azacitidine and Breast Cancer

azacitidine has been researched along with Breast Cancer in 248 studies

Research

Studies (248)

TimeframeStudies, this research(%)All Research%
pre-19906 (2.42)18.7374
1990's14 (5.65)18.2507
2000's98 (39.52)29.6817
2010's126 (50.81)24.3611
2020's4 (1.61)2.80

Authors

AuthorsStudies
Gun, M; Hong, XY; Wang, Q1
Bear, HD; Camarena, C; Conrad, DH; Damle, SR; Gilmer, JS; Graham, LJ; Luker, AJ; Martin, RK; Smith, TM; Zellner, MP1
Lu, A; Ring, BZ; Su, L; Tanaka, Y; Wang, W; Wang-Renault, SF; Weng, J1
Andrews, C; Maze, D; Murphy, T; Sibai, H1
Ahmad, M; Akhtar Ali, M; Ali, M; Anjum, RS; Aslam, B; Farooq, K; Hassan, U; Javed, M; Munir, T; Mustafa, T; Mutahir, Z; Shahzad, N; Shakoori, AR; Tasneem, F; Umer, M1
Chang, YW; Singh, KP1
Khan, GN; Kim, EJ; Lee, SH; Shin, TS1
Acun, T; Doberstein, N; Gemoll, T; Habermann, JK; Oztas, E; Ried, T; Thorns, C1
Chen, Y; Li, Z; Luo, D; Tian, W; Zhang, X1
Baura, VA; Biembengut, IV; Chequin, A; Costa, FF; de O Pedrosa, F; de Souza, EM; Klassen, G; Klassen, LMB; Manica, GCM; Ramos, EAS; Toledo, MB1
Balko, JM; Gonzalez-Ericsson, PI; Li, H; Liu, F; Luo, N; Manning, HC; Nickels, ML; Nixon, MJ; Opalenik, SR; Sanchez, V; Sanders, ME; Tantawy, MN; Zahnow, CA1
Abu-Irmaileh, B; Al-Majawleh, M; Hamadneh, L; Hasan, M; Jarrar, Y; Shraim, S1
Bharti, R; Das, AK; Dey, G; Mandal, M1
Curtis, SA; Folkers, A; Medoff, E; Mixon, R; Shallis, RM; Xu, ML; Zeidan, AM1
Chen, Y; Cui, X; Hu, H; Jiao, Y; Li, S; Lin, L; Lv, X; Song, E; Wang, M; Yao, H; Yu, F1
Arafa, M; Balasubramanian, S; Brown, NJ; Higham, SE; Perunovic, B; Rehman, I1
Bendinelli, P; Desiderio, MA; Locatelli, A; Maroni, P; Matteucci, E1
Charalambous, C; Constantinou, AI; Papageorgis, P; Pitta, CA1
Brown, K; Gillespie, KM; Holly, JM; Jarrett, C; Perks, CM; Zeng, L1
Brenner, C; Cryderman, DE; Fagan, RL; Kopelovich, L; Wallrath, LL1
Boffelli, D; Coppé, JP; Di Noia, JM; Heo, SJ; Lee, EL; Martin, DI; Muñoz, DP; Takayama, S1
Ge, YL; Han, LL; Hou, L; Lin, DL; Ma, ZL; Wu, L; Zhou, MJ1
Mahajan, N; Sabherwal, Y; Zhang, M1
Anastasiadis, PZ; Andorfer, CA; Borges, S; Döppler, H; Geiger, XJ; Perez, EA; Storz, P; Sun, Z; Thompson, E1
Chik, F; Machnes, Z; Szyf, M1
Al-Nakhle, H; Bell, SM; Burns, PA; Cummings, M; Hanby, AM; Hughes, TA; Lane, S; Parker, MD; Smith, L; Speirs, V1
Azevedo-Pouly, AC; Elgamal, OA; Gusev, Y; Jiang, J; Park, JK; Roopra, A; Schmittgen, TD1
Ang, WT; Ho, GH; Koh, QM; Koong, HN; Lin, VC; Sivaramakrishnan, G; Sun, Y1
Anderton, DL; Arcaro, KF; Lee, MP; Pentecost, BT; Williams, KE1
Jazirehi, AR; Torres-Collado, AX1
Geng, CZ; Hou, SY; Liu, WH; Lü, WH; Sang, MX; Shan, BE; Xu, YY1
Clarke, K; Qin, W; Sauter, ER; Weiland, T; Zhang, K1
Dai, Q; Gu, Y; Guo, S; Pan, S; Yu, Y; Zhang, W; Zhao, F1
Brglez, V; Lambeau, G; Petan, T; Pucer, A; Pungerčar, J1
Borges, S; Döppler, HR; Storz, P1
Al-Rayyan, N; Cheng, A; Elbedewy, A; Ivanova, MM; Klinge, CM; Litchfield, LM; Radde, BN1
Bai, SY; Jiao, F; Ma, Y; Wang, J; Wang, X; Yan, ZH; Yu, Y; Yue, Z1
Chang, HW; Chen, CY; Hou, MF; Huang, CJ; Hung, TW; Tseng, CN; Wang, HC; Yuan, SS1
Huang, S; Luo, M; Ning, Q; Qin, Y; Shao, S; Yuan, N; Zhang, X; Zhao, X; Zuo, X1
Motevalli, A; Roberts, T; Slijepcevic, P; Virmouni, SA; Yasaei, H1
Du, M; Su, XM; Xing, YJ; Zhang, T1
Fiegl, H; Fleischer, M; Hollmann, MW; Lirk, P; Weber, NC1
Abba, MC; Cattaneo, ER; Coleman, RA; Garcia-Fabiani, MB; Gonzalez-Baro, MR; Lacunza, E; Montanaro, MA; Pellon-Maison, M; Quiroga, IY; Soler-Gerino, MC1
Capobianco, E; Cinti, C; El Baroudi, M; La Sala, D1
Arakelian, A; Bhattacharya, B; Cheishvili, D; Chik, F; Hallett, M; Li, CC; Rabbani, SA; Suderman, M; Szyf, M1
Braun-Prado, K; Camargo, AA; Chequin, A; Costa, ET; Costa, FF; Klassen, G; Klassen, LM; Manica, GC; Pedrosa, Fde O; Pereira, IT; Ramos, EA; Souza, EM1
Barrio-Real, L; Benedetti, LG; Cho, S; Engel, N; Kazanietz, MG; Sukumar, S; Tu, Y1
Calvo, F; Daunay, A; Djaafri, I; Fauvel, F; Idbaih, A; Janin, A; Khayati, F; Lebbé, C; Menashi, S; Mourah, S; Podgorniak, MP; Sadoux, A; Setterblad, N; Soulier, J; Teixeira, L; Tost, J1
Katagiri, T; Lo, PH; Matsuda, K; Nakamura, Y; Tanikawa, C1
Du, XJ; Jun, W; Li, SY; Liu, Y; Shen, S; Sun, R; Wang, HX; Zhu, YH1
Fan, JJ; Gao, Y; Li, HY; Li, Y; Ma, DM; Mai, L; Song, FZ; Wu, JY; Zeng, F; Zhang, J1
Heldin, CH; Idås, O; Kahata, K; Moustakas, A; Tan, EJ; Thuault, S1
Mahalingaiah, PK; Singh, KP; Treas, JN; Tyagi, T1
ChuanYi, Z; Hui, L; Hui, Z; Wenting, Y; XuQun, H; Yiling, C1
Borcherding, NC; Mahauad-Fernandez, WD; Okeoma, CM; Zhang, W1
Chang, CH; Chang, SC; Chen, CY; Chuu, CP; King, KL; Kung, HJ; Shiah, SG; Su, LC; Wen, HC1
Jaksic, O; Kusec, R; Lasan-Trcic, R; Lucijanic, M; Pejsa, V; Stoos-Veic, T1
Ditzel, HJ; Gjerstorff, MF; Maheswaran, E; Pedersen, CB1
Berdasco, M; Blanco-Luquin, I; Coca, V; Cordoba, A; De La Cruz, S; Escors, D; Guerrero-Setas, D; Ibañez, B; Illarramendi, JJ; Jauregui, I; Kochan, G; Lera, JM; Liechtenstein, T; Perez-Janices, N; Torrea, N; Vicente-Garcia, F1
Mei, M; Tian, WP; Zhang, YY1
Gopinadh, J; Klar, AS; Kleber, S; Renner, C; Wadle, A1
Bendinelli, P; Desiderio, MA; Disanza, A; Maroni, P; Matteucci, E1
Ema, A; Enomoto, T; Katoh, H; Kikuchi, M; Kojo, K; Kosaka, Y; Minatani, N; Sawanobori, M; Sengoku, N; Tanino, H; Ushiku, H; Waraya, M; Watanabe, M; Yamashita, K1
Argyle, DJ; Coonrod, SA; Curtis, TM; Harman, RM; Van de Walle, GR1
Kalayoğlu Beşışık, S; Turan Erkek, E1
Borikun, TV; Chekhun, VF; Lukianova, NY1
Iwaisako, K; Kawashima, M; Kawata, Y; Kurebayashi, J; Nishimura, T; Noda, M; Shi, G; Toi, M; Yoshida, Y; Yoshikawa, K; Yuki, K1
Barwick, BG; Bell, JS; Dwivedi, B; Kagey, JD; Kowalski, J; McCabe, MT; Vertino, PM1
Kong, X; Liu, A; Liu, J; Liu, Y; Su, Y; Sun, P; Wang, X; You, D; Yuan, L; Zhang, D; Zhang, X1
Choi, JH; Ganapathy, V; Kolhe, R; Lokeshwar, BL; Manicassamy, S; Mariappan, G; Pathania, R; Prasad, PD; Ramachandran, S; Sharma, S; Shi, H; Thakur, P; Thangaraju, M1
Baek, A; Bear, HD; Damle, SR; Graham, LJ; Manjili, MH; Payne, KK; Terracina, KP1
Guo, H; Guo, Y; Huang, T; Liu, C; Liu, Z; Peng, G; Wang, L; Wang, S; Yin, X; Yu, P; Yusufu, M; Zhao, X1
Dang, Q; Dong, B; Guo, Y; Jin, X; Li, Y; Lin, D; Liu, Y; Lu, Y; Quan, C; Ruan, Y; Song, P; Xie, Y; Yang, M; Zhao, S1
Fan, Y; Feng, Y; Kelly, K; Li, C; Li, L; Mu, J; Oberst, M; Peng, W; Ren, G; Tao, Q; Xiang, T; Ying, Y1
Bendinelli, P; Desiderio, MA; Maroni, P; Matteucci, E1
Ansari, KI; Chen, MY; Choy, C; Jandial, R; Levy, DM1
Gupta, PS; Limaye, AM; Manjegowda, MC1
Brown, KD; Demircan, B; Dyer, LM; Gerace, M; Lobenhofer, EK; Robertson, KD1
Bigl, M; Eschrich, K; Horn, LC; Jandrig, B1
Alonso, MA; Horne, HN; Lee, PS; Marks, JR; Murphy, SK; Olson, JA1
Csiszar, K; Fong, KS; Fong, SF; Hollosi, P; Yakushiji, JK1
Epstein, RJ; Xiong, J1
Brooke, DG; Datta, J; Denny, WA; Gamage, SA; Ghoshal, K; Jacob, ST; Phiasivongsa, P; Redkar, S1
Jagodzinski, PP; Piotrowska, H1
Chen, Y; Domann, FE; Hitchler, MJ; Weigel, RJ; Woodfield, GW1
Billam, M; Davidson, NE; Sobolewski, MD1
An, CH; Cho, HJ; Kang, WK; Kim, JI; Kim, JS; Kim, KH; Kim, SY; Oh, ST1
Chen, Y; Collins, C; Huo, D; Nwachukwu, C; Olopade, OI; Rowell, J; Slamon, DJ; Xu, J1
Chen, Y; Jiang, R; Qiu, H; Xiong, H; Zhuang, L1
Cruickshanks, HA; Tufarelli, C1
Ali, IY; Gupta, C; Gupta, J; Tikoo, K1
Chen, L; Fu, DY; Huang, W; Shao, ZM; Shen, ZZ; Wang, BL; Wang, ZM; Yang, WT1
Chin, K; Chua, CL; Eu, KW; Gray, JW; Ho, YM; Hong, GS; Kuo, WL; Lee, AS; Lie, DK; Ong, DC; Rudduck, C; Seow-Choen, F; Tan, PH; Wong, CY1
Jagodzinski, PP; Lianeri, M; Lutkowska, A; Pietkiewicz, PP1
Brown, I; Kastl, L; Schofield, AC2
Ashida, M; Fujikane, T; Hirata, K; Kai, M; Maruyama, R; Nishidate, T; Nishikawa, N; Nojima, M; Ohe-Toyota, M; Ohmura, T; Sasaki, Y; Suzuki, H; Tokino, T; Toyota, M1
Chan, E; Marquez, VE; Sun, F; Wu, Z; Yang, X; Yu, Q1
Chai, XJ; Ge, YJ; Luan, J; Qin, Y; Yang, WL; Zhang, YC1
Jang, YK; Park, SH; Yu, SE1
Chaudhary, PM; Matta, H; Punj, V1
An, SX; Chen, XL; Cui, W; Li, BL; Lu, YY; Mi, XY; Song, M; Wang, EH; Wang, LH; Wen, YY; Xu, M; Zhao, J1
Cheng, SY; Fu, J; Hu, J; Qu, Z; Xiao, G; Yan, P1
Bazarov, AV; Hines, WC; Mukhopadhyay, R; Yaswen, P1
Fackler, M; Gabrielson, E; Marik, R; Stearns, V; Sukumar, S; Umbricht, CB; Zeiger, MA1
Mirza, S; Pandya, P; Ralhan, R; Sharma, G1
Chang, HL; Huang, YW; Lin, YC; Liu, S; Shu, ST; Sugimoto, Y; Wang, LS; Yan, P; Ye, W1
Inoue, J; Ishida, T; Ito, T; Semba, K; Shimizu, T; Watanabe, S; Yamaguchi, N; Yamamoto, M1
Asa, SL; Ezzat, S; Zheng, L; Zhu, X1
Ahn, SG; Kang, KW; Kim, HS; Kim, SK; Kim, TH; Lee, KY; Lim, SC; Phuong, NT; Yoon, JH1
Jang, YK; Park, SH; Shin, JE1
Bast, RC; Feng, Y; Huan, J; Jia, L; Jin, H; Lu, Z; Yao, M; Yu, Y; Zhao, N; Zou, CF1
Ding, Q; Ding, YB; Liu, XA; Liu, YX; Shi, JP; Wang, S; Xia, JG; Xia, TS; Zhao, Y1
Hattori, N; Kikuyama, M; Okochi-Takada, E; Ushijima, T; Wakabayashi, M; Yamashita, S1
Li, W; Matsumura, F; Vogel, CF; Wong, P; Wu, D1
Bhattacharyya, B; Hallett, M; Han, ZG; Huang, J; Stefanska, B; Suderman, M; Szyf, M1
Byrne, DJ; Dobrovic, A; Fox, SB; Huang, KT; Mikeska, T; Takano, EA1
Bouizar, Z; Busato, F; Dupont, JM; Hamzaoui, H; Mourah, S; Neyret, A; Tost, J1
Kim, JH; Kim, SJ; Kim, TW1
Briones, V; Geiman, TM; Liu, S; Muegge, K; Tao, Y1
Ari, F; Colling, C; Dere, E; Honert, K; Kiechle, M; Krüger, A; Napieralski, R; Schmitt, M; Ulukaya, E1
Avraham, A; Bose, S; Evron, E; Gal-Yam, EN; Israeli, S; Kaufman, B; Rubinek, T; Shulman, M; Wolf, I; Zundelevich, A1
Artemov, D; Carraway, H; Domek, J; Kato, Y; Kimble, B; Kowalski, J; Lisok, A; Raman, V; van der Groep, P; van Diest, P; Vesuna, F1
Barekati, Z; Bitzer, J; Grussenmeyer, T; Hartmann, N; Jenoe, P; Kohler, C; Lefkovits, I; Letzkus, M; Moes, S; Radpour, R; Schumacher, MM; Staedtler, F; Zhong, XY1
