azacitidine has been researched along with Abnormalities, Autosome in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (11.11) | 18.7374 |
1990's | 13 (18.06) | 18.2507 |
2000's | 14 (19.44) | 29.6817 |
2010's | 35 (48.61) | 24.3611 |
2020's | 2 (2.78) | 2.80 |
Authors | Studies |
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Fujii, F; Kakinoki, Y; Matsuoka, S; Nojima, S | 1 |
Dvořák Tomaštíková, E; Ercan, U; Finke, A; Krečmerová, M; Niezgodzki, I; Nowicka, A; Otmar, M; Pecinka, A; Poppenberger, B; Procházková, K; Rozhon, W; Schubert, I; Tokarz, B; Zwyrtková, J | 1 |
Anguita, E; Bernal, T; Bulnes, PD; Colado, E; Garay, MCG; Gil, AC; Lopez-Larrea, C; Marin, AM; Márquez-Kisinousky, L; Minguela, A; Mogorron, AV; Raneros, AB; Rodriguez, RM; Suarez-Alvarez, B; Vidal-Castiñeira, JR | 1 |
Adès, L; Ali, NH; Cluzeau, T; Eclache, V; Fenaux, P; Gyan, E; Hobson, S; Komrokji, RS; List, A; Prebet, T; Sanna, A; Santini, V; Sébert, M; Sekeres, MA | 1 |
Dombret, H; Itzykson, R | 1 |
Ame, S; Badiella, L; Bargay, J; Berthon, C; Beyne-Rauzy, O; Bordessoule, D; Cañizo, C; Cedena, T; de Botton, S; Delaunay, J; Díez-Campelo, M; Fenaux, P; Guieze, R; Gyan, E; Hernández-Rivas, JM; Isnard, F; Itzykson, R; López-Cadenas, F; Lorenzo, JI; Luño, E; Muñoz, JA; Park, S; Pérez Guallar, J; Perez-Oteyza, J; Rojas, SM; Salanoubat, C; Sanz, G; Stamatoullas, A; Such, E; Vey, N; Visanica, S | 1 |
Arellano, M; Carlisle, JW | 1 |
Chantepie, SP; Charbonnier, A; Gruson, B; Harrivel, V; Ivanoff, S; Lemasle, E; Marolleau, JP; Merlusca, L; Royer, B; Votte, P | 1 |
Blau, IW; Böhme, A; Braulke, F; Brümmendorf, TH; Bug, G; Detken, S; Ganster, C; Germing, U; Giagounidis, AA; Götze, K; Haase, D; Hofmann, WK; Jentsch-Ullrich, K; Jung, K; Lübbert, M; Metz, M; Müller-Thomas, C; Ottmann, O; Pfeiffer, S; Platzbecker, U; Schafhausen, P; Schanz, J; Schlenk, RF; Schmidt, B; Seraphin, J; Shirneshan, K; Stadler, M; Trümper, L | 1 |
Brioli, A; Davies, FE; Johnson, DC; Kaiser, MF; Melchor, L; Mirabella, F; Morgan, GJ; Walker, BA; Wardell, CP; Wu, P | 1 |
Chang, C; He, Q; Li, X; Song, L; Su, J; Wu, D; Wu, L; Xu, F; Zhang, Q; Zhang, X; Zhang, Z; Zhou, L | 1 |
Saunthararajah, Y | 1 |
Li, J; Liu, J; Su, C; Tong, X; Zheng, D; Zhou, Z | 1 |
Berthon, C; Delaunay, J; Dreyfus, F; Esterni, B; Fenaux, P; Itzykson, R; Kulasekararaj, A; Micol, JB; Mufti, G; Prebet, T; Recher, C; Roux, C; Sebert, M; Thepot, S; Vey, N; Wanquet, A | 1 |
Goes, FS; Ishizuka, K; Kano, S; Koga, M; Kondo, MA; Obie, C; Passeri, E; Primerano, A; Rapoport, JL; Sawa, A; Sengupta, S; Srivastava, R; Valle, D; Wilson, AM; Zandi, PP | 1 |
Braulke, F; Ganster, C; Haase, D; Platzbecker, U; Salinas-Riester, G; Schanz, J; Shirneshan, K | 1 |
Garcia-Manero, G; Goswami, M; Hasserjian, RP; Jabbour, EJ; Medeiros, LJ; Patel, KP; Peng, J; Tang, G; Wang, SA | 1 |
Dou, MH; Hu, C; Huang, J; Jin, J; Li, Y; Lou, YJ; Luo, YW; Ma, LY; Mao, LP; Mei, C; Niu, LM; Ren, YL; Tong, HY; Wang, JH; Wei, JY; Xie, LL; Xu, GX; Ye, L; Ye, XN; Yu, WJ; Zhou, XP | 1 |
