azacitidine has been researched along with Cancer of Lung in 205 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (7.32) | 18.7374 |
| 1990's | 10 (4.88) | 18.2507 |
| 2000's | 73 (35.61) | 29.6817 |
| 2010's | 101 (49.27) | 24.3611 |
| 2020's | 6 (2.93) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, J; Cheng, Y; He, F; Mao, W; Peng, F; Xie, B; Zhou, Z | 1 |
| Al Homsi, U; Al-Zaidan, L; Assami, L; Bedhiafi, T; Dermime, S; Elashi, AA; Elkord, E; Fernandes, Q; Hydrose, SP; Inchakalody, VP; Khan, AQ; Krishnankutty, R; Maalej, KM; Merhi, M; Mestiri, S; Moustafa, D; Raza, A; Sasidharan Nair, V; Taib, N; Taleb, S; Therachiyil, L; Uddin, S; Yoosuf, ZSKM | 1 |
| Althouse, S; Gentzler, R; Jalal, SI; Kalra, M; Mamdani, H; Perkins, S; Wei, CX | 1 |
| Badenoch, A; Belinsky, SA; Burke, M; Dubose, D; Dye, WW; Grimes, MJ; Kuehl, PJ; Mallis, LM; March, TH; Picchi, MA; Revelli, DA; Sniegowski, T; Tellez, CS; Tessema, M; Vodak, DT | 1 |
| Fu, L; Hu, L; Hu, M; Zheng, B | 1 |
| Bhagat, TD; Cheng, H; Fan, N; Gucalp, R; Halmos, B; Kim, M; Perez-Soler, R; Piperdi, B; Shah, CD; Spivack, SD; Verma, A; Zou, Y | 1 |
| Liu, Y; Luo, F; Tu, L; Wang, Y; Zhang, N; Zhao, M | 1 |
| Ding, Z; Huang, JA; Lei, Z; Li, W; Liu, Z; Qin, H; Shen, D; Zeng, Y; Zhu, J | 1 |
| Ming, F; Sun, Q | 1 |
| Anagnostou, V; Ballew, M; Baylin, SB; Chiappinelli, KB; DeStefano Shields, CE; Hellmann, MD; Hicks, J; Niknafs, N; Stone, M; Strick, R; Strissel, PL; Topper, MJ; Tran, PT; Vaz, M; Velculescu, VE; Wenzel, A; Yen, RC; Zahnow, CA | 1 |
| Chen, Y; Rong, X; Su, L; Zhang, X | 1 |
| Gu, J; Liu, H; Wang, G; Xiong, C | 1 |
| Fan, Y; Guo, F; Song, D; Sun, Q; Wang, J; Wang, L; Zhang, D; Zhang, Q; Zhang, W | 1 |
| Chen, H; Ding, X; Hua, CS; Ma, DC; Wang, WS; Wu, F; Zhang, CD; Zhao, J | 1 |
| Besse, B; Domine Gomez, M; Fandi, A; Felip, E; Garassino, MC; Garrido, P; Giaccone, G; Levy, BP; MacBeth, KJ; Menezes, D; Paz-Ares, L; Piperdi, B; Ponce-Aix, S; Risueño, A; Slepetis, R; Wu, X | 1 |
| Chami, H; Kadara, H; Khalil, A; Nehme, E; Nemer, G; Rahal, Z; Sinjab, A | 1 |
| Chen, D; Chen, LH; Dong, JY; Hu, KF; Liu, J; Peng, H; Wu, WB; Yang, XL; Zhao, YN | 1 |
| Cao, HX; Feng, JF; Li, XY; Ma, R; Wu, JQ; Wu, JZ; Zhong, YJ | 1 |
| Arai, E; Betsuyaku, T; Kanai, Y; Kohno, T; Sato, T; Soejima, K; Tsuta, K; Watanabe, S | 1 |
| Choi, YH; Kim, GY; Kim, WJ; Shin, DY; Sung Kang, H; Yoo, YH | 1 |
| Dong, YQ; Ji, T; Liang, JS; Xu, JH; Yin, GL; Zhang, XM; Zhu, SB | 1 |
| Belinsky, SA; Cheng, YS; Grimes, MJ; Kuehl, PJ; March, TH; Picchi, MA; Reed, MD; Tellez, CS; Tessema, M | 1 |
| Cui, W; Huang, HQ; Li, N; Zhang, GS | 1 |
| Cao, J; Chen, HQ; Han, F; Jiang, X; Li, YH; Liu, JY; Liu, WB; Liu, Y | 1 |
| Baylin, SB; Brahmer, JR; Brock, MV; Carvajal, RD; Demeyer, T; Du, Z; Easton, K; Easwaran, H; Jones, PA; Juergens, RA; Koch, A; Laird, PW; Mohammad, HP; Pardoll, D; Parsana, P; Rodgers, K; Rudin, CM; Taube, JM; Topalian, SL; Tsai, S; Tykodi, SS; Vancriekinge, W; Vendetti, F; Wang, W; Weisenberger, DJ; Wrangle, J; Yen, RW; Zahnow, CA | 1 |
| Han, J; Heo, K; Hong, SH; Hwang, JA; Kim, DH; Kim, Y; Kim, YH; Lee, BB; Lee, YS; Park, SE; Shim, YM | 1 |
| Cho, YG; Han, J; Han, JY; Hong, SH; Hwang, JA; Kim, DH; Kim, Y; Kim, YH; Lee, J; Lee, YS; Shim, YM | 1 |
| Berdel, WE; Dugas, M; Haase, AK; Hascher, A; Hebestreit, K; Jungen, D; Klein, HU; Müller-Tidow, C; Ogawa, S; Rius, M; Rohde, C; Schulze, I; Stoll, M; Thoennissen, NH; Tickenbrock, L; Wiewrodt, R; Witten, A | 1 |
| Han, L; Hu, Y; Li, X; Tao, H; Wang, J; Yang, B; Zhang, S | 1 |
| Hu, RC; Liu, JJ; Liu, WE; Tan, SX; Tan, YL | 2 |
| Baylin, SS; Belinsky, SA; Liu, Y; Tellez, CS; Tessema, M; Van Neste, L; Yingling, CM | 1 |
| Bi, J; Gao, M; Ma, T; Song, B; Wang, Y; Zhang, C; Zhou, Y | 1 |
| Dong, QZ; Liu, Y; Miao, Y; Wang, EH; Wang, L; Wang, S; Xu, HT | 1 |
| Barankiewicz, J; Bednarek, W; Boon, L; Gabrysiak, M; Golab, J; Hamblin, MR; Mroz, P; Muchowicz, A; Rygiel, T; Wachowska, M | 1 |
| Chen, L; Huang, G; Ren, J; Song, H; Wang, R | 1 |
| Belinsky, SA; Grimes, MJ; Liu, Y; March, TH; Oganesian, A; Picchi, MA; Reed, MD; Taverna, P; Tellez, CS | 1 |
| Chen, LB; Guan, XX; Lu, XX; Tong, JD; Wang, JZ; Wang, Z; Zhang, YW; Zheng, Y | 1 |
| Mjoli, PB; Poolman, T; Ray, DW; Singh, N; Sommer, P; Taylor, K | 1 |
| Levine, A; Sun, Y; Yi, L | 1 |
| Liang, Y; Perez-Soler, R; Qiu, X; Sellers, RS; Zou, Y | 2 |
| Becker, N; Effenberger, K; Esteller, M; Hagmann, W; Izbicki, JR; Kemming, D; Kim, SZ; Lamszus, K; Pantel, K; Riethdorf, S; Risch, A; Sandoval, J; Uzunoglu, FG; Westphal, M; Wikman, H; Wrage, M | 1 |
| Fan, C; Jiang, G; Lin, X; Liu, Y; Miao, Y; Wang, E; Wang, L; Xu, X; Yu, J; Zhang, X; Zhang, Y | 1 |
| Baylin, SB; Dobromilskaya, I; Easwaran, H; Huang, P; Poirier, JT; Rudin, CM; Topper, M; Vendetti, FP; Wrangle, J | 1 |
| Berdel, WE; Edemir, B; Füller, M; Göllner, S; Klein, M; Müller-Tidow, C; Qianli, J; Rohde, C; Schmidt, E; Schulze, I; Tschanter, P | 1 |
| Chiyomaru, T; Enokida, H; Goto, Y; Higashimoto, I; Inoue, H; Mataki, H; Matsushita, R; Mizuno, K; Nakagawa, M; Nishikawa, R; Samukawa, T; Seki, N | 1 |
| Drzewiecka, H; Dyszkiewicz, W; Gałęcki, B; Jagodziński, PP; Jarmołowska-Jurczyszyn, D; Kluk, A | 2 |
| Chen, WZ; Chen, XY; Huang, SH; Liu, JM; Liu, ZL; Long, XH; Peng, AF; Zhang, ZH; Zhou, YF | 1 |
| Dai, SP; Ding, N; Han, L; Han, YW; Xie, C; Zhang, YJ | 1 |
| Abdel-Wahab, AH; Al Homssi, A; Al-Tel, T; Al-Tunaiji, H; El-Awady, RA; El-Serafi, A; Hersi, F; Saleh, EM; Suhail, M | 1 |
| Cao, J; Chen, HQ; Han, F; Huang, C; Jiang, X; Li, YH; Liu, JY; Liu, WB; Liu, Y; Zhao, H | 1 |
| Liu, S; Molina, JR; Pang, J; Shen, N; Yan, F; Yang, P | 1 |
| Choi, SY; Han, DH; Hong, SH; Kang, JH; Kang, N; Kim, SJ; Kim, YK; Kim, YS; Lee, DS; Lee, KY; Park, JK; Park, JY; Park, MS; Sung, SW; Yim, HW; Yoo, IeR | 1 |
| Qi, X; Wang, W; Wu, M | 1 |
| Ditzel, HJ; Gjerstorff, MF; Maheswaran, E; Pedersen, CB | 1 |
| Akman, B; Baylin, SB; Beckmann, MW; Budhu, S; Buhu, S; Chan, TA; Chiappinelli, KB; Cope, LM; Desrichard, A; Hein, A; Henke, C; Li, H; Makarov, V; Merghoub, T; Mergoub, T; Pardoll, DM; Rote, NS; Slamon, DJ; Snyder, A; Strick, R; Strissel, PL; Wolchok, JD; Zahnow, CA | 1 |
| Dong, Y; Ji, T; Liang, J; Ma, Z; Xiao, Y; Yin, G | 1 |
| Bintz, J; Garcia, MN; Grasso, D; Iovanna, JL; Lomberk, G; Loncle, C; Lopez, MB; Molejon, MI; Urrutia, R | 1 |
| Gao, B; Li, GH; Shao, GG; Yang, B; Yang, ZG | 1 |
| Weintraub, K | 1 |
| Brown, H; Chresta, CM; Delpuech, O; Taylor, MA; Wappett, M | 1 |
| Ginat, R; Maman, S; Meshel, T; Naftali, O; Sagi-Assif, O; Witz, IP | 1 |
| Carter, CA; Day, RM; Lybeck, M; Oronsky, A; Oronsky, B; Oronsky, N; Richard, P; Scicinski, J; Zeman, K | 1 |
