azacitidine has been researched along with Bladder Cancer in 53 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (5.66) | 18.2507 |
2000's | 26 (49.06) | 29.6817 |
2010's | 21 (39.62) | 24.3611 |
2020's | 3 (5.66) | 2.80 |
Authors | Studies |
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Babasaki, T; Harada, K; Hayashi, T; Maruyama, R; Murai, J; Pham, QT; Pommier, Y; Sakamoto, N; Sekino, Y; Sentani, K; Takashima, T; Takeda, M; Taniyama, D; Ukai, S; Yasui, W | 1 |
Ci, W; Fan, J; Guan, B; Guo, B; Li, J; Li, X; Liang, Y; Shi, Y; Tan, Y; Wang, P; Wu, Y; Xu, C; Yuan, C; Zhang, J; Zhang, Q; Zhou, L | 1 |
Henrique, R; Jerónimo, C; Nunes, SP; Paramio, JM | 1 |
Ambati, CR; Berg, S; Bhowmik, SK; Coarfa, C; Degener, S; Donepudi, SR; El-Zein, R; Gödde, D; Gu, F; Jin, F; Kaipparettu, BA; Karanam, B; Kavuri, SM; Kheradmand, F; Krishnapuram, R; Lerner, SP; Lotan, Y; Maity, S; Michailidis, G; Noldus, J; Piyarathna, DWB; Purwaha, P; Putluri, N; Putluri, V; Rajapakshe, K; Roghmann, F; Roth, S; Sreekumar, A; Störkel, S; Terris, MK; Thaiparambil, J; Vantaku, V; von Rundstedt, FC | 1 |
Attwood, K; Chatta, G; Granger, V; Gueron, G; Guru, K; Hu, Q; Johnson, C; Krishnan, N; McNally, L; Morrison, C; Pili, R; Rak, M; Ramakrishnan, S; Smit, E; Wang, D; Wang, J; Woloszynska-Read, A | 1 |
Anand, V; Appunni, S; Khandelwal, M; Mathur, S; Seth, A; Sharma, A; Singh, P | 1 |
Cao, Y; Chen, M; Li, Z; Qi, F; Qi, L; Zhang, H; Zu, X | 1 |
Liu, Q; Luo, C; Tao, J; Wang, Q; Wu, X; Xu, X; Zhang, Y | 1 |
Chan, MW; Chen, CJ; Lee, TC; Pu, YS; Wang, HH; Wu, MM | 1 |
Alp, E; Gurocak, S; Konac, E; Menevse, S; Onen, IH; Sozen, S; Varol, N; Yilmaz, A | 1 |
Bivalacqua, T; Brait, M; Driscoll, T; Hoque, MO; Maldonado, L; Michailidi, C; Munari, E; Netto, GJ; Schoenberg, M; Schultz, L; Sidransky, D | 1 |
Chan, HL; Chen, YY; Chuang, JJ; Dai, YC; Lin, WH; Lin, YL; Liu, YW | 1 |
Choi, YW; Devanand, P; Kim, SI; Kim, SJ; Kim, WJ; Lim, IK; Ryu, MS; Sheen, SS; Yim, H | 1 |
Kang, HW; Kim, JS; Kim, WJ; Kim, WT; Kim, YJ; Kim, YW; Lee, SC; Ryu, KH; Yoon, HY; Yun, SJ | 1 |
Chen, E; Luo, C; Quan, Z; Wang, X; Wang, Y; Wu, X; Yang, X | 1 |
Ding, XL; Liang, G; Wang, K; Yang, X | 1 |
Clozel, T; Elemento, O; Erdem, Z; Hassler, MR; Krzywinski, M; Robinson, BD; Shariat, SF; Xylinas, E; Zhuang, D | 1 |
Ito, N; Kamoto, T; Liu, Y; Matsui, Y; Nishiyama, H; Ogawa, O; Shang, D | 1 |
Li, Z; Yang, N | 1 |
Chihara, Y; Chuang, JC; Egger, G; Friedman, JM; Liang, G; Saito, Y | 1 |
Dai, X; Liu, X; Wu, B | 1 |
Chiyomaru, T; Enokida, H; Kagara, I; Kawahara, K; Kawakami, K; Mori, K; Nakagawa, M; Nishiyama, K; Seki, N; Tatarano, S | 1 |
Forni, G; Malentacchi, F; Orlando, C; Vinci, S | 1 |
Li, HL; Liu, CX; Xu, K; Xu, NR; Xu, YW; Zheng, SB | 1 |
Ai, X; Ju, ZH; Shi, TP; Wang, BJ; Wang, C; Ying, MG; Zhang, GX; Zhang, X | 1 |
Chiyomaru, T; Enokida, H; Kawahara, K; Kawakami, K; Matsuda, R; Matsumoto, M; Nakagawa, M; Nishiyama, K; Seki, N; Toki, K | 1 |
Luo, C; Pan, C; Pu, J; Shen, S; Wang, C; Wu, X; Yang, S | 1 |
