Compounds > azacitidine

azacitidine and Astrocytoma, Grade IV

azacitidine has been researched along with Astrocytoma, Grade IV in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (7.69)18.2507
2000's12 (30.77)29.6817
2010's22 (56.41)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Jaal, J; Laasfeld, T; Lavogina, D; Lust, H; Vardja, M1
Kavoosi, F; Sanaei, M1
Fichtner, I; Hanisch, UK; Hoffmann, J; Joedicke, A; Kratzsch, T; Kuhn, SA; Vajkoczy, P1
Davoudi, B; Ekström, TJ; Estekizadeh, A; Hu, LF; Landázuri, N; Nawaz, I; Pantalone, MR; Rahbar, A; Stragliotto, G1
Bai, Y; Bao, ZS; Chen, Y; Wang, LJ; Yan, ZH; Zhang, QG; Zhang, W1
Dolan, ME; Godley, LA; Moen, EL; Stark, AL; Zhang, W1
Han, L; Jiang, K; Kang, C; Liu, X; Ning, X; Shi, Z; Zhang, A; Zhang, Q1
Cui, Y; Irudayaraj, J; Naz, A; Thompson, DH1
Chakrabarti, M; Ray, SK1
Antonios, JP; Everson, RG; Garrett, MC; Kruse, CA; Li, G; Li, N; Liau, LM; Lisiero, DN; Prins, RM; Scharnweber, R; Soto, H; Yong, WH1
Berdasco, M; Caba, O; Cabeza, L; Gónzalez, B; Melguizo, C; Ortiz, R; Perazzoli, G; Prados, J1
Guttin, A; Ipas, H; Issartel, JP1
Jha, P; Julka, PK; Kumar, A; Mallick, S; Pathak, P; Purkait, S; Sarkar, C; Sharma, BS; Sharma, MC; Sharma, V; Suri, A; Suri, V1
Ansari, M; Fallah, S; Ghasemi, A2
Admon, A; Barnea, E; Kadosh, DM; Shraibman, B1
Aoyanagi, E; Kimura, T; Kohsaka, S; Nishihara, H; Sasai, K; Tabu, K; Tanaka, S; Tanino, M; Wang, L1
Eling, TE; Kamitani, H; Watanabe, T; Yoshioka, H1
Ahuja, N; Baylin, SB; Costello, JF; Easwaran, H; Eberhart, CG; Glöckner, SC; Herman, JG; James, CD; Laterra, J; Lin, S; Ohm, JE; Riggins, G; Schuebel, KE; Tsai, HC; Vescovi, AL; Yi, JM1
Bian, X; Chen, K; Dunlop, NM; Gao, Y; Gong, W; Howard, OM; Huang, J; Wang, JM1
Chang, WS; Chen, PY; Lai, YK; Wu, CW1
Liao, X; Liu, W; Lu, N; Wong, CW; Xu, J1
Eling, TE; Kadowaki, M; Kamitani, H; Wade, PA; Watanabe, T; Yoshioka, H1
Hong, X; Kalkanis, SN; Lemke, N; Nelson, K1
Adamson, DC; Bigner, D; Bortoff, K; Di, C; Duncan, C; Fu, J; Gregory, S; Killela, P; Lin, N; McLendon, R; Truszkowski, P1
Chie, EK; Kim, HJ; Kim, IA; Kim, IH; Kim, JH; Young, PD1
Bogiel, T; Carro, MS; Claus, R; Dai, F; Döbrössy, M; Doostkam, S; Firat, E; Herold-Mende, C; Kahlert, UD; Maciaczyk, D; Maciaczyk, J; Niedermann, G; Nikkhah, G; Prinz, M1
Bernaudin, M; Carlotti, CG; Carosella, ED; Donadi, EA; Ferrone, S; Flajollet, S; Jensen, SS; Kristensen, BW; Lechapt-Zalcman, E; Moreau, P; Pancoto, JT; Poras, I; Simões, RT; Valable, S; Wastowski, IJ; Yaghi, L1
Awad, M; Bomalaski, J; Coley, HM; Crook, T; Hatzimichael, E; Janczar, K; Langer, J; Lattanzio, L; Lo Nigro, C; O'Neil, K; Roncaroli, F; Singh, P; Syed, N; Szlosarek, P1
D'Ambrosio, E; Di Nardo, P; Grassi, G; Grassi, M; Kaiser, H; Kandolf, R; Kuhn, A; Küpper, JH; Maccaroni, P; Meyer, R; Pascale, E1
Ali-Osman, F; Dinh, DH; Foster, DC; Gujrati, M; Kisiel, W; Kondraganti, S; Konduri, SD; Lakka, SS; Olivero, WC; Rao, JS; Srivenugopal, KS; Yanamandra, N1
Blaschke, B; Knobbe, CB; Reifenberger, G; Reifenberger, J1
Black, KL; Liu, G; Wheeler, CJ; Ying, H; Yu, JS; Zeng, G1
Bartucci, M; Crinò, L; De Maria, R; Eramo, A; Larocca, LM; Lotti, F; Pallini, R; Patti, M; Peschle, C; Ricci-Vitiani, L; Sette, G; Signore, M; Stassi, G1
Fields, CR; Kim, JH; Kim, TY; Robertson, KD; Zhong, S1
Ehrich, M; Louis, DN; Mueller, W; Nutt, CL; Riemenschneider, MJ; van den Boom, D; von Deimling, A1
Eyre, HJ; Selby, GB; Townsend, J; Upchurch, C1
Bourgeois, CA; Delattre, JY; Dutrillaux, AM; Dutrillaux, B; Kokalj-Vokac, N; Malfoy, B; Poisson, M; Vega, F1
Berger, MS; Cavenee, WK; Costello, JF; Huang, HS1

