azacitidine and Aging

azacitidine has been researched along with Aging in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's2 (8.33)18.2507
2000's3 (12.50)29.6817
2010's14 (58.33)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Chang, F; Li, Y; Liang, M; Rong, J; Zhong, H; Zhou, R; Zhu, C1
Ali, A; Montoro, J; Raza, A; Yerlikaya, A1
Sangeeta, K; Yenugu, S1
Bachmann, A; Culmes, M; De Sousa, PA; Ehnert, S; Nussler, AK; Pelisek, J; Rahmanian-Schwarz, A; Schyschka, L; Seeliger, C; Stöckle, U; Wang, Z; Yan, X1
Affinito, O; Belardo, C; Chiariotti, L; Cristino, L; De Novellis, V; Errico, F; Florio, E; Imperatore, R; Keller, S; Luongo, L; Maddaloni, G; Maione, S; Migliarini, S; Nuzzo, T; Pasqualetti, M; Pollegioni, L; Punzo, D; Sacchi, S; Sisalli, MJ; Usiello, A1
Dasgupta, C; Halavi, S; Hartman, RE; Li, Y; Ma, Q; Xiao, D; Zhang, L1
Johnson, RW; Lawson, MA; Matt, SM1
Chubinskaya, S; Im, HJ; Loeser, RF; Lu, Q; Richardson, B1
Dicato, M; Diederich, M; Foliguet, B; Ghelfi, J; Grandjenette, C; Karius, T; Schnekenburger, M1
Croy, BA; Hatta, K; Jenkins, EC; Kerkel, K; Kratz, A; Mayeux, RP; Minden, M; Murty, V; Pang, D; Salas, M; Schork, NJ; Schupf, N; Silverman, W; Torkamani, A; Tycko, B; Zigman, WB1
Aucagne, R; Bastie, JN; Bataille, A; Delva, L; Droin, N; Fenaux, P; Hammann, A; Lagrange, B; Largeot, A; Losson, R; Martin, L; Paggetti, J; Solary, E; Yan, KP1
Fischer-Posovszky, P; Gausmann, U; Huse, K; Nebel, A; Platzer, M; Reichwald, K; Rosenstiel, P; Stepanow, S; Wabitsch, M1
Alvarado, S; Anderson, KM; Dashwood, T; Haglund, L; Millecamps, M; Ouellet, J; Stone, LS; Szyf, M; Tajerian, M1
Kobyliansky, E; Mizrahi, L; Savion, S; Shahar, R; Toder, V; Torchinsky, A1
Kang, KS1
Aota, K; Azuma, M; Kani, K; Momota, Y; Motegi, K; Takano, H; Yamamura, Y; Yamanoi, T1
Akintola, AD; Burghardt, RC; Catania, JM; Chen, G; Crislip, ZL; Parrish, AR; Zimmer, WE1
Adams, RL; Burdon, RH1
Chiu, JF; Cook, JR1
Davidson, JM; Giro, MG; Hill, KE; Luvalle, PA; Ruckman, JL1
Gartler, SM; Goldman, MA1
de Carvalho, CV; Payão, SL; Smith, MA1
Billmire, DF; Keefer, RC; MacNamara, DJ; Schumm, DE; Webb, TE1
Axelman, J; Beggs, AH; Migeon, BR1

Reviews

3 review(s) available for azacitidine and Aging

ArticleYear
Improving Treatment for Myelodysplastic Syndromes Patients.
    Current treatment options in oncology, 2018, 10-25, Volume: 19, Issue:12

    Topics: Aging; Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; Enzyme Inhibitors; Humans; Lenalidomide; Myelodysplastic Syndromes; Stem Cell Transplantation; Transplantation, Homologous

2018
DNA methylation in eukaryotes.
    CRC critical reviews in biochemistry, 1982, Volume: 13, Issue:4

    Topics: 5-Methylcytosine; Aging; Animals; Azacitidine; Base Sequence; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Gene Expression Regulation; Globins; Methylation; Nucleic Acid Conformation; Ovalbumin

1982
Reactivation of inactive X-linked genes.
    Developmental genetics, 1994, Volume: 15, Issue:6

    Topics: Aging; Animals; Azacitidine; Cell Fusion; Dosage Compensation, Genetic; Gene Expression Regulation, Developmental; Germ Cells; Humans; Methylation; X Chromosome

1994

Other Studies

21 other study(ies) available for azacitidine and Aging

ArticleYear
Prenatal Stress Leads to the Altered Maturation of Corticostriatal Synaptic Plasticity and Related Behavioral Impairments Through Epigenetic Modifications of Dopamine D2 Receptor in Mice.
    Molecular neurobiology, 2021, Volume: 58, Issue:1

