azacitidine and Bladder Cancer

azacitidine has been researched along with Bladder Cancer in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (5.66)18.2507
2000's26 (49.06)29.6817
2010's21 (39.62)24.3611
2020's3 (5.66)2.80

Authors

AuthorsStudies
Babasaki, T; Harada, K; Hayashi, T; Maruyama, R; Murai, J; Pham, QT; Pommier, Y; Sakamoto, N; Sekino, Y; Sentani, K; Takashima, T; Takeda, M; Taniyama, D; Ukai, S; Yasui, W1
Ci, W; Fan, J; Guan, B; Guo, B; Li, J; Li, X; Liang, Y; Shi, Y; Tan, Y; Wang, P; Wu, Y; Xu, C; Yuan, C; Zhang, J; Zhang, Q; Zhou, L1
Henrique, R; Jerónimo, C; Nunes, SP; Paramio, JM1
Ambati, CR; Berg, S; Bhowmik, SK; Coarfa, C; Degener, S; Donepudi, SR; El-Zein, R; Gödde, D; Gu, F; Jin, F; Kaipparettu, BA; Karanam, B; Kavuri, SM; Kheradmand, F; Krishnapuram, R; Lerner, SP; Lotan, Y; Maity, S; Michailidis, G; Noldus, J; Piyarathna, DWB; Purwaha, P; Putluri, N; Putluri, V; Rajapakshe, K; Roghmann, F; Roth, S; Sreekumar, A; Störkel, S; Terris, MK; Thaiparambil, J; Vantaku, V; von Rundstedt, FC1
Attwood, K; Chatta, G; Granger, V; Gueron, G; Guru, K; Hu, Q; Johnson, C; Krishnan, N; McNally, L; Morrison, C; Pili, R; Rak, M; Ramakrishnan, S; Smit, E; Wang, D; Wang, J; Woloszynska-Read, A1
Anand, V; Appunni, S; Khandelwal, M; Mathur, S; Seth, A; Sharma, A; Singh, P1
Cao, Y; Chen, M; Li, Z; Qi, F; Qi, L; Zhang, H; Zu, X1
Liu, Q; Luo, C; Tao, J; Wang, Q; Wu, X; Xu, X; Zhang, Y1
Chan, MW; Chen, CJ; Lee, TC; Pu, YS; Wang, HH; Wu, MM1
Alp, E; Gurocak, S; Konac, E; Menevse, S; Onen, IH; Sozen, S; Varol, N; Yilmaz, A1
Bivalacqua, T; Brait, M; Driscoll, T; Hoque, MO; Maldonado, L; Michailidi, C; Munari, E; Netto, GJ; Schoenberg, M; Schultz, L; Sidransky, D1
Chan, HL; Chen, YY; Chuang, JJ; Dai, YC; Lin, WH; Lin, YL; Liu, YW1
Choi, YW; Devanand, P; Kim, SI; Kim, SJ; Kim, WJ; Lim, IK; Ryu, MS; Sheen, SS; Yim, H1
Kang, HW; Kim, JS; Kim, WJ; Kim, WT; Kim, YJ; Kim, YW; Lee, SC; Ryu, KH; Yoon, HY; Yun, SJ1
Chen, E; Luo, C; Quan, Z; Wang, X; Wang, Y; Wu, X; Yang, X1
Ding, XL; Liang, G; Wang, K; Yang, X1
Clozel, T; Elemento, O; Erdem, Z; Hassler, MR; Krzywinski, M; Robinson, BD; Shariat, SF; Xylinas, E; Zhuang, D1
Ito, N; Kamoto, T; Liu, Y; Matsui, Y; Nishiyama, H; Ogawa, O; Shang, D1
Li, Z; Yang, N1
Chihara, Y; Chuang, JC; Egger, G; Friedman, JM; Liang, G; Saito, Y1
Dai, X; Liu, X; Wu, B1
Chiyomaru, T; Enokida, H; Kagara, I; Kawahara, K; Kawakami, K; Mori, K; Nakagawa, M; Nishiyama, K; Seki, N; Tatarano, S1
Forni, G; Malentacchi, F; Orlando, C; Vinci, S1
Li, HL; Liu, CX; Xu, K; Xu, NR; Xu, YW; Zheng, SB1
Ai, X; Ju, ZH; Shi, TP; Wang, BJ; Wang, C; Ying, MG; Zhang, GX; Zhang, X1