| Jelicks, L; Liang, Y; Liu, J; Ma, S; Mei, J; Perez-Soler, R; Zeng, J; Zou, Y | 1 |
| Chen, S; Huang, W; Li, Y; Liu, R; Mao, X; Shi, W; Shuai, W; Wu, J; Ye, Z; Zhuang, L; Zuo, Z | 1 |
| Condom, E; Esteller, M; Gomez, A; Moran, S; Romero, OA; Sanchez-Cespedes, M; Torres-Diz, M; Verdura, S; Villanueva, A | 1 |
| Kim, MC; Kim, NY; Kim, Y | 1 |
| Du, Z; Feng, X; Lai, Q; Li, A; Liu, B; Song, J; Sun, X; Wang, H; Xu, Y | 1 |
| Du, W; Huang, JA; Lei, Z; Liu, Z; Qian, Q; Qin, H; Shen, D; Zeng, Y; Zhu, J | 1 |
| Akizuki, R; Endo, S; Hichino, A; Ikari, A; Matsunaga, T; Okamoto, M; Taga, S | 1 |
| Hu, FH; Huang, WJ; Jen, J; Liao, SY; Lin, P; Lu, YH; Shieh, JM; Tang, YA; Wang, TW; Wang, YC; Wang, YJ; Yeh, YL | 1 |
| An, J; Ji, F; Jiao, H; Sun, H; Wang, R; Zhou, D | 1 |
| Chai, G; Chen, Y; Hu, YG; Li, L; Lu, S; McNutt, MA; Otterson, GA; Wang, D; Wang, H; Wu, L; Wu, X; Yang, Y; Yu, Y; Zhao, Y; Zhou, W; Zhu, WG | 1 |
| Albertus, DL; Beer, DG; Bigbee, WL; Chang, AC; Chen, G; Chinnaiyan, AM; Giordano, TJ; Hartojo, W; Lin, L; Orringer, MB; Seder, CW; Silvers, A; Thomas, DG; Wang, X | 1 |
| Chen, Z; Gao, L; Gu, B; Pan, S; Shu, Y; Wang, F; Xu, J; Yang, D; Zhang, L | 1 |
| Cha, SI; Chae, MH; Choi, JE; Jheon, S; Jung, TH; Kim, CH; Kim, DS; Kim, EJ; Park, JY | 1 |
| Liao, W; McNutt, MA; Zhu, WG | 1 |
| Ao, L; Cao, J; Cui, ZH; Liu, JY; Liu, WB; Yang, H; Zhou, YH; Zhou, ZY | 1 |
| Krynetskaia, NF; Krynetskiy, E; Mishra, AK; Phadke, MS | 1 |
| Al-Sarraf, N; Baird, AM; Cathcart, MC; Gray, SG; McGovern, E; O'Byrne, KJ | 1 |
| Aki, N; Emoto, N; Kage, H; Kusakabe, M; Nagase, T; Nakajima, J; Ohishi, N; Takai, D; Watanabe, K; Yatomi, Y | 1 |
| Belda-Iniesta, C; Cejas, P; Cortes-Sempere, M; de CastroCarpeño, J; Ibanez de Caceres, I; López-Ríos, F; Machado-Pinilla, R; Manguán-García, C; Moratilla, C; Nistal, M; Paz-Ares, L; Perona, R; Rodriguez-Fanjul, V | 1 |
| Chen, BH; Hsu, HS; Lee, SH; Tsai, WC; Tseng, RC; Tzao, C; Wang, YC | 1 |
| Li, HL; Ma, AN | 1 |
| Bartling, B; Hofmann, HS; Rehbein, G; Silber, RE; Simm, A | 1 |
| Ishii, J; Kashiwagi, K; Kitamura, H; Masuda, M; Mitsui, H; Ogura, T; Ohmori, T; Okudela, K; Oshiro, H; Sakaeda, M; Sato, H; Shimoyamada, H; Suzuki, T; Tajiri, M; Woo, T; Yazawa, T | 1 |
| Gao, J; Ming, S; Sun, T | 1 |
| Borden, EC; Cheriyath, V; Luszczek, W; Mekhail, TM | 1 |
| Mahesh, S; Perez-Soler, R; Qiu, X; Saxena, A; Zou, Y | 1 |
| Ao, L; Cao, J; Cui, ZH; Liu, JY; Liu, WB; Xiang, YL; Yuan, XY; Zhou, YH; Zhou, ZY | 1 |
| Baylin, SB; Belinsky, SA; Casero, RA; Channell, MM; Grimes, MJ; Liu, Y; March, TH; Mitchell, HD; Picchi, MA; Reed, MD; Stidley, CA; Tellez, CS; Tesfaigzi, Y | 1 |
| Hsu, CP; Ko, JL; Lai, CH; Liu, YF; Tang, LC; Tang, SC; Wong, RH; Wu, MF | 1 |
| Ding, Q; Ding, YB; Liu, XA; Liu, YX; Shi, JP; Wang, S; Xia, JG; Xia, TS; Zhao, Y | 1 |
| Al-Sohaily, S; Cooper, WA; Kennedy, CW; Kohonen-Corish, MR; McCaughan, BC; Mladenova, DN; Pangon, L; Selinger, CI; Stirzaker, C | 1 |
| Hoshino, H; Moriya, Y; Okamoto, T; Suzuki, M; Tamura, H; Yoshida, S; Yoshino, I | 1 |
| Kaminskyy, VO; Surova, OV; Vaculova, A; Zhivotovsky, B | 1 |
| Hu, CH; Wu, F | 1 |
| Kay, P; Matthews, L; Ray, D; Schlossmacher, G; Singh, D; Sommer, P; White, A | 1 |
| Li, L; Liu, X; Tu, B; Wang, D; Wang, H; Wang, L; Zheng, Z; Zhu, WG | 1 |
| Cao, B; Guo, M; Hoque, MO; Jia, Y; Yang, Y; Yin, D; Yu, Y | 1 |
| Li, Q; Tainsky, MA | 1 |
| Haugen, A; Mollerup, S; Skaug, V; Stangeland, L; Tekpli, X; Zienolddiny, S | 1 |
| Altenberger, C; Arns, BM; Babinsky, V; Döme, B; End-Pfützenreuter, A; Grin, Y; Heller, G; Klepetko, W; Lang, G; Minichsdorfer, C; Noll, C; Weinzierl, M; Ziegler, B; Zielinski, CC; Zöchbauer-Müller, S | 1 |
| Kelley, N; Tennis, MA; Vanscoyk, MM; Wilson, LA; Winn, RA | 1 |
| Chang, YL; Hong, TM; Jou, YS; Lin, JC; Lin, TC; Wu, CT; Wu, JY; Wu, YY; Yang, PC | 1 |
| Chie, EK; Kim, HJ; Kim, IA; Kim, IH; Kim, JH; Young, PD | 1 |
| Baylin, SB; Belinsky, SA; Brock, MV; Coleman, B; Delgado, IE; Franco, N; Herman, JG; Hooker, CM; Juergens, RA; Lee, B; Murphy, SC; Rodgers, K; Rudek, MA; Rudin, CM; Sebree, R; Tsai, S; Vendetti, FP; Wrangle, J; Zhao, M | 1 |
| Deng, T; Liu, J; Luo, HS; Wang, FL; Xie, YS; Zhang, LJ; Zhang, Y | 1 |
| Brock, MV; Guo, M; Herman, JG; Liu, X; Zhan, Q; Zhang, X | 1 |
| Bermejo, JL; Claus, R; Dienemann, H; Gu, L; Jacobsson, H; Meister, M; Muley, T; Peil, B; Plass, C; Risch, A; Sarkisyan, N; Scherf, DB | 1 |
| Aimiuwu, J; Chan, KK; Chu, BF; Grever, MR; Karpenko, MJ; Liu, Z; Otterson, GA; Villalona-Calero, MA | 1 |
| Ao, L; Cao, J; Chen, HQ; Cui, ZH; Han, F; Jiang, X; Li, YH; Liu, JY; Liu, WB; Liu, Y; Yang, LJ | 1 |
| Fang, HL; Jin, YT; Yu, ZC; Zhu, HB | 1 |
| Jiang, GY; Li, QC; Wang, EH; Xu, HT; Xu, K; Yang, LH; Zhang, XP; Zhao, HY | 1 |
| Battistini, A; Belardelli, F; Fragale, A; Gabriele, L; Lucarini, V; Mattei, F; Sanchez, M; Scala, S; Schiavoni, G; Sestili, P; Sistigu, A; Spada, M; Spadaro, F | 1 |
| Fukuyama, Y; Gazdar, AF; Minna, JD; Tockman, MS; Toyooka, S; Wistuba, II | 1 |
| Boivin, AJ; Hurtubise, A; Momparler, LF; Momparler, RL | 1 |
| Chen, Z; Cheng, X; Wu, Y; Zhu, B | 1 |
| Chang, JW; Chen, CY; Chen, JT; Lin, RK; Lu, YP; Shih, CM; Tseng, RC; Wang, YC | 1 |
| Alder, H; Croce, CM; Kaiser, LR; Kuroki, T; Matsuyama, A; Trapasso, F; Williams, NN; Yendamuri, S | 1 |
| Borczuk, AC; Brody, JS; Busch, S; Capurro, M; D'Armiento, JM; Filmus, J; Kim, H; Lange, J; Powell, CA; Rothman, PB; Xu, GL | 1 |
| Brambilla, E; Gazdar, AF; Minna, JD; Padar, A; Sathyanarayana, UG; Takahashi, T; Toyooka, S | 1 |
| Baylin, SB; Belinsky, SA; Crume, KP; Esteller, M; Grimes, MJ; Joste, N; Palmisano, WA; Toyota, M; Winters, SA | 1 |
| Gazdar, AF; Lam, S; Miyajima, K; Padar, A; Reddy, JL; Sathyanarayana, UG; Shivapurkar, N; Tockman, MS; Toyooka, KO; Toyooka, S; Toyota, M | 1 |
| Euhus, DM; Gazdar, AF; Heda, S; Lewis, C; Minna, JD; Rathi, A; Roth, JA; Sugio, K; Takahashi, T; Tonk, V; Virmani, A | 1 |
| Baylin, SB; Belinsky, SA; Herman, JG; Issa, JP; Klinge, DM; March, TH; Stidley, CA | 1 |
| Honoki, K; Mii, Y; Mori, T; Takakura, Y; Tsujiuchi, T; Tsutsumi, M; Yoshitani, K | 1 |
| Schrump, DS | 1 |
| Hurtubise, A; Momparler, RL | 1 |
| Heasley, LE; Winn, RA | 1 |
| Branch, C; Gomyo, Y; Mukhopadhyay, T; Roth, JA; Sasaki, J | 1 |
| Chen, Y; Deutschmann, N; Hühn, D; Knösel, T; Pacyna-Gengelbach, M; Petersen, I | 1 |
| Hong, WK; Mao, L; Sun, SY; Tang, X; Wistuba, II; Wu, W | 1 |
| Fujisawa, T; Gazdar, AF; Iizasa, T; Sathyanarayana, UG; Shigematsu, H; Shivapurkar, N; Suzuki, M; Takahashi, T | 1 |
| Beer, DG; Chen, GA; Fischette, MR; Guo, ZS; Hong, JA; Kassis, ES; Lee, S; Nguyen, DM; Schrump, DS; Steiner, FA; Trepel, JB; Weiser, TS | 1 |
