Page last updated: 2024-10-29

avapro and Brain Ischemia

avapro has been researched along with Brain Ischemia in 5 studies

Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"To determine whether 30 days of treatment with atorvastatin, or irbesartan, initiated within 96 h of symptom onset improves recovery from acute ischemic stroke."9.16A randomized placebo controlled trial of early treatment of acute ischemic stroke with atorvastatin and irbesartan. ( Beer, C; Blacker, D; Bynevelt, M; Hankey, GJ; Puddey, IB, 2012)
"Focal cerebral ischemia was induced by MCA occlusion for 2 hours followed by reperfusion for 22 hours."5.37Protective effect of irbesartan, an angiotensin II receptor antagonist, alone and in combination with aspirin on middle cerebral artery occlusion model of focal cerebral ischemia in rats. ( Ahmad, SJ; Akhtar, M; Islam, F; Khanam, R; Pillai, KK; Pratap, R, 2011)
"To determine whether 30 days of treatment with atorvastatin, or irbesartan, initiated within 96 h of symptom onset improves recovery from acute ischemic stroke."5.16A randomized placebo controlled trial of early treatment of acute ischemic stroke with atorvastatin and irbesartan. ( Beer, C; Blacker, D; Bynevelt, M; Hankey, GJ; Puddey, IB, 2012)
"Focal cerebral ischemia was induced by MCA occlusion for 2 hours followed by reperfusion for 22 hours."1.37Protective effect of irbesartan, an angiotensin II receptor antagonist, alone and in combination with aspirin on middle cerebral artery occlusion model of focal cerebral ischemia in rats. ( Ahmad, SJ; Akhtar, M; Islam, F; Khanam, R; Pillai, KK; Pratap, R, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Culman, J2
Jacob, T1
Schuster, SO1
Brolund-Spaether, K1
Brolund, L1
Cascorbi, I1
Zhao, Y2
Gohlke, P2
Pratap, R1
Pillai, KK1
Khanam, R1
Islam, F1
Ahmad, SJ1
Akhtar, M1
Tsukuda, K1
Mogi, M1
Iwanami, J1
Min, LJ1
Jing, F1
Oshima, K1
Horiuchi, M1
Beer, C1
Blacker, D1
Bynevelt, M1
Hankey, GJ1
Puddey, IB1
Lou, M1
Blume, A1
Deuschl, G1
Herdegen, T1

Trials

1 trial available for avapro and Brain Ischemia

ArticleYear
A randomized placebo controlled trial of early treatment of acute ischemic stroke with atorvastatin and irbesartan.
    International journal of stroke : official journal of the International Stroke Society, 2012, Volume: 7, Issue:2

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Biphenyl Compounds;

2012

Other Studies

4 other studies available for avapro and Brain Ischemia

ArticleYear
Neuroprotective effects of AT1 receptor antagonists after experimental ischemic stroke: what is important?
    Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl

2017
Protective effect of irbesartan, an angiotensin II receptor antagonist, alone and in combination with aspirin on middle cerebral artery occlusion model of focal cerebral ischemia in rats.
    Human & experimental toxicology, 2011, Volume: 30, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aspirin; Biphenyl Compounds; Brain I

2011
Irbesartan attenuates ischemic brain damage by inhibition of MCP-1/CCR2 signaling pathway beyond AT₁ receptor blockade.
    Biochemical and biophysical research communications, 2011, Jun-03, Volume: 409, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Brain Ischemia; Germanium; Irb

2011
Sustained blockade of brain AT1 receptors before and after focal cerebral ischemia alleviates neurologic deficits and reduces neuronal injury, apoptosis, and inflammatory responses in the rat.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2004, Volume: 24, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Biphenyl Compounds; Brain; Brain Ischem

2004