Chiyomaru, T; Enokida, H; Kawahara, K; Kawakami, K; Matsuda, R; Matsumoto, M; Nakagawa, M; Nishiyama, K; Seki, N; Toki, K1
Luo, C; Pan, C; Pu, J; Shen, S; Wang, C; Wu, X; Yang, S1
Blizard, S; Catto, JW; Choudhry, HM; Dudziec, E; Glover, M; Hamdy, FC; Miah, S; Owen, HC1
Costa, VL; Danielsen, SA; Eknaes, M; Henrique, R; Jerónimo, C; Lind, GE; Lothe, RA; Morais, A; Oliveira, J; Patrício, P; Teixeira, MR1
Gordian, E; Ramachandran, K; Singal, R1
Dhawan, D; Hahn, NM; Knapp, DW; Olbricht, GR; Ramos-Vara, JA; Stewart, JC; Waddell, J; Zheng, R1
Gonzales, FA; Jones, PA; Liang, G; Lin, JC; Nguyen, CT; Velicescu, M; Weisenberger, DJ1
Cheng, JC; Gonzales, FA; Hu, YG; Jones, PA; Liang, G; Marquez, VE; Weisenberger, DJ; Xu, GL1
Hoshikawa, Y; Jonat, W; Jünemann, KP; Maass, N; Minei, S; Nagasaki, K; Sato, K; Sugimoto, S; Takimoto, Y; Zhang, M1
Grimm, MO; Jackson, P; Loberg, R; Marreiros, A; Nixdorf, S; Pienta, KJ; Russell, PJ1
Carroll, PR; Dahiya, R; Deguchi, M; Enokida, H; Igawa, M; Ishii, N; Kane, CJ; Kawakami, T; Miura, K; Nakajima, K; Ogishima, T; Shiina, H; Tokizane, T; Urakami, S1
Adachi, H; Dahiya, R; Enokida, H; Igawa, M; Kawakami, T; Kikuno, N; Kishi, H; Konety, BR; Li, LC; Ogishima, T; Ribeiro-Filho, LA; Shigeno, K; Shiina, H; Tanaka, Y; Terashima, M; Tokizane, T; Urakami, S; Yoneda, T1
Arens, N; Goerdt, S; Gratchev, A; Grobholz, R; Kannookadan, S; Kzhyshkowska, J; Muller-Molinet, I; Oerther, S; Utikal, J1
Christoph, F; Kempkensteffen, C; Köllermann, J; Krause, H; Miller, K; Schostak, M; Schrader, M; Weikert, S1
Antich, P; Benaim, EA; Fan, J; Frenkel, E; Hsieh, JT; Karam, JA; Mason, RP; Richer, E; Sagalowsky, AI; Stanfield, J1
Bergeron, A; Fradet, Y; Larue, H; Picard, V1
Chang, X; Ethier, SP; Guo, Z; Kim, MS; Kivirikko, KI; Liu, J; Maki, JM; Nagpal, JK; Sidransky, D; Trink, B; Wu, G1
Egger, G; Jeong, S; Jones, PA; Liang, G; Phiasivongsa, P; Redkar, S; Tang, C; Yoo, CB1
Eblin, KE; Futscher, BW; Gandolfi, AJ; Jensen, TJ; Novak, P1
Bender, CM; Jones, PA; Pao, MM1
Bender, CM; Gonzales, FA; Gonzalgo, ML; Hayashida, T; Jones, PA; Nguyen, HD; Nguyen, TT; Pao, MM; Tsai, YC1
Elder, PA; Habuchi, T; Knowles, MA; Luscombe, M1
Bender, CM; Gonzales, FA; Jones, PA; Liang, G; Markl, ID; Salem, CE1
Chang, SG; Chi, SG; Kim, JI; Lee, CH; Lee, SJ; Park, BJ; Park, JH1
Clark, S; Jackson, P; Kingsley, E; Millar, D; Ow, K; Russell, PJ; Yardley, G1
Fischer, J; Florl, AR; Maas, S; Müller, W; Pulte, T; Santourlidis, S; Schulz, WA; Warskulat, U1
Gonzales, FA; Jones, PA; Liang, G; Orntoft, TF; Thykjaer, T1
Gonzales, FA; Jones, PA; Nguyen, CT; Tsai, YC; Velicescu, M; Weisenberger, DJ1

