azacitidine has been researched along with Adenocarcinoma, Basal Cell in 127 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (4.72) | 18.7374 |
1990's | 16 (12.60) | 18.2507 |
2000's | 61 (48.03) | 29.6817 |
2010's | 41 (32.28) | 24.3611 |
2020's | 3 (2.36) | 2.80 |
Authors | Studies |
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Ahuja, N; Azad, NS; Baretti, M; Cope, L; Durham, JN; Heumann, TR; Leatherman, J; Linden, S; Lopez-Vidal, TY; Monga, DK; O'Dwyer, PJ; Reiss, KA; Sharma, A; Sugar, EA; Weekes, CD | 1 |
Borlak, J; Liu, L; Tang, Z | 1 |
Hosseinpourfeizi, MA; Moaddab, Y; Rezaei, S; Safaralizadeh, R | 1 |
Deng, X; Hou, C; Liang, T; Wang, H; Zhu, L | 1 |
Gabius, HJ; Gebert, J; Katzenmaier, EM; Kloor, M; Kopitz, J | 1 |
Ambs, S; Calin, GA; Croce, CM; Esposito, D; Hudson, RS; Liu, CG; Prueitt, RL; Schetter, AJ; Stephens, RM; Van Roosbroeck, K; Volfovsky, N; Volinia, S; Yi, M | 1 |
Arneth, BM; Fuessel, S; Hagelgans, A; Menschikowski, M; Nacke, B; Siegert, G; Wirth, MP | 1 |
Arai, E; Betsuyaku, T; Kanai, Y; Kohno, T; Sato, T; Soejima, K; Tsuta, K; Watanabe, S | 1 |
Peek, RM; Schneider, BG | 1 |
Mori, A; Niwa, T; Tatematsu, M; Toyoda, T; Tsukamoto, T; Ushijima, T | 1 |
Cheng, Y; Dong, M; Fan, X; Feng, X; Jin, Z; Meltzer, SJ; Mori, Y; Wang, L; Zhang, X; Zhao, Z | 1 |
Cao, Z; Chen, S; Cheng, Y; Dong, M; Fan, X; Feng, X; Gao, Y; Jin, Z; Liu, J; Meltzer, SJ; Mori, Y; Wang, L; Yu, H; Zhang, X; Zhang, Y; Zhao, Z | 1 |
Cui, W; Huang, HQ; Li, N; Zhang, GS | 1 |
Berdel, WE; Dugas, M; Haase, AK; Hascher, A; Hebestreit, K; Jungen, D; Klein, HU; Müller-Tidow, C; Ogawa, S; Rius, M; Rohde, C; Schulze, I; Stoll, M; Thoennissen, NH; Tickenbrock, L; Wiewrodt, R; Witten, A | 1 |
Cheng, Y; Dang, C; Diao, D; Guo, Q; Liu, D; Song, Y; Wang, W; Wu, X; Xia, P; Zhang, H | 1 |
Baylin, SS; Belinsky, SA; Liu, Y; Tellez, CS; Tessema, M; Van Neste, L; Yingling, CM | 1 |
Chen, H; Chu, Y; Dowdy, SC; Jiang, SW; Li, J; Liu, F; Wang, Y; Xiong, Y; Zhang, G; Zhang, R | 1 |
Chen, L; Huang, G; Ren, J; Song, H; Wang, R | 1 |
Cao, Z; Chen, S; Cheng, Y; Dong, M; Fan, X; Feng, X; Gao, Y; Jin, Z; Liu, J; Meltzer, SJ; Mori, Y; Wang, L; Wu, W; Yu, H; Zhang, X; Zhao, Z | 1 |
Aguila, B; Duan, W; Gao, L; Kalvala, A; Otterson, GA; Reese, T; Villalona-Calero, MA | 1 |
Ahrens, TD; Boerries, M; Busch, H; Follo, M; Hembach, S; Hoeppner, J; Hopt, UT; Lassmann, S; Ostendorp, J; Timme, S; Werner, M | 1 |
Choi, JH; Kim, GJ; Kim, HS; Kim, J; Kim, N; Lee, HJ; Lee, JO; Lee, SK; Lee, YW; Moon, JW; Park, SH; Seo, JS | 1 |
Dong, Y; Ji, T; Liang, J; Ma, Z; Xiao, Y; Yin, G | 1 |
Gao, B; Li, GH; Shao, GG; Yang, B; Yang, ZG | 1 |
Chen, J; Gao, J; Gu, X; Liu, T; Lü, L; Mei, Z; Zeng, H | 1 |
Du, Z; Feng, X; Lai, Q; Li, A; Liu, B; Song, J; Sun, X; Wang, H; Xu, Y | 1 |
Akizuki, R; Endo, S; Hichino, A; Ikari, A; Matsunaga, T; Okamoto, M; Taga, S | 1 |
Califano, JA; Henrique, R; Jeronimo, C; Kim, MS; Lee, J; Liu, JW; Moon, CS; Nagpal, JK; Ostrow, KL; Sidransky, D; Sun, W; Trink, B; Van Criekinge, W; Zhou, S | 1 |
Chen, H; El-Rifai, W; Peng, DF; Razvi, M; Roessner, A; Schneider-Stock, R; Washington, K | 1 |
Abraham, JM; Agarwal, R; Beer, DG; Cheng, Y; David, S; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Mori, Y; Olaru, A; Paun, B; Sato, F; Selaru, FM; Shimada, Y; Yang, J | 1 |
Albertus, DL; Beer, DG; Bigbee, WL; Chang, AC; Chen, G; Chinnaiyan, AM; Giordano, TJ; Hartojo, W; Lin, L; Orringer, MB; Seder, CW; Silvers, A; Thomas, DG; Wang, X | 1 |
Hou, K; Hu, X; Jing, W; Liu, Y; Qu, X; Teng, Y; Yang, X; Zhang, J; Zhang, Y | 1 |
Foster, BA; Karpf, AR; Mavis, CK; Morey Kinney, SR | 1 |
Billam, M; Davidson, NE; Sobolewski, MD | 1 |
Chen, Y; Collins, C; Huo, D; Nwachukwu, C; Olopade, OI; Rowell, J; Slamon, DJ; Xu, J | 1 |
Akashi, H; Igarashi, S; Imai, K; Issa, JP; Itoh, F; Kai, M; Maruyama, R; Nojima, M; Sasaki, Y; Shen, L; Shinomura, Y; Sugai, T; Suzuki, H; Tokino, T; Toyota, M; Watanabe, Y; Yamamoto, E; Yamamoto, H | 1 |
Costanzo, C; Dandrea, M; Donadelli, M; Palmieri, M; Scarpa, A | 1 |
Gutkin, DW; Shurin, GV; Shurin, MR; Song, EY; Tourkova, IL | 1 |
Ishii, J; Kashiwagi, K; Kitamura, H; Masuda, M; Mitsui, H; Ogura, T; Ohmori, T; Okudela, K; Oshiro, H; Sakaeda, M; Sato, H; Shimoyamada, H; Suzuki, T; Tajiri, M; Woo, T; Yazawa, T | 1 |
El-Rifai, W; Hu, T; Jackson, K; Marshal, D; Peng, D; Soutto, M | 1 |
Adachi, Y; Hizaki, K; Imai, K; Kato, N; Nakazawa, M; Sanchez, JV; Sasaki, S; Shinomura, Y; Sukawa, Y; Suzuki, H; Taniguchi, H; Tanuma, T; Yamamoto, H | 1 |
Al-Sohaily, S; Cooper, WA; Kennedy, CW; Kohonen-Corish, MR; McCaughan, BC; Mladenova, DN; Pangon, L; Selinger, CI; Stirzaker, C | 1 |
Chen, HM; Du, W; Fang, JY; Hong, J; Tang, JT; Wang, JL; Wang, YC; Xiong, H; Zhao, SL | 1 |
El-Rifai, W; Hu, TL; Jiang, A; Moskaluk, CA; Peng, D; Schneider-Stock, R; Washington, MK | 1 |
Cronk, RJ; Lang, JM; McNeel, DG; Smith, HA | 1 |
Akahira, J; Hiroki, E; Ito, K; Miki, Y; Nagase, S; Sasano, H; Sugawara, J; Suzuki, F; Suzuki, T; Yaegashi, N | 1 |
