azacitidine has been researched along with Cancer of Nasopharynx in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.33) | 18.7374 |
| 1990's | 1 (2.33) | 18.2507 |
| 2000's | 17 (39.53) | 29.6817 |
| 2010's | 23 (53.49) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, W; Liu, H; Zhang, W; Zhang, Y | 1 |
| Bossi, P; Chen, P; Haddad, RI; Hansen, AR; Hsieh, CY; Licitra, LF; Mesia, R; Miller, J; Siu, LL; Tan, EH | 1 |
| Liu, J; Liu, W; Luo, B; Wang, J; Zhao, Z | 1 |
| Li, H; Lin, C; Ran, Y; Wang, Z; Yang, W; You, Y; Zhu, H | 1 |
| Du, C; Hou, B; Huang, G; Huang, T; Mo, Y; Tian, F; Wang, S; Xiao, X; You, J; Yu, N; Zeng, X; Zhang, J; Zhang, Z; Zhao, W; Zhou, S; Zhou, X | 1 |
| Gong, P; Li, J; Li, X; Lyu, X; Peng, H; Yao, K | 1 |
| Allaya, N; Ayadi, W; Daoud, J; Frikha, H; Frikha, M; Gargouri, A; Ghorbel, A; Khabir, A; Mokdad-Gargouri, R; Trigui, E | 1 |
| Claret, FX; Wang, S; Yang, H; Zhang, R | 1 |
| Liu, ZH; Luo, FY; Tang, CE; Xiao, S; Xiao, ZQ; Zhang, PF | 1 |
| Almgren, M; Du, ZM; Ernberg, I; Hu, LF; Ignatyev, I; Kashuba, V; Moumad, K; Nawaz, I; Pavlova, TV; Zabarovsky, ER | 1 |
| Chen, F; Du, C; Ernberg, I; He, Q; Huang, G; Huang, T; Lan, Y; Lin, L; Matskova, L; Mo, Y; Murata, M; Wang, S; Wei, J; Wei, L; Xiao, X; Xie, Y; Zhang, Z; Zhou, X | 1 |
| Chan, JY; Ho, WK; Man, OY; To, VS; Tsang, CM; Tsang, RK; Tsao, SW; Wei, WI; Wong, TS | 1 |
| Chan, AW; Chan, MW; Chau, SL; Lee, TL; Leung, PP; Lo, KW; Lung, RW; Ng, DC; So, KK; To, KF; Tong, JH | 1 |
| Chen, JY; Hong, CQ; Ran, YG; Wu, X; You, YJ | 1 |
| Ran, Y; Wu, S; You, Y | 1 |
| Du, C; Huang, G; Huang, T; Lin, L; Ma, N; Mo, Y; Murata, M; Wang, S; Xiao, X; Yu, N; Zhang, J; Zhang, Z; Zhou, X | 1 |
| Li, YC; Yi, HM; Zhong, RH | 1 |
| Alajez, NM; Bruce, J; Huang, SH; Hui, AB; Ito, E; Lenarduzzi, M; Liu, FF; O'Sullivan, B; Shi, W; Waldron, J; Xu, W; Yue, S | 1 |
| Li, G; Li, W; Li, X; Liao, Q; Ma, J; McCarthy, JB; Su, B; Tan, Y; Wang, W; Wu, M; Xiang, B; Xiong, W; Yang, J; Yi, M; Zhang, Z | 1 |
| He, D; Hong, S; Hu, G; Hu, Q; Qian, Y; Ren, G; Xiang, T; Zeng, Q; Zhu, J | 1 |
| Chan, SH; Chen, H; Cheung, FM; Chiu, PM; Chua, D; Hyytiainen, M; Kan, R; Keski-Oja, J; Ko, JM; Kwong, DL; Lee, AW; Lung, ML; Nicholls, JM; Stanbridge, EJ; Tao, Q; Tsao, SW; Wong, VC; Zabarovsky, ER | 1 |
| He, G; Li, H; Li, W; Ma, Y; Tan, G; Zhang, X | 1 |
| Li, G; Li, W; Li, X; Wang, W; Xiang, B; Yi, M | 1 |
| Cai, Z; Jin, Q; Li, Z; Liu, C; Tao, B; Yan, C | 1 |
| Chan, A; Chang, HW; Kwong, DL; Sham, JS; Wei, WI; Yuen, AP | 1 |
| Chen, HK; Feng, QS; Li, A; Liu, XQ; Long, QX; Pan, ZG; Wang, XZ; Zeng, YX; Zhang, XS | 1 |
| Chan, AS; Chan, SY; Chow, LS; Huang, DP; Hui, AB; Kwong, J; Lam, EC; Lo, KW; Teo, PM | 1 |