| Kim, JS; Kim, YH; Whang, YM; Yoo, YD | 1 |
| Fushiki, S; Ito, K; Itoh, K; Nishimura, M; Nishiyama, K; Sakakura, C; Shimada, J; Terauchi, K; Yanada, M; Yaoi, T | 1 |
| Horio, Y; Osada, H; Sugito, N; Takahashi, T; Tatematsu, Y | 1 |
| End-Pfützenreuter, A; Fong, KM; Gazdar, AF; Girard, L; Heller, G; Lang, G; Minna, JD; Seidl, S; Zielinski, CC; Zöchbauer-Müller, S | 1 |
| Lippman, SM; Sabichi, AL; Xu, X | 1 |
| Biddle, A; Bounds, R; Dmitrovsky, E; Dragnev, KH; Freemantle, SJ; Li, N; Ma, Y; Nitkin, C; Petty, WJ | 1 |
| Chang, CW; Chen, RA; Chen, SC; Chen, YH; Cheng, CY; Chou, MC; Fang, HY; Hsu, LS; Lee, CH; Lin, CY; Lin, TS; Tai, HL | 1 |
| Ajima, R; Fujiwara, T; Kohno, T; Minna, JD; Sasaki, H; Takahashi, K; Tanaka, N; Yokota, J | 1 |
| Brena, RM; Lang, JC; Lin, M; Morrison, CD; Otterson, GA; Plass, C; Schuller, DE; Smiraglia, DJ; Smith, LT | 1 |
| Chen, GA; Guo, ZS; Hong, JA; Irvine, KR; Liu, Y; Nguyen, DM; Restifo, NP; Schrump, DS; Spiess, PJ; Wunderlich, JR; Zeng, G | 1 |
| Brena, RM; Hackanson, B; Morrison, C; Otterson, GA; Plass, C; Tada, Y | 1 |
| Ando, S; Chen, H; Iida, T; Kimura, H; Nakagawara, A; Nakajima, T; Nakamura, Y; Ohira, M; Suzuki, M | 1 |
| Belinsky, SA; Hutt, JA; Vuillemenot, BR | 1 |
| Chen, H; Costa, M; Ke, Q; Kluz, T; Yan, Y | 1 |
| Berenguer, J; Borczuk, AC; Hei, TK; Powell, CA; Shao, G; Zhao, Y | 1 |
| Cantor, JP; Collins, JE; Druck, T; Friedberg, JS; Han, SY; Huebner, K; Iliopoulos, D; Lakshman, TV; McCorkell, KA; Rao, AS; Semba, S; Wachsberger, P | 1 |
| Chen, GA; Figg, WD; Fischette, MR; Hancox, A; Hong, JA; Kunst, TF; Li, X; Murgo, AJ; Nguyen, DM; Pishchik, V; Schrump, DS; Steinberg, SM; Zhao, M | 1 |
| Fields, CR; Pan, YX; Robertson, KD; Su, N; Zhong, S | 1 |
| Euhus, DM; Fong, KM; Gao, B; Gazdar, AF; Gerald, W; Girard, L; Jiang, A; Kim, YH; Lam, CL; Lewis, CM; Minna, JD; Nanda, R; Olopade, OI; Perou, CM; Pollack, JR; Sato, M; Shames, DS; Shay, JW; Shivapurkar, N; Shyr, Y; Wong, M | 1 |
| Fujisawa, T; Gazdar, AF; Iizasa, T; Minna, JD; Shames, DS; Shigematsu, H; Shivapurkar, N; Sunaga, N; Suzuki, M; Takahashi, T | 1 |
| Chang, HC; Cho, CY; Hung, WC | 1 |
| Chen, Y; Deutschmann, N; Knösel, T; Kotb, WF; Lund, P; Pacyna-Gengelbach, M; Petersen, I; Schlüns, K; Sers, C; Usui, T; Yasumoto, H; Ye, F | 1 |
| Nguyen, DM; Schrump, DS | 1 |
| Angeloni, D; Braga, E; Danilkovitch-Miagkova, A; Ivanova, T; Lerman, MI; Zabarovsky, E | 1 |
| Chen, CY; Cheng, YW; Lee, H; Tsai Chang, JH; Wu, TC; Wu, YH | 1 |
| Chen, D; Cheng, L; Gao, L; Lu, ZH; Pan, SY; Shu, YQ; Xie, EF; Yang, D; Zhang, JN; Zhang, LX | 1 |
| Dacic, S; Guo, M; Landreneau, R; Siegfried, JM; Sun, Q; Yu, J; Yue, W; Zhang, L; Zhou, W | 1 |
| Clanet, C; Favre, G; He, B; Jablons, D; Marty-Detraves, C; Mazières, J; Nieto-Acosta, J; Pradines, A; Tovar, D | 1 |
| Hsu, HS; Hsu, WH; Lin, RK; Tseng, C; Tseng, RC; Wang, YC; Wen, CK | 1 |
| Eblin, KE; Futscher, BW; Gandolfi, AJ; Jensen, TJ; Novak, P | 1 |
| Chahinian, AP; Greenfield, DS; Holland, JF; Ohnuma, T | 1 |
| Carr, BI; Reilly, JG; Riggs, A; Smith, SS; Winberg, C | 1 |
| Crowley, JJ; Goodwin, JW; Livingston, RB; Panella, TJ; Williamson, SK | 1 |
| Chen, W; Coxon, AB; Kaye, FJ; Khleif, SN; Otterson, GA | 1 |
| Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D | 1 |
| Côté, S; Momparler, RL | 1 |
| Baylin, SB; Belinsky, SA; Herman, JG; Middleton, SK; Nikula, KJ; Palmisano, WA; Swafford, DS; Tesfaigzi, J | 1 |
| Ayoub, J; Belanger, K; Bouffard, DY; Dionne, J; Momparler, LF; Momparler, RL | 1 |
| Culp, LA; Kogerman, P; Sy, MS | 1 |
| Concha, A; Garrido, F; Hortas, ML; Morell, M; Redondo, M; Ruiz-Cabello, F; Serrano, A | 1 |
| Crist, KA; Kelloff, GJ; Lantry, LE; Lubet, RA; Wang, Y; You, M; Zhang, Z | 1 |
| Ayoub, J; Eliopoulos, N; Momparler, RL | 1 |
| DiLeone, L; Filho, AF; Garbino, C; Gorini, CN; Mans, DR; Muse, I; Sabini, G; Schunemann, H; Schwartsmann, G | 1 |
| Anna, CH; Barrett, JC; Devereux, TR; Foley, JF; Patel, AC; Stockton, PS; Tyson, FL | 1 |
| Chen, GA; Fischette, MR; Guo, ZS; Hong, JA; Nguyen, DM; Ohnmacht, GA; Schrump, DS; Weiser, TS | 1 |
| Beal, MD; Lakshmanan, RR; Otterson, GA; Zhu, WG | 1 |
| Ashfaq, R; Fong, KM; Gazdar, AF; Geradts, J; Lam, S; Maitra, A; Milchgrub, S; Minna, JD; Virmani, AK; Zöchbauer-Müller, S | 1 |
| Miki, K; Shimizu, E; Sone, S; Tani, K; Yano, S | 1 |
| Feng, G; Lotan, R; Xu, X; Youssef, EM | 1 |
| Ayoub, J; Momparler, RL | 1 |
| Dai, Z; Ding, H; Duan, W; Hall, J; Otterson, GA; Plass, C; Srinivasan, K; Villalona-Calero, MA; Zhu, WG | 1 |
| Issa, JP; Kemp, BL; Khuri, FR; Kurie, JM; Lee, HY; Lee, JI; Liu, DD; Mao, L; Soria, JC; Wang, L | 1 |
| Dallol, A; Forgacs, E; Kishida, T; Latif, F; Maher, ER; Martinez, A; Minna, JD; Rabbitts, P; Sekido, Y; Walker, R | 1 |
| Chahinian, AP; Holland, JF; Mandel, EM; Suzuki, Y | 1 |
| Azumi, N; Benfield, JR; Gabriel, A; Hammond, WG; Hill, LR; Teplitz, RL; Yellin, A | 1 |
| Geber, E; Lehmacher, W; Schmahl, W | 1 |
| Greig, R; Kline, T; Mallon, F; Poste, G; Trainer, DL | 1 |
| Everett, CA; Hart, IR; Ormerod, EJ | 1 |
| Lieberman, AP; Ware, JL; Webb, KS | 1 |
| Takenaga, K | 1 |
| Asmeron, Y; Blayney, D; Carr, BI; Doroshow, JH; Goldberg, D; Leong, L; Rahbar, S | 1 |
| Carr, DT; Dhingra, HM; Holoye, PY; Lee, JS; Murphy, WK; Umsawasdi, T | 1 |
| Bufalari, A; Cavaliere, A; Vitali, R | 1 |
| Diamant, M; Due, C; Olsson, L | 1 |
| Behnke, O; Olsson, L; Sørensen, HR | 1 |
| Carter, SK | 1 |
| Carter, SK; Slavik, M | 1 |
7 review(s) available for azacitidine and Cancer of Lung
| Article | Year |
|---|---|
Chronic myelomonocytic leukemia (CMML)-0 with pleural effusion as first manifestation: A case report.
Topics: Adult; Antineoplastic Agents; Azacitidine; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Lung Neoplasms; Pleural Effusion; Tomography, X-Ray Computed | 2020 |
Addressing the elephant in the room, therapeutic resistance in non-small cell lung cancer, with epigenetic therapies.
Topics: Antibodies, Monoclonal; Azacitidine; Azetidines; Benzamides; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; CpG Islands; Disease Progression; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Histones; Humans; Hydralazine; Immunotherapy; Lung Neoplasms; Molecular Targeted Therapy; Mutation; Neoplasm Recurrence, Local; Nitro Compounds; Nivolumab; Prognosis; Pyridines; Treatment Outcome; Valproic Acid | 2016 |
Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716.
Topics: Anemia, Sickle Cell; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Decitabine; Humans; Leukemia; Lung Neoplasms; Male; Prostatic Neoplasms | 2003 |
Genomic surgery for lung cancer.
