azacitidine and Carcinogenesis

azacitidine has been researched along with Carcinogenesis in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's30 (85.71)24.3611
2020's5 (14.29)2.80

Authors

AuthorsStudies
Cheong, HT; Jung, BD; Kim, DY; Lee, R; Park, J; Ra, CS; Rhee, KJ1
Fu, Y; Hu, M; Ji, J; Jiang, C; Li, L; Nie, Q; Xu, H; Zhang, B; Zhou, X1
Chen, J; Chen, Z; Chi, J; Deng, M; Hu, J; Huang, L; Li, J; Li, Q; Luo, Z; Tao, K; Wang, G; Wang, L; Wang, Z; Zhang, H; Zhou, C1
Chen, N; Cheng, L; Dai, L; Deng, H; Dong, Z; Fang, C; Fu, J; Ji, Y; Li, J; Liu, Y; Shi, G; Su, X; Wang, H; Wang, W; Yang, Y; Yu, Y; Zhang, H; Zhang, S1
Albulescu, A; Anton, G; Badiu, CV; Bostan, M; Botezatu, A; Dobrescu, R; Fudulu, A; Grancea, C; Huica, I; Iancu, IV; Manda, DA; Mihaila, M; Plesa, A; Vladoiu, SV1
Demehri, S; Ghim, SJ; Ha, T; Jenson, AB; Joh, JJ; Khanal, S; Redman, RA; Strickley, JD1
Bai, Y; Chang, D; Li, M; Liu, C; Lv, D; Sun, G; Zhang, X1
Evers, BM; Kim, JT; Weiss, HL1
Chen, Q; Hu, YH; Li, XM; Li, XN; Lin, C; Lu, YX; Zhang, F; Zhang, JM; Zhang, W; Zhang, WJ1
Belardelli, F; Buoncervello, M; Canini, I; Capone, I; De Angelis, M; Del Vecchio, G; Fragale, A; Gabriele, L; Giuliani, C; Leone, C; Licursi, V; Negri, R; Parlato, S; Presutti, C; Romagnoli, G; Toschi, E1
Arentsen-Peters, TCJM; Baruchel, A; Danen-van Oorschot, AA; de Haas, V; Fornerod, M; Larmonie, NSD; Obulkasim, A; Pieters, R; Reinhardt, D; Sonneveld, E; Trka, J; Valerio, D; van den Heuvel-Eibrink, MM; Zimmermann, M; Zwaan, CM1
Amarante-Mendes, GP; Calle, Y; Castro, FA; De Carvalho, DD; Hamerschlak, N; Jacysyn, JF; Jones, GE; Pagnano, KB; Pereira, WO; Ribeiro, BF; Sardinha, LR; Zanichelli, MA; Zenteno, ME1
Barros-Silva, D; Carneiro, I; Carvalho, AL; Costa-Pinheiro, P; Duarte, H; Evangelista, AF; Graça, I; Henrique, R; Jerónimo, C; Marques, MM; Martins, AT; Oliveira, J; Sousa, EJ1
Gailhouste, L; Hatada, I; Liew, LC; Nakagama, H; Ochiya, T; Tanaka, Y; Yasukawa, K1
He, X; Li, S; Pei, L; Ren, G; Sun, R; Xiang, Q; Xiang, T1
Alibés, A; Alonso, S; Fece de la Cruz, F; González, B; Samuelsson, JK1
Aumann, K; Daskalakis, M; Erlacher, M; Flotho, C; Gallego-Villar, L; Hartmann, M; Krombholz, CF; Lipka, DB; Niemeyer, CM; Panda, PK; Plass, C; Sahoo, SS; Wlodarski, MW1
Cui, Y; Ding, M; Gao, Y; Li, X; Li, Y; Singh, N; Tian, R; Wu, X; Yang, Y1
Brock, MV; Guo, M; Herman, JG; Licchesi, JD; Liu, X; Pei, X; Yang, Y; Yue, W; Zhang, X1
Akiyama, Y; Hashimoto, Y; Yuasa, Y1
Brewer, MA; Meng, F; Sun, G; Yu, Y; Zhong, M1
Bai, R; Feng, G; Song, M; Yuan, H; Zhang, J; Zhang, Y; Zheng, J1
Chen, X; Liu, Y; Long, Q; Meng, S; Ren, K; Song, N; Xie, Y; Zhao, X1
Cho, YG; Han, J; Han, JY; Hong, SH; Hwang, JA; Kim, DH; Kim, Y; Kim, YH; Lee, J; Lee, YS; Shim, YM1
Yang, WT; Zheng, PS1
Bai, SY; Jiao, F; Ma, Y; Wang, J; Wang, X; Yan, ZH; Yu, Y; Yue, Z1
Abba, MC; Cattaneo, ER; Coleman, RA; Garcia-Fabiani, MB; Gonzalez-Baro, MR; Lacunza, E; Montanaro, MA; Pellon-Maison, M; Quiroga, IY; Soler-Gerino, MC1
Chen, WZ; Chen, XY; Huang, SH; Liu, JM; Liu, ZL; Long, XH; Peng, AF; Zhang, ZH; Zhou, YF1
Fu, X; Han, W; Li, X; Mei, Q; Nie, J1
Acun, T; Arango, D; Demir, K; Oztas, E; Yakicier, MC1
Gao, D; Guo, M; Herman, JG1
Cao, B; Chen, R; Di, C; Guo, M; Lu, Y; Lu, ZJ; Song, N; Yang, Y; Zhang, M1
Fan, Y; Feng, Y; Kelly, K; Li, C; Li, L; Mu, J; Oberst, M; Peng, W; Ren, G; Tao, Q; Xiang, T; Ying, Y1
Chang, KW; Chiang, WF; Chu, TH; Gong, NR; Lin, SC; Liu, CJ; Wu, CH; Yang, CC1
D'Alessandro, AM; Di Clemente, L; Di Pasquale, B; Dolo, V; Festuccia, C; Gravina, GL; Mancini, A; Marampon, F; Muzi, P; Ranieri, G1