Chang, YL; Hong, TM; Jou, YS; Lin, JC; Lin, TC; Wu, CT; Wu, JY; Wu, YY; Yang, PC | 1 |
Cogdill, AP; Cooper, ZA; Ferrone, CR; Fiedler, A; Frederick, DT; Garber, HR; Rosenberg, L; Thayer, SP; Wargo, JA; Warshaw, AL | 1 |
Cornfield, DB | 1 |
Aoki, D; Banno, K; Kisu, I; Kobayashi, Y; Masuda, K; Nomura, H; Susumu, N; Tominaga, E; Tsuji, K; Ueki, A; Yamagami, W; Yanokura, M | 1 |
Jiang, GY; Li, QC; Wang, EH; Xu, HT; Xu, K; Yang, LH; Zhang, XP; Zhao, HY | 1 |
Fukuyama, Y; Gazdar, AF; Minna, JD; Tockman, MS; Toyooka, S; Wistuba, II | 1 |
Chen, Z; Cheng, X; Wu, Y; Zhu, B | 1 |
Deng, G; Han, SW; Ho, JJ; Kim, YS; Kuan, SF; Pan, PL | 1 |
Goggins, M; Maehara, N; Sato, N; Su, GH | 1 |
Durkin, ME; Popescu, NC; Yuan, BZ | 1 |
Chan, AW; Chan, MW; Chan, PK; Lee, TL; Lo, KW; To, KF; Tong, JH; Yu, MY | 1 |
Brune, K; Fukushima, N; Goggins, M; Hruban, RH; Matsubayashi, H; Sahin, F; Sato, N; Walter, KM; Yeo, CJ | 1 |
Borczuk, AC; Brody, JS; Busch, S; Capurro, M; D'Armiento, JM; Filmus, J; Kim, H; Lange, J; Powell, CA; Rothman, PB; Xu, GL | 1 |
Casey, G; Issa, JP; Kasturi, L; Li, H; Lutterbaugh, J; Markowitz, SD; Myeroff, L; Plass, C; Pretlow, TP; Rerko, RM; Romero, MF; Smiraglia, D; Willis, J; Willson, JK | 1 |
Chan, AS; Chan, TL; Chen, X; Chu, KM; Leung, SY; Li, R; So, S; Tsui, WY; Yuen, ST | 1 |
Chow, BK; Lee, LT; Ng, SS; Pang, RT; Yung, WH | 1 |
Honoki, K; Mii, Y; Mori, T; Takakura, Y; Tsujiuchi, T; Tsutsumi, M; Yoshitani, K | 1 |
Alder, H; Aqeilan, RI; Cesari, R; Croce, CM; Kanematsu, T; Kuroki, T; Matsuyama, A; Mori, M; Nolli, ML; Rattan, S; Trapasso, F; Williams, NN; Yendamuri, S | 1 |
Logsdon, CD; Okami, J; Simeone, DM | 1 |
Eshleman, JR; Fukushima, N; Goggins, M; Iacobuzio-Donahue, CA; Miyagi, Y; Parker, AR; Sato, N | 1 |
Chen, J; Ebert, MP; Götze, T; Klein-Hitpass, L; Leodolter, A; Malfertheiner, P; Röcken, C | 1 |
Furukawa, T; Horii, A; Kanai, N; Sunamura, M; Xu, S | 1 |
Abe, T; Chang, R; Dhara, S; Goggins, M; Hustinx, SR; Maitra, A; Martin, ST; Sato, N | 1 |
Dowdy, SC; Eberhardt, NL; Gonzalez Bosquet, J; Jiang, SW; Podratz, KC; Xiong, Y; Zhao, Y | 1 |
Aung, PP; Kawahara, K; Kuraoka, K; Nakayama, H; Noguchi, T; Oue, N; Shutoh, M; Yasui, W | 1 |
Benhattar, J; Bosman, FT; Braunschweig, R; Clément, G; Pasquier, N | 1 |
Bae, HI; Kim, DS; Kim, MJ; Kim, SG; Lee, JY; Lee, YM; Park, JY | 1 |
Hu, L; Huang, G; Sun, D; Tang, A; Van, do N; Zhang, Z | 1 |
Carvalho, AL; Cerveira, N; Costa, VL; Henrique, R; Hoque, MO; Jerónimo, C; Oliveira, J; Ribeiro, FR; Sidransky, D; Teixeira, MR | 1 |
Fields, CR; Pan, YX; Robertson, KD; Su, N; Zhong, S | 1 |
Abraham, JM; Cheng, Y; Greenwald, BD; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Mori, Y; Paun, BC; Sato, F; Wang, S; Yang, J | 1 |
Euhus, DM; Fong, KM; Gao, B; Gazdar, AF; Gerald, W; Girard, L; Jiang, A; Kim, YH; Lam, CL; Lewis, CM; Minna, JD; Nanda, R; Olopade, OI; Perou, CM; Pollack, JR; Sato, M; Shames, DS; Shay, JW; Shivapurkar, N; Shyr, Y; Wong, M | 1 |
Fujisawa, T; Gazdar, AF; Iizasa, T; Minna, JD; Shames, DS; Shigematsu, H; Shivapurkar, N; Sunaga, N; Suzuki, M; Takahashi, T | 1 |
Chen, Y; Deutschmann, N; Knösel, T; Kotb, WF; Lund, P; Pacyna-Gengelbach, M; Petersen, I; Schlüns, K; Sers, C; Usui, T; Yasumoto, H; Ye, F | 1 |
Beckhove, P; Buchler, MW; Galindo-Escobedo, LV; Geng, W; Koch, M; Krempien, R; Niethammer, AG; Rimoldi, D; Romero, P; Schmitz-Winnenthal, FH; Weitz, J; Z'graggen, K | 1 |
Day, ML; Gschwend, JE; Kuefer, R; McCabe, MT; Wojno, KJ; Zorn, CS | 1 |
Chen, D; Cheng, L; Gao, L; Lu, ZH; Pan, SY; Shu, YQ; Xie, EF; Yang, D; Zhang, JN; Zhang, LX | 1 |
Bang, YJ; Im, SA; Jong, HS; Jung, Y; Kim, TY; Park, J; Park, JH; Robertson, KD | 1 |
Ekström, L; Gustafsson, O; Morfin, R; Olsson, M; Rane, A; Rietz, BD; Skogastierna, C; Tolf, A | 1 |
Dacic, S; Guo, M; Landreneau, R; Siegfried, JM; Sun, Q; Yu, J; Yue, W; Zhang, L; Zhou, W | 1 |
Akiyoshi, J; Aoki, D; Banno, K; Fujii, T; Hirasawa, A; Iwata, T; Kawaguchi, M; Kobayashi, Y; Kuwabara, Y; Susumu, N; Tsukazaki, K; Yanokura, M | 1 |
Chan, FK; Cheng, YY; Jin, VX; Leung, WK; Li, J; Man, EP; Sung, JJ; Tao, Q; To, KF; Wong, YP; Yu, J | 1 |
Luo, J; Qi, J; Tao, WH; Zhu, YQ | 1 |
Chung, DC; Kawasaki, T; Kirley, SD; Kwon, E; Lauwers, GY; Mino-Kenudson, M; Ogino, S; Park, DY; Rueda, BR; Sakamoto, H; Zukerberg, LR | 1 |
Hosoya, K; McDonell, N; Niwa, T; Shirai, T; Takahashi, S; Tsujino, Y; Ushijima, T; Watanabe, N; Yamashita, S | 1 |
Luo, J; Qi, J; Tao, WH; Zhang, JM; Zhu, YQ | 1 |
Fitzgerald, RC; Gjerset, RA; Huang, Y; Peters, CJ | 1 |
Chahinian, AP; Greenfield, DS; Holland, JF; Ohnuma, T | 1 |
Bianco, AR; Caraglia, M; Correale, P; Genua, G; Leardi, A; Pepe, S; Pinto, A; Tagliaferri, P; Zagonel, V | 1 |
Blessing, JA; Look, KY; Manetta, A | 1 |
Parekh, HK; Simpkins, H | 1 |
Ben-Baruch, N; Cowan, KH; Denicoff, AM; Goldspiel, BR; O'Shaughnessy, JA | 1 |
Côté, S; Momparler, RL | 2 |
Bang, YJ; Choe, KJ; Jung, CW; Kang, SH; Kim, BK; Kim, NK; Koeffler, HP; Lee, KU; Lee, YY; Seo, JY | 1 |