Trials

1 trial(s) available for azacitidine and Astrocytoma, Grade IV

ArticleYear
A phase II evaluation of fazarabine in high-grade gliomas: a Southwest Oncology Group study.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Astrocytoma; Azacitidine; Brain Neoplasms; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Southwestern United States; Treatment Failure

1994

Other Studies

38 other study(ies) available for azacitidine and Astrocytoma, Grade IV

ArticleYear
Viability fingerprint of glioblastoma cell lines: roles of mitotic, proliferative, and epigenetic targets.
    Scientific reports, 2021, 10-13, Volume: 11, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Lomustine; Temozolomide

2021
The Effect of 5-aza,2'-deoxyCytidine (5 AZA CdR or Decitabine) on Extrinsic, Intrinsic, and JAK/STAT Pathways in Neuroblastoma and Glioblastoma Cells Lines.
    Asian Pacific journal of cancer prevention : APJCP, 2023, Jun-01, Volume: 24, Issue:6

    Topics: Azacitidine; Cell Line; Cell Line, Tumor; Decitabine; Deoxycytidine; DNA Methylation; Glioblastoma; Humans; Janus Kinases; Neuroblastoma; Signal Transduction; STAT Transcription Factors

2023
Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas.
    Journal of cancer research and clinical oncology, 2018, Volume: 144, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Glioblastoma; Humans; Mice, Inbred NOD; Mice, Knockout; Mice, Nude; Mice, SCID; Tumor Burden; Xenograft Model Antitumor Assays

2018
5‑Azacytidine treatment results in nuclear exclusion of DNA methyltransferase‑1, as well as reduced proliferation and invasion in human cytomegalovirus‑infected glioblastoma cells.
    Oncology reports, 2019, Volume: 41, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cytomegalovirus; Cytoplasm; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Female; Glioblastoma; Humans; Male; Middle Aged; Treatment Outcome; Viral Envelope Proteins; Virus Replication

2019
Hypermethylation of testis derived transcript gene promoter significantly correlates with worse outcomes in glioblastoma patients.
    Chinese medical journal, 2013, Volume: 126, Issue:11

