azacitidine has been researched along with Cancer of Ovary in 113 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (5.31) | 18.2507 |
2000's | 40 (35.40) | 29.6817 |
2010's | 61 (53.98) | 24.3611 |
2020's | 6 (5.31) | 2.80 |
Authors | Studies |
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Bowden, NA; van der Westhuizen, A; Wong-Brown, MW | 1 |
Abbady, AQ; Alghamian, Y; Murad, H; Soukkarieh, C | 1 |
Alvarez Secord, A; Armstrong, DK; Azab, M; Banerjee, S; Basu, B; Birrer, MJ; Blagden, SP; Braly, P; Fleming, GF; Ghamande, S; Hall, GD; Hao, Y; Hirte, HW; Jueliger, S; Keer, H; Kristeleit, R; Markham, MJ; Matei, D; Matulonis, UA; McGuire, WP; Naim, S; Nemunaitis, J; Nephew, KP; Oganesian, A; Oza, AM; Provencher, DM; Roman, LD; Schwartz, B | 1 |
Chhabra, R; Guergues, J; Hill, R; Nadeau, OW; Nanjundan, M; Rockfield, S; Stevens, SM | 1 |
Fang, F; Nephew, KP; Ozes, A; Wang, W | 1 |
Arthofer, E; Baylin, SB; Chiappinelli, KB; Cox, O; Diab, N; Gomez, S; Grundy, EE; Hadley, M; Kanholm, T; McDonald, JI; Rentia, U; Strick, R; Strissel, PL; Topper, MJ; Wang, T; Xing, X; Yu, A | 1 |
Arend, RC; Buchsbaum, DJ; Forero, A; Katre, A; Londoño, A; Meza-Perez, S; Norian, LA; Peabody, JE; Randall, TD; Smith, HJ; Straughn, JM; Turner, TB | 1 |
Bachman, KE; Baylin, SB; Bhargava, V; Chiappinelli, KB; Cowley, GS; Hung, CF; Li, H; Lim, M; Mathios, D; Murphy, LM; Shih, IM; Stone, ML; Strick, R; Strissel, PL; Topper, MJ; Travers, ME; Wang, TL; Wiehagen, KR; Zahnow, CA | 1 |
Baylin, SB; DeWitt, AK; Jones, PA; Liang, G; Liu, M; Madaj, ZB; Ohtani, H; Thomas, SL; Zhou, W | 1 |
Matei, D; Mitra, AK; Mitra, S; Nephew, KP; Wang, Y; Zong, X | 1 |
Bachman, KE; Baylin, SB; Brown, SM; Casero, RA; Dunworth, M; Foley, JR; Holbert, CE; Stone, ML; Travers, M; Wiehagen, KR; Zahnow, CA | 1 |
Cui, G; Fan, WS; Fu, XY; Guan, Z; Huang, K; Li, J; Li, LA; Li, YL; Meng, YG; Sun, L; Wang, SJ; Yan, ZF; Yang, YZ; You, YQ | 1 |
Brewer, MA; Meng, F; Sun, G; Yu, Y; Zhong, M | 2 |
Ornstein, DL; Preis, M | 1 |
Cheng, W; Chu, Y; Jiang, Y; Tang, W; Wan, Y; Zhang, L | 1 |
Angioli, R; Barbosa, A; Begum, S; Brait, M; de Graeff, P; Fazio, VM; Hoque, MO; Loyo, M; Maldonado, L; Marchionni, L; Noordhuis, M; Noordhuis, MG; Poeta, ML; Rabitti, C; Sidransky, D; van der Zee, AG; Wisman, GB | 1 |
Chen, X; Liu, Y; Long, Q; Meng, S; Ren, K; Song, N; Xie, Y; Zhao, X | 1 |
Cao, X; Chen, X; Liu, M; Tao, G; Xie, W; Zhou, F | 1 |
Akers, SN; Batt, CA; Beck, A; Gnjatic, S; Griffiths, EA; James, SR; Karpf, AR; Lele, S; Matsuzaki, J; Mhawech-Fauceglia, P; Miliotto, A; Miller, A; Odunsi, K; Ritter, G; Tsuji, T; Zhang, W | 1 |
Brüning, A; Buchholtz, ML; Jückstock, J; Mylonas, I | 1 |
Lin, L; Liu, PS; Ma, XP; Ma, YC; Wu, Y; Zhang, X | 1 |
Benmaamar, R | 1 |
Appleton, K; Brown, R; Gabra, H; Glasspool, RM; Gore, ME; Halford, SE; Hall, GD; Kaye, S; Mackean, M; McNeish, IA; Paul, J; Pledge, S; Rustin, GJ; Ullah, R; Walker, J; Wilson, RH | 1 |
Ahn, JH; Choi, EN; Choi, HJ; Ju, W; Kim, NH; Lyu, D; Sung, HY | 1 |
Chen, Z; Li, J; Sheng, X; Tan, L; Yang, L; Zhao, Q; Zhou, Y | 1 |
Ahn, JH; Choi, EN; Ju, W; Lyu, D; Park, AK; Sung, HY | 1 |
Chen, JY; Hong, CQ; Huang, P; Wu, MY; Wu, X; You, YJ; Zhang, F; Zhuang, YX | 1 |
Fang, F; Li, M; Matei, D; Nephew, KP; Pilrose, J; Shen, C; Wang, Y; Wulfridge, P; Zuo, Q | 1 |
Cardenas, H; Condello, S; Fang, F; Liu, Y; Matei, D; Nephew, KP; Segar, M; Taverna, P; Wang, Y | 1 |
Brennan, K; Fedier, A; Hacker, NF; Heinzelmann-Schwarz, VA; Hitchins, MP; Jacob, F; Nixdorf, S; Ward, R | 1 |
Chan, MW; Fang, YC; Hsu, MM; Huang, PY; Lee, CI; Lee, YC | 1 |
Azab, M; Choy, G; Fang, F; Lyons, J; Matei, D; Miller, DF; Munck, J; Nephew, KP; Pawelczak, KS; Pilrose, J; Tang, J; Taverna, P; Turchi, JJ; VanderVere-Carozza, P; Wagner, M; Wang, Y | 1 |