el Yaagoubi, M; Khalid, A; Siest, G; Visvikis, A; Wellman, M | 1 |
Chi, SG; deVere White, RW; Gumerlock, PH; Muenzer, JT | 1 |
Côté, S; Momparler, RL; Sinnett, D | 1 |
Concha, A; Garrido, F; Hortas, ML; Morell, M; Redondo, M; Ruiz-Cabello, F; Serrano, A | 1 |
Nakamura, N; Takenaga, K | 1 |
Byun, DS; Chi, SG; Kang, MJ; Kim, HJ; Park, BJ; Park, JH; Park, JI | 1 |
Bang, YJ; Choi, HH; Jong, HS; Kang, SH; Kim, NK; Kim, WH; Ryu, MH; Song, SH | 1 |
Arapshian, A; Kuppumbatti, YS; Mira-y-Lopez, R | 1 |
Anna, CH; Barrett, JC; Devereux, TR; Foley, JF; Patel, AC; Stockton, PS; Tyson, FL | 1 |
Imai, K; Itoh, F; Kakiuchi, H; Kikuchi, T; Suzuki, H; Toyota, M | 1 |
Ammanamanchi, S; Brattain, MG; Periyasamy, S; Tillekeratne, MP | 1 |
Chen, GA; Fischette, MR; Guo, ZS; Hong, JA; Nguyen, DM; Ohnmacht, GA; Schrump, DS; Weiser, TS | 1 |
Akakura, K; Ichikawa, T; Igarashi, T; Ito, H; Kito, H; Nakayama, T; Sekita, N; Shiraishi, T; Suzuki, H; Toyota, M; Watanabe, M; Yoshie, O | 1 |
Ashida, T; Fujiki, T; Fujiya, M; Honda, M; Kohgo, Y; Saitoh, Y; Tanabe, H; Watari, J | 1 |
Chen, A; Deng, G; Kim, YS; Pong, E | 1 |
Arnold, JM; Chenevix-Trench, G; Cummings, M; Purdie, D | 1 |
Goggins, M; Hruban, RH; Issa, JP; Skinner, H; Toyota, M; Ueki, T; Walter, KM; Yeo, CJ | 1 |
Abbruzzese, JL; Anzai, H; Frost, P | 1 |
Elliott, MS; Gündüz, U; Houghton, JA; Houghton, PJ; Katze, JR; Seubert, PH; Trewyn, RW | 1 |
Casper, ES; Kelsen, DP; Schwartz, GK | 1 |
Brissette, L; Deeley, RG; Elliott, BE; Holden, JJ; Marshall, J; Mudrik, K; Vekemans, M; Xu, W | 1 |
Arundel, CM; Leith, JT | 1 |
Azuma, M; Hayashi, Y; Sato, M; Yanagawa, T; Yoshida, H; Yura, Y | 1 |
Arnold, M; Bosman, P; Carlow, DA; Elliott, BE; Hampton, N; Ivimey, L | 1 |
Abele, R; Bruntsch, U; Clavel, M; Dodion, P; Gundersen, S; Pinedo, HM; Renard, J; Smyth, J; van Glabbeke, M | 1 |
Hahn, RG; Moertel, CG; Reitemeier, RJ; Schutt, AJ | 1 |
8 trial(s) available for azacitidine and Adenocarcinoma, Basal Cell
Article | Year |
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A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; DNA Methylation; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Pancreatic Neoplasms | 2022 |
MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Blotting, Western; Cell Movement; Cell Proliferation; Chromatin Immunoprecipitation; Colorectal Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA Primers; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Immunoenzyme Techniques; Luciferases; Lymphatic Metastasis; Male; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Prognosis; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2011 |
Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Non-Small-Cell Lung; CpG Islands; DNA Methylation; DNA Mutational Analysis; DNA, Neoplasm; Down-Regulation; Epigenesis, Genetic; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunoenzyme Techniques; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Membrane Proteins; Nerve Tissue Proteins; Promoter Regions, Genetic; Receptor Activity-Modifying Protein 2; Receptor Activity-Modifying Proteins; Receptors, Immunologic; Roundabout Proteins; Tumor Cells, Cultured | 2007 |
A phase II study of fazarabine in patients with advanced ovarian cancer. A Gynecologic Oncology Group study.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Female; Humans; Infusions, Intravenous; Neoplasm Recurrence, Local; Ovarian Neoplasms; Treatment Outcome | 1995 |
Phase II study of fazarabine (NSC 281272) in patients with metastatic colon cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Azacitidine; Colonic Neoplasms; Drugs, Investigational; Female; Humans; Infusions, Intravenous; Male; Middle Aged | 1993 |
Phase II trial of fazarabine (arabinofuranosyl-5-azacytidine) in patients with advanced pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Azacitidine; Female; Humans; Infusion Pumps; Male; Middle Aged; Pancreatic Neoplasms | 1992 |
The EORTC Early Clinical Trials Cooperative Group experience with 5-aza-2'-deoxycytidine (NSC 127716) in patients with colo-rectal, head and neck, renal carcinomas and malignant melanomas.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Clinical Trials as Topic; Decitabine; Female; Hematologic Diseases; Humans; Male; Melanoma; Middle Aged; Neoplasms | 1987 |
Phase II study of 5-azacytidine (NSC-102816) in the treatment of advanced gastrointestinal cancer.
Topics: Adenocarcinoma; Adult; Aged; Azacitidine; Blood Cell Count; Blood Platelets; Clinical Trials as Topic; Cytidine; Female; Gastrointestinal Neoplasms; Humans; Leukocyte Count; Male; Middle Aged; Nausea; Triazines; Vomiting | 1972 |
119 other study(ies) available for azacitidine and Adenocarcinoma, Basal Cell
Article | Year |
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Combined inhibition of histone deacetylase and cytidine deaminase improves epigenetic potency of decitabine in colorectal adenocarcinomas.