| Ambinder, RF; Chan, AT; Flinn, IW; Johnson, PJ; Klencke, B; Kwan, WH; Leung, TW; Mann, RB; Robertson, KD; Tao, Q | 1 |
| Chow, LS; Dammann, R; Huang, DP; Kwong, J; Lam, CW; Lo, KW; To, KF; Tsang, KS | 1 |
| Lim, CY; Loh, KS; Qiu, GH; Srivastava, G; Tan, LK; Tao, Q; Tsai, ST; Tsao, SW | 1 |
| Chow, LS; Huang, DP; Kwong, J; Lo, KW; Wong, AY | 1 |
| Chan, FL; Chow, LS; Huang, DP; Kwong, J; Lo, KW; To, KF | 1 |
| Chan, FL; Chow, LS; Choy, KW; Huang, DP; Kwong, J; Lo, KW; Mok, SC; To, KF | 1 |
| Han, YC; Kong, WJ; Wang, YJ; Zhang, D; Zhang, S | 1 |
| Chan, AT; Langford, C; Li, H; Murray, P; Putti, T; Seng, TJ; Srivastava, G; Tao, Q; Tsao, SW; Ying, J | 1 |
| Chen, JK; Chou, J; He, B; Jablons, DM; Kim, J; Kuchenbecker, K; Lin, YC; Mikami, I; Raz, D; Thung, E; Xu, Z; Yang, CT; You, L | 1 |
| Chen, X; Guo, CK; Kong, W; Kong, WJ; Liu, Z; Wang, YJ; Zhang, D; Zhang, S; Zhang, SL | 1 |
| Hu, L; Huang, G; Sun, D; Tang, A; Van, do N; Zhang, Z | 1 |
| Wang, H; Xia, B; Yi, ZC; Zhang, GY | 1 |
| Chan, AT; Chan, SL; Cui, Y; Jin, H; Lee, KY; Li, H; Ng, KM; Rha, SY; Robertson, KD; Srivastava, G; Tao, Q; Tsao, GS; van Hasselt, A; Wang, Y; Zhong, S | 1 |
| Li, H; Peng, D; Ren, CP; Wang, L; Yao, KT; Yi, HM; Zhang, HJ; Zhao, M | 1 |
| Altiok, E; Contreras-Brodin, B; Ernberg, I; Hu, LF; Klein, G; Minarovits, J | 1 |
| Busson, P; Ernberg, I; Falk, K; Klein, G; Masucci, MG; Minarovits, J; Tursz, T | 1 |
1 trial(s) available for azacitidine and Cancer of Nasopharynx
| Article | Year |
|---|---|
Phase II study of CC-486 (oral azacitidine) in previously treated patients with locally advanced or metastatic nasopharyngeal carcinoma.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Asian People; Azacitidine; Chemotherapy-Induced Febrile Neutropenia; Disease-Free Survival; Female; Humans; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Native Hawaiian or Other Pacific Islander; Neoplasm Recurrence, Local; Neutropenia; Progression-Free Survival; White People | 2019 |
42 other study(ies) available for azacitidine and Cancer of Nasopharynx
| Article | Year |
|---|---|
TMEM130 regulates cell migration through DNA methylation in nasopharyngeal carcinoma.
Topics: Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; RNA, Messenger | 2022 |
The effect of EBV on WIF1, NLK, and APC gene methylation and expression in gastric carcinoma and nasopharyngeal cancer.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Genes, APC; Herpesvirus 4, Human; Humans; Intracellular Signaling Peptides and Proteins; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Repressor Proteins; Stomach Neoplasms | 2017 |
Promoter hypermethylation contributes to the frequent suppression of the CDK10 gene in human nasopharyngeal carcinomas.
