Compounds > azacitidine

azacitidine and Brain Neoplasms

azacitidine has been researched along with Brain Neoplasms in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.45)18.7374
1990's5 (8.06)18.2507
2000's20 (32.26)29.6817
2010's30 (48.39)24.3611
2020's3 (4.84)2.80

Authors

AuthorsStudies
Jaal, J; Laasfeld, T; Lavogina, D; Lust, H; Vardja, M1
da Costa Rosa, M; Riggins, GJ; Yamashita, AS1
Annereau, M; Bielle, F; Capelle, L; de Botton, S; Dehais, C; Delattre, JY; Federici, L; Hoang-Xuan, K; Idbaih, A; Laigle-Donadey, F; Lemare, F; Sanson, M; Touat, M; Willekens, C1
Jiang, Y; Jin, C; Li, M; Ouyang, Y; Tan, Z1
Bian, E; Guo, Z; Li, G; Ma, CC; Wan, J; Zhao, B1
Fichtner, I; Hanisch, UK; Hoffmann, J; Joedicke, A; Kratzsch, T; Kuhn, SA; Vajkoczy, P1
Davoudi, B; Ekström, TJ; Estekizadeh, A; Hu, LF; Landázuri, N; Nawaz, I; Pantalone, MR; Rahbar, A; Stragliotto, G1
Bai, Y; Bao, ZS; Chen, Y; Wang, LJ; Yan, ZH; Zhang, QG; Zhang, W1
Baia, GS; Baylin, SB; Borodovsky, A; Chan, TA; Eberhart, CG; Fabius, AW; Gallia, GL; Riggins, GJ; Salmasi, V; Turcan, S; Weingart, JD1
Borodovsky, A; Brennan, C; Chan, TA; Fabius, AW; Huse, J; Pedraza, A; Riggins, GJ; Turcan, S; Viale, A1
Geng, P; Liu, K; Yao, J; Zhang, J; Zhou, B; Zhu, W; Zhu, Y1
Chen, C; Deng, Q; Dong, X; Jia, W; Nie, X; Xu, C; Xu, R; Zhang, M1
Cui, Y; Irudayaraj, J; Naz, A; Thompson, DH1
Chakrabarti, M; Ray, SK1
Li, M; Sun, LG; Tian, XY; Zhang, L1
Beckhove, P; Gal, Z; Grabe, N; Herold-Mende, C; Lahrmann, B; Lasitschka, F; Mock, A; Mossemann, J; Schmezer, P; Schmoch, T; Unterberg, A1
Amankulor, N; Chan, T; Chang, Y; Choi, J; Deibert, C; Engh, J; Grandi, P; Kim, WJ; Kohanbash, G; Lotze, M; Okada, H; Park, Y; Pomerantz, A; Rao, A; Sette, P; Zhang, X1
Admon, A; Barnea, E; Kadosh, DM; Shraibman, B1
Barba, L; Bassoy, EY; Boehler, M; Calvo Tardón, M; Dietrich, PY; Jueliger, S; Marinari, E; Martinvalet, D; Pellegatta, S; Riccadonna, C; Taverna, P; Vuillefroy de Silly, R; Walker, PR; Yacoub Maroun, C1
Hu, G; Hu, L; Lu, Y; Ma, J; Meng, W; Wang, J; Zhang, C1
Ansari, M; Fallah, S; Ghasemi, A1
Ansari, KI; Chen, MY; Choy, C; Jandial, R; Levy, DM1
Aoyanagi, E; Kimura, T; Kohsaka, S; Nishihara, H; Sasai, K; Tabu, K; Tanaka, S; Tanino, M; Wang, L1
Ahuja, N; Baylin, SB; Costello, JF; Easwaran, H; Eberhart, CG; Glöckner, SC; Herman, JG; James, CD; Laterra, J; Lin, S; Ohm, JE; Riggins, G; Schuebel, KE; Tsai, HC; Vescovi, AL; Yi, JM1
Gu, Z; Horii, A; Inomata, K; Mitsui, H1
Ito, M; Kondo, Y; Maeda, Y; Natsume, A; Oi, S; Saito, K; Shimato, S; Wakabayashi, T1
Bian, X; Chen, K; Dunlop, NM; Gao, Y; Gong, W; Howard, OM; Huang, J; Wang, JM1
Gong, F; Ji, SP; Li, AM; Tai, JL; Zhang, YP; Zheng, CQ1
Jiao, H; Kere, J; Nistér, M; Qu, M; Ren, ZP; Smits, A; Zhao, J1
Hueng, DY; Jan, HJ; Lai, JH; Lee, CC; Lee, HM; Ma, HI; Shih, YL; Wei, HW1
Eling, TE; Kadowaki, M; Kamitani, H; Wade, PA; Watanabe, T; Yoshioka, H1
