azacitidine and Blast Crisis

azacitidine has been researched along with Blast Crisis in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (21.88)18.2507
2000's3 (9.38)29.6817
2010's18 (56.25)24.3611
2020's4 (12.50)2.80

Authors

AuthorsStudies
Hu, Y; Huang, P; Li, J; Liu, C; Liu, H; Liu, Q; Wang, Y; Wu, L; Yang, Z; Zheng, Y1
Bobin, A; Cayssials E, E; Chomel, JC; Desmier, D; Gallego-Hernanz, P; Gardeney, H; Maillard, N; Moya, N; Systchenko, T; Torregrosa, J; Vonfeld, M1
Garcia-Horton, A; Gupta, V; Maze, D; McNamara, CJ; Murphy, T; Sibai, H1
Al-Kali, A; Alkhateeb, H; Begna, KH; Elliott, MA; Foran, JM; Gangat, N; Guglielmelli, P; Hanson, CA; Litzow, MR; Mannelli, F; Palmer, JM; Pardanani, A; Patnaik, MM; Szuber, N; Tefferi, A; Vannucchi, AM1
Comerford, CM; Langabeer, SE; Murphy, PT; Quinn, J1
Bertsch, HP; Claßen, A; Kitz, J; Lippert, U; Overbeck, T; Perske, C; Schön, MP1
Füreder, W; Gleixner, K; Grünberger, B; Hoermann, G; Kornauth, C; Schwarzinger, I; Sperr, WR; Thalhammer, R; Valent, P1
Berthou, C; Boyer-Perrard, F; Chauveau, A; Couturier, MA; Dagorne, A; Douet-Guilbert, N; Guillerm, G; Houot, R; Hunault, M; Ianotto, JC; Le Calloch, R; Lippert, É; Luycx, O; Malou, M; Mollard, LM; Quintin-Roué, I; Thepot, S; Ugo, V1
Anaclerico, B; Andriani, A; Aroldi, A; Breccia, M; Carmosino, I; Centra, A; Di Veroli, A; Elli, E; Fianchi, L; Foà, R; Latagliata, R; Martini, V; Montanaro, G; Montanaro, M; Niscola, P; Trapè, G; Villivà, N; Voso, MT1
Auger, N; Bennaceur-Griscelli, A; Bourhis, JH; Castaigne, S; de Botton, S; Ghez, D; Ianotto, JC; Micol, JB; Pasquier, F; Rigaudeau, S; Rousselot, P; Saada, V; Spentchian, M; Terré, C1
Galli, S; Harrison, CN; Keohane, C; McLornan, DP; Mwirigi, A; Radia, DH; Raj, K1
Adès, L; Berthon, C; Bouscary, D; Caillot, D; Cluzeau, T; Dartigeas, C; Delaunay, J; Devidas, A; Dombret, H; Fenaux, P; Gardin, C; Guièze, R; Ifrah, N; Itzykson, R; Marolleau, JP; Plantier, I; Prébet, T; Recher, C; Stamatoullas, A; Taksin, AL; Thépot, S; Turlure, P; Vey, N1
Al-Ali, HK; Beach, CL; Bernal del Castillo, T; Butrym, A; Candoni, A; Cavenagh, J; Döhner, H; Dombret, H; Falantes, J; Jang, JH; Kumar, R; Lucy, LM; Martinelli, G; McIntyre, H; Minden, MD; Noppeney, R; Récher, C; Sandhu, I; Schuh, AC; Selleslag, D; Seymour, JF; Songer, S; Stone, RM; Wierzbowska, A1
Alimena, G; Andriani, A; Andrizzi, C; Ciccone, F; De Gregoris, C; Di Veroli, A; Latagliata, R; Maurillo, L; Montanaro, M; Villivà, N; Voso, MT1
Berthon, C; Delaunay, J; Dreyfus, F; Esterni, B; Fenaux, P; Itzykson, R; Kulasekararaj, A; Micol, JB; Mufti, G; Prebet, T; Recher, C; Roux, C; Sebert, M; Thepot, S; Vey, N; Wanquet, A1
Badar, T; Borthakur, G; Cortes, JE; Daver, N; Jabbour, E; Kantarjian, HM; Newberry, KJ; Pemmaraju, N; Pierce, SR; Ravandi, F; Verstovsek, S1
Huls, G1
Aul, C; Baron, F; Becker, H; de Witte, T; Fiaccadori, V; Ganser, A; Germing, U; Giagounidis, A; Hagemeijer, A; Labar, B; Lübbert, M; Muus, P; Pflüger, KH; Platzbecker, U; Rüter, BH; Salih, HR; Schaefer, HE; Selleslag, D; Suciu, S; Wijermans, PW1
Aoyama, K; Choi, K; Hasegawa, N; Iseki, T; Isshiki, Y; Iwama, A; Kawajiri-Manako, C; Koide, S; Mimura, N; Muto, T; Nagao, Y; Nakaseko, C; Ohwada, C; Sakai, S; Sakaida, E; Shimizu, R; Starczynowski, DT; Takeda, Y; Takeuchi, M; Togasaki, E; Tsukamoto, S; Yokote, K1
Backstrom, J; Beach, CL; Dombret, H; Fenaux, P; Gattermann, N; Germing, U; Gore, S; Hellström-Lindberg, E; List, AF; McKenzie, D; Mufti, GJ; Santini, V; Sanz, G; Seymour, JF; Silverman, LR; Zimmerman, L1
Leary, C; Lowery-Nordberg, M; Stephens, J; Turturro, F; Veillon, D1
Bhatla, T; Brown, P; Burke, MJ; Carroll, WL; Morrison, DJ; Raetz, EA; Wang, J1
Andreeff, M; Cortes, J; Faderl, S; Garcia-Manero, G; Giles, FJ; Issa, JP; Kantarjian, HM; Keating, M; O'Brien, S; Rios, MB; Shan, J; Talpaz, M1
Chang, JG; Chen, YH; Hsiao, HH; Lin, HY; Lin, PM; Lin, SF; Liu, TC; Liu, YC; Tang, KP; Yang, MY1
Cortes, J; Garcia-Manero, G; Gharibyan, V; Issa, JP; Jones, D; Kantarjian, HM; Morris, GM; O'brien, S; Oki, Y; Verstovsek, S1
Bennett, J; Browman, G; Bryant, J; Goldberg, J; Grunwald, H; Gryn, J; Larson, R; Preisler, H; Raza, A; Vogler, R1
Catapano, CV; Colombo, T; Conter, V; Damia, G; Gervasoni, M; Giudici, G; Limonta, M; Liso, V; Masera, G; Specchia, G1
Beran, M; de Vos, D; Estey, E; Giralt, S; Kantarjian, HM; Keating, M; Kornblau, S; O'Brien, SM; Rios, MB; Talpaz, M1
Estey, E; Kantarjian, HM; Keating, MJ; O'Brien, S; Plunkett, W; Rios, MB; Sorenson, M; Wilhelm, M1
Beran, M; Cortes, J; Giles, FJ; Kantarjian, HM; Keating, MJ; Koller, CA; O'Brien, S; Rios, MB; Sacchi, S; Talpaz, M1
Arlin, Z; Bennett, JM; Dutcher, JP; Eudey, L; Kellermeyer, R; O'Connell, M; Oken, M; Paietta, E; Rowe, J; Wiernik, PH1
McCulloch, EA; Yang, GS1