Harada, Y; Ito, M; Iwasaki, T; Kurahashi, S; Nishiwaki, S; Okuno, S; Sugiura, I; Suzuki, K; Watarai, R; Yamamoto, S | 1 |
Barra, V; Cilluffo, D; Costa, G; Di Leonardo, A; Lentini, L | 1 |
Aoyama, Y; Hino, M; Ichihara, H; Ido, K; Manabe, M; Mugitani, A; Nagasaki, J; Ohta, T | 1 |
Ando, T; Kimura, S; Kizuka, H; Kojima, K; Kubota, Y; Kusaba, K; Nishioka, A; Sano, H; Shindo, T; Ureshino, H | 1 |
Chang, CK; Guo, J; He, Q; Li, X; Song, LX; Su, JY; Wu, D; Wu, LY; Xiao, C; Xu, F; Zhang, Z; Zhao, YS | 1 |
Chang, CK; Guo, J; Li, X; Song, LL; Wu, D; Wu, LY; Xiao, C; Xu, F; Zhao, YS | 1 |
Borthakur, G; Cortes, J; Faderl, S; Garcia-Manero, G; Issa, JP; Kantarjian, H; O'Brien, S; Pierce, S; Ravandi, F; Shan, J; Verstovsek, S | 1 |
Artigas, R; de Bethencourt, M; Iriarte, A; Iriarte, W; Llambí, S; Postiglioni, A | 1 |
Braulke, F; Haase, D; Jung, K; Schanz, J; Schuetze, C; Schulte, K; Shirneshan, K; Steffens, R; Trümper, L | 1 |
Manna, S; Mukherjee, P; Mukherjee, S; Pal, D; Panda, CK | 1 |
Afable, M; Cuthbertson, D; Ganetsky, R; Ganetzky, R; Latham, D; List, AF; Loughran, TP; Maciejewski, JP; Paquette, R; Paulic, K; Saba, HI; Sekeres, MA | 1 |
Ebert, BL | 1 |
Castoro, R; Chung, W; El Ahdab, S; He, R; Issa, JP; Jelinek, J; Kantarjian, HM; Qin, T; Shu, J; Si, J; Wang, X; Zhang, N | 1 |
Horiike, S; Kuroda, J; Nagoshi, H; Taniwaki, M | 1 |
Chan, KW; Lockhart, S; McDonald, L; Rytting, M | 1 |
Castro, C; Fabián, E; González, R; Herrera, LA; Prada, D; Sánchez, L | 1 |
Parikh, SA; Tefferi, A | 1 |
Barreyro, L; Ben-Neriah, S; Bhagat, TD; Bhattacharyya, S; Boultwood, J; Greally, JM; Heuck, C; List, AF; Maciejewski, J; McMahon, C; Mo, Y; Montagna, C; Parekh, S; Pellagatti, A; Schinke, C; Silverman, L; Steidl, C; Steidl, U; Tamari, R; Verma, A; Vogler, TO; Will, B; Ye, BH; Yu, Y; Zhou, L | 1 |
Ritchie, EK | 1 |
Akria, L; Arad, A; Aviv, A; Braester, A; Dally, N; Filanovsky, K; Gafter-Gvili, A; Gatt, ME; Hellmann, I; Herishanu, Y; Herzog-Tzarfati, K; Leiba, R; Merkel, D; Mittelman, M; Nagler, A; Nemets, A; Ofran, Y; Ronson, A; Rouvio, O; Silbershatz, I; Tadmor, T; Vidal, L; Yeganeh, S | 1 |
Cardoso, RS; Dias, FL; Guimarães, AP; Kronka, SN; Sakamoto-Hojo, ET | 1 |
Baker, E; Sutherland, GR | 1 |
Giles, FJ; Jabbour, EJ | 1 |
Flores-Morales, A; Johansson, B; Larsson, C; Nilsson, P; Norstedt, G; Pang, ST; Pourian, MR; Pousette, A; Weng, WH | 1 |
Hackanson, B; Lübbert, M; Robbel, C; Wijermans, P | 1 |
Bouabdallah, K; Daskalakis, M; Johansson, B; Kunzmann, R; Lübbert, M; Mauritzson, N; Müller-Berndorff, H; Onida, F; Schmitt-Gräff, A | 1 |
Nimer, SD | 1 |
Aribi, A; Cortes, J; Davisson, J; Garcia-Manero, G; Issa, JP; Jabbour, E; Kantarjian, HM; O'Brien, S; Ravandi, F; Shan, J | 1 |
Habano, W; Jiao, YF; Nakamura, S; Sugai, T | 1 |
Chronis, C; Ho, A; John, A; Khan, S; Mufti, GJ; Pomplun, S; Raj, K; Samuel, J; Thomas, NS | 1 |
Seifertová, M | 1 |
Golomb, HM; Larson, RA; Rowley, JD; Sweet, DL; Testa, JR | 1 |
Anisowicz, A; Gadi, IK; Harrison, JJ; Raffeld, M; Sager, R | 1 |