Blizard, S; Catto, JW; Choudhry, HM; Dudziec, E; Glover, M; Hamdy, FC; Miah, S; Owen, HC | 1 |
Costa, VL; Danielsen, SA; Eknaes, M; Henrique, R; Jerónimo, C; Lind, GE; Lothe, RA; Morais, A; Oliveira, J; Patrício, P; Teixeira, MR | 1 |
Gordian, E; Ramachandran, K; Singal, R | 1 |
Dhawan, D; Hahn, NM; Knapp, DW; Olbricht, GR; Ramos-Vara, JA; Stewart, JC; Waddell, J; Zheng, R | 1 |
Gonzales, FA; Jones, PA; Liang, G; Lin, JC; Nguyen, CT; Velicescu, M; Weisenberger, DJ | 1 |
Cheng, JC; Gonzales, FA; Hu, YG; Jones, PA; Liang, G; Marquez, VE; Weisenberger, DJ; Xu, GL | 1 |
Hoshikawa, Y; Jonat, W; Jünemann, KP; Maass, N; Minei, S; Nagasaki, K; Sato, K; Sugimoto, S; Takimoto, Y; Zhang, M | 1 |
Grimm, MO; Jackson, P; Loberg, R; Marreiros, A; Nixdorf, S; Pienta, KJ; Russell, PJ | 1 |
Carroll, PR; Dahiya, R; Deguchi, M; Enokida, H; Igawa, M; Ishii, N; Kane, CJ; Kawakami, T; Miura, K; Nakajima, K; Ogishima, T; Shiina, H; Tokizane, T; Urakami, S | 1 |
Adachi, H; Dahiya, R; Enokida, H; Igawa, M; Kawakami, T; Kikuno, N; Kishi, H; Konety, BR; Li, LC; Ogishima, T; Ribeiro-Filho, LA; Shigeno, K; Shiina, H; Tanaka, Y; Terashima, M; Tokizane, T; Urakami, S; Yoneda, T | 1 |
Arens, N; Goerdt, S; Gratchev, A; Grobholz, R; Kannookadan, S; Kzhyshkowska, J; Muller-Molinet, I; Oerther, S; Utikal, J | 1 |
Christoph, F; Kempkensteffen, C; Köllermann, J; Krause, H; Miller, K; Schostak, M; Schrader, M; Weikert, S | 1 |
Antich, P; Benaim, EA; Fan, J; Frenkel, E; Hsieh, JT; Karam, JA; Mason, RP; Richer, E; Sagalowsky, AI; Stanfield, J | 1 |
Bergeron, A; Fradet, Y; Larue, H; Picard, V | 1 |
Chang, X; Ethier, SP; Guo, Z; Kim, MS; Kivirikko, KI; Liu, J; Maki, JM; Nagpal, JK; Sidransky, D; Trink, B; Wu, G | 1 |
Egger, G; Jeong, S; Jones, PA; Liang, G; Phiasivongsa, P; Redkar, S; Tang, C; Yoo, CB | 1 |
Eblin, KE; Futscher, BW; Gandolfi, AJ; Jensen, TJ; Novak, P | 1 |
Bender, CM; Jones, PA; Pao, MM | 1 |
Bender, CM; Gonzales, FA; Gonzalgo, ML; Hayashida, T; Jones, PA; Nguyen, HD; Nguyen, TT; Pao, MM; Tsai, YC | 1 |
Elder, PA; Habuchi, T; Knowles, MA; Luscombe, M | 1 |
Bender, CM; Gonzales, FA; Jones, PA; Liang, G; Markl, ID; Salem, CE | 1 |
Chang, SG; Chi, SG; Kim, JI; Lee, CH; Lee, SJ; Park, BJ; Park, JH | 1 |
Clark, S; Jackson, P; Kingsley, E; Millar, D; Ow, K; Russell, PJ; Yardley, G | 1 |
Fischer, J; Florl, AR; Maas, S; Müller, W; Pulte, T; Santourlidis, S; Schulz, WA; Warskulat, U | 1 |
Gonzales, FA; Jones, PA; Liang, G; Orntoft, TF; Thykjaer, T | 1 |
Gonzales, FA; Jones, PA; Nguyen, CT; Tsai, YC; Velicescu, M; Weisenberger, DJ | 1 |
1 review(s) available for azacitidine and Bladder Cancer
Article | Year |
---|---|
DNA Methylation as a Therapeutic Target for Bladder Cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Humans; Urinary Bladder Neoplasms | 2020 |
52 other study(ies) available for azacitidine and Bladder Cancer
Article | Year |
---|---|
Prognostic impact of Schlafen 11 in bladder cancer patients treated with platinum-based chemotherapy.
