avapro has been researched along with Colorectal Neoplasms in 4 studies
Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to investigate the effect of an ACE-I (captopril) and an AT1R antagonist (irbesartan) in colorectal cancer liver metastases." | 3.74 | Effect of ACE inhibitors and angiotensin II receptor antagonists in a mouse model of colorectal cancer liver metastases. ( Christophi, C; Malcontenti-Wilson, C; Muralidharan, V; Neo, JH, 2007) |
| "Colorectal cancers are one of the most prevalent tumour types worldwide and, despite the emergence of targeted and biologic therapies, have among the highest mortality rates." | 1.91 | Immune Activation following Irbesartan Treatment in a Colorectal Cancer Patient: A Case Study. ( Brown, SD; Corbett, RD; Holt, RA; Jones, MR; Jones, SJM; Kalloger, S; Laskin, J; Lim, HJ; Marra, MA; Milne, K; Mungall, AJ; Mungall, K; Nelson, BH; Ng, T; Schaeffer, DF; Titmuss, E; Topham, JT; Williamson, LM; Wilson, D, 2023) |
| "A patient suffering from metastatic colorectal cancer, treatment-related toxicity and resistance to standard chemotherapy and radiation was assessed as part of a personalized oncogenomics initiative to derive potential alternative therapeutic strategies." | 1.43 | Response to angiotensin blockade with irbesartan in a patient with metastatic colorectal cancer. ( Ch'ng, C; Dar, N; Jones, MR; Jones, SJ; Laskin, J; Lim, HJ; Ma, Y; Marra, MA; Moore, R; Mungall, AJ; Ng, T; Pleasance, E; Renouf, DJ; Schein, JE; Schrader, KA; Sheffield, BS; Shen, Y; Yip, S; Zhao, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Titmuss, E | 1 |
| Milne, K | 1 |
| Jones, MR | 2 |
| Ng, T | 2 |
| Topham, JT | 1 |
| Brown, SD | 1 |
| Schaeffer, DF | 1 |
| Kalloger, S | 1 |
| Wilson, D | 1 |
| Corbett, RD | 1 |
| Williamson, LM | 1 |
| Mungall, K | 1 |
| Mungall, AJ | 2 |
| Holt, RA | 1 |
| Nelson, BH | 1 |
| Jones, SJM | 1 |
| Laskin, J | 2 |
| Lim, HJ | 2 |
| Marra, MA | 2 |
| Schrader, KA | 1 |
| Shen, Y | 1 |
| Pleasance, E | 1 |
| Ch'ng, C | 1 |
| Dar, N | 1 |
| Yip, S | 1 |
| Renouf, DJ | 1 |
| Schein, JE | 1 |
| Zhao, Y | 1 |
| Moore, R | 1 |
| Ma, Y | 1 |
| Sheffield, BS | 1 |
| Jones, SJ | 1 |
| Ager, EI | 1 |
| Wen, SW | 1 |
| Chan, J | 1 |
| Chong, WW | 1 |
| Neo, JH | 2 |
| Christophi, C | 2 |
| Malcontenti-Wilson, C | 1 |
| Muralidharan, V | 1 |
4 other studies available for avapro and Colorectal Neoplasms
| Article | Year |
|---|---|
Immune Activation following Irbesartan Treatment in a Colorectal Cancer Patient: A Case Study.
Topics: Antihypertensive Agents; CD8-Positive T-Lymphocytes; Colorectal Neoplasms; Humans; Irbesartan | 2023 |
Response to angiotensin blockade with irbesartan in a patient with metastatic colorectal cancer.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensins; Biphenyl Compounds; Colorectal Neoplasms; Comp | 2016 |
Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation.
Topics: Adenocarcinoma; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzym | 2011 |
Effect of ACE inhibitors and angiotensin II receptor antagonists in a mouse model of colorectal cancer liver metastases.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl | 2007 |