Gao, W; Singh, KP; Treas, J; Tyagi, T1
Cavalli, LR; da Costa Prando, E; Rainho, CA1
Kucerova, L; Matuskova, M; Poturnajova, M; Tyciakova, S1
Ahuja, N; Baylin, SB; Beaty, R; Brock, MV; Cai, Y; Feller-Kopman, D; Harbom, KM; Harris, J; Issa, JP; Jang, YY; Li, H; Lin, YC; Matsui, W; Minn, I; Pappou, E; Rassool, FV; Robert, C; Sharkis, SJ; Shin, JJ; Stearns, V; Tsai, HC; Van Neste, L; Welm, AL; Yarmus, LB; Yen, RW; Zahnow, CA1
Chen, H; Jin, F; Liu, C; Mao, XY; Wang, H; Wei, J; Yao, F; Zheng, HC1
Ernberg, I; Grigorieva, EV; Gubanova, NV; Haraldson, K; Kashuba, VI; Kharchenko, OA; Kondratov, AG; Kutsenko, OS; Mostovich, LA; Prudnikova, TY; Vavilov, PV; Zabarovsky, ER1
Dutkowski, C; Farrow, L; Fiegl, H; Gee, JM; McClelland, RA; McCloy, RA; Musgrove, EA; Nicholson, RI; Stone, A; Sutherland, RL; Valdés-Mora, F1
Labhasetwar, V; Lu, S; Peetla, C; Vijayaraghavalu, S1
Colon-Otero, G; Cooper, SJ; Copland, JA; Grebe, SK; Kang, KH; Marlow, LA; Menefee, ME; Perez, EA; Tun, HW; von Roemeling, CA1
Dahlman-Wright, K; Gustafsson, JÅ; Putnik, M; Zhao, C1
Atadja, P; Feng, X; Ganapathy, A; Kumar Mishra, M; Morris, D; Qiao Shi, Z; Riabowol, K; Thakur, S1
Chen, Y; Dai, F; Li, G; Li, R; Pan, X; Wang, L; Yang, J; Zhang, Y1
Abe, E; Clyne, CD; Knower, KC; Miki, Y; Sasano, H; Simpson, ER; Suzuki, K; Takagi, K; To, SQ; Yang, Y1
Godwin, AK; Guo, S; Liu, M1
Bogachek, M; Cyr, AR; Domann, FE; Kulak, MV; Li, T; Price, DH; Spanheimer, PM; Weigel, RJ; Woodfield, GW1
Chae, H; Evans, J; Gray, JW; Gu, F; Huang, RL; Huang, TM; Huang, YW; Kim, S; Lai, HC; Lin, H; Liu, Y; Miller, D; Nephew, KP; Pilrose, J; Rao, X; Rhee, JK; Yan, P1
Baraty, C; Bianco, C; Castro, NP; Gonzales, M; Held, N; Karasawa, H; Rangel, MC; Rollman, K; Salomon, DS; Strizzi, L1
Cheriyath, V; Dermawan, JK; Labhasetwar, V; Vijayaraghavalu, S1
Ball, GR; Ellis, IO; Gritzapis, AD; Hughes, DC; Laversin, SA; Li, G; McArdle, SE; Miles, AK; Missitzis, I; Phatak, VM; Powe, DG; Rees, RC1
Labhasetwar, V; Vijayaraghavalu, S1
Chen, H; Hardy, TM; Li, Y; Meeran, SM; Patel, SN; Tollefsbol, TO1
Gagnon, J; Momparler, RL; Primeau, M1
Godwin, AK; Gupta, A; Liu, J; Lu, A; Vanderveer, L1
Gagnon, J; Hurtubise, A; Momparler, RL; Primeau, M; Shaker, S1
Durkin, ME; Popescu, NC; Yuan, BZ1
Acuña, C; Chavez, A; Dueñas-Gonzalez, A; Lizano, M; Mariscal, I; Perez-Cardenas, E; Salazar, AM; Segura-Pacheco, B; Taja-Chayeb, L; Trejo-Becerril, C1
Domann, FE; Futscher, BW; Junk, DJ; Munoz-Rodriguez, JL; Oshiro, MM; Watts, GS; Wozniak, RJ1
Bates, PA; Brown, I; Contreras-Moreira, B; Gabra, H; Li, L; Massie, CE; Miller, EP; Miller, J; Rabiasz, GJ; Scott, D; Sellar, GC; Smyth, JF; Stronach, EA; Watt, KP; Williams, AR1
Andreeff, M; Bast, RC; Fujii, S; Hu, W; Issa, JP; Kadota, M; Luo, RZ; Oshimura, M; Pan, Y; Sahin, AA; Wang, L; Yu, Y; Yuan, J1
Facchinetti, F; Mezzanzanica, D; Modena, P; Pilotti, S; Radice, MT; Sozzi, G; Testi, MA1
Baylin, SB; Belinsky, SA; Crume, KP; Esteller, M; Grimes, MJ; Joste, N; Palmisano, WA; Toyota, M; Winters, SA1
Euhus, DM; Gazdar, AF; Heda, S; Lewis, C; Minna, JD; Rathi, A; Roth, JA; Sugio, K; Takahashi, T; Tonk, V; Virmani, A1
Bell, SM; Carder, PJ; Hanby, AM; Horgan, K; Lane, S; Lansdown, MR; Markham, AF; Munot, K; Parkes, AT; Skliris, GP; Speirs, V1
Davidson, NE; Keen, JC; Mack, KM; Pettit, C; Sharma, D; Smith, D; Yan, L1
Erson, AE; Petty, EM1
David, GL; De Marzo, AM; Kumar, A; Lin, X; Marchi, VL; Nelson, WG; Yegnasubramanian, S1
Hurtubise, A; Momparler, RL2
Doihara, H; Dote, H; Shimizu, N; Teramoto, A; Toyooka, S; Tsukuda, K; Yano, M1
Butcher, DT; Haines, TR; Rodenhiser, DI; Sadikovic, B1
Sharma, D; Vertino, PM1
Dai, JL; Liu, H; Sahin, A; Yuan, Y1
Chen, JX; Cui, XY; Fu, PF; Wang, T1
Davidson, NE; Garrett-Mayer, E; Herman, JG; Keen, JC; Mack, KM; Manning, J; Pettit, C1
Arnold, W; Deutschmann, N; Klebig, C; Pacyna-Gengelbach, M; Petersen, I; Scherneck, S; Seitz, S1
Guo, Y; Huper, G; Marks, JR; Murphy, SK; Olson, JA; Wang, W1
Beaulieu, N; Blum, J; Davidson, NE; Macleod, AR; Sharma, D; Yang, X1
Gudas, LJ; Mongan, NP1
Antsaklis, AI; Baxevanis, CN; Gritzapis, AD; Ioannidis, P; Kavalakis, GJ; Mahaira, LG; Papamichail, M; Perez, SA; Sotiropoulou, PA1
Bakin, AV; Li, X; Quan, L; Safina, AF; Sossey-Alaoui, K; Stourman, NV; Varga, AE; Zheng, Q1
Albergaria, A; Jerónimo, C; Milanezi, F; Oliveira, JT; Paredes, J; Schmitt, FC1
Raut, CG; Somasundaram, K; Wajapeyee, N1
Chan, TK; Chan, V; Cheng, CK; Chow, LW; Loo, WT1
Das, S; Dignam, J; Fackenthal, J; Grushko, TA; Hagos, F; Nanda, R; Olopade, OI; Sveen, L; Tretiakova, M; Wei, M; Xu, J1
DeWille, JW; Sivko, GS; Tang, D1
Argani, P; D'Costa, A; Fackler, MJ; Garrett-Mayer, E; Lo, PK; Mehrotra, J; Sukumar, S1
Jiang, J; Peng, ZH; Tang, B1
Banwell, CM; Campbell, MJ; Colston, KW; Guy, M; MacCartney, DP; Mansi, J; Miles, AE; O'Neill, LP; Stewart, PM; Turner, BM; Uskokovic, MR1
Amberger, A; Eichmann, C; Fiegl, H; Fong, D; Gastl, G; Grünewald, K; Haun, M; Margreiter, R; Millinger, S; Obrist, P; Parson, W; Spizzo, G1
Berenguer, J; Borczuk, AC; Hei, TK; Powell, CA; Shao, G; Zhao, Y1
Davidson, NE; Saxena, NK; Sharma, D; Vertino, PM1
Pampalakis, G; Sotiropoulou, G1
Diamandis, EP; Pampalakis, G; Sotiropoulou, G1
Bhalla, KN; Huang, C; Inoue, M; Ito, K; Ito, Y; Ko, TK; Lau, QC; Liu, Q; Loh, M; Putti, TC; Raja, E; Salto-Tellez, M; Sukumar, S; Zhu, T1
Hongmei, L; Xiaoyan, X; Yuecheng, Y1
Coleman, WB; Jones, WD; Rivenbark, AG1
Fabianowska-Majewska, K; Krawczyk, B1
Calin, GA; Croce, CM; Di Leva, G; Godwin, AK; Iliopoulos, D; Negrini, M; Nicoloso, MS; Petrocca, F; Qin, HR; Shimizu, M; Trapasso, F; Vecchione, A; Wojcik, SE; Yendamuri, S1
Euhus, DM; Fong, KM; Gao, B; Gazdar, AF; Gerald, W; Girard, L; Jiang, A; Kim, YH; Lam, CL; Lewis, CM; Minna, JD; Nanda, R; Olopade, OI; Perou, CM; Pollack, JR; Sato, M; Shames, DS; Shay, JW; Shivapurkar, N; Shyr, Y; Wong, M1
Fujisawa, T; Gazdar, AF; Iizasa, T; Minna, JD; Shames, DS; Shigematsu, H; Shivapurkar, N; Sunaga, N; Suzuki, M; Takahashi, T1
Druck, T; Fabbri, M; Han, SY; Huebner, K; Iliopoulos, D; Qin, HR1
Berger, W; Depisch, D; Filipits, M; Geradts, J; Heller, G; Kandioler, D; Markis-Ritzinger, EM; Newsham, I; Pirker, R; Stiglbauer, W; Ziegler, B; Zielinski, CC; Zöchbauer-Müller, S1
Tainsky, MA; Wu, GS; Xu, J; Zhou, JY1
Díaz-Montero, CM; Estecio, M; Issa, JP; Mao, L; Montero, AJ; Shen, L; Youssef, EM1
Betz, B; Ehrentraut, D; Felsberg, J; Hampl, JA; Hellmich, M; Köhler, J; Mikeska, T; Niederacher, D; Pietsch, T; Röhn, G; Schmutzler, RK; Versmold, B; Waha, A1
Di, GH; Fan, J; Hou, YF; Lei, W; Li, DQ; Lu, JS; Shao, ZM; Shen, ZZ; Wu, FY; Wu, J; Yin, WJ1
Fan, QX; Li, LW; Lu, SH; Wang, LX; Wang, R; Wang, RL; Zhao, PR1
Bronner, C; Giordano, A; Gregorio, V; Macaluso, M; Montanari, M; Noto, PB1
Keen, JC; Obajimi, O; Pryzbylkowski, P1
Christgen, M; Hasemeier, B; Kreipe, H; Länger, F; Lehmann, U; Müller, M; Römermann, D1
Fabianowska-Majewska, K; Krawczyk, B; Rudnicka, K1
Chen, J; Huang, T; Liu, K; Wang, G; Zhang, B1
Coleman, WB; Jones, WD; Rivenbark, AG; Roll, JD1
Di, GH; Fan, J; Lu, JS; Shao, ZM; Shen, ZZ; Wang, L; Wu, FY; Wu, J; Yin, WJ1
Ethier, SP; Hanifi-Moghaddam, P; Hollestelle, A; Klijn, JG; Merajver, SD; Schutte, M; van den Ouweland, A; Wasielewski, M1
Hancock, MC; Smith, HS1
Dekker, A; Dorssers, LC; Foekens, JA; van Agthoven, T; van Agthoven, TL1
Baylin, SB; Davidson, NE; Ferguson, AT; Lapidus, RG1
Dorssers, LC; Foekens, JA; van Agthoven, T; van Agthoven, TL1
Alpert, L; Huynh, H; Pollak, M1
Akiyoshi, T; Fujie, T; Mori, M; Sugimachi, K; Ueo, H1
Fearon, ER; Ji, X; Rimm, DL; Woodard, AS1
Baylin, SB; Davidson, NE; Ferguson, AT; Muller, MT; Spitzner, JR; Vertino, PM1
Jhaveri, MS; Morrow, CS1
Ammanamanchi, S; Brattain, MG; Kim, SJ; Sun, LZ1
Rabbani, SA; Xing, RH1
Bovenzi, V; Côte, S; Lê, NL; Momparler, LF; Momparler, RL; Sinnett, D1
Ferguson, AT; Orlandi, R; Sacchi, N; Sirchia, SM; Sironi, E; Subramanyan, S; Sukumar, S1
Chan, TA; Evron, E; Ferguson, AT; Futreal, PA; Hermeking, H; Lambers, AR; Marks, JR; Pandita, TK; Stampfer, MR; Sukumar, S; Umbricht, CB1
Benchaïb, M; Billard, LM; Dante, R; Frappart, L; Guérin, JF; Lenoir, GM; Magdinier, F; Wittmann, G1
Arapshian, A; Kuppumbatti, YS; Mira-y-Lopez, R1
Ammanamanchi, S; Brattain, MG; Periyasamy, S; Tillekeratne, MP1
Kakudo, K; Mori, I; Nakamura, M; Nakamura, Y; Sakurai, T; Shan, L; Suzuma, T; Tamaki, T; Umemura, T; Utsunomiya, H; Yang, Q; Yoshimura, G1
Clare, SE; Clark, G; Elkahloun, AG; Hartsough, MT; Mair, M; Osborne, CK; Sgroi, D; Steeg, PS1
Ashfaq, R; Fong, KM; Gazdar, AF; Geradts, J; Lam, S; Maitra, A; Milchgrub, S; Minna, JD; Virmani, AK; Zöchbauer-Müller, S1
Ammanamanchi, S; Brattain, MG1
Bovenzi, V; Momparler, RL1
Dzhandzhugazyan, KN; Guldberg, P; Kirkin, AF; Worm, J1
Ahlborn, TE; Gupta, A; Li, C; Liu, J; Lu, A; Ma, Y; Shi, EY1
Davidson, NE; Ferguson, AT; Herman, JG; Nelson, WG; Phillips, DL; Yang, X1
Band, V; Dhar, S; Dimri, G; Evron, E; Goyal, J; Li, B; Sukumar, S; Wazer, DE1
Filmus, J; Ladeda, V; Xiang, YY1
Crichton, DN; Hupp, TR; Kernohan, N; McDowell, HE; Nicoll, G; Thompson, AM1
Bianco, T; Dobrovic, A; Tan, LW1
Bharadwaj, S; Prasad, GL1
Dallol, A; Forgacs, E; Kishida, T; Latif, F; Maher, ER; Martinez, A; Minna, JD; Rabbitts, P; Sekido, Y; Walker, R1
Muggia, FM; Slavik, M; Von Hoff, DD1
Keyomarsi, K; Lee, SW; Sager, R; Swisshelm, K; Tomasetto, C1
Esparza, L; Holmes, FA; Hortobagyi, GN; Theriault, RL; Walters, RS1
Carroll, AR; Kahl, LP; Read, NG; Rhodes, P; Wood, J1
Golovkina, TV; Litvinov, SV1
Gregory, P; Wang, N1
Kaysen, J; Kufe, D; Spriggs, D1
Bruntsch, U; Gallmeier, WM; Osieka, R; Schmidt, CG; Seeber, S1