    Topics: Azacitidine; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cytoskeletal Proteins; Decitabine; DNA Methylation; Glioblastoma; Humans; LIM Domain Proteins; Promoter Regions, Genetic; RNA-Binding Proteins; Treatment Outcome

2013
The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Azacitidine; Cell Line, Tumor; CpG Islands; Cytosine; Dacarbazine; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Quantitative Trait Loci; Temozolomide; Tumor Suppressor Proteins

2014
DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression.
    Cancer letters, 2015, Apr-10, Volume: 359, Issue:2

    Topics: Adenosine; Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Decitabine; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Histones; Humans; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Polycomb Repressive Complex 2; Stomach Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2015
Decitabine nanoconjugate sensitizes human glioblastoma cells to temozolomide.
    Molecular pharmaceutics, 2015, Apr-06, Volume: 12, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Azacitidine; Biocompatible Materials; Boron Compounds; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Decitabine; DNA Methylation; Drug Delivery Systems; Drug Synergism; Glioblastoma; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Methacrylates; Methylmethacrylates; Micelles; Nanoconjugates; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence; Temozolomide

2015
Direct transfection of miR-137 mimics is more effective than DNA demethylation of miR-137 promoter to augment anti-tumor mechanisms of delphinidin in human glioblastoma U87MG and LN18 cells.
    Gene, 2015, Nov-15, Volume: 573, Issue:1

    Topics: Anthocyanins; Azacitidine; Brain Neoplasms; Cell Division; Cell Line, Tumor; DNA Methylation; Glioblastoma; Humans; MicroRNAs; Promoter Regions, Genetic; Transfection

2015
Efficacy of systemic adoptive transfer immunotherapy targeting NY-ESO-1 for glioblastoma.
    Neuro-oncology, 2016, Volume: 18, Issue:3

    Topics: Animals; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Decitabine; Disease Models, Animal; Glioblastoma; Humans; Immunotherapy, Adoptive; Mice; T-Lymphocytes

2016
Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: AC133 Antigen; Antigens, CD; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Cell Line, Tumor; Dacarbazine; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; Guanine; Humans; Inhibitory Concentration 50; Peptides; Promoter Regions, Genetic; Temozolomide; Tumor Suppressor Proteins

2015
Exosomal MicroRNAs in Tumoral U87 MG Versus Normal Astrocyte Cells.
    MicroRNA (Shariqah, United Arab Emirates), 2015, Volume: 4, Issue:2

    Topics: Aniline Compounds; Astrocytes; Azacitidine; Benzylidene Compounds; Biological Transport; Cell Line, Tumor; Decitabine; Exosomes; Gene Expression Profiling; Gene Expression Regulation; Glioblastoma; Humans; Hypoxia; MicroRNAs; Models, Biological; Phenotype

2015
Expression of DNA methyltransferases 1 and 3B correlates with EZH2 and this 3-marker epigenetic signature predicts outcome in glioblastomas.
    Experimental and molecular pathology, 2016, Volume: 100, Issue:2

    Topics: Azacitidine; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Multivariate Analysis; Outcome Assessment, Health Care; Polycomb Repressive Complex 2; Prognosis; Proportional Hazards Models; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference

2016
MiR-153 as a Tumor Suppressor in Glioblastoma Multiforme is Downregulated by DNA Methylation.
    Clinical laboratory, 2016, Volume: 62, Issue:4

    Topics: Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Genes, Tumor Suppressor; Glioblastoma; Humans; MicroRNAs; Promoter Regions, Genetic

2016
Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy.
    Molecular & cellular proteomics : MCP, 2016, Volume: 15, Issue:9

    Topics: Antigens, Neoplasm; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; HLA Antigens; Humans; Immunotherapy; Peptides; Proteomics; Sequence Analysis, RNA

2016
MicroRNA-149 is epigenetically silenced tumor-suppressive microRNA, involved in cell proliferation and downregulation of AKT1 and cyclin D1 in human glioblastoma multiforme.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2016, Volume: 94, Issue:6

