azacitidine and Cancer of Ovary

azacitidine has been researched along with Cancer of Ovary in 113 studies

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (5.31)18.2507
2000's40 (35.40)29.6817
2010's61 (53.98)24.3611
2020's6 (5.31)2.80

Authors

AuthorsStudies
Bowden, NA; van der Westhuizen, A; Wong-Brown, MW1
Abbady, AQ; Alghamian, Y; Murad, H; Soukkarieh, C1
Alvarez Secord, A; Armstrong, DK; Azab, M; Banerjee, S; Basu, B; Birrer, MJ; Blagden, SP; Braly, P; Fleming, GF; Ghamande, S; Hall, GD; Hao, Y; Hirte, HW; Jueliger, S; Keer, H; Kristeleit, R; Markham, MJ; Matei, D; Matulonis, UA; McGuire, WP; Naim, S; Nemunaitis, J; Nephew, KP; Oganesian, A; Oza, AM; Provencher, DM; Roman, LD; Schwartz, B1
Chhabra, R; Guergues, J; Hill, R; Nadeau, OW; Nanjundan, M; Rockfield, S; Stevens, SM1
Fang, F; Nephew, KP; Ozes, A; Wang, W1
Arthofer, E; Baylin, SB; Chiappinelli, KB; Cox, O; Diab, N; Gomez, S; Grundy, EE; Hadley, M; Kanholm, T; McDonald, JI; Rentia, U; Strick, R; Strissel, PL; Topper, MJ; Wang, T; Xing, X; Yu, A1
Arend, RC; Buchsbaum, DJ; Forero, A; Katre, A; Londoño, A; Meza-Perez, S; Norian, LA; Peabody, JE; Randall, TD; Smith, HJ; Straughn, JM; Turner, TB1
Bachman, KE; Baylin, SB; Bhargava, V; Chiappinelli, KB; Cowley, GS; Hung, CF; Li, H; Lim, M; Mathios, D; Murphy, LM; Shih, IM; Stone, ML; Strick, R; Strissel, PL; Topper, MJ; Travers, ME; Wang, TL; Wiehagen, KR; Zahnow, CA1
Baylin, SB; DeWitt, AK; Jones, PA; Liang, G; Liu, M; Madaj, ZB; Ohtani, H; Thomas, SL; Zhou, W1
Matei, D; Mitra, AK; Mitra, S; Nephew, KP; Wang, Y; Zong, X1
Bachman, KE; Baylin, SB; Brown, SM; Casero, RA; Dunworth, M; Foley, JR; Holbert, CE; Stone, ML; Travers, M; Wiehagen, KR; Zahnow, CA1
Cui, G; Fan, WS; Fu, XY; Guan, Z; Huang, K; Li, J; Li, LA; Li, YL; Meng, YG; Sun, L; Wang, SJ; Yan, ZF; Yang, YZ; You, YQ1
Brewer, MA; Meng, F; Sun, G; Yu, Y; Zhong, M2
Ornstein, DL; Preis, M1
Cheng, W; Chu, Y; Jiang, Y; Tang, W; Wan, Y; Zhang, L1
Angioli, R; Barbosa, A; Begum, S; Brait, M; de Graeff, P; Fazio, VM; Hoque, MO; Loyo, M; Maldonado, L; Marchionni, L; Noordhuis, M; Noordhuis, MG; Poeta, ML; Rabitti, C; Sidransky, D; van der Zee, AG; Wisman, GB1
Chen, X; Liu, Y; Long, Q; Meng, S; Ren, K; Song, N; Xie, Y; Zhao, X1
Cao, X; Chen, X; Liu, M; Tao, G; Xie, W; Zhou, F1
Akers, SN; Batt, CA; Beck, A; Gnjatic, S; Griffiths, EA; James, SR; Karpf, AR; Lele, S; Matsuzaki, J; Mhawech-Fauceglia, P; Miliotto, A; Miller, A; Odunsi, K; Ritter, G; Tsuji, T; Zhang, W1
Brüning, A; Buchholtz, ML; Jückstock, J; Mylonas, I1
Lin, L; Liu, PS; Ma, XP; Ma, YC; Wu, Y; Zhang, X1
Benmaamar, R1
Appleton, K; Brown, R; Gabra, H; Glasspool, RM; Gore, ME; Halford, SE; Hall, GD; Kaye, S; Mackean, M; McNeish, IA; Paul, J; Pledge, S; Rustin, GJ; Ullah, R; Walker, J; Wilson, RH1
Ahn, JH; Choi, EN; Choi, HJ; Ju, W; Kim, NH; Lyu, D; Sung, HY1
Chen, Z; Li, J; Sheng, X; Tan, L; Yang, L; Zhao, Q; Zhou, Y1
Ahn, JH; Choi, EN; Ju, W; Lyu, D; Park, AK; Sung, HY1
Chen, JY; Hong, CQ; Huang, P; Wu, MY; Wu, X; You, YJ; Zhang, F; Zhuang, YX1
Fang, F; Li, M; Matei, D; Nephew, KP; Pilrose, J; Shen, C; Wang, Y; Wulfridge, P; Zuo, Q1
Cardenas, H; Condello, S; Fang, F; Liu, Y; Matei, D; Nephew, KP; Segar, M; Taverna, P; Wang, Y1
Brennan, K; Fedier, A; Hacker, NF; Heinzelmann-Schwarz, VA; Hitchins, MP; Jacob, F; Nixdorf, S; Ward, R1
Chan, MW; Fang, YC; Hsu, MM; Huang, PY; Lee, CI; Lee, YC1
Azab, M; Choy, G; Fang, F; Lyons, J; Matei, D; Miller, DF; Munck, J; Nephew, KP; Pawelczak, KS; Pilrose, J; Tang, J; Taverna, P; Turchi, JJ; VanderVere-Carozza, P; Wagner, M; Wang, Y1
Ahn, JH; Ju, W; Sung, HY1
Cardenas, H; Lee, J; Liu, Y; Matei, D; Nephew, KP; Segar, M; Vieth, E1
Dong, R; He, X; Li, J; Qiu, H; Wang, Y; Yu, J1
Collamat-Lai, G; Griffiths, EA; James, SR; Karpf, AR; Matsuzaki, J; Paluch, BE; Srivastava, P; Taverna, P1
Chen, M; Fu, X; Han, W; Meng, Y; Nie, J; Wang, X; Wang, Y; Zhang, Y1
Chang, YM; Khabele, D; Kim, JW; Schreiber, SL; Shamji, AF; Stewart, ML; Tamayo, P; Wang, S; Wilson, AJ1
Amoozgar, Z; Goldberg, MS; Huang, J; Orsulic, S; Saleh, MH; Wang, L; Xing, D1
Akers, SN; Barger, CJ; Karpf, AR; Link, PA; Mhawech-Fauceglia, P; Miller, A; Odunsi, K; Zhang, W1
Bapat, SA; Chandra, N; Singh, AK1
Akman, B; Baylin, SB; Beckmann, MW; Budhu, S; Buhu, S; Chan, TA; Chiappinelli, KB; Cope, LM; Desrichard, A; Hein, A; Henke, C; Li, H; Makarov, V; Merghoub, T; Mergoub, T; Pardoll, DM; Rote, NS; Slamon, DJ; Snyder, A; Strick, R; Strissel, PL; Wolchok, JD; Zahnow, CA1
Li, J; Sheng, X; Tan, L; Wang, Z; Zhou, D; Zhou, Y1
Benson, EA; Liu, Y; Matei, D; Nephew, KP; Skaar, TC1
Baggerly, K; Bast, RC; Bedi, A; Das, P; Fishman, D; Liu, J; Lu, Z; Mao, W; Marquez, RT; Wang, Y; Yang, H; Yu, Y1
Qiu, SC; Wang, YZ1
Chen, P; Li, Q; Wu, X; Zhao, Y1
Alkema, NG; de Jong, S; Hoekman, RL; Klip, HG; Meersma, GJ; Tomar, T; van der Zee, AG; Wisman, GB1
Adair, SJ; Hogan, KT1
Cui, J; Shen, L; Yu, H; Zhang, A; Zhang, H; Zhang, S1
Dai, DQ; Guo, KJ; Meng, CF1
Fu, S; Hu, W; Kavanagh, JJ; Li, Y; Shen, DY1
Dai, Y; Desai, N; Kwong, J; Mok, SC; Motamed, K; Ramalingam, P; Said, N; Socha, MJ; Trieu, V1
Brown, R; Finn, P; Plumb, JA; Steele, N1
