azacitidine has been researched along with Adenocarcinoma Of Kidney in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 17 (36.17) | 29.6817 |
| 2010's | 29 (61.70) | 24.3611 |
| 2020's | 1 (2.13) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, Z; Wang, W; Zuo, Y | 1 |
| Li, X; Yu, Q | 1 |
| Carew, JS; Espitia, C; Jones, TM; Nawrocki, ST; Wang, W | 1 |
| Chen, X; Huo, Y; Li, Y; Sun, J; Wang, T; Wang, W; Wu, J; Xi, W; Yang, A; Zheng, G | 1 |
| Ellinger, J; Müller, SC; Schiffgen, M; Schmidt, DH; von Rücker, A | 1 |
| Carter, JA; Górecki, DC; Hafizi, S; Ljungberg, B; Mein, CA | 1 |
| Konac, E; Menevse, S; Sozen, S; Varol, N; Yilmaz, A | 1 |
| Dong, D; Lu, D; Ma, WJ; Tian, XJ; Wen, JX; Zhang, J; Zhou, Y | 1 |
| Christensen, BC; David, JM; Lakshmikuttyamma, A; Owens, TA; Petrelli, NJ; Rajasekaran, AK; Selvakumar, P | 1 |
| Deng, Z; Lin, J; Matsuda, K; Miki, T; Nakamura, Y; Shuin, T; Tanikawa, C | 1 |
| Chen, G; Fan, Y; Jin, J; Li, L; Liu, Q; Tao, Q; Wang, L; Wang, Z; Xu, B; Ying, J; Zhang, L; Zhang, Q | 1 |
| Cao, JJ; Chen, KH; He, J; Li, MC; Li, WB; Liu, WJ; Sheng, X; Wang, DL; Zhao, XM | 1 |
| Cui, Y; Jin, J; Luo, C; Qi, Y; Xu, B; Ying, JM; Zhang, L; Zhang, Q | 1 |
| Mizokami, A; Nakamoto, M; Nakamura, R; Namiki, M; Ooi, A; Oyama, T; Tajiri, R | 1 |
| Arichi, N; Chang, I; Dahiya, R; Deng, G; Fukuhara, S; Hiraki, M; Hirata, H; Majid, S; Mitsui, Y; Saini, S; Shahryari, V; Shiina, H; Tanaka, Y; Yamamura, S; Yasumoto, H | 1 |
| He, C; Jiang, H; Xu, R; Zhao, X; Zhong, Z | 1 |
| Han, T; Liu, Y; Shang, D; Xu, X | 1 |
| Du, Z; Huang, S; Huang, X; Jin, J; Li, L; Tao, Q; Zhang, Q | 1 |
| Balsamo, T; Copetti, M; Costantini, M; De Salvo, L; Fabrizio, FP; Fazio, VM; Flammia, GP; Fontana, A; Gallucci, M; Graziano, P; Kok, K; la Torre, A; Muscarella, LA; Pantalone, A; Papalia, R; Paranita, F; Parente, P; Picardo, F; Poeta, L; Pompeo, V; Sentinelli, S; Simone, G; Sparaneo, A; Trombetta, D | 1 |
| Dahiya, R; Hinoda, Y; Hirata, H; Ishii, N; Kawakami, K; Kawamoto, K; Kikuno, N; Majid, S; Nakajima, K; Saini, S; Ueno, K; Yamamura, S | 1 |
| Iwata, H; Miyazawa, M; Sato, H; Takano, Y; Ueno, K; Virgona, N; Yano, T; Yano, Y | 1 |
| Chen, Y; Dahiya, R; Deng, G; Hinoda, Y; Hirata, H; Ishii, N; Kawamoto, K; Khatri, G; Kikuno, N; Majid, S; Nakajima, K; Saini, S; Ueno, K; Yamamura, S; Zaman, MS | 1 |
| Costa, VL; Duarte-Pereira, S; Henrique, R; Jerónimo, C; Lobo, F; Oliveira, J; Paiva, F; Patrício, P; Ramalho-Carvalho, J; Ribeiro, FR | 1 |
| Alcazar, O; Hu, Z; Lindner, D; Negrotto, S; Ng, KP; Rini, B; Saunthararajah, Y; Triozzi, P | 1 |
| Ichinomiya, S; Iwata, H; Okabe, H; Sato, H; Sekine, Y; Suzuki, R; Ueno, K; Yamada, R; Yanagihara, M; Yano, T | 1 |
| Costa, VL; Danielsen, SA; Eknaes, M; Henrique, R; Jerónimo, C; Lind, GE; Lothe, RA; Morais, A; Oliveira, J; Patrício, P; Teixeira, MR | 1 |
| Han, T; Liu, Y; Shang, D; Tian, Y; Xu, X | 1 |