Topics: Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; CpG Islands; Cyclin-Dependent Kinases; Decitabine; DNA Methylation; Down-Regulation; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2013 |
Cytochrome b5 reductase 2 is a novel candidate tumor suppressor gene frequently inactivated by promoter hypermethylation in human nasopharyngeal carcinoma.
Topics: Adult; Aged; Animals; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cytochrome-B(5) Reductase; Decitabine; DNA Methylation; Female; Genes, Tumor Suppressor; Humans; Male; Mice; Mice, Inbred BALB C; Middle Aged; Nasopharyngeal Neoplasms; Promoter Regions, Genetic | 2014 |
Aberrant CpG island methylation of PTEN is an early event in nasopharyngeal carcinoma and a potential diagnostic biomarker.
Topics: Azacitidine; Base Sequence; Biomarkers, Tumor; Carcinoma; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Mutation; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; PTEN Phosphohydrolase; RNA, Messenger; Sequence Analysis, DNA | 2014 |
Identification of a novel methylated gene in nasopharyngeal carcinoma: TTC40.
Topics: Animals; Azacitidine; Carcinoma; Cell Line, Tumor; CpG Islands; Cytoskeletal Proteins; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Humans; Mice; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Proteins; Promoter Regions, Genetic; Proteins; Xenograft Model Antitumor Assays | 2014 |
Involvement of microRNA-24 and DNA methylation in resistance of nasopharyngeal carcinoma to ionizing radiation.
Topics: Animals; Azacitidine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cluster Analysis; Decitabine; Disease Models, Animal; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Male; Mice; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Radiation Tolerance; Radiation, Ionizing; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Kank1 reexpression induced by 5-Aza-2'-deoxycytidine suppresses nasopharyngeal carcinoma cell proliferation and promotes apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytoskeletal Proteins; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Real-Time Polymerase Chain Reaction; Tumor Suppressor Proteins | 2015 |
Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma; Case-Control Studies; Cell Proliferation; Cells, Cultured; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha Chains; Integrins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Nasopharynx; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Wnt Proteins | 2015 |
Epigenetic downregulation of the ISG15-conjugating enzyme UbcH8 impairs lipolysis and correlates with poor prognosis in nasopharyngeal carcinoma.
Topics: Adenosine Triphosphatases; Apoptosis; Azacitidine; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cytokines; Decitabine; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Kaplan-Meier Estimate; Lipase; Lipid Droplets; Lipolysis; Nasopharyngeal Neoplasms; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Ubiquitin-Conjugating Enzymes; Ubiquitins; Valosin Containing Protein | 2015 |
MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression.
Topics: Azacitidine; Carcinoma; Cell Growth Processes; Cell Line, Tumor; Cytidine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-myc; Transfection; Up-Regulation | 2011 |
Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Apoptosis Regulatory Proteins; Azacitidine; Carcinoma; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunohistochemistry; Male; Mice; Middle Aged; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Polymerase Chain Reaction; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; RNA, Messenger; Time Factors; Transfection; Tumor Suppressor Proteins; Young Adult | 2010 |
[Study on promoter methylation status of E-cadherin gene in nasopharyngeal carcinoma cell lines].
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Promoter Regions, Genetic | 2010 |
Demethylation of E-cadherin gene in nasopharyngeal carcinoma could serve as a potential therapeutic strategy.
Topics: Azacitidine; Biomarkers, Tumor; Cadherins; CpG Islands; Decitabine; DNA Modification Methylases; Down-Regulation; Humans; Methylation; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Transcription, Genetic; Tumor Cells, Cultured | 2011 |
TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma.
Topics: Azacitidine; Carcinoma; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Epigenesis, Genetic; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glycoproteins; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; RNA, Messenger | 2010 |
[Expression, genetic and epigenetic alterations of LTF gene in nasopharyngeal carcinoma cell lines].
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Deletion; Humans; Lactoferrin; Loss of Heterozygosity; Nasopharyngeal Neoplasms; Nasopharyngitis; Promoter Regions, Genetic; RNA, Messenger | 2010 |
MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway.
