avasimibe has been researched along with Disease Models, Animal in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Chen, X; Song, Q; Xia, L; Xu, X | 1 |
| Bowen, ZD; Bryleva, EY; Chang, CCY; Chang, TY; Harris, BT; Kheirollah, A; Murphy, SR; Niu, Z; Shibuya, Y | 1 |
| Barren, C; Duller, S; Frosch, MP; Havas, D; Hutter-Paier, B; Huttunen, HJ; Kovacs, DM; Peach, C; Windisch, M; Xia, W | 1 |
| Miyazaki, A; Watanabe, T | 1 |
| Krause, BR; Nicolosi, RJ; Wilson, TA | 1 |
| de Wit, EC; Delsing, DJ; Gijbels, MJ; Havekes, LM; Jukema, JW; Offerman, EH; Princen, HM; van Der Boom, H; van Der Laarse, A; van Duyvenvoorde, W | 1 |
1 review(s) available for avasimibe and Disease Models, Animal
| Article | Year |
|---|---|
[Acyl-coenzyme A: cholesterol acyltransferase (ACAT)].
Topics: Acetamides; Acetates; Adiponectin; Animals; Arteriosclerosis; Cholesterol Esters; Disease Models, Animal; Drug Design; Foam Cells; Humans; Intercellular Signaling Peptides and Proteins; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Sulfonamides; Sulfonic Acids | 2004 |
6 other study(ies) available for avasimibe and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Synergy of Dendritic Cell Vaccines and Avasimibe in Treatment of Head and Neck Cancer in Mice.
Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Animals; Cancer Vaccines; Carcinoma, Squamous Cell; Cell Line, Tumor; Combined Modality Therapy; Dendritic Cells; Disease Models, Animal; Female; Head and Neck Neoplasms; Immunotherapy; Mice; Mice, Inbred C3H; Neoplasm Recurrence, Local; Squamous Cell Carcinoma of Head and Neck; Sulfonamides; Sulfonic Acids; T-Lymphocytes; Vaccines | 2017 |
Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.
Topics: Acetamides; Acetates; Acetyl-CoA C-Acetyltransferase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autophagy; Benzimidazoles; Brain; Cells, Cultured; Cholesterol; Cholesterol Esters; Disease Models, Animal; Enzyme Inhibitors; Gene Knockdown Techniques; Mice, Inbred C57BL; Mice, Transgenic; Molecular Targeted Therapy; Neurons; Peptide Fragments; Presenilin-1; Sulfonamides; Sulfonic Acids; tau Proteins | 2015 |
The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice.
Topics: Acetamides; Acetates; Aging; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apolipoproteins E; Brain; Cholesterol; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gliosis; Humans; Image Processing, Computer-Assisted; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Peptide Fragments; Presenilin-1; Pyridines; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids | 2010 |
The ACAT inhibitor, CI-1011 is effective in the prevention and regression of aortic fatty streak area in hamsters.
Topics: Acetamides; Acetates; Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cricetinae; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Liver; Male; Reference Values; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids; Time Factors; Triglycerides | 1998 |
Acyl-CoA:cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice.
Topics: Acetamides; Acetates; Animals; Anticholesteremic Agents; Aortic Valve; Apolipoprotein E3; Apolipoproteins E; Arteriosclerosis; Body Weight; Cell Adhesion; Cell Line; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Eating; Endothelium, Vascular; Female; Heterozygote; Lipoproteins; Macrophages; Mice; Mice, Transgenic; Sterol O-Acyltransferase; Sulfonamides; Sulfonic Acids | 2001 |