| Daaka, Y; Gersey, Z; Kim, WJ | 1 |
| Colon-Otero, G; Cooper, SJ; Copland, JA; Grebe, SK; Kang, KH; Marlow, LA; Menefee, ME; Perez, EA; Tun, HW; von Roemeling, CA | 1 |
| Han, T; Shang, D; Tian, Y; Xu, X | 1 |
| Gordiyuk, VV; Kashuba, EV; Kashuba, VI; Kondratov, AG; Kvasha, SM; Romanenko, AM; Rynditch, AV; Stoliar, LA; Zabarovsky, ER; Zgonnyk, YM | 1 |
| Altomonte, M; Cattarossi, I; Colizzi, F; Coral, S; Engelsberg, A; Jager, E; Maio, M; Maraskovsky, E; Seliger, B; Sigalotti, L | 1 |
| Dahiya, R; Deguchi, M; Igawa, M; Kaneuchi, M; Nakajima, K; Shiina, H | 1 |
| Jang, T; Lee, C; Liu, VC; Park, I; Rubenstein, JN; Zhang, Q | 1 |
| Breault, JE; Carroll, PR; Dahiya, R; Deguchi, M; Enokida, H; Igawa, M; Kane, CJ; Nakagawa, M; Ribeiro-Filho, LA; Shiina, H; Terashima, M; Urakami, S | 1 |
| Biesová, Z; Jakubicková, L; Kettmann, R; Pastorek, J; Pastoreková, S | 1 |
| Daniel, PT; Dörken, B; Gillissen, B; Janz, M; Jung, K; Loening, S; Radetzki, S; Siebert, R; Stephan, C; Sturm, I | 1 |
| Al-Saleem, T; Cairns, P; Dulaimi, E; Hoffman, AM; Ibanez de Caceres, I; Uzzo, RG | 1 |
| Bae, SI; Beaulieu, N; Borden, EC; Cherkassky, L; Leaman, DW; Lindner, D; MacLeod, AR; Reu, FJ | 1 |
| Dressman, HK; Gollob, JA; Issa, JP; Jelinek, J; Moran, K; Peterson, BL; Richmond, T; Sciambi, CJ; Thoreson, M | 1 |
| Bates, SE; To, KK; Zhan, Z | 1 |
| Christoph, F; Kempkensteffen, C; Köllermann, J; Krause, H; Miller, K; Schostak, M; Schrader, M; Weikert, S | 1 |
| Ariga, T; Asamoto, M; Hagiwara, H; Hokaiwado, N; Nagashima, Y; Ohde, Y; Sato, H; Seki, T; Shirai, T; Takano, Y; Yano, T | 1 |
| Dahiya, R; Hirata, H; Kawamoto, K; Kikuno, N; Nakagawa, M; Tanaka, Y | 1 |
| Cho, M; Grabmaier, K; Hiasa, Y; Hirao, Y; Kitahori, Y; Nakagawa, Y; Ohnishi, T; Ooesterwijk, E; Uemura, H; Yoshikawa, K | 1 |
| Angeloni, D; Braga, E; Dreijerink, K; Duh, FM; Geil, L; Kashuba, V; Klein, G; Kuzmin, I; Lerman, MI; Li, J; Minna, JD; Protopopov, A; Stanbridge, EJ; Zabarovsky, ER; Zbar, B | 1 |
| Dahiya, R; Franks, J; Ishii, N; Li, LC; Nakajima, K; Nojima, D; Ribeiro-Filho, L | 1 |
1 trial(s) available for azacitidine and Adenocarcinoma Of Kidney
| Article | Year |
|---|---|
Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinoma, Renal Cell; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Fetal Hemoglobin; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Injections, Intravenous; Injections, Subcutaneous; Interleukin-2; Kidney Neoplasms; Leukocytes, Mononuclear; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Predictive Value of Tests; Treatment Outcome | 2006 |
46 other study(ies) available for azacitidine and Adenocarcinoma Of Kidney
| Article | Year |
|---|---|
Ginsenoside Rg3 inhibits renal cell carcinoma cell migration, invasion, colony formation, and tube formation and enhances apoptosis through promoting the DNA demethylation and histone acetylation.