Bhat, G; Liu, L; Tollefsbol, TO; Yap, OW1
Baba, T; Berchuck, A; Bland, AE; Fujii, S; Huang, Z; Lee, PS; Murphy, SK; Secord, AA; Teaberry, VS; Whitaker, RS1
Wei, L; Yu, H; Zhang, A; Zhang, L; Zhang, S1
Li, N; Qu, PP; Shi, Z1
Chan, MW; Chao, TK; Chen, LY; Chou, JL; Davuluri, RV; Deatherage, DE; Hartman-Frey, C; Hsiao, SH; Huang, TH; Huang, YW; Kuo, CT; Lai, HC; Lai, YH; Liao, YP; Lin, HJ; Nephew, KP; Su, HY; Tai, CK; Yan, PS; Yang, HW1
Balch, C; Breen, T; Fang, F; Kulesavage, C; Li, L; Matei, DE; Nephew, KP; Schilder, J; Shen, C; Snyder, AJ; Zhang, S1
James, SR; Jin, B; Karpf, AR; Odunsi, K; Song, C; Woloszynska-Read, A1
Bast, RC; Coleman, RL; Fu, S; Gershenson, DM; Hennessy, BT; Hu, W; Iyer, R; Kavanagh, JJ; Kurzrock, R; Levenback, CF; Markman, M; Sood, AK; Wolf, JK1
Auersperg, N; Cheng, JC; Leung, PC1
Ahmed, AA; Bast, RC; Bornmann, WG; Chen, MY; Hennessey, V; Liao, WS; Lu, Z; Rosner, GL; Washington, MN; Yu, Y1
Dong, R; Pu, H; Qiu, H; Yu, J; Zhu, J1
Bhattacharyya, B; Hallett, M; Han, ZG; Huang, J; Stefanska, B; Suderman, M; Szyf, M1
Alvarez Secord, A; Darcy, KM; Havrilesky, LJ; Huang, Z; Hutson, A; Jewell, EL; Lee, PS; Markman, M; Muggia, F; Murphy, SK1
Blanco-Fernández, A; Dempsey, E; Harvey, DJ; Madden, SF; Mariño, K; McCann, A; Peracaula, R; Pérez-Garay, M; Rudd, PM; Saldova, R; Struwe, WB; Watson, JA1
Brown, R; Dai, W; Plumb, JA; Rizzo, S; Siddiq, A; Steele, NL; van der Zee, A; Walley, AJ; Wilhelm-Benartzi, CS; Zeller, C1
Arnold, A; Berry, WA; Fang, F; Huang, T; Matei, D; Nephew, KP; Schilder, J; Shen, C; Zeng, Y1
Daudi, S; Kim, KM; Kim, MJ; Lee, SY; Miliotto, A; Odunsi, K; Old, L; Song, MH1
Calonne, E; Delbecque, K; Delvenne, P; Deplus, R; Ennaji, MM; Fuks, F; Guenin, S; Kridelka, F; Krusy, N; Lampe, X; Mouallif, M1
Godwin, AK; Guo, S; Liu, M1
Di, W; Gu, L; Zhang, S; Zhu, J1
Gao, X; Han, D; Huang, H; Li, F; Ma, N; Qiao, Y; Wang, D; Wang, L; Wang, X; Wu, G; Xiang, Y; Zhang, G; Zhang, Y; Zhao, R; Zhou, J1
Godwin, AK; Gupta, A; Liu, J; Lu, A; Vanderveer, L1
Bates, PA; Brown, I; Contreras-Moreira, B; Gabra, H; Li, L; Massie, CE; Miller, EP; Miller, J; Rabiasz, GJ; Scott, D; Sellar, GC; Smyth, JF; Stronach, EA; Watt, KP; Williams, AR1
Facchinetti, F; Mezzanzanica, D; Modena, P; Pilotti, S; Radice, MT; Sozzi, G; Testi, MA1
Burrows, JF; Chanduloy, S; Donaghy, P; Godwin, AK; Johnston, PG; McIlhatton, MA; Nagar, H; Price, J; Russell, SE; Yeates, K1
Becker, M; Ebert, MP; Göhring, UJ; Hoffmann, J; Moser, N; Pur, S; Schöndorf, T; Weisshaar, MP1
Assaly, M; Benz, A; Cerato, C; Desmond, JC; Greloz, V; Hermeking, H; Herrmann, F; Koeffler, HP; Lodygin, D; Mhawech, P; Schwaller, J1
Kohno, T; Nishioka, M; Ochiai, K; Okamoto, A; Otsuka, A; Tanaka, T; Yanaihara, N; Yokota, J1
Imura, M; Maekita, T; Miyamoto, K; Nakagawa, S; Takada, T; Taketani, Y; Tsao, SW; Ushijima, T; Yagi, Y; Yasugi, T; Yoshino, O1
Chan, KY; Cheung, AN; Chiu, PM; Ip, P; Khoo, US; Ngan, HY; Shen, DH; Xue, WC1
Haller, G; Horak, P; Horvat, R; Krainer, M; Pils, D; Pribill, I; Roessler, M; Tomek, S; Zeillinger, R; Zielinski, C1
Balch, C; Craft, T; Huang, TH; Nephew, KP; Skalnik, DG; Yan, P; Young, S1
Brown, R; Chan, MW; Huang, TH; Liu, JC; Liyanarachchi, S; Matei, DE; Nephew, KP; Wang, Z; Wei, SH; Wen, P; Yan, PS1
Cheng, X; Liu, J; Mei, FC; Young, TW1
Li, M; Lu, S; Wang, H; Wang, Z; Zhang, Y1
Ichimura, S; Mori, A; Nakazawa, K; Okochi-Takada, E; Ushijima, T; Wakabayashi, M; Yasugi, T1
Diamandis, EP; Pampalakis, G; Sotiropoulou, G1
Hongmei, L; Xiaoyan, X; Yuecheng, Y1
Dong, WH; He, XH; Huang, ZJ; Li, M; Li, XY; Wang, H; Wang, XY; Wang, ZH1
Calin, GA; Croce, CM; Di Leva, G; Godwin, AK; Iliopoulos, D; Negrini, M; Nicoloso, MS; Petrocca, F; Qin, HR; Shimizu, M; Trapasso, F; Vecchione, A; Wojcik, SE; Yendamuri, S1
Connolly, DC; Dinulescu, DM; Donahoe, PK; Halpern, EF; MacLaughlin, DT; Pearsall, LA; Pieretti-Vanmarcke, R; Seiden, MV1
Benigno, BB; Bowen, NJ; Dickerson, EB; Matyunina, LV; McDonald, JF; Menendez, L; Polavarapu, N; Walker, D1
Akahira, J; Ito, K; Moriya, T; Niikura, H; Okamura, K; Sakuma, M; Sasano, H; Yaegashi, N1
Aletti, G; Chien, J; Molina, J; Narita, K; Pan, Y; Qian, X; Roberts, LR; Scheerer, M; Shridhar, V; Staub, J1
D'Souza, T; Honda, H; Ji, H; Morin, PJ; Pazin, MJ1
Cortese, R; de Leij, LFMH; Jeltsch, A; Kiss, A; McLaughlin, PMJ; Monami, A; Raskó, T; Rots, MG; Ruiters, MHJ; Ślaska-Kiss, K; van der Gun, BTF; Wasserkort, R; Weinhold, E1
Izutsu, N; Maesawa, C; Masuda, T; Oikawa, H; Shibazaki, M; Shoji, T; Sugiyama, T1
Benigno, BB; Matyunina, LV; McDonald, JF; Menendez, L; Totten, KA; Walker, LD1
Blessing, JA; Look, KY; Manetta, A1
Parekh, HK; Simpkins, H1
Götzinger, N; Mueller-Lantzsch, N; Roemer, K; Sauter, M1
Brown, R; Illand, M; MacKean, MJ; Strathdee, G1
Brown, R; Kaye, SB; Plumb, JA; Sludden, J; Strathdee, G1
Avula, R; Bible, KC; Hartmann, LC; Huang, H; Kalli, K; Kaufmann, SH; Lee, YK; Shridhar, V; Smith, DI; Staub, J1
Arnold, JM; Chenevix-Trench, G; Cummings, M; Purdie, D1
Aird, RE; Chen, H; Cummings, J; Jodrell, DI; Morris, RE; Muir, M; Ritchie, AA; Sadler, PJ1
Kanoh, H; Makino, T; Matsui, Y; Okudaira, Y1
Cavalli, F; Renard, J; Sessa, C; Stoter, G; ten Bokkel Huinink, W1