Trials

10 trial(s) available for azacitidine and Blast Crisis

ArticleYear
Azacitidine for the treatment of relapsed and refractory AML in older patients.
    Leukemia research, 2015, Volume: 39, Issue:2

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Retrospective Studies; Risk Factors; Survival Rate

2015
International phase 3 study of azacitidine vs conventional care regimens in older patients with newly diagnosed AML with >30% blasts.
    Blood, 2015, Jul-16, Volume: 126, Issue:3

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Female; Follow-Up Studies; Humans; International Agencies; Leukemia, Myeloid, Acute; Male; Neoplasm Staging; Prognosis; Prospective Studies; Survival Rate

2015
Decitabine versus best supportive care in older patients with refractory anemia with excess blasts in transformation (RAEBt) - results of a subgroup analysis of the randomized phase III study 06011 of the EORTC Leukemia Cooperative Group and German MDS St
    Annals of hematology, 2015, Volume: 94, Issue:12

    Topics: Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Decitabine; Disease-Free Survival; Female; Humans; Male; Middle Aged; Survival Rate

2015
Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Feb-01, Volume: 28, Issue:4

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Bone Marrow Cells; Female; Follow-Up Studies; Humans; International Agencies; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Prognosis; Survival Rate; Treatment Outcome

2010
Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia.
    Blood, 2012, May-31, Volume: 119, Issue:22

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Cell Line, Tumor; Child; Child, Preschool; Cohort Studies; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Leukemic; Gene Silencing; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Leukemia, B-Cell; Male; Vorinostat