Reviews

2 review(s) available for azacitidine and Carcinogenesis

ArticleYear
Decitabine: a promising epi-immunotherapeutic agent in solid tumors.
    Expert review of clinical immunology, 2015, Volume: 11, Issue:3

    Topics: Animals; Azacitidine; Carcinogenesis; Clinical Trials as Topic; Decitabine; DNA Methylation; DNA Modification Methylases; Humans; Immunotherapy; Neoplasms; Tumor Escape

2015
The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carcinogenesis; CpG Islands; Decitabine; DNA Damage; DNA Methylation; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Drug Resistance, Neoplasm; Epigenesis, Genetic; Fluorouracil; Humans; Molecular Targeted Therapy; Neoplasms; Prognosis; Promoter Regions, Genetic; Tumor Suppressor Proteins

2016

Other Studies

33 other study(ies) available for azacitidine and Carcinogenesis

ArticleYear
5-Azacytidine (5-aza) Induces p53-associated Cell Death Through Inhibition of DNA Methyltransferase Activity in Hep3B and HT-29 Cells.
    Anticancer research, 2023, Volume: 43, Issue:2

    Topics: Azacitidine; Carcinogenesis; Cell Death; Cell Line, Tumor; DNA; DNA Methylation; DNA Modification Methylases; Genes, p53; HT29 Cells; Humans; Tumor Suppressor Protein p53

2023
WIF1 promoter hypermethylation induce endometrial carcinogenesis through the Wnt/β-catenin signaling pathway.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2023, Volume: 90, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Azacitidine; beta Catenin; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Decitabine; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Wnt Signaling Pathway

2023
AGR2 is controlled by DNMT3a-centered signaling module and mediates tumor resistance to 5-Aza in colorectal cancer.
    Experimental cell research, 2019, 12-01, Volume: 385, Issue:1