Borges, KS; Carlotti, CG; Gomes, MV; Machado, HR; Moreno, DA; Queiroz, RG; Scrideli, CA; Tone, LG1
Endl, E; Felsberg, J; Hammes, J; Hartmann, W; Pietsch, T; von dem Knesebeck, A; Waha, A1
Dam, MA; Eskin, A; Kim, W; Konkankit, VV; Koya, RC; Liau, LM; Nelson, S; Prins, RM; Ribas, A1
Adamson, DC; Bigner, D; Bortoff, K; Di, C; Duncan, C; Fu, J; Gregory, S; Killela, P; Lin, N; McLendon, R; Truszkowski, P1
Geng, J; Luo, H; Pu, Y; Wu, X; Xu, W; Yang, Z; Zhou, Z1
Bogiel, T; Carro, MS; Claus, R; Dai, F; Döbrössy, M; Doostkam, S; Firat, E; Herold-Mende, C; Kahlert, UD; Maciaczyk, D; Maciaczyk, J; Niedermann, G; Nikkhah, G; Prinz, M1
Bernaudin, M; Carlotti, CG; Carosella, ED; Donadi, EA; Ferrone, S; Flajollet, S; Jensen, SS; Kristensen, BW; Lechapt-Zalcman, E; Moreau, P; Pancoto, JT; Poras, I; Simões, RT; Valable, S; Wastowski, IJ; Yaghi, L1
Chan, AK; Lau, KM; Li, KK; Mao, Y; Ng, HK; Pang, JC; Poon, WS; Shi, Z; Wang, Y; Yang, L; Zhou, L1
Ali-Osman, F; Dinh, DH; Foster, DC; Gujrati, M; Kisiel, W; Kondraganti, S; Konduri, SD; Lakka, SS; Olivero, WC; Rao, JS; Srivenugopal, KS; Yanamandra, N1
Horiguchi, K; Ishiuchi, S; Kurihara, H; Mori, M; Saito, N; Tomizawa, Y; Tosaka, M1
Black, KL; Liu, G; Wheeler, CJ; Ying, H; Yu, JS; Zeng, G1
Gu, J; Li, J; Lin, S; Lu, W; Wang, Y; Yu, J; Zhang, H; Zhu, J1
Frühwald, MC; Grotzer, M; Hagemann, C; Jürgens, H; Mühlisch, J; Osada, N; Rickert, CH; Roggendorf, W; Schwering, A; Sörensen, N; Vince, GH1
Fahey, J; Field, L; Foltz, G; Frakes, A; Hood, L; Lee, H; Madan, A; Nelson, T; Ryken, TC; Ryu, GY; Sibenaller, Z; Vibhakar, R; Yoon, JG; Zander, K1
Blaschke, B; Knobbe, CB; Reifenberger, G; van den Boom, J; Wolter, M1
Fields, CR; Kim, JH; Kim, TY; Robertson, KD; Zhong, S1
Albert, SH; Liao, D; Liu, J; Niu, Y; Robertson, KD; Santiago, A; Zhao, LY1
Hu, J; Jiang, Y; Jiang, Z; Li, G; Li, X; Lu, D; Zhou, W1
Casartelli, C; De Campos, JM; Franco-Hernandez, C; Gonzalez-Gomez, P; Gutierrez, M; Isla, A; Martinez-Glez, V; Rey, JA; Vaquero, J1
Betz, B; Ehrentraut, D; Felsberg, J; Hampl, JA; Hellmich, M; Köhler, J; Mikeska, T; Niederacher, D; Pietsch, T; Röhn, G; Schmutzler, RK; Versmold, B; Waha, A1
Lea, R; Patel, R; Shervington, A; Shervington, L1
Ito, M; Kawatsura, H; Kondo, Y; Kuzushima, K; Narita, Y; Natsume, A; Sekido, Y; Shimato, S; Tsujimura, K; Wakabayashi, T; Yoshida, J1
Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM1
Chabot, GG; Momparler, RL1
Augusti-Tocco, G; Bartolucci, S; Carpinelli, P; Granata, F; Rossi, M1
Eyre, HJ; Selby, GB; Townsend, J; Upchurch, C1
Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D1
Berger, MS; Cavenee, WK; Costello, JF; Huang, HS1
Bachman, KE; Baylin, SB; Cavenee, WK; Corn, PG; Costello, JF; Graff, JR; Herman, JG; Merlo, A1
Bigner, DD; Friedman, HS; Schold, SC1
Driscoll, JS; Johns, DG; Plowman, J1

