avapro has been researched along with Carotid Stenosis in 3 studies
Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy patients with symptomatic carotid artery stenosis were randomized to irbesartan (300 mg/d) or chlorthalidone (50 mg/d) for 4 months before endarterectomy." | 2.71 | Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity. ( Bei, R; Bucci, M; Cipollone, F; Cuccurullo, C; Cuccurullo, F; de Cesare, D; De Luca, M; Fazia, M; Iezzi, A; Mezzetti, A; Muraro, R; Pini, B; Spigonardo, F; Ucchino, S; Zucchelli, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, CH | 1 |
| Yu, SM | 1 |
| Lau, SC | 1 |
| Chen, YL | 1 |
| Pei, D | 1 |
| Liu, IC | 1 |
| Cipollone, F | 1 |
| Fazia, M | 1 |
| Iezzi, A | 1 |
| Pini, B | 1 |
| Cuccurullo, C | 1 |
| Zucchelli, M | 1 |
| de Cesare, D | 1 |
| Ucchino, S | 1 |
| Spigonardo, F | 1 |
| De Luca, M | 1 |
| Muraro, R | 1 |
| Bei, R | 1 |
| Bucci, M | 1 |
| Cuccurullo, F | 1 |
| Mezzetti, A | 1 |
| Golledge, J | 1 |
| McCann, M | 1 |
| Mangan, S | 1 |
| Lam, A | 1 |
| Karan, M | 1 |
1 trial available for avapro and Carotid Stenosis
| Article | Year |
|---|---|
Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agent | 2004 |
2 other studies available for avapro and Carotid Stenosis
| Article | Year |
|---|---|
Restless legs syndrome/Willis-Ekbom disease in type 2 diabetes as the initial manifestation of Parkinson's disease and major cardiovascular disease.
Topics: Aged; Amines; Analgesics; Anticonvulsants; Antihypertensive Agents; Antiparkinson Agents; Aspirin; B | 2017 |
Osteoprotegerin and osteopontin are expressed at high concentrations within symptomatic carotid atherosclerosis.
Topics: Aged; Angiotensin II; Arteriosclerosis; Biphenyl Compounds; Blotting, Western; Carotid Stenosis; Car | 2004 |