avapro has been researched along with Pregnancy in 6 studies
Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Angiotensin converting enzyme (ACE) inhibitors and angiotensin II (AT-II)-receptor-antagonists have been demonstrated to cause fetotoxicity when administered to women during the second and third trimester of pregnancy." | 7.73 | Teratogenicity with angiotensin II receptor antagonists in pregnancy. ( Boix, E; Moreno, O; Picó, A; Zapater, P, 2005) |
| "Angiotensin converting enzyme (ACE) inhibitors and angiotensin II (AT-II)-receptor-antagonists have been demonstrated to cause fetotoxicity when administered to women during the second and third trimester of pregnancy." | 3.73 | Teratogenicity with angiotensin II receptor antagonists in pregnancy. ( Boix, E; Moreno, O; Picó, A; Zapater, P, 2005) |
| "Duration of treatment during pregnancy among women who had adverse fetal outcomes was 26." | 2.44 | Angiotensin II receptor blockers in pregnancy: a case report and systematic review of the literature. ( Choi, JS; Han, JY; Nava-Ocampo, AA; Velázquez-Armenta, EY; Yang, KM, 2007) |
| "Recent studies have shown that preeclampsia (PE) is associated with the presence of autoantibodies (AABs) that activate the angiotensin II AT1 receptor, which could contribute to many of the symptoms of PE." | 1.43 | Identification of a Novel Agonist-Like Autoantibody in Preeclamptic Patients. ( Bader, M; Braga, JF; Cabral, AC; Pimentel, RL; Reis, ZS; Santos, RA; Velloso, EP; Wallukat, G, 2016) |
| " The oral bioavailability in macaques was notably higher than in rats." | 1.31 | Disposition of irbesartan, an angiotensin II AT1-receptor antagonist, in mice, rats, rabbits, and macaques. ( Berger, Y; Caix, J; Davi, H; DuPont, P; Miscoria, G; Perrier, L; Simiand, J; Tronquet, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Velloso, EP | 1 |
| Pimentel, RL | 1 |
| Braga, JF | 1 |
| Cabral, AC | 1 |
| Reis, ZS | 1 |
| Bader, M | 1 |
| Santos, RA | 1 |
| Wallukat, G | 1 |
| Gersak, K | 1 |
| Cvijic, M | 1 |
| Cerar, LK | 1 |
| Boix, E | 1 |
| Zapater, P | 1 |
| Picó, A | 1 |
| Moreno, O | 1 |
| Velázquez-Armenta, EY | 1 |
| Han, JY | 1 |
| Choi, JS | 1 |
| Yang, KM | 1 |
| Nava-Ocampo, AA | 1 |
| Davi, H | 1 |
| Tronquet, C | 1 |
| Miscoria, G | 1 |
| Perrier, L | 1 |
| DuPont, P | 1 |
| Caix, J | 1 |
| Simiand, J | 1 |
| Berger, Y | 1 |
| Peers, A | 1 |
| Campbell, DJ | 1 |
| Wintour, EM | 1 |
| Dodic, M | 1 |
1 review available for avapro and Pregnancy
| Article | Year |
|---|---|
Angiotensin II receptor blockers in pregnancy: a case report and systematic review of the literature.
Topics: Abortion, Spontaneous; Adult; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Female; H | 2007 |
5 other studies available for avapro and Pregnancy
| Article | Year |
|---|---|
Identification of a Novel Agonist-Like Autoantibody in Preeclamptic Patients.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Animals; Autoantibodies; Biphenyl Compounds; Case-Co | 2016 |
Angiotensin II receptor blockers in pregnancy: a report of five cases.
Topics: Abnormalities, Drug-Induced; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphe | 2009 |
Teratogenicity with angiotensin II receptor antagonists in pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Bipheny | 2005 |
Disposition of irbesartan, an angiotensin II AT1-receptor antagonist, in mice, rats, rabbits, and macaques.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Ag | 2000 |
The peripheral renin-angiotensin system is not involved in the hypertension of sheep exposed to prenatal dexamethasone.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antihypertensive Agents; | 2001 |