Ahn, JH; Ju, W; Sung, HY | 1 |
Cardenas, H; Lee, J; Liu, Y; Matei, D; Nephew, KP; Segar, M; Vieth, E | 1 |
Dong, R; He, X; Li, J; Qiu, H; Wang, Y; Yu, J | 1 |
Collamat-Lai, G; Griffiths, EA; James, SR; Karpf, AR; Matsuzaki, J; Paluch, BE; Srivastava, P; Taverna, P | 1 |
Chen, M; Fu, X; Han, W; Meng, Y; Nie, J; Wang, X; Wang, Y; Zhang, Y | 1 |
Chang, YM; Khabele, D; Kim, JW; Schreiber, SL; Shamji, AF; Stewart, ML; Tamayo, P; Wang, S; Wilson, AJ | 1 |
Amoozgar, Z; Goldberg, MS; Huang, J; Orsulic, S; Saleh, MH; Wang, L; Xing, D | 1 |
Akers, SN; Barger, CJ; Karpf, AR; Link, PA; Mhawech-Fauceglia, P; Miller, A; Odunsi, K; Zhang, W | 1 |
Bapat, SA; Chandra, N; Singh, AK | 1 |
Akman, B; Baylin, SB; Beckmann, MW; Budhu, S; Buhu, S; Chan, TA; Chiappinelli, KB; Cope, LM; Desrichard, A; Hein, A; Henke, C; Li, H; Makarov, V; Merghoub, T; Mergoub, T; Pardoll, DM; Rote, NS; Slamon, DJ; Snyder, A; Strick, R; Strissel, PL; Wolchok, JD; Zahnow, CA | 1 |
Li, J; Sheng, X; Tan, L; Wang, Z; Zhou, D; Zhou, Y | 1 |
Benson, EA; Liu, Y; Matei, D; Nephew, KP; Skaar, TC | 1 |
Baggerly, K; Bast, RC; Bedi, A; Das, P; Fishman, D; Liu, J; Lu, Z; Mao, W; Marquez, RT; Wang, Y; Yang, H; Yu, Y | 1 |
Qiu, SC; Wang, YZ | 1 |
Chen, P; Li, Q; Wu, X; Zhao, Y | 1 |
Alkema, NG; de Jong, S; Hoekman, RL; Klip, HG; Meersma, GJ; Tomar, T; van der Zee, AG; Wisman, GB | 1 |
Adair, SJ; Hogan, KT | 1 |
Cui, J; Shen, L; Yu, H; Zhang, A; Zhang, H; Zhang, S | 1 |
Dai, DQ; Guo, KJ; Meng, CF | 1 |
Fu, S; Hu, W; Kavanagh, JJ; Li, Y; Shen, DY | 1 |
Dai, Y; Desai, N; Kwong, J; Mok, SC; Motamed, K; Ramalingam, P; Said, N; Socha, MJ; Trieu, V | 1 |
Brown, R; Finn, P; Plumb, JA; Steele, N | 1 |
Bhat, G; Liu, L; Tollefsbol, TO; Yap, OW | 1 |
Baba, T; Berchuck, A; Bland, AE; Fujii, S; Huang, Z; Lee, PS; Murphy, SK; Secord, AA; Teaberry, VS; Whitaker, RS | 1 |
Wei, L; Yu, H; Zhang, A; Zhang, L; Zhang, S | 1 |
Li, N; Qu, PP; Shi, Z | 1 |
Chan, MW; Chao, TK; Chen, LY; Chou, JL; Davuluri, RV; Deatherage, DE; Hartman-Frey, C; Hsiao, SH; Huang, TH; Huang, YW; Kuo, CT; Lai, HC; Lai, YH; Liao, YP; Lin, HJ; Nephew, KP; Su, HY; Tai, CK; Yan, PS; Yang, HW | 1 |
Balch, C; Breen, T; Fang, F; Kulesavage, C; Li, L; Matei, DE; Nephew, KP; Schilder, J; Shen, C; Snyder, AJ; Zhang, S | 1 |
James, SR; Jin, B; Karpf, AR; Odunsi, K; Song, C; Woloszynska-Read, A | 1 |
Bast, RC; Coleman, RL; Fu, S; Gershenson, DM; Hennessy, BT; Hu, W; Iyer, R; Kavanagh, JJ; Kurzrock, R; Levenback, CF; Markman, M; Sood, AK; Wolf, JK | 1 |
Auersperg, N; Cheng, JC; Leung, PC | 1 |
Ahmed, AA; Bast, RC; Bornmann, WG; Chen, MY; Hennessey, V; Liao, WS; Lu, Z; Rosner, GL; Washington, MN; Yu, Y | 1 |
Dong, R; Pu, H; Qiu, H; Yu, J; Zhu, J | 1 |
Bhattacharyya, B; Hallett, M; Han, ZG; Huang, J; Stefanska, B; Suderman, M; Szyf, M | 1 |
Alvarez Secord, A; Darcy, KM; Havrilesky, LJ; Huang, Z; Hutson, A; Jewell, EL; Lee, PS; Markman, M; Muggia, F; Murphy, SK | 1 |
Blanco-Fernández, A; Dempsey, E; Harvey, DJ; Madden, SF; Mariño, K; McCann, A; Peracaula, R; Pérez-Garay, M; Rudd, PM; Saldova, R; Struwe, WB; Watson, JA | 1 |
Brown, R; Dai, W; Plumb, JA; Rizzo, S; Siddiq, A; Steele, NL; van der Zee, A; Walley, AJ; Wilhelm-Benartzi, CS; Zeller, C | 1 |
Arnold, A; Berry, WA; Fang, F; Huang, T; Matei, D; Nephew, KP; Schilder, J; Shen, C; Zeng, Y | 1 |
Daudi, S; Kim, KM; Kim, MJ; Lee, SY; Miliotto, A; Odunsi, K; Old, L; Song, MH | 1 |
Calonne, E; Delbecque, K; Delvenne, P; Deplus, R; Ennaji, MM; Fuks, F; Guenin, S; Kridelka, F; Krusy, N; Lampe, X; Mouallif, M | 1 |
Godwin, AK; Guo, S; Liu, M | 1 |
Di, W; Gu, L; Zhang, S; Zhu, J | 1 |
Gao, X; Han, D; Huang, H; Li, F; Ma, N; Qiao, Y; Wang, D; Wang, L; Wang, X; Wu, G; Xiang, Y; Zhang, G; Zhang, Y; Zhao, R; Zhou, J | 1 |
