azacitidine has been researched along with Cancer of Kidney in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.64) | 18.7374 |
| 1990's | 3 (5.45) | 18.2507 |
| 2000's | 22 (40.00) | 29.6817 |
| 2010's | 26 (47.27) | 24.3611 |
| 2020's | 2 (3.64) | 2.80 |
| Authors | Studies |
|---|---|
| Kiyokawa, N; Nakasato, K; Okita, H; Ueno-Yokohata, H | 1 |
| Ma, Z; Wang, W; Zuo, Y | 1 |
| Li, X; Yu, Q | 1 |
| Carew, JS; Espitia, C; Jones, TM; Nawrocki, ST; Wang, W | 1 |
| Chen, X; Huo, Y; Li, Y; Sun, J; Wang, T; Wang, W; Wu, J; Xi, W; Yang, A; Zheng, G | 1 |
| Ellinger, J; Müller, SC; Schiffgen, M; Schmidt, DH; von Rücker, A | 1 |
| Carter, JA; Górecki, DC; Hafizi, S; Ljungberg, B; Mein, CA | 1 |
| Dong, D; Lu, D; Ma, WJ; Tian, XJ; Wen, JX; Zhang, J; Zhou, Y | 1 |
| Christensen, BC; David, JM; Lakshmikuttyamma, A; Owens, TA; Petrelli, NJ; Rajasekaran, AK; Selvakumar, P | 1 |
| Deng, Z; Lin, J; Matsuda, K; Miki, T; Nakamura, Y; Shuin, T; Tanikawa, C | 1 |
| Chen, G; Fan, Y; Jin, J; Li, L; Liu, Q; Tao, Q; Wang, L; Wang, Z; Xu, B; Ying, J; Zhang, L; Zhang, Q | 1 |
| Mizokami, A; Nakamoto, M; Nakamura, R; Namiki, M; Ooi, A; Oyama, T; Tajiri, R | 1 |
| Arichi, N; Chang, I; Dahiya, R; Deng, G; Fukuhara, S; Hiraki, M; Hirata, H; Majid, S; Mitsui, Y; Saini, S; Shahryari, V; Shiina, H; Tanaka, Y; Yamamura, S; Yasumoto, H | 1 |
| He, C; Jiang, H; Xu, R; Zhao, X; Zhong, Z | 1 |
| Han, T; Liu, Y; Shang, D; Xu, X | 1 |
| Cao, C; Chen, L; Chen, P; Tan, W; Yi, F; Zhang, X; Zhu, X | 1 |
| Du, Z; Huang, S; Huang, X; Jin, J; Li, L; Tao, Q; Zhang, Q | 1 |
| Mahalingaiah, PK; Ponnusamy, L; Singh, KP | 1 |
| Balsamo, T; Copetti, M; Costantini, M; De Salvo, L; Fabrizio, FP; Fazio, VM; Flammia, GP; Fontana, A; Gallucci, M; Graziano, P; Kok, K; la Torre, A; Muscarella, LA; Pantalone, A; Papalia, R; Paranita, F; Parente, P; Picardo, F; Poeta, L; Pompeo, V; Sentinelli, S; Simone, G; Sparaneo, A; Trombetta, D | 1 |
| Ahmad, AE; Dahiya, AV; Dahiya, R; Dar, AA; Hirata, H; Kawakami, K; Khatri, G; Majid, S; Saini, S; Shahryari, V; Tanaka, Y | 1 |
| Dahiya, R; Hinoda, Y; Hirata, H; Ishii, N; Kawakami, K; Kawamoto, K; Kikuno, N; Majid, S; Nakajima, K; Saini, S; Ueno, K; Yamamura, S | 1 |
| Iwata, H; Miyazawa, M; Sato, H; Takano, Y; Ueno, K; Virgona, N; Yano, T; Yano, Y | 1 |
| Chen, Y; Dahiya, R; Deng, G; Hinoda, Y; Hirata, H; Ishii, N; Kawamoto, K; Khatri, G; Kikuno, N; Majid, S; Nakajima, K; Saini, S; Ueno, K; Yamamura, S; Zaman, MS | 1 |
| Costa, VL; Duarte-Pereira, S; Henrique, R; Jerónimo, C; Lobo, F; Oliveira, J; Paiva, F; Patrício, P; Ramalho-Carvalho, J; Ribeiro, FR | 1 |
| Alcazar, O; Hu, Z; Lindner, D; Negrotto, S; Ng, KP; Rini, B; Saunthararajah, Y; Triozzi, P | 1 |
| Han, T; Liu, Y; Shang, D; Tian, Y; Xu, X | 1 |
| Daaka, Y; Gersey, Z; Kim, WJ | 1 |
| Colon-Otero, G; Cooper, SJ; Copland, JA; Grebe, SK; Kang, KH; Marlow, LA; Menefee, ME; Perez, EA; Tun, HW; von Roemeling, CA | 1 |
| Han, T; Shang, D; Tian, Y; Xu, X | 1 |
| Gallacher, J; Kalogerou, M; Sampson, JR; Shen, MH; Yang, J | 1 |
| Altomonte, M; Cattarossi, I; Colizzi, F; Coral, S; Engelsberg, A; Jager, E; Maio, M; Maraskovsky, E; Seliger, B; Sigalotti, L | 1 |
| Dahiya, R; Deguchi, M; Igawa, M; Kaneuchi, M; Nakajima, K; Shiina, H | 1 |