    Topics: Aging; Animals; Azacitidine; Behavior, Animal; Corpus Striatum; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Dopamine; Down-Regulation; Epigenesis, Genetic; Long-Term Potentiation; Long-Term Synaptic Depression; Mice, Inbred C57BL; Neuronal Plasticity; Promoter Regions, Genetic; Receptors, Dopamine D2; Receptors, Metabotropic Glutamate; Signal Transduction; Stress, Physiological

2021
Male reproductive tract antimicrobial expression in the extremes of ages of rats.
    Gene, 2019, Aug-20, Volume: 710

    Topics: Aging; Animals; Azacitidine; beta-Defensins; Gene Expression Regulation; Genitalia, Male; Glycopeptides; Hydroxamic Acids; Lipopolysaccharides; Male; Rats; Rats, Wistar

2019
5-azacytidine improves the osteogenic differentiation potential of aged human adipose-derived mesenchymal stem cells by DNA demethylation.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Adipose Tissue, White; Aging; Azacitidine; Cell Differentiation; Cell Proliferation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression; Humans; Mesenchymal Stem Cells; Osteocalcin; Osteogenesis; Proto-Oncogene Proteins; Sp7 Transcription Factor; Transcription Factors

2014
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-09, Volume: 36, Issue:10

    Topics: Age Factors; Aging; Animals; Animals, Newborn; Azacitidine; Brain; Cell Death; D-Aspartate Oxidase; D-Aspartic Acid; Decitabine; Embryo, Mammalian; Enzyme Inhibitors; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Promoter Regions, Genetic; Receptors, N-Methyl-D-Aspartate; RNA, Messenger

2016
Inhibition of DNA Methylation in the Developing Rat Brain Disrupts Sexually Dimorphic Neurobehavioral Phenotypes in Adulthood.
    Molecular neurobiology, 2017, Volume: 54, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Azacitidine; Behavior, Animal; Body Weight; Brain; Brain-Derived Neurotrophic Factor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Female; Male; Maze Learning; Organ Size; Phenotype; Promoter Regions, Genetic; Rats, Sprague-Dawley; Receptor, trkB; RNA, Messenger; Rotarod Performance Test; Sex Characteristics

2017
Aging and peripheral lipopolysaccharide can modulate epigenetic regulators and decrease IL-1β promoter DNA methylation in microglia.
    Neurobiology of aging, 2016, Volume: 47

    Topics: Aging; Animals; Azacitidine; DNA Methylation; Epigenesis, Genetic; Gene Expression; Interleukin-1beta; Lipopolysaccharides; Mice, Inbred C57BL; Microglia; Promoter Regions, Genetic

2016
Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage.
    Osteoarthritis and cartilage, 2009, Volume: 17, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Azacitidine; Bone Morphogenetic Protein 7; Cartilage, Articular; Cells, Cultured; Chondrocytes; DNA Methylation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Insulin-Like Growth Factor I; Middle Aged; Promoter Regions, Genetic; Receptor, IGF Type 1; Young Adult

2009
Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy.
    Biochemical pharmacology, 2011, Feb-01, Volume: 81, Issue:3

    Topics: Aging; Antimetabolites, Antineoplastic; Apoptosis; Autophagy; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Survival; Decitabine; DNA Methylation; Drug Synergism; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive

2011
Altered DNA methylation in leukocytes with trisomy 21.
    PLoS genetics, 2010, Nov-18, Volume: 6, Issue:11

    Topics: Adult; Aging; Azacitidine; Child; Child, Preschool; DNA Methylation; Down Syndrome; Gene Expression Profiling; Gene Expression Regulation; Humans; Infant; Jurkat Cells; Leukocyte Count; Leukocytes; Lymphocytes; Nerve Tissue Proteins; Nod2 Signaling Adaptor Protein; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; RNA, Messenger; Sequence Analysis, DNA; Sulfites

2010
Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia.
    The Journal of clinical investigation, 2011, Volume: 121, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Animals; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Cell Differentiation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Leukemic; Genes, Tumor Suppressor; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia, Myelomonocytic, Chronic; Male; Mice; Mice, Knockout; Middle Aged; Molecular Sequence Data; Neoplasm Proteins; Promoter Regions, Genetic; Receptor, Macrophage Colony-Stimulating Factor; Specific Pathogen-Free Organisms; Transcription Factors