Topics: Acetylation; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; DNA Demethylation; DNA Methylation; Histone Deacetylases; Histones; Humans; Kidney Neoplasms; Tumor Suppressor Protein p53 | 2023 |
PON1 hypermethylation is associated with progression of renal cell carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aryldialkylphosphatase; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Databases, Genetic; Disease Progression; DNA Methylation; Drug Resistance, Neoplasm; Epigenesis, Genetic; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Kidney Neoplasms; Mice; Mice, Nude; Sunitinib; Transplantation, Heterologous | 2019 |
Moving beyond hydroxychloroquine: the novel lysosomal autophagy inhibitor ROC-325 shows significant potential in preclinical studies.
Topics: Animals; Antineoplastic Agents; Autophagy; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Hydroxychloroquine; Kidney Neoplasms; Leukemia, Myeloid, Acute; Lysosomes; Mice | 2019 |
Combined Treatment with Valproic Acid and 5-Aza-2'-Deoxycytidine Synergistically Inhibits Human Clear Cell Renal Cell Carcinoma Growth and Migration.
Topics: Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; Drug Synergism; G1 Phase; Humans; Kidney Neoplasms; Valproic Acid | 2018 |
Epigenetic regulation of microRNA expression in renal cell carcinoma.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Kidney Neoplasms; MicroRNAs; Promoter Regions, Genetic; RNA; Vorinostat | 2013 |
CpG dinucleotide-specific hypermethylation of the TNS3 gene promoter in human renal cell carcinoma.
Topics: Azacitidine; Base Pairing; Base Sequence; Carcinoma, Renal Cell; Case-Control Studies; Computational Biology; CpG Islands; DNA Methylation; Exons; HEK293 Cells; Humans; Kidney Neoplasms; Microfilament Proteins; Molecular Sequence Data; Promoter Regions, Genetic; Reproducibility of Results; Sequence Analysis, DNA; Tensins | 2013 |
DNA methyltransferase inhibitor-mediated apoptosis in the Wnt/β-catenin signal pathway in a renal cell carcinoma cell line.
Topics: Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Fragmentation; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Glycoproteins; Humans; Intracellular Signaling Peptides and Proteins; Wnt Signaling Pathway | 2013 |
Reduced expression of Slit2 in renal cell carcinoma.
Topics: Aged; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HEK293 Cells; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Jurkat Cells; Kidney Neoplasms; Male; Middle Aged; Nerve Tissue Proteins | 2014 |
Epigenetic silencing of Na,K-ATPase β 1 subunit gene ATP1B1 by methylation in clear cell renal cell carcinoma.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Humans; Kidney Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Von Hippel-Lindau Tumor Suppressor Protein | 2014 |
Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; HSP27 Heat-Shock Proteins; Humans; Kidney Neoplasms; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
Interferon regulatory factor 8 functions as a tumor suppressor in renal cell carcinoma and its promoter methylation is associated with patient poor prognosis.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Down-Regulation; Female; G2 Phase Cell Cycle Checkpoints; Genes, Tumor Suppressor; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Interferon Regulatory Factors; Kidney Neoplasms; M Phase Cell Cycle Checkpoints; Male; Prognosis; Promoter Regions, Genetic | 2014 |
Methylation‑associated inactivation of LATS1 and its effect on demethylation or overexpression on YAP and cell biological function in human renal cell carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Proliferation; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Phosphoproteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA, Messenger; Signal Transduction; Transcription Factors; Tumor Suppressor Proteins; YAP-Signaling Proteins | 2014 |
Hypermethylation of the 16q23.1 tumor suppressor gene ADAMTS18 in clear cell renal cell carcinoma.
Topics: ADAM Proteins; ADAMTS Proteins; Adult; Aged; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Chromosomes, Human, Pair 16; CpG Islands; Decitabine; Disease-Free Survival; DNA Methylation; Down-Regulation; HEK293 Cells; Humans; Male; Middle Aged; Sequence Analysis, DNA | 2015 |
Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.
Topics: Aged; Azacitidine; Calcium-Binding Proteins; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; CpG Islands; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Male; Middle Aged; Nerve Tissue Proteins; Promoter Regions, Genetic | 2015 |
Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways.