Gadi, IK; Harrison, JJ; Sager, R | 1 |
Campos, A; Fernández, JL; Gosálvez, J; Goyanes, V; Pereira, S | 1 |
Bourgeois, CA; Delattre, JY; Dutrillaux, AM; Dutrillaux, B; Kokalj-Vokac, N; Malfoy, B; Poisson, M; Vega, F | 1 |
Hagemeijer, A; Hoebee, B; Honders, MW; Landegent, JE; Stegmann, AP; Willemze, R | 1 |
Almeida, A; Dutrillaux, B; Jeanpierre, M; Kokalj-Vokac, N; Malfoy, B; Viegas-Péquignot, E | 1 |
Ehrlich, M; Frady, A; Hernandez, R; Ji, W; Qu, GZ; Varela, M; Zhang, XY | 1 |
Cortés, F; López-Baena, M; Mateos, S; Piñero, J | 1 |
Eastmond, DA; Grosovsky, AJ; Hasegawa, LS; Parks, KK; Smith, LE | 1 |
Hahn, PJ; Rizwana, R | 1 |
Sakamoto-Hojo, ET; Takahashi, CS; Takahashi-Hyodo, SA | 1 |
Hallett, WH; Vig, BK | 1 |
Camitta, B; Carroll, AJ; Chang, M; Gresik, MV; Raimondi, SC; Ravindranath, Y; Steuber, CP; Weinstein, H | 1 |
Andre, M; Bosly, A; Ferrant, A; Kunzmann, R; Lübbert, M; Ravoet, C; Verhoef, G; Wijermans, P | 1 |
Dutrillaux, B; Viegas-Péquignot, E | 1 |
Alexander, B; Berger, R; Cook, WD; Day, LM; Feneziani, A; Hogarth, PM | 1 |
Crowther, P; Davidson, S; Radley, J; Woodcock, D | 1 |
Abella, E; Alvarado, CS; Chauvenet, A; Dubowy, R; Harris, M; Inoue, S; Krischer, JP; Ravindranath, Y; Ritchey, AK; Wiley, J | 1 |
Lutze, LH; Morgan, WF; Phillips, JW; Winegar, RA | 1 |
Jenssen, D; Zhang, LH | 1 |
Ferraro, M; Lavia, P; Micheli, A; Olivieri, G | 1 |
Benedict, WF; Karon, M | 1 |
11 review(s) available for azacitidine and Abnormalities, Autosome
Article | Year |
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How and when to decide between epigenetic therapy and chemotherapy in patients with AML.
Topics: Azacitidine; Chromosome Aberrations; Decision Making; Decitabine; Epigenesis, Genetic; Humans; Leukemia, Myeloid, Acute | 2017 |
How I treat older patients with acute myeloid leukemia.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Cytarabine; Decitabine; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Histone Deacetylase Inhibitors; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Prognosis; Remission Induction; Survival Rate; Transplantation, Homologous | 2018 |
Key clinical observations after 5-azacytidine and decitabine treatment of myelodysplastic syndromes suggest practical solutions for better outcomes.
Topics: Azacitidine; Cell Proliferation; Chromosome Aberrations; Decitabine; Disease-Free Survival; DNA-Cytosine Methylases; Enzyme Inhibitors; Gene Expression Regulation; Humans; Myelodysplastic Syndromes; S Phase; Survival Rate; Transcription Factors | 2013 |
5q- syndrome-like features as the first manifestation of myelodysplastic syndrome in a patient with an unbalanced whole-arm translocation der(5;19)(p10;q10).
Topics: Anemia, Macrocytic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 19; Chromosomes, Human, Pair 5; Fatal Outcome; Female; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Thalidomide; Translocation, Genetic | 2017 |
Cytogenetic and molecular abnormalities in myelodysplastic syndrome.