Topics: Aged; Antineoplastic Agents; Azacitidine; Benzamides; Biomarkers, Tumor; Cell Line, Tumor; Chemotherapy, Adjuvant; Cisplatin; Drug Resistance, Neoplasm; Drug Synergism; Female; GATA3 Transcription Factor; Humans; Male; Nuclear Proteins; Platinum; Prognosis; Pyridines; Urinary Bladder Neoplasms | 2022 |
DNA methylation subtypes guiding prognostic assessment and linking to responses the DNA methyltransferase inhibitor SGI-110 in urothelial carcinoma.
Topics: Azacitidine; Carcinoma, Transitional Cell; DNA Methylation; DNA Modification Methylases; Humans; Prognosis; Urinary Bladder Neoplasms | 2022 |
Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer.
Topics: Azacitidine; Benzo(a)pyrene; Biomarkers, Tumor; Butanones; Carcinogens; Cell Line, Tumor; Cohort Studies; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Adducts; DNA Damage; DNA Methylation; Early Detection of Cancer; Female; Humans; Male; Metabolome; Metabolomics; Mutagens; Neoplasm Grading; Nicotiana; Nitrosamines; Polycyclic Aromatic Hydrocarbons; Risk Assessment; Smoking; Tobacco Products; Urinary Bladder Neoplasms | 2017 |
Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer.
Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Azacitidine; beta-Galactosidase; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Keratin-5; Muscle, Smooth; Neoplasm Invasiveness; Receptor, Notch1; Signal Transduction; Treatment Outcome; Urinary Bladder Neoplasms | 2017 |
Decitabine augments cytotoxicity of cisplatin and doxorubicin to bladder cancer cells by activating hippo pathway through RASSF1A.
Topics: Azacitidine; Cisplatin; Cytotoxins; Decitabine; Doxorubicin; HeLa Cells; Hippo Signaling Pathway; Humans; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2018 |
5-Aza-2'-deoxycytidine enhances maspin expression and inhibits proliferation, migration, and invasion of the bladder cancer T24 cell line.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; DNA Modification Methylases; Humans; RNA, Messenger; Serpins; Urinary Bladder Neoplasms | 2013 |
Identification of hypermethylation in hepatocyte cell adhesion molecule gene promoter region in bladder carcinoma.
Topics: Azacitidine; Base Sequence; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Primers; Flow Cytometry; Fluorescent Antibody Technique; Humans; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Urinary Bladder Neoplasms | 2013 |
Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation.
Topics: Acute-Phase Proteins; Arsenites; Azacitidine; Cell Culture Techniques; Cell Line; Cell Proliferation; Chromatin Immunoprecipitation; Culture Media, Serum-Free; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Environmental Pollutants; Gene Silencing; Genome-Wide Association Study; Humans; Lipocalin-2; Lipocalins; Mutagenesis, Site-Directed; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Sodium Compounds; Time Factors; Urinary Bladder Neoplasms; Urothelium | 2014 |
The epigenetically regulated effects of Wnt antagonists on the expression of genes in the apoptosis pathway in human bladder cancer cell line (T24).
