avapro and Hypertrophy
avapro has been researched along with Hypertrophy in 7 studies
Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cellular hypertrophy is an early, important pathological feature of renal diseases such as diabetic nephropathy and remnant kidney." | 5.33 | Connective tissue growth factor-mediated angiotensin II-induced hypertrophy of proximal tubular cells. ( Chen, L; Huang, HQ; Liu, BC; Liu, DG; Liu, H; Ma, KL; Sun, J; Zhang, XL, 2006) |
| "For a given decrease in blood pressure, aliskiren improves coronary endothelial function and decreases cardiac hypertrophy in SHR to at least the same degree as ACE inhibition and AT1 receptor blockade." | 3.76 | Beneficial cardiac effects of the renin inhibitor aliskiren in spontaneously hypertensive rats. ( Bouhuizen, AM; Danser, AH; Garrelds, IM; Leijten, F; Moltzer, E; van Esch, JH; van Veghel, R, 2010) |
| "Cellular hypertrophy is an early, important pathological feature of renal diseases such as diabetic nephropathy and remnant kidney." | 1.33 | Connective tissue growth factor-mediated angiotensin II-induced hypertrophy of proximal tubular cells. ( Chen, L; Huang, HQ; Liu, BC; Liu, DG; Liu, H; Ma, KL; Sun, J; Zhang, XL, 2006) |
| "Post-MI hypertrophy was associated with substantial increases in the messenger RNA (mRNA) expression of atrial natriuretic peptide (ANP), but no significant changes in SERCA or PLB levels." | 1.30 | Angiotensin type 1 receptor antagonism with irbesartan inhibits ventricular hypertrophy and improves diastolic function in the remodeling post-myocardial infarction ventricle. ( Ambrose, J; Giraud, GD; Greenberg, BH; Muldoon, L; Perkins, KD; Pribnow, DG, 1999) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Sakuta, T | 1 |
| Morita, Y | 1 |
| Satoh, M | 1 |
| Fox, DA | 1 |
| Kashihara, N | 1 |
| van Esch, JH | 1 |
| Moltzer, E | 1 |
| van Veghel, R | 1 |
| Garrelds, IM | 1 |
| Leijten, F | 1 |
| Bouhuizen, AM | 1 |
| Danser, AH | 1 |
| Liu, BC | 4 |
| Luo, DD | 2 |
| Sun, J | 3 |
| Ma, KL | 4 |
| Ruan, XZ | 2 |
| Chen, Q | 1 |
| Xu, Y | 1 |
| Huang, HQ | 2 |
| Yin, LF | 1 |
| Liu, DG | 2 |
| Chen, L | 1 |
| Liu, H | 1 |
| Zhang, XL | 1 |
| Ambrose, J | 1 |
| Pribnow, DG | 1 |
| Giraud, GD | 1 |
| Perkins, KD | 1 |
| Muldoon, L | 1 |
| Greenberg, BH | 1 |
Other Studies
7 other studies available for avapro and Hypertrophy
| Article | Year |
|---|---|
Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Arthritis, Experi | 2010 |
Beneficial cardiac effects of the renin inhibitor aliskiren in spontaneously hypertensive rats.
Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotens | 2010 |
[Influence of irbesartan on renal hypertrophy and thickening of glomerular basement-membrane in streptozotocin-induced diabetic rats].
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Basement Membrane; Biphenyl Compounds; Diabetes Me | 2003 |
Effect of irbesartan on angiotensin II-induced hypertrophy of human proximal tubular cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cell Cycle; Cells, Cult | 2004 |
Effects of irbesartan on the expression of matrix metalloproteinase-2/tissue inhibitor of metalloproteinase-2 in streptozotocin-induced diabetic rat kidney.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Creatinine; Diabetes Mellitus, | 2005 |
Connective tissue growth factor-mediated angiotensin II-induced hypertrophy of proximal tubular cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Cell Cycle; Ce | 2006 |
Angiotensin type 1 receptor antagonism with irbesartan inhibits ventricular hypertrophy and improves diastolic function in the remodeling post-myocardial infarction ventricle.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Biphe | 1999 |