Topics: Adenocarcinoma; Azacitidine; Cell Line, Tumor; Colorectal Neoplasms; Cytidine Deaminase; Decitabine; DNA Methylation; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Prospective Studies; Tetrahydrouridine; Tumor Microenvironment; Tumor Suppressor Protein p53 | 2023 |
Contribution of DNA methylation and EZH2 in SRBC down-regulation in gastric cancer.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; DNA Methylation; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Intracellular Signaling Peptides and Proteins; Male; Promoter Regions, Genetic; Pyridones; Stomach Neoplasms | 2020 |
Hypermethylation of WIF1 and its inhibitory role in the tumor growth of endometrial adenocarcinoma.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adult; Aged; Animals; Azacitidine; Cell Line, Tumor; Cell Proliferation; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Down-Regulation; Endometrial Neoplasms; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Mice; Mice, Nude; Middle Aged; Prognosis; Proto-Oncogene Proteins c-myc; Repressor Proteins | 2017 |
Analyzing epigenetic control of galectin expression indicates silencing of galectin-12 by promoter methylation in colorectal cancer.
Topics: Acetylation; Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cohort Studies; Colorectal Neoplasms; Decitabine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Epithelial Cells; Female; Galectins; Histones; Humans; Male; Middle Aged; Neoplasm Staging; Promoter Regions, Genetic; Protein Isoforms | 2017 |
Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer.
Topics: Adenocarcinoma; Aged; Azacitidine; Case-Control Studies; Cell Line, Tumor; Conserved Sequence; Decitabine; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation, Neoplastic; Genome, Human; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Metribolone; Middle Aged; Oligonucleotide Array Sequence Analysis; Prostate; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; RNA, Untranslated; Testosterone Congeners; Transcriptome | 2013 |
Deregulated expression of urokinase and its inhibitor type 1 in prostate cancer cells: role of epigenetic mechanisms.
Topics: Adenocarcinoma; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; DNA, Neoplasm; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Neoplasm Invasiveness; Plasminogen Activator Inhibitor 1; Prostate; Prostatic Neoplasms; Urokinase-Type Plasminogen Activator | 2013 |
DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Azacitidine; DNA Methylation; DNA Probes; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Neoplasm; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Precancerous Conditions; Proportional Hazards Models; RNA, Messenger | 2013 |
Gastric cancer prevention by demethylation.
Topics: Adenocarcinoma; Animals; Azacitidine; Decitabine; DNA-Cytosine Methylases; Helicobacter Infections; Helicobacter pylori; Male; Stomach Neoplasms | 2013 |
Prevention of Helicobacter pylori-induced gastric cancers in gerbils by a DNA demethylating agent.
Topics: Adenocarcinoma; Animals; Azacitidine; Carcinogens; Decitabine; Disease Models, Animal; DNA Methylation; DNA-Cytosine Methylases; Drug Evaluation, Preclinical; Gene Expression Regulation, Neoplastic; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Methylnitrosourea; Stomach Neoplasms | 2013 |
Endoglin promoter hypermethylation identifies a field defect in human primary esophageal cancer.
Topics: Adenocarcinoma; Aged; Antigens, CD; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Decitabine; DNA Methylation; Endoglin; Esophageal Neoplasms; Esophagus; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Staging; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; ROC Curve; Tumor Cells, Cultured | 2013 |
MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Case-Control Studies; Decitabine; DNA Methylation; Esophageal Neoplasms; Esophagus; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Myelin and Lymphocyte-Associated Proteolipid Proteins; Neoplasm Grading; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; ROC Curve; Tumor Cells, Cultured | 2013 |
Effect of 5- AZn-2 '-deoxycytidine on proliferation of human lung adenocarcinoma cell line A549 in vitro.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cell Shape; Decitabine; Humans; Lung Neoplasms; Malondialdehyde; Superoxide Dismutase | 2013 |
DNA methyltransferase inhibition reverses epigenetically embedded phenotypes in lung cancer preferentially affecting polycomb target genes.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azacitidine; Binding Sites; Cell Line, Tumor; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Phenotype; Polycomb-Group Proteins | 2014 |
Detection of aberrant hypermethylated spastic paraplegia-20 as a potential biomarker and prognostic factor in gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Case-Control Studies; Cell Cycle Proteins; DNA Methylation; Female; Follow-Up Studies; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Polymerase Chain Reaction; Prognosis; Promoter Regions, Genetic; Proteins; Stomach; Stomach Neoplasms; Survival Rate; Tumor Cells, Cultured | 2014 |
Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers.
Topics: Adenocarcinoma; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome-Wide Association Study; Humans; Lung Neoplasms; Promoter Regions, Genetic; Reproducibility of Results; Smoking | 2014 |
Chromatin composition alterations and the critical role of MeCP2 for epigenetic silencing of progesterone receptor-B gene in endometrial cancers.
Topics: Adenocarcinoma; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; DNA-Binding Proteins; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Methyl-CpG-Binding Protein 2; Neoplasm Proteins; Protein Binding; Protein Interaction Mapping; Real-Time Polymerase Chain Reaction; Receptors, Progesterone; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Transcription Factors | 2014 |
Secreted frizzled related protein 1 modulates taxane resistance of human lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Azacitidine; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Male; Membrane Proteins; Mice, Inbred BALB C; Oligonucleotide Array Sequence Analysis; Sulfonamides; Taxoids; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2014 |
Temporal evolution in caveolin 1 methylation levels during human esophageal carcinogenesis.
Topics: Adenocarcinoma; Area Under Curve; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Caveolin 1; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; RNA, Messenger; ROC Curve; Time Factors | 2014 |
Overexpression of Rad51C splice variants in colorectal tumors.
Topics: Adenocarcinoma; Alternative Splicing; Amino Acid Sequence; Azacitidine; Cell Line, Tumor; Colorectal Neoplasms; DNA Methylation; DNA Repair; DNA-Binding Proteins; DNA, Neoplasm; Exons; Fanconi Anemia Complementation Group D2 Protein; Gene Expression Profiling; Humans; Matched-Pair Analysis; Microsatellite Instability; Molecular Sequence Data; Neoplasm Proteins; Promoter Regions, Genetic; Protein Isoforms; Protein Structure, Tertiary; RNA, Messenger; RNA, Neoplasm | 2015 |
Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine.
Topics: Acetylation; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Benzamides; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Survival; Decitabine; Depsipeptides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Pyridines; Transcriptome; Vorinostat | 2015 |
Promoter hypermethylation of membrane type 3 matrix metalloproteinase is associated with cell migration in colorectal adenocarcinoma.
