azacitidine and Anemia, Sickle Cell

azacitidine has been researched along with Anemia, Sickle Cell in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (45.31)	18.7374
1990's	11 (17.19)	18.2507
2000's	19 (29.69)	29.6817
2010's	3 (4.69)	24.3611
2020's	2 (3.13)	2.80

Authors

Authors	Studies
Arlet, JB; Darnige, L; De Luna, G; Peyrard, T; Pouchot, J; Roueff, S	1
Atkins, C; Benowitz, AB; Butlin, R; Cockerill, M; Ennulat, D; Gilmartin, AG; Gore, ER; Groy, A; Halsey, W; Jordan, A; Kruger, RG; Long, ER; Luengo, J; McCabe, MT; McNulty, DE; Montoute, MN; Ogilvie, D; Pappalardi, M; Raoof, A; Rueda, L; Stowell, A; Waddell, I; Wu, Z	1
DeSimone, J; Engel, JD; Fada, S; Gordeuk, V; Gowhari, M; Hassan, J; Hsieh, M; Hsu, LL; Ibanez, V; Jacobberger, J; Krauz, L; Lavelle, D; Molokie, R; Ng, KP; Pacelli, D; Pacini, M; Phelps, M; Radivoyevitch, T; Ruiz, MA; Rump, M; Saraf, S; Saunthararajah, Y; Tisdale, JF; Woost, P	1
Ames, RS; Bee, WT; Benowitz, A; Erickson-Miller, CL; Gore, ER; Kallal, L; Li, H; Montoute, MN; Pope, AJ; Wu, Z; Xie, W; Zappacosta, F; Zeng, X	1
Roberts, I; Trompeter, S	1
Fathallah, H	1
Cappellini, MD; Musallam, KM; Sankaran, VG; Taher, AT	1
Steinberg, MH	3
Bressler, L; Chen, YH; DeSimone, J; Dorn, L; Gavazova, S; Hillery, CA; Hoffman, R; Lavelle, D; Molokie, R; Saunthararajah, Y	1
Cao, H	1
DeSimone, J; Lavelle, D; Saunthararajah, Y	1
DeSimone, J; Saunthararajah, Y	1
DeSimone, J	1
de Vos, D; van Overveld, W	1
Atweh, GF; Fathallah, H; Sutton, M	1
Aliyu, ZY; Kato, GJ; Tumblin, AR	1
Hatzimichael, EC; Makis, AC; Stebbing, J	1
Atweh, GF; Fathallah, H	1
DeSimone, J; Gowhari, M; Lavelle, D; Molokie, R; Saraf, S; Saunthararajah, Y; Sidhwani, S; Vara, S	1
Boyer, SH; Charache, S; Dover, GJ	1
Kolata, G	2
Orkin, SH	1
DeSimone, J; Heller, P; Ley, TJ; Nienhuis, AW; Noguchi, CT; Schechter, AN; Turner, PH	1
Boyer, S; Charache, S; Dover, G; Moyer, M; Smith, K; Talbot, CC	1
Boyer, SH; Charache, SH; Dover, GJ; Smith, KD; Talbot, CC	1
Cypress, GC; Nalbandian, RM	1
Adamson, JW	1
Benz, EJ	1
Alavi, JB	1
DeSimone, J; Heller, P	1
Charache, SH; Dover, GJ	1
Charache, S	5
Platt, OS	2
DeSimone, J; Heller, P; Lavelle, D	1
Fibach, E; Prasanna, P; Rodgers, GP; Samid, D	1
Pearson, HA	1
Bressler, L; DeSimone, J; Dorn, L; Hoffman, R; Koshy, M; Lavelle, D; Molokie, R; Talischy, N; van Overveld, W	1
Atweh, GF; Schechter, AN	1
Bressler, L; DeSimone, J; Dorn, L; Koshy, M; Lavelle, D; Molokie, R; Talischy, N	1
Ranney, HM	1
Nienhuis, AW; Stamatoyannopoulos, JA	1
Pallister, CJ	1
Boyer, SH; Charache, S; Dover, GJ; Nora, R	1
Boyer, SH; Charache, S; Dover, GJ; Moyer, M; Vogelsang, G	1
Galanello, R; Papayannopoulou, T; Stamatoyannopoulos, G; Veith, R	1
Boyer, S; Charache, S; Dover, GJ; Humphries, RK; Ley, T; Nienhuis, A; Young, N	1
Charache, S; Dover, GJ; Humphries, RK; Ley, TJ; Moore, JG; Nienhuis, AW; Young, NS	1
Charache, S; Dover, GJ	3
Dover, G; Hope, S; Miller, BA; Nathan, DG; Platt, O	1
Noguchi, CT; Rodgers, GP; Schechter, AN; Serjeant, G	1
Rokicka-Piotrowicz, M	1
Jones, PA	1
Charache, S; Dover, G; Humphries, RK; Ley, T; Moore, JG; Nienhuis, AW; Young, NS	1

Reviews

27 review(s) available for azacitidine and Anemia, Sickle Cell

Article	Year
Haemoglobin F modulation in childhood sickle cell disease. British journal of haematology, 2009, Volume: 144, Issue:3 Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Butyrates; Child; Clinical Trials as Topic; Decitabine; Fetal Hemoglobin; Humans; Hydroxyurea; Stroke; Young Adult	2009