Topics: Animals; Antineoplastic Agents; Azacitidine; Chromatin Assembly and Disassembly; Decitabine; Depsipeptides; DNA Methylation; Gene Expression Regulation, Neoplastic; Genetic Engineering; Histone Deacetylases; Humans; Lung Neoplasms; Peptides, Cyclic | 2004 |
Targeting the epigenome for the treatment of thoracic malignancies.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Chromatin; Decitabine; Depsipeptides; Drug Evaluation, Preclinical; Epigenesis, Genetic; Humans; Lung Neoplasms | 2006 |
Evaluation of an inhibitor of DNA methylation, 5-aza-2'-deoxycytidine, for the treatment of lung cancer and the future role of gene therapy.
Topics: Animals; Antibiotics, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Decitabine; DNA Methylation; DNA Modification Methylases; Evaluation Studies as Topic; Forecasting; Genetic Therapy; Humans; Lung Neoplasms | 2000 |
Modification of the metastatic potential of tumor cells by drugs.
Topics: Animals; Azacitidine; Butyrates; Butyric Acid; Carcinoma; Cell Division; Cell Line; Cells, Cultured; Dimethyl Sulfoxide; Lung Neoplasms; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Cells, Circulating; Phenotype | 1986 |
9 trial(s) available for azacitidine and Cancer of Lung
| Article | Year |
|---|---|
A Brief Report of a Phase II trial Evaluating Efficacy and Safety of Hypomethylating Agent Guadecitabine in Combination With Carboplatin in Extensive Stage Small Cell Lung Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Humans; Lung Neoplasms; Small Cell Lung Carcinoma | 2023 |
Randomised phase 2 study of pembrolizumab plus CC-486 versus pembrolizumab plus placebo in patients with previously treated advanced non-small cell lung cancer.
Topics: Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Progression-Free Survival; Survival Rate; Treatment Outcome | 2019 |
Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzamides; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Combined Modality Therapy; Disease Progression; Disease-Free Survival; DNA Methylation; Epigenesis, Genetic; Female; Genetic Therapy; Histones; Humans; Lung Neoplasms; Male; Middle Aged; Pyridines | 2011 |
Phase I study of 5-aza-2'-deoxycytidine in combination with valproic acid in non-small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Non-Small-Cell Lung; Decitabine; Dose-Response Relationship, Drug; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Treatment Outcome; Valproic Acid | 2013 |
Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura.
Topics: Adult; Aged; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Decitabine; DNA Modification Methylases; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Membrane Proteins; Mesothelioma; Middle Aged; Neoplasm Proteins; Pleural Neoplasms; Transcriptional Activation | 2006 |
Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; CpG Islands; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Down-Regulation; Epigenesis, Genetic; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoenzyme Techniques; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Proteins; Nerve Tissue Proteins; Promoter Regions, Genetic; Receptor Activity-Modifying Protein 2; Receptor Activity-Modifying Proteins; Receptors, Immunologic; Roundabout Proteins; Tumor Cells, Cultured | 2007 |
Phase II trial and cost analysis of fazarabine in advanced non-small cell carcinoma of the lung: a Southwest Oncology Group study.
Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1995 |
Pilot phase I-II study on 5-aza-2'-deoxycytidine (Decitabine) in patients with metastatic lung cancer.
Topics: Adult; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Decitabine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Tumor Cells, Cultured | 1997 |
A phase I trial of cisplatin plus decitabine, a new DNA-hypomethylating agent, in patients with advanced solid tumors and a follow-up early phase II evaluation in patients with inoperable non-small cell lung cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Decitabine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged | 2000 |
189 other study(ies) available for azacitidine and Cancer of Lung
| Article | Year |
|---|---|
DNA methylation influences the CTCF-modulated transcription of RASSF1A in lung cancer cells.
Topics: Azacitidine; CCCTC-Binding Factor; Cell Line, Tumor; DNA Methylation; Humans; Lung Neoplasms; Promoter Regions, Genetic; Transcription Factors; Tumor Suppressor Proteins | 2022 |
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR).
Topics: Antibodies; Antigens, Neoplasm; Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; Epigenesis, Genetic; Humans; Lung Neoplasms; Membrane Proteins | 2023 |
5-Azacytidine inhaled dry powder formulation profoundly improves pharmacokinetics and efficacy for lung cancer therapy through genome reprogramming.
Topics: Administration, Inhalation; Animals; Antigens, Neoplasm; Azacitidine; Demethylation; Drug Compounding; Epigenome; Humans; Lung Neoplasms; Male; Powders; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2020 |
First-in-human study of inhaled Azacitidine in patients with advanced non-small cell lung cancer.
Topics: Animals; Azacitidine; Carcinoma, Non-Small-Cell Lung; DNA Methylation; Humans; Lung Neoplasms; Mice; Neoplasm Recurrence, Local; Treatment Outcome | 2021 |
Decitabine reverses TGF-β1-induced epithelial-mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Survival; Decitabine; Epithelial-Mesenchymal Transition; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Neoplasms, Experimental; Transforming Growth Factor beta1; Tumor Cells, Cultured; Zinc Finger E-box-Binding Homeobox 1 | 2017 |
Methylated +322-327 CpG site decreases hOGG1 mRNA expression in non-small cell lung cancer.
Topics: 5' Untranslated Regions; 8-Hydroxy-2'-Deoxyguanosine; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Deoxyguanosine; DNA Glycosylases; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Sp1 Transcription Factor | 2017 |
Epigenetically silenced PTPRO functions as a prognostic marker and tumor suppressor in human lung squamous cell carcinoma.
Topics: Adult; Aged; Animals; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; CpG Islands; Decitabine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Heterografts; Humans; Lung Neoplasms; Male; Mice; Middle Aged; Prognosis; Receptor-Like Protein Tyrosine Phosphatases, Class 3 | 2017 |
Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer.
Topics: Animals; Antigen Presentation; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Therapy, Combination; Histone Deacetylase Inhibitors; Hydroxamic Acids; Immunotherapy; Lung Neoplasms; Mice; T-Lymphocytes; Transcriptome; Tumor Escape; Tumor Microenvironment | 2017 |
Methylation-mediated loss of SFRP2 enhances invasiveness of non-small cell lung cancer cells.
Topics: A549 Cells; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Movement; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; Membrane Proteins; Neoplasm Invasiveness; Promoter Regions, Genetic; Signal Transduction; Zinc Finger E-box-Binding Homeobox 1 | 2018 |
SATB2 targeted by methylated miR-34c-5p suppresses proliferation and metastasis attenuating the epithelial-mesenchymal transition in colorectal cancer.
Topics: 3' Untranslated Regions; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Decitabine; DNA Methylation; Epithelial-Mesenchymal Transition; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Matrix Attachment Region Binding Proteins; MicroRNAs; Middle Aged; Prognosis; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Transcription Factors | 2018 |
Hypermethylated CD36 gene affected the progression of lung cancer.
Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzamides; CD36 Antigens; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; Disease Progression; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Neoplasm Invasiveness; Xenograft Model Antitumor Assays | 2018 |
[The Relationship of Clinicopathology of p16 in Non-small Cell Lung Cancer and 5-nitrogen impurity-2'-deoxycytidine-nitrogen Impurity on the Influence of p16 Expression in Lung Cancer A549 Cells].
Topics: A549 Cells; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Deoxycytidine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Promoter Regions, Genetic | 2018 |
Epigenetic Suppression of the T-box Subfamily 2 (
Topics: Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Multigene Family; Neoplasm Staging; T-Box Domain Proteins | 2019 |
[The Effect of Methylation Level of microRNA Promoter on the Expression of microRNAs and on the Proliferation, Migration and Invasion of Lung Cancer Cells].
Topics: A549 Cells; Azacitidine; Cell Movement; Cell Proliferation; DNA Methylation; Humans; Lung Neoplasms; MicroRNAs; Neoplasm Invasiveness; Promoter Regions, Genetic | 2019 |
Blockade of DNA methylation enhances the therapeutic effect of gefitinib in non-small cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; CpG Islands; Decitabine; DNA Methylation; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Mutation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Quinazolines | 2013 |
DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Azacitidine; DNA Methylation; DNA Probes; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Neoplasm; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Precancerous Conditions; Proportional Hazards Models; RNA, Messenger | 2013 |
Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; Enzyme Inhibitors; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HCT116 Cells; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; RNA, Small Interfering; Stomach Neoplasms; Tumor Suppressor Protein p53; Up-Regulation | 2013 |
Effect of 5-aza-2'-deoxycytidine on cell proliferation of non- small cell lung cancer cell line A549 cells and expression of the TFPI-2 gene.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Proliferation; Flow Cytometry; Glycoproteins; Humans; Lung Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
Aerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model.
Topics: Administration, Inhalation; Aerosols; Animals; Antimetabolites, Antineoplastic; Azacitidine; Benzamides; Cytidine Deaminase; DNA Methylation; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Lung Neoplasms; Male; Neoplasm Transplantation; Pyridines; Rats; Tumor Burden | 2013 |
Effect of 5- AZn-2 '-deoxycytidine on proliferation of human lung adenocarcinoma cell line A549 in vitro.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cell Shape; Decitabine; Humans; Lung Neoplasms; Malondialdehyde; Superoxide Dismutase | 2013 |
LHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancer.
Topics: Animals; Apoptosis; Azacitidine; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Humans; LIM-Homeodomain Proteins; Lung Neoplasms; Mice; Mice, Nude; Nerve Tissue Proteins; Signal Transduction; Transcription Factors; Transcription, Genetic; Tumor Suppressor Proteins; Wound Healing | 2013 |
Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA Methylation; Epigenomics; Humans; Immunotherapy; Lung Neoplasms; Programmed Cell Death 1 Receptor; Signal Transduction; Up-Regulation | 2013 |
HOXA11 hypermethylation is associated with progression of non-small cell lung cancer.
Topics: Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Decitabine; Disease Progression; DNA Methylation; Female; Homeodomain Proteins; Humans; Lung Neoplasms; Male; Middle Aged; Paraffin Embedding; Promoter Regions, Genetic; Transfection | 2013 |
Epigenetic inactivation of heparan sulfate (glucosamine) 3-O-sulfotransferase 2 in lung cancer and its role in tumorigenesis.
Topics: Adult; Azacitidine; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Knockdown Techniques; Gene Silencing; Humans; Lung Neoplasms; Male; Neoplasm Invasiveness; Phenotype; Prognosis; Promoter Regions, Genetic; Proportional Hazards Models; Sulfotransferases | 2013 |
DNA methyltransferase inhibition reverses epigenetically embedded phenotypes in lung cancer preferentially affecting polycomb target genes.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azacitidine; Binding Sites; Cell Line, Tumor; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Phenotype; Polycomb-Group Proteins | 2014 |
Demethylation of miR-9-3 and miR-193a genes suppresses proliferation and promotes apoptosis in non-small cell lung cancer cell lines.