Topics: Adenocarcinoma; Aged; Azacitidine; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Decitabine; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 16; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering | 2015 |
[5-aza-2'-deoxycytidine suppresses the growth of human lung adenocarcinoma cells in nude mouse xenograft models and its effect on methylation status and expression of TFPI-2 gene].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Proliferation; Decitabine; Disease Models, Animal; DNA Methylation; Gene Expression Regulation, Neoplastic; Glycoproteins; Heterografts; Humans; Lung Neoplasms; Mice; Mice, Nude; Random Allocation; RNA, Messenger | 2015 |
5-Aza-CdR can reverse gefitinib resistance caused by DAPK gene promoter methylation in lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Azacitidine; Blotting, Western; Cell Line, Tumor; Death-Associated Protein Kinases; DNA Methylation; Drug Resistance, Neoplasm; Flow Cytometry; Gefitinib; Humans; Lung Neoplasms; Polymerase Chain Reaction; Promoter Regions, Genetic; Quinazolines | 2015 |
Aberrant methylation of microRNA-193b in human Barrett's esophagus and esophageal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Azacitidine; Barrett Esophagus; Biomarkers, Tumor; Cell Line, Tumor; DNA Methylation; Down-Regulation; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Immunohistochemistry; Male; MicroRNAs; Middle Aged; Promoter Regions, Genetic | 2016 |
Hypermethylation of ATP-binding cassette B1 (ABCB1) multidrug resistance 1 (MDR1) is associated with cisplatin resistance in the A549 lung adenocarcinoma cell line.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Azacitidine; Cell Survival; Cisplatin; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; RNA, Messenger | 2016 |
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Azacitidine; Butyric Acid; Cell Proliferation; Chromones; Claudin-2; Down-Regulation; Epigenesis, Genetic; Humans; Hydroxamic Acids; Lung Neoplasms; MicroRNAs; Morpholines; Nitriles; RNA, Messenger; Signal Transduction; Sulfones | 2017 |
ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer.
Topics: Adenocarcinoma; Aged; Azacitidine; Base Sequence; Biomarkers, Tumor; Cell Cycle; Cell Proliferation; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Molecular Sequence Data; Neoplasm Staging; Prostatic Hyperplasia; Prostatic Neoplasms; Tumor Cells, Cultured | 2008 |
DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Barrett Esophagus; Cell Transformation, Neoplastic; CpG Islands; Decitabine; Disease Progression; DNA Methylation; DNA, Neoplasm; Down-Regulation; Epigenesis, Genetic; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Transferase; Humans; Hydroxamic Acids; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 2009 |
Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors.
Topics: Adenocarcinoma; Azacitidine; Base Sequence; Cadherins; Cell Line, Tumor; DNA Methylation; DNA Primers; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors | 2008 |
AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma.
Topics: Acetylation; Adenocarcinoma; Adipokines; Adult; Aged; Aged, 80 and over; Autoantibodies; Azacitidine; Biomarkers, Tumor; Carrier Proteins; Case-Control Studies; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycoproteins; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Lung Neoplasms; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Cells, Cultured | 2008 |
GSTP1 determines cis-platinum cytotoxicity in gastric adenocarcinoma MGC803 cells: regulation by promoter methylation and extracellular regulated kinase signaling.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Azacitidine; Cell Line, Tumor; Cisplatin; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Humans; Inactivation, Metabolic; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Transcription, Genetic | 2009 |
Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Drug Combinations; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Glutathione Transferase; Hydroxamic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Prostate; Prostatic Neoplasms; RNA, Messenger | 2009 |
Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells.
Topics: Adenocarcinoma; Apoptosis Regulatory Proteins; Azacitidine; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytidine; Cytidine Deaminase; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Neoplasm Proteins; Receptors, Estrogen; S Phase; Tumor Stem Cell Assay; Vorinostat | 2010 |
CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.
Topics: Adenocarcinoma; Azacitidine; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Hydroxamic Acids; Neoplasm Proteins; Promoter Regions, Genetic; Protein Binding; RNA, Messenger; Transcription Factors; Transcription, Genetic | 2010 |
IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.
Topics: Adenocarcinoma; Adenoma; Azacitidine; Cell Line, Tumor; Cellular Senescence; Colorectal Neoplasms; Consensus Sequence; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Silencing; Genes, p53; Histones; Humans; Insulin-Like Growth Factor Binding Proteins; Neoplasm Proteins; Phenotype; Proto-Oncogene Proteins B-raf; Recombinant Fusion Proteins; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2010 |
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines.
Topics: Adenocarcinoma; Azacitidine; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA; DNA Methylation; Gene Silencing; Humans; Hydroxamic Acids; Interleukin-6; Methyl-CpG-Binding Protein 2; NF-kappa B; Pancreatic Neoplasms | 2009 |
Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells.
Topics: Adenocarcinoma; Azacitidine; Base Sequence; Cell Line, Tumor; Cell Movement; Chemokines, CXC; Decitabine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Sequence Data; Promoter Regions, Genetic; Prostatic Neoplasms; RNA, Messenger | 2010 |
Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells.
Topics: Adenocarcinoma; Animals; Azacitidine; Cell Line, Tumor; Decitabine; Early Growth Response Protein 1; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; Vascular Endothelial Growth Factor A | 2010 |
Epigenetic silencing of somatostatin in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Methylation; Predictive Value of Tests; Reproducibility of Results; RNA, Messenger; Somatostatin; Stomach Neoplasms | 2011 |
Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Antineoplastic Agents, Alkylating; Azacitidine; Caco-2 Cells; Cell Survival; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Gene Expression; Gene Silencing; Humans; Hydroxamic Acids; Receptors, Calcium-Sensing; RNA, Messenger; Tissue Array Analysis | 2011 |
Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatin Immunoprecipitation; Cohort Studies; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunoenzyme Techniques; Lung Neoplasms; Male; Matrix Attachment Region Binding Proteins; Middle Aged; Neoplasm Staging; Prognosis; Tissue Array Analysis | 2011 |
Location-specific epigenetic regulation of the metallothionein 3 gene in esophageal adenocarcinomas.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; CpG Islands; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Histones; Humans; Lymphatic Metastasis; Metallothionein 3; Middle Aged; Neoplasm Staging; Nerve Tissue Proteins; Promoter Regions, Genetic; Protein Processing, Post-Translational; Repressor Proteins | 2011 |
Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer.
Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Azacitidine; Cancer Vaccines; Cell Line, Tumor; Decitabine; Epitopes; Female; Gene Expression Regulation, Neoplastic; HLA-A2 Antigen; HLA-DR1 Antigen; Humans; Immunotherapy; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Molecular Targeted Therapy; Multigene Family; Neoplasm Metastasis; Neoplasm Proteins; Prostatic Neoplasms; Repressor Proteins; Sequence Alignment; Sequence Homology, Amino Acid; T-Cell Antigen Receptor Specificity | 2011 |
MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma.
Topics: Adenocarcinoma; Apoptosis; Azacitidine; Cell Cycle; Cell Division; Cell Line, Tumor; Decitabine; DNA Methylation; Endometrial Neoplasms; Female; Genes, Tumor Suppressor; Humans; Immunohistochemistry; MicroRNAs; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Proto-Oncogene Mas; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Animals; Antigens, Neoplasm; Azacitidine; Base Sequence; Cell Adhesion Molecules; Cell Line, Tumor; Decitabine; Disease Models, Animal; Epigenesis, Genetic; Female; Gene Expression; Gene Expression Regulation; Gene Silencing; Histocytochemistry; Humans; Immunohistochemistry; Lung Neoplasms; Male; Mice; Middle Aged; Models, Biological; Molecular Sequence Data; Receptor, IGF Type 1; Signal Transduction | 2012 |
Targeting the MAGE A3 antigen in pancreatic cancer.
Topics: Adenocarcinoma; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cytokines; Decitabine; Deoxycytidine; DNA Methylation; Gemcitabine; Humans; Hydroxamic Acids; Immunotherapy; Male; Neoplasm Proteins; Pancreas; Pancreatic Neoplasms; Receptors, Antigen, T-Cell; T-Lymphocytes; Testis; Valproic Acid | 2012 |
Erythroblastic sarcoma, an extremely rare variant of myeloid sarcoma.