    Topics: Azacitidine; Caco-2 Cells; Carcinogenesis; Cell Line; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; HT29 Cells; Humans; Mucoproteins; Oncogene Proteins; Prognosis; Promoter Regions, Genetic; Signal Transduction; Up-Regulation

2019
Temporal DNA methylation pattern and targeted therapy in colitis-associated cancer.
    Carcinogenesis, 2020, 04-22, Volume: 41, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Azoxymethane; bcl-Associated Death Protein; Carcinogenesis; Cell Line, Tumor; Colitis; Colon; Colonoscopy; Colorectal Neoplasms; Decitabine; Disease Models, Animal; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Male; Mice; Molecular Targeted Therapy; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Up-Regulation

2020
Alterations of regulatory factors and DNA methylation pattern in thyroid cancer.
    Cancer biomarkers : section A of Disease markers, 2020, Volume: 28, Issue:2

    Topics: Adenocarcinoma, Follicular; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Azacitidine; Biomarkers, Tumor; Carcinogenesis; Cell Line, Tumor; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Epigenesis, Genetic; Feasibility Studies; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Mixed Function Oxygenases; Promoter Regions, Genetic; Proto-Oncogene Proteins; Sensitivity and Specificity; Thyroid Cancer, Papillary; Thyroid Gland; Thyroid Neoplasms; Young Adult

2020
Human papillomavirus-positivity is associated with EREG down-regulation and promoter hypermethylation in head and neck squamous cell carcinoma.
    Experimental and molecular pathology, 2020, Volume: 117

    Topics: Alphapapillomavirus; Azacitidine; Carcinogenesis; Cell Line, Tumor; Decitabine; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Epiregulin; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Squamous Cell Carcinoma of Head and Neck

2020
Hypermethylation of miRNA-589 promoter leads to upregulation of HDAC5 which promotes malignancy in non-small cell lung cancer.
    International journal of oncology, 2017, Volume: 50, Issue:6

    Topics: Aged; Animals; Azacitidine; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Male; Mice; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Promoter Regions, Genetic; Xenograft Model Antitumor Assays

2017
Diverse expression patterns and tumorigenic role of neurotensin signaling components in colorectal cancer cells.
    International journal of oncology, 2017, Volume: 50, Issue:6

    Topics: Adaptor Proteins, Vesicular Transport; Azacitidine; Carcinogenesis; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Promoter Regions, Genetic; Receptors, Neurotensin; Signal Transduction

2017
Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer.
    Oncotarget, 2017, Jul-11, Volume: 8, Issue:28

    Topics: Animals; Azacitidine; Carcinogenesis; Cell Movement; Cell Proliferation; Colonic Neoplasms; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Low Density Lipoprotein Receptor-Related Protein-6; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Staging; RNA, Small Interfering; Tumor Suppressor Proteins; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2017
Antitumor Effects of Epidrug/IFNα Combination Driven by Modulated Gene Signatures in Both Colorectal Cancer and Dendritic Cells.
    Cancer immunology research, 2017, Volume: 5, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinogenesis; Cell Line, Tumor; Colorectal Neoplasms; Dendritic Cells; Depsipeptides; Gene Expression Regulation, Neoplastic; Humans; Interferon Regulatory Factor-7; Interferon Regulatory Factors; Interferon-alpha; Interferon-gamma; Nitric Oxide Synthase Type II; Receptors, Cytokine; Receptors, Interferon; Signal Transduction

2017
MN1 overexpression is driven by loss of DNMT3B methylation activity in inv(16) pediatric AML.
    Oncogene, 2018, 01-04, Volume: 37, Issue:1

    Topics: Adolescent; Azacitidine; Carcinogenesis; Cell Line, Tumor; Child; Child, Preschool; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Exons; Female; Gene Expression Regulation, Leukemic; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Trans-Activators; Tumor Suppressor Proteins