Topics: Animals; Antineoplastic Agents; Azacitidine; Chromosome Aberrations; Humans; Lenalidomide; Mutation; Myelodysplastic Syndromes; Thalidomide | 2011 |
Chronic myelomonocytic leukemia: 2012 update on diagnosis, risk stratification, and management.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Examination; Chromosome Aberrations; Clinical Trials as Topic; Combined Modality Therapy; Decitabine; Diagnosis, Differential; Disease Management; Female; Genes, Neoplasm; Humans; Leukemia, Myelomonocytic, Chronic; Leukocyte Count; Male; Risk Assessment; Stem Cell Transplantation; Transplantation, Homologous | 2012 |
Safety and efficacy of azacitidine in the treatment of elderly patients with myelodysplastic syndrome.
Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Cytarabine; Disease Progression; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Outcome Assessment, Health Care; Quality of Life; Risk Assessment; Sickness Impact Profile | 2012 |
Forgotten fragile sites and related phenomena.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Bromodeoxyuridine; Chromosome Aberrations; Chromosome Fragile Sites; Cytogenetic Analysis; Humans | 2003 |
New agents in myelodysplastic syndromes.
Topics: Alkyl and Aryl Transferases; Angiogenesis Inhibitors; Apoptosis; Arsenicals; Azacitidine; Benzamides; Chromosome Aberrations; Clinical Trials as Topic; Cytokines; DNA Methylation; Enzyme Inhibitors; Farnesyltranstransferase; Growth Substances; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Immunosuppressive Agents; Myelodysplastic Syndromes; Oligonucleotides, Antisense; Piperazines; Prognosis; Pyrimidines; Treatment Outcome | 2005 |
In vivo effects of decitabine in myelodysplasia and acute myeloid leukemia: review of cytogenetic and molecular studies.
Topics: Acute Disease; Animals; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Clinical Trials as Topic; Cyclin-Dependent Kinase Inhibitor p15; Decitabine; DNA Methylation; Epigenesis, Genetic; Humans; Leukemia, Myeloid; Mice; Myelodysplastic Syndromes | 2005 |
Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q.
Topics: Anemia, Hypochromic; Azacitidine; Bone Marrow; Chromosome Aberrations; Chromosomes, Human, Pair 5; Erythrocyte Transfusion; Erythropoiesis; Erythropoietin; Gene Deletion; Hematinics; Hematopoietic Stem Cell Transplantation; Humans; Karyotyping; Lenalidomide; Myelodysplastic Syndromes; Predictive Value of Tests; Prognosis; Randomized Controlled Trials as Topic; Recombinant Proteins; Thalidomide | 2006 |
5 trial(s) available for azacitidine and Abnormalities, Autosome
Article | Year |
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Azacitidine improves outcome in higher-risk MDS patients with chromosome 7 abnormalities: a retrospective comparison of GESMD and GFM registries.
Topics: Aged; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 7; Disease-Free Survival; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Registries; Retrospective Studies; Risk Factors; Survival Rate | 2018 |
Molecular cytogenetic monitoring from CD34+ peripheral blood cells in myelodysplastic syndromes: first results from a prospective multicenter German diagnostic study.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Chromosome Banding; Female; Follow-Up Studies; Germany; Humans; In Situ Hybridization, Fluorescence; Lenalidomide; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Thalidomide; Time Factors; Treatment Outcome | 2013 |
Phase I combination trial of lenalidomide and azacitidine in patients with higher-risk myelodysplastic syndromes.
Topics: Aged; Azacitidine; Chromosome Aberrations; DNA Methylation; DNA Modification Methylases; DNA Mutational Analysis; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Karyotyping; Lenalidomide; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Precancerous Conditions; Risk Assessment; Thalidomide; Time Factors; Treatment Outcome; United States | 2010 |
Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome.
Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Decitabine; Drug Administration Schedule; Fatigue; Humans; Infusions, Intravenous; Injections, Subcutaneous; Male; Middle Aged; Multivariate Analysis; Myelodysplastic Syndromes; Prognosis; Risk Factors; Survival Analysis; Survival Rate; Treatment Outcome; Vomiting | 2007 |
CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Bone Marrow Cells; Chromosome Aberrations; Chromosomes, Human, Pair 7; Cyclin-Dependent Kinase Inhibitor p15; DNA Methylation; Female; Genetic Markers; Humans; Injections, Subcutaneous; Male; Middle Aged; Myelodysplastic Syndromes; Predictive Value of Tests; Promoter Regions, Genetic; Survival Rate; Treatment Outcome | 2007 |
56 other study(ies) available for azacitidine and Abnormalities, Autosome
Article | Year |
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[Prompt cytogenetic response by venetoclax plus azacitidine regimen in a patient with AML harboring double-minute chromosomes with MYC gene amplification].