Topics: Abnormal Karyotype; Adenocarcinoma; Aged; Azacitidine; Biopsy, Large-Core Needle; Bone Marrow; Bone Marrow Neoplasms; Bone Neoplasms; Combined Modality Therapy; Disease Progression; Drug Therapy, Combination; Erythroblasts; Erythropoietin; Fatal Outcome; Humans; Lymph Nodes; Male; Myelodysplastic Syndromes; Rare Diseases; Rectal Neoplasms; Sarcoma, Myeloid | 2012 |
Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Exodeoxyribonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; RecQ Helicases; RNA, Small Interfering; Topoisomerase I Inhibitors; Uterine Cervical Neoplasms; Werner Syndrome Helicase | 2012 |
Abnormal hypermethylation and clinicopathological significance of Axin gene in lung cancer.
Topics: Adenocarcinoma; Axin Protein; Azacitidine; Base Sequence; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Molecular Sequence Data; Neoplasm Staging; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Azacitidine; Blotting, Western; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 8; CpG Islands; Decitabine; DNA Modification Methylases; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Loss of Heterozygosity; Lung Neoplasms; Nerve Tissue Proteins; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Induction of TRAG-3 expression in A549 lung adenocarcinoma cell line by 5-aza-2' deoxyazacytidine.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lung Neoplasms; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2002 |
Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Azacitidine; Base Sequence; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Mucin 5AC; Mucin-2; Mucins; Neoplasm Invasiveness; Neoplasm Proteins; Pancreas; Pancreatic Neoplasms; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm | 2003 |
Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinases; Methylation; Neoplasm Invasiveness; Pancreatic Neoplasms; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2003 |
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers.
Topics: Adenocarcinoma; Azacitidine; Base Sequence; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; GTPase-Activating Proteins; Humans; Liver Neoplasms; Male; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Promoter Regions, Genetic; Prostatic Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2003 |
Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.
Topics: Adenocarcinoma; Adult; Aged; Azacitidine; Carcinoma, Squamous Cell; Chromosomes, Human, Pair 3; DNA Methylation; DNA Primers; DNA, Neoplasm; DNA, Viral; Enzyme Inhibitors; Female; Gene Silencing; Genes, Tumor Suppressor; Humans; Loss of Heterozygosity; Middle Aged; Mutation; Neoplasm Proteins; Neoplasm Staging; Papillomaviridae; Papillomavirus Infections; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tumor Virus Infections; Uterine Cervical Neoplasms | 2003 |
Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Cyclin D2; Cyclins; Decitabine; Digestive System; DNA Methylation; Female; Humans; Male; Middle Aged; Pancreatic Juice; Pancreatic Neoplasms; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA; Transfection | 2003 |
The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.
Topics: Adenocarcinoma; Animals; Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; Enzyme Inhibitors; Gene Expression Profiling; Genes, Tumor Suppressor; Glypicans; Humans; Hydroxamic Acids; Lung Neoplasms; Membrane Proteins; Mice; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Respiratory Mucosa; Smoking; Tumor Suppressor Proteins | 2003 |
SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers.
Topics: Adenocarcinoma; Adenoma; Azacitidine; Base Sequence; Cation Transport Proteins; Colonic Neoplasms; DNA Methylation; DNA, Neoplasm; Exons; Gene Silencing; Genes, Tumor Suppressor; Humans; Intestinal Mucosa; Ion Transport; Molecular Sequence Data; Monocarboxylic Acid Transporters; Recombinant Fusion Proteins; Sodium; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2003 |
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.
Topics: Adenocarcinoma; Azacitidine; Cell Line; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Helix-Loop-Helix Motifs; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Inhibitor of Differentiation Proteins; Microsatellite Repeats; Promoter Regions, Genetic; Stomach Neoplasms; Transcription Factors | 2003 |
CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene.
Topics: Adenocarcinoma; Animals; Azacitidine; Base Composition; Base Sequence; Cattle; Cells, Cultured; CpG Islands; Cytosine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Drosophila; Enzyme Inhibitors; Gene Expression Regulation; Humans; Molecular Sequence Data; Pancreatic Neoplasms; Promoter Regions, Genetic; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Regulatory Sequences, Nucleic Acid; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcription Factors | 2004 |
Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines.
Topics: Adenocarcinoma; Animals; Azacitidine; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Fibroblasts; Gene Silencing; Histiocytoma, Benign Fibrous; Lung Neoplasms; Neoplasms; Osteosarcoma; Promoter Regions, Genetic; Rats; RNA, Messenger; Sulfites; TATA Box; Tumor Cells, Cultured | 2004 |
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
Topics: Adenocarcinoma; Alleles; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Separation; Cell Transformation, Neoplastic; Decitabine; DNA Methylation; DNA Mutational Analysis; DNA, Complementary; Exons; Flow Cytometry; Genes, Tumor Suppressor; Humans; Loss of Heterozygosity; Oxidoreductases; Pancreatic Neoplasms; Promoter Regions, Genetic; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tumor Suppressor Proteins; WW Domain-Containing Oxidoreductase | 2004 |
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer.
Topics: Adenocarcinoma; Apoptosis; Azacitidine; Cell Hypoxia; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Glucose Transport Proteins, Facilitative; Humans; Insulin-Like Growth Factor Binding Protein 3; Membrane Proteins; Monosaccharide Transport Proteins; Pancreas; Pancreatic Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins; Tumor Cells, Cultured | 2004 |
Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Decitabine; DNA Primers; Glycoproteins; Humans; Hydroxamic Acids; Loss of Heterozygosity; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2005 |
Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; CpG Islands; Decitabine; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Stomach Neoplasms; Tumor Cells, Cultured | 2004 |
Abrogation of DUSP6 by hypermethylation in human pancreatic cancer.
Topics: Acetylation; Adenocarcinoma; Azacitidine; Base Sequence; Carcinoma, Pancreatic Ductal; Cell Differentiation; CpG Islands; DNA Methylation; Dual Specificity Phosphatase 6; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Molecular Sequence Data; Neoplasm Invasiveness; Pancreatic Neoplasms; Protein Tyrosine Phosphatases; Tumor Cells, Cultured | 2005 |
Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Carrier Proteins; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Membrane Glycoproteins; Pancreas; Pancreatic Ducts; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2005 |
Epigenetic-mediated upregulation of progesterone receptor B gene in endometrial cancer cell lines.
Topics: Adenocarcinoma; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Endometrial Neoplasms; Enzyme Inhibitors; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Polymerase Chain Reaction; Receptors, Progesterone; RNA, Messenger; Up-Regulation | 2005 |
DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Carcinoma, Adenosquamous; DNA Methylation; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Intestinal Neoplasms; Male; Membrane Proteins; Metaplasia; Middle Aged; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoids; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured | 2005 |
Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus.
Topics: Adenocarcinoma; Azacitidine; Barrett Esophagus; beta Catenin; Cell Division; Cell Line, Tumor; CpG Islands; Decitabine; Disease Progression; DNA Methylation; DNA, Neoplasm; Esophageal Neoplasms; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, APC; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Mucous Membrane; Neoplasm Proteins; Precancerous Conditions; Promoter Regions, Genetic; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Signal Transduction; Transfection; Wnt Proteins; Wnt2 Protein | 2006 |
Hypomethylation of the protein gene product 9.5 promoter region in gallbladder cancer and its relationship with clinicopathological features.
Topics: Adenocarcinoma; Adenoma; Azacitidine; CpG Islands; DNA Methylation; DNA, Neoplasm; Gallbladder Neoplasms; Humans; Immunoenzyme Techniques; Microdissection; Neoplasm Invasiveness; Neoplasm Staging; Polymerase Chain Reaction; Promoter Regions, Genetic; Tissue Array Analysis; Tumor Cells, Cultured; Ubiquitin Thiolesterase | 2006 |
Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma.