Trials

1 trial(s) available for azacitidine and Brain Neoplasms

ArticleYear
A phase II evaluation of fazarabine in high-grade gliomas: a Southwest Oncology Group study.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Azacitidine; Brain Neoplasms; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Southwestern United States; Treatment Failure

1994

Other Studies

61 other study(ies) available for azacitidine and Brain Neoplasms

ArticleYear
Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets.
    Scientific reports, 2021, 10-13, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Lomustine; Temozolomide

2021
Evaluation of a DNA demethylating agent in combination with all-trans retinoic acid for IDH1-mutant gliomas.
    Neuro-oncology, 2022, 05-04, Volume: 24, Issue:5

    Topics: Animals; Azacitidine; Brain Neoplasms; DNA Methylation; Glioma; Humans; Isocitrate Dehydrogenase; Mice; Mutation; Tretinoin

2022
5-Azacitidine in patients with IDH1/2-mutant recurrent glioma.
    Neuro-oncology, 2020, 08-17, Volume: 22, Issue:8

    Topics: Adult; Aged; Azacitidine; Brain Neoplasms; Female; Glioma; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Mutation

2020
MiR-424 functions as a tumor suppressor in glioma cells and is down-regulated by DNA methylation.
    Journal of neuro-oncology, 2017, Volume: 133, Issue:2

    Topics: Adult; Aged; Apoptosis; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Humans; MicroRNAs; Middle Aged; Oligodeoxyribonucleotides, Antisense; Time Factors; Transduction, Genetic

2017
TGF-β-mediated repression of MST1 by DNMT1 promotes glioma malignancy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 94

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioma; Hepatocyte Growth Factor; Humans; Neoplasm Invasiveness; Proto-Oncogene Proteins; Transforming Growth Factor beta; Up-Regulation

2017
Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas.
    Journal of cancer research and clinical oncology, 2018, Volume: 144, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Glioblastoma; Humans; Mice, Inbred NOD; Mice, Knockout; Mice, Nude; Mice, SCID; Tumor Burden; Xenograft Model Antitumor Assays

2018
5‑Azacytidine treatment results in nuclear exclusion of DNA methyltransferase‑1, as well as reduced proliferation and invasion in human cytomegalovirus‑infected glioblastoma cells.
    Oncology reports, 2019, Volume: 41, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cytomegalovirus; Cytoplasm; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Female; Glioblastoma; Humans; Male; Middle Aged; Treatment Outcome; Viral Envelope Proteins; Virus Replication

2019
Hypermethylation of testis derived transcript gene promoter significantly correlates with worse outcomes in glioblastoma patients.
    Chinese medical journal, 2013, Volume: 126, Issue:11