| Alleman, WG; Aprelikova, ON; Chandramouli, GV; Linehan, WM; Mendoza, A; Rodgers, C; Rogers, C; Sopko, NA; Tabios, RL; Torres-Cabala, C; Vasselli, JR | 1 |
| Jang, T; Lee, C; Liu, VC; Park, I; Rubenstein, JN; Zhang, Q | 1 |
| Breault, JE; Carroll, PR; Dahiya, R; Deguchi, M; Enokida, H; Igawa, M; Kane, CJ; Nakagawa, M; Ribeiro-Filho, LA; Shiina, H; Terashima, M; Urakami, S | 1 |
| Biesová, Z; Jakubicková, L; Kettmann, R; Pastorek, J; Pastoreková, S | 1 |
| Daniel, PT; Dörken, B; Gillissen, B; Janz, M; Jung, K; Loening, S; Radetzki, S; Siebert, R; Stephan, C; Sturm, I | 1 |
| Chun, K; Costa, R; Haghighi, F; McMinn, J; Minden, M; Tycko, B; White, S; Yuan, E | 1 |
| Al-Saleem, T; Cairns, P; Dulaimi, E; Hoffman, AM; Ibanez de Caceres, I; Uzzo, RG | 1 |
| Bae, SI; Beaulieu, N; Borden, EC; Cherkassky, L; Leaman, DW; Lindner, D; MacLeod, AR; Reu, FJ | 1 |
| Dressman, HK; Gollob, JA; Issa, JP; Jelinek, J; Moran, K; Peterson, BL; Richmond, T; Sciambi, CJ; Thoreson, M | 1 |
| Bates, SE; To, KK; Zhan, Z | 1 |
| Christoph, F; Kempkensteffen, C; Köllermann, J; Krause, H; Miller, K; Schostak, M; Schrader, M; Weikert, S | 1 |
| Baker, JA; Brown, KW; Chilukamarri, L; Dallosso, AR; Greenhough, A; Hancock, AL; Huang, TH; Malik, K; Malik, S; Royer-Pokora, B; Zabkiewicz, J | 1 |
| Dahiya, R; Hirata, H; Kawamoto, K; Kikuno, N; Nakagawa, M; Tanaka, Y | 1 |
| Carr, BI; Reilly, JG; Riggs, A; Smith, SS; Winberg, C | 1 |
| Bander, NH; Broadus, AE; Holt, EH; Philbrick, WM; Vasavada, RC | 1 |
| Chung, WY; Feng, L; Hensle, T; Tycko, B; Yuan, L | 1 |
| Bachman, KE; Baylin, SB; Cavenee, WK; Corn, PG; Costello, JF; Graff, JR; Herman, JG; Merlo, A | 1 |
| Cho, M; Grabmaier, K; Hiasa, Y; Hirao, Y; Kitahori, Y; Nakagawa, Y; Ohnishi, T; Ooesterwijk, E; Uemura, H; Yoshikawa, K | 1 |
| Kajiwara, T; Kawabe, K; Kitamura, T; Moriyama, N; Narita, Y; Nishimatsu, H; Takeuchi, T; Ueki, K; Ueki, T | 1 |
| Angeloni, D; Braga, E; Dreijerink, K; Duh, FM; Geil, L; Kashuba, V; Klein, G; Kuzmin, I; Lerman, MI; Li, J; Minna, JD; Protopopov, A; Stanbridge, EJ; Zabarovsky, ER; Zbar, B | 1 |
| Dahiya, R; Franks, J; Ishii, N; Li, LC; Nakajima, K; Nojima, D; Ribeiro-Filho, L | 1 |
| Dallol, A; Forgacs, E; Kishida, T; Latif, F; Maher, ER; Martinez, A; Minna, JD; Rabbitts, P; Sekido, Y; Walker, R | 1 |
| Hasegawa, M; Hori, M; Uehara, Y; Umezawa, H | 1 |
1 trial(s) available for azacitidine and Cancer of Kidney
| Article | Year |
|---|---|
Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Renal Cell; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Fetal Hemoglobin; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Injections, Intravenous; Injections, Subcutaneous; Interleukin-2; Kidney Neoplasms; Leukocytes, Mononuclear; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Predictive Value of Tests; Treatment Outcome | 2006 |
54 other study(ies) available for azacitidine and Cancer of Kidney
| Article | Year |
|---|---|
Hypermethylation of RASSF1A gene in pediatric rhabdoid tumor of the kidney and clear cell sarcoma of the kidney.
Topics: Azacitidine; Cell Line, Tumor; Child; Decitabine; DNA Methylation; Humans; Kidney; Kidney Neoplasms; Nephroma, Mesoblastic; Rhabdoid Tumor; Sarcoma, Clear Cell; Tumor Suppressor Proteins | 2023 |