Topics: Adenocarcinoma; Azacitidine; Carcinoma, Squamous Cell; Case-Control Studies; Cell Proliferation; Colony-Forming Units Assay; DNA Methylation; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Nasopharyngeal Neoplasms; Nasopharynx; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2007 |
Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.
Topics: Adenocarcinoma; Adult; Aged; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; Cyclin D2; Cyclins; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 2006 |
Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.
Topics: Acetylation; Adenocarcinoma; Azacitidine; Biomarkers, Tumor; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chromatin Immunoprecipitation; Colony-Forming Units Assay; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2007 |
Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression.
Topics: Adenocarcinoma; Aged; Azacitidine; Barrett Esophagus; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Decitabine; Disease Progression; DNA Methylation; Esophageal Diseases; Esophageal Neoplasms; Female; Genetic Markers; Glycoproteins; Humans; Male; Middle Aged; Polymerase Chain Reaction; Precancerous Conditions | 2006 |
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Breast Neoplasms; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Cathepsin K; Cathepsins; Colonic Neoplasms; CpG Islands; Cyclin A; Cyclin A1; Decitabine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Profiling; Humans; Lung Neoplasms; Male; Middle Aged; MSX1 Transcription Factor; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Prostatic Neoplasms; Transcription Factors; Tumor Cells, Cultured | 2006 |
Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; CpG Islands; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Male; Middle Aged; Promoter Regions, Genetic; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 2007 |
Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer.
Topics: Adenocarcinoma; Apoptosis; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; DNA Modification Methylases; DNA, Neoplasm; Epithelial Cells; Humans; Immunohistochemistry; Insulin-Like Growth Factor Binding Proteins; Lung; Lung Neoplasms; Microarray Analysis; Neoplasm Staging; Transfection; Tumor Suppressor Proteins | 2007 |
Potential target antigens for immunotherapy in human pancreatic cancer.
Topics: Adenocarcinoma; Antigens, Neoplasm; Azacitidine; Base Sequence; DNA Primers; Humans; Immunotherapy; Pancreatic Neoplasms | 2007 |
5-aza-2'-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azacitidine; Castration; Combined Modality Therapy; Decitabine; Disease Models, Animal; Male; Mice; Mice, Transgenic; Neoplasms, Hormone-Dependent; Prostatic Neoplasms | 2007 |
[Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines].
Topics: Adenocarcinoma; Adenomatous Polyposis Coli Protein; Azacitidine; Carcinoma, Large Cell; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Genes, APC; Humans; Lung Neoplasms; Promoter Regions, Genetic; Small Cell Lung Carcinoma; Transcription, Genetic | 2007 |
Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; RNA, Small Interfering; Stomach Neoplasms; Transfection | 2007 |
Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma.
Topics: Adenocarcinoma; Aged; Azacitidine; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 7; Decitabine; DNA Methylation; Enzyme Inhibitors; Estrogen Receptor beta; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Middle Aged; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Steroid Hydroxylases | 2007 |
Epigenetic inactivation of the CHFR gene in cervical cancer contributes to sensitivity to taxanes.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Bridged-Ring Compounds; Carcinoma, Squamous Cell; Cell Cycle Proteins; DNA Methylation; DNA, Neoplasm; Drug Tolerance; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Neoplasm Proteins; Poly-ADP-Ribose Binding Proteins; Promoter Regions, Genetic; RNA, Small Interfering; Taxoids; Tumor Cells, Cultured; Ubiquitin-Protein Ligases; Uterine Cervical Neoplasms | 2007 |
Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Animals; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; DNA Methylation; DNA Primers; Epigenesis, Genetic; Eye Proteins; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Nude; Promoter Regions, Genetic; Proto-Oncogene Proteins; Stomach Neoplasms | 2007 |
[The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor].
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenoma; Adult; Aged; Azacitidine; Cell Line, Tumor; Colorectal Neoplasms; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Glycoproteins; HCT116 Cells; Humans; Hydroxamic Acids; Intestinal Mucosa; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer.
Topics: Adenocarcinoma; Azacitidine; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Chromosomes, Human, Pair 18; Colorectal Neoplasms; Cyclins; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Loss of Heterozygosity; Mutation; Phosphoproteins; Promoter Regions, Genetic | 2007 |
Methylation silencing of transforming growth factor-beta receptor type II in rat prostate cancers.
Topics: Adenocarcinoma; Animals; Azacitidine; Cell Line, Tumor; Decitabine; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Histones; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Up-Regulation | 2008 |
[Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor].
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenoma; Adult; Aged; Azacitidine; Biomarkers, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Decitabine; DNA Methylation; DNA Modification Methylases; Eye Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; HCT116 Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Male; Membrane Proteins; Middle Aged; RNA, Messenger | 2007 |
Progressive silencing of p14ARF in oesophageal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Barrett Esophagus; Base Sequence; Cell Line; Decitabine; Disease Progression; Epithelial Cells; Esophageal Neoplasms; Female; Gene Silencing; Histones; Humans; Male; Methylation; Middle Aged; Molecular Sequence Data; Survival Rate; Tumor Suppressor Protein p14ARF | 2009 |
Sequential combination of pyrazofurin and 5-azacytidine in patients with acute myelocytic leukemia and carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Amides; Azacitidine; Carcinoma; Carcinoma, Small Cell; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Lung Neoplasms; Male; Middle Aged; Pyrazoles; Ribonucleosides; Ribose | 1981 |
5-Aza-2'-deoxycytidine induces growth inhibition and upregulation of epidermal growth factor receptor on human epithelial cancer cells.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Division; Decitabine; Endocytosis; ErbB Receptors; Humans; KB Cells; Tumor Cells, Cultured; Up-Regulation | 1994 |
The differential expression of cytokeratin 18 in cisplatin-sensitive and -resistant human ovarian adenocarcinoma cells and its association with drug sensitivity.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Cisplatin; DNA Damage; Drug Resistance; Female; Humans; Keratins; Ovarian Neoplasms; Tumor Cells, Cultured | 1995 |
Evaluation of the antineoplastic activity of adozelesin alone and in combination with 5-aza-2'-deoxycytidine and cytosine arabinoside on DLD-1 human colon carcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzofurans; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Cyclohexanecarboxylic Acids; Cyclohexenes; Cytarabine; Decitabine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Duocarmycins; Humans; Indoles; Lung Neoplasms; Time Factors; Tumor Cells, Cultured | 1993 |
Activation of the retinoic acid receptor beta gene by 5-aza-2'-deoxycytidine in human DLD-1 colon carcinoma cells.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blotting, Northern; Blotting, Southern; Cell Line; Colonic Neoplasms; Decitabine; DNA Methylation; Exons; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Receptors, Retinoic Acid; Tretinoin; Tumor Stem Cell Assay | 1997 |
Alterations of p16INK4A and p15INK4B genes in gastric carcinomas.
Topics: Adenocarcinoma; Azacitidine; Carrier Proteins; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA Mutational Analysis; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1997 |
5-Azacytidine modulates gamma-glutamyltransferase and glutathione levels in two human prostatic adenocarcinoma cell lines.
Topics: Adenocarcinoma; Azacitidine; Blotting, Southern; DNA Methylation; DNA, Neoplasm; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Liver; Male; Placenta; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1998 |
Frequent alteration of CDKN2 (p16(INK4A)/MTS1) expression in human primary prostate carcinomas.
