azacitidine and Acute Promyelocytic Leukemia

azacitidine has been researched along with Acute Promyelocytic Leukemia in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (31.58)18.2507
2000's5 (26.32)29.6817
2010's5 (26.32)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Dai, H; Gao, X; Li, Y; Wang, W; Xue, Y; Yao, D1
Herold, T; Hiddemann, W; Rausch, C; Spiekermann, K; von Bergwelt-Baildon, M1
Baker, K; Banos, A; Bixby, D; Braun, T; Carulli, J; Cluzeau, T; Cook, RJ; de Botton, S; Eaton, M; Fenaux, P; Fiore, C; Hodgson, G; Jurcic, JG; Kang-Fortner, Q; Kelly, MJ; Liesveld, JL; Madigan, K; McKeown, M; Paul, S; Rizzieri, DA; Roboz, GJ; Roth, DA; Rousselot, P; Savona, MR; Sekeres, MA; Stein, EM; Stephens, K; Vigil, C; Volkert, A1
Abboud, CN; Cashen, AF; Dipersio, JF; Jacoby, M; Niu, H; Pusic, I; Schroeder, MA; Stockerl-Goldstein, KE; Uy, GL; Vij, R; Welch, JS; Westervelt, P1
Wiernik, PH1
Jaksic, O; Kusec, R; Lasan-Trcic, R; Lucijanic, M; Pejsa, V; Stoos-Veic, T1
Chen, JJ; Chen, Y; Lin, DJ; Long, ZJ; Wu, X; Xiao, RZ; Xiong, MJ1
Luo, Q; Su, Y; Xian, Y; Xu, H; Xu, Y; Yu, J1
Chan, WW; Chim, CS; Kwong, YL; Pang, A1
Andreeff, M; Contractor, R; Issa, JP; Jin, L; Kondo, Y; Konopleva, M; Miyake, K; Miyake, N; Nagaoka, I; Ohsaka, A; Ruvolo, V; Tabe, Y; Tsutsumi-Ishii, Y1
Santini, V1
Darzynkiewicz, Z; Del Bino, G; Li, X; Traganos, F1
Bhatia, U; Darzynkiewicz, Z; Gong, J; Li, X; Murakami, T; Traganos, F1
He, ZX; Rao, H1
Ayabe, H; Darzynkiwicz, Z; Hara, S; Tagawa, Y1
Marx, J1
Corsaro, M; Di Croce, L; Fanelli, M; Faretta, M; Fazi, F; Fuks, F; Kouzarides, T; Lo Coco, F; Minucci, S; Nervi, C; Pelicci, PG; Raker, VA1
Samid, D; Shack, S; Sherman, LT1
Laliberté, J; Momparler, RL1

Reviews

2 review(s) available for azacitidine and Acute Promyelocytic Leukemia

ArticleYear
Inching toward cure of acute myeloid leukemia: a summary of the progress made in the last 50 years.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:8

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Molecular Targeted Therapy; Prognosis; Remission Induction; Treatment Outcome

2014
A selective activity of DNMTi decitabine on AML1ETO positive cells?
    Leukemia research, 2007, Volume: 31, Issue:6

    Topics: Animals; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Core Binding Factor Alpha 2 Subunit; Cyclin-Dependent Kinase Inhibitor p15; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Humans; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion; RUNX1 Translocation Partner 1 Protein

2007

Trials

1 trial(s) available for azacitidine and Acute Promyelocytic Leukemia

ArticleYear
A phase I dose escalation study of oral bexarotene in combination with intravenous decitabine in patients with AML.
    American journal of hematology, 2014, Volume: 89, Issue:8

    Topics: Administration, Oral; Aged; Aged, 80 and over; Animals; Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Azacitidine; Bexarotene; Decitabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Gene Expression; Gene Expression Profiling; Humans; Injections, Intravenous; Leukemia, Promyelocytic, Acute; Male; Mice; Middle Aged; Receptors, Retinoic Acid; Recurrence; Retinoic Acid Receptor alpha; Retinoid X Receptor alpha; Tetrahydronaphthalenes; Tumor Cells, Cultured

2014

Other Studies

16 other study(ies) available for azacitidine and Acute Promyelocytic Leukemia

ArticleYear
Central nervous system relapse of acute promyelocytic leukemia treated by oral Venetoclax with Azacitidine achieved complete remission.
    Annals of hematology, 2022, Volume: 101, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Recurrence; Remission Induction; Sulfonamides

2022
[Acute Myeloid Leukemia - Update 2022].
    Deutsche medizinische Wochenschrift (1946), 2022, Volume: 147, Issue:17

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Azacitidine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Tretinoin

2022
Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML.
    Blood advances, 2023, 05-09, Volume: 7, Issue:9

    Topics: Azacitidine; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes; Retinoic Acid Receptor alpha