Clinical experience with fetal hemoglobin induction therapy in patients with β-thalassemia. Blood, 2013, Mar-21, Volume: 121, Issue:12 Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; beta-Thalassemia; DNA Methylation; Fetal Hemoglobin; Humans; Hydroxyurea; Professional Practice; Treatment Outcome; Up-Regulation	2013
Therapies to increase fetal hemoglobin in sickle cell disease. Current hematology reports, 2003, Volume: 2, Issue:2 Topics: Anemia, Sickle Cell; Azacitidine; Butyrates; Cytokines; Decitabine; Drug Therapy, Combination; Fetal Hemoglobin; Humans; Hydroxyurea	2003
Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716. Drugs in R&D, 2003, Volume: 4, Issue:6 Topics: Anemia, Sickle Cell; Antineoplastic Agents; Azacitidine; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Decitabine; Humans; Leukemia; Lung Neoplasms; Male; Prostatic Neoplasms	2003
Pharmacological induction of fetal hemoglobin synthesis using histone deacetylase inhibitors. Hematology (Amsterdam, Netherlands), 2004, Volume: 9, Issue:3 Topics: Anemia, Sickle Cell; Azacitidine; beta-Thalassemia; Enzyme Inhibitors; Fetal Hemoglobin; Histone Deacetylase Inhibitors; Humans; Hydroxyurea	2004
DNA hypo-methylating agents and sickle cell disease. British journal of haematology, 2004, Volume: 126, Issue:5 Topics: Anemia, Sickle Cell; Azacitidine; Decitabine; DNA Methylation; DNA Modification Methylases; Fetal Hemoglobin; Gene Deletion; Humans; Randomized Controlled Trials as Topic	2004
Clinical studies with fetal hemoglobin-enhancing agents in sickle cell disease. Seminars in hematology, 2004, Volume: 41, Issue:4 Suppl 6 Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; DNA Methylation; DNA Modification Methylases; Fetal Hemoglobin; Humans	2004
Pharmacological induction of fetal hemoglobin: Why haven't we been more successful in thalassemia? Annals of the New York Academy of Sciences, 2005, Volume: 1054 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Combined Modality Therapy; Drug Approval; Drug Evaluation; Drug Evaluation, Preclinical; Erythropoiesis; Fetal Hemoglobin; Gene Expression; Gene Expression Regulation; Globins; Humans; Hydroxyurea; Iron; K562 Cells; Models, Animal; Papio; Thalassemia; Transfusion Reaction; United States; United States Food and Drug Administration	2005
Pathophysiologically based drug treatment of sickle cell disease. Trends in pharmacological sciences, 2006, Volume: 27, Issue:4 Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Antisickling Agents; Azacitidine; Cell Adhesion; Drug Therapy, Combination; Endothelium, Vascular; Erythrocytes; Fetal Hemoglobin; Gene Expression Regulation; Hemoglobin, Sickle; Humans; Hydroxyurea; K Cl- Cotransporters; Pyrrolidonecarboxylic Acid; Randomized Controlled Trials as Topic; Symporters	2006
The genomics of new drugs in sickle cell disease. Pharmacogenomics, 2006, Volume: 7, Issue:6 Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Butyrates; Decitabine; Drug Resistance; Humans; Hydroxyurea; Nitric Oxide; Pharmacogenetics; Phenotype; Poloxamer; Polymorphism, Genetic; Sulfasalazine; Toxicogenetics	2006
Induction of fetal hemoglobin in the treatment of sickle cell disease. Hematology. American Society of Hematology. Education Program, 2006 Topics: Anemia, Sickle Cell; Azacitidine; Butyrates; Decitabine; Fetal Hemoglobin; Gene Expression Regulation; Humans; Hydroxyurea	2006