Reviews

5 review(s) available for azacitidine and Breast Cancer

ArticleYear
Combination treatment with CPX-351 and midostaurin in patients with secondary acute myeloid leukaemia that are FLT3 mutated: three cases and review of literature.
    British journal of haematology, 2020, Volume: 190, Issue:3

    Topics: Aged; Allografts; Anemia, Refractory, with Excess of Blasts; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials, Phase III as Topic; Cytarabine; Daunorubicin; Fatal Outcome; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm, Residual; Neoplasms, Radiation-Induced; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Point Mutation; Protein Kinase Inhibitors; Pyrazines; Remission Induction; Salvage Therapy; Staurosporine; Sulfonamides

2020
Conviction in the face of affliction: a case series of Jehovah's Witnesses with myeloid malignancies.
    Annals of hematology, 2018, Volume: 97, Issue:11

    Topics: Aged; Anemia, Macrocytic; Antimetabolites, Antineoplastic; Arthritis, Rheumatoid; Azacitidine; Blood Transfusion; Breast Neoplasms; Female; Humans; Hydroxyurea; Isocitrate Dehydrogenase; Jehovah's Witnesses; Leukemia, Myeloid, Acute; Male; Myeloproliferative Disorders; Neoplasms, Second Primary; Treatment Refusal

2018
Bone marrow stromal antigen 2 (BST-2) DNA is demethylated in breast tumors and breast cancer cells.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Antigens, CD; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Computational Biology; CpG Islands; Databases, Nucleic Acid; DNA Methylation; Epigenomics; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Promoter Regions, Genetic; RNA, Messenger

2015
A Comparative Study on the In Vitro Effects of the DNA Methyltransferase Inhibitor 5-Azacytidine (5-AzaC) in Breast/Mammary Cancer of Different Mammalian Species.
    Journal of mammary gland biology and neoplasia, 2016, Volume: 21, Issue:1-2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Breast Neoplasms; Cats; Cell Line; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Animal; Neoplasm Proteins; Promoter Regions, Genetic; Proof of Concept Study; Species Specificity; Tumor Cells, Cultured

2016
5-Azacytidine. A new anticancer drug with effectiveness in acute myelogenous leukemia.
    Annals of internal medicine, 1976, Volume: 85, Issue:2

    Topics: Animals; Azacitidine; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Europe; Female; Humans; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Liver; Nausea; Neoplasms, Experimental; Neuromuscular Diseases; RNA, Messenger; United States; Vomiting

1976

Trials

1 trial(s) available for azacitidine and Breast Cancer

ArticleYear
Phase II trial of fazarabine (ARA-AC, arabinosyl-5-azacytosine) in metastatic breast cancer.
    Investigational new drugs, 1992, Volume: 10, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Azacitidine; Breast Neoplasms; Carcinoma; Drug Evaluation; Female; Humans; Middle Aged

1992

Other Studies

242 other study(ies) available for azacitidine and Breast Cancer

ArticleYear
Induced Tamoxifen Resistance is Mediated by Increased Methylation of E-Cadherin in Estrogen Receptor-Expressing Breast Cancer Cells.
    Scientific reports, 2019, Oct-02, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Breast Neoplasms; Cadherins; Cell Movement; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Nuclear Proteins; Receptors, Estrogen; Tamoxifen; Twist-Related Protein 1

2019
The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer.
    BMC immunology, 2020, 02-27, Volume: 21, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; DNA Modification Methylases; Female; Humans; Immunotherapy, Adoptive; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells; Myelopoiesis; T-Lymphocytes, Cytotoxic

2020
5-Aza-2'-deoxycytidine advances the epithelial-mesenchymal transition of breast cancer cells by demethylating
    Journal of cell science, 2020, 05-11, Volume: 133, Issue:9

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans

2020
SHISA3, an antagonist of the Wnt/β-catenin signaling, is epigenetically silenced and its ectopic expression suppresses growth in breast cancer.
    PloS one, 2020, Volume: 15, Issue:7

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; RNA, Messenger; Wnt Signaling Pathway

2020
Long-term exposure to estrogen enhances chemotherapeutic efficacy potentially through epigenetic mechanism in human breast cancer cells.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Decitabine; DNA Methylation; Doxorubicin; Drug Synergism; Epigenesis, Genetic; Estradiol; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; MCF-7 Cells

2017
Azacytidine-induced Chemosensitivity to Doxorubicin in Human Breast Cancer MCF7 Cells.
    Anticancer research, 2017, Volume: 37, Issue:5

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Azacitidine; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Proliferation; Cell Survival; Doxorubicin; Female; Humans; MCF-7 Cells; Mitogen-Activated Protein Kinases; NF-kappa B; Reactive Oxygen Species; Tumor Suppressor Protein p53

2017
HLJ1 (DNAJB4) Gene Is a Novel Biomarker Candidate in Breast Cancer.
    Omics : a journal of integrative biology, 2017, Volume: 21, Issue:5

    Topics: Adult; Azacitidine; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cohort Studies; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; HSP40 Heat-Shock Proteins; Humans; Hydroxamic Acids; Kaplan-Meier Estimate; Precision Medicine; RNA, Messenger

2017
Demethylation of miR-495 inhibits cell proliferation, migration and promotes apoptosis by targeting STAT-3 in breast cancer.
    Oncology reports, 2017, Volume: 37, Issue:6

    Topics: Apoptosis; Azacitidine; Breast Neoplasms; Cell Movement; Cell Proliferation; Demethylation; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs; Promoter Regions, Genetic; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A

2017
MMP9 gene expression regulation by intragenic epigenetic modifications in breast cancer.
    Gene, 2018, Feb-05, Volume: 642

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 9; MCF-7 Cells; Neoplasm Metastasis; Promoter Regions, Genetic; Sequence Analysis, DNA

2018
DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer.
    Nature communications, 2018, 01-16, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, MHC Class I; Humans; Mammary Neoplasms, Experimental; Mice; Promoter Regions, Genetic; T-Lymphocytes, Cytotoxic

2018
Culturing conditions highly affect DNA methylation and gene expression levels in MCF7 breast cancer cell line.
    In vitro cellular & developmental biology. Animal, 2018, Volume: 54, Issue:5

    Topics: Azacitidine; Breast Neoplasms; Cell Culture Techniques; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoplasm Proteins; Promoter Regions, Genetic

2018
Differential expression of IL-6/IL-6R and MAO-A regulates invasion/angiogenesis in breast cancer.
    British journal of cancer, 2018, Volume: 118, Issue:11

    Topics: Animals; Antigens, CD; Azacitidine; Breast Neoplasms; Cadherins; Cell Hypoxia; Cell Line, Tumor; Chick Embryo; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-6; Models, Biological; Monoamine Oxidase; Neoplasm Invasiveness; Receptors, Interleukin-6; Vascular Endothelial Growth Factor A

2018
The overexpression of hypomethylated miR-663 induces chemotherapy resistance in human breast cancer cells by targeting heparin sulfate proteoglycan 2 (HSPG2).
    The Journal of biological chemistry, 2013, Apr-19, Volume: 288, Issue:16

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cyclophosphamide; Decitabine; DNA Methylation; DNA, Neoplasm; Docetaxel; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Heparan Sulfate Proteoglycans; Humans; Methylation; MicroRNAs; Neoplasm Proteins; RNA, Neoplasm; Taxoids

2013
Lactate dehydrogenase-B is silenced by promoter methylation in a high frequency of human breast cancers.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Carcinoma, Ductal; Case-Control Studies; Cell Line, Tumor; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Glycolysis; Humans; Hypoxia; Isoenzymes; L-Lactate Dehydrogenase; Middle Aged; Neoplasm Proteins; Promoter Regions, Genetic; Sequence Analysis, DNA

2013
Epigenetic control of endothelin-1 axis affects invasiveness of breast carcinoma cells with bone tropism.
    Experimental cell research, 2013, Jul-15, Volume: 319, Issue:12

    Topics: Azacitidine; Bone Neoplasms; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Movement; Collagen; Dactinomycin; DNA Methylation; Drug Combinations; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Laminin; Mutation; Neoplasm Invasiveness; Peptides, Cyclic; Proteoglycans; Proto-Oncogene Protein c-ets-1; Receptor, Endothelin A; RNA Stability; RNA, Messenger; Transcription, Genetic

2013
Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance.
    Cancer letters, 2013, Sep-01, Volume: 337, Issue:2

    Topics: Active Transport, Cell Nucleus; Antineoplastic Agents, Hormonal; Apoptosis; Azacitidine; Breast Neoplasms; Cell Survival; Chromatin Assembly and Disassembly; Decitabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; MCF-7 Cells; Tamoxifen; Time Factors; Transfection

2013
Insulin-like growth factor binding protein-3 (IGFBP-3) plays a role in the anti-tumorigenic effects of 5-Aza-2'-deoxycytidine (AZA) in breast cancer cells.
    Experimental cell research, 2013, Aug-15, Volume: 319, Issue:14

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Death; Cell Proliferation; Cell Transformation, Neoplastic; Decitabine; DNA Methylation; Epigenesis, Genetic; Estrogen Receptor alpha; Female; Gene Silencing; Humans; Insulin-Like Growth Factor Binding Protein 3; MCF-7 Cells; RNA, Small Interfering; Transcription Factor AP-2; Tumor Suppressor Protein p53

2013
Laccaic acid A is a direct, DNA-competitive inhibitor of DNA methyltransferase 1.
    The Journal of biological chemistry, 2013, Aug-16, Volume: 288, Issue:33

    Topics: Aminoquinolines; Anthraquinones; Azacitidine; Azo Compounds; Base Sequence; Breast Neoplasms; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Replication; Enzyme Inhibitors; Female; Fluorometry; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Pyrimidines; Reproducibility of Results; Signal Transduction; Transition Temperature

2013
Activation-induced cytidine deaminase (AID) is necessary for the epithelial-mesenchymal transition in mammary epithelial cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Aug-06, Volume: 110, Issue:32

    Topics: Animals; Azacitidine; Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Movement; CpG Islands; Cytidine Deaminase; Decitabine; DNA Methylation; Epithelial Cells; Epithelial-Mesenchymal Transition; Gene Expression Regulation; Genetic Complementation Test; HEK293 Cells; Humans; Mammary Glands, Human; Matrix Metalloproteinases; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2013
Aberrant NDRG1 methylation associated with its decreased expression and clinicopathological significance in breast cancer.
    Journal of biomedical science, 2013, Jul-30, Volume: 20

    Topics: Azacitidine; Breast Neoplasms; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Neoplasm Metastasis; Promoter Regions, Genetic

2013
Epigenetic modifications of prostate-derived Ets transcription factor in breast cancer cells.
    Oncology reports, 2013, Volume: 30, Issue:4

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; DNA Methylation; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Humans; Male; MCF-7 Cells; Prostatic Neoplasms; Proto-Oncogene Proteins c-ets

2013
Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis.
    Breast cancer research : BCR, 2013, Aug-23, Volume: 15, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Promoter Regions, Genetic; Protein Kinase C; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Array Analysis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2013
Synergistic anti-breast cancer effect of a combined treatment with the methyl donor S-adenosyl methionine and the DNA methylation inhibitor 5-aza-2'-deoxycytidine.
    Carcinogenesis, 2014, Volume: 35, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Matrix Metalloproteinase 2; MCF-7 Cells; S-Adenosylmethionine; Urokinase-Type Plasminogen Activator

2014
Regulation of estrogen receptor β1 expression in breast cancer by epigenetic modification of the 5' regulatory region.
    International journal of oncology, 2013, Volume: 43, Issue:6

    Topics: 5' Untranslated Regions; Acetylation; Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Loss of Heterozygosity; Promoter Regions, Genetic; RNA, Messenger

2013
Tumor suppressive function of mir-205 in breast cancer is linked to HMGB3 regulation.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: 3' Untranslated Regions; Azacitidine; Base Pairing; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin; Epithelial-Mesenchymal Transition; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HMGB3 Protein; Humans; MicroRNAs; Neoplasm Invasiveness; Repressor Proteins; Tumor Suppressor Proteins