    Topics: Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cytoskeletal Proteins; Decitabine; DNA Methylation; Glioblastoma; Humans; LIM Domain Proteins; Promoter Regions, Genetic; RNA-Binding Proteins; Treatment Outcome

2013
5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft.
    Oncotarget, 2013, Volume: 4, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; DNA Methylation; Female; Glioma; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Male; Mice; Mice, Nude; Mutation; Xenograft Model Antitumor Assays

2013
Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.
    Oncotarget, 2013, Volume: 4, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; Cell Differentiation; Cell Growth Processes; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Glioma; Heterografts; Humans; Isocitrate Dehydrogenase; Mice; Mice, SCID; Mutation

2013
A new tumor suppressor LncRNA ADAMTS9-AS2 is regulated by DNMT1 and inhibits migration of glioma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:8

    Topics: ADAM Proteins; ADAMTS9 Protein; Adult; Aged; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Invasiveness; RNA, Antisense; RNA, Long Noncoding; RNA, Small Interfering; Tumor Suppressor Proteins

2014
Downregulation of HTATIP2 expression is associated with promoter methylation and poor prognosis in glioma.
    Experimental and molecular pathology, 2015, Volume: 98, Issue:2

    Topics: Acetyltransferases; Antimetabolites, Antineoplastic; Azacitidine; Binding Sites; Brain Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; HEK293 Cells; Humans; Male; Middle Aged; Prognosis; Promoter Regions, Genetic; Sp1 Transcription Factor; Transcription Factors

2015
Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomide.
    Molecular pharmaceutics, 2015, Apr-06, Volume: 12, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Azacitidine; Biocompatible Materials; Boron Compounds; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Decitabine; DNA Methylation; Drug Delivery Systems; Drug Synergism; Glioblastoma; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Methacrylates; Methylmethacrylates; Micelles; Nanoconjugates; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence; Temozolomide

2015
Direct transfection of miR-137 mimics is more effective than DNA demethylation of miR-137 promoter to augment anti-tumor mechanisms of delphinidin in human glioblastoma U87MG and LN18 cells.
    Gene, 2015, Nov-15, Volume: 573, Issue:1

    Topics: Anthocyanins; Azacitidine; Brain Neoplasms; Cell Division; Cell Line, Tumor; DNA Methylation; Glioblastoma; Humans; MicroRNAs; Promoter Regions, Genetic; Transfection

2015
Epigenetic Regulation of miR-129-2 Leads to Overexpression of PDGFRa and FoxP1 in Glioma Cells.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:14

    Topics: Adult; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Brain Neoplasms; Cell Proliferation; Chromatin Assembly and Disassembly; Decitabine; DNA Methylation; Epigenesis, Genetic; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Glioma; Humans; MicroRNAs; Real-Time Polymerase Chain Reaction; Receptor, Platelet-Derived Growth Factor alpha; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

2015
Combined Treatment of ATRA with Epigenetic Drugs Increases Aggressiveness of Glioma Xenografts.
    Anticancer research, 2016, Volume: 36, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Epigenomics; Female; Glioma; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice, Inbred NOD; Mice, SCID; Tretinoin; Tumor Burden; Vorinostat; Xenograft Model Antitumor Assays

2016
IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression.
    Neuro-oncology, 2016, Volume: 18, Issue:10

    Topics: Antineoplastic Agents; Azacitidine; Brain Neoplasms; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; GPI-Linked Proteins; Humans; Immunologic Surveillance; Intercellular Signaling Peptides and Proteins; Isocitrate Dehydrogenase; Killer Cells, Natural; Mutation; Real-Time Polymerase Chain Reaction; Transcriptome; Tumor Escape

2016
Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:9

    Topics: Antigens, Neoplasm; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; HLA Antigens; Humans; Immunotherapy; Peptides; Proteomics; Sequence Analysis, RNA

2016
Decitabine Treatment of Glioma-Initiating Cells Enhances Immune Recognition and Killing.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Animals; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; Fas Ligand Protein; fas Receptor; Gene Expression Regulation, Neoplastic; Genes, MHC Class I; Glioma; Humans; Intercellular Adhesion Molecule-1; Mice; Neoplastic Stem Cells; T-Lymphocytes, Cytotoxic; Up-Regulation; Xenograft Model Antitumor Assays