Ginsenoside Rg3 inhibits renal cell carcinoma cell migration, invasion, colony formation, and tube formation and enhances apoptosis through promoting the DNA demethylation and histone acetylation.
Topics: Acetylation; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; DNA Demethylation; DNA Methylation; Histone Deacetylases; Histones; Humans; Kidney Neoplasms; Tumor Suppressor Protein p53 | 2023 |
PON1 hypermethylation is associated with progression of renal cell carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aryldialkylphosphatase; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Databases, Genetic; Disease Progression; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Kidney Neoplasms; Mice; Mice, Nude; Sunitinib; Transplantation, Heterologous | 2019 |
Moving beyond hydroxychloroquine: the novel lysosomal autophagy inhibitor ROC-325 shows significant potential in preclinical studies.
Topics: Animals; Antineoplastic Agents; Autophagy; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Hydroxychloroquine; Kidney Neoplasms; Leukemia, Myeloid, Acute; Lysosomes; Mice | 2019 |
Combined Treatment with Valproic Acid and 5-Aza-2'-Deoxycytidine Synergistically Inhibits Human Clear Cell Renal Cell Carcinoma Growth and Migration.
Topics: Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; Drug Synergism; G1 Phase; Humans; Kidney Neoplasms; Valproic Acid | 2018 |
Epigenetic regulation of microRNA expression in renal cell carcinoma.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Kidney Neoplasms; MicroRNAs; Promoter Regions, Genetic; RNA; Vorinostat | 2013 |
CpG dinucleotide-specific hypermethylation of the TNS3 gene promoter in human renal cell carcinoma.
Topics: Azacitidine; Base Pairing; Base Sequence; Carcinoma, Renal Cell; Case-Control Studies; Computational Biology; CpG Islands; DNA Methylation; Exons; HEK293 Cells; Humans; Kidney Neoplasms; Microfilament Proteins; Molecular Sequence Data; Promoter Regions, Genetic; Reproducibility of Results; Sequence Analysis, DNA; Tensins | 2013 |
Reduced expression of Slit2 in renal cell carcinoma.
Topics: Aged; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HEK293 Cells; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Jurkat Cells; Kidney Neoplasms; Male; Middle Aged; Nerve Tissue Proteins | 2014 |
Epigenetic silencing of Na,K-ATPase β 1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Humans; Kidney Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Von Hippel-Lindau Tumor Suppressor Protein | 2014 |
Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; HSP27 Heat-Shock Proteins; Humans; Kidney Neoplasms; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
Interferon regulatory factor 8 functions as a tumor suppressor in renal cell carcinoma and its promoter methylation is associated with patient poor prognosis.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Female; G2 Phase Cell Cycle Checkpoints; Genes, Tumor Suppressor; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Interferon Regulatory Factors; Kidney Neoplasms; M Phase Cell Cycle Checkpoints; Male; Prognosis; Promoter Regions, Genetic | 2014 |
Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.