2013
Down-regulation of tripartite-motif containing 22 expression in breast cancer is associated with a lack of p53-mediated induction.
    Biochemical and biophysical research communications, 2013, Nov-22, Volume: 441, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Camptothecin; DNA Damage; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; MCF-7 Cells; Minor Histocompatibility Antigens; Paclitaxel; Promoter Regions, Genetic; Repressor Proteins; Topoisomerase I Inhibitors; Tripartite Motif Proteins; Tubulin Modulators; Tumor Suppressor Protein p53

2013
High-density array analysis of DNA methylation in Tamoxifen-resistant breast cancer cell lines.
    Epigenetics, 2014, Volume: 9, Issue:2

    Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; DNA Methylation; Drug Resistance, Neoplasm; Estrogen Antagonists; Estrogen Receptor alpha; Female; Humans; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Repressor Proteins; Tamoxifen

2014
Circumvention of drug-resistance via decitabine-mediated DNMT1 depletion.
    Epigenomics, 2013, Volume: 5, Issue:3

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Polyethylene Glycols; Polyethyleneimine

2013
Expressions of MAGE-A9 and MAGE-A11 in breast cancer and their expression mechanism.
    Archives of medical research, 2014, Volume: 45, Issue:1

    Topics: Adult; Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Modification Methylases; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Middle Aged; Neoplasm Proteins; Receptors, Estrogen

2014
Methylation and miRNA effects of resveratrol on mammary tumors vs. normal tissue.
    Nutrition and cancer, 2014, Volume: 66, Issue:2

    Topics: Animals; Azacitidine; Breast; Breast Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Down-Regulation; Estrogens; Female; MicroRNAs; Rats; Rats, Inbred ACI; Resveratrol; Stilbenes

2014
Small activating RNA restores the activity of the tumor suppressor HIC-1 on breast cancer.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adult; Apoptosis; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kruppel-Like Transcription Factors; Oligonucleotide Array Sequence Analysis; RNA; Tissue Array Analysis; Transcriptome; Up-Regulation

2014
Secreted phospholipases A₂are differentially expressed and epigenetically silenced in human breast cancer cells.
    Biochemical and biophysical research communications, 2014, Feb-28, Volume: 445, Issue:1

    Topics: Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Group II Phospholipases A2; Group III Phospholipases A2; Group X Phospholipases A2; Humans; Hydroxamic Acids; MCF-7 Cells; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction

2014
A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells.
    Breast cancer research and treatment, 2014, Volume: 144, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Nude; Neoplasm Invasiveness; Phthalimides; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Tryptophan; Xenograft Model Antitumor Assays

2014
5-Aza-2-deoxycytidine and trichostatin A increase COUP-TFII expression in antiestrogen-resistant breast cancer cell lines.
    Cancer letters, 2014, May-28, Volume: 347, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; COUP Transcription Factor II; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Humans; Hydroxamic Acids; MCF-7 Cells; Real-Time Polymerase Chain Reaction

2014
DNA methylation of heparanase promoter influences its expression and associated with the progression of human breast cancer.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Carcinogenesis; Cell Proliferation; Decitabine; Disease Progression; DNA Methylation; Gene Expression Regulation, Neoplastic; Glucuronidase; Humans; MCF-7 Cells; Neoplasm Invasiveness; Promoter Regions, Genetic

2014
5-azacytidine induces anoikis, inhibits mammosphere formation and reduces metalloproteinase 9 activity in MCF-7 human breast cancer cells.
    Molecules (Basel, Switzerland), 2014, Mar-13, Volume: 19, Issue:3

    Topics: Anoikis; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Female; Humans; Matrix Metalloproteinase 9; MCF-7 Cells; Spheroids, Cellular; Tumor Cells, Cultured

2014
Breast cancer cells are arrested at different phases of the cell cycle following the re-expression of ARHI.
    Oncology reports, 2014, Volume: 31, Issue:5

    Topics: Apoptosis; Azacitidine; Breast Neoplasms; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Cyclin B1; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Decitabine; Female; G2 Phase Cell Cycle Checkpoints; Genetic Vectors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Methyltransferases; Protein Kinases; rho GTP-Binding Proteins; RNA Interference; RNA, Small Interfering; S Phase Cell Cycle Checkpoints; Transfection; Tumor Suppressor Protein p53

2014
The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines.
    Breast cancer research and treatment, 2014, Volume: 145, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA; DNA Methylation; Epigenesis, Genetic; Female; Histones; Humans; Hydroxamic Acids; MCF-7 Cells; Methyltransferases; Promoter Regions, Genetic; Shelterin Complex; Telomere; Telomere Homeostasis; Telomere-Binding Proteins

2014
Aberrant promoter DNA methylation inhibits bone morphogenetic protein 2 expression and contributes to drug resistance in breast cancer.
    Molecular medicine reports, 2014, Volume: 10, Issue:2

    Topics: Azacitidine; Bone Morphogenetic Protein 2; Breast Neoplasms; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; MCF-7 Cells; Neoplasm Staging; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering

2014
Lidocaine and ropivacaine, but not bupivacaine, demethylate deoxyribonucleic acid in breast cancer cells in vitro.
    British journal of anaesthesia, 2014, Volume: 113 Suppl 1

    Topics: Amides; Anesthetics, Local; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Bupivacaine; Cell Survival; Decitabine; DNA Methylation; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Epigenesis, Genetic; Female; Humans; Lidocaine; MCF-7 Cells; Ropivacaine; Tumor Cells, Cultured

2014
Glycerol-3-phosphate acyltranferase-2 behaves as a cancer testis gene and promotes growth and tumorigenicity of the breast cancer MDA-MB-231 cell line.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Azacitidine; Breast Neoplasms; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Computer Simulation; Decitabine; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Glycerol-3-Phosphate O-Acyltransferase; Humans; Male; Mice; RNA, Small Interfering; Testis

2014
Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines.
    Theoretical biology & medical modelling, 2014, May-07, Volume: 11 Suppl 1

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; Down-Regulation; Epigenesis, Genetic; Female; Gene Regulatory Networks; Genes, Neoplasm; Humans; Melanoma; Signal Transduction; Transcription, Genetic; Up-Regulation

2014
Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness.
    Carcinogenesis, 2014, Volume: 35, Issue:11

    Topics: Azacitidine; Breast Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Molecular Targeted Therapy; Neoplasm Invasiveness; Promoter Regions, Genetic

2014
Fibronectin affects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Azacitidine; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Molecular Sequence Data; Neoplasm Invasiveness; Promoter Regions, Genetic; Time Factors; Transcriptional Activation

2014
Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.
    Breast cancer research : BCR, 2014, Sep-24, Volume: 16, Issue:5

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; Humans; Kaplan-Meier Estimate; Promoter Regions, Genetic; Proto-Oncogene Proteins c-vav

2014
A novel tumor suppressor function of Kindlin-3 in solid cancer.
    Oncotarget, 2014, Oct-15, Volume: 5, Issue:19

    Topics: Animals; Azacitidine; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Heterografts; Humans; Integrin beta3; Melanoma; Membrane Proteins; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Phosphorylation; RNA Interference; RNA, Messenger; RNA, Small Interfering; Talin

2014
Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
    Oncology reports, 2015, Volume: 33, Issue:1

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Mammary Glands, Human; Organ Specificity; Promoter Regions, Genetic; Serine Proteases

2015
Combination therapy with epigenetic-targeted and chemotherapeutic drugs delivered by nanoparticles to enhance the chemotherapy response and overcome resistance by breast cancer stem cells.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, May-10, Volume: 205

    Topics: Aldehyde Dehydrogenase; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Breast Neoplasms; Caspase 9; Cell Line, Tumor; Chemistry, Pharmaceutical; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Dose-Response Relationship, Drug; Doxorubicin; Drug Carriers; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Mice, Inbred NOD; Mice, SCID; Nanomedicine; Nanoparticles; Neoplastic Stem Cells; Polyesters; Polyethylene Glycols; Spheroids, Cellular; Technology, Pharmaceutical; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2015
MiR-335 inhibits migration of breast cancer cells through targeting oncoprotein c-Met.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:4

    Topics: Azacitidine; Breast Neoplasms; Cell Movement; Cell Proliferation; Decitabine; Female; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; MCF-7 Cells; MicroRNAs; Neoplasm Invasiveness; Proto-Oncogene Proteins c-met

2015
The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition.
    Nucleic acids research, 2015, Volume: 43, Issue:1

    Topics: Antigens, CD; Azacitidine; Breast Neoplasms; Cadherins; CCCTC-Binding Factor; Cell Line, Tumor; Cell Movement; Cells, Cultured; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epithelial-Mesenchymal Transition; Female; Gene Silencing; HMGA2 Protein; Humans; Promoter Regions, Genetic; Repressor Proteins; Transforming Growth Factor beta

2015
Potentiation of growth inhibition and epigenetic modulation by combination of green tea polyphenol and 5-aza-2'-deoxycytidine in human breast cancer cells.
    Breast cancer research and treatment, 2015, Volume: 149, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Catechin; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; MCF-7 Cells; Plant Extracts; Random Amplified Polymorphic DNA Technique; Tea

2015
miR-491-5p functions as a tumor suppressor by targeting JMJD2B in ERα-positive breast cancer.
    FEBS letters, 2015, Mar-24, Volume: 589, Issue:7

    Topics: 3' Untranslated Regions; Adult; Aged; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Jumonji Domain-Containing Histone Demethylases; MCF-7 Cells; MicroRNAs; Middle Aged

2015
Elevation of soluble guanylate cyclase suppresses proliferation and survival of human breast cancer cells.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Animals; Apoptosis; Azacitidine; Bradykinin; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cell Survival; Cyclic GMP; Decitabine; DNA Methylation; Female; Guanylate Cyclase; Humans; MCF-7 Cells; Mice; Mice, Nude; Nitric Oxide; Nitroprusside; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase

2015
Loss of response to azacitidine is associated with deletion 12p13 in a patient with myelodysplastic syndrome with unique translocation t(13;17)(q12;q25) after prior breast cancer and acute promyelocytic leukemia.
    Annals of hematology, 2015, Volume: 94, Issue:9

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 13; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Translocation, Genetic

2015
Lack of ADAM2, CALR3 and SAGE1 Cancer/Testis Antigen Expression in Lung and Breast Cancer.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: ADAM Proteins; Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Calreticulin; Cell Line, Tumor; Cohort Studies; Female; Fertilins; Humans; Immunohistochemistry; Lung Neoplasms; Melanoma-Specific Antigens; Membrane Glycoproteins

2015
Differential involvement of RASSF2 hypermethylation in breast cancer subtypes and their prognosis.
    Oncotarget, 2015, Sep-15, Volume: 6, Issue:27

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Hydroxamic Acids; Immunohistochemistry; Kaplan-Meier Estimate; Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; Treatment Outcome; Tumor Suppressor Proteins

2015
[Interaction between miR-21 and DNA methylation in different breast cancer cells].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2015, Volume: 31, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Up-Regulation

2015
Treatment with 5-Aza-2'-Deoxycytidine Induces Expression of NY-ESO-1 and Facilitates Cytotoxic T Lymphocyte-Mediated Tumor Cell Killing.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; Female; HLA-A2 Antigen; Humans; Immunotherapy; Interferon-gamma; MCF-7 Cells; Membrane Proteins; Microscopy, Fluorescence; Multiple Myeloma; Peptides; Real-Time Polymerase Chain Reaction; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Up-Regulation

2015
Coordinate regulation of microenvironmental stimuli and role of methylation in bone metastasis from breast carcinoma.
    Biochimica et biophysica acta, 2016, Volume: 1863, Issue:1

    Topics: Animals; Azacitidine; Bone Neoplasms; Breast Neoplasms; DNA Methylation; DNA, Neoplasm; Endothelin-1; Female; Humans; Mice; Mice, Nude; MicroRNAs; Neoplasm Metastasis; Neoplasm Proteins; Osteonectin; RNA, Neoplasm; Tumor Microenvironment

2016
Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer.
    Oncotarget, 2016, Jan-12, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Immunohistochemistry; MCF-7 Cells; Phenylbutyrates; rab GTP-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; Signal Transduction; Trastuzumab; Zinc Finger E-box-Binding Homeobox 1

2016
An Unexpected Innocent Complication Associated with Azacitidine Treatment of Myelodysplastic Syndrome: Erythema Annulare Centrifugum.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2016, Mar-05, Volume: 33, Issue:1

    Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Chemoradiotherapy; Drug Hypersensitivity; Erythema; Fatal Outcome; Female; Humans; Mastectomy, Radical; Sepsis

2016
Effect of 5-azacytidine on miRNA expression in human breast cancer cells with different sensitivity to cytostatics.
    Experimental oncology, 2016, Volume: 38, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Cytostatic Agents; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs

2016
Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: Antineoplastic Agents; Azacitidine; Benzamides; Breast Neoplasms; CpG Islands; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Epigenesis, Genetic; Exons; Female; GPI-Linked Proteins; Histone Deacetylase Inhibitors; Humans; MCF-7 Cells; Methotrexate; Middle Aged; Neoplasm Grading; Neoplasm Staging; Promoter Regions, Genetic; Pyridines; Time Factors

2016
Factors affecting the persistence of drug-induced reprogramming of the cancer methylome.
    Epigenetics, 2016, 04-02, Volume: 11, Issue:4

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cellular Reprogramming; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Promoter Regions, Genetic

2016
Altered methylation of glucosylceramide synthase promoter regulates its expression and associates with acquired multidrug resistance in invasive ductal breast cancer.
    Oncotarget, 2016, Jun-14, Volume: 7, Issue:24

    Topics: Adult; Azacitidine; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Multiple; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Glucosyltransferases; Humans; MCF-7 Cells; Neoplasm Invasiveness; Promoter Regions, Genetic

2016
Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth.
    Cancer research, 2016, 06-01, Volume: 76, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Carcinoma, Basal Cell; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Therapy, Combination; Female; High-Throughput Nucleotide Sequencing; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplastic Stem Cells; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2016
DNA methyltransferase inhibition increases efficacy of adoptive cellular immunotherapy of murine breast cancer.
    Cancer immunology, immunotherapy : CII, 2016, Volume: 65, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Modification Methylases; Enzyme Inhibitors; Female; Humans; Immunotherapy, Adoptive; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; T-Lymphocytes

2016
Decreased expression of EZH2 reactivates RASSF2A by reversal of promoter methylation in breast cancer cells.
    Cell biology international, 2016, Volume: 40, Issue:10

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Breast Neoplasms; Cell Line, Tumor; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Knockdown Techniques; Humans; MCF-7 Cells; Promoter Regions, Genetic; Tumor Suppressor Proteins; Up-Regulation

