azacitidine and Cancer of Head

azacitidine has been researched along with Cancer of Head in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's2 (7.41)18.2507
2000's10 (37.04)29.6817
2010's13 (48.15)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Atri, S; Hodjat, M; Nasoohi, N1
Bellinger, G; Bhatia, A; Biktasova, A; Burtness, B; Deshpande, HA; Gary, C; Hajek, M; Issaeva, N; Judson, B; Mehra, S; Sewell, A; Yarbrough, WG1
Arroyo-Solera, I; Barnadas, A; Casanova, I; Céspedes, MV; Gallardo, A; León, X; López, M; López-Pousa, A; Mangues, MA; Mangues, R; Pavón, MA; Quer, M; Téllez-Gabriel, M1
Achdjian, S; Dang, D; Katz, SG; Schmidt, BL; Viet, CT; Ye, Y1
Kim, EJ; Kim, JS; Kim, SH; Kim, SM; Kim, SY; Lee, M1
Arcaro, KF; Chen, X; Furdui, CM; Liu, L; Mims, J; Punska, EC; Tsang, AW; Williams, KE; Zhao, W; Zhou, X1
Li, SS; Liu, JJ; Liu, ZH; Yang, XM1
Arab, K; Bennett, KL; Claus, R; Dyckhoff, G; Herpel, E; Karpenko, M; Lin, MT; Plass, C; Plinkert, P; Smiraglia, D1
De Schutter, H; Isebaert, S; Kimpe, M; Nuyts, S1
Beder, LB; Fujihara, K; Fukushima, K; Grenman, R; Gunduz, E; Gunduz, M; Hotomi, M; Shimada, J; Shimizu, K; Tamura, S; Yamanaka, N; Yaykasli, K1
Brentani, H; Calmon, MF; Camargo, AA; Carraro, DM; Cury, PM; da Silva, AM; de Carvalho, AF; Kaneto, CM; Kowalski, LP; Mota, LD; Moura, RP; Nishimoto, IN; Nunes, FD; Pinheiro, DG; Rahal, P; Rodrigues, RV; Silva, SD; Silva, WA; Soares, FA; Tajara, EH; Torres, C; Valentini, SR; Zanelli, CF1
Brieger, J; Fruth, K; Hedrich, J; Mann, SA; Mann, WJ; Pogozelski, B; Pongsapich, W1
Cheong, SC; Gan, CP; Hamid, S; Hor, SY; Ismail, SM; Saunders, N; Teo, SH; Wan Mustafa, WM; Zain, RB1
Accardi, R; Boffetta, P; Brennan, P; Calabrese, L; Chiesa, F; Creveaux, M; Cuenin, C; Curado, MP; Daudt, A; Fathallah, I; Gheit, T; Herceg, Z; Hussain, I; Koifman, S; Maffini, FA; Malfroy, M; Matos, E; Menezes, AM; Saulnier, A; Sebastian, S; Shahzad, N; Shukla, R; Siouda, M; Sylla, BS; Tommasino, M; Torrente, M; Vaissière, T; Wünsch-Filho, V; Yue, J; Zaridze, D1
Brieger, J; Fruth, K; Koutsimpelas, D; Mann, SA; Mann, WJ; Pongsapich, W1
Brieger, J; Heinrich, U; Koutsimpelas, D; Mann, S; Mann, WJ; Pongsapich, W1
Bermejo, JL; Campos, B; Chaisaingmongkol, J; Claus, R; Dyckhoff, G; Geiselhart, L; Herold-Mende, C; Herpel, E; Lasitschka, F; Oakes, CC; Plass, C; Popanda, O; Schmezer, P; Warta, R1
Califano, JA; Demokan, S; Glazer, CA; Hennessey, P; Loyo, M; Mydlarz, W; Ochs, MF; Pattani, KM; Schussel, J; Smith, IM; Soudry, E; Sun, W; Wang, H1
Acuña, C; Chavez, A; Dueñas-Gonzalez, A; Lizano, M; Mariscal, I; Perez-Cardenas, E; Salazar, AM; Segura-Pacheco, B; Taja-Chayeb, L; Trejo-Becerril, C1
Benoit, NE; Dong, SM; Kuzmin, I; Lerman, MI; Sidransky, D; Sun, DI1
Bone, JR; Briggs, KL; Clayman, GL; Coombes, MM; Dent, SY; El-Naggar, AK1
Choi, EJ; Kim, JS; Kim, YH; Seo, JH; Whang, YM; Yoo, YD1
Brena, RM; Lang, JC; Lin, M; Morrison, CD; Otterson, GA; Plass, C; Schuller, DE; Smiraglia, DJ; Smith, LT1
Bennett, KL; Eng, C; Hackanson, B; Lang, JC; Morrison, CD; Plass, C; Schuller, DE; Smith, LT; Weber, F1
Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D1
Hynes, HE; Keppen, M; Kuebler, JP; Metch, B; Schuller, DE1
Braakhuis, BJ; Leyva, A; Snow, GB; van Dongen, GA; van Walsum, M1