2023
Loss of response to azacitidine is associated with deletion 12p13 in a patient with myelodysplastic syndrome with unique translocation t(13;17)(q12;q25) after prior breast cancer and acute promyelocytic leukemia.
    Annals of hematology, 2015, Volume: 94, Issue:9

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast Neoplasms; Chromosome Deletion; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 13; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Translocation, Genetic

2015
[Decitabine inhibits cell proliferation and induces apoptosis of all-trans retinoid acid-resistant acute promyelocytic leukemia NB4-R2 cell line].
    Zhongguo shi yan xue ye xue za zhi, 2012, Volume: 20, Issue:1

    Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Tretinoin

2012
Azacytidine inhibits the proliferation of human promyelocytic leukemia cells (HL60) by demethylation of MGMT, DAPK and p16 genes.
    Hematology (Amsterdam, Netherlands), 2012, Volume: 17, Issue:1

    Topics: Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Growth Processes; Cell Line, Tumor; CpG Islands; Death-Associated Protein Kinases; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Genes, p16; Genes, Regulator; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Promoter Regions, Genetic; Tumor Suppressor Proteins

2012
Preferential methylation of Wnt inhibitory factor-1 in acute promyelocytic leukemia: an independent poor prognostic factor.
    Leukemia, 2006, Volume: 20, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia, Promyelocytic, Acute; Methylation; Multivariate Analysis; Prognosis; Recurrence; Remission Induction; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Sensitivity and Specificity; Survival Rate; Tretinoin; Tumor Cells, Cultured

2006
PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
    Annals of hematology, 2006, Volume: 85, Issue:10

    Topics: Antineoplastic Agents; Azacitidine; Core Binding Factor Alpha 2 Subunit; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Histone Deacetylases; HL-60 Cells; Humans; K562 Cells; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; RNA, Messenger; RNA, Neoplasm; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic; Tretinoin; U937 Cells

2006
Altered susceptibility of differentiating HL-60 cells to apoptosis induced by antitumor drugs.
    Leukemia, 1994, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Camptothecin; Cell Cycle; Cell Differentiation; Dimethyl Sulfoxide; DNA, Neoplasm; Humans; Hyperthermia, Induced; Leukemia, Promyelocytic, Acute; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

1994
Induction of apoptosis by 5-azacytidine: drug concentration-dependent differences in cell cycle specificity.
    Cancer research, 1995, Jul-15, Volume: 55, Issue:14

    Topics: Apoptosis; Azacitidine; Cell Cycle; DNA Replication; DNA, Neoplasm; Flow Cytometry; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Sensitivity and Specificity; Tumor Cells, Cultured

1995
The effect of 5-azacytidine (5-aza-CR) and its analogue on cell differentiation and DNA methylation of HL-60 cells.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1993, Volume: 36, Issue:4

    Topics: Antineoplastic Agents; Azacitidine; Cell Differentiation; Decitabine; DNA-Cytosine Methylases; DNA-Directed RNA Polymerases; DNA, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Methylation; Tumor Cells, Cultured

1993
[Analysis of drug-induced apoptosis in human leukemic cell line (HL-60)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25 Suppl 3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Camptothecin; Cell Cycle; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Tosylphenylalanyl Chloromethyl Ketone

1998
Cancer research. Leukemia protein spurs gene silencing.
    Science (New York, N.Y.), 2002, Feb-08, Volume: 295, Issue:5557

    Topics: Azacitidine; Cell Division; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, Tumor Suppressor; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mutation; Neoplasm Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin; Zinc

2002
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.
    Science (New York, N.Y.), 2002, Feb-08, Volume: 295, Issue:5557

    Topics: Azacitidine; Binding Sites; Cell Differentiation; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cloning, Molecular; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Exons; Gene Expression; Gene Silencing; Histone Deacetylases; Humans; Leukemia, Promyelocytic, Acute; Mutation; Neoplasm Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Transcription Factors; Tretinoin; Tumor Cells, Cultured; Zinc

2002
Phenylacetate: a novel nontoxic inducer of tumor cell differentiation.
    Cancer research, 1992, Apr-01, Volume: 52, Issue:7

    Topics: Adipose Tissue; Animals; Antineoplastic Agents; Azacitidine; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Decitabine; Gene Expression; Genes, myc; Humans; Leukemia, Promyelocytic, Acute; Mice; Mice, Nude; Phenylacetates; RNA, Ribosomal

1992
Induction of cytidine deaminase in HL-60 myeloid leukemic cells by 5-aza-2'-deoxycytidine.
    Leukemia research, 1990, Volume: 14, Issue:9

    Topics: Antineoplastic Agents; Azacitidine; Cell Differentiation; Cytidine Deaminase; Decitabine; DNA, Neoplasm; Enzyme Induction; Humans; Leukemia, Promyelocytic, Acute; Tumor Cells, Cultured

1990