Topics: Aged, 80 and over; Azacitidine; Chromosome Aberrations; Chromosomes; Female; Gene Amplification; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute | 2023 |
Comparative analysis of epigenetic inhibitors reveals different degrees of interference with transcriptional gene silencing and induction of DNA damage.
Topics: Adenosine; Arabidopsis; Azacitidine; Chromosome Aberrations; Cytidine; Decitabine; DNA Damage; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Silencing; Heterochromatin; RNA Interference; Tandem Repeat Sequences | 2020 |
Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognition.
Topics: ADAM17 Protein; Adult; Aged; Azacitidine; Cell Line, Tumor; Chromosome Aberrations; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Leukemic; GPI-Linked Proteins; Histocompatibility Antigens Class I; Humans; Intercellular Signaling Peptides and Proteins; Killer Cells, Natural; Leukemia, Myeloid, Acute; Male; Middle Aged; NK Cell Lectin-Like Receptor Subfamily K; Prognosis; Tissue Inhibitor of Metalloproteinase-3 | 2017 |
Impact of baseline cytogenetic findings and cytogenetic response on outcome of high-risk myelodysplastic syndromes and low blast count AML treated with azacitidine.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Female; Follow-Up Studies; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Remission Induction; Risk Factors; Survival Rate | 2017 |
5-Azacytidine treatment for relapsed or refractory acute myeloid leukemia after intensive chemotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Cells; Chromosome Aberrations; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nuclear Proteins; Nucleophosmin; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome | 2013 |
Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.
Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Chromosome Aberrations; Decitabine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Male; Middle Aged; Multiple Myeloma; Osteonectin; Phenotype; Prognosis; Transforming Growth Factor beta1; Tumor Suppressor Proteins | 2013 |
Cytogenetic response based on revised IPSS cytogenetic risk stratification and minimal residual disease monitoring by FISH in MDS patients treated with low-dose decitabine.
Topics: Abnormal Karyotype; Adult; Aged; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Cytogenetic Analysis; Decitabine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; In Situ Hybridization, Fluorescence; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm, Residual; Prognosis; Risk Assessment; Survival Rate | 2013 |
Efficacy and side-effects of decitabine in treatment of atypical chronic myeloid leukemia.
Topics: Adult; Anemia; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Decitabine; Fatal Outcome; Female; Humans; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Male; Middle Aged; Remission Induction; Thrombocytopenia; Treatment Outcome | 2015 |
Azacitidine treatment for patients with myelodysplastic syndrome and acute myeloid leukemia with chromosome 3q abnormalities.
Topics: Adult; Aged; Aged, 80 and over; Allografts; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Chromosome Aberrations; Chromosomes, Human, Pair 3; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Retrospective Studies; Stem Cell Transplantation; Survival Rate | 2015 |
Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities.
Topics: Adolescent; Adult; Azacitidine; Cell Culture Techniques; Cell Differentiation; Chromosome Aberrations; Culture Media; Female; Fibroblasts; Humans; Hydroxamic Acids; Induced Pluripotent Stem Cells; Male; Middle Aged; Neural Stem Cells; Schizophrenia; Valproic Acid; Young Adult | 2015 |
Influence of total genomic alteration and chromosomal fragmentation on response to a combination of azacitidine and lenalidomide in a cohort of patients with very high risk MDS.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Female; Humans; Kaplan-Meier Estimate; Karyotyping; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Oligonucleotide Array Sequence Analysis; Proportional Hazards Models; Thalidomide; Tumor Suppressor Protein p53 | 2015 |
Myelodysplastic syndromes following therapy with hypomethylating agents (HMAs): development of acute erythroleukemia may not influence assessment of treatment response.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biopsy; Bone Marrow; Chromosome Aberrations; Decitabine; DNA Methylation; Female; Humans; In Situ Hybridization, Fluorescence; Leukemia, Erythroblastic, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasms, Second Primary; Survival Analysis; Treatment Outcome; Young Adult | 2016 |
Epigenetic priming with decitabine followed by low-dose idarubicin/cytarabine has an increased anti-leukemic effect compared to traditional chemotherapy in high-risk myeloid neoplasms.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Cytarabine; Decitabine; Disease Progression; Drug Administration Schedule; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Recurrence; Remission Induction; Treatment Outcome | 2016 |
A new prognostic index to make short-term prognoses in MDS patients treated with azacitidine: A combination of p53 expression and cytogenetics.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Chromosome Aberrations; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Treatment Outcome; Tumor Suppressor Protein p53 | 2016 |
DNA demethylation caused by 5-Aza-2'-deoxycytidine induces mitotic alterations and aneuploidy.