Trials

1 trial(s) available for azacitidine and Cancer of Head

ArticleYear
Phase II study of fazarabine in advanced head and neck cancer. A Southwest Oncology Group study.
    Investigational new drugs, 1991, Volume: 9, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged

1991

Other Studies

26 other study(ies) available for azacitidine and Cancer of Head

ArticleYear
Azacitidine, as a DNMT Inhibitor Decreases hTERT Gene Expression and Telomerase Activity More Effective Compared with HDAC Inhibitor in Human Head and Neck Squamous Cell Carcinoma Cell Lines.
    Current molecular pharmacology, 2021, Volume: 14, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Survival; DNA Methylation; DNA Modification Methylases; Drug Development; Enzyme Activation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Peptide Fragments; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Telomerase

2021
Demethylation Therapy as a Targeted Treatment for Human Papillomavirus-Associated Head and Neck Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Dec-01, Volume: 23, Issue:23

    Topics: Animals; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Mice, Nude; Papillomaviridae; Papillomavirus Infections; Xenograft Model Antitumor Assays

2017
High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma.
    Cancer medicine, 2013, Volume: 2, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cell Movement; Cisplatin; Decitabine; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Keratinocytes; Male; Middle Aged; Prognosis; rab GTP-Binding Proteins; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome

2013
Decitabine rescues cisplatin resistance in head and neck squamous cell carcinoma.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cisplatin; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Transcriptome; Xenograft Model Antitumor Assays; Young Adult

2014
Radioresistance in a human laryngeal squamous cell carcinoma cell line is associated with DNA methylation changes and topoisomerase II α.
    Cancer biology & therapy, 2015, Volume: 16, Issue:4

    Topics: Antigens, Neoplasm; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Topoisomerases, Type II; DNA-Binding Proteins; Epigenesis, Genetic; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Promoter Regions, Genetic; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Transcription, Genetic

2015
Analysis of DNA methylation and gene expression in radiation-resistant head and neck tumors.
    Epigenetics, 2015, Volume: 10, Issue:6

    Topics: Azacitidine; Cell Line, Tumor; CpG Islands; Cyclin D2; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Kruppel-Like Factor 4; Promoter Regions, Genetic; Radiation Tolerance

2015
Association of RUNX3 Methylation with Clinical Outcome and Cell Migration/Invasion in Laryngeal Squamous Cell Carcinoma.
    Cancer investigation, 2016, Volume: 34, Issue:2

    Topics: Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Core Binding Factor Alpha 3 Subunit; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck; Time Factors

2016
Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma.
    Cancer research, 2008, Jun-15, Volume: 68, Issue:12

    Topics: Azacitidine; Carcinoma, Squamous Cell; Cation Transport Proteins; Colony-Forming Units Assay; DNA Methylation; Epigenesis, Genetic; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; GTP Phosphohydrolases; Head and Neck Neoplasms; Homeodomain Proteins; Humans; Microtubule-Associated Proteins; Monocarboxylic Acid Transporters; Mucous Membrane; Nerve Tissue Proteins; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Septins; Transcription Factors

2008
A systematic assessment of radiation dose enhancement by 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma.
    International journal of radiation oncology, biology, physics, 2009, Mar-01, Volume: 73, Issue:3

    Topics: Acetylation; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Reverse Transcriptase Polymerase Chain Reaction; Tumor Stem Cell Assay

2009
T-lymphocyte maturation-associated protein gene as a candidate metastasis suppressor for head and neck squamous cell carcinomas.
    Cancer science, 2009, Volume: 100, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Heterozygote; Humans; Male; Membrane Transport Proteins; Middle Aged; Mutation; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Neoplasm Metastasis; Proteolipids; RNA, Messenger

2009
Epigenetic silencing of CRABP2 and MX1 in head and neck tumors.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:12

