis, Genetic; Fibroblasts; Gene Silencing; Histones; Humans; Kinetics; Lung Neoplasms; Lysine; Methyltransferases; Mice; Nickel; Trace Elements; Transgenes | 2006 |
RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; Thyroid Neoplasms; Transcription Factors | 2006 |
Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.
Topics: Azacitidine; Breast Neoplasms; Carcinoma; Cell Adhesion; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulins; Membrane Proteins; Microfilament Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sulfites; Tumor Suppressor Proteins | 2007 |
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.
Topics: Adaptor Proteins, Signal Transducing; Animals; Azacitidine; Biomarkers, Tumor; Carcinoma; Cell Line; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Repressor Proteins; Tumor Suppressor Proteins; Wnt1 Protein | 2007 |
Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma.
Topics: Azacitidine; Base Sequence; Carcinoma; Cell Line, Tumor; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lactoferrin; Loss of Heterozygosity; Male; Middle Aged; Molecular Sequence Data; Mutation; Nasopharyngeal Neoplasms; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.
Topics: Azacitidine; Carcinoma; Cell Proliferation; Colorectal Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Humans; Immunohistochemistry; Promoter Regions, Genetic; Receptors, N-Methyl-D-Aspartate; Tissue Array Analysis | 2008 |
Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Line, Tumor; Chromosomes, Human, Pair 19; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; GTP-Binding Protein gamma Subunits; Humans; Loss of Heterozygosity; Male; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Prognosis; RNA, Messenger | 2008 |
Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.
Topics: Azacitidine; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Checkpoint Kinase 2; Codon, Nonsense; Colorectal Neoplasms; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, cdc; Genes, p53; Humans; Male; Neoplasm Proteins; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2009 |
Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Carcinoma; Cell Adhesion Molecules; Cell Line, Tumor; Cell Nucleus; DNA Methylation; DNA-Cytosine Methylases; Down-Regulation; Epithelial Cell Adhesion Molecule; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Time Factors; Transcription, Genetic; Up-Regulation | 2008 |
Sequential combination of pyrazofurin and 5-azacytidine in patients with acute myelocytic leukemia and carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Amides; Azacitidine; Carcinoma; Carcinoma, Small Cell; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Lung Neoplasms; Male; Middle Aged; Pyrazoles; Ribonucleosides; Ribose | 1981 |
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas.
Topics: Azacitidine; Base Sequence; Cadherins; Carcinoma; DNA Primers; DNA, Neoplasm; Gene Expression; Genes, Regulator; Genes, Tumor Suppressor; Humans; Methylation; Molecular Sequence Data; Neoplasm Invasiveness; Oligodeoxyribonucleotides; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1995 |
Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Base Pair Mismatch; Carcinoma; Carrier Proteins; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Mutational Analysis; DNA Repair; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Microsatellite Repeats; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1999 |
Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells.
Topics: Azacitidine; Blotting, Southern; Carcinoma; Chromosome Mapping; CpG Islands; Cyclooxygenase 2; Decitabine; DNA Methylation; Enzyme Induction; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Isoenzymes; Membrane Proteins; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma.
Topics: Alleles; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Genes, p53; Humans; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells.
Topics: Azacitidine; Cadherins; Carcinoma; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Esophageal Neoplasms; Humans; Promoter Regions, Genetic; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Carcinoma; Chromosome Deletion; Chromosomes, Human, Pair 17; Cohort Studies; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Follow-Up Studies; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, p53; Humans; Kruppel-Like Transcription Factors; Loss of Heterozygosity; Neoplasm Proteins; Prognosis; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Transcription Factors; Tumor Cells, Cultured | 2001 |
Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines.
Topics: Azacitidine; Burkitt Lymphoma; Carcinoma; Cell Differentiation; CpG Islands; DNA Methylation; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, MHC Class II; Genes, Reporter; HLA-DR Antigens; Humans; Interferon-gamma; Melanoma; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Signal Transduction; Trans-Activators; Transfection; Tumor Cells, Cultured | 2002 |
Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.
Topics: Animals; Azacitidine; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Drosophila melanogaster; Drosophila Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Kidney Neoplasms; Loss of Heterozygosity; Lung Neoplasms; Mutation, Missense; Nerve Tissue Proteins; Promoter Regions, Genetic; Receptors, Immunologic; Roundabout Proteins; Sequence Homology, Nucleic Acid; Tumor Cells, Cultured | 2002 |
Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; Down-Regulation; Enzyme Inhibitors; Humans; Microsatellite Repeats; Mutation; Neoplasm Invasiveness; Neoplasm Staging; O(6)-Methylguanine-DNA Methyltransferase; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Stomach; Stomach Neoplasms; Sulfites; Survival Rate; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Phase II study of 5-aza-2'-deoxycytidine in advanced ovarian carcinoma. The EORTC Early Clinical Trials Group.
Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Carcinoma; Decitabine; Drug Evaluation; Female; Humans; Middle Aged; Ovarian Neoplasms | 1990 |