Topics: Adenocarcinoma; Animals; Azacitidine; Blotting, Western; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, Retinoblastoma; Humans; Male; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Prostatic Hyperplasia; Prostatic Neoplasms; Retinoblastoma Protein; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells.
Topics: 5-Methylcytosine; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tumor Cells, Cultured | 1998 |
Differential expression of MHC class II genes in lung tumour cell lines.
Topics: Actins; Adenocarcinoma; Antibodies, Monoclonal; Azacitidine; Blotting, Northern; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Decitabine; Densitometry; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression; Genes, MHC Class II; Genes, myc; HLA-DP Antigens; HLA-DQ Antigens; HLA-DR Antigens; Humans; Interferon-gamma; Lung Neoplasms; Proto-Oncogene Mas; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Colonic Neoplasms; Decitabine; DNA Methylation; Gene Expression Regulation; HT29 Cells; Humans; Neoplasm Metastasis; S100 Calcium-Binding Protein A4; S100 Proteins; Transcriptional Activation; Tumor Cells, Cultured | 1998 |
Loss of imprinting and elevated expression of wild-type p73 in human gastric adenocarcinoma.
Topics: Adenocarcinoma; Alleles; Azacitidine; Culture Media, Serum-Free; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Decitabine; DNA-Binding Proteins; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genomic Imprinting; HL-60 Cells; Humans; Mutation; Nuclear Proteins; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; U937 Cells | 2000 |
Methylation of specific CpG sites in the promoter region could significantly down-regulate p16(INK4a) expression in gastric adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Northern; Blotting, Southern; Carrier Proteins; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Down-Regulation; Female; Humans; Immunohistochemistry; Male; Middle Aged; Models, Genetic; Mutagens; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Stomach Neoplasms; Sulfites; Tumor Cells, Cultured | 2000 |
Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells.
Topics: Adenocarcinoma; Azacitidine; Base Sequence; Breast Neoplasms; Clone Cells; CpG Islands; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Molecular Sequence Data; Neoplasm Proteins; Promoter Regions, Genetic; Receptors, Retinoic Acid; Sequence Analysis, DNA; Transcriptional Activation; Transfection; Tretinoin; Tumor Cells, Cultured | 2000 |
Hypermethylation of the p16 (Ink4a) promoter in B6C3F1 mouse primary lung adenocarcinomas and mouse lung cell lines.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Azacitidine; Carrier Proteins; Cell Division; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression; Genes, Tumor Suppressor; Immunohistochemistry; Loss of Heterozygosity; Lung Neoplasms; Mice; Mice, Inbred A; Mice, Inbred C3H; Mice, Inbred C57BL; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2000 |
Inactivation of the 14-3-3 sigma gene is associated with 5' CpG island hypermethylation in human cancers.
Topics: 14-3-3 Proteins; Adenocarcinoma; Alleles; Animals; Azacitidine; Biomarkers, Tumor; Cell Cycle; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Exonucleases; Exoribonucleases; Fluorescence; G2 Phase; Gene Expression; Gene Silencing; Genes, p53; Humans; Mice; Mice, SCID; Neoplasm Proteins; Neoplasm Transplantation; Nucleic Acid Conformation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Protein Biosynthesis; Proteins; Stomach Neoplasms; Sulfites; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Repression of transforming growth factor-beta receptor type I promoter expression by Sp1 deficiency.
Topics: Activin Receptors, Type I; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Colonic Neoplasms; Cyclin A; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Sp1 Transcription Factor; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2000 |
Induction of MAGE-3 expression in lung and esophageal cancer cells.
Topics: Adenocarcinoma; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antigens, Neoplasm; Azacitidine; Carcinoma, Non-Small-Cell Lung; Decitabine; Depsipeptides; DNA Modification Methylases; Enzyme Inhibitors; Esophageal Neoplasms; Histone Deacetylase Inhibitors; Humans; Immunohistochemistry; Lung Neoplasms; Melanoma; Neoplasm Proteins; Peptides, Cyclic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2001 |
Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines.
Topics: Adenocarcinoma; Antigens, CD; Azacitidine; Base Sequence; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Kangai-1 Protein; Male; Membrane Glycoproteins; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Proto-Oncogene Proteins; Sulfites; Tumor Cells, Cultured | 2001 |
Reduced expression of syndecan-1 affects metastatic potential and clinical outcome in patients with colorectal cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azacitidine; Chi-Square Distribution; Colorectal Neoplasms; Decitabine; Female; Humans; Immunohistochemistry; In Situ Hybridization; Intestinal Mucosa; Lymphatic Metastasis; Male; Membrane Glycoproteins; Methylation; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Proteoglycans; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Syndecan-1; Syndecans; Tumor Cells, Cultured | 2001 |
Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Azacitidine; Binding Sites; Carrier Proteins; CCAAT-Binding Factor; Colorectal Neoplasms; CpG Islands; Decitabine; DNA Methylation; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Luciferases; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Recombinant Fusion Proteins; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2001 |
Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; DNA Primers; DNA, Neoplasm; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Adhesion Molecule-1; Loss of Heterozygosity; Methylation; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Prognosis; RNA, Messenger; Survival Analysis; Tumor Cells, Cultured | 2001 |
Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; CpG Islands; Cyclin G; Cyclin G1; Cyclins; DNA Methylation; Enkephalins; Humans; Microsatellite Repeats; Middle Aged; Pancreatic Neoplasms; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Synergistic cytotoxicity with 2'-deoxy-5-azacytidine and topotecan in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Colorectal Neoplasms; Decitabine; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lethal Dose 50; Methylation; Mice; Mice, Inbred BALB C; Topotecan; Tumor Cells, Cultured | 1992 |
Absence of tRNA-guanine transglycosylase in a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Animals; Azacitidine; Cell Cycle; Colonic Neoplasms; Guanine; Humans; Mice; Mutation; Neoplasm Transplantation; Pentosyltransferases; Rhabdomyosarcoma; RNA Processing, Post-Transcriptional; RNA, Transfer; Tumor Cells, Cultured | 1992 |
Outgrowth of stable class I major histocompatibility complex-expressing subsets from immunogenic variants of a murine mammary carcinoma: association with a differentially staining region on chromosome 9.
Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Azacitidine; Biomarkers, Tumor; Chromosome Mapping; Clone Cells; Female; Genetic Markers; Graft Rejection; H-2 Antigens; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred CBA; Mice, Nude; Neoplasm Transplantation; Phenotype | 1991 |
Effects of nucleoside analogs and sodium butyrate on recovery from potentially lethal X ray damage in human colon tumor cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Butyrates; Butyric Acid; Cells, Cultured; Colon; Colonic Neoplasms; Decitabine; Humans; Radiation-Sensitizing Agents | 1987 |
5-Azacytidine induction of stable myoepithelial and acinar cells from a human salivary intercalated duct cell clone.
Topics: Adenocarcinoma; Amylases; Animals; Azacitidine; Cell Differentiation; Clone Cells; DNA; Humans; Methylation; Mice; Mice, Inbred BALB C; Myosins; Neoplasm Transplantation; Salivary Gland Neoplasms; Transplantation, Heterologous | 1987 |
In situ augmentation of class I major histocompatibility antigen expression on immunogenic variants of a spontaneous murine mammary carcinoma.
Topics: Adenocarcinoma; Animals; Azacitidine; Decitabine; Female; Graft Rejection; Histocompatibility Antigens; Histocompatibility Antigens Class II; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Neoplasm Transplantation | 1987 |