    Topics: Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Head and Neck Neoplasms; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Myxovirus Resistance Proteins; Oligonucleotide Array Sequence Analysis; Prognosis; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; Tissue Array Analysis

2009
Demethylation treatment restores hic1 expression and impairs aggressiveness of head and neck squamous cell carcinoma.
    Oral oncology, 2010, Volume: 46, Issue:9

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Kruppel-Like Transcription Factors; Male; Middle Aged; Neoplasm Invasiveness; Promoter Regions, Genetic

2010
Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.
    Head & neck, 2012, Volume: 34, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Decitabine; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Humans; Squamous Cell Carcinoma of Head and Neck; Tretinoin; Valproic Acid

2012
Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers.
    International journal of cancer, 2012, Jun-01, Volume: 130, Issue:11

    Topics: Adult; Aged; Azacitidine; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Male; Middle Aged; Phosphoproteins; Promoter Regions, Genetic; Risk Factors; RNA-Binding Proteins; Tumor Suppressor Proteins

2012
Pharmacological genome demethylation increases radiosensitivity of head and neck squamous carcinoma cells.
    International journal of molecular medicine, 2012, Volume: 29, Issue:3

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Promoter Regions, Genetic; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Transcriptional Activation

2012
Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells.
    Oncology reports, 2012, Volume: 27, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Azacitidine; Base Sequence; Carcinoma, Squamous Cell; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; CpG Islands; Dealkylation; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Female; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Middle Aged; Molecular Sequence Data; MutL Protein Homolog 1; Nuclear Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Sequence Analysis, DNA; Tumor Suppressor Proteins

2012
Epigenetic screen of human DNA repair genes identifies aberrant promoter methylation of NEIL1 in head and neck squamous cell carcinoma.
    Oncogene, 2012, Dec-06, Volume: 31, Issue:49

    Topics: Aged; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Glycosylases; DNA Methylation; DNA Repair; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Head and Neck Neoplasms; Humans; Keratinocytes; Male; Middle Aged; Promoter Regions, Genetic; Reference Values; Squamous Cell Carcinoma of Head and Neck

2012
MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Reproducibility of Results; Transcriptional Activation

2012
Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Hydralazine; Mice; Mice, Nude; Procainamide; Receptors, Estrogen; Receptors, Retinoic Acid; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2003
Epigenetic inactivation of RASSF1A in head and neck cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Sep-01, Volume: 9, Issue:10 Pt 1

    Topics: Azacitidine; Carcinoma; Cell Line, Tumor; Decitabine; DNA; DNA Methylation; Down-Regulation; Head and Neck Neoplasms; Humans; Microsatellite Repeats; Papillomaviridae; Point Mutation; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Isoforms; RNA; Sequence Analysis, DNA; Sulfites; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2003
Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation.
    Oncogene, 2003, Dec-04, Volume: 22, Issue:55

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Squamous Cell; Decitabine; DNA Methylation; Gene Silencing; Genes, p16; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids

2003
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:5

    Topics: Acetylation; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin

2005
Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Jan-24, Volume: 103, Issue:4

    Topics: Animals; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Cell Cycle; Cell Line, Tumor; Chromosomes, Human, Pair 6; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Epigenesis, Genetic; Gene Expression Regulation; Gene Silencing; Genome; Head and Neck Neoplasms; Humans; Immunohistochemistry; Loss of Heterozygosity; Luciferases; Lung; Lung Neoplasms; Mice; Mice, Nude; Models, Genetic; Neoplasm Transplantation; Open Reading Frames; Plasmids; Promoter Regions, Genetic; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Sulfites; Time Factors; Transfection

2006
Tumor suppressor activity of CCAAT/enhancer binding protein alpha is epigenetically down-regulated in head and neck squamous cell carcinoma.
    Cancer research, 2007, May-15, Volume: 67, Issue:10

    Topics: Azacitidine; Carcinoma, Squamous Cell; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Loss of Heterozygosity; Neoplasm Metastasis; Transfection

2007
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
    Nature medicine, 1995, Volume: 1, Issue:7

    Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured

1995
Preclinical antitumor activity of 5-aza-2'-deoxycytidine against human and neck cancer xenografts [corrected].
    Investigational new drugs, 1988, Volume: 6, Issue:4

    Topics: Animals; Antineoplastic Agents; Azacitidine; Decitabine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Head and Neck Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation

1988