Godwin, AK; Gupta, A; Liu, J; Lu, A; Vanderveer, L | 1 |
Bates, PA; Brown, I; Contreras-Moreira, B; Gabra, H; Li, L; Massie, CE; Miller, EP; Miller, J; Rabiasz, GJ; Scott, D; Sellar, GC; Smyth, JF; Stronach, EA; Watt, KP; Williams, AR | 1 |
Facchinetti, F; Mezzanzanica, D; Modena, P; Pilotti, S; Radice, MT; Sozzi, G; Testi, MA | 1 |
Burrows, JF; Chanduloy, S; Donaghy, P; Godwin, AK; Johnston, PG; McIlhatton, MA; Nagar, H; Price, J; Russell, SE; Yeates, K | 1 |
Becker, M; Ebert, MP; Göhring, UJ; Hoffmann, J; Moser, N; Pur, S; Schöndorf, T; Weisshaar, MP | 1 |
Assaly, M; Benz, A; Cerato, C; Desmond, JC; Greloz, V; Hermeking, H; Herrmann, F; Koeffler, HP; Lodygin, D; Mhawech, P; Schwaller, J | 1 |
Kohno, T; Nishioka, M; Ochiai, K; Okamoto, A; Otsuka, A; Tanaka, T; Yanaihara, N; Yokota, J | 1 |
Imura, M; Maekita, T; Miyamoto, K; Nakagawa, S; Takada, T; Taketani, Y; Tsao, SW; Ushijima, T; Yagi, Y; Yasugi, T; Yoshino, O | 1 |
Chan, KY; Cheung, AN; Chiu, PM; Ip, P; Khoo, US; Ngan, HY; Shen, DH; Xue, WC | 1 |
Haller, G; Horak, P; Horvat, R; Krainer, M; Pils, D; Pribill, I; Roessler, M; Tomek, S; Zeillinger, R; Zielinski, C | 1 |
Balch, C; Craft, T; Huang, TH; Nephew, KP; Skalnik, DG; Yan, P; Young, S | 1 |
Brown, R; Chan, MW; Huang, TH; Liu, JC; Liyanarachchi, S; Matei, DE; Nephew, KP; Wang, Z; Wei, SH; Wen, P; Yan, PS | 1 |
Cheng, X; Liu, J; Mei, FC; Young, TW | 1 |
Li, M; Lu, S; Wang, H; Wang, Z; Zhang, Y | 1 |
Ichimura, S; Mori, A; Nakazawa, K; Okochi-Takada, E; Ushijima, T; Wakabayashi, M; Yasugi, T | 1 |
Diamandis, EP; Pampalakis, G; Sotiropoulou, G | 1 |
Hongmei, L; Xiaoyan, X; Yuecheng, Y | 1 |
Dong, WH; He, XH; Huang, ZJ; Li, M; Li, XY; Wang, H; Wang, XY; Wang, ZH | 1 |
Calin, GA; Croce, CM; Di Leva, G; Godwin, AK; Iliopoulos, D; Negrini, M; Nicoloso, MS; Petrocca, F; Qin, HR; Shimizu, M; Trapasso, F; Vecchione, A; Wojcik, SE; Yendamuri, S | 1 |
Connolly, DC; Dinulescu, DM; Donahoe, PK; Halpern, EF; MacLaughlin, DT; Pearsall, LA; Pieretti-Vanmarcke, R; Seiden, MV | 1 |
Benigno, BB; Bowen, NJ; Dickerson, EB; Matyunina, LV; McDonald, JF; Menendez, L; Polavarapu, N; Walker, D | 1 |
Akahira, J; Ito, K; Moriya, T; Niikura, H; Okamura, K; Sakuma, M; Sasano, H; Yaegashi, N | 1 |
Aletti, G; Chien, J; Molina, J; Narita, K; Pan, Y; Qian, X; Roberts, LR; Scheerer, M; Shridhar, V; Staub, J | 1 |
D'Souza, T; Honda, H; Ji, H; Morin, PJ; Pazin, MJ | 1 |
Cortese, R; de Leij, LFMH; Jeltsch, A; Kiss, A; McLaughlin, PMJ; Monami, A; Raskó, T; Rots, MG; Ruiters, MHJ; Ślaska-Kiss, K; van der Gun, BTF; Wasserkort, R; Weinhold, E | 1 |
Izutsu, N; Maesawa, C; Masuda, T; Oikawa, H; Shibazaki, M; Shoji, T; Sugiyama, T | 1 |
Benigno, BB; Matyunina, LV; McDonald, JF; Menendez, L; Totten, KA; Walker, LD | 1 |
Blessing, JA; Look, KY; Manetta, A | 1 |
Parekh, HK; Simpkins, H | 1 |
Götzinger, N; Mueller-Lantzsch, N; Roemer, K; Sauter, M | 1 |
Brown, R; Illand, M; MacKean, MJ; Strathdee, G | 1 |
Brown, R; Kaye, SB; Plumb, JA; Sludden, J; Strathdee, G | 1 |
Avula, R; Bible, KC; Hartmann, LC; Huang, H; Kalli, K; Kaufmann, SH; Lee, YK; Shridhar, V; Smith, DI; Staub, J | 1 |
Arnold, JM; Chenevix-Trench, G; Cummings, M; Purdie, D | 1 |
Aird, RE; Chen, H; Cummings, J; Jodrell, DI; Morris, RE; Muir, M; Ritchie, AA; Sadler, PJ | 1 |
Kanoh, H; Makino, T; Matsui, Y; Okudaira, Y | 1 |
Cavalli, F; Renard, J; Sessa, C; Stoter, G; ten Bokkel Huinink, W | 1 |
9 trial(s) available for azacitidine and Cancer of Ovary
Article | Year |
---|---|
A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gemcitabine; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Patient Safety; Polyethylene Glycols; Survival Rate; Topotecan; Treatment Outcome | 2020 |
Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer.
Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cancer Vaccines; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Decitabine; DNA Methylation; Doxorubicin; Epigenesis, Genetic; Female; Gene Expression; Humans; Immunity, Humoral; Immunotherapy, Active; Long Interspersed Nucleotide Elements; Membrane Proteins; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polyethylene Glycols; T-Lymphocyte Subsets; Treatment Outcome | 2014 |
A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent, partially platinum-sensitive ovarian cancer.
Topics: Adaptor Proteins, Signal Transducing; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; MutL Protein Homolog 1; Neoplasm Recurrence, Local; Nuclear Proteins; Ovarian Neoplasms; Platinum | 2014 |
Low Dose Decitabine Combined with Taxol and Platinum Chemotherapy to Treat Refractory/Recurrent Ovarian Cancer: An Open-Label, Single-Arm, Phase I/II Study.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Decitabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Ovarian Neoplasms; Paclitaxel; Platinum; Recurrence; Safety | 2015 |
Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Carboplatin; Decitabine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Ovarian Neoplasms; Pilot Projects; Prognosis; Survival Rate; Young Adult | 2015 |
A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Decitabine; DNA Methylation; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Platinum Compounds | 2010 |
Phase 1b-2a study to reverse platinum resistance through use of a hypomethylating agent, azacitidine, in patients with platinum-resistant or platinum-refractory epithelial ovarian cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Carcinoma, Ovarian Epithelial; Disease-Free Survival; DNA Methylation; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms | 2011 |
Epigenetic resensitization to platinum in ovarian cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Decitabine; Disease-Free Survival; DNA Methylation; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Peritoneal Neoplasms | 2012 |
A phase II study of fazarabine in patients with advanced ovarian cancer. A Gynecologic Oncology Group study.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Female; Humans; Infusions, Intravenous; Neoplasm Recurrence, Local; Ovarian Neoplasms; Treatment Outcome | 1995 |
104 other study(ies) available for azacitidine and Cancer of Ovary
Article | Year |
---|---|
Sequential azacitidine and carboplatin induces immune activation in platinum-resistant high-grade serous ovarian cancer cell lines and primes for checkpoint inhibitor immunotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Cell Growth Processes; Cell Line, Tumor; DNA Methylation; Female; Humans; Immune Checkpoint Inhibitors; Immunity; Neoplasm Grading; Neoplasms, Cystic, Mucinous, and Serous; Ovarian Neoplasms; Signal Transduction; Up-Regulation | 2022 |
Investigation of role of CpG methylation in some epithelial mesenchymal transition gene in a chemoresistant ovarian cancer cell line.
Topics: Azacitidine; Cell Line, Tumor; Cisplatin; CpG Islands; DNA Methylation; Drug Resistance, Neoplasm; Epithelial Cell Adhesion Molecule; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms | 2022 |
Global miRNA/proteomic analyses identify miRNAs at 14q32 and 3p21, which contribute to features of chronic iron-exposed fallopian tube epithelial cells.
Topics: Azacitidine; Biomarkers, Tumor; Cell Line, Transformed; Cell Transformation, Neoplastic; Down-Regulation; Epithelial Cells; Fallopian Tubes; Female; Ferric Compounds; Gene Expression Profiling; Genetic Loci; Humans; MDS1 and EVI1 Complex Locus Protein; MicroRNAs; Ovarian Neoplasms; Proteome; Proteomics; Quaternary Ammonium Compounds; Transcriptome; Transfection; Vorinostat | 2021 |
Targeting Ovarian Cancer Stem Cells by Dual Inhibition of HOTAIR and DNA Methylation.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Humans; Mice; Neoplastic Stem Cells; Ovarian Neoplasms; Peptide Nucleic Acids; RNA, Long Noncoding; Xenograft Model Antitumor Assays | 2021 |
Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Cell Proliferation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Ovarian Neoplasms; Repetitive Sequences, Nucleic Acid; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2021 |
Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Benzamides; Cell Line, Tumor; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Drug Synergism; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens Class II; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Mice; Ovarian Neoplasms; Panobinostat; Pyridines; RNA, Messenger; Transcription, Genetic; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden.
Topics: Animals; Antineoplastic Agents, Immunological; Azacitidine; Cell Line, Tumor; Disease Models, Animal; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Immunomodulation; Interferon Type I; Mice; Ovarian Neoplasms; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Dual Inhibition of DNA and Histone Methyltransferases Increases Viral Mimicry in Ovarian Cancer Cells.
Topics: Antineoplastic Agents; Azacitidine; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Methylation; Drug Synergism; Endogenous Retroviruses; Female; Histone-Lysine N-Methyltransferase; Histones; Humans; Ovarian Neoplasms; Prognosis; Sequence Analysis, RNA; Transcriptional Activation | 2018 |
IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Azacitidine; Cell Line, Tumor; Cytokines; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Drug Therapy; Epigenomics; Female; Humans; Immunotherapy; Interleukin-6; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neoplastic Stem Cells; Ovarian Neoplasms; Platinum; Retinal Dehydrogenase; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment; Up-Regulation | 2018 |
DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cystadenocarcinoma, Serous; Disease Models, Animal; Eflornithine; Female; Immunity, Innate; Macrophages; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; Polyamines; Tumor Cells, Cultured; Tumor Microenvironment | 2019 |
STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer.
Topics: Acetylation; Adult; Azacitidine; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; rho GTP-Binding Proteins; STAT3 Transcription Factor | 2013 |
Inhibition of DNA methyltransferases, histone deacetylases and lysine-specific demethylase-1 suppresses the tumorigenicity of the ovarian cancer ascites cell line SKOV3.