Topics: 3' Untranslated Regions; Adult; Aged; Azacitidine; Base Sequence; Cell Line; Cell Line, Tumor; Connexin 43; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Inhibitor of Apoptosis Proteins; Intercellular Signaling Peptides and Proteins; Male; MicroRNAs; Middle Aged; Molecular Sequence Data; Nasopharyngeal Neoplasms; Nerve Tissue Proteins; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Roundabout Proteins; Signal Transduction; Survivin | 2011 |
NOR1 is an HSF1- and NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Decitabine; DNA Methylation; Humans; Membrane Transport Proteins; Molecular Sequence Data; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2011 |
Protocadherin8 is a functional tumor suppressor frequently inactivated by promoter methylation in nasopharyngeal carcinoma.
Topics: Apoptosis; Azacitidine; Cadherins; Cell Adhesion; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Male; Middle Aged; Nasopharyngeal Neoplasms; Prognosis; Promoter Regions, Genetic; Protocadherins; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins; Wound Healing | 2012 |
LTBP-2 confers pleiotropic suppression and promotes dormancy in a growth factor permissive microenvironment in nasopharyngeal carcinoma.
Topics: Azacitidine; Carcinoma; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Latent TGF-beta Binding Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neovascularization, Pathologic; Promoter Regions, Genetic; Tumor Microenvironment; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor A | 2012 |
Genomic methylation profiling combined with gene expression microarray reveals the aberrant methylation mechanism involved in nasopharyngeal carcinoma taxol resistance.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Azacitidine; Carcinoma; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Profiling; Genomics; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel | 2012 |
[Effect of DNA hypermethylation on NOR1 promoter activity and expression].
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Cytosine Methylases; Epigenesis, Genetic; Gene Silencing; HL-60 Cells; Humans; Membrane Transport Proteins; Molecular Sequence Data; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; RNA, Messenger | 2012 |
5-aza-CdR induces the demethylation of Syk promoter in nasopharyngeal carcinoma cell.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Blotting, Western; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Primers; Humans; Intracellular Signaling Peptides and Proteins; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Real-Time Polymerase Chain Reaction; RNA, Messenger; Syk Kinase | 2012 |
Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinsing fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patient.
Topics: Azacitidine; Carcinoma; Case-Control Studies; Decitabine; DNA; DNA Methylation; DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; Humans; Mouth; Nasopharyngeal Neoplasms; Nuclear Proteins; Pharynx; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Sulfites; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma.
Topics: Adult; Aged; Azacitidine; Base Sequence; Carcinoma; Chromosomes, Human, Pair 3; CpG Islands; Cytoskeletal Proteins; Decitabine; DNA Methylation; DNA Primers; Enzyme Inhibitors; Genes, Tumor Suppressor; Humans; Middle Aged; Molecular Sequence Data; Mutagens; Mutation; Nasopharyngeal Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Sulfites; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma.
Topics: Adult; Aged; Animals; Azacitidine; Base Sequence; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Chromosomes, Human, Pair 11; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; DNA, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Immunoglobulins; Loss of Heterozygosity; Male; Membrane Proteins; Mice; Microsatellite Repeats; Middle Aged; Molecular Sequence Data; Mutation; Nasopharyngeal Neoplasms; Nasopharynx; Promoter Regions, Genetic; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Deletion; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors.
Topics: Antigens, Viral, Tumor; Azacitidine; Base Sequence; DNA Methylation; DNA-Cytosine Methylases; DNA, Viral; Enzyme Inhibitors; Herpesvirus 4, Human; Humans; Lymphoma, B-Cell; Nasopharyngeal Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic | 2004 |
RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma.
Topics: Animals; Azacitidine; Biomarkers, Tumor; Cell Cycle; Cell Division; Chromosomes, Human, Pair 3; Colony-Forming Units Assay; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Neoplasms; Nasopharynx; Reverse Transcriptase Polymerase Chain Reaction; Transduction, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2004 |
The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.
