avapro and Atheroma
avapro has been researched along with Atheroma in 5 studies
Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our findings suggest that ATR1 blockade alters AII, MMP-1, MMP-8 expression and a marker of elastin degradation in human atheroma, but that the elastin degradation response is not MMP driven." | 7.79 | Role of the angiotensin converting enzyme 1/angiotensin II/angiotensin receptor 1 axis in interstitial collagenase expression in human carotid atheroma. ( Clancy, P; Golledge, J; Koblar, SA; Seto, SW, 2013) |
| "Our findings suggest that ATR1 blockade alters AII, MMP-1, MMP-8 expression and a marker of elastin degradation in human atheroma, but that the elastin degradation response is not MMP driven." | 3.79 | Role of the angiotensin converting enzyme 1/angiotensin II/angiotensin receptor 1 axis in interstitial collagenase expression in human carotid atheroma. ( Clancy, P; Golledge, J; Koblar, SA; Seto, SW, 2013) |
| "The reduction in cytokine levels in the atheroma supernatant was correlated to a reduction in ERK1/2 expression in the tissue." | 1.40 | Angiotensin receptor 1 blockade reduces secretion of inflammation associated cytokines from cultured human carotid atheroma and vascular cells in association with reduced extracellular signal regulated kinase expression and activation. ( Clancy, P; Golledge, J; Koblar, SA, 2014) |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Li, S | 1 |
| Wang, K | 1 |
| Xu, G | 1 |
| Ji, J | 1 |
| Qin, C | 1 |
| Li, L | 1 |
| Li, J | 1 |
| Yi, J | 1 |
| Liu, H | 1 |
| Lei, H | 1 |
| Clancy, P | 2 |
| Seto, SW | 1 |
| Koblar, SA | 2 |
| Golledge, J | 2 |
| Zhao, Y | 1 |
| Watanabe, A | 1 |
| Zhao, S | 1 |
| Kobayashi, T | 1 |
| Fukao, K | 1 |
| Tanaka, Y | 1 |
| Nakano, T | 1 |
| Yoshida, T | 1 |
| Takemoto, H | 1 |
| Tamaki, N | 1 |
| Kuge, Y | 1 |
Other Studies
5 other studies available for avapro and Atheroma
| Article | Year |
|---|---|
The intervention effect of zinc supplementation on irbesartan treatment for atherosclerosis of ApoE-/- mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Aor | 2016 |
Dose-Effect of Irbesartan on Cyclooxygenase-2 and Matrix Metalloproteinase-9 Expression in Rabbit Atherosclerosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Aortic Diseases; Atheroscle | 2018 |
Role of the angiotensin converting enzyme 1/angiotensin II/angiotensin receptor 1 axis in interstitial collagenase expression in human carotid atheroma.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; B | 2013 |
Suppressive effects of irbesartan on inflammation and apoptosis in atherosclerotic plaques of apoE-/- mice: molecular imaging with 14C-FDG and 99mTc-annexin A5.
Topics: Analysis of Variance; Animals; Annexin A5; Apolipoproteins E; Apoptosis; Autoradiography; Azo Compou | 2014 |
Angiotensin receptor 1 blockade reduces secretion of inflammation associated cytokines from cultured human carotid atheroma and vascular cells in association with reduced extracellular signal regulated kinase expression and activation.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aged; Angiotensin II Type 1 Receptor Blockers; Biphenyl Com | 2014 |