Reviews

1 review(s) available for azacitidine and Bladder Cancer

ArticleYear
DNA Methylation as a Therapeutic Target for Bladder Cancer.
    Cells, 2020, 08-07, Volume: 9, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Humans; Urinary Bladder Neoplasms

2020

Other Studies

52 other study(ies) available for azacitidine and Bladder Cancer

ArticleYear
Prognostic impact of Schlafen 11 in bladder cancer patients treated with platinum-based chemotherapy.
    Cancer science, 2022, Volume: 113, Issue:2

    Topics: Aged; Antineoplastic Agents; Azacitidine; Benzamides; Biomarkers, Tumor; Cell Line, Tumor; Chemotherapy, Adjuvant; Cisplatin; Drug Resistance, Neoplasm; Drug Synergism; Female; GATA3 Transcription Factor; Humans; Male; Nuclear Proteins; Platinum; Prognosis; Pyridines; Urinary Bladder Neoplasms

2022
DNA methylation subtypes guiding prognostic assessment and linking to responses the DNA methyltransferase inhibitor SGI-110 in urothelial carcinoma.
    BMC medicine, 2022, 07-18, Volume: 20, Issue:1

    Topics: Azacitidine; Carcinoma, Transitional Cell; DNA Methylation; DNA Modification Methylases; Humans; Prognosis; Urinary Bladder Neoplasms

2022
Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer.
    Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:10

    Topics: Azacitidine; Benzo(a)pyrene; Biomarkers, Tumor; Butanones; Carcinogens; Cell Line, Tumor; Cohort Studies; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Adducts; DNA Damage; DNA Methylation; Early Detection of Cancer; Female; Humans; Male; Metabolome; Metabolomics; Mutagens; Neoplasm Grading; Nicotiana; Nitrosamines; Polycyclic Aromatic Hydrocarbons; Risk Assessment; Smoking; Tobacco Products; Urinary Bladder Neoplasms

2017
Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer.
    Cell death & disease, 2017, 12-14, Volume: 8, Issue:12

    Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Azacitidine; beta-Galactosidase; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Keratin-5; Muscle, Smooth; Neoplasm Invasiveness; Receptor, Notch1; Signal Transduction; Treatment Outcome; Urinary Bladder Neoplasms

2017
Decitabine augments cytotoxicity of cisplatin and doxorubicin to bladder cancer cells by activating hippo pathway through RASSF1A.
    Molecular and cellular biochemistry, 2018, Volume: 446, Issue:1-2

    Topics: Azacitidine; Cisplatin; Cytotoxins; Decitabine; Doxorubicin; HeLa Cells; Hippo Signaling Pathway; Humans; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Suppressor Proteins; Urinary Bladder Neoplasms

2018
5-Aza-2'-deoxycytidine enhances maspin expression and inhibits proliferation, migration, and invasion of the bladder cancer T24 cell line.
    Cancer biotherapy & radiopharmaceuticals, 2013, Volume: 28, Issue:4

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; Humans; RNA, Messenger; Serpins; Urinary Bladder Neoplasms