2018
BCR-ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy.
    Cell death & disease, 2017, 10-12, Volume: 8, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Carcinogenesis; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Promoter Regions, Genetic; Protein Kinase Inhibitors; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Wiskott-Aldrich Syndrome Protein

2017
MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis.
    Cell death & disease, 2018, 02-07, Volume: 9, Issue:2

    Topics: Aged; Azacitidine; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cohort Studies; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Regulatory Networks; Humans; Male; MicroRNAs; Middle Aged; Phenotype; Promoter Regions, Genetic; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-myc; Response Elements; RNA, Messenger; Signal Transduction; Up-Regulation

2018
Differentiation Therapy by Epigenetic Reconditioning Exerts Antitumor Effects on Liver Cancer Cells.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2018, 07-05, Volume: 26, Issue:7

    Topics: Animals; Azacitidine; Carcinogenesis; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocytes; Humans; Liver; Liver Neoplasms; Mice; Mice, Nude

2018
KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer.
    International journal of oncology, 2018, Volume: 53, Issue:3

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Middle Aged; Promoter Regions, Genetic; Signal Transduction; Stomach; Stomach Neoplasms; Transcription Factors; Tumor Suppressor Proteins; Up-Regulation

2018
Epigenetic and transcriptional dysregulation of VWA2 associated with a MYC-driven oncogenic program in colorectal cancer.
    Scientific reports, 2018, 07-23, Volume: 8, Issue:1

    Topics: Aged; Azacitidine; Biomarkers, Tumor; Calcium-Binding Proteins; Carcinogenesis; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genetic Loci; Histone Code; Humans; Introns; Male; Middle Aged; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; RNA, Messenger; Transcription, Genetic; Up-Regulation; Wnt Proteins

2018
Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia.
    Leukemia, 2019, Volume: 33, Issue:7

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinogenesis; Humans; Leukemia, Myelomonocytic, Juvenile; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Neoplastic Stem Cells; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Promoter hypermethylation of SOX11 promotes the progression of cervical cancer in vitro and in vivo.
    Oncology reports, 2019, Volume: 41, Issue:4

    Topics: Adult; Azacitidine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cervix Uteri; CpG Islands; Disease Progression; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Promoter Regions, Genetic; SOXC Transcription Factors; Tumor Suppressor Proteins; Up-Regulation; Uterine Cervical Neoplasms

2019
Epigenetic regulation of the Wnt signaling inhibitor DACT2 in human hepatocellular carcinoma.
    Epigenetics, 2013, Volume: 8, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Animals; Apoptosis; Azacitidine; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Carcinogenesis; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Decitabine; Epigenesis, Genetic; Female; G2 Phase Cell Cycle Checkpoints; Heterografts; Humans; Liver Neoplasms; Male; Methylation; Mice, Nude; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Transcription Factor 4; Transcription Factors; Wnt Signaling Pathway

2013
Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Azacitidine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Methyl-CpG-Binding Protein 2; MicroRNAs; Nerve Tissue Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Stomach Neoplasms; Transfection

2013
Inhibition of DNA methyltransferases, histone deacetylases and lysine-specific demethylase-1 suppresses the tumorigenicity of the ovarian cancer ascites cell line SKOV3.
    International journal of oncology, 2013, Volume: 43, Issue:2

    Topics: Acetylation; Animals; Ascites; Azacitidine; Cadherins; Carcinogenesis; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Histones; Humans; Hydroxamic Acids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C3H; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Nuclear Proteins; Ovarian Neoplasms; Spheroids, Cellular; Tumor Cells, Cultured; Twist-Related Protein 1

2013
DNA methylation of trefoil factor 1 (TFF1) is associated with the tumorigenesis of gastric carcinoma.
    Molecular medicine reports, 2014, Volume: 9, Issue:1

    Topics: Apoptosis; Azacitidine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Gene Expression Regulation; Humans; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Trefoil Factor-1; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2014
Expression loss and revivification of RhoB gene in ovary carcinoma carcinogenesis and development.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Carcinogenesis; Case-Control Studies; Cystadenoma, Serous; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Hydroxamic Acids; Methyltransferases; Neoplasm Staging; Ovarian Neoplasms; Ovary; rhoB GTP-Binding Protein