Topics: Aged; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Bone Morphogenetic Protein 2; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, cdc; Humans; Kidney Neoplasms; Kidney Tubules; Male; Middle Aged; Neoplasm Proteins; Nephrectomy; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Transfection; Treatment Outcome | 2015 |
Demethylation of miR-10b plays a suppressive role in ccRCC cells.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; MicroRNAs; Neoplasm Invasiveness; Nuclear Proteins; Phenylbutyrates; Promoter Regions, Genetic; Time Factors; Transfection; Twist-Related Protein 1 | 2015 |
Decitabine induces G2/M cell cycle arrest by suppressing p38/NF-κB signaling in human renal clear cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Carrier Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Decitabine; Dose-Response Relationship, Drug; Down-Regulation; G2 Phase Cell Cycle Checkpoints; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Membrane Proteins; NF-kappa B; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Ubiquitin Thiolesterase | 2015 |
The epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation.
Topics: Adult; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Transformed; Cell Line, Tumor; CpG Islands; DNA Helicases; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Kidney Neoplasms; Nerve Tissue Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Proteins | 2016 |
Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Renal Cell; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kelch-Like ECH-Associated Protein 1; Kidney Neoplasms; Male; Middle Aged; NF-E2-Related Factor 2; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Survival Analysis | 2017 |
Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways.
Topics: Adult; Aged; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Cycle; Chromatin Immunoprecipitation; Decitabine; Disease Progression; Female; Gene Silencing; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Male; Middle Aged; Wnt Proteins | 2009 |
Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Proliferation; Connexins; Decitabine; Deoxycytidine; Down-Regulation; Enzyme Activation; Gap Junction beta-1 Protein; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Kidney Neoplasms; Signal Transduction; Transcriptional Activation; Up-Regulation; Vinblastine | 2010 |
Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Caspase 3; Cell Proliferation; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Intercellular Signaling Peptides and Proteins; Kidney Neoplasms; Male; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Wnt Proteins | 2011 |
Functional and epigenetic characterization of the KRT19 gene in renal cell neoplasms.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Keratin-19; Kidney; Kidney Neoplasms; Male; Middle Aged; Promoter Regions, Genetic | 2011 |
Noncytotoxic differentiation treatment of renal cell cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Carcinoma, Renal Cell; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cellular Senescence; Cytotoxins; Decitabine; DNA Damage; Humans; Kidney Neoplasms; Mice; Mice, Nude; Xenograft Model Antitumor Assays | 2011 |
A demethylating agent enhances chemosensitivity to vinblastine in a xenograft model of renal cell carcinoma.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Decitabine; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Promoter Regions, Genetic; Proteomics; Vinblastine; Xenograft Model Antitumor Assays | 2011 |
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Cadherins; Carcinoma, Renal Cell; Case-Control Studies; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Male; Middle Aged; Promoter Regions, Genetic; Prostatic Neoplasms; ROC Curve; Sensitivity and Specificity; Urinary Bladder Neoplasms | 2011 |
5-aza-2'-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel by decreasing LEF1/phospho-β-catenin expression.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; beta Catenin; Blotting, Western; Carcinoma, Renal Cell; Decitabine; Drug Synergism; Humans; Immunohistochemistry; Kidney Neoplasms; Lymphoid Enhancer-Binding Factor 1; Mice; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection; Xenograft Model Antitumor Assays | 2011 |
Rap1GAP regulates renal cell carcinoma invasion.
Topics: Azacitidine; Cadherins; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Humans; Integrins; Kidney Neoplasms; Neoplasm Invasiveness; Promoter Regions, Genetic; RNA, Small Interfering; Transfection | 2012 |
Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Breast Neoplasms; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Decitabine; Depsipeptides; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; Histone Deacetylase Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Kidney Neoplasms; Methyltransferases; Recombinant Proteins; Tumor Suppressor Proteins | 2012 |
Gene expression profiling of the synergy of 5-aza-2'-deoxycytidine and paclitaxel against renal cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Blotting, Western; Carcinoma, Renal Cell; Decitabine; Drug Synergism; Gene Expression Profiling; Humans; Kidney Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2012 |
Alterations of the WNT7A gene in clear cell renal cell carcinomas.