Topics: Antibiotics, Antineoplastic; Apoptosis; Azacitidine; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Doxorubicin; Humans; Lung Neoplasms; MicroRNAs; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B; Oligonucleotides, Antisense; Promoter Regions, Genetic; Sequence Alignment; Up-Regulation | 2013 |
Promoter methylation-mediated downregulation of PRDM5 contributes to the development of lung squamous cell carcinoma.
Topics: Adult; Aged; Animals; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Female; Humans; Lung Neoplasms; Male; Mice; Middle Aged; Promoter Regions, Genetic; Transcription Factors | 2014 |
Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers.
Topics: Adenocarcinoma; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome-Wide Association Study; Humans; Lung Neoplasms; Promoter Regions, Genetic; Reproducibility of Results; Smoking | 2014 |
RASSF10 is epigenetically inactivated and induces apoptosis in lung cancer cell lines.
Topics: Apoptosis; Azacitidine; Blotting, Western; Cell Culture Techniques; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Knockdown Techniques; Humans; Lung Neoplasms; Microscopy, Fluorescence; RNA, Small Interfering; Transfection; Tumor Suppressor Proteins | 2014 |
Kaiso interacts with p120-catenin to regulate β-catenin expression at the transcriptional level.
Topics: Azacitidine; beta Catenin; Blotting, Western; Catenins; Cell Line, Tumor; CpG Islands; Decitabine; Delta Catenin; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transcription, Genetic; Up-Regulation | 2014 |
5-Aza-2'-deoxycytidine potentiates antitumour immune response induced by photodynamic therapy.
Topics: Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Lewis Lung; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Decitabine; Disease Models, Animal; Female; Flow Cytometry; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Photochemotherapy; Reverse Transcriptase Polymerase Chain Reaction | 2014 |
Secreted frizzled related protein 1 modulates taxane resistance of human lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Azacitidine; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Membrane Proteins; Mice, Inbred BALB C; Oligonucleotide Array Sequence Analysis; Sulfonamides; Taxoids; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2014 |
SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzamides; Biomarkers, Tumor; Epigenesis, Genetic; Gene Expression Profiling; Immunologic Factors; Lung Neoplasms; Male; Oligonucleotide Array Sequence Analysis; Pyridines; Rats; Rats, Nude; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Burden | 2014 |
Integrated analysis of DNA methylation and mRNA expression profiling reveals candidate genes associated with cisplatin resistance in non-small cell lung cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Profiling; GPI-Linked Proteins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; RNA, Messenger | 2014 |
Methylation of PRDM2, PRDM5 and PRDM16 genes in lung cancer cells.
Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Humans; Lung Neoplasms; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; Time Factors; Transcription Factors | 2014 |
The N-terminal transactivation domain of the glucocorticoid receptor mediates apoptosis of human small cell lung cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mifepristone; Promoter Regions, Genetic; Protein Structure, Tertiary; Receptors, Glucocorticoid; Small Cell Lung Carcinoma; Transcriptional Activation | 2014 |
Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells.
Topics: Animals; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neoplasm Transplantation; Phthalimides; Tryptophan; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2014 |
Aerosol azacytidine inhibits orthotopic lung cancers in mice through Its DNA demethylation and gene reactivation effects.
Topics: Administration, Inhalation; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Disease Models, Animal; DNA Methylation; Female; Lung Neoplasms; Male; Mice; Promoter Regions, Genetic; Transcriptional Activation; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2014 |
Identification of HERC5 and its potential role in NSCLC progression.
Topics: Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromosome Deletion; Chromosomes, Human, Pair 4; Decitabine; DNA Copy Number Variations; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Promoter Regions, Genetic; Survival Analysis | 2015 |
Promoter methylation-mediated silencing of β-catenin enhances invasiveness of non-small cell lung cancer and predicts adverse prognosis.
Topics: Aged; Azacitidine; beta Catenin; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Membrane; Decitabine; DNA Methylation; Female; Gene Silencing; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Prognosis; Promoter Regions, Genetic; Wnt Signaling Pathway | 2014 |
Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzamides; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; DNA Methylation; Drug Evaluation, Preclinical; Epigenesis, Genetic; Female; Histones; Humans; Irinotecan; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Pyridines | 2015 |
5-azacytidine enhances efficacy of multiple chemotherapy drugs in AML and lung cancer with modulation of CpG methylation.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Non-Small-Cell Lung; CpG Islands; DNA Methylation; Drug Synergism; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Tumor Cells, Cultured; U937 Cells | 2015 |
Downregulation of the microRNA-1/133a cluster enhances cancer cell migration and invasion in lung-squamous cell carcinoma via regulation of Coronin1C.
Topics: Aged; Aged, 80 and over; Azacitidine; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Microfilament Proteins; MicroRNAs; Middle Aged; Multigene Family; Neoplasm Invasiveness; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2015 |
Increased expression of 17-beta-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer.
Topics: Adult; Aged; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA Methylation; Estradiol Dehydrogenases; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Tumor Burden | 2015 |
Demethylation-mediated miR-129-5p up-regulation inhibits malignant phenotype of osteogenic osteosarcoma by targeting Homo sapiens valosin-containing protein (VCP).
Topics: Adenosine Triphosphatases; Azacitidine; Carcinogenesis; Cell Cycle Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Osteosarcoma; Signal Transduction; Valosin Containing Protein | 2015 |
Targeted inhibition of genome-wide DNA methylation analysis in epigenetically modulated phenotypes in lung cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Humans; Lung Neoplasms; Phenotype | 2015 |
Epigenetics and miRNA as predictive markers and targets for lung cancer chemotherapy.
Topics: Antibiotics, Antineoplastic; Azacitidine; Biomarkers, Tumor; Blotting, Western; Cell Line, Tumor; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Doxorubicin; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Lung Neoplasms; MicroRNAs; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction | 2015 |
TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer.
Topics: Aged; Animals; Apoptosis; Azacitidine; Biomarkers, Tumor; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Male; Membrane Proteins; Middle Aged; Multivariate Analysis; Prognosis; Rats | 2015 |
The DNA Methyltransferase DNMT1 and Tyrosine-Protein Kinase KIT Cooperatively Promote Resistance to 5-Aza-2'-deoxycytidine (Decitabine) and Midostaurin (PKC412) in Lung Cancer Cells.
Topics: Animals; Antigens, CD; Azacitidine; Cadherins; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-kit; Staurosporine | 2015 |
Silencing of miR-137 by aberrant promoter hypermethylation in surgically resected lung cancer.
Topics: Aged; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Lung Neoplasms; Male; MicroRNAs; Middle Aged; Neoplasm Staging; Prognosis; Promoter Regions, Genetic; Risk Factors; Sequence Analysis, DNA | 2015 |
Effect of DR4 promoter methylation on the TRAIL-induced apoptosis in lung squamous carcinoma cell.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Prognosis; Promoter Regions, Genetic; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand | 2015 |
Lack of ADAM2, CALR3 and SAGE1 Cancer/Testis Antigen Expression in Lung and Breast Cancer.
Topics: ADAM Proteins; Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Calreticulin; Cell Line, Tumor; Cohort Studies; Female; Fertilins; Humans; Immunohistochemistry; Lung Neoplasms; Melanoma-Specific Antigens; Membrane Glycoproteins | 2015 |
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
Topics: Animals; Azacitidine; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; Endogenous Retroviruses; Female; Humans; Immunotherapy; Interferon Type I; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; RNA, Double-Stranded | 2015 |
[5-aza-2'-deoxycytidine suppresses the growth of human lung adenocarcinoma cells in nude mouse xenograft models and its effect on methylation status and expression of TFPI-2 gene].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Proliferation; Decitabine; Disease Models, Animal; DNA Methylation; Gene Expression Regulation, Neoplastic; Glycoproteins; Heterografts; Humans; Lung Neoplasms; Mice; Mice, Nude; Random Allocation; RNA, Messenger | 2015 |
Toxicity and Pharmacokinetic Studies of Aerosolized Clinical Grade Azacitidine.
Topics: Administration, Inhalation; Administration, Intravenous; Animals; Azacitidine; Female; Humans; Leukocytes; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred ICR | 2016 |
Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation.
Topics: Animals; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; Cellular Senescence; CpG Islands; DNA Methylation; DNA-Binding Proteins; Dynamin I; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Mice; Mice, Knockout; Neoplasm Proteins; Oncogenes; Pancreatic Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras) | 2015 |
5-Aza-CdR can reverse gefitinib resistance caused by DAPK gene promoter methylation in lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Azacitidine; Blotting, Western; Cell Line, Tumor; Death-Associated Protein Kinases; DNA Methylation; Drug Resistance, Neoplasm; Flow Cytometry; Gefitinib; Humans; Lung Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; Quinazolines | 2015 |
Take two: Combining immunotherapy with epigenetic drugs to tackle cancer.
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzamides; Carcinoma, Non-Small-Cell Lung; Epigenesis, Genetic; Humans; Immunotherapy; Lung Neoplasms; Nivolumab; Pyridines | 2016 |
Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC.
Topics: 5-Methylcytosine; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Computational Biology; Down-Regulation; Epigenesis, Genetic; Humans; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Mixed Function Oxygenases; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Tumor Escape | 2016 |
PHOX2B is a suppressor of neuroblastoma metastasis.
Topics: Animals; Azacitidine; Biomarkers, Tumor; DNA Methylation; Homeodomain Proteins; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm, Residual; Neuroblastoma; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Transcription Factors | 2016 |
Pax5 Re-expression in H460 Cells Treated with the Combination of Demethylating Agent and Histone Deacetylase Inhibitor is Associated with the Enhancement of P53 Binding to Pax5 Promoter Region.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; PAX5 Transcription Factor; Promoter Regions, Genetic; Tumor Suppressor Protein p53; Vorinostat | 2017 |
Decreased expression of connective tissue growth factor in non-small cell lung cancer is associated with clinicopathological variables and can be restored by epigenetic modifiers.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Connective Tissue Growth Factor; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Middle Aged; Prognosis; Promoter Regions, Genetic; Tumor Cells, Cultured | 2016 |
Olfactomedin 1 negatively regulates NF-κB signalling and suppresses the growth and metastasis of colorectal cancer cells.
Topics: Animals; Azacitidine; Biomarkers; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Decitabine; Disease-Free Survival; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; NF-kappa B; NF-kappaB-Inducing Kinase; Prognosis; Protein Serine-Threonine Kinases; Signal Transduction | 2016 |
Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Azacitidine; Biomarkers, Tumor; Cell Proliferation; DNA Helicases; DNA Methylation; Drug Resistance, Neoplasm; Glucocorticoids; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Mice; Mice, Nude; Mutation; Nuclear Proteins; Proto-Oncogene Proteins c-myc; Transcription Factors; Tretinoin; Tumor Cells, Cultured; Vorinostat; Xenograft Model Antitumor Assays | 2017 |
Hypomethylation reduced the aggressive potential of human malignant mesothelioma cells.
Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Survival; CpG Islands; Decitabine; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant | 2016 |
Hypermethylation of ATP-binding cassette B1 (ABCB1) multidrug resistance 1 (MDR1) is associated with cisplatin resistance in the A549 lung adenocarcinoma cell line.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Azacitidine; Cell Survival; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; RNA, Messenger | 2016 |
Aberrant promoter methylation of hOGG1 may be associated with increased risk of non-small cell lung cancer.
Topics: A549 Cells; Aged; Asian People; Azacitidine; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Chi-Square Distribution; China; Decitabine; DNA Glycosylases; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Humans; Logistic Models; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Assessment; Risk Factors | 2017 |
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Azacitidine; Butyric Acid; Cell Proliferation; Chromones; Claudin-2; Down-Regulation; Epigenesis, Genetic; Humans; Hydroxamic Acids; Lung Neoplasms; MicroRNAs; Morpholines; Nitriles; RNA, Messenger; Signal Transduction; Sulfones | 2017 |
A histone deacetylase inhibitor enhances expression of genes inhibiting Wnt pathway and augments activity of DNA demethylation reagent against nonsmall-cell lung cancer.
Topics: Acetylation; Amides; Animals; Apoptosis; Azacitidine; Biomarkers, Tumor; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Proliferation; Decitabine; DNA Methylation; Drug Synergism; Drug Therapy, Combination; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Immunoenzyme Techniques; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2017 |
Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues.
Topics: Azacitidine; Binding Sites; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms | 2008 |
HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells.
Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Lung Neoplasms; Models, Theoretical; Tumor Cells, Cultured | 2008 |
AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma.
Topics: Acetylation; Adenocarcinoma; Adipokines; Adult; Aged; Aged, 80 and over; Autoantibodies; Azacitidine; Biomarkers, Tumor; Carrier Proteins; Case-Control Studies; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycoproteins; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Lung Neoplasms; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Cells, Cultured | 2008 |
The property of methylated APC gene promotor and its influence on lung cancer cell line.
Topics: Adenomatous Polyposis Coli Protein; Azacitidine; Binding Sites; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Gene Silencing; Genes, APC; Humans; Lung Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic | 2009 |
Aberrant methylation of ADAMTS1 in non-small cell lung cancer.
Topics: ADAM Proteins; ADAMTS1 Protein; Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chi-Square Distribution; Decitabine; DNA Methylation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
The comet assay: a sensitive method for detecting DNA damage in individual cells.
Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Comet Assay; Decitabine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Ethidium; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Microscopy, Fluorescence; Mutagenicity Tests; Sensitivity and Specificity; Small Cell Lung Carcinoma | 2009 |
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.
Topics: Animals; Azacitidine; Cell Line; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Diethylnitrosamine; DNA Methylation; Female; Immunohistochemistry; Lung; Lung Neoplasms; Male; Methylcholanthrene; Microdissection; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Gene Knockdown Techniques; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Lung Neoplasms | 2009 |
Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications.
Topics: Acetylation; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Chromatin Assembly and Disassembly; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; Phenylbutyrates; Receptors, Prostaglandin E; RNA, Messenger; Tumor Cells, Cultured; Vorinostat | 2009 |
Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.
Topics: Azacitidine; Cell Cycle Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Lung Neoplasms; Neoplasms, Squamous Cell; Peroxisome Proliferator-Activated Receptors; Pioglitazone; Thiazolidinediones; Transcription, Genetic; Tretinoin | 2009 |
IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HeLa Cells; HT29 Cells; Humans; Hydroxamic Acids; Insulin-Like Growth Factor Binding Protein 3; Kaplan-Meier Estimate; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tumor Cells, Cultured | 2010 |
SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.
Topics: Azacitidine; beta Catenin; beta-Transducin Repeat-Containing Proteins; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Movement; Decitabine; Disease Progression; DNA Methylation; Gene Knockdown Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Nerve Tissue Proteins; Oncogene Protein v-akt; Prognosis; Promoter Regions, Genetic; Receptors, Immunologic; RNA, Messenger; Roundabout Proteins | 2010 |
Induction of apoptosis of non-small cell lung cancer by a methylated oligonucleotide targeting survivin gene.
Topics: Apoptosis; Azacitidine; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Modification Methylases; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Microtubule-Associated Proteins; Oligonucleotides; Reverse Transcriptase Polymerase Chain Reaction; Survivin; Transfection | 2010 |
Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma.
Topics: Acyltransferases; Azacitidine; Calcium-Binding Proteins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Membrane Proteins; Neoplasm Proteins; RNA Interference; RNA, Messenger; Time Factors; Transcriptional Activation | 2010 |
Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells.
Topics: Adenocarcinoma; Animals; Azacitidine; Cell Line, Tumor; Decitabine; Early Growth Response Protein 1; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; Vascular Endothelial Growth Factor A | 2010 |
[The relationship between the TSLC1 silencing and DNA methylation in human lung cancer cells].
Topics: Azacitidine; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Silencing; Humans; Immunoglobulins; Lung Neoplasms; Promoter Regions, Genetic; Tumor Suppressor Proteins | 2010 |
Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression.
Topics: Apoptosis; Azacitidine; Benzamides; Cell Cycle; Cell Line, Tumor; Cell Survival; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Indoles; Interferons; Lung Neoplasms; Panobinostat; Phosphorylation; Pyrimidines; Small Cell Lung Carcinoma | 2010 |
Intratracheally administered 5-azacytidine is effective against orthotopic human lung cancer xenograft models and devoid of important systemic toxicity.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; DNA Methylation; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Injections; Injections, Intravenous; Lung Neoplasms; Male; Maximum Tolerated Dose; Mice; Mice, Inbred ICR; Mice, Nude; Trachea; Xenograft Model Antitumor Assays | 2010 |
Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
Topics: Animals; Azacitidine; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Decitabine; Diethylnitrosamine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Enzyme Inhibitors; Female; Gene Silencing; Immunoglobulins; Lung Neoplasms; Male; Methylcholanthrene; Rats; Rats, Wistar; Tissue Inhibitor of Metalloproteinase-3; Up-Regulation | 2011 |
Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Benzamides; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Histone Deacetylase Inhibitors; Humans; Lung Neoplasms; Male; Pyridines; Rats; Signal Transduction; Xenograft Model Antitumor Assays | 2011 |
Epigenetic mechanisms for silencing glutathione S-transferase m2 expression by hypermethylated specificity protein 1 binding in lung cancer.
Topics: Aged; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Glutathione Transferase; Humans; Lung Neoplasms; Male; Sp1 Transcription Factor | 2011 |
Reactivation of Syk gene by AZA suppresses metastasis but not proliferation of breast cancer cells.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mice; Mice, Nude; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Syk Kinase | 2012 |
Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatin Immunoprecipitation; Cohort Studies; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Lung Neoplasms; Male; Matrix Attachment Region Binding Proteins; Middle Aged; Neoplasm Staging; Prognosis; Tissue Array Analysis | 2011 |
Aberrant methylation of N-methyl-D-aspartate receptor type 2B (NMDAR2B) in non-small cell carcinoma.
Topics: Adult; Aged; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Neoplasm Staging; Pneumonectomy; Prognosis; Proportional Hazards Models; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; RNA, Neoplasm; Sampling Studies | 2011 |
Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL.
Topics: Azacitidine; Blotting, Western; Caspase 8; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Enzyme Inhibitors; Fluorescent Antibody Technique; Histone Deacetylases; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Membrane Potential, Mitochondrial; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Small Cell Lung Carcinoma; Survivin; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Valproic Acid | 2011 |
[Reversal effect of 5-Aza-dc on cisplatin-resistance in human NSCLC cells in vitro].
Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; MutL Protein Homolog 1; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger | 2011 |
Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells.
Topics: Apoptosis; Azacitidine; Base Sequence; Caspase 3; Cell Line, Tumor; CpG Islands; DNA Methylation; Enzyme Inhibitors; Glucocorticoids; HEK293 Cells; Humans; Lung Neoplasms; Molecular Sequence Data; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Receptors, Glucocorticoid; Small Cell Lung Carcinoma; Transgenes | 2011 |
5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Lung Neoplasms; Osteosarcoma; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-mdm2; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130 | 2012 |
AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer.
Topics: Aged; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytokines; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Male; Middle Aged; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Signal Transduction; Tumor Suppressor Proteins | 2012 |
Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses.
Topics: Azacitidine; Cell Line, Tumor; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Interferon Regulatory Factor-7; Interferon Regulatory Factors; Interferons; Lung Neoplasms; Oncolytic Viruses; Poly I-C; Promoter Regions, Genetic; Sequence Analysis, DNA; Signal Transduction; Vesiculovirus | 2011 |
DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung.
Topics: Aged; Azacitidine; Cell Line; Cytochrome P-450 CYP1A1; Decitabine; DNA Methylation; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Male; Middle Aged; RNA, Messenger; Smoking | 2012 |
Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers.
Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Profiling; Gene Silencing; Humans; Hydroxamic Acids; Lung; Lung Neoplasms; Male; MicroRNAs; Middle Aged; Molecular Targeted Therapy; Oligonucleotide Array Sequence Analysis | 2012 |
Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer.
Topics: Azacitidine; Carcinoma, Non-Small-Cell Lung; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epithelial Cells; Lung; Lung Neoplasms; Phenotype; Promoter Regions, Genetic; Smoke; Smoking; Wnt Proteins | 2012 |
TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Animals; Antigens, Neoplasm; Azacitidine; Base Sequence; Cell Adhesion Molecules; Cell Line, Tumor; Decitabine; Disease Models, Animal; Epigenesis, Genetic; Female; Gene Expression; Gene Expression Regulation; Gene Silencing; Histocytochemistry; Humans; Immunohistochemistry; Lung Neoplasms; Male; Mice; Middle Aged; Models, Biological; Molecular Sequence Data; Receptor, IGF Type 1; Signal Transduction | 2012 |
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.
Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine | 2012 |
5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.
Topics: Apoptosis; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Core Binding Factor Alpha 3 Subunit; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; DNA Methyltransferase 3A; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Lung Neoplasms; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2012 |
CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer.
Topics: Azacitidine; CDX2 Transcription Factor; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Homeodomain Proteins; Humans; Lung Neoplasms; Promoter Regions, Genetic; Wnt Signaling Pathway | 2012 |
Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.
Topics: Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genetic Predisposition to Disease; Genotype; Humans; Lung Neoplasms; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Receptors, Nicotinic | 2013 |
ANKRD18A as a novel epigenetic regulation gene in lung cancer.
Topics: Ankyrin Repeat; Azacitidine; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Promoter Regions, Genetic | 2012 |
[Effects of 5-Aza-2-deoxycytidine on DNA methylation of anti-oncogenes in non-small cell lung cancer cells].
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Lymphatic Metastasis; Male; Membrane Proteins; Neoplasm Staging; RNA, Messenger; Tumor Suppressor Proteins | 2012 |
Abnormal hypermethylation and clinicopathological significance of Axin gene in lung cancer.