2013
Identification of hypermethylation in hepatocyte cell adhesion molecule gene promoter region in bladder carcinoma.
    International journal of medical sciences, 2013, Volume: 10, Issue:13

    Topics: Azacitidine; Base Sequence; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Primers; Flow Cytometry; Fluorescent Antibody Technique; Humans; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Urinary Bladder Neoplasms

2013
Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation.
    Archives of toxicology, 2014, Volume: 88, Issue:8

    Topics: Acute-Phase Proteins; Arsenites; Azacitidine; Cell Culture Techniques; Cell Line; Cell Proliferation; Chromatin Immunoprecipitation; Culture Media, Serum-Free; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Environmental Pollutants; Gene Silencing; Genome-Wide Association Study; Humans; Lipocalin-2; Lipocalins; Mutagenesis, Site-Directed; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Sodium Compounds; Time Factors; Urinary Bladder Neoplasms; Urothelium

2014
The epigenetically regulated effects of Wnt antagonists on the expression of genes in the apoptosis pathway in human bladder cancer cell line (T24).
    DNA and cell biology, 2014, Volume: 33, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D; Cytidine Triphosphate; Dose-Response Relationship, Drug; Epigenomics; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Hydroxamic Acids; Urinary Bladder Neoplasms; Wnt Proteins

2014
An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine.
    Oncotarget, 2014, Jul-30, Volume: 5, Issue:14

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Case-Control Studies; Cyclin A1; Cyclin D2; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Hydroxamic Acids; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Predictive Value of Tests; Promoter Regions, Genetic; Urinary Bladder Neoplasms

2014
Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.
    Toxicology and applied pharmacology, 2014, Sep-15, Volume: 279, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cell Line, Tumor; Coloring Agents; Decitabine; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Female; Glutathione Transferase; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mucous Membrane; Real-Time Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Urinary Bladder; Urinary Bladder Neoplasms

2014
Inhibition of bladder cancer invasion by Sp1-mediated BTG2 expression via inhibition of DNA methyltransferase 1.
    The FEBS journal, 2014, Volume: 281, Issue:24

    Topics: Azacitidine; Chromatin Assembly and Disassembly; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; Immediate-Early Proteins; Introns; Neoplasm Invasiveness; Promoter Regions, Genetic; Sp1 Transcription Factor; Tumor Suppressor Proteins; Up-Regulation; Urinary Bladder Neoplasms

2014
RSPH9 methylation pattern as a prognostic indicator in patients with non-muscle invasive bladder cancer.
    Oncology reports, 2016, Volume: 35, Issue:2

    Topics: Adult; Aged; Azacitidine; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cell Line, Tumor; Cytoskeletal Proteins; Disease-Free Survival; DNA Methylation; DNA, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Proportional Hazards Models; Urinary Bladder Neoplasms

2016
5-azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene.
    Oncology reports, 2016, Volume: 35, Issue:3

    Topics: Animals; Azacitidine; Carcinoma, Transitional Cell; Cell Cycle Proteins; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression Regulation, Neoplastic; Humans; Mice; Promoter Regions, Genetic; Proteins; RNA, Messenger; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2016
Isoform switching and exon skipping induced by the DNA methylation inhibitor 5-Aza-2'-deoxycytidine.
    Scientific reports, 2016, Apr-19, Volume: 6

    Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Exons; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Protein Isoforms; Sequence Analysis, RNA; Urinary Bladder Neoplasms

2016
An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer.
    Biomolecules, 2016, 09-02, Volume: 6, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cisplatin; Decitabine; Doxorubicin; Drug Resistance, Neoplasm; Epigenomics; Etoposide; Homeodomain Proteins; Humans; Hydroxamic Acids; Methylation; Neoadjuvant Therapy; Promoter Regions, Genetic; Urinary Bladder Neoplasms; Vinblastine; Vorinostat

2016
Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of bladder transitional cell carcinoma to Cisplatin.
    Urology, 2008, Volume: 71, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Carcinoma, Transitional Cell; Cell Line, Tumor; Cisplatin; Decitabine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Urinary Bladder Neoplasms