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D; Cytidine Triphosphate; Dose-Response Relationship, Drug; Epigenomics; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Hydroxamic Acids; Urinary Bladder Neoplasms; Wnt Proteins | 2014 |
An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Case-Control Studies; Cyclin A1; Cyclin D2; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Hydroxamic Acids; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Predictive Value of Tests; Promoter Regions, Genetic; Urinary Bladder Neoplasms | 2014 |
Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cell Line, Tumor; Coloring Agents; Decitabine; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Female; Glutathione Transferase; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mucous Membrane; Real-Time Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Urinary Bladder; Urinary Bladder Neoplasms | 2014 |
Inhibition of bladder cancer invasion by Sp1-mediated BTG2 expression via inhibition of DNA methyltransferase 1.
Topics: Azacitidine; Chromatin Assembly and Disassembly; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; Immediate-Early Proteins; Introns; Neoplasm Invasiveness; Promoter Regions, Genetic; Sp1 Transcription Factor; Tumor Suppressor Proteins; Up-Regulation; Urinary Bladder Neoplasms | 2014 |
RSPH9 methylation pattern as a prognostic indicator in patients with non-muscle invasive bladder cancer.
Topics: Adult; Aged; Azacitidine; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cell Line, Tumor; Cytoskeletal Proteins; Disease-Free Survival; DNA Methylation; DNA, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Proteins; Prognosis; Proportional Hazards Models; Urinary Bladder Neoplasms | 2016 |
5-azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene.
Topics: Animals; Azacitidine; Carcinoma, Transitional Cell; Cell Cycle Proteins; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression Regulation, Neoplastic; Humans; Mice; Promoter Regions, Genetic; Proteins; RNA, Messenger; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2016 |
Isoform switching and exon skipping induced by the DNA methylation inhibitor 5-Aza-2'-deoxycytidine.
Topics: Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Exons; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Protein Isoforms; Sequence Analysis, RNA; Urinary Bladder Neoplasms | 2016 |
An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer.
Topics: Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Cisplatin; Decitabine; Doxorubicin; Drug Resistance, Neoplasm; Epigenomics; Etoposide; Homeodomain Proteins; Humans; Hydroxamic Acids; Methylation; Neoadjuvant Therapy; Promoter Regions, Genetic; Urinary Bladder Neoplasms; Vinblastine; Vorinostat | 2016 |
Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of bladder transitional cell carcinoma to Cisplatin.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Carcinoma, Transitional Cell; Cell Line, Tumor; Cisplatin; Decitabine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Urinary Bladder Neoplasms | 2008 |
[5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells].
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Survival; Core Binding Factor Alpha 3 Subunit; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Histones; Humans; Lysine; Methylation; Promoter Regions, Genetic; Time Factors; Urinary Bladder Neoplasms | 2008 |
Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.
Topics: Antineoplastic Agents; Azacitidine; Calcium-Binding Proteins; Cell Line, Tumor; Decitabine; EGF Family of Proteins; Endothelial Growth Factors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Male; MicroRNAs; Neoplasms; Phenylbutyrates; Promoter Regions, Genetic; Prostatic Neoplasms; Up-Regulation; Urinary Bladder Neoplasms | 2009 |
Study of 5-Aza-CdR on transcription regulation of RASSF1A gene in the BIU87 cell line.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2009 |
CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Biomarkers, Tumor; Cell Adhesion; Cell Movement; Cell Proliferation; Collagen; Collagen Type I; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoenzyme Techniques; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms | 2009 |
Quantitative evaluation of DNA methylation by optimization of a differential-high resolution melt analysis protocol.
Topics: Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Genes, bcl-2; Humans; Nucleic Acid Denaturation; Polymerase Chain Reaction; Telomerase; Urinary Bladder Neoplasms | 2009 |
[Reversion transcriptional expression of DAPK in bladder cancer T24 cells 5-aza-2'-deoxycytidine].