Sickle cell anemia. Pathophysiology and treatment. The Medical clinics of North America, 1984, Volume: 68, Issue:3 Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Azepines; Blood Transfusion; Cerebrovascular Disorders; Child; Child, Preschool; Female; Folic Acid; Humans; Male; Phenothiazines; Pneumococcal Infections; Pregnancy; Pregnancy Complications, Hematologic; Priapism; Urea; Vaccination	1984
5-Azacytidine and fetal hemoglobin. American journal of hematology, 1984, Volume: 17, Issue:4 Topics: Adult; Anemia, Sickle Cell; Animals; Azacitidine; Carcinogens; Disease Models, Animal; DNA; Fetal Hemoglobin; Gene Expression Regulation; Humans; Male; Methylation; Middle Aged; Papio; Thalassemia	1984
Review: the sickle hemoglobinopathies--genetic analyses of common phenocopies and new molecular approaches to treatment. The American journal of the medical sciences, 1984, Volume: 288, Issue:4 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Fetal Hemoglobin; Gene Expression Regulation; Genotype; Globins; Hemoglobin A; Hemoglobin A2; Hemoglobin SC Disease; Hemoglobin, Sickle; Humans; Phenotype; Sickle Cell Trait; Thalassemia	1984
Fetal hemoglobin reactivation in baboon and man: a short perspective. American journal of hematology, 1993, Volume: 42, Issue:1 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Butyrates; Butyric Acid; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Papio	1993
Pharmacological modification of hemoglobin F expression in sickle cell anemia: an update on hydroxyurea studies. Experientia, 1993, Feb-15, Volume: 49, Issue:2 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythrocytes; Fetal Hemoglobin; Gene Expression; Humans; Hydroxyurea	1993
Pharmacologic manipulation of fetal hemoglobin levels in sickle cell diseases and thalassemia: promise and reality. Advances in pediatrics, 1996, Volume: 43 Topics: Anemia, Sickle Cell; Antineoplastic Agents; Antisickling Agents; Azacitidine; beta-Thalassemia; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Phenylbutyrates	1996
Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease. Current opinion in hematology, 2001, Volume: 8, Issue:2 Topics: Anemia, Sickle Cell; Azacitidine; Butyrates; Decitabine; Fetal Hemoglobin; Humans; Hydroxyurea	2001
The spectrum of sickle cell disease. Hospital practice (Office ed.), 1992, Jan-15, Volume: 27, Issue:1 Topics: Adolescent; Adult; Anemia, Sickle Cell; Azacitidine; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 16; Female; Fluid Therapy; Genotype; Globins; Hemoglobin, Sickle; Humans; Hydroxyurea; Male; Oxygen Inhalation Therapy; Polymorphism, Genetic; Pregnancy	1992
Therapeutic approaches to hemoglobin switching in treatment of hemoglobinopathies. Annual review of medicine, 1992, Volume: 43 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Hemoglobinopathies; Humans; Hydroxyurea; Thalassemia	1992
Fetal hemoglobin, sickling, and sickle cell disease. Advances in pediatrics, 1990, Volume: 37 Topics: Adolescent; Adult; Anemia, Sickle Cell; Animals; Azacitidine; Child; Fetal Hemoglobin; Humans; Hydroxyurea; Infant, Newborn; Papio; Sheep	1990
Hydroxyurea as treatment for sickle cell anemia. Hematology/oncology clinics of North America, 1991, Volume: 5, Issue:3 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythropoietin; Humans; Hydroxyurea	1991