Topics: Aged; Azacitidine; Calcium-Binding Proteins; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; CpG Islands; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Male; Middle Aged; Nerve Tissue Proteins; Promoter Regions, Genetic | 2015 |
Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways.
Topics: Aged; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Bone Morphogenetic Protein 2; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, cdc; Humans; Kidney Neoplasms; Kidney Tubules; Male; Middle Aged; Neoplasm Proteins; Nephrectomy; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Transfection; Treatment Outcome | 2015 |
Demethylation of miR-10b plays a suppressive role in ccRCC cells.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; MicroRNAs; Neoplasm Invasiveness; Nuclear Proteins; Phenylbutyrates; Promoter Regions, Genetic; Time Factors; Transfection; Twist-Related Protein 1 | 2015 |
Decitabine induces G2/M cell cycle arrest by suppressing p38/NF-κB signaling in human renal clear cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Carrier Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Decitabine; Dose-Response Relationship, Drug; Down-Regulation; G2 Phase Cell Cycle Checkpoints; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Membrane Proteins; NF-kappa B; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Ubiquitin Thiolesterase | 2015 |
5-Aza-2'-Deoxycytidine and CDDP Synergistically Induce Apoptosis in Renal Carcinoma Cells via Enhancing the APAF-1 Activity.
Topics: Antineoplastic Agents; Apoptosis; Apoptotic Protease-Activating Factor 1; Azacitidine; Cell Line, Tumor; Cisplatin; Decitabine; DNA Methylation; Drug Synergism; Humans; Kidney Neoplasms | 2015 |
The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation.
Topics: Adult; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Transformed; Cell Line, Tumor; CpG Islands; DNA Helicases; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Kidney Neoplasms; Nerve Tissue Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Proteins | 2016 |
Oxidative stress-induced epigenetic changes associated with malignant transformation of human kidney epithelial cells.
Topics: Acetylation; Animals; Azacitidine; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Enzyme Inhibitors; Epigenesis, Genetic; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Hydrogen Peroxide; Kidney; Kidney Neoplasms; Mice, Nude; Oxidants; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2017 |
Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Renal Cell; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kelch-Like ECH-Associated Protein 1; Kidney Neoplasms; Male; Middle Aged; NF-E2-Related Factor 2; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Survival Analysis | 2017 |
BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer.
Topics: Anticarcinogenic Agents; Azacitidine; Cell Cycle; Cell Cycle Proteins; Cell Survival; Chromatin; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Enzyme Inhibitors; Genes, Tumor Suppressor; Genistein; Histones; Humans; Kidney Neoplasms; Promoter Regions, Genetic; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2009 |
Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways.
Topics: Adult; Aged; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Cycle; Chromatin Immunoprecipitation; Decitabine; Disease Progression; Female; Gene Silencing; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Male; Middle Aged; Wnt Proteins | 2009 |
Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Proliferation; Connexins; Decitabine; Deoxycytidine; Down-Regulation; Enzyme Activation; Gap Junction beta-1 Protein; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Kidney Neoplasms; Signal Transduction; Transcriptional Activation; Up-Regulation; Vinblastine | 2010 |
Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Caspase 3; Cell Proliferation; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Male; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Wnt Proteins | 2011 |
Functional and epigenetic characterization of the KRT19 gene in renal cell neoplasms.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Keratin-19; Kidney; Kidney Neoplasms; Male; Middle Aged; Promoter Regions, Genetic | 2011 |
Noncytotoxic differentiation treatment of renal cell cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cellular Senescence; Cytotoxins; Decitabine; DNA Damage; Humans; Kidney Neoplasms; Mice; Mice, Nude; Xenograft Model Antitumor Assays | 2011 |
5-aza-2'-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel by decreasing LEF1/phospho-β-catenin expression.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; beta Catenin; Blotting, Western; Carcinoma, Renal Cell; Decitabine; Drug Synergism; Humans; Immunohistochemistry; Kidney Neoplasms; Lymphoid Enhancer-Binding Factor 1; Mice; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection; Xenograft Model Antitumor Assays | 2011 |
Rap1GAP regulates renal cell carcinoma invasion.