Topics: Acetylation; Animals; Ascites; Azacitidine; Cadherins; Carcinogenesis; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Histones; Humans; Hydroxamic Acids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C3H; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Nuclear Proteins; Ovarian Neoplasms; Spheroids, Cellular; Tumor Cells, Cultured; Twist-Related Protein 1 | 2013 |
The different faces of myelodysplasia in peripheral blood granulocytes.
Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Chemotherapy, Adjuvant; Decitabine; Female; Granulocytes; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary; Ovarian Neoplasms; Remission Induction | 2014 |
Transcription factor WT1 and promoter CpG hypomethylation coactivate HOXA10 expression in ovarian cancer.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; CpG Islands; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Homeobox A10 Proteins; Homeodomain Proteins; Humans; Middle Aged; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Small Interfering; Transfection; Up-Regulation; WT1 Proteins | 2014 |
Association of promoter methylation of VGF and PGP9.5 with ovarian cancer progression.
Topics: Adult; Aged; Azacitidine; Base Sequence; Cohort Studies; Decitabine; Disease Progression; DNA Methylation; DNA Primers; Female; Humans; Middle Aged; Nerve Growth Factors; Ovarian Neoplasms; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Ubiquitin Thiolesterase | 2013 |
Expression loss and revivification of RhoB gene in ovary carcinoma carcinogenesis and development.
Topics: Antineoplastic Agents; Azacitidine; Carcinogenesis; Case-Control Studies; Cystadenoma, Serous; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Hydroxamic Acids; Methyltransferases; Neoplasm Staging; Ovarian Neoplasms; Ovary; rhoB GTP-Binding Protein | 2013 |
Methylation of OPCML promoter in ovarian cancer tissues predicts poor patient survival.
Topics: Adult; Age Factors; Aged; Azacitidine; Biomarkers; Cell Adhesion Molecules; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; GPI-Linked Proteins; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; RNA; Sequence Analysis, DNA | 2014 |
Epigenetic silencing of the LDOC1 tumor suppressor gene in ovarian cancer cells.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Cell Line; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Middle Aged; Ovarian Neoplasms; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction | 2014 |
Aberrant methylation of RASSF2A in tumors and plasma of patients with epithelial ovarian cancer.
Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Tumor Suppressor Proteins | 2014 |
Epigenetic modification boosts ovarian cancer vaccination.
Topics: Antigens, Neoplasm; Azacitidine; Cancer Vaccines; Carcinoma, Ovarian Epithelial; Combined Modality Therapy; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Treatment Outcome | 2014 |
Aberrant DNA methylation in the IFITM1 promoter enhances the metastatic phenotype in an intraperitoneal xenograft model of human ovarian cancer.
Topics: Animals; Antigens, Differentiation; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Xenograft Model Antitumor Assays | 2014 |
Promoter hypermethylation influences the suppressive role of maternally expressed 3, a long non-coding RNA, in the development of epithelial ovarian cancer.
Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; RNA, Long Noncoding; Tumor Suppressor Protein p53 | 2014 |
Aberrant hypomethylation-mediated AGR2 overexpression induces an aggressive phenotype in ovarian cancer cells.
Topics: Animals; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mucoproteins; Neoplasm Metastasis; Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Oncogene Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Proteins | 2014 |
Clinical importance and therapeutic implication of E-cadherin gene methylation in human ovarian cancer.
Topics: Adult; Aged; Azacitidine; Cadherins; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Molecular Targeted Therapy; Ovarian Neoplasms; Promoter Regions, Genetic; Young Adult | 2014 |
Decitabine reactivated pathways in platinum resistant ovarian cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression; Gene Expression Profiling; Humans; Ovarian Neoplasms | 2014 |
Epigenetic targeting of ovarian cancer stem cells.
Topics: Aldehyde Dehydrogenase; Animals; Azacitidine; Carboplatin; Cell Differentiation; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Ovarian Neoplasms | 2014 |
Expression of GBGT1 is epigenetically regulated by DNA methylation in ovarian cancer cells.
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; N-Acetylgalactosaminyltransferases; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic | 2014 |
FT-IR microspectrometry reveals the variation of membrane polarizability due to epigenomic effect on epithelial ovarian cancer.
Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Membrane; Chromatography, High Pressure Liquid; CpG Islands; Decitabine; Deoxycytidine Monophosphate; DNA Methylation; DNA, Ribosomal; Epigenomics; Female; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Spectroscopy, Fourier Transform Infrared | 2014 |
The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cisplatin; Disease Models, Animal; DNA Adducts; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Ovarian Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
DNA hypomethylation-mediated overexpression of carbonic anhydrase 9 induces an aggressive phenotype in ovarian cancer cells.
Topics: Animals; Azacitidine; Carbonic Anhydrases; Carcinoma, Ovarian Epithelial; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Phenotype; Promoter Regions, Genetic; RNA, Messenger | 2014 |
TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells.
Topics: Antigens, CD; Azacitidine; Cadherins; Cell Line, Tumor; Collagen Type I; Collagen Type I, alpha 1 Chain; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Enzyme Inhibitors; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; Transforming Growth Factor beta | 2014 |
Frequent Loss of NISCH Promotes Tumor Proliferation and Invasion in Ovarian Cancer via Inhibiting the FAK Signal Pathway.
Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Female; Focal Adhesion Kinase 1; Humans; Imidazoline Receptors; Intracellular Signaling Peptides and Proteins; Loss of Heterozygosity; Neoplasm Invasiveness; Neoplasm Transplantation; Ovarian Neoplasms; Promoter Regions, Genetic; Signal Transduction | 2015 |
Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts.
Topics: Animals; Antigens, Neoplasm; Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; DNA Methylation; Enzyme Inhibitors; Heterografts; Humans; Methyltransferases; Mice, SCID; Neoplasm Transplantation; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; T-Lymphocytes | 2015 |
KRAS Genomic Status Predicts the Sensitivity of Ovarian Cancer Cells to Decitabine.