Pharmacologic stimulation of Hb F in patients with sickle cell anemia. Progress in clinical and biological research, 1985, Volume: 191 Topics: Anemia, Sickle Cell; Azacitidine; Cell Survival; Erythropoiesis; Fetal Hemoglobin; Homozygote; Humans; Hydroxyurea; Kinetics; Reticulocytes; Stem Cells	1985
Levels of fetal hemoglobin necessary for treatment of sickle cell disease. The New England journal of medicine, 1988, Jan-14, Volume: 318, Issue:2 Topics: Anemia, Sickle Cell; Azacitidine; Fetal Hemoglobin; Humans; Hydroxyurea; Polymers	1988
Chemotherapy and hemoglobin F synthesis in sickle cell disease. Annals of the New York Academy of Sciences, 1989, Volume: 565 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Clinical Trials as Topic; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Interleukin-3; Papio; Recombinant Proteins	1989
[Fetal hemoglobin]. Postepy higieny i medycyny doswiadczalnej, 1989, Volume: 43, Issue:5-6 Topics: Amino Acid Sequence; Amino Acids; Anemia, Sickle Cell; Azacitidine; Fetal Blood; Fetal Hemoglobin; Humans; Molecular Sequence Data; Stimulation, Chemical; Thalassemia	1989
Altering gene expression with 5-azacytidine. Cell, 1985, Volume: 40, Issue:3 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Cell Differentiation; Cell Line; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Fetal Hemoglobin; Gene Expression Regulation; Genes; Genes, Regulator; Methylation; Mutation; Neoplasms; Thalassemia; Thymidine Kinase	1985

Trials

9 trial(s) available for azacitidine and Anemia, Sickle Cell

Article	Year
Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study. PLoS medicine, 2017, Volume: 14, Issue:9 Topics: Adult; Anemia, Sickle Cell; Azacitidine; Decitabine; Drug Therapy, Combination; Enzyme Inhibitors; Epigenesis, Genetic; Female; Fetal Hemoglobin; Gene Expression Regulation; Gene Silencing; Humans; Male; Middle Aged; Tetrahydrouridine; Treatment Outcome; Young Adult	2017
Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease. Blood, 2003, Dec-01, Volume: 102, Issue:12 Topics: Adult; Anemia, Sickle Cell; Azacitidine; Biomarkers; Blood Coagulation; Bone Marrow; Cell Adhesion; Cell Differentiation; Decitabine; DNA Methylation; Endothelium, Vascular; Erythrocytes; Female; Fetal Hemoglobin; Hematopoiesis; Humans; Inflammation; Laminin; Male; Middle Aged; Thrombospondins; Vascular Diseases	2003
Molecular genetics of the sickling syndromes: evolution of new strategies for improved diagnosis. The American journal of pediatric hematology/oncology, 1984,Spring, Volume: 6, Issue:1 Topics: Anemia, Sickle Cell; Azacitidine; Base Composition; Chromosome Mapping; Clinical Trials as Topic; DNA Restriction Enzymes; DNA, Recombinant; Gene Expression Regulation; Genes; Globins; Hemoglobin SC Disease; Humans; Prenatal Diagnosis; Thalassemia	1984
Experimental therapy of sickle cell disease. Use of hydroxyurea. The American journal of pediatric hematology/oncology, 1994, Volume: 16, Issue:1 Topics: Anemia, Sickle Cell; Azacitidine; Bone Marrow Transplantation; Humans; Hydroxyurea	1994
Pharmacological modification of hemoglobin F expression in sickle cell anemia: an update on hydroxyurea studies. Experientia, 1993, Feb-15, Volume: 49, Issue:2 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythrocytes; Fetal Hemoglobin; Gene Expression; Humans; Hydroxyurea	1993
Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia. Blood, 2002, Jun-01, Volume: 99, Issue:11 Topics: Anemia, Sickle Cell; Azacitidine; Decitabine; DNA Modification Methylases; Fetal Hemoglobin; Humans; Injections, Subcutaneous; Leukocyte Count; Neutrophils; Reticulocyte Count; Time Factors	2002