2013
Epigenetic inactivation of heparan sulfate (glucosamine) 3-O-sulfotransferase 2 in lung cancer and its role in tumorigenesis.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Adult; Azacitidine; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Knockdown Techniques; Gene Silencing; Humans; Lung Neoplasms; Male; Neoplasm Invasiveness; Phenotype; Prognosis; Promoter Regions, Genetic; Proportional Hazards Models; Sulfotransferases

2013
Promoter hypermethylation of KLF4 inactivates its tumor suppressor function in cervical carcinogenesis.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Azacitidine; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cisplatin; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Promoter Regions, Genetic; Protein Biosynthesis; Transcription, Genetic; Tumor Suppressor Proteins; Uterine Cervical Neoplasms

2014
DNA methylation of heparanase promoter influences its expression and associated with the progression of human breast cancer.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Carcinogenesis; Cell Proliferation; Decitabine; Disease Progression; DNA Methylation; Gene Expression Regulation, Neoplastic; Glucuronidase; Humans; MCF-7 Cells; Neoplasm Invasiveness; Promoter Regions, Genetic

2014
Glycerol-3-phosphate acyltranferase-2 behaves as a cancer testis gene and promotes growth and tumorigenicity of the breast cancer MDA-MB-231 cell line.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Azacitidine; Breast Neoplasms; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Computer Simulation; Decitabine; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Glycerol-3-Phosphate O-Acyltransferase; Humans; Male; Mice; RNA, Small Interfering; Testis

2014
Demethylation-mediated miR-129-5p up-regulation inhibits malignant phenotype of osteogenic osteosarcoma by targeting Homo sapiens valosin-containing protein (VCP).
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:5

    Topics: Adenosine Triphosphatases; Azacitidine; Carcinogenesis; Cell Cycle Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Osteosarcoma; Signal Transduction; Valosin Containing Protein

2015
PTPRD is homozygously deleted and epigenetically downregulated in human hepatocellular carcinomas.
    Omics : a journal of integrative biology, 2015, Volume: 19, Issue:4

    Topics: Azacitidine; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Homozygote; Humans; Hydroxamic Acids; Liver Neoplasms; Microarray Analysis; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Sequence Deletion

2015
Systematic study of novel lncRNAs in different gastrointestinal cancer cells.
    Discovery medicine, 2016, Volume: 21, Issue:115

    Topics: Apoptosis; Azacitidine; Biomarkers, Tumor; Carcinogenesis; Cell Cycle; Cell Line, Tumor; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Real-Time Polymerase Chain Reaction; RNA, Long Noncoding; Sequence Analysis, RNA; Signal Transduction; Up-Regulation

2016
DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells.
    Oncotarget, 2016, Oct-25, Volume: 7, Issue:43

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Azacitidine; Breast; Breast Neoplasms; Carcinogenesis; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; CpG Islands; Decitabine; DNA Demethylation; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Glycogen Synthase Kinase 3; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Wnt Signaling Pathway

2016
miR-370 modulates insulin receptor substrate-1 expression and inhibits the tumor phenotypes of oral carcinoma.
    Oral diseases, 2013, Volume: 19, Issue:6

    Topics: Azacitidine; Carcinogenesis; Carcinoma, Squamous Cell; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cells, Cultured; Decitabine; DNA Modification Methylases; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Insulin Receptor Substrate Proteins; Keratinocytes; MicroRNAs; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Staging; Oncogene Protein v-akt; RNA, Small Interfering; TOR Serine-Threonine Kinases

2013
Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells.
    Oncology reports, 2013, Volume: 29, Issue:3

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinogenesis; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Epithelial Cells; Gene Expression; Glutathione S-Transferase pi; Humans; Male; Phenotype; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms

2013