Topics: Alleles; Animals; Azacitidine; Base Sequence; Carcinoma; Cell Line; Cell Line, Tumor; Cell Transformation, Viral; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Deletion; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Mice; Mice, Nude; Molecular Sequence Data; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protein Binding; Stress, Physiological; Tumor Suppressor Proteins | 2004 |
Aberrant methylation of RASSF4/AD037 in nasopharyngeal carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Gene Silencing; Humans; Molecular Sequence Data; Monomeric GTP-Binding Proteins; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Sequence Homology, Amino Acid; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2004 |
Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma.
Topics: Animals; Azacitidine; Cells, Cultured; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mediator Complex; Mice; Nasopharyngeal Neoplasms; Nasopharynx; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transplantation, Heterologous | 2005 |
Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma.
Topics: Adult; Aged; Animals; Azacitidine; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Middle Aged; Nasopharyngeal Neoplasms; Nasopharynx; Promoter Regions, Genetic; Retinoids; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular; Transplantation, Heterologous; Tumor Cells, Cultured | 2005 |
[Inhibitory effect of 5-Aza-2'-deoxycytidine on human nasopharyngeal carcinoma xenograft in nude mice].
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cell Proliferation; Death-Associated Protein Kinases; Decitabine; DNA Methylation; DNA Modification Methylases; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Neoplasms; Neoplasm Transplantation; RNA, Messenger | 2005 |
Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation.
Topics: Azacitidine; Cadherins; Carcinoma; Cell Movement; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Esophageal Neoplasms; Gene Silencing; Genes, Tumor Suppressor; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Protocadherins; Sequence Deletion; Transcription, Genetic | 2006 |
Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Blotting, Western; Carcinoma; Carrier Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; DNA, Complementary; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Signal Transduction; Transfection; Wnt Proteins | 2006 |
Effect of methylation-associated silencing of the death-associated protein kinase gene on nasopharyngeal carcinoma.
Topics: Adult; Aged; Animals; Apoptosis Regulatory Proteins; Azacitidine; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Death-Associated Protein Kinases; Decitabine; DNA Methylation; Female; Gene Silencing; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Molecular Sequence Data; Nasopharyngeal Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Xenograft Model Antitumor Assays | 2006 |
Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma.
Topics: Adenocarcinoma; Azacitidine; Carcinoma, Squamous Cell; Case-Control Studies; Cell Proliferation; Colony-Forming Units Assay; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Nasopharyngeal Neoplasms; Nasopharynx; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2007 |
Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Connexin 43; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Fluoresceins; Gap Junctions; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Nasopharyngeal Neoplasms; Promoter Regions, Genetic | 2007 |
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.
Topics: Adaptor Proteins, Signal Transducing; Animals; Azacitidine; Biomarkers, Tumor; Carcinoma; Cell Line; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Repressor Proteins; Tumor Suppressor Proteins; Wnt1 Protein | 2007 |
Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma.
Topics: Azacitidine; Base Sequence; Carcinoma; Cell Line, Tumor; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lactoferrin; Loss of Heterozygosity; Male; Middle Aged; Molecular Sequence Data; Mutation; Nasopharyngeal Neoplasms; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Host-cell-phenotype-dependent control of the BCR2/BWR1 promoter complex regulates the expression of Epstein-Barr virus nuclear antigens 2-6.
Topics: Antigens, Viral; Azacitidine; B-Lymphocytes; Base Sequence; Burkitt Lymphoma; DNA; Epstein-Barr Virus Nuclear Antigens; Gene Expression Regulation, Viral; Herpesvirus 4, Human; In Vitro Techniques; Methylation; Molecular Sequence Data; Nasopharyngeal Neoplasms; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; RNA, Messenger; RNA, Viral | 1992 |
The role of methylation in the phenotype-dependent modulation of Epstein-Barr nuclear antigen 2 and latent membrane protein genes in cells latently infected with Epstein-Barr virus.
Topics: Antigens, Viral; Azacitidine; Cell Line; DNA Probes; DNA Replication; Enhancer Elements, Genetic; Epstein-Barr Virus Nuclear Antigens; Gene Expression Regulation, Viral; Genes, Viral; Herpesvirus 4, Human; Humans; Lymphocytes; Membrane Proteins; Methylation; Nasopharyngeal Neoplasms; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Viral Proteins; Viral Structural Proteins | 1989 |