Hydroxyurea as treatment for sickle cell anemia. Hematology/oncology clinics of North America, 1991, Volume: 5, Issue:3 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythropoietin; Humans; Hydroxyurea	1991
Progress toward increasing fetal hemoglobin production in man: experience with 5-azacytidine and hydroxyurea. Annals of the New York Academy of Sciences, 1985, Volume: 445 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Bone Marrow; Cells, Cultured; Clinical Trials as Topic; Erythropoiesis; Fetal Hemoglobin; Humans; Hydroxyurea; Reticulocytes; Thalassemia	1985
Chemotherapy and hemoglobin F synthesis in sickle cell disease. Annals of the New York Academy of Sciences, 1989, Volume: 565 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Clinical Trials as Topic; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Interleukin-3; Papio; Recombinant Proteins	1989

Other Studies

31 other study(ies) available for azacitidine and Anemia, Sickle Cell

Article	Year
Usefulness of azacitidine therapy in a sickle cell disease patient with myelodysplastic syndrome. Annals of hematology, 2020, Volume: 99, Issue:3 Topics: Anemia, Sickle Cell; Azacitidine; Humans; Male; Middle Aged; Myelodysplastic Syndromes	2020
Haematologica, 2021, 07-01, Volume: 106, Issue:7 Topics: Anemia, Sickle Cell; Animals; Azacitidine; DNA Methylation; Fetal Hemoglobin; gamma-Globins; Mice	2021
Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells. Journal of biomolecular screening, 2013, Volume: 18, Issue:10 Topics: Anemia, Sickle Cell; Azacitidine; Bone Marrow Cells; Butyric Acid; Cell Survival; Decitabine; DNA Modification Methylases; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Erythroid Precursor Cells; gamma-Globins; Histone Deacetylase Inhibitors; Humans; Primary Cell Culture; Transcriptional Activation	2013
DNA hypomethylation therapies and hemoglobin disorders. [An interview with Hassana Fathallah by H&O]. Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11 Topics: Anemia, Sickle Cell; Antineoplastic Agents; Azacitidine; beta-Thalassemia; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Fetal Hemoglobin; Histone Acetyltransferases; Humans; Hydroxyurea	2008
Approaches to the reactivation of hemoglobin F as a treatment for sickle cell disease. Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:1 Topics: Acetylation; Anemia, Sickle Cell; Azacitidine; Clinical Trials as Topic; CpG Islands; Decitabine; Disease Management; DNA Methylation; Erythrocytes, Abnormal; Fetal Hemoglobin; Gene Silencing; Globins; Hemoglobin, Sickle; Histone Deacetylase Inhibitors; Humans; Hydroxyurea; Phenylbutyrates; Protein Processing, Post-Translational; Up-Regulation	2004
Decitabine: a historical review of the development of an epigenetic drug. Annals of hematology, 2005, Volume: 84 Suppl 1 Topics: Anemia, Sickle Cell; Azacitidine; Decitabine; DNA Modification Methylases; Drug Design; Epigenesis, Genetic; History, 20th Century; History, 21st Century; Humans; Myelodysplastic Syndromes; Transplantation Conditioning	2005
Current therapy of sickle cell disease. Haematologica, 2006, Volume: 91, Issue:1 Topics: Acetamides; Anemia, Sickle Cell; Azacitidine; Butyrates; Decitabine; Erythrocyte Transfusion; Humans; Hydroxyurea; Nitric Oxide; Trityl Compounds	2006