Topics: Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Death-Associated Protein Kinases; Decitabine; DNA Methylation; DNA Modification Methylases; Humans; Promoter Regions, Genetic; RNA, Messenger; Transcriptional Activation; Urinary Bladder Neoplasms | 2009 |
[Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and apoptosis of ALDH1a2 gene in human bladder cancer cell lines].
Topics: Aldehyde Dehydrogenase 1 Family; Apoptosis; Azacitidine; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Retinal Dehydrogenase; Urinary Bladder Neoplasms | 2010 |
CpG hypermethylation of human four-and-a-half LIM domains 1 contributes to migration and invasion activity of human bladder cancer.
Topics: Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; DNA Methylation; Enzyme Inhibitors; Female; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Male; Middle Aged; Muscle Proteins; Neoplasm Invasiveness; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2010 |
Exon 2 methylation inhibits hepaCAM expression in transitional cell carcinoma of the bladder.
Topics: Aged; Azacitidine; Carcinoma, Transitional Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Epigenesis, Genetic; Exons; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Urinary Bladder Neoplasms | 2010 |
Hypermethylation of CpG islands and shores around specific microRNAs and mirtrons is associated with the phenotype and presence of bladder cancer.
Topics: Azacitidine; Cohort Studies; CpG Islands; DNA Methylation; Epigenesis, Genetic; Exons; Gene Silencing; Humans; Odds Ratio; Oligonucleotide Array Sequence Analysis; Phenotype; Prognosis; Urinary Bladder Neoplasms; Urothelium | 2011 |
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Cadherins; Carcinoma, Renal Cell; Case-Control Studies; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Male; Middle Aged; Promoter Regions, Genetic; Prostatic Neoplasms; ROC Curve; Sensitivity and Specificity; Urinary Bladder Neoplasms | 2011 |
5-azacytidine reverses drug resistance in bladder cancer cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Blotting, Western; CARD Signaling Adaptor Proteins; Cell Cycle; Cell Cycle Proteins; Cisplatin; Cytoskeletal Proteins; DNA Methylation; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Real-Time Polymerase Chain Reaction; RNA, Messenger; Taxoids; Tumor Cells, Cultured; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2011 |
DNMT1: an emerging target in the treatment of invasive urinary bladder cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Dogs; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Immunohistochemistry; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Transcriptome; Urinary Bladder Neoplasms | 2013 |
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.
Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Culture Techniques; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Gene Silencing; Histones; Humans; Lysine; Methylation; Precipitin Tests; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF; Urinary Bladder Neoplasms | 2002 |
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells.
Topics: Azacitidine; Cytidine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Genes, p16; Humans; Pyrimidine Nucleosides; Urinary Bladder Neoplasms | 2004 |
Expression and regulation of tumor suppressor gene maspin in human bladder cancer.
Topics: Adult; Aged; Azacitidine; Carcinoma, Transitional Cell; Cell Line, Tumor; Cytoplasm; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Genes, Tumor Suppressor; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Luciferases; Male; Middle Aged; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Serpins; Transcriptional Activation; Urinary Bladder Neoplasms | 2004 |
Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines.
Topics: Azacitidine; Clone Cells; Decitabine; DNA Methylation; Down-Regulation; Genes, Tumor Suppressor; Humans; Microfilament Proteins; Neoplasm Invasiveness; Neoplasm Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms | 2004 |
Inactivation of the hMSH3 mismatch repair gene in bladder cancer.
Topics: Azacitidine; Base Pair Mismatch; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA Repair Enzymes; DNA-Binding Proteins; Female; Humans; Male; MutS Homolog 3 Protein; Urinary Bladder Neoplasms | 2004 |
Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; beta Catenin; Carcinoma, Transitional Cell; Carrier Proteins; Cell Line, Tumor; Cyclin D1; Decitabine; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; Molecular Sequence Data; Proto-Oncogene Proteins c-myc; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Urinary Bladder Neoplasms; Wnt Proteins | 2006 |
The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cloning, Molecular; Cosmids; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Microfilament Proteins; Neoplasm Proteins; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Trans-Activators; Transfection; Up-Regulation; Urinary Bladder Neoplasms | 2006 |
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cells, Cultured; Cytidine; Death-Associated Protein Kinases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Kidney; Kidney Neoplasms; Male; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms | 2006 |
The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy.