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Base Sequence; Brain; Brain Neoplasms; Cell Proliferation; Cyclin D1; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; MicroRNAs; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured

2016
Promoter hypomethylation regulates CD133 expression in human gliomas.
    Cell research, 2008, Volume: 18, Issue:10

    Topics: 5' Untranslated Regions; AC133 Antigen; Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; Humans; Peptides; Promoter Regions, Genetic; Tumor Cells, Cultured

2008
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A.
    The Journal of biological chemistry, 2008, Nov-28, Volume: 283, Issue:48

    Topics: Azacitidine; Cell Line, Tumor; Decitabine; Early Growth Response Protein 1; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioblastoma; Growth Differentiation Factor 15; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Sp1 Transcription Factor; Up-Regulation

2008
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
    Cancer research, 2008, Oct-01, Volume: 68, Issue:19

    Topics: AC133 Antigen; Animals; Antigens, CD; Antineoplastic Agents; Azacitidine; Brain Neoplasms; Caco-2 Cells; Carcinoma; Colorectal Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Peptides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2008
Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation.
    Carcinogenesis, 2009, Volume: 30, Issue:2

    Topics: Animals; Azacitidine; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Chemotaxis; Decitabine; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Methylation; Mice; Mice, Nude; Neoplasm Transplantation; Promoter Regions, Genetic; Receptors, Formyl Peptide; Transplantation, Heterologous; Tumor Suppressor Protein p53

2009
c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair.
    Molecular and cellular neurosciences, 2009, Volume: 42, Issue:1

    Topics: Apoptosis Regulatory Proteins; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Glioblastoma; Humans; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuroblastoma; Neuropeptides; Neuroserpin; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serpins; Transcriptional Activation

2009
Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines.
    International journal of cancer, 2011, Nov-15, Volume: 129, Issue:10

    Topics: Azacitidine; Cell Line, Tumor; Chromatin; Decitabine; Glioblastoma; Humans; Insulin Receptor Substrate Proteins; MicroRNAs; Phenylbutyrates

2011
DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines.
    International journal of cancer, 2012, Jan-15, Volume: 130, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azacitidine; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Decitabine; DNA Methylation; Early Growth Response Protein 1; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Growth Differentiation Factor 15; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Sulindac; Transfection

2012
Heparanase expression is associated with histone modifications in glioblastoma.
    International journal of oncology, 2012, Volume: 40, Issue:2

    Topics: Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; Decitabine; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation, Neoplastic; Glioblastoma; Glucuronidase; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Molecular Sequence Data; NF-kappa B p50 Subunit; Promoter Regions, Genetic; Protein Processing, Post-Translational; Transcription Factor RelA

2012
Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma.
    Molecular cancer research : MCR, 2012, Volume: 10, Issue:2

    Topics: Azacitidine; Brain Neoplasms; Cell Adhesion Molecules; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; RNA, Small Interfering

2012
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.
    Radiation oncology (London, England), 2012, Mar-20, Volume: 7

    Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine

2012
Resistance to hypoxia-induced, BNIP3-mediated cell death contributes to an increase in a CD133-positive cell population in human glioblastomas in vitro.
    Journal of neuropathology and experimental neurology, 2012, Volume: 71, Issue:12

    Topics: AC133 Antigen; Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Brain Neoplasms; Cell Death; Cell Hypoxia; Cell Line; Cell Proliferation; Chromatin Immunoprecipitation; DNA Methylation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; Humans; Membrane Proteins; Peptides; Proto-Oncogene Proteins; Signal Transduction; Transfection

2012
Human leukocyte antigen-G is frequently expressed in glioblastoma and may be induced in vitro by combined 5-aza-2'-deoxycytidine and interferon-γ treatments: results from a multicentric study.
    The American journal of pathology, 2013, Volume: 182, Issue:2