2016
Methylation Status of the RIZ1 Gene Promoter in Human Glioma Tissues and Cell Lines.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:6

    Topics: Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Glioma; Histone-Lysine N-Methyltransferase; Humans; Male; Middle Aged; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors

2017
MicroRNA-149 is epigenetically silenced tumor-suppressive microRNA, involved in cell proliferation and downregulation of AKT1 and cyclin D1 in human glioblastoma multiforme.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2016, Volume: 94, Issue:6

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Base Sequence; Brain; Brain Neoplasms; Cell Proliferation; Cyclin D1; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; MicroRNAs; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured

2016
Astrocyte-induced Reelin expression drives proliferation of Her2
    Clinical & experimental metastasis, 2017, Volume: 34, Issue:2

    Topics: Astrocytes; Azacitidine; Brain Neoplasms; Breast Neoplasms; Cell Adhesion Molecules, Neuronal; Cell Division; Coculture Techniques; Culture Media, Serum-Free; DNA Methylation; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Nerve Tissue Proteins; Receptor, ErbB-2; Reelin Protein; RNA Interference; RNA, Small Interfering; Serine Endopeptidases; Spheroids, Cellular; Transcriptional Activation; Triple Negative Breast Neoplasms; Tumor Cells, Cultured

2017
Promoter hypomethylation regulates CD133 expression in human gliomas.
    Cell research, 2008, Volume: 18, Issue:10

    Topics: 5' Untranslated Regions; AC133 Antigen; Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; Humans; Peptides; Promoter Regions, Genetic; Tumor Cells, Cultured

2008
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
    Cancer research, 2008, Oct-01, Volume: 68, Issue:19

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents; Azacitidine; Brain Neoplasms; Caco-2 Cells; Carcinoma; Colorectal Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Peptides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2008
Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas.
    Genes & genetic systems, 2008, Volume: 83, Issue:4

    Topics: Azacitidine; Base Sequence; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; DNA Methylation; DNA Mutational Analysis; Enzyme Inhibitors; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Humans; Hydroxamic Acids; Isoenzymes; Molecular Sequence Data; Promoter Regions, Genetic; Ubiquitin-Protein Ligases

2008
Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Antigens, Neoplasm; Azacitidine; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Gene Expression; Glioma; Histone Deacetylase Inhibitors; Histones; Humans; Immunotherapy; Membrane Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Valproic Acid

2009
Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation.
    Carcinogenesis, 2009, Volume: 30, Issue:2

    Topics: Animals; Azacitidine; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chemotaxis; Decitabine; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methylation; Mice; Mice, Nude; Neoplasm Transplantation; Promoter Regions, Genetic; Receptors, Formyl Peptide; Transplantation, Heterologous; Tumor Suppressor Protein p53

2009
[Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azacitidine; Brain Neoplasms; Cell Line, Tumor; CpG Islands; Dacarbazine; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Glioma; Humans; Male; Middle Aged; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Promoter Regions, Genetic; Survival Rate; Temozolomide; Young Adult

2009
Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas.
    Neuropathology and applied neurobiology, 2010, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Aged; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Child; Child, Preschool; Chromosomes, Human, Pair 19; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Genes, Tumor Suppressor; Glioma; Humans; Loss of Heterozygosity; Male; Middle Aged; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Young Adult

2010
Osteopontin regulates human glioma cell invasiveness and tumor growth in mice.
    Neuro-oncology, 2010, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Decitabine; Electrophoresis, Polyacrylamide Gel; Glioma; Humans; Immunohistochemistry; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neoplasm Invasiveness; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; Vimentin; Xenograft Model Antitumor Assays

2010
DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines.
    International journal of cancer, 2012, Jan-15, Volume: 130, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azacitidine; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Decitabine; DNA Methylation; Early Growth Response Protein 1; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Growth Differentiation Factor 15; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Sulindac; Transfection