2016
DNA methylation of claudin-6 promotes breast cancer cell migration and invasion by recruiting MeCP2 and deacetylating H3Ac and H4Ac.
    Journal of experimental & clinical cancer research : CR, 2016, 07-26, Volume: 35, Issue:1

    Topics: Acetylation; Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Claudins; DNA Methylation; Epigenesis, Genetic; Female; Histones; Humans; Hydroxamic Acids; MCF-7 Cells; Methyl-CpG-Binding Protein 2; Middle Aged; Neoplasm Invasiveness; Promoter Regions, Genetic; Young Adult

2016
DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells.
    Oncotarget, 2016, Oct-25, Volume: 7, Issue:43

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Azacitidine; Breast; Breast Neoplasms; Carcinogenesis; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; CpG Islands; Decitabine; DNA Demethylation; DNA Methylation; Down-Regulation; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Glycogen Synthase Kinase 3; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Wnt Signaling Pathway

2016
Epigenetic regulation of HGF/Met receptor axis is critical for the outgrowth of bone metastasis from breast carcinoma.
    Cell death & disease, 2017, 02-02, Volume: 8, Issue:2

    Topics: Animals; Azacitidine; Bone Neoplasms; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Nucleus; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Nuclear Proteins; Proto-Oncogene Proteins c-met; Signal Transduction; Tumor Microenvironment; Tumor Suppressor Proteins

2017
Astrocyte-induced Reelin expression drives proliferation of Her2
    Clinical & experimental metastasis, 2017, Volume: 34, Issue:2

    Topics: Astrocytes; Azacitidine; Brain Neoplasms; Breast Neoplasms; Cell Adhesion Molecules, Neuronal; Cell Division; Coculture Techniques; Culture Media, Serum-Free; DNA Methylation; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Nerve Tissue Proteins; Receptor, ErbB-2; Reelin Protein; RNA Interference; RNA, Small Interfering; Serine Endopeptidases; Spheroids, Cellular; Transcriptional Activation; Triple Negative Breast Neoplasms; Tumor Cells, Cultured

2017
Hyper-methylation of the upstream CpG island shore is a likely mechanism of GPER1 silencing in breast cancer cells.
    Gene, 2017, May-30, Volume: 614

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genetic Variation; Humans; MCF-7 Cells; Receptors, Estrogen; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA

2017
Comparative epigenomics of human and mouse mammary tumors.
    Genes, chromosomes & cancer, 2009, Volume: 48, Issue:1

    Topics: Animals; Azacitidine; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Databases, Genetic; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation; Gene Silencing; Genes, Tumor Suppressor; Glycoproteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Mammary Neoplasms, Animal; Mice; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Structure-Activity Relationship; Tissue Inhibitor of Metalloproteinase-3

2009
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer.
    Biochemical and biophysical research communications, 2008, Dec-12, Volume: 377, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Female; Fructose-Bisphosphatase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Middle Aged; Neoplasms; Promoter Regions, Genetic

2008
Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy.
    Molecular cancer research : MCR, 2009, Volume: 7, Issue:2

    Topics: Azacitidine; Base Sequence; Breast Neoplasms; Cell Line; Cell Movement; Chemotherapy, Adjuvant; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoenzyme Techniques; Lasers; Membrane Microdomains; Membrane Transport Proteins; Middle Aged; Molecular Sequence Data; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Prognosis; Promoter Regions, Genetic; Proteolipids; Reverse Transcriptase Polymerase Chain Reaction; Survival Rate; Wound Healing

2009
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells.
    International journal of cancer, 2009, Jul-15, Volume: 125, Issue:2

    Topics: Amino Acid Oxidoreductases; Azacitidine; Blotting, Western; Breast Neoplasms; Catalysis; Cell Line; Cell Line, Tumor; Decitabine; Gene Expression Regulation, Enzymologic; Humans; Hydroxamic Acids; Immunohistochemistry; Mammary Glands, Human; Neoplasm Metastasis; Reverse Transcriptase Polymerase Chain Reaction

2009
Growth inhibition of human cancer cells by 5-aza-2'-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:4

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Suppressor Protein p14ARF

2009
A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.
    Cancer research, 2009, May-15, Volume: 69, Issue:10

    Topics: Animals; Azacitidine; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Colonic Neoplasms; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Modification Methylases; Female; Gene Silencing; Genes, Tumor Suppressor; HeLa Cells; Humans; Liver Neoplasms; Mice; Quinolines; Reverse Transcriptase Polymerase Chain Reaction

2009
Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells.
    Archives of medical research, 2009, Volume: 40, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Butyrates; Colonic Neoplasms; Decitabine; Enzyme Inhibitors; HT29 Cells; Humans; Hydroxamic Acids; Nuclear Proteins; Receptors, Glucocorticoid; RNA-Binding Proteins; Serine-Arginine Splicing Factors

2009
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-01, Volume: 15, Issue:11

    Topics: Acetylation; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Chromatin; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-2

2009
Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells.
    Breast cancer research and treatment, 2010, Volume: 120, Issue:3

    Topics: Adenocarcinoma; Apoptosis Regulatory Proteins; Azacitidine; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytidine; Cytidine Deaminase; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Neoplasm Proteins; Receptors, Estrogen; S Phase; Tumor Stem Cell Assay; Vorinostat

2010
The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines.
    World journal of surgical oncology, 2009, May-21, Volume: 7

    Topics: Azacitidine; Breast Neoplasms; Butyrates; Cell Line, Tumor; Colorectal Neoplasms; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Humans; Radiation Dosage; Radiation-Sensitizing Agents

2009
CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.
    Breast cancer research and treatment, 2010, Volume: 120, Issue:3

    Topics: Adenocarcinoma; Azacitidine; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Hydroxamic Acids; Neoplasm Proteins; Promoter Regions, Genetic; Protein Binding; RNA, Messenger; Transcription Factors; Transcription, Genetic

2010
Effects of 5-Aza-CdR on the proliferation of human breast cancer cell line MCF-7 and on the expression of Apaf-1 gene.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2009, Volume: 29, Issue:4

    Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Female; Humans; RNA, Messenger

2009
Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter.
    Genomics, 2009, Volume: 94, Issue:6

    Topics: Azacitidine; Breast; Breast Neoplasms; Cell Line, Tumor; Cells, Cultured; Colonic Neoplasms; DNA Methylation; Female; Humans; Long Interspersed Nucleotide Elements; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic

2009
5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats.
    Toxicology letters, 2009, Dec-15, Volume: 191, Issue:2-3

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blood Urea Nitrogen; Blotting, Western; Breast Neoplasms; Cell Nucleus; Cisplatin; Colonic Neoplasms; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Synergism; Drug Therapy, Combination; Female; Histones; Kidney Diseases; Male; Mammary Neoplasms, Experimental; Metallothionein; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley

2009
Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer.
    Human pathology, 2010, Volume: 41, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Biomarkers, Tumor; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Middle Aged; Molecular Sequence Data; Neoplasm Staging; Receptor, EphA5; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger

2010
LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer.
    Oncogene, 2009, Nov-26, Volume: 28, Issue:47

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromosome Deletion; Chromosome Mapping; Chromosomes, Human, Pair 11; Colorectal Neoplasms; Decitabine; DNA Methylation; Female; Guanine Nucleotide Exchange Factors; Humans; Hydroxamic Acids; Male; Nucleic Acid Hybridization; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Rho Guanine Nucleotide Exchange Factors; Transfection; Tumor Suppressor Proteins

2009
Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Cytosine; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Sequence Analysis, DNA; Tamoxifen

2010
Effects of decitabine on the expression of selected endogenous control genes in human breast cancer cells.
    Molecular and cellular probes, 2010, Volume: 24, Issue:2

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Docetaxel; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Taxoids

2010
Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.
    Breast cancer research and treatment, 2010, Volume: 122, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Chemokines; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome, Human; Humans; Intercellular Signaling Peptides and Proteins; Nerve Growth Factors; Netrins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Ubiquitin Thiolesterase; Up-Regulation

2010
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:12

    Topics: Adenosine; Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Cluster Analysis; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunoblotting; Methylation; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Polycomb Repressive Complex 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factors

2009
[Traditional medicine CDP and promoter demethylation in breast cancer cell lines].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2009, Volume: 40, Issue:5

    Topics: Azacitidine; Breast Neoplasms; Cadherins; Cell Line, Tumor; CpG Islands; DNA Methylation; Drugs, Chinese Herbal; Genes, p16; Humans

2009
Epigenetic silencing of TNFSF7 (CD70) by DNA methylation during progression to breast cancer.
    Molecules and cells, 2010, Feb-28, Volume: 29, Issue:2

    Topics: Azacitidine; Base Sequence; Breast Neoplasms; CD27 Ligand; Cell Line, Tumor; CpG Islands; Disease Progression; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Molecular Sequence Data; Promoter Regions, Genetic; RNA, Messenger

2010
X-linked ectodermal dysplasia receptor is downregulated in breast cancer via promoter methylation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Feb-15, Volume: 16, Issue:4

    Topics: 5' Flanking Region; Azacitidine; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Down-Regulation; Ectodysplasins; Female; Humans; Promoter Regions, Genetic; Xedar Receptor

2010
Expression and regulation mechanisms of Sonic Hedgehog in breast cancer.
    Cancer science, 2010, Volume: 101, Issue:4

    Topics: Azacitidine; Breast; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Female; Hedgehog Proteins; Humans; Immunohistochemistry; Middle Aged; Neoplasms; NF-kappa B; RNA, Messenger; Transcription Factors; Up-Regulation; Zinc Finger Protein GLI1

2010
Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer.
    The Journal of biological chemistry, 2010, Apr-16, Volume: 285, Issue:16

    Topics: Animals; Azacitidine; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Primers; Enzyme Inhibitors; Epigenesis, Genetic; Female; Humans; LIM Domain Proteins; Mice; Mice, SCID; Microfilament Proteins; NF-kappa B; Promoter Regions, Genetic; Receptors, Estrogen; Tumor Stem Cell Assay

2010
BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas.
    PloS one, 2010, Mar-17, Volume: 5, Issue:3

    Topics: Alternative Splicing; Azacitidine; Breast Neoplasms; Carcinoma; CCCTC-Binding Factor; Cell Line, Tumor; Decitabine; DNA-Binding Proteins; Exons; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Polymerase Chain Reaction; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution

2010
Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells.
    International journal of oncology, 2010, Volume: 36, Issue:5

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Docetaxel; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors

2010
DNA methylation-related vitamin D receptor insensitivity in breast cancer.
    Cancer biology & therapy, 2010, Jul-01, Volume: 10, Issue:1

    Topics: Azacitidine; Blotting, Western; Bone Density Conservation Agents; Breast; Breast Neoplasms; Calcitriol; Cell Proliferation; CpG Islands; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Humans; Promoter Regions, Genetic; Receptors, Calcitriol; Regulatory Sequences, Nucleic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured

2010
Demethylating agent 5-aza-2-deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents.
    Molecular and cellular biochemistry, 2010, Volume: 342, Issue:1-2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blotting, Western; Breast Neoplasms; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; Doxorubicin; Drug Synergism; Enzyme Inhibitors; Female; Flow Cytometry; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2010
Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells.
    Anticancer research, 2010, Volume: 30, Issue:6

    Topics: Animals; Azacitidine; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; CpG Islands; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Decitabine; DNA Methylation; Extracellular Signal-Regulated MAP Kinases; Female; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Mice; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 5

2010
Epigenetic alteration of the NF-κB-inducing kinase (NIK) gene is involved in enhanced NIK expression in basal-like breast cancer.
    Cancer science, 2010, Volume: 101, Issue:11

    Topics: Acetylation; Azacitidine; Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; CpG Islands; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; NF-kappa B; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; Valproic Acid

2010
Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancer.
    The American journal of pathology, 2010, Volume: 177, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Animals; Azacitidine; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Germ-Line Mutation; Humans; Loss of Heterozygosity; Mice; Mice, SCID; Middle Aged; Polymorphism, Single Nucleotide; Receptor, Fibroblast Growth Factor, Type 4; Selection, Genetic; Xenograft Model Antitumor Assays

2010
Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells.
    Breast cancer research and treatment, 2011, Volume: 130, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; PTEN Phosphohydrolase; S-Adenosylmethionine; Tamoxifen; Tumor Burden; Xenograft Model Antitumor Assays

2011
Epigenetic up-regulation of leukemia inhibitory factor (LIF) gene during the progression to breast cancer.
    Molecules and cells, 2011, Volume: 31, Issue:2

    Topics: 5' Flanking Region; Azacitidine; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; CpG Islands; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Leukemia Inhibitory Factor; Methyl-CpG-Binding Protein 2; Molecular Sequence Data; Precancerous Conditions; Promoter Regions, Genetic; Protein Binding; RNA Interference; RNA, Messenger; Sp1 Transcription Factor; Tumor Stem Cell Assay; Up-Regulation

2011
Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel.
    BMC cancer, 2011, Jan-19, Volume: 11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Azacitidine; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Decitabine; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Humans; Hydroxamic Acids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; RNA Interference; Transplantation, Heterologous

2011
Reactivation of Syk gene by AZA suppresses metastasis but not proliferation of breast cancer cells.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mice; Mice, Nude; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Syk Kinase

2012
Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas.
    Cancer science, 2011, Volume: 102, Issue:7

    Topics: Angiopoietin-Like Protein 4; Angiopoietins; Animals; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Silencing; Hydroxamic Acids; Mammary Glands, Animal; Mammary Neoplasms, Animal; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred F344; Rats, Sprague-Dawley

2011
Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells.
    Toxicology, 2011, Jul-29, Volume: 285, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Methylation; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; TCF Transcription Factors

2011
Definition of the landscape of promoter DNA hypomethylation in liver cancer.
    Cancer research, 2011, Sep-01, Volume: 71, Issue:17

    Topics: Aged; Azacitidine; Breast Neoplasms; Carcinoma, Hepatocellular; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Ovarian Neoplasms; Promoter Regions, Genetic

2011
Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer.
    Breast cancer research and treatment, 2011, Volume: 130, Issue:1

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; HCT116 Cells; HL-60 Cells; Humans; Hydroxamic Acids; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; K562 Cells; Mutation; Neoplasm Invasiveness; Polymorphism, Genetic; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors

2011
Methylation of specific CpG sites in the P2 promoter of parathyroid hormone-related protein determines the invasive potential of breast cancer cell lines.
    Epigenetics, 2011, Volume: 6, Issue:8