    Topics: Acetylation; Aged; Antigen Presentation; Azacitidine; beta 2-Microglobulin; Biopsy; Brain Neoplasms; Cell Line, Tumor; Chromatin Assembly and Disassembly; Decitabine; DNA Methylation; Female; Glioblastoma; HLA-G Antigens; Humans; Interferon-gamma; Male; Middle Aged; Paraffin Embedding; Prognosis; Promoter Regions, Genetic; Survival Analysis; Transcription, Genetic; Up-Regulation

2013
Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma.
    Cell death & disease, 2013, Jan-17, Volume: 4

    Topics: Apoptosis; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Autophagy; Azacitidine; Central Nervous System Neoplasms; Chloroquine; CpG Islands; Decitabine; DNA Methylation; Epigenomics; Glioblastoma; Humans; Hydrolases; Polyethylene Glycols; RNA Interference; RNA, Small Interfering; Stilbenes; Tumor Cells, Cultured; Up-Regulation

2013
Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87.
    Carcinogenesis, 2003, Volume: 24, Issue:10

    Topics: Animals; Azacitidine; Cytomegalovirus; DNA Methylation; DNA Replication; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Models, Theoretical; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Time Factors; Transfection; Tumor Cells, Cultured

2003
Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
    Oncogene, 2003, Jul-17, Volume: 22, Issue:29

    Topics: Azacitidine; Brain Neoplasms; Chromatin; Chromosomal Proteins, Non-Histone; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme Inhibitors; Gene Silencing; Glioblastoma; Glioma; Glycoproteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Methyl-CpG-Binding Protein 2; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins

2003
Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas.
    Journal of the National Cancer Institute, 2004, Mar-17, Volume: 96, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Azacitidine; Carrier Proteins; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Gene Deletion; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hydroxamic Acids; Membrane Proteins; Mutation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiolester Hydrolases; Transcription, Genetic

2004
HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells.
    Cancer research, 2004, Jul-15, Volume: 64, Issue:14

    Topics: Animals; Antigen Presentation; Antigens, Neoplasm; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Decitabine; DNA Methylation; Epitopes, T-Lymphocyte; Gene Expression Regulation, Neoplastic; Glioblastoma; gp100 Melanoma Antigen; Humans; Interferon-gamma; Melanoma-Specific Antigens; Membrane Glycoproteins; Neoplasm Proteins; Receptor, ErbB-2; RNA, Messenger; T-Lymphocytes, Cytotoxic

2004
Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction.
    Cancer research, 2005, Dec-15, Volume: 65, Issue:24

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Caspase 8; Caspases; Decitabine; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Histocompatibility Antigens Class I; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Glycoproteins; Mice; Mice, Nude; Middle Aged; Phosphoproteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2005
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.
    Cancer research, 2006, Aug-01, Volume: 66, Issue:15

    Topics: Azacitidine; Brain Neoplasms; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Humans; Hydroxamic Acids; Up-Regulation

2006
Downregulation of RUNX3 and TES by hypermethylation in glioblastoma.
    Oncogene, 2007, Jan-25, Volume: 26, Issue:4

    Topics: Azacitidine; Brain; Core Binding Factor Alpha 3 Subunit; Cytoskeletal Proteins; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Glioblastoma; Homeodomain Proteins; Humans; LIM Domain Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; Sequence Analysis, DNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Tumor Suppressor Proteins

2007
[Characterization of chromosomal rearrangements by in situ hybridization in glioblastoma].
    Bulletin du cancer, 1994, Volume: 81, Issue:5

    Topics: Azacitidine; Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; DNA, Neoplasm; DNA, Satellite; Glioblastoma; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Methylation; Middle Aged; Tumor Cells, Cultured

1994
Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation.
    Cancer research, 1996, May-15, Volume: 56, Issue:10

    Topics: Astrocytoma; Azacitidine; Base Sequence; Brain Chemistry; Brain Neoplasms; Carrier Proteins; Chromatin; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Methylation; Molecular Sequence Data; Neoplasm Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured

1996