Topics: Aneuploidy; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Blotting, Western; Cell Proliferation; Chromosome Aberrations; Colonic Neoplasms; Cytogenetic Analysis; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Microscopy, Fluorescence; Mitosis; Ploidies; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2016 |
Wilms Tumor 1 (WT1) mRNA Expression Level at Diagnosis Is a Significant Prognostic Marker in Elderly Patients with Myelodysplastic Syndrome.
Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers; Bone Marrow Cells; Chromosome Aberrations; Female; Gene Expression; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Research Design; Retrospective Studies; Risk Factors; RNA, Messenger; Survival Analysis; WT1 Proteins | 2017 |
TP53 mutations predict decitabine-induced complete responses in patients with myelodysplastic syndromes.
Topics: Azacitidine; Cell Transformation, Neoplastic; Chromosome Aberrations; Decitabine; Humans; Leukemia, Myeloid, Acute; Mutation; Myelodysplastic Syndromes; Predictive Value of Tests; Recurrence; Remission Induction; Survival Analysis; Treatment Outcome; Tumor Suppressor Protein p53 | 2017 |
[Predict response to decitabine in patients with myelodysplastic syndrome and related neoplasms].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 7; Decitabine; Female; Humans; Karyotype; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Neoplasms; Remission Induction; Retrospective Studies; Young Adult | 2017 |
Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 5; Decitabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Treatment Outcome | 2009 |
Effects of 5-azacytidine on lymphocyte-metaphases of Creole cows carrying the rob(1;29).
Topics: Animals; Azacitidine; Cattle; Chromosome Aberrations; Heterozygote; Karyotyping; Lymphocytes; X Chromosome | 2010 |
FISH analysis of circulating CD34+ cells as a new tool for genetic monitoring in MDS: verification of the method and application to 27 MDS patients.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD34; Azacitidine; Bone Marrow Cells; Chromosome Aberrations; Chromosomes, Human, Pair 7; Female; Humans; In Situ Hybridization, Fluorescence; Male; Middle Aged; Monosomy; Myelodysplastic Syndromes | 2010 |
Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20-methylcholanthrene.
Topics: Aneuploidy; Animals; Antimetabolites; Azacitidine; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Chromosome Aberrations; Decitabine; DNA Damage; DNA Methylation; Embryo, Mammalian; Epigenesis, Genetic; Fibroblasts; Gene Expression Regulation, Neoplastic; Genotype; Gestational Age; Methylcholanthrene; Mice; Phenotype; Phosphorylation; Signal Transduction | 2010 |
Preface. The biology and treatment of myelodysplastic syndrome.
Topics: Azacitidine; Bone Marrow Transplantation; Chromosome Aberrations; Drugs, Investigational; Epigenesis, Genetic; Humans; Mutation; Myelodysplastic Syndromes | 2010 |
Mechanisms of resistance to decitabine in the myelodysplastic syndrome.
Topics: Aged; Aged, 80 and over; Azacitidine; Chromosome Aberrations; CpG Islands; Cytidine Deaminase; Decitabine; Deoxycytidine Kinase; DNA Methylation; Drug Resistance; Female; Gene Expression Regulation; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA | 2011 |
Clonal cytogenetic abnormalities after tyrosine kinase inhibitor therapy in Ph+ ALL resolution after decitabine therapy.
Topics: Azacitidine; Benzamides; Child, Preschool; Chromosome Aberrations; Decitabine; Female; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Stem Cell Transplantation | 2012 |
Satellite 2 demethylation induced by 5-azacytidine is associated with missegregation of chromosomes 1 and 16 in human somatic cells.
Topics: Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; DNA Methylation; DNA, Satellite; Humans; Lymphocytes; Sulfites | 2012 |
Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.
Topics: Antigens, CD; Azacitidine; Case-Control Studies; Cell Lineage; Chromosome Aberrations; Chromosomes, Human, Pair 7; DNA Methylation; Epigenesis, Genetic; Flow Cytometry; Gene Expression; Hematopoietic Stem Cells; Humans; Karyotyping; Myelodysplastic Syndromes; Primary Cell Culture; Recurrence; STAT3 Transcription Factor | 2012 |
Predicting infections in high-risk patients with myelodysplastic syndrome/acute myeloid leukemia treated with azacitidine: a retrospective multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Disease Susceptibility; Female; Humans; Incidence; Infections; Israel; Leukemia, Myeloid, Acute; Male; Methylation; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Retrospective Studies; Risk Factors; Severity of Illness Index; Thrombocytopenia | 2013 |
Chromosomal aberrations induced by 5-azacytidine combined with VP-16 (etoposide) in CHO-K1 and XRS-5 cell lines.