Topics: Animals; Azacitidine; Biomarkers, Tumor; Cystadenocarcinoma, Serous; Decitabine; Drug Resistance, Neoplasm; Female; Genes, ras; Humans; Mice; Mice, Nude; Mice, Transgenic; Mutation; Ovarian Neoplasms; Prognosis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2015 |
Decitabine Enhances Lymphocyte Migration and Function and Synergizes with CTLA-4 Blockade in a Murine Ovarian Cancer Model.
Topics: Animals; Antineoplastic Agents; Ascitic Fluid; Azacitidine; CD8-Positive T-Lymphocytes; Cell Movement; Cell Transformation, Neoplastic; CTLA-4 Antigen; Cytokines; Decitabine; Female; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Killer Cells, Natural; Lymph Nodes; Lymphocytes, Tumor-Infiltrating; Mice; Ovarian Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2015 |
DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer.
Topics: Aged; Antigens, Neoplasm; Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger | 2015 |
Evaluation of Epigenetic Drug Targeting of Heterogenous Tumor Cell Fractions Using Potential Biomarkers of Response in Ovarian Cancer.
Topics: Animals; Azacitidine; Benzamidines; Biomarkers, Tumor; Curcumin; Cytochrome P-450 Enzyme System; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Hydroxamic Acids; Molecular Targeted Therapy; Ovarian Neoplasms; Piperazines; Proteins; Retinoid X Receptor gamma | 2015 |
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
Topics: Animals; Azacitidine; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; Endogenous Retroviruses; Female; Humans; Immunotherapy; Interferon Type I; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; RNA, Double-Stranded | 2015 |
[Reversal effect of 5-aza-2-deoxycytidine on the maternally expressed gene 3 promoter hypermethylation and its inhibitory effect on the proliferation of epithelial ovarian cancer cells].
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Ovarian Epithelial; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Female; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger | 2015 |
NDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms.
Topics: Animals; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Movement; CpG Islands; Decitabine; DNA Methylation; Epithelium; Female; Focal Adhesion Kinase 1; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Loss of Heterozygosity; Mice; Mice, Nude; Nerve Tissue Proteins; Nuclear Proteins; Ovarian Neoplasms; Ovary; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins pp60(c-src); rhoA GTP-Binding Protein; Stress Fibers; Tumor Suppressor Proteins | 2016 |
Prediction of key genes in ovarian cancer treated with decitabine based on network strategy.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Cell Cycle Proteins; Computational Biology; Cyclin B1; Databases, Genetic; Decitabine; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Interleukin-1beta; Interleukin-2; Microarray Analysis; Nuclear Proteins; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Reverse Transcriptase Polymerase Chain Reaction | 2016 |
Upregulation of p27Kip1 by demethylation sensitizes cisplatin-resistant human ovarian cancer SKOV3 cells.
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Cisplatin; Cyclin-Dependent Kinase Inhibitor p27; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms | 2016 |
Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Ovarian Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Flow Cytometry; Gene Expression; Histocompatibility Antigens Class I; Humans; Ovarian Neoplasms; Polymerase Chain Reaction; Up-Regulation | 2009 |
Expression and promoter methylation status of mismatch repair gene hMLH1 and hMSH2 in epithelial ovarian cancer.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Base Pair Mismatch; Case-Control Studies; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; MutL Protein Homolog 1; MutL Proteins; Neoplasm Proteins; Neoplasm Staging; Nuclear Proteins; Ovarian Neoplasms; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP].
Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; MutL Protein Homolog 1; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger | 2008 |
Azacitidine enhances sensitivity of platinum-resistant ovarian cancer cells to carboplatin through induction of apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Carboplatin; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms | 2009 |
Aberrant promoter methylation of SPARC in ovarian cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Osteonectin; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Analysis; Tumor Cells, Cultured | 2009 |
Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo.
Topics: Acetylation; Adaptor Proteins, Signal Transducing; Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Hydroxamic Acids; Melanoma-Specific Antigens; Mice; Mice, Nude; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells.
Topics: Azacitidine; Cell Growth Processes; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor beta; Female; Histone Acetyltransferases; Humans; Hydroxamic Acids; Ovarian Neoplasms; Promoter Regions, Genetic | 2009 |
Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Cell Line, Tumor; Cell Proliferation; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Epithelial Cells; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Membrane Transport Proteins; Molecular Sequence Data; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Promoter Regions, Genetic; Proteolipids; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Survivors | 2010 |
RUNX3 gene methylation in epithelial ovarian cancer tissues and ovarian cancer cell lines.
Topics: Azacitidine; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger | 2009 |
[E-cadherin promoter methylation and demethylation in epithelial ovarian carcinoma cells].
Topics: Azacitidine; Cadherins; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; CpG Islands; DNA Methylation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic | 2009 |
Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Muscle Proteins; Ovarian Neoplasms; Prognosis; Promoter Regions, Genetic; Proportional Hazards Models; SKP Cullin F-Box Protein Ligases; Smad4 Protein; Taiwan; Transforming Growth Factor beta; Young Adult | 2010 |
BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines.
Topics: Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Organ Specificity; Ovarian Neoplasms; Promoter Regions, Genetic; Transcription Initiation Site | 2010 |
Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.
Topics: Azacitidine; Cadherins; Carcinoma; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Neoplasm Invasiveness; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Tumor Suppressor Protein p53 | 2011 |
Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Azacitidine; Cell Division; Cell Line, Tumor; Cell Proliferation; Decitabine; Drug Synergism; Drug Therapy, Combination; Epigenomics; Female; G2 Phase; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genomic Imprinting; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Transplantation, Heterologous; Vorinostat | 2011 |
SLIT2 is epigenetically silenced in ovarian cancers and suppresses growth when activated.
Topics: Apoptosis; Azacitidine; Case-Control Studies; Cell Proliferation; DNA; DNA Methylation; Epigenomics; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Intercellular Signaling Peptides and Proteins; Nerve Tissue Proteins; Ovarian Neoplasms; Ovary; Polymerase Chain Reaction; Promoter Regions, Genetic; Tumor Cells, Cultured; Wound Healing | 2011 |
Definition of the landscape of promoter DNA hypomethylation in liver cancer.