2011
Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Adult; Aged; Aging; Alleles; Azacitidine; Body Mass Index; Cell Line; CpG Islands; DNA Methylation; Gene Expression Regulation; Genome, Human; Humans; Male; Middle Aged; Receptors, Somatostatin; RNA, Messenger; Young Adult

2011
DNA methylation of SPARC and chronic low back pain.
    Molecular pain, 2011, Aug-25, Volume: 7

    Topics: Adult; Aging; Animals; Azacitidine; Behavior, Animal; Chronic Pain; DNA Methylation; Female; Gene Expression Regulation; Gene Silencing; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Low Back Pain; Male; Mice; Mice, Inbred C57BL; Osteonectin; Promoter Regions, Genetic

2011
Bone loss in adult offspring induced by low-dose exposure to teratogens.
    Journal of bone and mineral metabolism, 2012, Volume: 30, Issue:3

    Topics: Acid Phosphatase; Aging; Animals; Apoptosis; Azacitidine; Bone Resorption; Embryo, Mammalian; Female; Femur; Gene Expression Profiling; Gene Expression Regulation, Developmental; Hindlimb; Isoenzymes; Limb Buds; Mice; Mice, Inbred ICR; MicroRNAs; Osteoblasts; Osteogenesis; Osteoprotegerin; Pregnancy; Prenatal Exposure Delayed Effects; RANK Ligand; Reproduction; Tartrate-Resistant Acid Phosphatase; Teratogens; X-Ray Microtomography

2012
The secret lives of stem cells: unraveling the molecular basis of stem cell aging.
    Cell cycle (Georgetown, Tex.), 2011, Dec-15, Volume: 10, Issue:24

    Topics: Aging; Azacitidine; Cell Differentiation; Cellular Senescence; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Epigenesis, Genetic; Humans; Stem Cells; Umbilical Cord

2011
DNA demethylating agent decitabine increases AQP5 expression and restores salivary function.
    Journal of dental research, 2012, Volume: 91, Issue:6

    Topics: Aging; Animals; Aquaporin 5; Azacitidine; Cell Membrane Permeability; Decitabine; DNA Methylation; DNA Modification Methylases; Female; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Models, Animal; Promoter Regions, Genetic; Saliva; Salivary Glands; Salivation; Specific Pathogen-Free Organisms; Xerostomia

2012
Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:1

    Topics: Aging; Animals; Azacitidine; Base Sequence; Cadherins; Cells, Cultured; Cytosine; Decitabine; DNA; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Guanine; Kidney; Liver; Male; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Rats, Inbred F344

2008
Effect of 5-azacytidine on rat liver alpha-fetoprotein gene expression.
    Biochemical and biophysical research communications, 1983, Nov-15, Volume: 116, Issue:3

    Topics: Aging; alpha-Fetoproteins; Animals; Azacitidine; Cytosol; DNA; Genes; Kinetics; Liver; Nucleic Acid Hybridization; Plasmids; Rats; Rats, Inbred Strains; RNA; Transcription, Genetic

1983
Phenotypic stability and variation in cells of the porcine aorta: collagen and elastin production.
    Matrix biology : journal of the International Society for Matrix Biology, 1994, Volume: 14, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Aorta; Azacitidine; Cells, Cultured; Collagen; Elastin; Embryo, Mammalian; Extracellular Matrix; Muscle, Smooth, Vascular; Phenotype; Swine; Time Factors

1994
DNA methylation, ageing and ribosomal genes activity.
    Biogerontology, 2000, Volume: 1, Issue:4

    Topics: Adult; Aged; Aging; Alzheimer Disease; Azacitidine; Cells, Cultured; Chromosomes, Human, Pair 22; DNA Methylation; DNA, Ribosomal; Humans; Ribosomes; Transcription, Genetic

2000
Early temporal changes in the uridine kinase isozyme profile of the Novikoff hepatoma in response to 5-azacytidine treatment.
    Biochemical pharmacology, 1975, Jul-15, Volume: 24, Issue:13-14

    Topics: Aging; Animals; Azacitidine; Carcinoma, Hepatocellular; DNA Replication; Dose-Response Relationship, Drug; Drug Resistance; Female; Isoenzymes; Liver Neoplasms; Neoplasms, Experimental; Phosphotransferases; Rats; Thymidine; Time Factors; Tritium; Uridine Kinase

1975
Effect of ageing on reactivation of the human X-linked HPRT locus.
    Nature, 1988, Sep-01, Volume: 335, Issue:6185

    Topics: Aging; Azacitidine; Decitabine; Dosage Compensation, Genetic; Female; Heterozygote; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Skin; X Chromosome

1988