2008
[5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells].
    Zhonghua yi xue za zhi, 2008, Aug-19, Volume: 88, Issue:32

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Survival; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Histones; Humans; Lysine; Methylation; Promoter Regions, Genetic; Time Factors; Urinary Bladder Neoplasms

2008
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.
    Biochemical and biophysical research communications, 2009, Feb-13, Volume: 379, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Calcium-Binding Proteins; Cell Line, Tumor; Decitabine; EGF Family of Proteins; Endothelial Growth Factors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Male; MicroRNAs; Neoplasms; Phenylbutyrates; Promoter Regions, Genetic; Prostatic Neoplasms; Up-Regulation; Urinary Bladder Neoplasms

2009
Study of 5-Aza-CdR on transcription regulation of RASSF1A gene in the BIU87 cell line.
    Urologia internationalis, 2009, Volume: 82, Issue:1

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Suppressor Proteins; Urinary Bladder Neoplasms

2009
CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer.
    International journal of oncology, 2009, Volume: 34, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Cell Adhesion; Cell Movement; Cell Proliferation; Collagen; Collagen Type I; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoenzyme Techniques; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms

2009
Quantitative evaluation of DNA methylation by optimization of a differential-high resolution melt analysis protocol.
    Nucleic acids research, 2009, Volume: 37, Issue:12

    Topics: Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Genes, bcl-2; Humans; Nucleic Acid Denaturation; Polymerase Chain Reaction; Telomerase; Urinary Bladder Neoplasms

2009
[Reversion transcriptional expression of DAPK in bladder cancer T24 cells 5-aza-2'-deoxycytidine].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:9

    Topics: Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Death-Associated Protein Kinases; Decitabine; DNA Methylation; DNA Modification Methylases; Humans; Promoter Regions, Genetic; RNA, Messenger; Transcriptional Activation; Urinary Bladder Neoplasms

2009
[Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and apoptosis of ALDH1a2 gene in human bladder cancer cell lines].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2010, Mar-01, Volume: 48, Issue:5

    Topics: Aldehyde Dehydrogenase 1 Family; Apoptosis; Azacitidine; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Retinal Dehydrogenase; Urinary Bladder Neoplasms

2010
CpG hypermethylation of human four-and-a-half LIM domains 1 contributes to migration and invasion activity of human bladder cancer.
    International journal of molecular medicine, 2010, Volume: 26, Issue:2

    Topics: Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; DNA Methylation; Enzyme Inhibitors; Female; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Male; Middle Aged; Muscle Proteins; Neoplasm Invasiveness; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2010
Exon 2 methylation inhibits hepaCAM expression in transitional cell carcinoma of the bladder.
    Urologia internationalis, 2010, Volume: 85, Issue:3

    Topics: Aged; Azacitidine; Carcinoma, Transitional Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Epigenesis, Genetic; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Urinary Bladder Neoplasms

2010
Hypermethylation of CpG islands and shores around specific microRNAs and mirtrons is associated with the phenotype and presence of bladder cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Mar-15, Volume: 17, Issue:6

    Topics: Azacitidine; Cohort Studies; CpG Islands; DNA Methylation; Epigenesis, Genetic; Exons; Gene Silencing; Humans; Odds Ratio; Oligonucleotide Array Sequence Analysis; Phenotype; Prognosis; Urinary Bladder Neoplasms; Urothelium

2011
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers.
    Epigenetics, 2011, Sep-01, Volume: 6, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Cadherins; Carcinoma, Renal Cell; Case-Control Studies; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Male; Middle Aged; Promoter Regions, Genetic; Prostatic Neoplasms; ROC Curve; Sensitivity and Specificity; Urinary Bladder Neoplasms

2011
5-azacytidine reverses drug resistance in bladder cancer cells.
    Anticancer research, 2011, Volume: 31, Issue:11