2012
Abnormal methylation of histone deacetylase genes: implications on etiology and epigenetic therapy of astrocytomas.
    Anticancer research, 2011, Volume: 31, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Astrocytoma; Azacitidine; Brain; Brain Neoplasms; Child; Colony-Forming Units Assay; Decitabine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Histone Deacetylase 6; Histone Deacetylases; Humans; Polymerase Chain Reaction; Repressor Proteins; Tumor Cells, Cultured

2011
Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas.
    International journal of cancer, 2012, Aug-01, Volume: 131, Issue:3

    Topics: 5' Untranslated Regions; Apoptosis; Astrocytoma; Azacitidine; Base Sequence; Brain Neoplasms; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Exons; Gene Expression Regulation, Neoplastic; Humans; Neuroendocrine Secretory Protein 7B2; Promoter Regions, Genetic; Sequence Analysis, DNA; Transcription, Genetic

2012
Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.
    Journal of translational medicine, 2011, Nov-07, Volume: 9

    Topics: Antigens, Neoplasm; Azacitidine; Brain Neoplasms; Cell Death; Cell Line, Tumor; Coculture Techniques; Cytokines; Decitabine; Fas Ligand Protein; fas Receptor; Glioma; Histocompatibility Antigens Class I; Humans; Membrane Proteins; Molecular Targeted Therapy; Retroviridae; Signal Transduction; T-Lymphocytes; Transduction, Genetic; Up-Regulation

2011
Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma.
    Molecular cancer research : MCR, 2012, Volume: 10, Issue:2

    Topics: Azacitidine; Brain Neoplasms; Cell Adhesion Molecules; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; RNA, Small Interfering

2012
Methylation mediated silencing of miR-23b expression and its role in glioma stem cells.
    Neuroscience letters, 2012, Oct-24, Volume: 528, Issue:2

    Topics: Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Decitabine; Down-Regulation; Epigenesis, Genetic; Gene Silencing; Glioma; Humans; Methylation; MicroRNAs; Neoplastic Stem Cells; Promoter Regions, Genetic; Temozolomide

2012
Resistance to hypoxia-induced, BNIP3-mediated cell death contributes to an increase in a CD133-positive cell population in human glioblastomas in vitro.
    Journal of neuropathology and experimental neurology, 2012, Volume: 71, Issue:12

    Topics: AC133 Antigen; Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; Cell Death; Cell Hypoxia; Cell Line; Cell Proliferation; Chromatin Immunoprecipitation; DNA Methylation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; Humans; Membrane Proteins; Peptides; Proto-Oncogene Proteins; Signal Transduction; Transfection

2012
Human leukocyte antigen-G is frequently expressed in glioblastoma and may be induced in vitro by combined 5-aza-2'-deoxycytidine and interferon-γ treatments: results from a multicentric study.
    The American journal of pathology, 2013, Volume: 182, Issue:2

    Topics: Acetylation; Aged; Antigen Presentation; Azacitidine; beta 2-Microglobulin; Biopsy; Brain Neoplasms; Cell Line, Tumor; Chromatin Assembly and Disassembly; Decitabine; DNA Methylation; Female; Glioblastoma; HLA-G Antigens; Humans; Interferon-gamma; Male; Middle Aged; Paraffin Embedding; Prognosis; Promoter Regions, Genetic; Survival Analysis; Transcription, Genetic; Up-Regulation

2013
MIR-137 suppresses growth and invasion, is downregulated in oligodendroglial tumors and targets CSE1L.
    Brain pathology (Zurich, Switzerland), 2013, Volume: 23, Issue:4

    Topics: Adult; Aged; Azacitidine; Brain Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Cellular Apoptosis Susceptibility Protein; Child; Cohort Studies; Collagen; Decitabine; Down-Regulation; Drug Combinations; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Kaplan-Meier Estimate; Laminin; Male; MicroRNAs; Middle Aged; Oligodendroglioma; Proteoglycans

2013
Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
    Oncogene, 2003, Jul-17, Volume: 22, Issue:29