Clinical effectiveness of decitabine in severe sickle cell disease. British journal of haematology, 2008, Volume: 141, Issue:1 Topics: Adult; Anemia, Sickle Cell; Azacitidine; Decitabine; DNA Modification Methylases; Enzyme Inhibitors; Female; Humans; Middle Aged; Treatment Outcome	2008
Increasing fetal hemoglobin in sickle cell disease: comparisons of 5-azacytidine (subcutaneous or oral) with hydroxyurea. Transactions of the Association of American Physicians, 1984, Volume: 97 Topics: Adult; Anemia, Sickle Cell; Azacitidine; Fetal Hemoglobin; Humans; Hydroxyurea; Middle Aged; Reticulocytes	1984
Fetal hemoglobin genes turned on in adults. Science (New York, N.Y.), 1982, Dec-24, Volume: 218, Issue:4579 Topics: Adult; Anemia, Sickle Cell; Azacitidine; Fetal Hemoglobin; Hemoglobin, Sickle; Humans; Male; Thalassemia	1982
Controlling the fetal globin switch in man. Nature, 1983, Jan-13, Volume: 301, Issue:5896 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Fetal Hemoglobin; Gene Expression Regulation; Humans; Papio; Thalassemia	1983
5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia. Blood, 1983, Volume: 62, Issue:2 Topics: Adult; Anemia, Sickle Cell; Azacitidine; Bone Marrow Cells; DNA; Erythrocytes; Fetal Hemoglobin; Globins; Humans; Male; Methylation; Middle Aged; RNA, Messenger; Thalassemia	1983
Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex. Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:15 Topics: Adult; Anemia, Sickle Cell; Azacitidine; DNA; DNA Restriction Enzymes; Fetal Hemoglobin; Genes; Globins; Humans; Male; Methylation; Nucleic Acid Hybridization	1983
Globin gene studies create a puzzle. Science (New York, N.Y.), 1984, Feb-03, Volume: 223, Issue:4635 Topics: Anemia, Sickle Cell; Azacitidine; Cell Differentiation; Cytarabine; DNA; Erythropoiesis; Fetal Hemoglobin; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Hydroxyurea; Interphase; Methylation	1984
5-Azacytidine increases fetal hemoglobin production in a patient with sickle cell disease. Progress in clinical and biological research, 1983, Volume: 134 Topics: Adult; Anemia, Sickle Cell; Azacitidine; DNA (Cytosine-5-)-Methyltransferases; Fetal Hemoglobin; Gene Expression Regulation; Globins; Hemoglobin, Sickle; Humans; Male; Methylation	1983
Gene switching -- a new therapeutic epoch: discussion paper. Journal of the Royal Society of Medicine, 1984, Volume: 77, Issue:3 Topics: Anemia, Sickle Cell; Azacitidine; Female; Fetal Blood; Fetal Hemoglobin; Gene Expression Regulation; Genes; Hemoglobins; Humans; Operon; Pregnancy; Thalassemia	1984
Hemoglobin--from F to A, and back. The New England journal of medicine, 1984, Apr-05, Volume: 310, Issue:14 Topics: Anemia, Sickle Cell; Azacitidine; DNA; Fetal Hemoglobin; Humans; Hydroxyurea; Methylation; Thalassemia	1984
The effects of variable doses of 5-azacytidine on fetal hemoglobin production in sickle cell anemia. Progress in clinical and biological research, 1984, Volume: 165 Topics: Anemia, Sickle Cell; Azacitidine; Bone Marrow; Fetal Hemoglobin; Humans	1984
Sickle cell paths converge on hydroxyurea. Nature medicine, 1995, Volume: 1, Issue:4 Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Child; Fetal Hemoglobin; Hemoglobin, Sickle; Humans; Hydroxyurea; Mutation	1995
Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia. Blood, 1993, Oct-01, Volume: 82, Issue:7 Topics: Anemia, Sickle Cell; Azacitidine; beta-Thalassemia; Blotting, Northern; Butyrates; Butyric Acid; Cell Division; Cells, Cultured; DNA Probes; Erythrocytes; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Kinetics; Phenylacetates; Phenylbutyrates; Reference Values	1993