Topics: Azacitidine; Cadherins; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Humans; Integrins; Kidney Neoplasms; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Small Interfering; Transfection | 2012 |
Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Breast Neoplasms; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Decitabine; Depsipeptides; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Histone Deacetylase Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Kidney Neoplasms; Methyltransferases; Recombinant Proteins; Tumor Suppressor Proteins | 2012 |
Gene expression profiling of the synergy of 5-aza-2'-deoxycytidine and paclitaxel against renal cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Blotting, Western; Carcinoma, Renal Cell; Decitabine; Drug Synergism; Gene Expression Profiling; Humans; Kidney Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2012 |
Renal tumours in a Tsc1+/- mouse model show epigenetic suppression of organic cation transporters Slc22a1, Slc22a2 and Slc22a3, and do not respond to metformin.
Topics: Animals; Azacitidine; Blotting, Western; Catecholamine Plasma Membrane Transport Proteins; Decitabine; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Hypoglycemic Agents; Immunohistochemistry; Kidney; Kidney Neoplasms; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Knockout; Multiprotein Complexes; Organic Cation Transport Proteins; Organic Cation Transporter 2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; TOR Serine-Threonine Kinases; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2013 |
5-aza-2'-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: immunotherapeutic implications.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Decitabine; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Humans; Immunotherapy; Kidney Neoplasms; Melanoma-Specific Antigens; Membrane Proteins; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Precipitin Tests; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 2002 |
DNA mismatch repair genes in renal cell carcinoma.
Topics: Azacitidine; Base Pair Mismatch; Blotting, Western; Carcinoma, Renal Cell; Decitabine; DNA Modification Methylases; DNA Repair; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunohistochemistry; Kidney Neoplasms; Male; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2003 |
The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine.
Topics: Adenocarcinoma, Clear Cell; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; Disease Models, Animal; DNA Methylation; Gene Silencing; Humans; Kidney Neoplasms; Mice; Pyrimidine Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein | 2004 |
Restoration of expression of transforming growth factor-beta type II receptor in murine renal cell carcinoma (renca) cells by 5-Aza-2'-deoxycytidine.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Kidney Neoplasms; Mice; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Methylation of the gamma-catenin gene is associated with poor prognosis of renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Renal Cell; CpG Islands; Cytoskeletal Proteins; Decitabine; Desmoplakins; Disease Progression; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Female; gamma Catenin; Humans; Kidney; Kidney Neoplasms; Male; Middle Aged; Mutation; Prognosis; Promoter Regions, Genetic; Survival Rate | 2005 |
Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma; Carcinoma, Renal Cell; Colonic Neoplasms; Decitabine; DNA Methylation; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Isoenzymes; Kidney Neoplasms; Promoter Regions, Genetic; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2005 |
Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Loss of Heterozygosity; Male; Membrane Proteins; Middle Aged; Mitochondrial Proteins; RNA, Messenger; Transfection; Tumor Suppressor Proteins | 2006 |
A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Southern; Decitabine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Gene Dosage; Humans; Kidney Neoplasms; Leukemia, Myeloid, Acute; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Reproducibility of Results; Sulfites; Wilms Tumor | 2006 |
Identification of novel target genes by an epigenetic reactivation screen of renal cancer.
Topics: Adult; Aged; Azacitidine; Base Sequence; Carcinoma, Renal Cell; Cell Line, Tumor; Collagen Type I; Collagen Type I, alpha 1 Chain; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Kidney Neoplasms; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Up-Regulation | 2006 |
Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Interferon-alpha; Interferon-beta; Interferons; Intracellular Signaling Peptides and Proteins; Kidney Neoplasms; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Proteins; Polymerase Chain Reaction; Transplantation, Heterologous; Up-Regulation | 2006 |
Aberrant promoter methylation of the ABCG2 gene in renal carcinoma.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Azacitidine; Base Sequence; Carcinoma, Renal Cell; Cell Line, Tumor; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Histones; Humans; Kidney Neoplasms; Lysine; Neoplasm Proteins; Promoter Regions, Genetic; Protein Binding; Transcription, Genetic; Von Hippel-Lindau Tumor Suppressor Protein | 2006 |
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cells, Cultured; Cytidine; Death-Associated Protein Kinases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Kidney; Kidney Neoplasms; Male; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms | 2006 |
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors.