    Topics: Azacitidine; Brain Neoplasms; Chromatin; Chromosomal Proteins, Non-Histone; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme Inhibitors; Gene Silencing; Glioblastoma; Glioma; Glycoproteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Methyl-CpG-Binding Protein 2; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins

2003
Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors.
    Oncogene, 2003, Oct-30, Volume: 22, Issue:49

    Topics: Azacitidine; Brain Neoplasms; Cell Line, Tumor; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; Genes, Tumor Suppressor; Glioma; Humans; Medulloblastoma; Neoplasm Proteins; Promoter Regions, Genetic; Tumor Suppressor Proteins

2003
HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells.
    Cancer research, 2004, Jul-15, Volume: 64, Issue:14

    Topics: Animals; Antigen Presentation; Antigens, Neoplasm; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Decitabine; DNA Methylation; Epitopes, T-Lymphocyte; Gene Expression Regulation, Neoplastic; Glioblastoma; gp100 Melanoma Antigen; Humans; Interferon-gamma; Melanoma-Specific Antigens; Membrane Glycoproteins; Neoplasm Proteins; Receptor, ErbB-2; RNA, Messenger; T-Lymphocytes, Cytotoxic

2004
Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma.
    BMC cancer, 2004, Sep-14, Volume: 4

    Topics: Adolescent; Adult; Antigens, Neoplasm; Astrocytoma; Azacitidine; Brain Neoplasms; Cadherins; Carcinoma, Hepatocellular; Child; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Genes, Tumor Suppressor; Glioma; Humans; Liver Neoplasms; Male; Melanoma-Specific Antigens; Middle Aged; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Sex Factors; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Proteins

2004
Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood.
    Oncogene, 2006, Feb-16, Volume: 25, Issue:7

    Topics: Adolescent; Adult; Azacitidine; Brain Neoplasms; Caspase 8; Caspases; Child; Child, Preschool; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Silencing; Humans; Hydroxamic Acids; Infant; Male; Neuroectodermal Tumors, Primitive; Promoter Regions, Genetic; Rhabdoid Tumor; Teratoma; Tumor Suppressor Proteins

2006
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.
    Cancer research, 2006, Jul-01, Volume: 66, Issue:13

    Topics: Azacitidine; Brain Neoplasms; Decitabine; DNA Methylation; Gene Expression; Gene Expression Profiling; Gene Silencing; Genes, Tumor Suppressor; Genome, Human; Glioma; Histones; Humans; Hydroxamic Acids; Nerve Tissue Proteins; Promoter Regions, Genetic

2006
Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction.
    International journal of cancer, 2006, Nov-15, Volume: 119, Issue:10

    Topics: Adenosine Triphosphatases; Antimetabolites, Antineoplastic; Apolipoproteins; Apolipoproteins D; Astrocytoma; Azacitidine; Biomarkers, Tumor; Brain Neoplasms; Cation Transport Proteins; Cell Adhesion Molecules, Neuronal; Decitabine; Disease Progression; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Glycoproteins; Guanine Nucleotide Exchange Factors; Histone Deacetylases; Humans; Hydroxamic Acids; Membrane Transport Proteins; Nerve Tissue Proteins; Nuclear Proteins; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; Proteins; Reverse Transcriptase Polymerase Chain Reaction

2006
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.
    Cancer research, 2006, Aug-01, Volume: 66, Issue:15

    Topics: Azacitidine; Brain Neoplasms; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Humans; Hydroxamic Acids; Up-Regulation

2006
An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis.
    Cancer research, 2006, Oct-01, Volume: 66, Issue:19

    Topics: Apoptosis; Azacitidine; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Chromosomes, Human, Pair 10; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Male; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplasms; Promoter Regions, Genetic; Recombinant Fusion Proteins; Transcription, Genetic

2006
Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma.
    Neuroscience research, 2006, Volume: 56, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Apoptosis; Astrocytoma; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Dealkylation; DNA; Down-Regulation; Female; Flow Cytometry; Humans; Male; Methylation; Middle Aged; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfates; Tumor Suppressor Proteins