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Blotting, Western; CARD Signaling Adaptor Proteins; Cell Cycle; Cell Cycle Proteins; Cisplatin; Cytoskeletal Proteins; DNA Methylation; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Real-Time Polymerase Chain Reaction; RNA, Messenger; Taxoids; Tumor Cells, Cultured; Tumor Suppressor Proteins; Urinary Bladder Neoplasms

2011
DNMT1: an emerging target in the treatment of invasive urinary bladder cancer.
    Urologic oncology, 2013, Volume: 31, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Dogs; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Immunohistochemistry; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Transcriptome; Urinary Bladder Neoplasms

2013
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.
    Cancer research, 2002, Nov-15, Volume: 62, Issue:22

    Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Culture Techniques; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Gene Silencing; Histones; Humans; Lysine; Methylation; Precipitin Tests; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF; Urinary Bladder Neoplasms

2002
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells.
    Molecular and cellular biology, 2004, Volume: 24, Issue:3

    Topics: Azacitidine; Cytidine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Genes, p16; Humans; Pyrimidine Nucleosides; Urinary Bladder Neoplasms

2004
Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
    Cancer letters, 2004, Jan-20, Volume: 203, Issue:2

    Topics: Adult; Aged; Azacitidine; Carcinoma, Transitional Cell; Cell Line, Tumor; Cytoplasm; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Luciferases; Male; Middle Aged; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Serpins; Transcriptional Activation; Urinary Bladder Neoplasms

2004
Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines.
    Cancer letters, 2004, Nov-25, Volume: 215, Issue:2

    Topics: Azacitidine; Clone Cells; Decitabine; DNA Methylation; Down-Regulation; Genes, Tumor Suppressor; Humans; Microfilament Proteins; Neoplasm Invasiveness; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms

2004
Inactivation of the hMSH3 mismatch repair gene in bladder cancer.
    Biochemical and biophysical research communications, 2004, Dec-17, Volume: 325, Issue:3

    Topics: Azacitidine; Base Pair Mismatch; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA Repair Enzymes; DNA-Binding Proteins; Female; Humans; Male; MutS Homolog 3 Protein; Urinary Bladder Neoplasms

2004
Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jan-15, Volume: 12, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; beta Catenin; Carcinoma, Transitional Cell; Carrier Proteins; Cell Line, Tumor; Cyclin D1; Decitabine; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Molecular Sequence Data; Proto-Oncogene Proteins c-myc; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Urinary Bladder Neoplasms; Wnt Proteins

2006
The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation.
    International journal of cancer, 2006, Nov-15, Volume: 119, Issue:10

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cloning, Molecular; Cosmids; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Microfilament Proteins; Neoplasm Proteins; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Trans-Activators; Transfection; Up-Regulation; Urinary Bladder Neoplasms

2006
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
    British journal of cancer, 2006, Dec-18, Volume: 95, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cells, Cultured; Cytidine; Death-Associated Protein Kinases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Kidney; Kidney Neoplasms; Male; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms

2006
The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy.
    International journal of cancer, 2007, Apr-15, Volume: 120, Issue:8

    Topics: Animals; Azacitidine; Blotting, Western; Carcinoma, Transitional Cell; Cell Cycle; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Depsipeptides; DNA Methylation; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Histones; Humans; Mice; Mice, Nude; Promoter Regions, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2007
MAGE-A9 mRNA and protein expression in bladder cancer.
    International journal of cancer, 2007, May-15, Volume: 120, Issue:10

    Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Azacitidine; Benzamides; Cell Line, Tumor; Decitabine; Gene Expression; Histone Deacetylase Inhibitors; Humans; Immunohistochemistry; Male; Neoplasm Proteins; Phenylbutyrates; Protein Isoforms; Pyridines; RNA, Messenger; Testicular Neoplasms; Urinary Bladder Neoplasms