Topics: Adolescent; Adult; Aged; Azacitidine; Base Sequence; Child; Decitabine; DNA Methylation; Female; Gene Dosage; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Immunohistochemistry; Kidney Neoplasms; Male; Membrane Proteins; Middle Aged; Molecular Sequence Data; Neoplasm Proteins; Nerve Tissue Proteins; RNA, Messenger; Transcriptional Activation; Wilms Tumor | 2007 |
DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Immunoprecipitation; Kidney Neoplasms; Membrane Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Wnt Proteins | 2008 |
The tumorigenicity of 5-azacytidine in the male Fischer rat.
Topics: Animals; Azacitidine; DNA; Kidney Neoplasms; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphatic Diseases; Male; Methylation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Skin Neoplasms; Testicular Neoplasms | 1984 |
Region-specific methylation of the parathyroid hormone-related peptide gene determines its expression in human renal carcinoma cell lines.
Topics: Azacitidine; Blotting, Southern; Chloramphenicol O-Acetyltransferase; DNA Probes; DNA, Neoplasm; Gene Expression; Humans; Kidney Neoplasms; Methylation; Neoplasm Proteins; Parathyroid Hormone-Related Protein; Protein Biosynthesis; Proteins; Recombinant Fusion Proteins; Restriction Mapping; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1993 |
Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors.
Topics: Adult; Alleles; Azacitidine; Base Sequence; Cell Line; Child; Chromosomes, Human, Pair 11; Cyclin-Dependent Kinase Inhibitor p57; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; Enzyme Inhibitors; Female; Fetus; Gene Expression Regulation; Genes, Tumor Suppressor; Genomic Imprinting; Heterozygote; Humans; Infant, Newborn; Kidney Neoplasms; Male; Muscle Proteins; Nuclear Proteins; RNA, Long Noncoding; RNA, Messenger; RNA, Untranslated; Wilms Tumor | 1996 |
Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers.
Topics: Azacitidine; Brain Neoplasms; CpG Islands; Decitabine; DNA Methylation; Humans; Kidney Neoplasms; Tissue Inhibitor of Metalloproteinase-3 | 1999 |
Activation of the MN/CA9 gene is associated with hypomethylation in human renal cell carcinoma cell lines.
Topics: Antigens, Neoplasm; Azacitidine; Base Sequence; Carcinoma, Renal Cell; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Molecular Sequence Data; Tumor Cells, Cultured | 2000 |
Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo.
Topics: Animals; Apoptosis; Azacitidine; Caspase 1; Cell Division; Coloring Agents; Decitabine; DNA Methylation; DNA, Complementary; Enzyme Inhibitors; fas Receptor; Gene Silencing; Genetic Vectors; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Kidney Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured | 2001 |
The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Adhesion; Cell Division; Chromosome Mapping; Chromosomes, Human, Pair 3; DNA Methylation; DNA Primers; DNA, Neoplasm; Doxycycline; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Kidney Neoplasms; Neoplasm Proteins; Promoter Regions, Genetic; Recombinant Proteins; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
CpG methylation of promoter region inactivates E-cadherin gene in renal cell carcinoma.
Topics: Azacitidine; Cadherins; Carcinoma, Renal Cell; Cells, Cultured; CpG Islands; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Enzyme Inhibitors; Gene Silencing; Humans; Immunoenzyme Techniques; Kidney Neoplasms; Neoplasm Staging; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Transcription, Genetic | 2001 |
Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.
Topics: Animals; Azacitidine; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Drosophila melanogaster; Drosophila Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Kidney Neoplasms; Loss of Heterozygosity; Lung Neoplasms; Mutation, Missense; Nerve Tissue Proteins; Promoter Regions, Genetic; Receptors, Immunologic; Roundabout Proteins; Sequence Homology, Nucleic Acid; Tumor Cells, Cultured | 2002 |
Differential sensitivity of RSVts (temperature-sensitive Rous-sarcoma virus)-infected rat kidney cells to nucleoside antibiotics at permissive and non-permissive temperatures.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azacitidine; Cell Division; Cell Line; Kidney; Kidney Neoplasms; Purines; Pyrimidines; Rats; Ribonucleosides; Sarcoma, Avian; Temperature | 1985 |