2012
Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia.
    Cancer, 2007, Mar-01, Volume: 109, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzamides; Blast Crisis; Decitabine; DNA Methylation; Female; Genes, abl; Humans; Imatinib Mesylate; Male; Middle Aged; Piperazines; Polymerase Chain Reaction; Pyrimidines; Survival Analysis; Treatment Outcome

2007
Mitoxantrone and 5-azacytidine for refractory/relapsed ANLL or CML in blast crisis: a leukemia intergroup study.
    American journal of hematology, 1993, Volume: 43, Issue:4

    Topics: Adult; Azacitidine; Biopsy; Blast Crisis; Bone Marrow; Cell Cycle; DNA, Neoplasm; Female; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Outcome Assessment, Health Care; Recurrence

1993
Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia.
    Leukemia, 1997, Volume: 11, Issue:10

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Decitabine; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Accelerated Phase; Male; Middle Aged

1997
Phase I study of arabinosyl-5-azacytidine (fazarabine) in adult acute leukemia and chronic myelogenous leukemia in blastic phase.
    Leukemia & lymphoma, 1999, Volume: 34, Issue:5-6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Azacitidine; Blast Crisis; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Salvage Therapy; Treatment Outcome

1999
Phase II study of mitoxantrone and 5-azacytidine for accelerated and blast crisis of chronic myelogenous leukemia: a study of the Eastern Cooperative Oncology Group.
    Leukemia, 1992, Volume: 6, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Drug Evaluation; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Accelerated Phase; Male; Middle Aged; Mitoxantrone; Remission Induction

1992

Other Studies

22 other study(ies) available for azacitidine and Blast Crisis

ArticleYear
Tyrosine kinase inhibitors combined with venetoclax and azacytidine as an effective therapy for de novo lymphoid blast phase-chronic myeloid leukemia.
    Leukemia research, 2023, Volume: 127

    Topics: Azacitidine; Blast Crisis; Bridged Bicyclo Compounds, Heterocyclic; Fusion Proteins, bcr-abl; Humans; Protein Kinase Inhibitors; Tyrosine Kinase Inhibitors

2023
Combination of azacitidine, venetoclax and ruxolitinib in blast phase myeloproliferative neoplasms.
    British journal of haematology, 2023, Volume: 202, Issue:2

    Topics: Aged; Aged, 80 and over; Azacitidine; Blast Crisis; Humans; Myeloproliferative Disorders; Quality of Life; Treatment Outcome

2023
Azacitidine and venetoclax for the treatment of accelerated and blast phase myeloproliferative neoplasms and chronic myelomonocytic leukemia: a case series.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:6

    Topics: Azacitidine; Blast Crisis; Bridged Bicyclo Compounds, Heterocyclic; Humans; Leukemia, Myelomonocytic, Chronic; Sulfonamides

2021
Venetoclax with azacitidine or decitabine in blast-phase myeloproliferative neoplasm: A multicenter series of 32 consecutive cases.
    American journal of hematology, 2021, 07-01, Volume: 96, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Bridged Bicyclo Compounds, Heterocyclic; Decitabine; Female; Humans; Male; Middle Aged; Myeloproliferative Disorders; Retrospective Studies; Sulfonamides; Survival Analysis; Treatment Outcome

2021
Molecular profiling and targeted inhibitor therapy in atypical chronic myeloid leukaemia in blast crisis.
    Journal of clinical pathology, 2017, Volume: 70, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; DNA Mutational Analysis; High-Throughput Nucleotide Sequencing; Humans; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Male; Middle Aged; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Sorafenib

2017
Leukemia cutis in a patient with chronic myelomonocytic leukemia.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2018, Volume: 16, Issue:1

    Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Diagnosis, Differential; Humans; Leukemia, Myelomonocytic, Chronic; Leukemic Infiltration; Male; Skin

2018
Major response of PNH to an AML chemotherapy protocol.
    Annals of hematology, 2018, Volume: 97, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Cytarabine; Daunorubicin; Hemoglobinuria, Paroxysmal; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction

2018
Outcome of Ph negative myeloproliferative neoplasms transforming to accelerated or leukemic phase.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Cross-Sectional Studies; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Palliative Care; Retrospective Studies; Survival Analysis; Survival Rate; Transplantation, Homologous; Treatment Outcome