Topics: Adenocarcinoma; Axin Protein; Azacitidine; Base Sequence; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Molecular Sequence Data; Neoplasm Staging; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
IRF-8 controls melanoma progression by regulating the cross talk between cancer and immune cells within the tumor microenvironment.
Topics: Animals; Azacitidine; CD4 Lymphocyte Count; Chemokines; Decitabine; Dendritic Cells; Disease Progression; Humans; Interferon Regulatory Factors; Interleukin-17; Interleukins; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor Cross-Talk; Receptors, Chemokine; Spleen; T-Lymphocytes; Tumor Microenvironment; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor B; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Azacitidine; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 8; CpG Islands; Decitabine; DNA Modification Methylases; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Loss of Heterozygosity; Lung Neoplasms; Nerve Tissue Proteins; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Antineoplastic action of 5-aza-2'-deoxycytidine and phenylbutyrate on human lung carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; DNA, Neoplasm; Drug Synergism; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Lung Neoplasms; Phenylbutyrates; Tumor Cells, Cultured | 2002 |
Induction of TRAG-3 expression in A549 lung adenocarcinoma cell line by 5-aza-2' deoxyazacytidine.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lung Neoplasms; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2002 |
Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Alleles; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; RNA, Messenger; Sputum | 2003 |
Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 3; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Loss of Heterozygosity; Lung Neoplasms; Male; Membrane Glycoproteins; Middle Aged; Neoplasm Proteins; Promoter Regions, Genetic; Semaphorins; Tumor Cells, Cultured | 2003 |
The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.
Topics: Adenocarcinoma; Animals; Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; Enzyme Inhibitors; Gene Expression Profiling; Genes, Tumor Suppressor; Glypicans; Humans; Hydroxamic Acids; Lung Neoplasms; Membrane Proteins; Mice; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Respiratory Mucosa; Smoking; Tumor Suppressor Proteins | 2003 |
Epigenetic inactivation of laminin-5-encoding genes in lung cancers.
Topics: Azacitidine; Carcinoid Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Adhesion Molecules; Cell Line, Tumor; CpG Islands; Decitabine; DNA; DNA Methylation; Humans; Kalinin; Laminin; Lung Neoplasms; Lymphocytes; Methylation; Models, Genetic; Mouth Mucosa; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sulfites; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.
Topics: Azacitidine; Breast Neoplasms; Carcinoma, Squamous Cell; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Gene Expression; Humans; Lung Neoplasms; Microsatellite Repeats; PAX5 Transcription Factor; Promoter Regions, Genetic; Transcription Factors; Tumor Cells, Cultured | 2003 |
Epigenetic down-regulation of death-associated protein kinase in lung cancers.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cells, Cultured; CpG Islands; Death-Associated Protein Kinases; Decitabine; DNA; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Exons; Gene Silencing; Genetic Techniques; Humans; Lung Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Sulfites; Time Factors; Tumor Cells, Cultured | 2003 |
Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cyclin D2; Cyclins; DNA Methylation; Female; Humans; Lung Neoplasms; Middle Aged; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured | 2003 |
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.
Topics: Alleles; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Female; Gene Dosage; Histone Deacetylase Inhibitors; Histones; Lung Neoplasms; Male; Mice; Mice, Inbred A; Phenylbutyrates | 2003 |
Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines.
Topics: Adenocarcinoma; Animals; Azacitidine; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Fibroblasts; Gene Silencing; Histiocytoma, Benign Fibrous; Lung Neoplasms; Neoplasms; Osteosarcoma; Promoter Regions, Genetic; Rats; RNA, Messenger; Sulfites; TATA Box; Tumor Cells, Cultured | 2004 |
Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cadherins; Cell Line, Tumor; Decitabine; DNA; Docetaxel; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Male; Prostatic Neoplasms; Proteins; Serpins; Taxoids; Time Factors | 2004 |
Gamma-catenin expression is reduced or absent in a subset of human non-small cell lung cancers, and its re-expression inhibits cell growth.
Topics: Azacitidine; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line, Tumor; Cytoskeletal Proteins; Decitabine; Desmoplakins; DNA Modification Methylases; gamma Catenin; Humans; Hydroxamic Acids; Lung Neoplasms; Neoplasm Proteins; Trans-Activators | 2004 |
5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Caspase 9; Caspases; Cell Line, Tumor; Decitabine; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Tumor Suppressor Protein p53 | 2004 |
Downregulation of connexin 26 in human lung cancer is related to promoter methylation.
Topics: Actins; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Northern; Blotting, Southern; Carcinoma, Squamous Cell; Cell Line, Tumor; Connexin 26; Connexins; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Immunohistochemistry; Lung Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA | 2005 |
Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cloning, Molecular; Coloring Agents; Death-Associated Protein Kinases; Decitabine; DNA Fragmentation; DNA Methylation; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fas Ligand Protein; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lung Neoplasms; Membrane Glycoproteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Treatment Outcome; Tumor Necrosis Factor-alpha | 2004 |
Aberrant methylation of Reprimo in lung cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Decitabine; DNA Methylation; Genes, p53; Glycoproteins; Humans; Lung Neoplasms; Lymphocytes; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2005 |
Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Decitabine; Depsipeptides; DNA Primers; Esophageal Neoplasms; Glycoproteins; Humans; Lung Neoplasms | 2005 |
RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression.
Topics: Azacitidine; Cell Growth Processes; Cell Line, Tumor; Decitabine; G1 Phase; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Transfection; Tumor Suppressor Proteins | 2005 |
Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines.
Topics: Alleles; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Chromosomes, Human, Pair 1; Core Binding Factor Alpha 3 Subunit; CpG Islands; DNA Methylation; DNA, Complementary; Down-Regulation; Exons; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; In Situ Hybridization, Fluorescence; Lung Neoplasms; Polymerase Chain Reaction; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines.
Topics: Acetylation; Androstadienes; Azacitidine; Chromatin; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; Lysine; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Wortmannin | 2005 |
Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma; Carcinoma, Non-Small-Cell Lung; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulins; Lung Neoplasms; Membrane Proteins; Microfilament Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2006 |
RARbeta1': primed to fight retinoid resistance in lung carcinogenesis.
Topics: Alternative Splicing; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Protein Isoforms; Receptors, Retinoic Acid; Respiratory Mucosa; Retinoid X Receptors; Tretinoin | 2005 |
A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Bone Morphogenetic Proteins; Bronchial Neoplasms; Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; GTP-Binding Proteins; Humans; Immunoblotting; Luciferases; Lung Neoplasms; Membrane Proteins; Promoter Regions, Genetic; Protein Glutamine gamma Glutamyltransferase 2; Protein Isoforms; Proto-Oncogene Proteins c-fos; Receptors, Retinoic Acid; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Transfection; Transglutaminases; Tretinoin | 2005 |
Aberrant promoter methylation of EDNRB in lung cancer in Taiwan.
Topics: Azacitidine; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Promoter Regions, Genetic; Receptor, Endothelin B; Sequence Analysis, DNA; Taiwan | 2006 |
Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Cloning, Molecular; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Epithelial Cells; Gene Deletion; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; Histone Deacetylase Inhibitors; Homozygote; Humans; Hydroxamic Acids; Lung Neoplasms; Molecular Sequence Data; Transfection | 2006 |
Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer.
Topics: Animals; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Cell Cycle; Cell Line, Tumor; Chromosomes, Human, Pair 6; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Epigenesis, Genetic; Gene Expression Regulation; Gene Silencing; Genome; Head and Neck Neoplasms; Humans; Immunohistochemistry; Loss of Heterozygosity; Luciferases; Lung; Lung Neoplasms; Mice; Mice, Nude; Models, Genetic; Neoplasm Transplantation; Open Reading Frames; Plasmids; Promoter Regions, Genetic; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Sulfites; Time Factors; Transfection | 2006 |
De novo induction of a cancer/testis antigen by 5-aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model.
Topics: Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Chromatin; CpG Islands; Decitabine; DNA Methylation; Gene Expression Profiling; Humans; Immunotherapy, Adoptive; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous; Tumor Cells, Cultured | 2006 |
Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer.
Topics: Acetylation; Azacitidine; Blotting, Northern; Blotting, Southern; Carcinoma, Non-Small-Cell Lung; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Methyl-CpG-Binding Protein 2; Mutagenesis; Promoter Regions, Genetic; Sequence Analysis, DNA; Upstream Stimulatory Factors | 2006 |
Aberrant methylation of RASGRF2 and RASSF1A in human non-small cell lung cancer.
Topics: Aged; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cells, Cultured; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung; Lung Neoplasms; Male; Neoplasm Staging; ras Guanine Nucleotide Exchange Factors; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Proteins | 2006 |
Gene promoter hypermethylation in mouse lung tumors.
Topics: Animals; Azacitidine; Biomarkers, Tumor; Cadherins; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Estrogen Receptor alpha; Gene Silencing; Genes, Neoplasm; Humans; Lung Neoplasms; Mice; Promoter Regions, Genetic; Receptors, Progesterone; TCF Transcription Factors; Transcription Factor 7-Like 1 Protein | 2006 |
Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing.
Topics: Animals; Azacitidine; Blotting, Western; Carcinoma; Cell Line; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epigenesis, Genetic; Fibroblasts; Gene Silencing; Histones; Humans; Kinetics; Lung Neoplasms; Lysine; Methyltransferases; Mice; Nickel; Trace Elements; Transgenes | 2006 |
Epigenetic inactivation of Betaig-h3 gene in human cancer cells.
Topics: Azacitidine; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Luciferases; Lung Neoplasms; Male; Neoplasms; Promoter Regions, Genetic; Prostatic Neoplasms; Transforming Growth Factor beta | 2006 |
Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity.
Topics: Acid Anhydride Hydrolases; Animals; Apoptosis; Azacitidine; Carcinoma, Non-Small-Cell Lung; Caspases; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Proteins; Oxidoreductases; Promoter Regions, Genetic; Transgenes; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Proteins; WW Domain-Containing Oxidoreductase | 2007 |
Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.
Topics: Acetylation; Adenocarcinoma; Azacitidine; Biomarkers, Tumor; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chromatin Immunoprecipitation; Colony-Forming Units Assay; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2007 |
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Cathepsin K; Cathepsins; Colonic Neoplasms; CpG Islands; Cyclin A; Cyclin A1; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Profiling; Humans; Lung Neoplasms; Male; Middle Aged; MSX1 Transcription Factor; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Transcription Factors; Tumor Cells, Cultured | 2006 |
Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; CpG Islands; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Male; Middle Aged; Promoter Regions, Genetic; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 2007 |
Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer.
Topics: Aged; Amino Acid Motifs; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Membrane Glycoproteins; Mutation; Neoplasm Invasiveness; Promoter Regions, Genetic; ras Proteins | 2007 |
Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer.
Topics: Adenocarcinoma; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Epithelial Cells; Humans; Immunohistochemistry; Insulin-Like Growth Factor Binding Proteins; Lung; Lung Neoplasms; Microarray Analysis; Neoplasm Staging; Transfection; Tumor Suppressor Proteins | 2007 |
Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter.