    Topics: 5' Flanking Region; Azacitidine; Breast Neoplasms; Cells, Cultured; CpG Islands; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Hydroxamic Acids; Neoplasm Invasiveness; Parathyroid Hormone-Related Protein; Promoter Regions, Genetic

2011
Downregulation of ARFGEF1 and CAMK2B by promoter hypermethylation in breast cancer cells.
    BMB reports, 2011, Volume: 44, Issue:8

    Topics: Azacitidine; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Computational Biology; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; Humans; Polymerase Chain Reaction; Promoter Regions, Genetic

2011
Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS.
    Nucleic acids research, 2011, Volume: 39, Issue:22

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; DNA Helicases; DNA Methylation; DNA-Binding Proteins; Female; Gene Silencing; Histones; Humans; Polycomb-Group Proteins; Repressor Proteins; RNA Polymerase II; Transcription Initiation Site; Transcription, Genetic

2011
Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine.
    Cell biochemistry and function, 2011, Volume: 29, Issue:8

    Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Plasminogen Activator Inhibitor 1; Urokinase-Type Plasminogen Activator

2011
Epigenetic silencing of the tumor suppressor klotho in human breast cancer.
    Breast cancer research and treatment, 2012, Volume: 133, Issue:2

    Topics: Acetylation; Azacitidine; Base Sequence; Breast; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Female; Gene Silencing; Glucuronidase; Histones; Humans; Klotho Proteins; Promoter Regions, Genetic; Tumor Suppressor Proteins

2012
Twist contributes to hormone resistance in breast cancer by downregulating estrogen receptor-α.
    Oncogene, 2012, Jul-05, Volume: 31, Issue:27

    Topics: Acetylation; Animals; Antineoplastic Agents; Azacitidine; Breast Neoplasms; Capillary Permeability; Cell Line, Tumor; Chromatin; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Down-Regulation; Drug Resistance, Neoplasm; E-Box Elements; Estrogen Receptor alpha; Estrogens; Female; Histone Deacetylase 1; Histones; Humans; Mice; Nuclear Proteins; Promoter Regions, Genetic; Protein Transport; RNA, Small Interfering; Tamoxifen; Twist-Related Protein 1; Valproic Acid

2012
Integrated epigenetics of human breast cancer: synoptic investigation of targeted genes, microRNAs and proteins upon demethylation treatment.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Electrophoresis, Gel, Two-Dimensional; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; MicroRNAs; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2011
DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells.
    Cancer letters, 2012, Volume: 316, Issue:1

    Topics: Apoptosis; Azacitidine; Breast Neoplasms; Cell Cycle; Cell Growth Processes; Decitabine; DNA Methylation; DNA Mismatch Repair; DNA Repair; Drug Interactions; Epigenesis, Genetic; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic

2012
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines.
    Epigenetics, 2011, Volume: 6, Issue:12

    Topics: Acetylation; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromosomes, Human, Pair 3; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Lysine; Multigene Family; Promoter Regions, Genetic; Tumor Suppressor Proteins

2011
Increased proliferation and chemosensitivity of human mesenchymal stromal cells expressing fusion yeast cytosine deaminase.
    Stem cell research, 2012, Volume: 8, Issue:2

    Topics: Adipose Tissue; Apoptosis; Azacitidine; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cytarabine; Cytosine Deaminase; Drug Screening Assays, Antitumor; Female; Fluorouracil; Genetic Engineering; Green Fluorescent Proteins; Humans; Mesenchymal Stem Cells; Recombinant Fusion Proteins; Retroviridae; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transduction, Genetic; Transgenes

2012
Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.
    Cancer cell, 2012, Mar-20, Volume: 21, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Bone Marrow Cells; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Transformation, Neoplastic; Decitabine; DNA Damage; DNA Methylation; DNA Modification Methylases; Gene Silencing; Humans; Leukemia; Mice; Molecular Sequence Data; Neoplastic Stem Cells; Promoter Regions, Genetic; Signal Transduction; Tumor Cells, Cultured

2012
MTA1 expression correlates significantly with ER-alpha methylation in breast cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2012, Volume: 33, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Mammary Glands, Human; Methylation; Middle Aged; Neoplasm Staging; Repressor Proteins; Trans-Activators

2012
The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer.
    Epigenetics, 2012, Volume: 7, Issue:8

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Breast Neoplasms; Carbohydrate Epimerases; Chromatin; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; MCF-7 Cells; Promoter Regions, Genetic; Protein Processing, Post-Translational; Transcription Factor 4; Transcription Factors; Transcription, Genetic; Wnt Signaling Pathway

2012
Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Apoptosis; Azacitidine; Breast Neoplasms; Cell Proliferation; DNA Methylation; Drug Resistance, Neoplasm; ErbB Receptors; Estrogens; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Neoplasm; Growth Differentiation Factor 15; Humans; MCF-7 Cells; Quinazolines; Receptors, Estrogen; Receptors, Progesterone; Recombinant Proteins; Tamoxifen; Trefoil Factor-1; Tumor Suppressor Proteins

2012
Epigenetic modulation of the biophysical properties of drug-resistant cell lipids to restore drug transport and endocytic functions.
    Molecular pharmaceutics, 2012, Sep-04, Volume: 9, Issue:9

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Biological Transport; Breast Neoplasms; Cell Membrane; Decitabine; DNA Methylation; Doxorubicin; Drug Delivery Systems; Drug Resistance, Neoplasm; Endocytosis; Epigenesis, Genetic; Epigenomics; Female; Humans; Lipid Metabolism; MCF-7 Cells

2012
Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Breast Neoplasms; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Decitabine; Depsipeptides; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Histone Deacetylase Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Kidney Neoplasms; Methyltransferases; Recombinant Proteins; Tumor Suppressor Proteins

2012
Global identification of genes regulated by estrogen signaling and demethylation in MCF-7 breast cancer cells.
    Biochemical and biophysical research communications, 2012, Sep-14, Volume: 426, Issue:1

    Topics: Azacitidine; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Estradiol; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Promoter Regions, Genetic; Proteins; Signal Transduction; Transcriptome

2012
ING1 and 5-azacytidine act synergistically to block breast cancer cell growth.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Hydroxamic Acids; Indoles; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Mice; Mice, SCID; Nuclear Proteins; Panobinostat; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2012
5-aza-2'-Deoxycytidine enhances the radiosensitivity of breast cancer cells.
    Cancer biotherapy & radiopharmaceuticals, 2013, Volume: 28, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Breast Neoplasms; Cell Cycle; Cell Proliferation; Colony-Forming Units Assay; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2013
Epigenetic mechanisms regulate the prostaglandin E receptor 2 in breast cancer.
    The Journal of steroid biochemistry and molecular biology, 2012, Volume: 132, Issue:3-5

    Topics: Adipose Tissue; Azacitidine; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Receptors, Prostaglandin E, EP2 Subtype; Reference Values; Stromal Cells

2012
Transcriptional regulation of hTREX84 in human cancer cells.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Azacitidine; Base Sequence; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; Decitabine; DNA-Binding Proteins; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Nuclear Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; RNA-Binding Proteins; Sequence Analysis, DNA; Sulfites; Transcription Factor RelA; Transcription, Genetic

2012
Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer.
    Oncogene, 2013, Aug-22, Volume: 32, Issue:34

    Topics: Azacitidine; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; MCF-7 Cells; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sequence Analysis, DNA; tert-Butylhydroperoxide; Transcription Factor AP-2; Transcription, Genetic

2013
CpG island shore methylation regulates caveolin-1 expression in breast cancer.
    Oncogene, 2013, Sep-19, Volume: 32, Issue:38

    Topics: Azacitidine; Breast Neoplasms; Caveolin 1; Cell Line, Tumor; CpG Islands; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Oncogene Proteins; Promoter Regions, Genetic

2013
Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells.
    Journal of cellular physiology, 2013, Volume: 228, Issue:6

    Topics: Azacitidine; Binding Sites; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Embryonal; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Embryonal Carcinoma Stem Cells; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Genes, Reporter; GPI-Linked Proteins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Luciferases; MCF-7 Cells; Neoplasm Invasiveness; Neoplasm Proteins; Nuclear Receptor Subfamily 6, Group A, Member 1; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA Interference; RNA, Messenger; Time Factors; Tissue Array Analysis; Transcription, Genetic; Transfection; Tretinoin; Valproic Acid

2013
Highly synergistic effect of sequential treatment with epigenetic and anticancer drugs to overcome drug resistance in breast cancer cells is mediated via activation of p21 gene expression leading to G2/M cycle arrest.
    Molecular pharmaceutics, 2013, Jan-07, Volume: 10, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Carcinogens; Cell Cycle Checkpoints; Cell Division; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Epigenesis, Genetic; Epigenomics; Female; G2 Phase; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Internationality; MCF-7 Cells; Vorinostat

2013
Identification of novel breast cancer-associated transcripts by UniGene database mining and gene expression analysis in normal and malignant cells.
    Genes, chromosomes & cancer, 2013, Volume: 52, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alternative Splicing; Azacitidine; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Line, Tumor; Computational Biology; Data Mining; Databases, Nucleic Acid; Expressed Sequence Tags; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Neoplasm Grading; Neoplasm Staging; Transcription, Genetic; Transcriptome

2013
Efficacy of decitabine-loaded nanogels in overcoming cancer drug resistance is mediated via sustained DNA methyltransferase 1 (DNMT1) depletion.
    Cancer letters, 2013, Apr-30, Volume: 331, Issue:1

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Delivery Systems; Drug Resistance, Neoplasm; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Humans; Nanogels; Polyethylene Glycols; Polyethyleneimine; Tumor Cells, Cultured

2013
Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer.
    Molecular cancer, 2013, Feb-04, Volume: 12

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance, Neoplasm; Drug Synergism; Epigenesis, Genetic; Estradiol; Estrogen Receptor alpha; Female; Gene Expression; Genistein; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Mice; Mice, Nude; Mice, Transgenic; Proliferating Cell Nuclear Antigen; Promoter Regions, Genetic; Tamoxifen; Tumor Burden; Xenograft Model Antitumor Assays

2013
Synergistic antineoplastic action of DNA methylation inhibitor 5-AZA-2'-deoxycytidine and histone deacetylase inhibitor depsipeptide on human breast carcinoma cells.
    International journal of cancer, 2003, Jan-10, Volume: 103, Issue:2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Decitabine; DNA Methylation; DNA Primers; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Female; Gelsolin; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; In Vitro Techniques; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serpins; Tumor Cells, Cultured

2003
Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma.
    Cancer research, 2003, Feb-01, Volume: 63, Issue:3

    Topics: Azacitidine; Breast Neoplasms; CpG Islands; Decitabine; DNA Methylation; Epithelial Cells; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Nerve Tissue Proteins; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synucleins; Tumor Cells, Cultured

2003
Interaction of 5-aza-2'-deoxycytidine and depsipeptide on antineoplastic activity and activation of 14-3-3sigma, E-cadherin and tissue inhibitor of metalloproteinase 3 expression in human breast carcinoma cells.
    Anti-cancer drugs, 2003, Volume: 14, Issue:3

    Topics: 14-3-3 Proteins; Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Breast Neoplasms; Cadherins; Cell Line, Tumor; Decitabine; Depsipeptides; DNA; DNA Modification Methylases; Dose-Response Relationship, Drug; Drug Synergism; Exonucleases; Exoribonucleases; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Inhibitory Concentration 50; Neoplasm Proteins; Peptides, Cyclic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-3; Tumor Stem Cell Assay

2003
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers.
    Cancer genetics and cytogenetics, 2003, Jan-15, Volume: 140, Issue:2

    Topics: Adenocarcinoma; Azacitidine; Base Sequence; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; GTPase-Activating Proteins; Humans; Liver Neoplasms; Male; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Promoter Regions, Genetic; Prostatic Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins

2003
Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Head and Neck Neoplasms; Humans; Hydralazine; Mice; Mice, Nude; Procainamide; Receptors, Estrogen; Receptors, Retinoic Acid; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2003
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression.
    Oncogene, 2003, Jun-05, Volume: 22, Issue:23

    Topics: Azacitidine; Breast Neoplasms; Chromatin; Cytosine; Desmocollins; DNA Methylation; DNA-Cytosine Methylases; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Membrane Glycoproteins; Mutation; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Proteins; Serpins; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2003
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.
    Nature genetics, 2003, Volume: 34, Issue:3

    Topics: Animals; Azacitidine; Breast Neoplasms; Carrier Proteins; Case-Control Studies; Cell Adhesion Molecules; Chromosomes, Human, Pair 11; CpG Islands; DNA; DNA Methylation; Enzyme Inhibitors; Female; Genes, Tumor Suppressor; GPI-Linked Proteins; Humans; Loss of Heterozygosity; Mice; Mice, Nude; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Neoplasms, Glandular and Epithelial; Nerve Tissue Proteins; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tumor Cells, Cultured

2003
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
    Cancer research, 2003, Jul-15, Volume: 63, Issue:14

    Topics: Alleles; Animals; Azacitidine; Breast Neoplasms; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Mice; Promoter Regions, Genetic; rho GTP-Binding Proteins; Tumor Cells, Cultured

2003
UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.
    Oncogene, 2003, Jul-17, Volume: 22, Issue:29

    Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 22; CpG Islands; DNA Methylation; DNA-Binding Proteins; Electron Transport Complex III; Exons; Extrachromosomal Inheritance; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Kruppel-Like Transcription Factors; Molecular Sequence Data; Neoplasm Proteins; Ovarian Neoplasms; Promoter Regions, Genetic; Proteins; Repressor Proteins; RNA-Binding Protein EWS; Sarcoma; Soft Tissue Neoplasms; Translocation, Genetic; Tumor Cells, Cultured

2003
Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.
    Cancer research, 2003, Aug-01, Volume: 63, Issue:15

    Topics: Azacitidine; Breast Neoplasms; Carcinoma, Squamous Cell; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Gene Expression; Humans; Lung Neoplasms; Microsatellite Repeats; PAX5 Transcription Factor; Promoter Regions, Genetic; Transcription Factors; Tumor Cells, Cultured

2003
Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers.
    International journal of cancer, 2003, Nov-10, Volume: 107, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cyclin D2; Cyclins; DNA Methylation; Female; Humans; Lung Neoplasms; Middle Aged; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured

2003
Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model.
    The Journal of pathology, 2003, Volume: 201, Issue:2

    Topics: Age Factors; Azacitidine; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chi-Square Distribution; Decitabine; DNA Methylation; DNA Modification Methylases; Estrogen Receptor beta; Female; Gene Silencing; Humans; Immunohistochemistry; Lymphatic Metastasis; Neoplasm Recurrence, Local; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Uterine Cervical Dysplasia