2018
Treatment of Philadelphia-negative myeloproliferative neoplasms in accelerated/blastic phase with azacytidine. Clinical results and identification of prognostic factors.
    Hematological oncology, 2019, Volume: 37, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Male; Melphalan; Middle Aged; Mutation; Myeloproliferative Disorders; Pipobroman; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Remission Induction; Retrospective Studies; Thrombocythemia, Essential; Treatment Outcome

2019
Clinical efficacy of second generation tyrosine kinase inhibitor and 5-azacytidine combination in chronic myelogenous leukaemia in myeloid blast crisis.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:17

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Dasatinib; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Thiazoles; Treatment Outcome

2013
Combination therapy with ruxolitinib plus 5-azacytidine or continuous infusion of low dose cytarabine is feasible in patients with blast-phase myeloproliferative neoplasms.
    British journal of haematology, 2014, Volume: 167, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Female; Hematologic Neoplasms; Humans; Male; Myeloproliferative Disorders; Nitriles; Pyrazoles; Pyrimidines

2014
Azacytidine for the treatment of retrospective analysis from the Gruppo Laziale for the study of Ph-negative MPN.
    Leukemia research, 2015, Volume: 39, Issue:8

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Disease Progression; Female; Humans; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Male; Middle Aged; Neoadjuvant Therapy; Retrospective Studies; Treatment Outcome

2015
Azacitidine treatment for patients with myelodysplastic syndrome and acute myeloid leukemia with chromosome 3q abnormalities.
    American journal of hematology, 2015, Volume: 90, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Allografts; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Chromosome Aberrations; Chromosomes, Human, Pair 3; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Retrospective Studies; Stem Cell Transplantation; Survival Rate

2015
Therapeutic benefit of decitabine, a hypomethylating agent, in patients with high-risk primary myelofibrosis and myeloproliferative neoplasm in accelerated or blastic/acute myeloid leukemia phase.
    Leukemia research, 2015, Volume: 39, Issue:9

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Decitabine; Female; Humans; Leukemia, Myeloid, Accelerated Phase; Male; Middle Aged; Primary Myelofibrosis; Prospective Studies; Remission Induction; Survival Analysis; Treatment Outcome

2015
Azacitidine in AML: a treatment option?
    Blood, 2015, Jul-16, Volume: 126, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Female; Humans; Leukemia, Myeloid, Acute; Male

2015
Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia.
    Leukemia research, 2016, Volume: 50

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Case-Control Studies; Cells, Cultured; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Exons; Female; Gene Expression Regulation, Leukemic; Gene Silencing; Genes, Tumor Suppressor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Receptors, Steroid; Receptors, Thyroid Hormone

2016
Caution using hypomethylating agents in myelodysplasia or myeloid leukemia with complex cytogenetics.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Aug-01, Volume: 28, Issue:22

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Chromosome Deletion; Female; Humans; Leukemia, Myeloid; Middle Aged; Myelodysplastic Syndromes

2010
Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia.
    Cancer, 2003, Aug-01, Volume: 98, Issue:3

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Decitabine; DNA Modification Methylases; Drug Administration Schedule; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged

2003
Downregulation of circadian clock genes in chronic myeloid leukemia: alternative methylation pattern of hPER3.
    Cancer science, 2006, Volume: 97, Issue:12

    Topics: Adult; ARNTL Transcription Factors; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Blast Crisis; Cell Cycle Proteins; Circadian Rhythm; CLOCK Proteins; Cryptochromes; DNA Methylation; Down-Regulation; Flavoproteins; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mutation; Nuclear Proteins; Period Circadian Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Trans-Activators; Transcription Factors

2006
Cytotoxic activity and mechanism of action of 5-Aza-2'-deoxycytidine in human CML cells.
    Leukemia research, 1993, Volume: 17, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Blast Crisis; Cytarabine; Decitabine; DNA, Neoplasm; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Time Factors; Tumor Cells, Cultured

1993
Chronic myelogenous leukemia in nonlymphoid blastic phase: analysis of the results of first salvage therapy with three different treatment approaches for 162 patients.
    Cancer, 1999, Dec-15, Volume: 86, Issue:12

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Blast Crisis; Decitabine; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Remission Induction; Salvage Therapy; Survival Analysis

1999
A comparison of the lethal effects in culture of cytosine arabinoside and arabinofuranosyl-5-azacytosine acting on the blast cells fo acute myeloblastic leukemia.
    Hematologic pathology, 1992, Volume: 6, Issue:3

    Topics: Acute Disease; Antineoplastic Agents; Azacitidine; Blast Crisis; Cell Survival; Cytarabine; Humans; Leukemia, Myeloid; Tumor Cells, Cultured

1992