2006
DAPK1 promoter hypermethylaiton in brain metastases and peripheral blood.
    Neoplasma, 2007, Volume: 54, Issue:2

    Topics: Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Azacitidine; Biomarkers, Tumor; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; CpG Islands; Death-Associated Protein Kinases; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Promoter Regions, Genetic

2007
Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer.
    International journal of cancer, 2007, Aug-01, Volume: 121, Issue:3

    Topics: Adult; Aged; Azacitidine; Brain Neoplasms; Breast Neoplasms; CpG Islands; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Homeodomain Proteins; Humans; Middle Aged; Oligonucleotide Array Sequence Analysis; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins

2007
Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma.
    Brain research, 2008, Jan-10, Volume: 1188

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cellular Senescence; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioma; Humans; Methyltransferases; Paclitaxel; RNA, Messenger; Telomerase

2008
The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma.
    International journal of cancer, 2008, Jun-01, Volume: 122, Issue:11

    Topics: Adoptive Transfer; Analysis of Variance; Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Asian People; Azacitidine; Blotting, Western; Brain Neoplasms; Chromosome Mapping; CpG Islands; Decitabine; DNA Methylation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioma; Histocompatibility Antigens Class I; Humans; Kaplan-Meier Estimate; Male; Membrane Proteins; Mice; Mice, Inbred NOD; Mice, SCID; Microarray Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Cytotoxic; Testis; Transplantation, Heterologous; Up-Regulation

2008
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
    Nucleic acids research, 1983, Jan-25, Volume: 11, Issue:2

    Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin

1983
Antileukemic activity of 5-aza-2'-deoxycytidine and cytarabine against intracerebral L1210 murine leukemia.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Animals; Azacitidine; Brain Neoplasms; Cytarabine; Decitabine; Dose-Response Relationship, Drug; Kinetics; Leukemia L1210; Male; Mice; Mice, Inbred Strains

1984
Antiproliferative effects and DNA hypomethylation by 5-aza-2'-deoxycytidine in human neuroblastoma cell lines.
    Anti-cancer drugs, 1993, Volume: 4, Issue:6

    Topics: Antigens, Differentiation; Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Division; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA-Cytosine Methylases; DNA, Neoplasm; Humans; Methylation; Neuroblastoma; Tumor Cells, Cultured

1993
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
    Nature medicine, 1995, Volume: 1, Issue:7

    Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured

1995
Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation.
    Cancer research, 1996, May-15, Volume: 56, Issue:10

    Topics: Astrocytoma; Azacitidine; Base Sequence; Brain Chemistry; Brain Neoplasms; Carrier Proteins; Chromatin; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; Molecular Sequence Data; Neoplasm Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

1996
Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers.
    Cancer research, 1999, Feb-15, Volume: 59, Issue:4

    Topics: Azacitidine; Brain Neoplasms; CpG Islands; Decitabine; DNA Methylation; Humans; Kidney Neoplasms; Tissue Inhibitor of Metalloproteinase-3

1999
Chemotherapy of subcutaneous and intracranial human medulloblastoma xenografts in athymic nude mice.
    Cancer research, 1986, Volume: 46, Issue:1

    Topics: Animals; Azacitidine; Brain Neoplasms; Cell Line; Cytarabine; Doxorubicin; Humans; Medulloblastoma; Melphalan; Mice; Mice, Nude; Mitoguazone; Neoplasm Transplantation; Nitrosourea Compounds; Skin Neoplasms; Vidarabine Phosphate

1986
Comparison of the activity of arabinosyl-5-azacytosine, arabinosyl cytosine, and 5-azacytidine against intracerebrally implanted L1210 leukemia.
    Investigational new drugs, 1985, Volume: 3, Issue:4

    Topics: Animals; Antineoplastic Agents; Azacitidine; Brain Neoplasms; Carmustine; Cytarabine; Leukemia L1210; Mice; Mice, Inbred Strains; Neoplasm Transplantation

1985