Trials

9 trial(s) available for azacitidine and Cancer of Ovary

ArticleYear
A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 03-01, Volume: 26, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gemcitabine; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Patient Safety; Polyethylene Glycols; Survival Rate; Topotecan; Treatment Outcome

2020
Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer.
    Cancer immunology research, 2014, Volume: 2, Issue:1

    Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cancer Vaccines; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Decitabine; DNA Methylation; Doxorubicin; Epigenesis, Genetic; Female; Gene Expression; Humans; Immunity, Humoral; Immunotherapy, Active; Long Interspersed Nucleotide Elements; Membrane Proteins; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polyethylene Glycols; T-Lymphocyte Subsets; Treatment Outcome

2014
A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent, partially platinum-sensitive ovarian cancer.
    British journal of cancer, 2014, Apr-15, Volume: 110, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; MutL Protein Homolog 1; Neoplasm Recurrence, Local; Nuclear Proteins; Ovarian Neoplasms; Platinum

2014
Low Dose Decitabine Combined with Taxol and Platinum Chemotherapy to Treat Refractory/Recurrent Ovarian Cancer: An Open-Label, Single-Arm, Phase I/II Study.
    Current protein & peptide science, 2015, Volume: 16, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Decitabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Ovarian Neoplasms; Paclitaxel; Platinum; Recurrence; Safety

2015
Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Carboplatin; Decitabine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ovarian Neoplasms; Pilot Projects; Prognosis; Survival Rate; Young Adult

2015
A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer.
    Cancer, 2010, Sep-01, Volume: 116, Issue:17

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Decitabine; DNA Methylation; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Platinum Compounds

2010
Phase 1b-2a study to reverse platinum resistance through use of a hypomethylating agent, azacitidine, in patients with platinum-resistant or platinum-refractory epithelial ovarian cancer.
    Cancer, 2011, Apr-15, Volume: 117, Issue:8

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Carcinoma, Ovarian Epithelial; Disease-Free Survival; DNA Methylation; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms

2011
Epigenetic resensitization to platinum in ovarian cancer.
    Cancer research, 2012, May-01, Volume: 72, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Decitabine; Disease-Free Survival; DNA Methylation; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Peritoneal Neoplasms

2012
A phase II study of fazarabine in patients with advanced ovarian cancer. A Gynecologic Oncology Group study.
    American journal of clinical oncology, 1995, Volume: 18, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Female; Humans; Infusions, Intravenous; Neoplasm Recurrence, Local; Ovarian Neoplasms; Treatment Outcome