Topics: Animals; Azacitidine; Cell Cycle; Cell Line; CHO Cells; Chromosome Aberrations; Cricetinae; Cytogenetic Analysis; Drug Combinations; Drug Interactions; Etoposide; Kinetics; Mutagens; Radiation Tolerance | 2003 |
Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer.
Topics: Androgens; Azacitidine; Cell Line, Tumor; Chromosome Aberrations; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 2; Decitabine; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Methyltransferases; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Spectral Karyotyping | 2006 |
Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia.
Topics: Aged; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 19; Cytarabine; Cytogenetic Analysis; Daunorubicin; Decitabine; Dose-Response Relationship, Drug; Fatal Outcome; Female; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Phenotype; Steroids; Treatment Outcome | 2006 |
Novel approach for detecting global epigenetic alterations associated with tumor cell aneuploidy.
Topics: Aneuploidy; Azacitidine; Cell Line, Tumor; Cell Separation; Chromosome Aberrations; CpG Islands; Cytogenetics; Diploidy; DNA Methylation; DNA Mutational Analysis; DNA-Binding Proteins; DNA, Neoplasm; HCT116 Cells; HT29 Cells; Humans; Loss of Heterozygosity; Mutation; Neoplasms; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reproducibility of Results; Transcription Factors; Zinc Fingers | 2007 |
Karyotypes of the 5-azacytidine-sensitive and -resistant line of AKR mouse leukemia.
Topics: Animals; Azacitidine; Cell Line; Cell Survival; Chromosome Aberrations; Drug Resistance; Female; Karyotyping; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mice, Inbred AKR | 1981 |
Response to 5-azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings.
Topics: Adult; Azacitidine; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Female; Follow-Up Studies; Humans; Karyotyping; Leukemia, Lymphoid; Male; Middle Aged; Translocation, Genetic | 1982 |
Azacytidine-induced tumorigenesis of CHEF/18 cells: correlated DNA methylation and chromosome changes.
Topics: Adipose Tissue; Animals; Azacitidine; Cell Line; Chromosome Aberrations; Chromosome Disorders; Cricetinae; DNA, Neoplasm; Karyotyping; Methylation; Mice; Mice, Nude; Neoplasms, Experimental; Trisomy | 1983 |
Genetic analysis of tumorigenesis: XVI. Chromosome changes in azacytidine- and insulin-induced tumorigenesis.
Topics: Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Cricetinae; Cricetulus; Embryo, Mammalian; Insulin; Karyotyping; Neoplasms, Experimental | 1984 |
An extra band within the human 9qh+ region that behaves like the surrounding constitutive heterochromatin.
Topics: 5-Methylcytosine; Adult; Azacitidine; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human; Chromosomes, Human, Pair 9; Cytosine; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Methylation; Microscopy, Electron | 1994 |
[Characterization of chromosomal rearrangements by in situ hybridization in glioblastoma].
Topics: Azacitidine; Chromosome Aberrations; Chromosome Mapping; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; DNA, Neoplasm; DNA, Satellite; Glioblastoma; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Methylation; Middle Aged; Tumor Cells, Cultured | 1994 |
In vitro-induced resistance to the deoxycytidine analogues cytarabine (AraC) and 5-aza-2'-deoxycytidine (DAC) in a rat model for acute myeloid leukemia is mediated by mutations in the deoxycytidine kinase (dck) gene.
Topics: Animals; Antineoplastic Agents; Azacitidine; Base Sequence; Chromosome Aberrations; Cytarabine; Decitabine; Deoxycytidine Kinase; Drug Resistance; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Molecular Sequence Data; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Translocation, Genetic; Tumor Cells, Cultured | 1995 |
Specific induction of uncoiling and recombination by azacytidine in classical satellite-containing constitutive heterochromatin.
Topics: Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; DNA; DNA Damage; DNA, Satellite; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Methylation; Nucleic Acid Denaturation | 1993 |
DNA demethylation and pericentromeric rearrangements of chromosome 1.
Topics: Adult; Azacitidine; B-Lymphocytes; Burkitt Lymphoma; Cell Line; Cell Line, Transformed; Centromere; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 1; Decitabine; DNA Methylation; DNA, Satellite; Face; Fibroblasts; Heterochromatin; Humans; Immunologic Deficiency Syndromes; Male; Stem Cells; Tumor Cells, Cultured | 1997 |
Enhanced sensitivity to topoisomerase inhibitors in synchronous CHO cells pre-treated with 5-azacytidine.
