avapro has been researched along with Brain Ischemia in 5 studies
Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether 30 days of treatment with atorvastatin, or irbesartan, initiated within 96 h of symptom onset improves recovery from acute ischemic stroke." | 9.16 | A randomized placebo controlled trial of early treatment of acute ischemic stroke with atorvastatin and irbesartan. ( Beer, C; Blacker, D; Bynevelt, M; Hankey, GJ; Puddey, IB, 2012) |
| "Focal cerebral ischemia was induced by MCA occlusion for 2 hours followed by reperfusion for 22 hours." | 5.37 | Protective effect of irbesartan, an angiotensin II receptor antagonist, alone and in combination with aspirin on middle cerebral artery occlusion model of focal cerebral ischemia in rats. ( Ahmad, SJ; Akhtar, M; Islam, F; Khanam, R; Pillai, KK; Pratap, R, 2011) |
| "To determine whether 30 days of treatment with atorvastatin, or irbesartan, initiated within 96 h of symptom onset improves recovery from acute ischemic stroke." | 5.16 | A randomized placebo controlled trial of early treatment of acute ischemic stroke with atorvastatin and irbesartan. ( Beer, C; Blacker, D; Bynevelt, M; Hankey, GJ; Puddey, IB, 2012) |
| "Focal cerebral ischemia was induced by MCA occlusion for 2 hours followed by reperfusion for 22 hours." | 1.37 | Protective effect of irbesartan, an angiotensin II receptor antagonist, alone and in combination with aspirin on middle cerebral artery occlusion model of focal cerebral ischemia in rats. ( Ahmad, SJ; Akhtar, M; Islam, F; Khanam, R; Pillai, KK; Pratap, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Culman, J | 2 |
| Jacob, T | 1 |
| Schuster, SO | 1 |
| Brolund-Spaether, K | 1 |
| Brolund, L | 1 |
| Cascorbi, I | 1 |
| Zhao, Y | 2 |
| Gohlke, P | 2 |
| Pratap, R | 1 |
| Pillai, KK | 1 |
| Khanam, R | 1 |
| Islam, F | 1 |
| Ahmad, SJ | 1 |
| Akhtar, M | 1 |
| Tsukuda, K | 1 |
| Mogi, M | 1 |
| Iwanami, J | 1 |
| Min, LJ | 1 |
| Jing, F | 1 |
| Oshima, K | 1 |
| Horiuchi, M | 1 |
| Beer, C | 1 |
| Blacker, D | 1 |
| Bynevelt, M | 1 |
| Hankey, GJ | 1 |
| Puddey, IB | 1 |
| Lou, M | 1 |
| Blume, A | 1 |
| Deuschl, G | 1 |
| Herdegen, T | 1 |
1 trial available for avapro and Brain Ischemia
| Article | Year |
|---|---|
A randomized placebo controlled trial of early treatment of acute ischemic stroke with atorvastatin and irbesartan.
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Biphenyl Compounds; | 2012 |
4 other studies available for avapro and Brain Ischemia
| Article | Year |
|---|---|
Neuroprotective effects of AT1 receptor antagonists after experimental ischemic stroke: what is important?
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl | 2017 |
Protective effect of irbesartan, an angiotensin II receptor antagonist, alone and in combination with aspirin on middle cerebral artery occlusion model of focal cerebral ischemia in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aspirin; Biphenyl Compounds; Brain I | 2011 |
Irbesartan attenuates ischemic brain damage by inhibition of MCP-1/CCR2 signaling pathway beyond AT₁ receptor blockade.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Brain Ischemia; Germanium; Irb | 2011 |
Sustained blockade of brain AT1 receptors before and after focal cerebral ischemia alleviates neurologic deficits and reduces neuronal injury, apoptosis, and inflammatory responses in the rat.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Biphenyl Compounds; Brain; Brain Ischem | 2004 |