2003
A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.
    Breast cancer research and treatment, 2003, Volume: 81, Issue:3

    Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Division; Decitabine; DNA Modification Methylases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrogen Receptor alpha; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxylamines; Inhibitory Concentration 50; Quinolines; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tumor Cells, Cultured

2003
CHFR-associated early G2/M checkpoint defects in breast cancer cells.
    Molecular carcinogenesis, 2004, Volume: 39, Issue:1

    Topics: Azacitidine; Blotting, Western; Breast Neoplasms; Cell Cycle Proteins; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Flow Cytometry; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Mitosis; Mitotic Index; Neoplasm Proteins; Poly-ADP-Ribose Binding Proteins; Tumor Cells, Cultured; Ubiquitin-Protein Ligases

2004
MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine.
    Cancer biology & therapy, 2004, Volume: 3, Issue:6

    Topics: Acetylation; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Breast Neoplasms; Chromatin; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Modification Methylases; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Promoter Regions, Genetic; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured

2004
Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines.
    Anti-cancer drugs, 2004, Volume: 15, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cadherins; Cell Line, Tumor; Decitabine; DNA; Docetaxel; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Male; Prostatic Neoplasms; Proteins; Serpins; Taxoids; Time Factors

2004
Less frequent promoter hypermethylation of DLC-1 gene in primary breast cancers.
    Oncology reports, 2004, Volume: 12, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Female; Gene Frequency; Gene Silencing; GTPase-Activating Proteins; Humans; Neoplasm Invasiveness; Polymerase Chain Reaction; Promoter Regions, Genetic; Tumor Suppressor Proteins

2004
Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites.
    Breast cancer research : BCR, 2004, Volume: 6, Issue:4

    Topics: Azacitidine; Breast Neoplasms; Carcinoma; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Humans; Nucleic Acid Amplification Techniques; Promoter Regions, Genetic

2004
Epigenetic regulation of MDR1 gene in breast cancer: CpG methylation status dominates the stable maintenance of a silent gene.
    Cancer biology & therapy, 2004, Volume: 3, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Breast Neoplasms; Chromatin; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Promoter Regions, Genetic

2004
Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness.
    International journal of cancer, 2005, Feb-10, Volume: 113, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast; Breast Neoplasms; Carcinoma, Ductal; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Precursors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intracellular Signaling Peptides and Proteins; Neoplasm Invasiveness; Phenotype; Protein-Tyrosine Kinases; Stilbenes; Syk Kinase

2005
Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines.
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:11

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Female; Humans; Male; Nerve Tissue Proteins; Prostatic Neoplasms; RNA, Messenger; Stomach Neoplasms

2004
Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells.
    Cancer biology & therapy, 2004, Volume: 3, Issue:12

    Topics: Acetylation; Azacitidine; Breast Neoplasms; Chemokines, C; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lymphokines; Oligonucleotide Array Sequence Analysis; Phosphoprotein Phosphatases; Protein Phosphatase 2; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Tumor Cells, Cultured

2004
Characterization of {gamma}-aminobutyric acid type A receptor-associated protein, a novel tumor suppressor, showing reduced expression in breast cancer.
    Cancer research, 2005, Jan-15, Volume: 65, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Azacitidine; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Mutational Analysis; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Microtubule-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subcellular Fractions; Transfection; Up-Regulation

2005
Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer.
    Oncogene, 2005, Apr-14, Volume: 24, Issue:16

    Topics: Azacitidine; Base Sequence; Breast Neoplasms; Cell Cycle Proteins; Chromosome Mapping; DNA Methylation; Epithelial Cells; Female; Gene Expression Profiling; Humans; Molecular Sequence Data; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Tumor Cells, Cultured

2005
Release of methyl CpG binding proteins and histone deacetylase 1 from the Estrogen receptor alpha (ER) promoter upon reactivation in ER-negative human breast cancer cells.
    Molecular endocrinology (Baltimore, Md.), 2005, Volume: 19, Issue:7

    Topics: Acetylation; Azacitidine; Breast Neoplasms; Chromatin; Chromatin Immunoprecipitation; Chromosomal Proteins, Non-Histone; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Methyl-CpG-Binding Protein 2; Promoter Regions, Genetic; Repressor Proteins; Transcription Factors; Tumor Cells, Cultured

2005
Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Decitabine; DNA Primers; Enzyme Inhibitors; Histone Deacetylases; Histones; Humans; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Time Factors; Tretinoin; Valproic Acid

2005
CRD-BP/IMP1 expression characterizes cord blood CD34+ stem cells and affects c-myc and IGF-II expression in MCF-7 cancer cells.
    The Journal of biological chemistry, 2005, May-20, Volume: 280, Issue:20

    Topics: Adult; Antigens, CD34; Azacitidine; Base Sequence; Bone Marrow Cells; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA, Neoplasm; Female; Fetal Blood; Gene Expression; Genes, myc; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Insulin-Like Growth Factor II; Pluripotent Stem Cells; RNA Interference; RNA-Binding Proteins; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Transfection

2005
Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta.
    Oncogene, 2005, Jul-28, Volume: 24, Issue:32

    Topics: Azacitidine; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Introns; Molecular Sequence Data; Neoplasm Metastasis; Promoter Regions, Genetic; RNA, Messenger; Transforming Growth Factor beta; Tropomyosin

2005
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-15, Volume: 11, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Azacitidine; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Cadherins; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Ki-67 Antigen; Middle Aged; Neoplasm Invasiveness; Predictive Value of Tests; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Analysis; Tumor Suppressor Protein p53

2005
Activator protein 2alpha status determines the chemosensitivity of cancer cells: implications in cancer chemotherapy.
    Cancer research, 2005, Oct-01, Volume: 65, Issue:19

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Silencing; Humans; Mice; Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transcription Factor AP-2

2005
The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer.
    Cancer research, 2005, Oct-01, Volume: 65, Issue:19

    Topics: Azacitidine; Base Sequence; Breast Neoplasms; Breast Neoplasms, Male; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; Chromosomes, Human, Pair 11; Cyclin D1; Decitabine; DNA Methylation; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Introns; Male; Middle Aged; Molecular Sequence Data; RNA, Messenger

2005
BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy.
    Cancer research, 2005, Dec-01, Volume: 65, Issue:23

    Topics: Aneuploidy; Antimetabolites, Antineoplastic; Azacitidine; BRCA1 Protein; Breast; Breast Neoplasms; Cell Line, Tumor; Chromosomes, Human, Pair 17; Decitabine; DNA Methylation; Female; Gene Dosage; Gene Expression; Genes, BRCA1; Humans; Hydroxamic Acids; Lymphocytes; Middle Aged; Promoter Regions, Genetic; RNA, Messenger

2005
Promoter methylation reduces C/EBPdelta (CEBPD) gene expression in the SUM-52PE human breast cancer cell line and in primary breast tumors.
    Breast cancer research and treatment, 2006, Volume: 95, Issue:2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Breast Neoplasms; CCAAT-Enhancer-Binding Protein-delta; Chromatin Immunoprecipitation; DNA Methylation; Down-Regulation; Electrophoretic Mobility Shift Assay; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Resting Phase, Cell Cycle; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured

2006
Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer.
    Cancer biology & therapy, 2006, Volume: 5, Issue:3

    Topics: Acetylation; Azacitidine; Breast; Breast Neoplasms; Cell Line; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA

2006
[The synergistic inhibitory effect of 5-aza-2-deoxycytidine and Tamoxifen on estrogen receptor alpha negative breast cancer cell lines in vitro].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2005, Dec-01, Volume: 43, Issue:23

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; Drug Synergism; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen

2005
Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Apr-01, Volume: 12, Issue:7 Pt 1

    Topics: Azacitidine; Breast Neoplasms; Calcitriol; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Decitabine; Female; Humans; Hydroxamic Acids; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Receptors, Calcitriol; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Time Factors; Tumor Cells, Cultured

2006
Methylation status of the Ep-CAM promoter region in human breast cancer cell lines and breast cancer tissue.
    Cancer letters, 2007, Feb-08, Volume: 246, Issue:1-2

    Topics: Antigens, Neoplasm; Azacitidine; Breast; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Colon; CpG Islands; Decitabine; DNA Methylation; Epithelial Cell Adhesion Molecule; Female; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Promoter Regions, Genetic; RNA, Messenger

2007
Epigenetic inactivation of Betaig-h3 gene in human cancer cells.
    Cancer research, 2006, May-01, Volume: 66, Issue:9

    Topics: Azacitidine; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Luciferases; Lung Neoplasms; Male; Neoplasms; Promoter Regions, Genetic; Prostatic Neoplasms; Transforming Growth Factor beta

2006
Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes.
    Cancer research, 2006, Jun-15, Volume: 66, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Drug Synergism; Estrogen Antagonists; Estrogen Receptor alpha; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Promoter Regions, Genetic; Repressor Proteins; RNA, Messenger; Sin3 Histone Deacetylase and Corepressor Complex; Tamoxifen

2006
Effect of histone deacetylase inhibitor LAQ824 on antineoplastic action of 5-Aza-2'-deoxycytidine (decitabine) on human breast carcinoma cells.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:5

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Decitabine; DNA; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Flow Cytometry; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Neoplastic Stem Cells; S Phase; Time Factors

2006
Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer.
    Biological chemistry, 2006, Volume: 387, Issue:6

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Calcitriol; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Kallikreins; Promoter Regions, Genetic; Transcription, Genetic

2006
The epigenetic basis for the aberrant expression of kallikreins in human cancers.
    Biological chemistry, 2006, Volume: 387, Issue:6

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Male; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms

2006
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer.
    Cancer research, 2006, Jul-01, Volume: 66, Issue:13

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Targeting; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Promoter Regions, Genetic

2006
Clinical evaluation of E-cadherin expression and its regulation mechanism in epithelial ovarian cancer.
    Clinical & experimental metastasis, 2006, Volume: 23, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cadherins; Cell Line, Tumor; DNA Primers; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction

2006
DNA methylation-dependent silencing of CST6 in human breast cancer cell lines.
    Laboratory investigation; a journal of technical methods and pathology, 2006, Volume: 86, Issue:12

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; CpG Islands; Cystatin M; Cystatins; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Promoter Regions, Genetic

2006
Alteration of DNA methylation status in K562 and MCF-7 cancer cell lines by nucleoside analogues.
    Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:9-11

    Topics: Azacitidine; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cladribine; Decitabine; DNA Methylation; Estrogen Receptor alpha; Genes, APC; Genes, BRCA1; Humans; K562 Cells; Nucleosides; Promoter Regions, Genetic; PTEN Phosphohydrolase; Vidarabine

2006
Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.
    Cancer research, 2006, Nov-01, Volume: 66, Issue:21

    Topics: ADP-Ribosylation Factors; Apoptosis; Azacitidine; Breast Neoplasms; Cell Proliferation; Decitabine; Down-Regulation; Female; Genes, Tumor Suppressor; Humans; Ovarian Neoplasms

2006
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.
    PLoS medicine, 2006, Volume: 3, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Cathepsin K; Cathepsins; Colonic Neoplasms; CpG Islands; Cyclin A; Cyclin A1; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Profiling; Humans; Lung Neoplasms; Male; Middle Aged; MSX1 Transcription Factor; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Transcription Factors; Tumor Cells, Cultured

2006
Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers.
    Annals of surgical oncology, 2007, Volume: 14, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; CpG Islands; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Male; Middle Aged; Promoter Regions, Genetic; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

2007
Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Jan-01, Volume: 13, Issue:1

    Topics: Adenoviridae; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; Disease Progression; DNA Methylation; DNA, Complementary; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Neoplasm Proteins; Oxidoreductases; RNA Interference; Time Factors; Tumor Suppressor Proteins; WW Domain-Containing Oxidoreductase

2007
Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.
    Breast cancer research and treatment, 2007, Volume: 103, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Carcinoma; Cell Adhesion; Cell Adhesion Molecule-1; Cell Adhesion Molecules; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulins; Membrane Proteins; Microfilament Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sulfites; Tumor Suppressor Proteins

2007
Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin.
    Cancer research, 2007, Feb-01, Volume: 67, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Decitabine; Down-Regulation; Doxorubicin; Drug Synergism; Enzyme Activation; Histone Deacetylase 1; Histone Deacetylases; Humans; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Transfection

2007
Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer.
    Cancer biology & therapy, 2006, Volume: 5, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Decitabine; Dinucleoside Phosphates; DNA Methylation; DNA Primers; Epigenesis, Genetic; ErbB Receptors; Female; Gefitinib; Genetic Therapy; Humans; Organ Specificity; Quinazolines; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction

2006
Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer.
    International journal of cancer, 2007, Aug-01, Volume: 121, Issue:3

    Topics: Adult; Aged; Azacitidine; Brain Neoplasms; Breast Neoplasms; CpG Islands; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Homeodomain Proteins; Humans; Middle Aged; Oligonucleotide Array Sequence Analysis; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins

2007
[Expression of ER alpha in chemically induced MDA-MB-435 cells and its responsiveness to endocrine].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:12

    Topics: Animals; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Modification Methylases; Enzyme Inhibitors; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Ovariectomy; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trefoil Factor-1; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2006
[Demethylation of estrogen receptor gene and its re-expression in estrogen receptor-negative breast].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:12

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azacitidine; Base Sequence; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Estrogen Receptor Modulators; Tamoxifen

2006
Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer.
    Cancer research, 2007, Aug-15, Volume: 67, Issue:16

    Topics: Azacitidine; Breast Neoplasms; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; E1A-Associated p300 Protein; Estrogen Receptor alpha; Humans; Promoter Regions, Genetic; Retinoblastoma Protein; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130; Ubiquitin-Protein Ligases

2007
Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR.
    Breast cancer research and treatment, 2008, Volume: 111, Issue:1

    Topics: 3' Untranslated Regions; Antigens, Surface; Azacitidine; Base Sequence; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Decitabine; ELAV Proteins; ELAV-Like Protein 1; Enzyme Inhibitors; Epigenesis, Genetic; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Humans; Hydroxamic Acids; Immunoprecipitation; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA-Binding Proteins; RNA, Messenger; Transfection

2008
Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer.
    The Journal of pathology, 2008, Volume: 214, Issue:1

    Topics: Azacitidine; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; MicroRNAs; RNA, Neoplasm; Tumor Cells, Cultured

2008
The effects of nucleoside analogues on promoter methylation of selected tumor suppressor genes in MCF-7 and MDA-MB-231 breast cancer cell lines.
    Nucleosides, nucleotides & nucleic acids, 2007, Volume: 26, Issue:8-9