Topics: Adult; Aged; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Genetic Markers; Humans; Loss of Heterozygosity; Male; Microsatellite Repeats; Middle Aged; Wnt Proteins; Young Adult | 2012 |
5-aza-2'-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: immunotherapeutic implications.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Decitabine; Electrophoresis, Polyacrylamide Gel; Eye Proteins; Humans; Immunotherapy; Kidney Neoplasms; Melanoma-Specific Antigens; Membrane Proteins; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Precipitin Tests; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 2002 |
DNA mismatch repair genes in renal cell carcinoma.
Topics: Azacitidine; Base Pair Mismatch; Blotting, Western; Carcinoma, Renal Cell; Decitabine; DNA Modification Methylases; DNA Repair; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunohistochemistry; Kidney Neoplasms; Male; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2003 |
Restoration of expression of transforming growth factor-beta type II receptor in murine renal cell carcinoma (renca) cells by 5-Aza-2'-deoxycytidine.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Kidney Neoplasms; Mice; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Methylation of the gamma-catenin gene is associated with poor prognosis of renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Renal Cell; CpG Islands; Cytoskeletal Proteins; Decitabine; Desmoplakins; Disease Progression; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Female; gamma Catenin; Humans; Kidney; Kidney Neoplasms; Male; Middle Aged; Mutation; Prognosis; Promoter Regions, Genetic; Survival Rate | 2005 |
Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines.
Topics: Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma; Carcinoma, Renal Cell; Colonic Neoplasms; Decitabine; DNA Methylation; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Isoenzymes; Kidney Neoplasms; Promoter Regions, Genetic; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2005 |
Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Loss of Heterozygosity; Male; Membrane Proteins; Middle Aged; Mitochondrial Proteins; RNA, Messenger; Transfection; Tumor Suppressor Proteins | 2006 |
Identification of novel target genes by an epigenetic reactivation screen of renal cancer.
Topics: Adult; Aged; Azacitidine; Base Sequence; Carcinoma, Renal Cell; Cell Line, Tumor; Collagen Type I; Collagen Type I, alpha 1 Chain; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hydroxamic Acids; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Kidney Neoplasms; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Up-Regulation | 2006 |
Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Interferon-alpha; Interferon-beta; Interferons; Intracellular Signaling Peptides and Proteins; Kidney Neoplasms; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Proteins; Polymerase Chain Reaction; Transplantation, Heterologous; Up-Regulation | 2006 |
Aberrant promoter methylation of the ABCG2 gene in renal carcinoma.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Azacitidine; Base Sequence; Carcinoma, Renal Cell; Cell Line, Tumor; CpG Islands; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Histones; Humans; Kidney Neoplasms; Lysine; Neoplasm Proteins; Promoter Regions, Genetic; Protein Binding; Transcription, Genetic; Von Hippel-Lindau Tumor Suppressor Protein | 2006 |
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cells, Cultured; Cytidine; Death-Associated Protein Kinases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Kidney; Kidney Neoplasms; Male; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms | 2006 |
5-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Renal Cell; Cell Line, Tumor; Connexins; Decitabine; Female; Gap Junction beta-1 Protein; Humans; Mice; Mice, Nude; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Up-Regulation; Xenograft Model Antitumor Assays | 2008 |
DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Immunoprecipitation; Kidney Neoplasms; Membrane Proteins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Wnt Proteins | 2008 |
Activation of the MN/CA9 gene is associated with hypomethylation in human renal cell carcinoma cell lines.
Topics: Antigens, Neoplasm; Azacitidine; Base Sequence; Carcinoma, Renal Cell; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Molecular Sequence Data; Tumor Cells, Cultured | 2000 |
The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis.
Topics: Azacitidine; Carcinoma, Renal Cell; Cell Adhesion; Cell Division; Chromosome Mapping; Chromosomes, Human, Pair 3; DNA Methylation; DNA Primers; DNA, Neoplasm; Doxycycline; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Kidney Neoplasms; Neoplasm Proteins; Promoter Regions, Genetic; Recombinant Proteins; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
CpG methylation of promoter region inactivates E-cadherin gene in renal cell carcinoma.
Topics: Azacitidine; Cadherins; Carcinoma, Renal Cell; Cells, Cultured; CpG Islands; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Enzyme Inhibitors; Gene Silencing; Humans; Immunoenzyme Techniques; Kidney Neoplasms; Neoplasm Staging; Polymerase Chain Reaction; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Transcription, Genetic | 2001 |