2007
LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.
    Cancer research, 2007, May-01, Volume: 67, Issue:9

    Topics: Amino Acid Oxidoreductases; Azacitidine; Cell Line, Tumor; Cytoplasm; Decitabine; DNA Methylation; Epigenesis, Genetic; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; MAP Kinase Signaling System; Mutation; Neoplastic Stem Cells; Protein-Lysine 6-Oxidase; ras Proteins; Urinary Bladder Neoplasms

2007
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.
    Cancer research, 2007, Jul-01, Volume: 67, Issue:13

    Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Delivery Systems; Epigenesis, Genetic; Genetic Therapy; Humans; Models, Chemical; Myelodysplastic Syndromes; Oligonucleotides; Triazines; Urinary Bladder Neoplasms

2007
Epigenetic remodeling during arsenical-induced malignant transformation.
    Carcinogenesis, 2008, Volume: 29, Issue:8

    Topics: Acetylation; Arsenicals; Azacitidine; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Decitabine; Environmental Exposure; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Teratogens; Urinary Bladder Neoplasms; Urothelium

2008
Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines.
    Cancer research, 1998, Jan-01, Volume: 58, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Division; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; G1 Phase; Gene Expression; Humans; Mice; Mice, Nude; Neoplasms; Rats; Rats, Nude; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1998
The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines.
    Cancer research, 1998, Mar-15, Volume: 58, Issue:6

    Topics: Azacitidine; Carrier Proteins; Cell Cycle Proteins; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p19; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Promoter Regions, Genetic; Transcription, Genetic; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1998
Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33.
    Genomics, 1998, Mar-15, Volume: 48, Issue:3

    Topics: Amino Acid Sequence; Azacitidine; Base Sequence; Blotting, Northern; Blotting, Southern; Carcinoma, Transitional Cell; Cell Cycle Proteins; Chromosomes, Artificial, Yeast; Chromosomes, Human, Pair 9; CpG Islands; Decitabine; DNA Methylation; DNA, Complementary; Exons; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Introns; Molecular Sequence Data; Nerve Tissue Proteins; Polymorphism, Single-Stranded Conformational; Proteins; RNA, Messenger; Sequence Analysis, DNA; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; Urothelium

1998
PAX6 methylation and ectopic expression in human tumor cells.
    International journal of cancer, 2000, Jul-15, Volume: 87, Issue:2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Exons; Eye Proteins; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Paired Box Transcription Factors; PAX6 Transcription Factor; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2000
Frequent alteration of p63 expression in human primary bladder carcinomas.
    Cancer research, 2000, Jul-01, Volume: 60, Issue:13

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA-Binding Proteins; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, Tumor Suppressor; Humans; Membrane Proteins; Mutation; Phosphoproteins; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins; Urinary Bladder; Urinary Bladder Neoplasms

2000
Methylation of a CpG island within the promoter region of the KAI1 metastasis suppressor gene is not responsible for down-regulation of KAI1 expression in invasive cancers or cancer cell lines.
    Cancer letters, 2000, Sep-01, Volume: 157, Issue:2

    Topics: Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Transitional Cell; CpG Islands; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Kangai-1 Protein; Membrane Glycoproteins; Methylation; Molecular Sequence Data; Neoplasm Invasiveness; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2000
Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma.
    Molecular carcinogenesis, 2001, Volume: 32, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA Primers; DNA, Neoplasm; fas Receptor; Flow Cytometry; Gene Expression; Humans; Immunoenzyme Techniques; In Vitro Techniques; Male; Middle Aged; NF-kappa B; Oncogene Proteins v-rel; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiolester Hydrolases; Urinary Bladder Neoplasms

2001
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine.
    Cancer research, 2002, Feb-15, Volume: 62, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; CpG Islands; Decitabine; DNA Methylation; Fibroblasts; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Transcriptional Activation; Urinary Bladder Neoplasms

2002
Cell division is required for de novo methylation of CpG islands in bladder cancer cells.
    Cancer research, 2002, Apr-15, Volume: 62, Issue:8

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Cell Division; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Kinetics; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2002