Page last updated: 2024-10-29

avapro and Atheroma

avapro has been researched along with Atheroma in 5 studies

Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

Research Excerpts

ExcerptRelevanceReference
"Our findings suggest that ATR1 blockade alters AII, MMP-1, MMP-8 expression and a marker of elastin degradation in human atheroma, but that the elastin degradation response is not MMP driven."7.79Role of the angiotensin converting enzyme 1/angiotensin II/angiotensin receptor 1 axis in interstitial collagenase expression in human carotid atheroma. ( Clancy, P; Golledge, J; Koblar, SA; Seto, SW, 2013)
"Our findings suggest that ATR1 blockade alters AII, MMP-1, MMP-8 expression and a marker of elastin degradation in human atheroma, but that the elastin degradation response is not MMP driven."3.79Role of the angiotensin converting enzyme 1/angiotensin II/angiotensin receptor 1 axis in interstitial collagenase expression in human carotid atheroma. ( Clancy, P; Golledge, J; Koblar, SA; Seto, SW, 2013)
"The reduction in cytokine levels in the atheroma supernatant was correlated to a reduction in ERK1/2 expression in the tissue."1.40Angiotensin receptor 1 blockade reduces secretion of inflammation associated cytokines from cultured human carotid atheroma and vascular cells in association with reduced extracellular signal regulated kinase expression and activation. ( Clancy, P; Golledge, J; Koblar, SA, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, S1
Wang, K1
Xu, G1
Ji, J1
Qin, C1
Li, L1
Li, J1
Yi, J1
Liu, H1
Lei, H1
Clancy, P2
Seto, SW1
Koblar, SA2
Golledge, J2
Zhao, Y1
Watanabe, A1
Zhao, S1
Kobayashi, T1
Fukao, K1
Tanaka, Y1
Nakano, T1
Yoshida, T1
Takemoto, H1
Tamaki, N1
Kuge, Y1

Other Studies

5 other studies available for avapro and Atheroma

ArticleYear
The intervention effect of zinc supplementation on irbesartan treatment for atherosclerosis of ApoE-/- mice.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Aor

2016
Dose-Effect of Irbesartan on Cyclooxygenase-2 and Matrix Metalloproteinase-9 Expression in Rabbit Atherosclerosis.
    Journal of cardiovascular pharmacology, 2018, Volume: 71, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Aortic Diseases; Atheroscle

2018
Role of the angiotensin converting enzyme 1/angiotensin II/angiotensin receptor 1 axis in interstitial collagenase expression in human carotid atheroma.
    Atherosclerosis, 2013, Volume: 229, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; B

2013
Suppressive effects of irbesartan on inflammation and apoptosis in atherosclerotic plaques of apoE-/- mice: molecular imaging with 14C-FDG and 99mTc-annexin A5.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Analysis of Variance; Animals; Annexin A5; Apolipoproteins E; Apoptosis; Autoradiography; Azo Compou

2014
Angiotensin receptor 1 blockade reduces secretion of inflammation associated cytokines from cultured human carotid atheroma and vascular cells in association with reduced extracellular signal regulated kinase expression and activation.
    Atherosclerosis, 2014, Volume: 236, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aged; Angiotensin II Type 1 Receptor Blockers; Biphenyl Com

2014