Topics: Aged; Azacitidine; Breast Neoplasms; Carcinoma, Hepatocellular; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Ovarian Neoplasms; Promoter Regions, Genetic | 2011 |
The regulation of MASPIN expression in epithelial ovarian cancer: association with p53 status, and MASPIN promoter methylation: a gynecologic oncology group study.
Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Promoter Regions, Genetic; Serpins; Tumor Suppressor Protein p53 | 2011 |
5-AZA-2'-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer.
Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Decitabine; Female; Glycoproteins; Glycosylation; Glycosyltransferases; Humans; Methylation; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Polysaccharides | 2011 |
Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cisplatin; Collagen Type I; Collagen Type I, alpha 1 Chain; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Epigenomics; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Midkine; MutL Protein Homolog 1; Nerve Growth Factors; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides | 2012 |
A novel cancer/testis antigen KP-OVA-52 identified by SEREX in human ovarian cancer is regulated by DNA methylation.
Topics: Antibodies, Neoplasm; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Library; Humans; Male; Ovarian Neoplasms; Recombinant Fusion Proteins; RNA, Messenger; Testicular Neoplasms | 2012 |
Aberrant promoter methylation and expression of UTF1 during cervical carcinogenesis.
Topics: Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cervix Uteri; Cluster Analysis; Cytological Techniques; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Neoplasms, Glandular and Epithelial; Neoplastic Stem Cells; Nuclear Proteins; Octamer Transcription Factor-3; Ovarian Neoplasms; Promoter Regions, Genetic; Sequence Analysis, DNA; SOXB1 Transcription Factors; Trans-Activators; Uterine Cervical Neoplasms | 2012 |
Transcriptional regulation of hTREX84 in human cancer cells.
Topics: Azacitidine; Base Sequence; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Decitabine; DNA-Binding Proteins; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; RNA-Binding Proteins; Sequence Analysis, DNA; Sulfites; Transcription Factor RelA; Transcription, Genetic | 2012 |
Epigenetic silencing of DKK2 and Wnt signal pathway components in human ovarian carcinoma.
Topics: Animals; Azacitidine; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Mice; Neoplasm Invasiveness; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Wnt Signaling Pathway | 2012 |
MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Hep G2 Cells; Humans; Mice; Mice, Nude; MicroRNAs; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Xenograft Model Antitumor Assays | 2014 |
Anticancer efficacy of cisplatin and trichostatin A or 5-aza-2'-deoxycytidine on ovarian cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Cisplatin; Decitabine; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Inbred C3H; Mice, SCID; Ovarian Neoplasms; Spheroids, Cellular; Tumor Cells, Cultured | 2013 |
Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma.
Topics: Azacitidine; Breast Neoplasms; CpG Islands; Decitabine; DNA Methylation; Epithelial Cells; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Nerve Tissue Proteins; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synucleins; Tumor Cells, Cultured | 2003 |
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.
Topics: Animals; Azacitidine; Breast Neoplasms; Carrier Proteins; Case-Control Studies; Cell Adhesion Molecules; Chromosomes, Human, Pair 11; CpG Islands; DNA; DNA Methylation; Enzyme Inhibitors; Female; Genes, Tumor Suppressor; GPI-Linked Proteins; Humans; Loss of Heterozygosity; Mice; Mice, Nude; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neoplasms, Glandular and Epithelial; Nerve Tissue Proteins; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tumor Cells, Cultured | 2003 |
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 22; CpG Islands; DNA Methylation; DNA-Binding Proteins; Electron Transport Complex III; Exons; Extrachromosomal Inheritance; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Kruppel-Like Transcription Factors; Molecular Sequence Data; Neoplasm Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Proteins; Repressor Proteins; RNA-Binding Protein EWS; Sarcoma; Soft Tissue Neoplasms; Translocation, Genetic; Tumor Cells, Cultured | 2003 |
Altered expression of the septin gene, SEPT9, in ovarian neoplasia.
Topics: Adult; Azacitidine; Base Sequence; Cell Line, Tumor; DNA, Circular; Female; Fetus; Gene Expression Regulation, Neoplastic; GTP Phosphohydrolases; Humans; Methylation; Mutation; Ovarian Neoplasms; Protein Splicing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Septins; Transcription, Genetic | 2003 |
Hypermethylation of the PTEN gene in ovarian cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Phosphoric Monoester Hydrolases; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2004 |
Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation.
Topics: 14-3-3 Proteins; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; CpG Islands; DNA Methylation; Down-Regulation; Endometrial Neoplasms; Exonucleases; Exoribonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mutation; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; RNA, Messenger; Tissue Array Analysis; Tumor Suppressor Protein p53 | 2005 |
Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer.
Topics: Azacitidine; Carcinoma, Endometrioid; Case-Control Studies; Chromosomes, Human, Pair 22; Cystadenocarcinoma, Mucinous; Cystadenocarcinoma, Serous; Decitabine; DNA Methylation; DNA Mutational Analysis; Female; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Mutation, Missense; Myosin Heavy Chains; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Tumor Cells, Cultured | 2004 |
Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.
Topics: Adult; Aged; Azacitidine; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Middle Aged; Ovarian Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wnt Proteins | 2004 |
Epigenetic and genetic alterations of p33ING1b in ovarian cancer.
Topics: Adenocarcinoma, Clear Cell; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Endometrioid; Case-Control Studies; Cell Cycle Proteins; CpG Islands; Cystadenocarcinoma, Mucinous; Cystadenocarcinoma, Serous; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Immunoenzyme Techniques; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Loss of Heterozygosity; Mutation; Nuclear Proteins; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2005 |
Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Cell Line, Tumor; Decitabine; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunohistochemistry; Membrane Glycoproteins; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2005 |
Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Cytidine; Decitabine; DNA Methylation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Ovarian Neoplasms | 2005 |
Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Decitabine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA, Ribosomal; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Multivariate Analysis; Ovarian Neoplasms; Prognosis; RNA, Ribosomal, 18S; RNA, Ribosomal, 28S; Survival Analysis | 2005 |
RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells.