2-deoxy 5-azacytidine and fetal hemoglobin induction in sickle cell anemia. Blood, 2000, Oct-01, Volume: 96, Issue:7 Topics: Adolescent; Adult; Anemia, Sickle Cell; Azacitidine; Blood Cell Count; Cohort Studies; Decitabine; Erythrocyte Count; Female; Fetal Hemoglobin; Globins; Humans; Hydroxyurea; Male; Middle Aged; Neutrophils; Platelet Count; Reticulocytes	2000
A 'crisis' that can be overcome: management of sickle cell disease. Professional nurse (London, England), 1992, Volume: 7, Issue:8 Topics: Anemia, Sickle Cell; Azacitidine; Humans	1992
5-Azacytidine increases HbF production and reduces anemia in sickle cell disease: dose-response analysis of subcutaneous and oral dosage regimens. Blood, 1985, Volume: 66, Issue:3 Topics: Administration, Oral; Adult; Anemia, Sickle Cell; Azacitidine; Drug Administration Schedule; Erythrocyte Count; Erythrocyte Indices; Erythropoiesis; Fetal Hemoglobin; Hemoglobins; Humans; Injections, Subcutaneous; Middle Aged; Pain; Reticulocytes	1985
Pharmacologic manipulation of fetal hemoglobin synthesis. Progress in clinical and biological research, 1985, Volume: 191 Topics: Anemia, Sickle Cell; Azacitidine; DNA Replication; Erythropoiesis; Fetal Hemoglobin; Gene Expression Regulation; Globins; Humans; Hydroxyurea	1985
Chemotherapy to increase fetal hemoglobin in patients with sickle cell anemia. The American journal of pediatric hematology/oncology, 1985,Fall, Volume: 7, Issue:3 Topics: Anemia, Sickle Cell; Azacitidine; Cytarabine; Fetal Hemoglobin; Humans; Hydroxyurea; Kinetics; Thalassemia	1985
Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production. Blood, 1986, Volume: 67, Issue:3 Topics: Anemia, Sickle Cell; Azacitidine; Erythropoiesis; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Reticulocytes	1986
Advances in the understanding of sickle cell anemia. Hospital practice (Office ed.), 1986, Feb-15, Volume: 21, Issue:2 Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Cyanates; Erythrocyte Deformability; Erythrocytes, Abnormal; Genetic Engineering; Glyceraldehyde; Hemoglobin, Sickle; Humans; Mechlorethamine; Renal Dialysis	1986
The effect of increased fetal hemoglobin production on the frequency of vaso-occlusive crisis in sickle cell disease. Progress in clinical and biological research, 1987, Volume: 240 Topics: Anemia, Sickle Cell; Azacitidine; Centrifugation, Density Gradient; Erythrocytes; Fetal Hemoglobin; Humans; Hydroxyurea; Infarction; Pain	1987
Influence of hydroxyurea on fetal hemoglobin production in vitro. Blood, 1987, Volume: 70, Issue:6 Topics: Anemia, Sickle Cell; Animals; Azacitidine; Cells, Cultured; Erythroblasts; Erythropoiesis; Fetal Hemoglobin; Hemoglobins; Humans; Hydroxyurea	1987
Increasing fetal hemoglobin production in sickle cell disease: results of clinical trials. Progress in clinical and biological research, 1987, Volume: 251 Topics: Anemia, Sickle Cell; Azacitidine; DNA; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Methylation; Reticulocytes	1987
5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin. The Journal of clinical investigation, 1985, Volume: 75, Issue:2 Topics: Adult; Anemia, Sickle Cell; Azacitidine; Erythrocytes; Erythropoiesis; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Middle Aged; RNA, Messenger; Thalassemia	1985