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cladribine; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Genes, APC; Genes, BRCA1; Genes, Tumor Suppressor; Humans; Nucleosides; Promoter Regions, Genetic; PTEN Phosphohydrolase; Receptors, Retinoic Acid; Vidarabine

2007
Effects of 5-Aza-CdR on cell proliferation of breast cancer cell line MDA-MB-435S and expression of maspin gene.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2007, Volume: 27, Issue:5

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; Female; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serpins

2007
DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines.
    Molecular cancer, 2008, Jan-25, Volume: 7

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast; Breast Neoplasms; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Phenotype; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2008
ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:8

    Topics: Animals; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Female; Flow Cytometry; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen; Trefoil Factor-1; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2008
Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.
    Breast cancer research and treatment, 2009, Volume: 113, Issue:2

    Topics: Azacitidine; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Checkpoint Kinase 2; Codon, Nonsense; Colorectal Neoplasms; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, cdc; Genes, p53; Humans; Male; Neoplasm Proteins; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Tumor Suppressor Protein p53

2009
Phenotypic variability in anchorage-independent growth by a human breast tumor cell line.
    Journal of the National Cancer Institute, 1984, Volume: 72, Issue:4

    Topics: Azacitidine; Breast Neoplasms; Carcinosarcoma; Cell Adhesion; Cell Division; Cell Line; Culture Media; Female; Gene Expression Regulation; Hot Temperature; Humans; Isomerism; Methylcellulose; Phenotype

1984
Induction of estrogen independence of ZR-75-1 human breast cancer cells by epigenetic alterations.
    Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:11

    Topics: Azacitidine; Breast Neoplasms; Down-Regulation; ErbB Receptors; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Keratins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Polyunsaturated Alkamides; Proteins; Receptor, ErbB-2; Receptors, Estradiol; Receptors, Progesterone; Tamoxifen; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

1994
Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.
    Cancer research, 1995, Jun-01, Volume: 55, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Guanine; Humans; Methylation; Molecular Sequence Data; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured

1995
Regulation of gene expression involved in the progression of human breast cancer to hormone independence.
    Annals of the New York Academy of Sciences, 1993, Jun-11, Volume: 684

    Topics: Azacitidine; Binding Sites; Breast Neoplasms; Cell Division; DNA; Epidermal Growth Factor; ErbB Receptors; Estrogens; Gene Expression Regulation, Neoplastic; Humans; Methylation; Receptors, Estrogen; Tumor Cells, Cultured

1993
Silencing of the mammary-derived growth inhibitor (MDGI) gene in breast neoplasms is associated with epigenetic changes.
    Cancer research, 1996, Nov-01, Volume: 56, Issue:21

    Topics: Azacitidine; Breast Neoplasms; Carrier Proteins; DNA Methylation; Fatty Acid Binding Protein 3; Fatty Acid-Binding Proteins; Female; Growth Inhibitors; Humans; Polymerase Chain Reaction; Tumor Cells, Cultured

1996
Expression of MAGE and BAGE genes in Japanese breast cancers.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:4

    Topics: Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Decitabine; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Humans; Japan; Melanoma-Specific Antigens; Neoplasm Proteins; Tumor Cells, Cultured

1997
Transcriptional defects underlie loss of E-cadherin expression in breast cancer.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1997, Volume: 8, Issue:7

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cadherins; Cloning, Molecular; Decitabine; DNA Methylation; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Trans-Activators; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured

1997
Role of estrogen receptor gene demethylation and DNA methyltransferase.DNA adduct formation in 5-aza-2'deoxycytidine-induced cytotoxicity in human breast cancer cells.
    The Journal of biological chemistry, 1997, Dec-19, Volume: 272, Issue:51

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Decitabine; DNA Adducts; DNA Methylation; DNA Modification Methylases; Humans; Receptors, Estrogen; Tumor Cells, Cultured

1997
Methylation-mediated regulation of the glutathione S-transferase P1 gene in human breast cancer cells.
    Gene, 1998, Mar-27, Volume: 210, Issue:1

    Topics: Azacitidine; Blotting, Southern; Breast Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Neoplasm Proteins; Promoter Regions, Genetic; Receptors, Estrogen; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1998
Induction of transforming growth factor-beta receptor type II expression in estrogen receptor-positive breast cancer cells through SP1 activation by 5-aza-2'-deoxycytidine.
    The Journal of biological chemistry, 1998, Jun-26, Volume: 273, Issue:26

    Topics: Activin Receptors, Type I; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Breast Neoplasms; Decitabine; Female; Humans; Insulin-Like Growth Factor II; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Estrogen; Receptors, Transforming Growth Factor beta; Repressor Proteins; Sp1 Transcription Factor; Transforming Growth Factor beta; Tumor Cells, Cultured

1998
Transcriptional regulation of urokinase (uPA) gene expression in breast cancer cells: role of DNA methylation.
    International journal of cancer, 1999, May-05, Volume: 81, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Cell Line; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Transcription, Genetic; Urokinase-Type Plasminogen Activator

1999
DNA methylation of retinoic acid receptor beta in breast cancer and possible therapeutic role of 5-aza-2'-deoxycytidine.
    Anti-cancer drugs, 1999, Volume: 10, Issue:5

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Cell Division; Decitabine; DNA Methylation; Female; Humans; Receptors, Retinoic Acid; Tumor Cells, Cultured

1999
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells.
    Oncogene, 2000, Mar-16, Volume: 19, Issue:12

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast; Breast Neoplasms; Cell Line; Chromatin; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Female; Gene Expression Regulation; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Retinoic Acid; Tretinoin; Tumor Cells, Cultured

2000
High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, May-23, Volume: 97, Issue:11

    Topics: 14-3-3 Proteins; Azacitidine; Breast; Breast Neoplasms; Cell Cycle Proteins; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; CpG Islands; Decitabine; DNA Methylation; DNA Repair; Epithelial Cells; Female; G2 Phase; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Neoplasm Proteins; Protein Biosynthesis; Proteins; Radiation Tolerance; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

2000
Regional methylation of the 5' end CpG island of BRCA1 is associated with reduced gene expression in human somatic cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:11

    Topics: Azacitidine; Breast Neoplasms; Cell Line; Cervix Uteri; Chromosomal Proteins, Non-Histone; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation; Gene Silencing; Genes, BRCA1; Germ Cells; Humans; Kidney; Male; Methyl-CpG-Binding Protein 2; Promoter Regions, Genetic; Repressor Proteins; Transcriptional Activation; Transfection

2000
Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells.
    Oncogene, 2000, Aug-17, Volume: 19, Issue:35

    Topics: Adenocarcinoma; Azacitidine; Base Sequence; Breast Neoplasms; Clone Cells; CpG Islands; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Molecular Sequence Data; Neoplasm Proteins; Promoter Regions, Genetic; Receptors, Retinoic Acid; Sequence Analysis, DNA; Transcriptional Activation; Transfection; Tretinoin; Tumor Cells, Cultured

2000
Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency.
    Oncogene, 2000, Sep-21, Volume: 19, Issue:40

    Topics: Activin Receptors, Type I; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Colonic Neoplasms; Cyclin A; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Sp1 Transcription Factor; Transcriptional Activation; Transfection; Tumor Cells, Cultured

2000
Biallelic inactivation of retinoic acid receptor beta2 gene by epigenetic change in breast cancer.
    The American journal of pathology, 2001, Volume: 158, Issue:1

    Topics: Alleles; Azacitidine; Breast Neoplasms; Chromosomes, Human, Pair 3; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Loss of Heterozygosity; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tumor Cells, Cultured; Up-Regulation

2001
Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition.
    Cancer research, 2001, Mar-01, Volume: 61, Issue:5

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Movement; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Monomeric GTP-Binding Proteins; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Promoter Regions, Genetic; Transcription Factors; Transfection; Tumor Cells, Cultured

2001
5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.
    Cancer research, 2001, May-01, Volume: 61, Issue:9

    Topics: Acid Anhydride Hydrolases; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Blotting, Northern; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Loss of Heterozygosity; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Protein Biosynthesis; Proteins; RNA, Messenger

2001
5-azaC treatment enhances expression of transforming growth factor-beta receptors through down-regulation of Sp3.
    The Journal of biological chemistry, 2001, Aug-31, Volume: 276, Issue:35

    Topics: Activin Receptors, Type I; Azacitidine; Breast Neoplasms; Cell Nucleus; Colonic Neoplasms; DNA-Binding Proteins; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sp3 Transcription Factor; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2001
Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells.
    Cancer chemotherapy and pharmacology, 2001, Volume: 48, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Decitabine; Enzyme Inhibitors; Estrogen Receptor alpha; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Receptors, Estrogen; Receptors, Retinoic Acid; Tumor Cells, Cultured

2001
Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.
    The Journal of biological chemistry, 2001, Oct-26, Volume: 276, Issue:43

    Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Biological Transport; Breast Neoplasms; Carrier Proteins; CpG Islands; Decitabine; Dipyridamole; DNA Methylation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Female; Folic Acid Antagonists; Gene Silencing; Histone Deacetylases; Histones; Humans; Ion Pumps; Membrane Transport Proteins; Methotrexate; Promoter Regions, Genetic; Reduced Folate Carrier Protein

2001
Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences.
    Oncogene, 2001, Aug-23, Volume: 20, Issue:37

    Topics: Amino Acid Motifs; Azacitidine; Base Sequence; Binding Sites; Breast Neoplasms; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Exons; gamma-Synuclein; Humans; Introns; Models, Genetic; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Nerve Tissue Proteins; Promoter Regions, Genetic; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured

2001
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.
    Cancer research, 2001, Oct-01, Volume: 61, Issue:19

    Topics: Acetylation; Azacitidine; Breast Neoplasms; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Fulvestrant; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured

2001
CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression.
    Cancer research, 2001, Nov-01, Volume: 61, Issue:21

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Breast Neoplasms; CpG Islands; Decitabine; DNA Methylation; Exons; Gene Expression Regulation, Neoplastic; Humans; Introns; Kallikreins; Luciferases; Promoter Regions, Genetic; RNA, Messenger

2001
Glypican-3 expression is silenced in human breast cancer.
    Oncogene, 2001, Nov-01, Volume: 20, Issue:50

    Topics: Azacitidine; Breast; Breast Neoplasms; Carcinoma, Hepatocellular; Decitabine; DNA Methylation; DNA, Neoplasm; Dosage Compensation, Genetic; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Glypicans; Heparan Sulfate Proteoglycans; Humans; Liver Neoplasms; Loss of Heterozygosity; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Tumor Stem Cell Assay; X Chromosome

2001
Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer.
    British journal of cancer, 2001, Dec-14, Volume: 85, Issue:12

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Carcinoma; Chromosome Deletion; Chromosomes, Human, Pair 17; Cohort Studies; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Follow-Up Studies; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, p53; Humans; Kruppel-Like Transcription Factors; Loss of Heterozygosity; Neoplasm Proteins; Prognosis; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Transcription Factors; Tumor Cells, Cultured

2001
Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer.
    Carcinogenesis, 2002, Volume: 23, Issue:2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Connexin 26; Connexins; CpG Islands; Decitabine; DNA Methylation; Female; Humans; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Sulfites; Transcription, Genetic; Tumor Cells, Cultured

2002
Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells.
    Cancer letters, 2002, Sep-26, Volume: 183, Issue:2

    Topics: Antibiotics, Antineoplastic; Azacitidine; Breast Neoplasms; Chromatin; Decitabine; DNA Methylation; Down-Regulation; Drosophila Proteins; Enzyme Inhibitors; Fibroblasts; Histone Deacetylases; Humans; Hydroxamic Acids; Immunoblotting; Microscopy, Fluorescence; Promoter Regions, Genetic; Tropomyosin; Tumor Cells, Cultured

2002
Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.
    Oncogene, 2002, May-02, Volume: 21, Issue:19

    Topics: Animals; Azacitidine; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Drosophila melanogaster; Drosophila Proteins; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Kidney Neoplasms; Loss of Heterozygosity; Lung Neoplasms; Mutation, Missense; Nerve Tissue Proteins; Promoter Regions, Genetic; Receptors, Immunologic; Roundabout Proteins; Sequence Homology, Nucleic Acid; Tumor Cells, Cultured

2002
Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-15, Volume: 89, Issue:6

    Topics: Amino Acid Sequence; Antineoplastic Agents; Azacitidine; Base Sequence; Breast; Breast Neoplasms; Calcimycin; Calcium-Binding Proteins; Cell Cycle; Cell Line; Chromosome Banding; Decitabine; DNA; DNA Probes; DNA, Neoplasm; Female; Gene Expression; Humans; Molecular Sequence Data; Multigene Family; RNA; RNA, Messenger; RNA, Neoplasm; S100 Proteins; Sequence Homology, Nucleic Acid

1992
An evaluation of the putative human mammary tumour retrovirus associated with peripheral blood monocytes.
    British journal of cancer, 1991, Volume: 63, Issue:4

    Topics: Adult; Aged; Azacitidine; Breast Neoplasms; Cloning, Molecular; Female; Giant Cells; Humans; Microscopy, Electron; Middle Aged; Monocytes; Retroviridae; RNA-Directed DNA Polymerase; Tumor Cells, Cultured

1991
[Expression of antigens related to structural protein antigens of MMTV in breast cancer cells].
    Voprosy onkologii, 1985, Volume: 31, Issue:7

    Topics: Antigens, Neoplasm; Antigens, Viral; Azacitidine; Breast Neoplasms; Cell Line; Clone Cells; Dexamethasone; Estradiol; Female; Humans; Immunoenzyme Techniques; Mammary Tumor Virus, Mouse; Progesterone; Viral Proteins

1985
Alterations in the X chromosome replication pattern induced by 5-azacytidine in a human tumor line.
    Cancer genetics and cytogenetics, 1986, Feb-15, Volume: 20, Issue:3-4

    Topics: Azacitidine; Breast Neoplasms; Cell Line; Chromosome Banding; DNA Replication; Dosage Compensation, Genetic; Gene Expression Regulation; Humans; Methylation; X Chromosome

1986
Incorporation of 5-fluorodeoxycytidine and metabolites into nucleic acids of human MCF-7 breast carcinoma cells.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: Azacitidine; Breast Neoplasms; Cell Line; Cell Survival; Decitabine; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Floxuridine; Humans; Methylation; RNA, Neoplasm; Tetrahydrouridine

1986
[New cytostatics in oncological therapy].
    Deutsche medizinische Wochenschrift (1946), 1974, Nov-29, Volume: 99, Issue:48

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Chemical Phenomena; Chemistry; DNA Replication; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Lymphoma; Male; Mitolactol; Neoplasms; Nitrosourea Compounds; Testicular Neoplasms; Thyroid Neoplasms

1974