avermectin-b(1)a and Tick-Infestations

avermectin-b(1)a has been researched along with Tick-Infestations* in 4 studies

Reviews

2 review(s) available for avermectin-b(1)a and Tick-Infestations

Article	Year
Perspectives in animal health: old targets and new opportunities. Journal of medicinal chemistry, 2001, Mar-01, Volume: 44, Issue:5 Topics: Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Anti-Ulcer Agents; Antiparasitic Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Forecasting; Horse Diseases; Horses; Siphonaptera; Tick Infestations; Veterinary Drugs	2001
The avermectins: A new family of antiparasitic agents. Journal of the South African Veterinary Association, 1982, Volume: 53, Issue:2 The avermectins are macrocyclic lactones produced by fermentation of the soil micro-organism Streptomyces avermitilis. They show activity against a broad range of nematodes and arthropod parasites of domestic animals at dose rates of 300 microgram/kg or less. Unlike the macrolide or polyene antibiotics, they lack significant antibacterial or antifungal activity. By oral or parenteral administration, avermectins are active against gastrointestinal nematodes and lungworms, and important ectoparasites such as lice, mange mites, ticks and larval stages of flies. They show excellent activity against parasites resistant to existing anthelmintics or ectoparasiticides. The avermectins appear to cause paralysis of nematodes and arthropods by opening gamma-aminobutyric acid-mediated chloride channels at the neuromuscular junction. Topics: Animals; Anoplura; Anthelmintics; Antinematodal Agents; Cattle; Cattle Diseases; Dog Diseases; Dogs; Horse Diseases; Horses; Ivermectin; Lactones; Mite Infestations; Nematode Infections; Sheep; Sheep Diseases; Swine; Swine Diseases; Tick Infestations	1982

Article

Year

Perspectives in animal health: old targets and new opportunities.

Journal of medicinal chemistry, 2001, Mar-01, Volume: 44, Issue:5

Topics: Animals; Anthelmintics; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Anti-Ulcer Agents; Antiparasitic Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Forecasting; Horse Diseases; Horses; Siphonaptera; Tick Infestations; Veterinary Drugs

2001

The avermectins: A new family of antiparasitic agents.

Journal of the South African Veterinary Association, 1982, Volume: 53, Issue:2

The avermectins are macrocyclic lactones produced by fermentation of the soil micro-organism Streptomyces avermitilis. They show activity against a broad range of nematodes and arthropod parasites of domestic animals at dose rates of 300 microgram/kg or less. Unlike the macrolide or polyene antibiotics, they lack significant antibacterial or antifungal activity. By oral or parenteral administration, avermectins are active against gastrointestinal nematodes and lungworms, and important ectoparasites such as lice, mange mites, ticks and larval stages of flies. They show excellent activity against parasites resistant to existing anthelmintics or ectoparasiticides. The avermectins appear to cause paralysis of nematodes and arthropods by opening gamma-aminobutyric acid-mediated chloride channels at the neuromuscular junction.

Topics: Animals; Anoplura; Anthelmintics; Antinematodal Agents; Cattle; Cattle Diseases; Dog Diseases; Dogs; Horse Diseases; Horses; Ivermectin; Lactones; Mite Infestations; Nematode Infections; Sheep; Sheep Diseases; Swine; Swine Diseases; Tick Infestations

1982

Other Studies

2 other study(ies) available for avermectin-b(1)a and Tick-Infestations

Article	Year
Polyfluoro 1,3-diketones as systemic insecticides. Journal of medicinal chemistry, 1989, Volume: 32, Issue:9 A series of aryl polyfluoro 1,3-diketones were examined for systemic ectoparasiticidal activity in cattle. The compounds demonstrated efficacy against several economically important species of insects and acarina. At dosages of 5 mg/kg X1 or 0.35 mg/kg per day intraruminally, activity was observed against blowfly larvae (Phormia regina), adult stable fly (Stomoxys calcitrans), and lone star tick (Amblyomma americanum). In vivo activity was not directly related to in vitro activity, showing a stronger dependence on perfluoroalkyl-chain length and aryl-group substitution. Topics: Animals; Cattle; Diptera; Dose-Response Relationship, Drug; Ectoparasitic Infestations; Hydrocarbons, Fluorinated; Insecticides; Ketones; Larva; Tick Infestations	1989
Control of ticks systemically with Merck MK-933, an avermectin. Journal of economic entomology, 1981, Volume: 74, Issue:4 Topics: Animals; Cattle; Cattle Diseases; Ivermectin; Lactones; Tick Infestations	1981

Article

Year

Polyfluoro 1,3-diketones as systemic insecticides.

Journal of medicinal chemistry, 1989, Volume: 32, Issue:9

A series of aryl polyfluoro 1,3-diketones were examined for systemic ectoparasiticidal activity in cattle. The compounds demonstrated efficacy against several economically important species of insects and acarina. At dosages of 5 mg/kg X1 or 0.35 mg/kg per day intraruminally, activity was observed against blowfly larvae (Phormia regina), adult stable fly (Stomoxys calcitrans), and lone star tick (Amblyomma americanum). In vivo activity was not directly related to in vitro activity, showing a stronger dependence on perfluoroalkyl-chain length and aryl-group substitution.

Topics: Animals; Cattle; Diptera; Dose-Response Relationship, Drug; Ectoparasitic Infestations; Hydrocarbons, Fluorinated; Insecticides; Ketones; Larva; Tick Infestations

1989

Control of ticks systemically with Merck MK-933, an avermectin.

Journal of economic entomology, 1981, Volume: 74, Issue:4

Topics: Animals; Cattle; Cattle Diseases; Ivermectin; Lactones; Tick Infestations

1981