1995

Other Studies

104 other study(ies) available for azacitidine and Cancer of Ovary

ArticleYear
Sequential azacitidine and carboplatin induces immune activation in platinum-resistant high-grade serous ovarian cancer cell lines and primes for checkpoint inhibitor immunotherapy.
    BMC cancer, 2022, Jan-24, Volume: 22, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Cell Growth Processes; Cell Line, Tumor; DNA Methylation; Female; Humans; Immune Checkpoint Inhibitors; Immunity; Neoplasm Grading; Neoplasms, Cystic, Mucinous, and Serous; Ovarian Neoplasms; Signal Transduction; Up-Regulation

2022
Investigation of role of CpG methylation in some epithelial mesenchymal transition gene in a chemoresistant ovarian cancer cell line.
    Scientific reports, 2022, 05-06, Volume: 12, Issue:1

    Topics: Azacitidine; Cell Line, Tumor; Cisplatin; CpG Islands; DNA Methylation; Drug Resistance, Neoplasm; Epithelial Cell Adhesion Molecule; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms

2022
Global miRNA/proteomic analyses identify miRNAs at 14q32 and 3p21, which contribute to features of chronic iron-exposed fallopian tube epithelial cells.
    Scientific reports, 2021, 03-18, Volume: 11, Issue:1

    Topics: Azacitidine; Biomarkers, Tumor; Cell Line, Transformed; Cell Transformation, Neoplastic; Down-Regulation; Epithelial Cells; Fallopian Tubes; Female; Ferric Compounds; Gene Expression Profiling; Genetic Loci; Humans; MDS1 and EVI1 Complex Locus Protein; MicroRNAs; Ovarian Neoplasms; Proteome; Proteomics; Quaternary Ammonium Compounds; Transcriptome; Transfection; Vorinostat

2021
Targeting Ovarian Cancer Stem Cells by Dual Inhibition of HOTAIR and DNA Methylation.
    Molecular cancer therapeutics, 2021, Volume: 20, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Humans; Mice; Neoplastic Stem Cells; Ovarian Neoplasms; Peptide Nucleic Acids; RNA, Long Noncoding; Xenograft Model Antitumor Assays

2021
Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a
    Cancer research, 2021, 10-15, Volume: 81, Issue:20

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Cell Proliferation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Ovarian Neoplasms; Repetitive Sequences, Nucleic Acid; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2021
Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth.
    Oncotarget, 2017, Jul-04, Volume: 8, Issue:27

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Benzamides; Cell Line, Tumor; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Drug Synergism; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens Class II; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Mice; Ovarian Neoplasms; Panobinostat; Pyridines; RNA, Messenger; Transcription, Genetic; Tumor Burden; Xenograft Model Antitumor Assays

2017
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 12-19, Volume: 114, Issue:51

    Topics: Animals; Antineoplastic Agents, Immunological; Azacitidine; Cell Line, Tumor; Disease Models, Animal; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Immunomodulation; Interferon Type I; Mice; Ovarian Neoplasms; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays

2017
Dual Inhibition of DNA and Histone Methyltransferases Increases Viral Mimicry in Ovarian Cancer Cells.
    Cancer research, 2018, 10-15, Volume: 78, Issue:20

    Topics: Antineoplastic Agents; Azacitidine; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Methylation; Drug Synergism; Endogenous Retroviruses; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Ovarian Neoplasms; Prognosis; Sequence Analysis, RNA; Transcriptional Activation

2018
IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells.
    JCI insight, 2018, 12-06, Volume: 3, Issue:23

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Azacitidine; Cell Line, Tumor; Cytokines; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Drug Therapy; Epigenomics; Female; Humans; Immunotherapy; Interleukin-6; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neoplastic Stem Cells; Ovarian Neoplasms; Platinum; Retinal Dehydrogenase; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment; Up-Regulation

2018
DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer.
    Cancer research, 2019, 07-01, Volume: 79, Issue:13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cystadenocarcinoma, Serous; Disease Models, Animal; Eflornithine; Female; Immunity, Innate; Macrophages; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; Polyamines; Tumor Cells, Cultured; Tumor Microenvironment

2019
STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer.
    Oncology reports, 2013, Volume: 30, Issue:1

    Topics: Acetylation; Adult; Azacitidine; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; rho GTP-Binding Proteins; STAT3 Transcription Factor

2013
Inhibition of DNA methyltransferases, histone deacetylases and lysine-specific demethylase-1 suppresses the tumorigenicity of the ovarian cancer ascites cell line SKOV3.
    International journal of oncology, 2013, Volume: 43, Issue:2

    Topics: Acetylation; Animals; Ascites; Azacitidine; Cadherins; Carcinogenesis; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Histones; Humans; Hydroxamic Acids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C3H; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Nuclear Proteins; Ovarian Neoplasms; Spheroids, Cellular; Tumor Cells, Cultured; Twist-Related Protein 1

2013
The different faces of myelodysplasia in peripheral blood granulocytes.
    American journal of hematology, 2014, Volume: 89, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Chemotherapy, Adjuvant; Decitabine; Female; Granulocytes; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary; Ovarian Neoplasms; Remission Induction

2014
Transcription factor WT1 and promoter CpG hypomethylation coactivate HOXA10 expression in ovarian cancer.
    Current pharmaceutical design, 2014, Volume: 20, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; CpG Islands; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Homeobox A10 Proteins; Homeodomain Proteins; Humans; Middle Aged; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Small Interfering; Transfection; Up-Regulation; WT1 Proteins

2014
Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Adult; Aged; Azacitidine; Base Sequence; Cohort Studies; Decitabine; Disease Progression; DNA Methylation; DNA Primers; Female; Humans; Middle Aged; Nerve Growth Factors; Ovarian Neoplasms; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Ubiquitin Thiolesterase

2013
Expression loss and revivification of RhoB gene in ovary carcinoma carcinogenesis and development.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Carcinogenesis; Case-Control Studies; Cystadenoma, Serous; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Hydroxamic Acids; Methyltransferases; Neoplasm Staging; Ovarian Neoplasms; Ovary; rhoB GTP-Binding Protein

2013
Methylation of OPCML promoter in ovarian cancer tissues predicts poor patient survival.
    Clinical chemistry and laboratory medicine, 2014, Volume: 52, Issue:5

    Topics: Adult; Age Factors; Aged; Azacitidine; Biomarkers; Cell Adhesion Molecules; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; GPI-Linked Proteins; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; RNA; Sequence Analysis, DNA

2014
Epigenetic silencing of the LDOC1 tumor suppressor gene in ovarian cancer cells.
    Archives of gynecology and obstetrics, 2014, Volume: 290, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Cell Line; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Middle Aged; Ovarian Neoplasms; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

2014
Aberrant methylation of RASSF2A in tumors and plasma of patients with epithelial ovarian cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:3

    Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Tumor Suppressor Proteins

2014
Epigenetic modification boosts ovarian cancer vaccination.
    The Lancet. Oncology, 2014, Volume: 15, Issue:2

    Topics: Antigens, Neoplasm; Azacitidine; Cancer Vaccines; Carcinoma, Ovarian Epithelial; Combined Modality Therapy; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Treatment Outcome

2014
Aberrant DNA methylation in the IFITM1 promoter enhances the metastatic phenotype in an intraperitoneal xenograft model of human ovarian cancer.
    Oncology reports, 2014, Volume: 31, Issue:5

    Topics: Animals; Antigens, Differentiation; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Xenograft Model Antitumor Assays

2014
Promoter hypermethylation influences the suppressive role of maternally expressed 3, a long non-coding RNA, in the development of epithelial ovarian cancer.
    Oncology reports, 2014, Volume: 32, Issue:1

    Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; RNA, Long Noncoding; Tumor Suppressor Protein p53

2014
Aberrant hypomethylation-mediated AGR2 overexpression induces an aggressive phenotype in ovarian cancer cells.
    Oncology reports, 2014, Volume: 32, Issue:2

    Topics: Animals; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mucoproteins; Neoplasm Metastasis; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Oncogene Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Proteins

2014
Clinical importance and therapeutic implication of E-cadherin gene methylation in human ovarian cancer.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:8

    Topics: Adult; Aged; Azacitidine; Cadherins; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Molecular Targeted Therapy; Ovarian Neoplasms; Promoter Regions, Genetic; Young Adult

2014
Decitabine reactivated pathways in platinum resistant ovarian cancer.
    Oncotarget, 2014, Jun-15, Volume: 5, Issue:11

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression; Gene Expression Profiling; Humans; Ovarian Neoplasms

2014
Epigenetic targeting of ovarian cancer stem cells.
    Cancer research, 2014, Sep-01, Volume: 74, Issue:17

    Topics: Aldehyde Dehydrogenase; Animals; Azacitidine; Carboplatin; Cell Differentiation; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Ovarian Neoplasms

2014
Expression of GBGT1 is epigenetically regulated by DNA methylation in ovarian cancer cells.
    BMC molecular biology, 2014, Oct-07, Volume: 15

    Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; N-Acetylgalactosaminyltransferases; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic

2014
FT-IR microspectrometry reveals the variation of membrane polarizability due to epigenomic effect on epithelial ovarian cancer.
    International journal of molecular sciences, 2014, Oct-08, Volume: 15, Issue:10

    Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Membrane; Chromatography, High Pressure Liquid; CpG Islands; Decitabine; Deoxycytidine Monophosphate; DNA Methylation; DNA, Ribosomal; Epigenomics; Female; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Spectroscopy, Fourier Transform Infrared

2014
The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Dec-15, Volume: 20, Issue:24

    Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cisplatin; Disease Models, Animal; DNA Adducts; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Ovarian Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2014
DNA hypomethylation-mediated overexpression of carbonic anhydrase 9 induces an aggressive phenotype in ovarian cancer cells.
    Yonsei medical journal, 2014, Volume: 55, Issue:6

    Topics: Animals; Azacitidine; Carbonic Anhydrases; Carcinoma, Ovarian Epithelial; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Phenotype; Promoter Regions, Genetic; RNA, Messenger

2014
TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells.
    Epigenetics, 2014, Volume: 9, Issue:11

    Topics: Antigens, CD; Azacitidine; Cadherins; Cell Line, Tumor; Collagen Type I; Collagen Type I, alpha 1 Chain; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Enzyme Inhibitors; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; Transforming Growth Factor beta

2014
Frequent Loss of NISCH Promotes Tumor Proliferation and Invasion in Ovarian Cancer via Inhibiting the FAK Signal Pathway.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:5

    Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Female; Focal Adhesion Kinase 1; Humans; Imidazoline Receptors; Intracellular Signaling Peptides and Proteins; Loss of Heterozygosity; Neoplasm Invasiveness; Neoplasm Transplantation; Ovarian Neoplasms; Promoter Regions, Genetic; Signal Transduction

2015
Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts.
    Epigenetics, 2015, Volume: 10, Issue:3

    Topics: Animals; Antigens, Neoplasm; Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; DNA Methylation; Enzyme Inhibitors; Heterografts; Humans; Methyltransferases; Mice, SCID; Neoplasm Transplantation; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; T-Lymphocytes

2015
KRAS Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine.
    Cancer research, 2015, Jul-15, Volume: 75, Issue:14

    Topics: Animals; Azacitidine; Biomarkers, Tumor; Cystadenocarcinoma, Serous; Decitabine; Drug Resistance, Neoplasm; Female; Genes, ras; Humans; Mice; Mice, Nude; Mice, Transgenic; Mutation; Ovarian Neoplasms; Prognosis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
Decitabine Enhances Lymphocyte Migration and Function and Synergizes with CTLA-4 Blockade in a Murine Ovarian Cancer Model.
    Cancer immunology research, 2015, Volume: 3, Issue:9

    Topics: Animals; Antineoplastic Agents; Ascitic Fluid; Azacitidine; CD8-Positive T-Lymphocytes; Cell Movement; Cell Transformation, Neoplastic; CTLA-4 Antigen; Cytokines; Decitabine; Female; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Killer Cells, Natural; Lymph Nodes; Lymphocytes, Tumor-Infiltrating; Mice; Ovarian Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2015
DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer.
    Epigenetics, 2015, Volume: 10, Issue:8

    Topics: Aged; Antigens, Neoplasm; Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger

2015
Evaluation of Epigenetic Drug Targeting of Heterogenous Tumor Cell Fractions Using Potential Biomarkers of Response in Ovarian Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Nov-15, Volume: 21, Issue:22

    Topics: Animals; Azacitidine; Benzamidines; Biomarkers, Tumor; Curcumin; Cytochrome P-450 Enzyme System; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Hydroxamic Acids; Molecular Targeted Therapy; Ovarian Neoplasms; Piperazines; Proteins; Retinoid X Receptor gamma

2015
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
    Cell, 2015, Aug-27, Volume: 162, Issue:5

    Topics: Animals; Azacitidine; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; Endogenous Retroviruses; Female; Humans; Immunotherapy; Interferon Type I; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; RNA, Double-Stranded

2015
[Reversal effect of 5-aza-2-deoxycytidine on the maternally expressed gene 3 promoter hypermethylation and its inhibitory effect on the proliferation of epithelial ovarian cancer cells].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2015, Volume: 37, Issue:5

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Ovarian Epithelial; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Female; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger

2015
NDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms.
    Oncotarget, 2016, Jan-19, Volume: 7, Issue:3

    Topics: Animals; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Movement; CpG Islands; Decitabine; DNA Methylation; Epithelium; Female; Focal Adhesion Kinase 1; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Loss of Heterozygosity; Mice; Mice, Nude; Nerve Tissue Proteins; Nuclear Proteins; Ovarian Neoplasms; Ovary; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins pp60(c-src); rhoA GTP-Binding Protein; Stress Fibers; Tumor Suppressor Proteins

2016
Prediction of key genes in ovarian cancer treated with decitabine based on network strategy.
    Oncology reports, 2016, Volume: 35, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Cell Cycle Proteins; Computational Biology; Cyclin B1; Databases, Genetic; Decitabine; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Interleukin-1beta; Interleukin-2; Microarray Analysis; Nuclear Proteins; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Reverse Transcriptase Polymerase Chain Reaction

2016
Upregulation of p27Kip1 by demethylation sensitizes cisplatin-resistant human ovarian cancer SKOV3 cells.
    Molecular medicine reports, 2016, Volume: 14, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Cisplatin; Cyclin-Dependent Kinase Inhibitor p27; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms

2016
Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways.
    Genome medicine, 2016, 10-20, Volume: 8, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Ovarian Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2016
Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules.
    Cancer immunology, immunotherapy : CII, 2009, Volume: 58, Issue:4

    Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Flow Cytometry; Gene Expression; Histocompatibility Antigens Class I; Humans; Ovarian Neoplasms; Polymerase Chain Reaction; Up-Regulation

2009
Expression and promoter methylation status of mismatch repair gene hMLH1 and hMSH2 in epithelial ovarian cancer.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2008, Volume: 48, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Base Pair Mismatch; Case-Control Studies; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; MutL Protein Homolog 1; MutL Proteins; Neoplasm Proteins; Neoplasm Staging; Nuclear Proteins; Ovarian Neoplasms; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2008
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP].
    Ai zheng = Aizheng = Chinese journal of cancer, 2008, Volume: 27, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; MutL Protein Homolog 1; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger

2008
Azacitidine enhances sensitivity of platinum-resistant ovarian cancer cells to carboplatin through induction of apoptosis.
    American journal of obstetrics and gynecology, 2009, Volume: 200, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Carboplatin; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms

2009
Aberrant promoter methylation of SPARC in ovarian cancer.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Osteonectin; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Analysis; Tumor Cells, Cultured

2009
Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo.
    British journal of cancer, 2009, Mar-10, Volume: 100, Issue:5

    Topics: Acetylation; Adaptor Proteins, Signal Transducing; Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Hydroxamic Acids; Melanoma-Specific Antigens; Mice; Mice, Nude; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009
Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells.
    Anticancer research, 2009, Volume: 29, Issue:1

    Topics: Azacitidine; Cell Growth Processes; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor beta; Female; Histone Acetyltransferases; Humans; Hydroxamic Acids; Ovarian Neoplasms; Promoter Regions, Genetic

2009
Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer.
    International journal of cancer, 2010, Mar-15, Volume: 126, Issue:6

    Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Cell Line, Tumor; Cell Proliferation; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Epithelial Cells; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Membrane Transport Proteins; Molecular Sequence Data; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Promoter Regions, Genetic; Proteolipids; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Survivors

2010
RUNX3 gene methylation in epithelial ovarian cancer tissues and ovarian cancer cell lines.
    Omics : a journal of integrative biology, 2009, Volume: 13, Issue:4

    Topics: Azacitidine; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger

2009
[E-cadherin promoter methylation and demethylation in epithelial ovarian carcinoma cells].
    Zhonghua fu chan ke za zhi, 2009, Volume: 44, Issue:7

    Topics: Azacitidine; Cadherins; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic

2009
Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer.
    Laboratory investigation; a journal of technical methods and pathology, 2010, Volume: 90, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Muscle Proteins; Ovarian Neoplasms; Prognosis; Promoter Regions, Genetic; Proportional Hazards Models; SKP Cullin F-Box Protein Ligases; Smad4 Protein; Taiwan; Transforming Growth Factor beta; Young Adult

2010
BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines.
    Cancer immunity, 2010, Jul-23, Volume: 10

    Topics: Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Organ Specificity; Ovarian Neoplasms; Promoter Regions, Genetic; Transcription Initiation Site

2010
Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.
    Oncogene, 2011, Sep-15, Volume: 30, Issue:37

    Topics: Azacitidine; Cadherins; Carcinoma; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Neoplasm Invasiveness; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Tumor Suppressor Protein p53

2011
Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy.
    Cancer, 2011, Oct-01, Volume: 117, Issue:19

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Azacitidine; Cell Division; Cell Line, Tumor; Cell Proliferation; Decitabine; Drug Synergism; Drug Therapy, Combination; Epigenomics; Female; G2 Phase; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genomic Imprinting; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Transplantation, Heterologous; Vorinostat

2011
SLIT2 is epigenetically silenced in ovarian cancers and suppresses growth when activated.
    Asian Pacific journal of cancer prevention : APJCP, 2011, Volume: 12, Issue:3

    Topics: Apoptosis; Azacitidine; Case-Control Studies; Cell Proliferation; DNA; DNA Methylation; Epigenomics; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Intercellular Signaling Peptides and Proteins; Nerve Tissue Proteins; Ovarian Neoplasms; Ovary; Polymerase Chain Reaction; Promoter Regions, Genetic; Tumor Cells, Cultured; Wound Healing

2011
Definition of the landscape of promoter DNA hypomethylation in liver cancer.
    Cancer research, 2011, Sep-01, Volume: 71, Issue:17

    Topics: Aged; Azacitidine; Breast Neoplasms; Carcinoma, Hepatocellular; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Ovarian Neoplasms; Promoter Regions, Genetic

2011
The regulation of MASPIN expression in epithelial ovarian cancer: association with p53 status, and MASPIN promoter methylation: a gynecologic oncology group study.
    Gynecologic oncology, 2011, Volume: 123, Issue:2

    Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; Serpins; Tumor Suppressor Protein p53

2011
5-AZA-2'-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer.
    Epigenetics, 2011, Volume: 6, Issue:11

    Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Decitabine; Female; Glycoproteins; Glycosylation; Glycosyltransferases; Humans; Methylation; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polysaccharides

2011
Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling.
    Oncogene, 2012, Oct-18, Volume: 31, Issue:42

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cisplatin; Collagen Type I; Collagen Type I, alpha 1 Chain; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Epigenomics; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Midkine; MutL Protein Homolog 1; Nerve Growth Factors; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides

2012
A novel cancer/testis antigen KP-OVA-52 identified by SEREX in human ovarian cancer is regulated by DNA methylation.
    International journal of oncology, 2012, Volume: 41, Issue:3

    Topics: Antibodies, Neoplasm; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Library; Humans; Male; Ovarian Neoplasms; Recombinant Fusion Proteins; RNA, Messenger; Testicular Neoplasms

2012
Aberrant promoter methylation and expression of UTF1 during cervical carcinogenesis.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cervix Uteri; Cluster Analysis; Cytological Techniques; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Neoplasms, Glandular and Epithelial; Neoplastic Stem Cells; Nuclear Proteins; Octamer Transcription Factor-3; Ovarian Neoplasms; Promoter Regions, Genetic; Sequence Analysis, DNA; SOXB1 Transcription Factors; Trans-Activators; Uterine Cervical Neoplasms

2012
Transcriptional regulation of hTREX84 in human cancer cells.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Azacitidine; Base Sequence; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Decitabine; DNA-Binding Proteins; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; RNA-Binding Proteins; Sequence Analysis, DNA; Sulfites; Transcription Factor RelA; Transcription, Genetic

2012
Epigenetic silencing of DKK2 and Wnt signal pathway components in human ovarian carcinoma.
    Carcinogenesis, 2012, Volume: 33, Issue:12

    Topics: Animals; Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Mice; Neoplasm Invasiveness; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Wnt Signaling Pathway

2012
MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine.
    Oncogene, 2014, Jan-16, Volume: 33, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Hep G2 Cells; Humans; Mice; Mice, Nude; MicroRNAs; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Xenograft Model Antitumor Assays

2014
Anticancer efficacy of cisplatin and trichostatin A or 5-aza-2'-deoxycytidine on ovarian cancer.
    British journal of cancer, 2013, Feb-19, Volume: 108, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Cisplatin; Decitabine; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Inbred C3H; Mice, SCID; Ovarian Neoplasms; Spheroids, Cellular; Tumor Cells, Cultured

2013
Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma.
    Cancer research, 2003, Feb-01, Volume: 63, Issue:3

    Topics: Azacitidine; Breast Neoplasms; CpG Islands; Decitabine; DNA Methylation; Epithelial Cells; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Nerve Tissue Proteins; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synucleins; Tumor Cells, Cultured

2003
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.
    Nature genetics, 2003, Volume: 34, Issue:3

    Topics: Animals; Azacitidine; Breast Neoplasms; Carrier Proteins; Case-Control Studies; Cell Adhesion Molecules; Chromosomes, Human, Pair 11; CpG Islands; DNA; DNA Methylation; Enzyme Inhibitors; Female; Genes, Tumor Suppressor; GPI-Linked Proteins; Humans; Loss of Heterozygosity; Mice; Mice, Nude; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neoplasms, Glandular and Epithelial; Nerve Tissue Proteins; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tumor Cells, Cultured

2003
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.
    Oncogene, 2003, Jul-17, Volume: 22, Issue:29

    Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 22; CpG Islands; DNA Methylation; DNA-Binding Proteins; Electron Transport Complex III; Exons; Extrachromosomal Inheritance; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Kruppel-Like Transcription Factors; Molecular Sequence Data; Neoplasm Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Proteins; Repressor Proteins; RNA-Binding Protein EWS; Sarcoma; Soft Tissue Neoplasms; Translocation, Genetic; Tumor Cells, Cultured

2003
Altered expression of the septin gene, SEPT9, in ovarian neoplasia.
    The Journal of pathology, 2003, Volume: 201, Issue:4

    Topics: Adult; Azacitidine; Base Sequence; Cell Line, Tumor; DNA, Circular; Female; Fetus; Gene Expression Regulation, Neoplastic; GTP Phosphohydrolases; Humans; Methylation; Mutation; Ovarian Neoplasms; Protein Splicing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Septins; Transcription, Genetic

2003
Hypermethylation of the PTEN gene in ovarian cancer cell lines.
    Cancer letters, 2004, Apr-30, Volume: 207, Issue:2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Phosphoric Monoester Hydrolases; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins

2004
Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2005, Volume: 18, Issue:3

    Topics: 14-3-3 Proteins; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; CpG Islands; DNA Methylation; Down-Regulation; Endometrial Neoplasms; Exonucleases; Exoribonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mutation; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; RNA, Messenger; Tissue Array Analysis; Tumor Suppressor Protein p53

2005
Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer.
    International journal of cancer, 2004, Oct-20, Volume: 112, Issue:1

    Topics: Azacitidine; Carcinoma, Endometrioid; Case-Control Studies; Chromosomes, Human, Pair 22; Cystadenocarcinoma, Mucinous; Cystadenocarcinoma, Serous; Decitabine; DNA Methylation; DNA Mutational Analysis; Female; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Mutation, Missense; Myosin Heavy Chains; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Tumor Cells, Cultured

2004
Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.
    Cancer science, 2004, Volume: 95, Issue:9

    Topics: Adult; Aged; Azacitidine; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Middle Aged; Ovarian Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wnt Proteins

2004
Epigenetic and genetic alterations of p33ING1b in ovarian cancer.
    Carcinogenesis, 2005, Volume: 26, Issue:4

    Topics: Adenocarcinoma, Clear Cell; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Endometrioid; Case-Control Studies; Cell Cycle Proteins; CpG Islands; Cystadenocarcinoma, Mucinous; Cystadenocarcinoma, Serous; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Immunoenzyme Techniques; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Loss of Heterozygosity; Mutation; Nuclear Proteins; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins

2005
Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer.
    Molecular cancer research : MCR, 2005, Volume: 3, Issue:6

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Cell Line, Tumor; Decitabine; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunohistochemistry; Membrane Glycoproteins; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2005
Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Cytidine; Decitabine; DNA Methylation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Ovarian Neoplasms

2005
Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-15, Volume: 11, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Decitabine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA, Ribosomal; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Multivariate Analysis; Ovarian Neoplasms; Prognosis; RNA, Ribosomal, 18S; RNA, Ribosomal, 28S; Survival Analysis

2005
RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Azacitidine; Cell Adhesion Molecules; Cell Line, Transformed; Cell Transformation, Neoplastic; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Epithelial Cells; Female; Gene Silencing; Genes, ras; GPI-Linked Proteins; Humans; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; Signal Transduction

2006
Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting Fanconi anemia-BRCA pathway.
    Cancer biology & therapy, 2006, Volume: 5, Issue:3

    Topics: Animals; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Fanconi Anemia; Fanconi Anemia Complementation Group F Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

2006
Silencing of the UCHL1 gene in human colorectal and ovarian cancers.
    International journal of cancer, 2006, Sep-15, Volume: 119, Issue:6