Topics: Animals; Azacitidine; Blotting, Western; Carcinoma, Transitional Cell; Cell Cycle; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Depsipeptides; DNA Methylation; Enzyme Inhibitors; Female; Histone Deacetylase Inhibitors; Histones; Humans; Mice; Mice, Nude; Promoter Regions, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2007 |
MAGE-A9 mRNA and protein expression in bladder cancer.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Azacitidine; Benzamides; Cell Line, Tumor; Decitabine; Gene Expression; Histone Deacetylase Inhibitors; Humans; Immunohistochemistry; Male; Neoplasm Proteins; Phenylbutyrates; Protein Isoforms; Pyridines; RNA, Messenger; Testicular Neoplasms; Urinary Bladder Neoplasms | 2007 |
LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.
Topics: Amino Acid Oxidoreductases; Azacitidine; Cell Line, Tumor; Cytoplasm; Decitabine; DNA Methylation; Epigenesis, Genetic; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; MAP Kinase Signaling System; Mutation; Neoplastic Stem Cells; Protein-Lysine 6-Oxidase; ras Proteins; Urinary Bladder Neoplasms | 2007 |
Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Delivery Systems; Epigenesis, Genetic; Genetic Therapy; Humans; Models, Chemical; Myelodysplastic Syndromes; Oligonucleotides; Triazines; Urinary Bladder Neoplasms | 2007 |
Epigenetic remodeling during arsenical-induced malignant transformation.
Topics: Acetylation; Arsenicals; Azacitidine; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Decitabine; Environmental Exposure; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Teratogens; Urinary Bladder Neoplasms; Urothelium | 2008 |
Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Division; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; G1 Phase; Gene Expression; Humans; Mice; Mice, Nude; Neoplasms; Rats; Rats, Nude; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1998 |
The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines.
Topics: Azacitidine; Carrier Proteins; Cell Cycle Proteins; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p19; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Promoter Regions, Genetic; Transcription, Genetic; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1998 |
Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33.
Topics: Amino Acid Sequence; Azacitidine; Base Sequence; Blotting, Northern; Blotting, Southern; Carcinoma, Transitional Cell; Cell Cycle Proteins; Chromosomes, Artificial, Yeast; Chromosomes, Human, Pair 9; CpG Islands; Decitabine; DNA Methylation; DNA, Complementary; Exons; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Introns; Molecular Sequence Data; Nerve Tissue Proteins; Polymorphism, Single-Stranded Conformational; Proteins; RNA, Messenger; Sequence Analysis, DNA; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; Urothelium | 1998 |
PAX6 methylation and ectopic expression in human tumor cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Exons; Eye Proteins; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Paired Box Transcription Factors; PAX6 Transcription Factor; Promoter Regions, Genetic; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2000 |
Frequent alteration of p63 expression in human primary bladder carcinomas.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA-Binding Proteins; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes, p53; Genes, Tumor Suppressor; Humans; Membrane Proteins; Mutation; Phosphoproteins; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins; Urinary Bladder; Urinary Bladder Neoplasms | 2000 |
Methylation of a CpG island within the promoter region of the KAI1 metastasis suppressor gene is not responsible for down-regulation of KAI1 expression in invasive cancers or cancer cell lines.
Topics: Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Transitional Cell; CpG Islands; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Kangai-1 Protein; Membrane Glycoproteins; Methylation; Molecular Sequence Data; Neoplasm Invasiveness; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2000 |
Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma.
Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA Primers; DNA, Neoplasm; fas Receptor; Flow Cytometry; Gene Expression; Humans; Immunoenzyme Techniques; In Vitro Techniques; Male; Middle Aged; NF-kappa B; Oncogene Proteins v-rel; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiolester Hydrolases; Urinary Bladder Neoplasms | 2001 |
Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; CpG Islands; Decitabine; DNA Methylation; Fibroblasts; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Transcriptional Activation; Urinary Bladder Neoplasms | 2002 |
Cell division is required for de novo methylation of CpG islands in bladder cancer cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Cell Division; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, p16; Humans; Kinetics; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 2002 |