Topics: Azacitidine; Cell Adhesion Molecules; Cell Line, Transformed; Cell Transformation, Neoplastic; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Epithelial Cells; Female; Gene Silencing; Genes, ras; GPI-Linked Proteins; Humans; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; Signal Transduction | 2006 |
Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting Fanconi anemia-BRCA pathway.
Topics: Animals; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Fanconi Anemia; Fanconi Anemia Complementation Group F Protein; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Ovary; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2006 |
Silencing of the UCHL1 gene in human colorectal and ovarian cancers.
Topics: Azacitidine; Colorectal Neoplasms; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; Tumor Cells, Cultured; Ubiquitin Thiolesterase | 2006 |
The epigenetic basis for the aberrant expression of kallikreins in human cancers.
Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Male; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms | 2006 |
Clinical evaluation of E-cadherin expression and its regulation mechanism in epithelial ovarian cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cadherins; Cell Line, Tumor; DNA Primers; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
[Disfigurement of p16INK4A gene expression in development of ovarian cancer and the mechanism].
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Seeding; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2006 |
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.
Topics: ADP-Ribosylation Factors; Apoptosis; Azacitidine; Breast Neoplasms; Cell Proliferation; Decitabine; Down-Regulation; Female; Genes, Tumor Suppressor; Humans; Ovarian Neoplasms | 2006 |
Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer.
Topics: Animals; Anti-Mullerian Hormone; Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; Drug Resistance, Neoplasm; Female; Glycoproteins; Humans; Immunoglobulin G; Melphalan; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Receptors, Peptide; Receptors, Transforming Growth Factor beta; Testicular Hormones; Xenograft Model Antitumor Assays | 2006 |
Identification of candidate methylation-responsive genes in ovarian cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Ovarian Neoplasms | 2007 |
Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cyclin D2; Cyclins; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Immunohistochemistry; Ovarian Neoplasms; Prognosis; Promoter Regions, Genetic; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Chromatin; Cisplatin; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Middle Aged; Ovarian Neoplasms; Sulfotransferases | 2007 |
Regulation of the CLDN3 gene in ovarian cancer cells.
Topics: Azacitidine; Binding Sites; Cell Line, Tumor; Claudin-3; Claudin-4; CpG Islands; Decitabine; DNA Methylation; Female; Humans; Hydroxamic Acids; Membrane Proteins; Mutagenesis, Site-Directed; Ovarian Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Sp3 Transcription Factor | 2007 |
Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Azacitidine; Carcinoma; Cell Adhesion Molecules; Cell Line, Tumor; Cell Nucleus; DNA Methylation; DNA-Cytosine Methylases; Down-Regulation; Epithelial Cell Adhesion Molecule; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Time Factors; Transcription, Genetic; Up-Regulation | 2008 |
Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells.
Topics: Azacitidine; CpG Islands; Cystadenocarcinoma, Serous; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Ovarian Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Tubulin; Tumor Cells, Cultured | 2008 |
Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors.
Topics: Adult; Aged; Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; DNA Methylation; Epigenesis, Genetic; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens Class I; HLA Antigens; HLA-G Antigens; Humans; Middle Aged; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transcription Initiation Site | 2008 |
The differential expression of cytokeratin 18 in cisplatin-sensitive and -resistant human ovarian adenocarcinoma cells and its association with drug sensitivity.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Cisplatin; DNA Damage; Drug Resistance; Female; Humans; Keratins; Ovarian Neoplasms; Tumor Cells, Cultured | 1995 |
Regulation of human endogenous retrovirus-K Gag expression in teratocarcinoma cell lines and human tumours.
Topics: Azacitidine; Butyrates; Butyric Acid; DNA Methylation; DNA, Viral; Female; Gene Products, gag; Humans; Male; Methylation; Ovarian Neoplasms; Retroelements; Teratocarcinoma; Testicular Neoplasms; Tumor Cells, Cultured | 1996 |
A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Azacitidine; Base Pair Mismatch; Carrier Proteins; Cisplatin; Cross-Linking Reagents; DNA Methylation; DNA Repair; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic | 1999 |
Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Base Pair Mismatch; Carboplatin; Carrier Proteins; Cisplatin; Colonic Neoplasms; Dacarbazine; Decitabine; DNA Methylation; DNA Repair; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2000 |
Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer.
Topics: Amino Acid Sequence; Azacitidine; Base Sequence; Chromosome Mapping; Cisplatin; Cloning, Molecular; Decitabine; DNA, Neoplasm; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Humans; In Situ Hybridization, Fluorescence; Loss of Heterozygosity; Molecular Sequence Data; Ovarian Neoplasms; Oximes; Paclitaxel; Piperazines; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Topotecan; Transfection; Tumor Cells, Cultured | 2001 |
Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; DNA Primers; DNA, Neoplasm; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Adhesion Molecule-1; Loss of Heterozygosity; Methylation; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Prognosis; RNA, Messenger; Survival Analysis; Tumor Cells, Cultured | 2001 |
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Calcium Channel Blockers; Carboplatin; Cisplatin; Decitabine; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Edetic Acid; Female; Humans; Ligands; Mice; Mice, Nude; Neoplasm Proteins; Organometallic Compounds; Ovarian Neoplasms; Ruthenium Compounds; Structure-Activity Relationship; Verapamil; Xenograft Model Antitumor Assays | 2002 |
[Primary culture and characterization of human ovarian surface epithelial cells].
Topics: Adult; Azacitidine; Collagen; Culture Media; Epithelium; Female; Gels; Humans; Middle Aged; Ovarian Neoplasms; Ovary; Tumor Cells, Cultured | 1990 |
Phase II study of 5-aza-2'-deoxycytidine in advanced ovarian carcinoma. The EORTC Early Clinical Trials Group.
Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Carcinoma; Decitabine; Drug Evaluation; Female; Humans; Middle Aged; Ovarian Neoplasms | 1990 |