Topics: Amsacrine; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Azacitidine; Camptothecin; CHO Cells; Chromosome Aberrations; Cricetinae; DNA Methylation; Drug Interactions; Enzyme Inhibitors; S Phase; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1998 |
Targeted breakage of paracentromeric heterochromatin induces chromosomal instability.
Topics: 2-Aminopurine; Adenine Phosphoribosyltransferase; Azacitidine; B-Lymphocytes; Cell Line; Centromere; Chromosome Aberrations; Chromosomes, Human; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 17; DNA Damage; Heterochromatin; Humans; Hypoxanthine Phosphoribosyltransferase; In Situ Hybridization, Fluorescence; Interphase; Metaphase; Thymidine Kinase | 1998 |
CpG methylation reduces genomic instability.
Topics: Animals; Azacitidine; Cell Line; Chromosome Aberrations; CpG Islands; Dimerization; DNA Methylation; Metaphase; Mice | 1999 |
Interaction effects of 5-azacytidine with topoisomerase II inhibitors on CHO cells, as detected by cytogenetic analysis.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Cycle; CHO Cells; Chromosome Aberrations; Cricetinae; Drug Interactions; Ellipticines; Enzyme Inhibitors; Teniposide; Topoisomerase II Inhibitors | 1999 |
5-Azacytidine- and Hoechst-induced aneuploidy in Indian muntjac.
Topics: Aneuploidy; Animals; Azacitidine; Bisbenzimidazole; Cells, Cultured; Chromosome Aberrations; Karyotyping; Male; Muntjacs; Y Chromosome | 2000 |
Prognostic factors in children and adolescents with acute myeloid leukemia (excluding children with Down syndrome and acute promyelocytic leukemia): univariate and recursive partitioning analysis of patients treated on Pediatric Oncology Group (POG) Study
Topics: Adolescent; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cohort Studies; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Life Tables; Male; Multicenter Studies as Topic; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Remission Induction; Risk Assessment; Risk Factors; Survival Analysis; Thioguanine; Translocation, Genetic; Treatment Failure; Treatment Outcome; United States | 2000 |
Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sideroblastic; Antimetabolites, Antineoplastic; Azacitidine; Chromosome Aberrations; Chromosome Disorders; Decitabine; Drug Administration Schedule; Female; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Risk; Survival Rate | 2001 |
Segmentation of human chromosomes induced by 5-ACR (5-azacytidine).
Topics: Azacitidine; Azure Stains; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Chromosomes; Humans; Lymphocytes; Staining and Labeling | 1976 |
Tumor-associated karyotypic lesions coselected with in vitro macrophage differentiation.
Topics: Abelson murine leukemia virus; Animals; Azacitidine; Biomarkers, Tumor; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cell Transformation, Viral; Chromosome Aberrations; Dexamethasone; Hematopoietic Stem Cells; Hydroxyurea; Karyotyping; Leukemia, Experimental; Macrophages; Mice; Selection, Genetic; Thymus Neoplasms; Tumor Cells, Cultured | 1992 |
Cytotoxicity of 5-aza-2'-deoxycytidine in a mammalian cell system.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Decitabine; DNA; Female; Methylation; Ovary | 1992 |
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azacitidine; Child; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine | 1992 |
Chromosome aberration induction in Chinese hamster ovary cells by restriction enzymes with different methylation sensitivity.
Topics: Animals; Azacitidine; Cell Line; Chromosome Aberrations; Cricetinae; Cytosine; Decitabine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Methylation; Substrate Specificity | 1990 |
Isolation and characterization of spontaneously occurring mutations at the HPRT locus in V79 Chinese hamster cells.
Topics: Animals; Azacitidine; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Ethyl Methanesulfonate; Ethylnitrosourea; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Mutation; Sodium-Potassium-Exchanging ATPase | 1989 |
Effect of 5-azacytidine (5-azaC) on the induction of chromatid aberrations (CA) and sister-chromatid exchanges (SCE).
Topics: Azacitidine; Cells, Cultured; Chromatids; Chromosome Aberrations; Drug Synergism; Humans; Lymphocytes; Male; Mitomycin; Mitomycins; Sister Chromatid Exchange; X-Rays | 1985 |
Chromatid breakage: differential effect of inhibitors of DNA synthesis during G 2 phase.
Topics: Animals; Azacitidine; Azaguanine; Cell Line; Chromatids; Chromosome Aberrations; Cricetinae; Cytarabine; Cytidine; DNA; DNA Nucleotidyltransferases; Hydroxyurea; Lung; Mitosis; Oxidoreductases; Pyridines; Ribonucleotides; Thiosemicarbazones; Triazines | 1972 |