Topics: Azacitidine; Cells, Cultured; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Erythroblastic, Acute; Lung Neoplasms; Promoter Regions, Genetic; Receptor Protein-Tyrosine Kinases; Transcription, Genetic; Transgenes | 2007 |
Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers.
Topics: Aged; Azacitidine; Base Sequence; Blotting, Western; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Lung Neoplasms; Male; Middle Aged; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Smoking; Transfection; Tumor Suppressor Protein p53 | 2007 |
[Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines].
Topics: Adenocarcinoma; Adenomatous Polyposis Coli Protein; Azacitidine; Carcinoma, Large Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Genes, APC; Humans; Lung Neoplasms; Promoter Regions, Genetic; Small Cell Lung Carcinoma; Transcription, Genetic | 2007 |
Epigenetic regulation of RhoB loss of expression in lung cancer.
Topics: Azacitidine; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Immunoblotting; Lung Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; rhoB GTP-Binding Protein; Sulfites; Tandem Repeat Sequences | 2007 |
Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type beta-catenin nuclear accumulation in lung tumorigenesis.
Topics: Active Transport, Cell Nucleus; Axin Protein; Azacitidine; beta Catenin; beta-Transducin Repeat-Containing Proteins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Nucleus; Cytoskeletal Proteins; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Silencing; Humans; Hydroxamic Acids; Lung Neoplasms; Prognosis; Promoter Regions, Genetic; Tumor Suppressor Protein p53; Vorinostat | 2008 |
Epigenetic remodeling during arsenical-induced malignant transformation.
Topics: Acetylation; Arsenicals; Azacitidine; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Decitabine; Environmental Exposure; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Teratogens; Urinary Bladder Neoplasms; Urothelium | 2008 |
Sequential combination of pyrazofurin and 5-azacytidine in patients with acute myelocytic leukemia and carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Amides; Azacitidine; Carcinoma; Carcinoma, Small Cell; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Lung Neoplasms; Male; Middle Aged; Pyrazoles; Ribonucleosides; Ribose | 1981 |
The tumorigenicity of 5-azacytidine in the male Fischer rat.
Topics: Animals; Azacitidine; DNA; Kidney Neoplasms; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphatic Diseases; Male; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Skin Neoplasms; Testicular Neoplasms | 1984 |
CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2'deoxycytidine.
Topics: Azacitidine; Base Sequence; Carrier Proteins; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Protein Kinase Inhibitors; Tumor Cells, Cultured | 1995 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Evaluation of the antineoplastic activity of adozelesin alone and in combination with 5-aza-2'-deoxycytidine and cytosine arabinoside on DLD-1 human colon carcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzofurans; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Cyclohexanecarboxylic Acids; Cyclohexenes; Cytarabine; Decitabine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Duocarmycins; Humans; Indoles; Lung Neoplasms; Time Factors; Tumor Cells, Cultured | 1993 |
Frequent aberrant methylation of p16INK4a in primary rat lung tumors.
Topics: Amino Acid Sequence; Animals; Azacitidine; Base Sequence; Carrier Proteins; Cloning, Molecular; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Disease Models, Animal; DNA Methylation; Exons; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Molecular Sequence Data; Proteins; Rats; Rats, Inbred F344; Sequence Analysis, DNA; Sequence Deletion; Sequence Homology, Amino Acid; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF | 1997 |
Counter-selection for over-expressed human CD44s in primary tumors versus lung metastases in a mouse fibrosarcoma model.
Topics: 3T3 Cells; Animals; Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Decitabine; Fibrosarcoma; Genes, ras; Humans; Hyaluronan Receptors; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Oncogene Proteins v-sis; Oncogenes; Retroviridae Proteins, Oncogenic; Transfection | 1997 |
Differential expression of MHC class II genes in lung tumour cell lines.
Topics: Actins; Adenocarcinoma; Antibodies, Monoclonal; Azacitidine; Blotting, Northern; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Decitabine; Densitometry; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression; Genes, MHC Class II; Genes, myc; HLA-DP Antigens; HLA-DQ Antigens; HLA-DR Antigens; Humans; Interferon-gamma; Lung Neoplasms; Proto-Oncogene Mas; RNA, Messenger; Tumor Cells, Cultured | 1998 |
5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model.
Topics: Animals; Anticarcinogenic Agents; Azacitidine; Carcinogens; Decitabine; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mice, Inbred C3H; Nitrosamines | 1999 |
Hypermethylation of the p16 (Ink4a) promoter in B6C3F1 mouse primary lung adenocarcinomas and mouse lung cell lines.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azacitidine; Carrier Proteins; Cell Division; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression; Genes, Tumor Suppressor; Immunohistochemistry; Loss of Heterozygosity; Lung Neoplasms; Mice; Mice, Inbred A; Mice, Inbred C3H; Mice, Inbred C57BL; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2000 |
Induction of MAGE-3 expression in lung and esophageal cancer cells.
Topics: Adenocarcinoma; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antigens, Neoplasm; Azacitidine; Carcinoma, Non-Small-Cell Lung; Decitabine; Depsipeptides; DNA Modification Methylases; Enzyme Inhibitors; Esophageal Neoplasms; Histone Deacetylase Inhibitors; Humans; Immunohistochemistry; Lung Neoplasms; Melanoma; Neoplasm Proteins; Peptides, Cyclic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2001 |
DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors.
Topics: Acetylation; Apoptosis; Azacitidine; Decitabine; DNA Modification Methylases; Drug Synergism; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; Oligopeptides; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.
Topics: Acid Anhydride Hydrolases; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Blotting, Northern; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Loss of Heterozygosity; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Protein Biosynthesis; Proteins; RNA, Messenger | 2001 |
Demethylation by 5-aza-2'-deoxycytidine (5-azadC) of p16INK4A gene results in downregulation of vascular endothelial growth factor expression in human lung cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Division; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Growth Factors; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Dominant; Genes, p16; Humans; Interleukin-8; Kinetics; Lung Neoplasms; Lymphokines; Promoter Regions, Genetic; Protein Isoforms; RNA, Neoplasm; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Diminished expression of S100A2, a putative tumor suppressor, at early stage of human lung carcinogenesis.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Biomarkers, Tumor; Bronchi; Carcinoma, Non-Small-Cell Lung; Cell Line, Transformed; Cell Transformation, Neoplastic; Chemotactic Factors; Decitabine; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Staging; Oligonucleotide Array Sequence Analysis; Rats; RNA, Neoplasm; S100 Proteins; Transplantation, Heterologous; Tumor Cells, Cultured | 2001 |
Potential of 5-aza-2'-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Decitabine; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; Female; Humans; Lung Neoplasms; Male; Middle Aged | 2001 |
Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells.
Topics: Azacitidine; Blotting, Southern; Blotting, Western; Cell Cycle Proteins; Cell Survival; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p19; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Lung Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured | 2001 |
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Northern; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cells, Cultured; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Phosphoric Monoester Hydrolases; Promoter Regions, Genetic; PTEN Phosphohydrolase; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.
Topics: Animals; Azacitidine; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Drosophila melanogaster; Drosophila Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Kidney Neoplasms; Loss of Heterozygosity; Lung Neoplasms; Mutation, Missense; Nerve Tissue Proteins; Promoter Regions, Genetic; Receptors, Immunologic; Roundabout Proteins; Sequence Homology, Nucleic Acid; Tumor Cells, Cultured | 2002 |
Diffuse pulmonary malignant mesothelioma: response to doxorubicin and 5-azacytidine.
Topics: Azacitidine; Doxorubicin; Drug Therapy, Combination; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Mesothelioma; Middle Aged; Remission, Spontaneous | 1978 |
Quantitative DNA alterations during 5-azacytidine-induced differential modulation of benzo(a)pyrene carcinogenesis in hamster bronchi.
Topics: Animals; Azacitidine; Benzo(a)pyrene; Bronchi; Cricetinae; DNA; DNA, Neoplasm; Drug Implants; Lung Neoplasms; Mesocricetus; Ploidies | 1990 |
Diaplacental carcinogenic effects of 5-azacytidine in NMRI-mice.
Topics: Animals; Azacitidine; Fetus; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma, Experimental; Soft Tissue Neoplasms | 1985 |
Effect of 5-azacytidine on DNA methylation and the malignant properties of B16 melanoma cells.
Topics: Animals; Azacitidine; Deoxycytidine; DNA, Neoplasm; Female; Lung Neoplasms; Melanoma; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis | 1985 |
Enhanced experimental metastatic capacity of a human tumor line following treatment with 5-azacytidine.
Topics: Animals; Azacitidine; Cytotoxicity, Immunologic; DNA, Neoplasm; Humans; Killer Cells, Natural; Lung Neoplasms; Melanoma; Methylation; Mice; Neoplasm Metastasis; Neoplasm Transplantation | 1986 |
Metastatic phenotype of human prostate tumor cells in athymic nude mice: alteration by exposure to ethyl methanesulfonate and "reversion" by 5-azacytidine.
Topics: Animals; Azacitidine; Cell Line; Ethyl Methanesulfonate; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Phenotype; Prostatic Neoplasms | 1986 |
Fetal hemoglobin gene activation in a phase II study of 5,6-dihydro-5-azacytidine for bronchogenic carcinoma.
Topics: Adult; Antibodies, Antinuclear; Azacitidine; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Fetal Hemoglobin; Gene Expression Regulation; Globins; Heart Diseases; Humans; Lung Neoplasms; Neoplasm Proteins; Pain; Transcriptional Activation | 1987 |
Phase II study of 5,6-dihydro-5-azacytidine in extensive, untreated non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged | 1987 |
5-Azacytidine carcinogenesis in BALB/c mice.
Topics: Animals; Azacitidine; Carcinogens; Female; Lung Neoplasms; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Skin Neoplasms | 1987 |
Treatment of human cell lines with 5-azacytidine may result in profound alterations in clonogenicity and growth rate.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Humans; Lung Neoplasms; Lymphoma; Multiple Myeloma | 1985 |
Modulatory effects of 5-azacytidine, phorbol ester, and retinoic acid on the malignant phenotype of human lung cancer cells.
Topics: Animals; Azacitidine; Carcinoma, Small Cell; Cell Line; Clone Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitosis; Neoplasm Transplantation; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
New drugs on the horizon in bronchogenic carcinoma.
Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Bleomycin; Carcinoma, Bronchogenic; Carmustine; Cyclic P-Oxides; Cyclophosphamide; Dimethylamines; Doxorubicin; Ethylamines; Evaluation Studies as Topic; Humans; Ketones; Lung Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Organophosphorus Compounds; Oxazines; Piperazines; Platinum; Triazines | 1972 |
Bronchogenic carcinoma: new drugs available for study.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Bronchogenic; Chromomycins; Cyclic P-Oxides; Cyclophosphamide; Half-Life; Humans; Kinetics; Lung Neoplasms; Organometallic Compounds; Organophosphorus Compounds; Oxazines; Platinum | 1973 |