    Topics: Azacitidine; Colorectal Neoplasms; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; Tumor Cells, Cultured; Ubiquitin Thiolesterase

2006
The epigenetic basis for the aberrant expression of kallikreins in human cancers.
    Biological chemistry, 2006, Volume: 387, Issue:6

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Male; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms

2006
Clinical evaluation of E-cadherin expression and its regulation mechanism in epithelial ovarian cancer.
    Clinical & experimental metastasis, 2006, Volume: 23, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cadherins; Cell Line, Tumor; DNA Primers; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction

2006
[Disfigurement of p16INK4A gene expression in development of ovarian cancer and the mechanism].
    Zhonghua fu chan ke za zhi, 2006, Volume: 41, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Seeding; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2006
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.
    Cancer research, 2006, Nov-01, Volume: 66, Issue:21

    Topics: ADP-Ribosylation Factors; Apoptosis; Azacitidine; Breast Neoplasms; Cell Proliferation; Decitabine; Down-Regulation; Female; Genes, Tumor Suppressor; Humans; Ovarian Neoplasms

2006
Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Nov-14, Volume: 103, Issue:46

    Topics: Animals; Anti-Mullerian Hormone; Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; Drug Resistance, Neoplasm; Female; Glycoproteins; Humans; Immunoglobulin G; Melphalan; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Receptors, Peptide; Receptors, Transforming Growth Factor beta; Testicular Hormones; Xenograft Model Antitumor Assays

2006
Identification of candidate methylation-responsive genes in ovarian cancer.
    Molecular cancer, 2007, Jan-25, Volume: 6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Ovarian Neoplasms

2007
Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer.
    Cancer science, 2007, Volume: 98, Issue:3

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cyclin D2; Cyclins; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Immunohistochemistry; Ovarian Neoplasms; Prognosis; Promoter Regions, Genetic; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2007
Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance.
    Oncogene, 2007, Jul-26, Volume: 26, Issue:34

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Chromatin; Cisplatin; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Middle Aged; Ovarian Neoplasms; Sulfotransferases

2007
Regulation of the CLDN3 gene in ovarian cancer cells.
    Cancer biology & therapy, 2007, Volume: 6, Issue:11

    Topics: Azacitidine; Binding Sites; Cell Line, Tumor; Claudin-3; Claudin-4; CpG Islands; Decitabine; DNA Methylation; Female; Humans; Hydroxamic Acids; Membrane Proteins; Mutagenesis, Site-Directed; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Sp3 Transcription Factor

2007
Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation.
    International journal of cancer, 2008, Jul-15, Volume: 123, Issue:2

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Carcinoma; Cell Adhesion Molecules; Cell Line, Tumor; Cell Nucleus; DNA Methylation; DNA-Cytosine Methylases; Down-Regulation; Epithelial Cell Adhesion Molecule; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Time Factors; Transcription, Genetic; Up-Regulation

2008
Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells.
    International journal of oncology, 2008, Volume: 32, Issue:6

    Topics: Azacitidine; CpG Islands; Cystadenocarcinoma, Serous; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Ovarian Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Tubulin; Tumor Cells, Cultured

2008
Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors.
    Molecular cancer, 2008, May-22, Volume: 7

    Topics: Adult; Aged; Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; DNA Methylation; Epigenesis, Genetic; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens Class I; HLA Antigens; HLA-G Antigens; Humans; Middle Aged; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transcription Initiation Site

2008
The differential expression of cytokeratin 18 in cisplatin-sensitive and -resistant human ovarian adenocarcinoma cells and its association with drug sensitivity.
    Cancer research, 1995, Nov-15, Volume: 55, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Cisplatin; DNA Damage; Drug Resistance; Female; Humans; Keratins; Ovarian Neoplasms; Tumor Cells, Cultured

1995
Regulation of human endogenous retrovirus-K Gag expression in teratocarcinoma cell lines and human tumours.
    The Journal of general virology, 1996, Volume: 77 ( Pt 12)

    Topics: Azacitidine; Butyrates; Butyric Acid; DNA Methylation; DNA, Viral; Female; Gene Products, gag; Humans; Male; Methylation; Ovarian Neoplasms; Retroelements; Teratocarcinoma; Testicular Neoplasms; Tumor Cells, Cultured

1996
A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer.
    Oncogene, 1999, Apr-08, Volume: 18, Issue:14

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Azacitidine; Base Pair Mismatch; Carrier Proteins; Cisplatin; Cross-Linking Reagents; DNA Methylation; DNA Repair; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic

1999
Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter.
    Cancer research, 2000, Nov-01, Volume: 60, Issue:21

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Base Pair Mismatch; Carboplatin; Carrier Proteins; Cisplatin; Colonic Neoplasms; Dacarbazine; Decitabine; DNA Methylation; DNA Repair; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2000
Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Amino Acid Sequence; Azacitidine; Base Sequence; Chromosome Mapping; Cisplatin; Cloning, Molecular; Decitabine; DNA, Neoplasm; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Humans; In Situ Hybridization, Fluorescence; Loss of Heterozygosity; Molecular Sequence Data; Ovarian Neoplasms; Oximes; Paclitaxel; Piperazines; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Topotecan; Transfection; Tumor Cells, Cultured

2001
Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas.
    British journal of cancer, 2001, Nov-02, Volume: 85, Issue:9

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; DNA Primers; DNA, Neoplasm; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Adhesion Molecule-1; Loss of Heterozygosity; Methylation; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Prognosis; RNA, Messenger; Survival Analysis; Tumor Cells, Cultured

2001
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer.
    British journal of cancer, 2002, May-20, Volume: 86, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Calcium Channel Blockers; Carboplatin; Cisplatin; Decitabine; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Edetic Acid; Female; Humans; Ligands; Mice; Mice, Nude; Neoplasm Proteins; Organometallic Compounds; Ovarian Neoplasms; Ruthenium Compounds; Structure-Activity Relationship; Verapamil; Xenograft Model Antitumor Assays

2002
[Primary culture and characterization of human ovarian surface epithelial cells].
    Nihon Sanka Fujinka Gakkai zasshi, 1990, Volume: 42, Issue:1

    Topics: Adult; Azacitidine; Collagen; Culture Media; Epithelium; Female; Gels; Humans; Middle Aged; Ovarian Neoplasms; Ovary; Tumor Cells, Cultured

1990
Phase II study of 5-aza-2'-deoxycytidine in advanced ovarian carcinoma. The EORTC Early Clinical Trials Group.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Carcinoma; Decitabine; Drug Evaluation; Female; Humans; Middle Aged; Ovarian Neoplasms

1990