azacitidine and Acute Liver Injury, Drug-Induced

azacitidine has been researched along with Acute Liver Injury, Drug-Induced in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dai, J; Ge, P; Gong, X; Lin, L; Xing, Y; Yang, C; Yi, J; Zhang, L1
Bai, W; Gao, A; Niu, P; Tian, L; Yang, J; Zuo, X1
Schlenk, RF; Thol, F1
Benton, CB; Borthakur, G; Dara, S; Franklin, AR; Garcia-Manero, G; Jabbour, E; Kantarjian, H; Kwari, M; O'Brien, S; Pierce, SR; Ravandi, F; Rytting, M; Thomas, DA; Yang, H1
Briggs, JE; Clouser, CL; Crankshaw, DL; Holtz, CM; Mansky, LM; Mullett, M; O'Sullivan, MG; Patterson, SE1
Aung, L; Kirk, RC; Liang, S; Quah, TC; Tan, RM; Yeoh, AE1
Bueso-Ramos, C; Cortes, J; Davis, J; Estrov, Z; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Giles, F; Huang, X; Issa, JP; Kantarjian, H; O'Brien, S; Oki, Y; Ravandi, F; Saba, HI; Shan, J; Wierda, W1
Case, DC1
Robak, T1
Muggia, FM; Slavik, M; Von Hoff, DD1
Bellet, RE; Custer, RP; Engstrom, PF; Mastrangelo, MJ1

Reviews

3 review(s) available for azacitidine and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Gemtuzumab ozogamicin in acute myeloid leukemia revisited.
    Expert opinion on biological therapy, 2014, Volume: 14, Issue:8

    Topics: Age Factors; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Gemtuzumab; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Recurrence; Treatment Failure

2014
5-Azacytidine. A new anticancer drug with effectiveness in acute myelogenous leukemia.
    Annals of internal medicine, 1976, Volume: 85, Issue:2

    Topics: Animals; Azacitidine; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Europe; Female; Humans; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Liver; Nausea; Neoplasms, Experimental; Neuromuscular Diseases; RNA, Messenger; United States; Vomiting

1976

Trials

3 trial(s) available for azacitidine and Acute Liver Injury, Drug-Induced

ArticleYear
Safety and clinical activity of 5-aza-2'-deoxycytidine (decitabine) with or without Hyper-CVAD in relapsed/refractory acute lymphocytic leukaemia.
    British journal of haematology, 2014, Volume: 167, Issue:3

    Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Decitabine; Dexamethasone; DNA Methylation; DNA, Neoplasm; Doxorubicin; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Hyperglycemia; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Methotrexate; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Vincristine; Young Adult

2014
Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia.
    Blood, 2007, Jan-01, Volume: 109, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Bayes Theorem; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Cyclin-Dependent Kinase Inhibitor p15; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm Proteins; Remission Induction; Risk; Treatment Outcome

2007
[Clinical pharmacology of 5-azacytidine].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1984, Feb-13, Volume: 39, Issue:7

    Topics: Adult; Animals; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Dogs; Drug Evaluation, Preclinical; Hepatitis, Animal; Humans; Leukemia, Myeloid, Acute; Mice

1984

Other Studies

10 other study(ies) available for azacitidine and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Anti-oxidative and anti-inflammatory benefits of the ribonucleoside analogue 5-azacitidine in mice with acetaminophen-induced toxic hepatitis.
    International immunopharmacology, 2017, Volume: 48

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Azacitidine; Chemical and Drug Induced Liver Injury; Glutathione; Interleukin-6; Liver; Male; Malondialdehyde; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Peroxidase; Tumor Necrosis Factor-alpha

2017
PTEN methylation involved in benzene-induced hematotoxicity.
    Experimental and molecular pathology, 2014, Volume: 96, Issue:3

    Topics: Animals; Azacitidine; Benzene; Body Weight; Carcinogens; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Genes, Tumor Suppressor; Hydroxamic Acids; Leukocytes; Male; Promoter Regions, Genetic; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation

2014
Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:4

    Topics: Animals; Anti-HIV Agents; Azacitidine; Body Weight; Cells, Cultured; Chemical and Drug Induced Liver Injury; Decitabine; Deoxycytidine; Drug Combinations; Drug Synergism; Female; Flow Cytometry; Gemcitabine; HIV-1; Humans; Liver; Lymph Nodes; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Proviruses; Spleen; T-Lymphocytes; Transfection

2012
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Drug Evaluation; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Infant; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Prednisone; Remission Induction; Retrospective Studies; Singapore; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine

2007
5-azacytidine in refractory acute leukemia.
    Oncology, 1982, Volume: 39, Issue:4

    Topics: Acute Disease; Adult; Aged; Agranulocytosis; Azacitidine; Chemical and Drug Induced Liver Injury; Humans; Infusions, Parenteral; Leukemia; Leukemia, Myeloid; Middle Aged; Muscular Diseases

1982
Hepatotoxicity of 5-azacytidine (NSC-102816) (a clinical and pathologic study).
    Neoplasma, 1973, Volume: 20, Issue:3

    Topics: Acute Disease; Adult; Aged; Azacitidine; Chemical and Drug Induced Liver Injury; Cytidine; Female; Humans; Kupffer Cells; Liver; Male; Middle Aged; Neoplasms; Triazines

1973